WO2011162843A1 - Medical device inserters and processes of inserting and using medical devices - Google Patents

Medical device inserters and processes of inserting and using medical devices Download PDF

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Publication number
WO2011162843A1
WO2011162843A1 PCT/US2011/029883 US2011029883W WO2011162843A1 WO 2011162843 A1 WO2011162843 A1 WO 2011162843A1 US 2011029883 W US2011029883 W US 2011029883W WO 2011162843 A1 WO2011162843 A1 WO 2011162843A1
Authority
WO
WIPO (PCT)
Prior art keywords
sharp
inserter
sensor
analyte
driver
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2011/029883
Other languages
English (en)
French (fr)
Inventor
Manuel L. Donnay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Diabetes Care Inc
Original Assignee
Abbott Diabetes Care Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44673643&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2011162843(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Diabetes Care Inc filed Critical Abbott Diabetes Care Inc
Priority to CA2766685A priority Critical patent/CA2766685A1/en
Priority to BRPI1105769A priority patent/BRPI1105769A2/pt
Priority to JP2013501503A priority patent/JP2013523217A/ja
Priority to CN201180002616.7A priority patent/CN102639185B/zh
Priority to AU2011269796A priority patent/AU2011269796A1/en
Priority to EP11794386A priority patent/EP2552532A1/en
Priority to IL217129A priority patent/IL217129A0/en
Publication of WO2011162843A1 publication Critical patent/WO2011162843A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

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    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
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    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3468—Trocars; Puncturing needles for implanting or removing devices, e.g. prostheses, implants, seeds, wires
    • A—HUMAN NECESSITIES
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    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6865—Access ports
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    • A61B5/1411—Devices for taking blood samples by percutaneous method, e.g. by lancet
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    • A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
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    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
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    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
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    • A61B5/150274—Manufacture or production processes or steps for blood sampling devices
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    • A61B5/150503—Single-ended needles
    • A61B5/150511—Details of construction of shaft
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    • A61B5/150007—Details
    • A61B5/150847—Communication to or from blood sampling device
    • A61B5/15087—Communication to or from blood sampling device short range, e.g. between console and disposable
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    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101—Details
    • A61B5/15103—Piercing procedure
    • A61B5/15107—Piercing being assisted by a triggering mechanism
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    • A61B5/15101—Details
    • A61B5/15103—Piercing procedure
    • A61B5/15107—Piercing being assisted by a triggering mechanism
    • A61B5/15113—Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
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    • A61B5/15101—Details
    • A61B5/15115—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
    • A61B5/15117—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
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    • A61B5/15101—Details
    • A61B5/15126—Means for controlling the lancing movement, e.g. 2D- or 3D-shaped elements, tooth-shaped elements or sliding guides
    • A61B5/1513—Means for controlling the lancing movement, e.g. 2D- or 3D-shaped elements, tooth-shaped elements or sliding guides comprising linear sliding guides
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    • A61B5/15186—Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
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    • A61B5/15188—Constructional features of reusable driving devices
    • A61B5/1519—Constructional features of reusable driving devices comprising driving means, e.g. a spring, for propelling the piercing unit
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    • A61B5/15186—Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
    • A61B5/15188—Constructional features of reusable driving devices
    • A61B5/15192—Constructional features of reusable driving devices comprising driving means, e.g. a spring, for retracting the lancet unit into the driving device housing
    • A61B5/15194—Constructional features of reusable driving devices comprising driving means, e.g. a spring, for retracting the lancet unit into the driving device housing fully automatically retracted, i.e. the retraction does not require a deliberate action by the user, e.g. by terminating the contact with the patient's skin
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    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
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Definitions

  • Patents, applications and/or publications described herein, including the following patents, applications and/or publications are incorporated herein by reference for all purposes: U.S. Patent Nos. 4,545,382; 4,711,245; 5,262,035; 5,262,305; 5,264,104; 5,320,715; 5,356,786; 5,509,410; 5,543,326; 5,593,852; 5,601,435; 5,628,890; 5,820,551; 5,822,715; 5,899,855; 5,918,603; 6,071,391; 6,103,033; 6,120,676; 6,121,009; 6,134,461; 6,143,164; 6,144,837; 6,161,095; 6,175,752; 6,270,455; 6,284,478; 6,299,757; 6,338,790; 6,377,894; 6,461,496; 6,503,381; 6,514,460; 6,514,718; 6,540,89
  • glucose levels or other analytes such as lactate, oxygen, AIC, or the like
  • the monitoring of glucose is particularly important to individuals with diabetes.
  • Diabetics generally monitor glucose levels to determine if their glucose levels are being maintained within a clinically safe range, and may also use this information to determine if and/or when insulin is needed to reduce glucose levels in their bodies or when additional glucose is needed to raise the level of glucose in their bodies.
  • analyte(s) such as glucose
  • bodily fluid such as in the blood stream or in interstitial fluid ("ISF")
  • ISF interstitial fluid
  • Some of these analyte measuring devices are configured so that at least a portion of the devices are positioned below a skin surface of a user, e.g., in a blood vessel or in the subcutaneous tissue of a user, so that the monitoring is accomplished in vivo.
  • An apparatus for inserting a medical device at least partially through the skin of a subject which includes a first subassembly and a second subassembly.
  • the first subassembly includes a sheath defining a distal surface for placement on the skin of the subject, a handle movable between a proximal position and distal position, a device support for supporting the medical device and defining an aperture therethrough, the device support coupled to the handle, a sharp support for supporting a sharp extending through said aperture and coupled to the device support, and a first driver for biasing the sharp support towards the proximal position.
  • the second subassembly includes a housing configured for removable attachment to the first subassembly, and a second driver for advancing the sharp support towards the distal position.support towards the distal position.
  • the first subassembly and the second subassembly are modular components.
  • the first subassembly is capable of independent operation without the second subassembly.
  • the driver of the first subassembly is capable of operation by a user without the second subassembly.
  • the driver of the first subassembly is actuable by depressing an actuation switch or button.
  • the second subassembly is configured to actuate the actuation switch or button of the first subassembly.
  • the second driver includes a rotatable cam or a torsion spring.
  • the second driver includes either an axial driver and a crank assembly or a compression spring.
  • the first driver includes a compression spring, or a torsion spring.
  • the handle is at least partially disposed surrounding the sheath.
  • a retention member for retaining the device support in the distal position is provided.
  • the device support may be coupled to the handle until the device support reaches a distal position.
  • the first subassembly is configured for a single use.
  • the second subassembly is configured for multiple uses.
  • Embodiments of analyte sensors are provided which include a body having a proximal section and a distal section. The distal section may be longitudinally aligned with the proximal section. An intermediate section may be included between the proximal and distal sections, and in some embodiments the intermediate section is laterally displaced from at least the distal member.
  • the proximal end is received within a needle seat to create an anchor region to allow the sensor body to slide into an opening defined in the insertion sharp but prevent the sensor body from inadvertently slipping out of the insertion needle.
  • a width of the distal section of the sensor body is sized to fit within the opening of the insertion sharp.
  • the opening in the sharp has a diameter of about 20 to about 26 gauge, e.g., 21 gauge to about 25 gauge, where in certain embodiments the sharp is 21 gauge or 23 gauge or 25 gauge.
  • Such sharp may be used with a sensor having a width or diameter— at least the portion that is carried by the sharp— of about .20 mm to about .80 mm, e.g., about .25 mm to about .60 mm, where in some embodiments the width or diameter of least a portion of a sensor is .27 mm or .33 mm or .58 mm.
  • the intermediate member includes a plane-altering portion.
  • the plane-altering portion allows the proximal section of the sensor body to be in a plane different than the distal section of the sensor body.
  • the proximal section and the distal section are in planes substantially perpendicular to each other, e.g., the area may define an angle of about 120° to about 60°, e.g., about 90°.
  • apparatuses for inserting a medical device at least partially through the skin of a subject which include a sheath defining a distal surface for placement on the skin of the subject; a handle movable between a proximal position and distal position; a device support for supporting the medical device and defining an aperture therethrough, the device support coupled to the handle; a sharp support for supporting a sharp extending through said aperture and coupled to the device support; and driver for biasing the sharp support towards the proximal position.
  • the driver includes a compression spring.
  • the handle is at least partially disposed surrounding the sheath.
  • a stop portion for retaining the device support in the distal position is included.
  • the device support is coupled to the handle until the device support reaches a distal position. In some embodiments, the device support is uncoupled from the sharp support when the device support reaches the distal position.
  • a second assembly interfaces with the insertion devices or first subassembly.
  • the second assembly automates the insertion segment motion of the described inserter.
  • the second assembly may include a housing configured for removable attachment to the first subassembly, a handle configured for longitudinal movement with respect to the housing, an actuator configured for longitudinal movement with respect to the housing, a release member either located on the actuator or handle which is actuated upon the handle reaching a predetermined position, a driver element coupled between the handle and the actuator, energized upon distal movement of the handle, which drives the actuator distally once the release member is actuated, and a second driver which is also energized upon distal movement of the handle, that applies a proximal force on the handle that returns the handle to a proximal position after pressure is relieved from the handle post insertion.
  • the second driver coupled through the handle, also provides a proximal force to return the actuator to its proximal position where the release member is reengaged.
  • the first driver includes a compression spring, or a torsion spring.
  • the handle is at least partially disposed surrounding the sheath.
  • a retention member for retaining the device support in the distal position is provided. The device support may be coupled to the handle until the device support reaches a distal position.
  • the first subassembly is configured for a single use.
  • the first subassembly is configured for multiple uses.
  • the second subassembly is configured for multiple uses.
  • FIGURE 1 illustrates analyte monitoring system for real time analyte (e.g., glucose) measurement, data acquisition and/or processing in certain embodiments;
  • analyte e.g., glucose
  • FIGURES 2-3 are views of an electrochemical sensor in accordance with a further embodiment of the disclosed subject matter.
  • FIGURES 4-5 are schematic views of a needle hub in accordance with one embodiment of the disclosed subject matter
  • FIGURE 6 is a distal end view of a sharp in accordance with one embodiment of the disclosed subject matter
  • FIGURE 7 is a side view of a sharp in accordance with one embodiment of the disclosed subject matter
  • FIGURE 8 is a side view of a sharp in accordance with one embodiment of the disclosed subject matter
  • FIGURE 9 is a perspective view with parts separated of an inserter in accordance with one embodiment of the disclosed subject matter
  • FIGURE 10 is a schematic view of an alternate embodiment for forming a sharp to be used in an inserter in accordance with one embodiment of the disclosed subject matter
  • FIGURE 11 is a perspective view of an inserter in accordance with one embodiment of the disclosed subject matter.
  • FIGURE 12 is a perspective view with parts separated of an inserter in accordance with one embodiment of the disclosed subject matter;
  • FIGURE 13 is an enlarged sectional view with parts separated of an inserter in accordance with one embodiment of the disclosed subject matter;
  • FIGURE 14 is a perspective view of another embodiment of an inserter in accordance with the disclosed subject matter.
  • FIGURE 15 is a side view of the inserter of FIGURE 14 in accordance with the disclosed subj ect matter
  • FIGURES 16-17 are cross-sectional views of the inserter of FIGURE 14 in accordance with the disclosed subject matter
  • FIGURES 18-19 are perspective views of an inserter in accordance with another embodiment of the disclosed subject matter
  • FIGURES 20-21 are perspective views of the inserter of the embodiment of FIGURE 18 in combination with the inserter of FIGURE 14 in accordance with another embodiment of the disclosed subject matter;
  • FIGURES 22-24 are side views of the inserter of the embodiment of FIGURE 18 in combination with the inserter of FIGURE 14 in accordance with another embodiment of the disclosed subject matter;
  • FIGURES 25-26 are perspective views of an inserter in accordance with another embodiment of the disclosed subject matter;
  • FIGURES 27-28 are perspective views of the inserter of the embodiment of FIGURE 25 in combination with the inserter of FIGURE 14 in accordance with another embodiment of the disclosed subject matter;
  • FIGURES 29-31 are side views of the inserter of the embodiment of FIGURE 25 in combination with the inserter of FIGURE 14 in accordance with another embodiment of the disclosed subject matter;
  • FIGURE 32 is a side view of an inserter in accordance with another embodiment of the disclosed subject matter.
  • FIGURE 33 is a perspective view of an inserter in accordance with another embodiment of the disclosed subject matter.
  • FIGURES 34-43 are views of the inserter of FIGURES 32-33 showing the inserter actuation process;
  • FIGURE 44 is a cross-sectional view of another inserter in accordance with the disclosed subject matter;
  • FIGURE 45 is an exploded perspective view of the inserter of FIGURE 44 in accordance with the disclosed subject matter
  • FIGURES 46-53 are perspective views of the inserter of FIGURE 44 showing the assembly of various components in accordance with the disclosed subject matter
  • FIGURES 54-58 are cross-sectional views of the inserter of FIGURE 44 in accordance with the disclosed subject matter
  • FIGURE 59 illustrates a process for utilizing a sterilized version of the inserter of FIGURE 44 in accordance with the disclosed subject matter
  • FIGURE 60 illustrates an alternate process for utilizing a sterilized version of the inserter of FIGURE 44 in accordance with the disclosed subject matter
  • FIGURE 61 is a perspective view of an inserter in accordance with the disclosed subject matter;
  • FIGURES 62-66 are cross-sectional views of the inserter of FIGURE 61 in accordance with the disclosed subject matter;
  • FIGURES 67-69 are perspective views of components of the inserter of FIGURE 61 in accordance with the disclosed subject matter;
  • FIGURE 70 is a perspective view of an inserter in accordance with the disclosed subject matter.
  • FIGURE 71 is a perspective view with parts separated of the inserter of FIGURE 70 in accordance with the disclosed subject matter.
  • FIGURES 72-79 are cross-sectional views of the inserter of FIGURE 70 in accordance with the disclosed subject matter. DETAILED DESCRIPTION OF THE EMBODIMENTS
  • embodiments of the present disclosure relate to apparatus for inserting a medical device at least partially into the skin of the patient.
  • Some embodiments relate to in vivo methods and devices for detecting at least one analyte such as glucose in body fluid.
  • embodiments include in vivo analyte sensors configured so that at least a portion of the sensor is positioned in the body of a user (e.g., within the ISF), to obtain information about at least one analyte of the body, e.g., transcutaneously positioned in user's body.
  • an in vivo analyte sensor is coupled to an electronics unit that is maintained on the body of the user to process information obtained from the sensor.
  • analyte information is communicated from a first device such as an on body electronics unit to a second device which may include user interface features, including a display, and/or the like.
  • Information may be communicated from the first device to the second device automatically and/or continuously when the analyte information is available, or may not be communicated automatically and/or continuously, but rather stored or logged in a memory of the first device.
  • analyte information derived by the sensor/on body electronics for example, on body electronics
  • the display of information is selected by the user, while the timing of data communication is not.
  • analyte information is only provided or evident to a user (provided at a user interface device) in some embodiments when desired by the user even though an in vivo analyte sensor automatically and/or continuously monitors the analyte level in vivo, i.e., the sensor automatically monitors analyte such as glucose on a predefined time interval over its usage life.
  • an analyte sensor may be positioned in vivo and coupled to on body electronics for a given sensing period, e.g., about 14 days.
  • the sensor-derived analyte information is automatically communicated from the sensor electronics assembly to a remote monitor device or display device for output to a user throughout the 14 day period according to a schedule programmed at the on body electronics (e.g., about every 1 minute or about every 5 minutes or about every 10 minutes, or the like).
  • sensor- derived analyte information is only communicated from the sensor electronics assembly to a remote monitor device or display device at user-determined times, e.g., whenever a user decides to check analyte information. At such times, a communications system is activated and sensor-derived information is then sent from the on body electronics to the remote device or display device.
  • the information may be communicated from the first device to the second device automatically and/or continuously when the analyte information is available, and the second device stores or logs the received information without presenting or outputting the information to the user.
  • the information is received by the second device from the first device when the information becomes available (e.g., when the sensor detects the analyte level according to a time schedule).
  • the received information is initially stored in the second device and only output to a user interface or an output component of the second device (e.g., display) upon detection of a request for the information on the second device.
  • an inserter as described herein is used to place a sensor electronics assembly on the body so that at least a portion of the in vivo sensor is in contact with bodily fluid such as ISF.
  • sensor derived analyte information may be communicated from the on body electronics to a display device on-demand by powering on the display device (or it may be continually powered), and executing a software algorithm stored in and accessed from a memory of the display device, to generate one or more request commands, control signal or data packet to send to the on body electronics.
  • Display devices may also include programming stored in memory for execution by one or more microprocessors and/or ASICs to generate and transmit the one or more request command, control signal or data packet to send to the on body electronics in response to a user activation of an input mechanism on the display device such as depressing a button on the display device, triggering a soft button associated with the data communication function, and so on.
  • the input mechanism may be alternatively or additionally provided on or in the on body electronics which may be configured for user activation.
  • voice commands or audible signals may be used to prompt or instruct the microprocessor or ASIC to execute the software routine(s) stored in the memory to generate and transmit the one or more request command, control signal or data packet to the on body device.
  • on body electronics and/or display device includes a microphone, a speaker, and processing routines stored in the respective memories of the on body electronics and/or the display device to process the voice commands and/or audible signals.
  • positioning the on body electronics and the display device within a predetermined distance (e.g., close proximity) relative to each other initiates one or more software routines stored in the memory of the display device to generate and transmit a request command, control signal or data packet.
  • Different types and/or forms and/or amounts of information may be sent for each on demand reading, including but not limited to one or more of current analyte level information (i.e., real time or the most recently obtained analyte level information temporally corresponding to the time the reading is initiated), rate of change of an analyte over a predetermined time period, rate of the rate of change of an analyte (acceleration in the rate of change), historical analyte information corresponding to analyte information obtained prior to a given reading and stored in memory of the assembly.
  • Some or all of real time, historical, rate of change, rate of rate of change (such as acceleration or deceleration) information may be sent to a display device for a given reading.
  • the type and/or form and/or amount of information sent to a display device may be preprogrammed and/or unchangeable (e.g., preset at manufacturing), or may not be preprogrammed and/or unchangeable so that it may be selectable and/or changeable in the field one or more times (e.g., by activating a switch of the system, etc).
  • a display device will output a current (real time) sensor-derived analyte value (e.g., in numerical format), a current rate of analyte change (e.g., in the form of an analyte rate indicator such as a arrow pointing in a direction to indicate the current rate), and analyte trend history data based on sensor readings acquired by and stored in memory of on body electronics (e.g., in the form of a graphical trace).
  • the on skin or sensor temperature reading or measurement associated with each on demand reading may be communicated from the on body electronics to the display device.
  • the temperature reading or measurement may not be output or displayed on the display device, but rather, used in conjunction with a software routine executed by the display device to correct or compensate the analyte measurement output to the user on the display device.
  • embodiments include inserters for in vivo analyte sensors and on body electronics that together provide body wearable sensor electronics assemblies.
  • in vivo analyte sensors are fully integrated with on body electronics (fixedly connected during manufacture), while in other embodiments they are separate but connectable post manufacture (e.g., before, during or after sensor insertion into a body).
  • On body electronics may include an in vivo glucose sensor, electronics, battery, and antenna encased (except for the sensor portion that is for in vivo positioning) in a waterproof housing that includes or is attachable to an adhesive pad.
  • the housing withstands immersion in about one meter of water for up to at least 30 minutes.
  • Embodiments include sensor insertion devices, which also may be referred to herein as sensor delivery units, or the like. Insertion devices may retain on body electronics assemblies completely in an interior compartment, i.e., an insertion device may be "pre-loaded" with on body electronics assemblies during the manufacturing process (e.g., on body electronics may be packaged in a sterile interior compartment of an insertion device). In such embodiments, insertion devices may form sensor assembly packages (including sterile packages) for pre-use or new on body electronics assemblies, and insertion devices configured to apply on body electronics assemblies to recipient bodies.
  • sensor insertion devices may retain on body electronics assemblies completely in an interior compartment, i.e., an insertion device may be "pre-loaded" with on body electronics assemblies during the manufacturing process (e.g., on body electronics may be packaged in a sterile interior compartment of an insertion device). In such embodiments, insertion devices may form sensor assembly packages (including sterile packages) for pre-use or new on body electronics assemblies, and insertion devices configured to apply on body electronics assemblies
  • Embodiments include portable handheld display devices, as separate devices and spaced apart from an on body electronics assembly, that collect information from the assemblies and provide sensor derived analyte readings to users. Such devices may also be referred to as meters, readers, monitors, receivers, human interface devices, companions, or the like. Certain embodiments may include an integrated in vitro analyte meter.
  • display devices include one or more wired or wireless communications ports such as USB, serial, parallel, or the like, configured to establish communication between a display device and another unit (e.g., on body electronics, power unit to recharge a battery, a PC, etc).
  • a display device communication port may enable charging a display device battery with a respective charging cable and/or data exchange between a display device and its compatible informatics software.
  • Compatible informatics software in certain embodiments include, for example, but not limited to stand alone or network connection enabled data management software program, resident or running on a display device, personal computer, a server terminal, for example, to perform data analysis, charting, data storage, data archiving and data communication as well as data synchronization.
  • Informatics software in certain embodiments may also include software for executing field upgradable functions to upgrade firmware of a display device and/or on body electronics unit to upgrade the resident software on the display device and/or the on body electronics unit, e.g., with versions of firmware that include additional features and/or include software bugs or errors fixed, etc.
  • Embodiments may include a haptic feedback feature such as a vibration motor or the like, configured so that corresponding notifications (e.g., a successful on- demand reading received at a display device), may be delivered in the form of haptic feedback.
  • Embodiments include programming embedded on a computer readable medium, i.e., computer-based application software (may also be referred to herein as informatics software or programming or the like) that processes analyte information obtained from the system and/or user self-reported data.
  • Application software may be installed on a host computer such as a mobile telephone, PC, an Internet-enabled human interface device such as an Internet-enabled phone, personal digital assistant, or the like, by a display device or an on body electronics unit.
  • Informatics programming may transform data acquired and stored on a display device or on body unit for use by a user.
  • Embodiments of the subject disclosure are described primarily with respect to glucose monitoring devices and systems, and methods of glucose monitoring, for convenience only and such description is in no way intended to limit the scope of the disclosure. It is to be understood that the analyte monitoring system may be configured to monitor a variety of analytes at the same time or at different times.
  • embodiments include devices, systems, kits and/or methods to monitor one or more physiological parameters such as, for example, but not limited to, analyte levels, temperature levels, heart rate, user activity level, over a predetermined monitoring time period. Also provided are methods of manufacturing.
  • Predetermined monitoring time periods may be less than about 1 hour, or may include about 1 hour or more, e.g., about a few hours or more, e.g., about a few days of more, e.g., about 3 or more days, e.g., about 5 days or more, e.g., about 7 days or more, e.g., about 10 days or more, e.g., about 14 days or more, e.g., about several weeks, e.g., about 1 month or more.
  • one or more features of the system may be automatically deactivated or disabled at the on body electronics assembly and/or display device.
  • a predetermined monitoring time period may begin with positioning the sensor in vivo and in contact with a body fluid such as ISF, and/or with the initiation (or powering on to full operational mode) of the on body electronics.
  • Initialization of on body electronics may be implemented with a command generated and transmitted by a display device in response to the activation of a switch and/or by placing the display device within a predetermined distance (e.g., close proximity) to the on body electronics, or by user manual activation of a switch on the on body electronics unit, e.g., depressing a button, or such activation may be caused by the insertion device, e.g., as described in U.S. Patent Application No.
  • the on body electronics retrieves and executes from its memory software routine to fully power on the components of the on body electronics, effectively placing the on body electronics in full operational mode in response to receiving the activation command from the display device. For example, prior to the receipt of the command from the display device, a portion of the components in the on body electronics may be powered by its internal power supply such as a battery while another portion of the components in the on body electronics may be in powered down or maintained in a low power state including no power state, inactive mode, or all components may be in an inactive mode, powered down mode. Upon receipt of the command, the remaining portion (or all) of the components of the on body electronics is switched to active, fully operational mode.
  • Embodiments of on body electronics may include one or more printed circuit boards with electronics including control logic implemented in ASIC, microprocessors, memory, and the like, and transcutaneously positionable analyte sensors forming a single assembly.
  • On body electronics may be configured to provide one or more signals or data packets associated with a monitored analyte level upon detection of a display device of the analyte monitoring system within a predetermined proximity for a period of time (for example, about 2 minutes, e.g., 1 minute or less, e.g., about 30 seconds or less, e.g., about 10 seconds or less, e.g., about 5 seconds or less, e.g., about 2 seconds or less) and/or until a confirmation, such as an audible and/or visual and/or tactile (e.g., vibratory) notification, is output on the display device indicating successful acquisition of the analyte related signal from the on body electronics.
  • a confirmation such as an audible and/or visual and
  • the monitored analyte level may be correlated and/or converted to glucose levels in blood or other fluids such as ISF. Such conversion may be accomplished with the on body electronics, but in many embodiments will be accomplished with display device electronics.
  • glucose level is derived from the monitored analyte level in the ISF.
  • Analyte sensors may be insertable into a vein, artery, or other portion of the body containing analyte. In certain embodiments, analyte sensors may be positioned in contact with ISF to detect the level of analyte, where the detected analyte level may be used to infer the user's glucose level in blood or interstitial tissue.
  • Embodiments include transcutaneous sensors and also wholly implantable sensors and wholly implantable assemblies in which a single assembly including the analyte sensor and electronics are provided in a sealed housing (e.g., hermetically sealed biocompatible housing) for implantation in a user's body for monitoring one or more physiological parameters.
  • a sealed housing e.g., hermetically sealed biocompatible housing
  • Embodiments include analyte monitors that are provided in small, lightweight, battery-powered and electronically-controlled systems. Such systems may be configured to detect physical parameters of subjects, such as signals indicative of in vivo analyte levels using an electrochemical sensor, and collect such signals, with or without processing. Any suitable measurement technique may be used to obtain signals from the sensors, e.g., may detect current, may employ potentiometry, etc.
  • sensing systems may be optical, colorimetric, and the like.
  • the portion of the system that performs this initial processing may be configured to provide the raw or at least initially processed data to another unit for further collection and/or processing. Such provision of data may be effected, for example, by a wired connection, such as an electrical, or by a wireless connection, such as an IR or RF connection.
  • the analyte sensor is in communication with on body electronics.
  • the on-body unit may include a housing in which the on body electronics and at least a portion of the sensor are received.
  • the on-body unit may be separately provided as a physically distinct assembly from a monitor unit, e.g., which displays or otherwise indicates analyte levels to a user.
  • the on-body unit may be configured to provide the analyte levels detected by the sensor and/or other information (such as temperature, sensor life, etc.) over a communication link to the monitor unit.
  • the monitor unit in some embodiments, may include, e.g., a mobile telephone device, an in vitro glucose meter, a personal digital assistant, or other consumer electronics such as MP3 device, camera, radio, personal computer, etc., or other communication-enabled data-processing device.
  • the display unit may perform a variety of functions such as but not limited to data storage and/or processing and/or analysis and/or communication, etc., on the received analyte data to generate information pertaining to the monitored analyte levels and/or process the other information.
  • the monitor unit may incorporate a display screen, which can be used, for example, to display measured analyte levels, and/or an audio component such as a speaker to audibly provide information to a user, and/or a vibration device to provide tactile feedback to a user.
  • an analyte - monitoring system it is also useful for a user of an analyte - monitoring system to be able to see trend indications (including the magnitude and direction of any ongoing trend, e.g., the rate of change of an analyte or other parameter, and the amount of time a subject is above and/or below a threshold, such as a hypoglycemic and/or hyperglycemic threshold, etc.); such data may be displayed either numerically, or by a visual indicator such as an arrow that may vary in visual attributes, like size, shape, color, animation, or direction.
  • the monitor unit may further be adapted to receive information from or about an in vitro analyte test strip, which may be manually or automatically entered into the monitor unit.
  • a monitor unit may incorporate an in vitro analyte test strip port and related electronics in order to be able to make discrete (e.g., blood glucose) measurements using an in vitro test strip (see, e.g., 6,175,752, the disclosure of which is incorporated by reference herein for all purposes).
  • discrete e.g., blood glucose
  • the senor is designed to be attachable and detachable from the on body electronics (and the on-body unit may be reusable), e.g., so that one or more of the components may be reused one or more times, while in other embodiments, the sensor and on body electronics may be provided as an integrated, undetachable package, which may be designed to be disposable after use, i.e., not re-used.
  • FIGURE 1 shows an exemplary in vivo-based analyte monitoring system 100 in accordance with embodiments of the present disclosure.
  • analyte monitoring system 100 includes on body electronics 1100 electrically coupled to in vivo analyte sensor 14 (a proximal portion of which is shown in FIG. 1, and attached to adhesive layer 218 for attachment on a skin surface on the body of a user.
  • body electronics 1100 includes on body housing 122 that defines an interior compartment.
  • insertion device 200 (or insertion devices 300, 400, 2400, 2500, 2700, 3700 described herein) that, when operated, transcutaneously positions a portion of analyte sensor 14 through a skin surface and in fluid contact with ISF, and positions on body electronics 1100 and adhesive layer 218 on a skin surface, as will be described in greater detail herein.
  • analyte sensor 14 and adhesive layer 218 are sealed within the housing of insertion device 200 before use, and in certain embodiments, adhesive layer 218 is also sealed within the housing or the adhesive layer can provide a seal for preserving the sterility of the apparatus. Additional details regarding insertion devices are discussed, e.g., in U.S.
  • analyte monitoring system 100 includes display device 1200 which includes a display 1220 to output information to the user, an input component 1210 such as a button, actuator, a touch sensitive switch, a capacitive switch, pressure sensitive switch, jog wheel or the like, to input data or command to display device 1200 or otherwise control the operation of display device 1200.
  • display-less devices or devices without any user interface components. These devices may be functionalized to store data as a data logger and/or provide a conduit to transfer data from on body electronics and/or a display-less device to another device and/or location.
  • Embodiments will be described herein as display devices for exemplary purposes which are in no way intended to limit the embodiments of the present disclosure. It will be apparent that display-less devices may also be used in certain embodiments.
  • on body electronics 1100 may be configured to store some or all of the monitored analyte related data received from analyte sensor 14 in a memory during the monitoring time period, and maintain it in memory until the usage period ends.
  • stored data is retrieved from on body electronics 1100 at the conclusion of the monitoring time period, for example, after removing analyte sensor 14 from the user by detaching on body electronics 1100 from the skin surface where it was positioned during the monitoring time period.
  • real time monitored analyte level is not communicated to display device 1200 during the monitoring period or otherwise transmitted from on body electronics 1100, but rather, retrieved from on body electronics 1100 after the monitoring time period.
  • input component 1210 of display device 1200 may include a microphone and display device 1200 may include software configured to analyze audio input received from the microphone, such that functions and operation of the display device 1200 may be controlled by voice commands.
  • an output component of display device 1200 includes a speaker for outputting information as audible signals. Similar voice responsive components such as a speaker, microphone and software routines to generate, process and store voice driven signals may be provided to on body electronics 1100.
  • display 1220 and input component 1210 may be integrated into a single component, for example a display that can detect the presence and location of a physical contact touch upon the display such as a touch screen user interface.
  • the user may control the operation of display device 1200 by utilizing a set of pre-programmed motion commands, including, but not limited to, single or double tapping the display, dragging a finger or instrument across the display, motioning multiple fingers or instruments toward one another, motioning multiple fingers or instruments away from one another, etc.
  • a display includes a touch screen having areas of pixels with single or dual function capacitive elements that serve as LCD elements and touch sensors.
  • Display device 1200 also includes data communication port 1230 for wired data communication with external devices such as remote terminal (personal computer) 1700, for example.
  • Example embodiments of the data communication port 1230 include USB port, mini USB port, RS-232 port, Ethernet port, Firewire port, or other similar data communication ports configured to connect to the compatible data cables.
  • Display device 1200 may also include an integrated in vitro glucose meter, including in vitro test strip port 1240 to receive an in vitro glucose test strip for performing in vitro blood glucose measurements.
  • display 1220 in certain embodiments is configured to display a variety of information - some or all of which may be displayed at the same or different time on display 1220.
  • the displayed information is user-selectable so that a user can customize the information shown on a given display screen.
  • Display 1220 may include but is not limited to graphical display 1380, for example, providing a graphical output of glucose values over a monitored time period (which may show important markers such as meals, exercise, sleep, heart rate, blood pressure, etc, numerical display 1320, for example, providing monitored glucose values (acquired or received in response to the request for the information), and trend or directional arrow display 1310 that indicates a rate of analyte change and/or a rate of the rate of analyte change, e.g., by moving locations on display 1220.
  • graphical display 1380 for example, providing a graphical output of glucose values over a monitored time period (which may show important markers such as meals, exercise, sleep, heart rate, blood pressure, etc, numerical display 1320, for example, providing monitored glucose values (acquired or received in response to the request for the information), and trend or directional arrow display 1310 that indicates a rate of analyte change and/or a rate of the rate of analyte change, e.
  • display 1220 may also include date display 1350 providing for example, date information for the user, time of day information display 1390 providing time of day information to the user, battery level indicator display 1330 which graphically shows the condition of the battery (rechargeable or disposable) of the display device 1200, sensor calibration status icon display 1340 for example, in monitoring systems that require periodic, routine or a predetermined number of user calibration events, notifying the user that the analyte sensor calibration is necessary, audio/vibratory settings icon display 1360 for displaying the status of the audio/vibratory output or alarm state, and wireless connectivity status icon display 1370 that provides indication of wireless communication connection with other devices such as on body electronics, data processing module 1600, and/or remote terminal 1700.
  • display 1220 may further include simulated touch screen button 1250, 1260 for accessing menus, changing display graph output configurations or otherwise for controlling the operation of display device 1200.
  • display 1220 of display device 1200 may be additionally, or instead of visual display, configured to output alarms notifications such as alarm and/or alert notifications, glucose values etc, which may be audible, tactile, or any combination thereof.
  • the display device 1200 may include other output components such as a speaker, vibratory output component and the like to provide audible and/or vibratory output indication to the user in addition to the visual output indication provided on display 1220. Further details and other display embodiments can be found in, e.g., U.S. Patent Application No. 12/871,901, U.S. provisional application nos. 61/238,672, 61/247,541, 61/297,625, the disclosures of each of which are incorporated herein by reference for all purposes.
  • on body electronics 1100 in certain embodiments is configured to wirelessly communicate analyte related data (such as, for example, data corresponding to monitored analyte level and/or monitored temperature data, and/or stored historical analyte related data) when on body electronics 1100 receives a command or request signal from display device 1200.
  • analyte related data such as, for example, data corresponding to monitored analyte level and/or monitored temperature data, and/or stored historical analyte related data
  • on body electronics 1100 may be configured to at least periodically broadcast real time data associated with monitored analyte level which is received by display device 1200 when display device 1200 is within communication range of the data broadcast from on body electronics 1100, i.e., it does not need a command or request from a display device to send information.
  • display device 1200 may be configured to transmit one or more commands to on body electronics 1100 to initiate data transfer, and in response, on body electronics 1100 may be configured to wirelessly transmit stored analyte related data collected during the monitoring time period to display device 1200.
  • Display device 1200 may in turn be connected to a remote terminal 1700 such as a personal computer and functions as a data conduit to transfer the stored analyte level information from the on body electronics 1100 to remote terminal 1700.
  • the received data from the on body electronics 1100 may be stored (permanently or temporarily) in one or more memory of the display device 1200.
  • display device 1200 is configured as a data conduit to pass the data received from on body electronics 1100 to remote terminal 1700 that is connected to display device 1200.
  • Remote terminal 1700 may include a personal computer, a server terminal a laptop computer or other suitable data processing devices including software for data management and analysis and communication with the components in the analyte monitoring system 1000.
  • remote terminal 1700 may be connected to a local area network (LAN), a wide area network (WAN), or other data network for uni-directional or bi-directional data communication between remote terminal 1700 and display device 1200 and/or data processing module 1600.
  • LAN local area network
  • WAN wide area network
  • Remote terminal 1700 in certain embodiments may include one or more computer terminals located at a physician's office or a hospital.
  • remote terminal 1700 may be located at a location other than the location of display device 1200.
  • Remote terminal 1700 and display device 1200 could be in different rooms or different buildings.
  • Remote terminal 1700 and display device 1200 could be at least about one mile apart, e.g., at least about 100 miles apart, e.g., at least about 1000 miles apart.
  • remote terminal 1700 could be in the same city as display device 1200, remote terminal 1700 could be in a different city than display device 1200, remote terminal 1700 could be in the same state as display device 1200, remote terminal 1700 could be in a different state than display device 1200, remote terminal 1700 could be in the same country as display device 1200, or remote terminal 1700 could be in a different country than display device 1200, for example.
  • a separate, optional data communication/processing device such as data processing module 1600 may be provided in analyte monitoring system 1000.
  • Data processing module 1600 may include components to communicate using one or more wireless communication protocols such as, for example, but not limited to, infrared (IR) protocol, Bluetooth protocol, Zigbee protocol, and 802.11 wireless LAN protocol. Additional description of communication protocols including those based on Bluetooth protocol and/or Zigbee protocol can be found in U.S. Patent Publication No. 2006/0193375 incorporated herein by reference for all purposes.
  • Data processing module 1600 may further include communication ports, drivers or connectors to establish wired communication with one or more of display device 1200, on body electronics 1100, or remote terminal 1700 including, for example, but not limited to USB connector and/or USB port, Ethernet connector and/or port, FireWire connector and/or port, or RS-232 port and/or connector.
  • data processing module 1600 is programmed to transmit a polling or query signal to on body electronics 1100 at a predetermined time interval (e.g., once every minute, once every five minutes, or the like), and in response, receive the monitored analyte level information from on body electronics 1100.
  • Data processing module 1600 stores in its memory the received analyte level information, and/or relays or retransmits the received information to another device such as display device 1200.
  • data processing module 1600 may be configured as a data relay device to retransmit or pass through the received analyte level data from on body electronics 1100 to display device 1200 or a remote terminal (for example, over a data network such as a cellular or WiFi data network) or both.
  • a data relay device to retransmit or pass through the received analyte level data from on body electronics 1100 to display device 1200 or a remote terminal (for example, over a data network such as a cellular or WiFi data network) or both.
  • on body electronics 1100 and data processing module 1600 may be positioned on the skin surface of the user within a predetermined distance of each other (for example, about 1-12 inches, or about 1-10 inches, or about 1-7 inches, or about 1-5 inches) such that periodic communication between on body electronics 1100 and data processing module 1600 is maintained.
  • data processing module 1600 may be worn on a belt or clothing item of the user, such that the desired distance for communication between the on body electronics 1100 and data processing module 1600 for data communication is maintained.
  • the housing of data processing module 1600 may be configured to couple to or engage with on body electronics 1100 such that the two devices are combined or integrated as a single assembly and positioned on the skin surface.
  • data processing module 1600 is detachably engaged or connected to on body electronics 1100 providing additional modularity such that data processing module 1600 may be optionally removed or reattached as desired.
  • data processing module 1600 is programmed to transmit a command or signal to on body electronics 1100 at a predetermined time interval such as once every minute, or once every 5 minutes or once every 30 minutes or any other suitable or desired programmable time interval to request analyte related data from on body electronics 1100.
  • a predetermined time interval such as once every minute, or once every 5 minutes or once every 30 minutes or any other suitable or desired programmable time interval to request analyte related data from on body electronics 1100.
  • data processing module 1600 receives the requested analyte related data, it stores the received data.
  • analyte monitoring system 1000 may be configured to receive the continuously monitored analyte related information at the programmed or programmable time interval, which is stored and/or displayed to the user.
  • the stored data in data processing module 1600 may be subsequently provided or transmitted to display device 1200, remote terminal 1700 or the like for subsequent data analysis such as identifying frequency of periods of glycemic level excursions over the monitored time period, or the frequency of the alarm event occurrence during the monitored time period, for example, to improve therapy related decisions.
  • the doctor, healthcare provider or the user may adjust or recommend modification to the diet, daily habits and routines such as exercise, and the like.
  • data processing module 1600 transmits a command or signal to on body electronics 1100 to receive the analyte related data in response to a user activation of a switch provided on data processing module 1600 or a user initiated command received from display device 1200.
  • data processing module 1600 is configured to transmit a command or signal to on body electronics 1100 in response to receiving a user initiated command only after a predetermined time interval has elapsed. For example, in certain embodiments, if the user does not initiate communication within a programmed time period, such as, for example about 5 hours from last communication (or 10 hours from the last communication, or 24 hours from the last communication), the data processing module 1600 may be programmed to automatically transmit a request command or signal to on body electronics 1100.
  • data processing module 1600 may be programmed to activate an alarm to notify the user that a predetermined time period of time has elapsed since the last communication between the data processing module 1600 and on body electronics 1100.
  • users or healthcare providers may program or configure data processing module 1600 to provide certain compliance with analyte monitoring regimen, so that frequent determination of analyte levels is maintained or performed by the user.
  • a programmed or programmable alarm condition for example, a detected glucose level monitored by analyte sensor 14 that is outside a predetermined acceptable range indicating a physiological condition which requires attention or intervention for medical treatment or analysis (for example, a hypoglycemic condition, a hyperglycemic condition, an impending hyperglycemic condition or an impending hypoglycemic condition)
  • the one or more output indications may be generated by the control logic or processor of the on body electronics 1100 and output to the user on a user interface of on body electronics 1100 so that corrective action may be timely taken.
  • control logic or microprocessors of on body electronics 1100 include software programs to determine future or anticipated analyte levels based on information obtained from analyte sensor 14, e.g., the current analyte level, the rate of change of the analyte level, the acceleration of the analyte level change, and/or analyte trend information determined based on stored monitored analyte data providing a historical trend or direction of analyte level fluctuation as function time during monitored time period.
  • Predictive alarm parameters may be programmed or programmable in display device 1200, or the on body electronics 1100, or both, and output to the user in advance of anticipating the user's analyte level reaching the future level. This provides the user an opportunity to take timely corrective action.
  • Information such as variation or fluctuation of the monitored analyte level as a function of time over the monitored time period providing analyte trend information, for example, may be determined by one or more control logic or microprocessors of display device 1200, data processing module 1600, and/or remote terminal 1700, and/or on body electronics 1100.
  • Such information may be displayed as, for example, a graph (such as a line graph) to indicate to the user the current and/or historical and/or and predicted future analyte levels as measured and predicted by the analyte monitoring system 1000.
  • Such information may also be displayed as directional arrows (for example, see trend or directional arrow display 1310) or other icon(s), e.g., the position of which on the screen relative to a reference point indicated whether the analyte level is increasing or decreasing as well as the acceleration or deceleration of the increase or decrease in analyte level.
  • This information may be utilized by the user to determine any necessary corrective actions to ensure the analyte level remains within an acceptable and/or clinically safe range.
  • Visual indicators including colors, flashing, fading, etc.
  • audio indicators including a change in pitch, volume, or tone of an audio output and/or vibratory or other tactile indicators may also be incorporated into the display of trend data as means of notifying the user of the current level and/or direction and/or rate of change of the monitored analyte level.
  • the system 1000 may include an algorithm stored on computer readable medium to determine the time it will take to reach a clinically significant level and will output notification in advance of reaching the clinically significant level, e.g., 30 minutes before a clinically significant level is anticipated, and/or 20 minutes, and/or 10 minutes, and/or 5 minutes, and/or 3 minutes, and/or 1 minute, and so on, with outputs increasing in intensity or the like.
  • programmed clinically significant glucose threshold levels e.g., hyperglycemic and/or hypoglycemic levels
  • current analyte level derived by an in vivo analyte sensor the system 1000 may include an algorithm stored on computer readable medium to determine the time it will take to reach a clinically significant level and will output notification in advance of reaching the clinically significant level, e.g., 30 minutes before a clinically significant level is anticipated, and/or 20 minutes, and/or 10 minutes, and/or 5 minutes, and/or 3 minutes, and/or 1 minute, and so on, with outputs
  • software algorithm(s) for execution by data processing module 1600 may be stored in an external memory device such as an SD card, microSD card, compact flash card, XD card, Memory Stick card, Memory Stick Duo card, or USB memory stick/device including executable programs stored in such devices for execution upon connection to the respective one or more of the on body electronics 1100, remote terminal 1700 or display device 1200.
  • software algorithms for execution by data processing module 1600 may be provided to a communication device such as a mobile telephone including, for example, WiFi or Internet enabled smart phones or personal digital assistants (PDAs) as a downloadable application for execution by the downloading communication device.
  • Examples of smart phones include Windows ® , AndroidTM, iPhone ® operating system, Palm ® WebOSTM, Blackberry ® operating system, or Symbian ® operating system based mobile telephones with data network connectivity functionality for data communication over an internet connection and/or a local area network (LAN).
  • PDAs as described above include, for example, portable electronic devices including one or more microprocessors and data communication capability with a user interface (e.g., display/output unit and/or input unit, and configured for performing data processing, data upload/download over the internet, for example.
  • remote terminal 1700 may be configured to provide the executable application software to the one or more of the communication devices described above when communication between the remote terminal 1700 and the devices are established.
  • executable software applications may be provided over-the-air (OTA) as an OTA download such that wired connection to remote terminal 1700 is not necessary.
  • OTA over-the-air
  • executable applications may be automatically downloaded as software download to the communication device, and depending upon the configuration of the communication device, installed on the device for use automatically, or based on user confirmation or acknowledgement on the communication device to execute the installation of the application.
  • the OTA download and installation of software may include software applications and/or routines that are updates or upgrades to the existing functions or features of data processing module 1600 and/or display device 1200.
  • new software and/or software updates such as software patches or fixes, firmware updates or software driver upgrades, among others, for display device 1200 and/or on body electronics 1 100 and/or data processing module 1600 may be provided by remote terminal 1700 when communication between the remote terminal 1700 and display device 1200 and/or data processing module 1600 is established.
  • software upgrades, executable programming changes or modification for on body electronics 1 100 may be received from remote terminal 1700 by one or more of display device 1200 or data processing module 1600, and thereafter, provided to on body electronics 1 100 to update its software or programmable functions.
  • software received and installed in on body electronics 1 100 may include software bug fixes, modification to the previously stalled software parameters (modification to analyte related data storage time interval, resetting or adjusting time base or information of on body electronics 1 100, modification to the transmitted data type, data transmission sequence, or data storage time period, among others). Additional details describing field upgradability of software of portable electronic devices, and data processing are provided in U.S. Application Nos. 12/698, 124, 12/794,721 , 12/699,653, and 12/699,844, and U.S. Provisional Application Nos. 61 ,359,265, and 61/325,155 the disclosure of which is incorporated by reference herein for all purposes.
  • the Sensor may include software bug fixes, modification to the previously stalled software parameters (modification to analyte related data storage time interval, resetting or adjusting time base or information of on body electronics 1 100, modification to the transmitted data type, data transmission sequence, or data storage time period, among others). Additional details describing field upgrad
  • the analyte sensor 14 of the analyte measurement system 100 may be used to monitor levels of a wide variety of analytes.
  • Analytes that may be monitored include, for example, acetylcholine, amylase, bilirubin, cholesterol, chorionic gonadotropin, creatine kinase (e.g., CK-MB), creatine, DNA, fructosamine, glucose, glutamine, growth hormones, hormones, ketones, lactate, peroxide, prostate-specific antigen, prothrombin, RNA, thyroid-stimulating hormone, and troponin.
  • CK-MB creatine kinase
  • the concentration of drugs may also be monitored.
  • antibiotics e.g., gentamicin, vancomycin, and the like
  • digitoxin digoxin
  • digoxin drugs of abuse
  • theophylline drugs of abuse
  • warfarin drugs
  • One or more analyte may be monitored by a given sensor.
  • the analytes may be monitored at the same or different times, which may use the same on body electronics (e.g., simultaneously) or with different on body electronics.
  • sensor 14 is physically positioned in or on the body of a user whose analyte level is being monitored.
  • Sensor 14 may be configured to continuously sample the analyte level of the user and convert the sampled analyte level, e.g., glucose concentration into a corresponding data signal, e.g., a current or voltage, for input into on body electronics.
  • sensor 14 may be configured to sample analyte levels on demand.
  • the on body electronics may amplify, filter, average, and/or otherwise process signal provided by the sensor.
  • FIGURE 2 An embodiment of the sensor 14 is illustrated in FIGURE 2. It is understood that the inserters described herein can be used with other medical devices.
  • sensor 14 includes a substrate which is a dielectric, e.g., a polymer or plastic material, such as polyester or polyamide.
  • the sensor is constructed so that a portion is positionable beneath skin and a portion is above skin.
  • sensor 14 includes an insertion or internal portion 30 and an external or electrical contact portion 32.
  • the contact portion 32 includes several conductive contacts 36, 38, and 40 (herein shown as three contacts) for connection to other electronics, e.g., at the on body electronics 1100. (See Figure 1.)
  • the contacts provided in this embodiment are for a working electrode, a reference electrode, and a counter electrode.
  • two or more working electrodes are provided.
  • the operative portions of these electrodes that is, working electrode, reference electrode, and counter electrode (not individually shown), are provided at the insertion portion, e.g., at the distal end of insertion portion 30, e.g., portion 34.
  • one or more electrodes may be external to the body, e.g., an external counter electrode.
  • the contact and operative portions of the electrodes are connected by circuit traces 42, 44, and 46 running on the surface of the substrate.
  • the traces are provided in channels, or may be embedded within the substrate, or may traverse different sides of the substrate.
  • the conductive contacts, conductive traces, and electrodes are fabricated from conductive material, such as platinum, palladium, gold, carbon, or the like. More than one material may be used for a given sensor. Further details of sensors are described, e.g., in U.S. Patent Nos. 6,175,572 and 6,103,033, which are incorporated by reference herein for all purposes.
  • Sensor 14 may include a proximal retention portion 48.
  • the insertion portion 30 and the proximal retention portion 48 are sized and configured to be positioned with a sharp for installation into the skin of a subject, as described herein.
  • the sensor 14 may be configured to bend ⁇ e.g., along the line B) and therefore be positioned in two substantially perpendicular, intersecting planes. Such bending may occur prior to or during coupling to the on body electronics as described below. (See FIGURE 17).
  • Portions 48 and 52 which provide a path for electrical connections, e.g., the conductive traces, between the proximal and distal portions of the sensor.
  • Sensor 14 is further provided with a notch or cut-out 54.
  • Such configuration facilitates the sensor 14 to bend ⁇ e.g., along the line indicated by line B) such that retention portion 48 remains upright and therefore be positioned in two substantially perpendicular, intersecting planes, as illustrated in FIGURE 3.
  • the sensor tab 50 can be encased in the on body housing 122 to aid in securing and positioning the sensor 14.
  • Proximal retention portion 48 maintains its longitudinal alignment with insertion portion 30 for positioning within an insertion sharp.
  • Embodiments of analyte sensors have been described herein to operate electrochemically, through an arrangement of electrodes having chemical sensing layers applied thereto, by generating an electrical current proportional to the volume of a redox reaction of the analyte (and indicative of analyte concentration), catalyzed by an analyte- specific oxidizing enzyme.
  • Embodiments exist in which the number of electrodes provided to bring about and detect the level of these reactions is two, three, or a greater number.
  • other types of sensors may be employed as described herein.
  • a portion of sensor 14 may be situated above the surface of the skin, with a distal portion 30 penetrating through the skin and into the subcutaneous space in contact with the user's biofluid, such as ISF. Further details regarding the electrochemistry of sensor 14 is provided in U.S. Patent Nos. 5,264, 104; 5,356,786; 5,262,035; 5,320,725; and 6,990,366, each of which is incorporated by reference herein for all purposes.
  • the senor is implantable into a subject's body for a usage period (e.g., a minute or more, at least one day or more, about one to about 30 days or even longer, about three to about fourteen days, about three to about seven days, or in some embodiments, longer periods of up to several weeks) to contact and monitor an analyte present in a biological fluid.
  • the sensor can be disposed in a subject at a variety of sites (e.g., abdomen, upper arm, thigh, etc.), including intramuscularly, transcutaneously, intravascularly, or in a body cavity.
  • sensor 14 is employed by insertion and/or implantation into a user's body for some usage period.
  • the substrate may be formed from a relatively flexible material.
  • FIGURES 2-3 have three electrodes, other embodiments can include a fewer or greater number of electrodes.
  • a two-electrode sensor can be utilized.
  • the sensor 14 may be externally-powered and allow a current to pass which current is proportional to the amount of analyte present.
  • the sensor 14 itself may act as a current source in some embodiments.
  • the sensor may be self-biasing and there may be no need for a reference electrode.
  • An exemplary self-powered, two-electrode sensor is described in U.S. Patent Application Serial No.
  • the level of current provided by a self-powered sensor may be low, for example, on the order of nanoamperes, in certain embodiments.
  • Insertion assemblies are provided, which are used to install a medical device to the subject.
  • an insertion assembly includes an inserter and the medical device itself.
  • the inserter can be configured to insert various medical devices into the subject, such as for example, an analyte sensor, an infusion set, or a cannula.
  • the inserter can be configured to install a combination of such devices, e.g., a combined sensor/infusion set, etc., at the same or different times or locations.
  • a given inserter can be configured to install a first device and a second device at different times. In this regard, the inserter can be reusable.
  • an inserter may be modifiable to be used with more than one medical device, to include more than one type of medical device, e.g., by attaching an adapter and/or detaching a portion of an inserter.
  • the inserter can install the medical device in, under, or through the skin of the subject, or place the medical device on the surface of the skin.
  • the medical device can include features or structures, e.g., barbs, tabs, adhesive, etc., to maintain the device in position with respect to the skin after insertion.
  • the inserter device may also be used as a lancet, e.g., to pierce the skin without inserting or installing a medical device.
  • an insertion assembly includes an inserter, an analyte sensor, and a power supply.
  • the power supply may be inserted simultaneously with the analyte sensor by the inserter.
  • the battery is installed after or before installation of the analyte sensor.
  • the power supply may be applied by the inserter or separately.
  • the power supply may be used to provide a current or a potential to the sensor and/or to provide power for communication of one or more signals to the monitor unit.
  • an insertion assembly includes an inserter, a medical device such as an analyte sensor, and on-body electronics.
  • the on-body electronics may be deployed and/or installed simultaneously with the analyte sensor by the inserter.
  • the on-body electronics are installed after or before installation of the analyte sensor.
  • the analyte sensor may be installed by the inserter, and the on-body electronics may be subsequently installed.
  • the on-body electronics provide a voltage or current to the analyte sensor.
  • the on-body electronics process signals provided by the analyte sensor.
  • the on-body electronics electronics may include communications functionality for providing signal relating to signal provided by the analyte sensor to a further component, such as, e.g., a monitor unit, a computer, or other component.
  • communications circuitry such as an RFID antenna, is provided. The power supply may be used to power some or all of these functions.
  • power is provided from the monitor unit, e.g., via inductive coupling.
  • An inserter can include a plurality of different components.
  • an inserter may include one or more components for advancing a sharp towards the skin of the subject.
  • the sensor and on-body electronics may be supported by a support structure, such as a carriage.
  • a driver may be provided for advancing the sharp and/or the analyte sensor/support structure.
  • the actuator is directly or indirectly coupled to the sharp and/or support structure, such that manual force applied by the user to the actuator is transferred to the sharp and/or support structure.
  • the applied force drives the sharp and/or support structure between a retracted position (within the inserter) and an advanced position (towards the skin of the subject).
  • the senor and on-body electronics is maintained in a retracted position prior to installation by contacting projections extending inwardly from a sheath.
  • the sensor and on-body electronics are temporarily maintained operative ly between the support structure and the projections disposed on the interior wall of the sheath.
  • An inserter can also include one or more components for retracting the sharp, while allowing the analyte sensor and optional on-body electronics to remain on the subject.
  • the components for retracting the sharp can include a retractor. It is understood that the retractor and the actuator may be the same structure or include some common components.
  • the retractor is directly or indirectly coupled to the sharp such that the manual force applied by the user is transferred from the retractor to the sharp to retract the sharp from the skin.
  • a drive assembly may be provided to retract the sharp.
  • the drive assembly may include a spring, motor, hydraulic piston, etc., to retract the sharp away from the skin of the subject.
  • the drive assembly may also include a linear drive component.
  • the retractor withdraws the sharp upon actuation by the user. In such cases, the user actuates the retractor when it is desired to withdraw the sharp.
  • the retractor may include a release switch. Upon activation of the release switch, the drive assembly, e.g.
  • the spring or other driver retracts the sharp from the skin.
  • the retractor and the actuator include common components. After activating the actuator to advance the sharp and the analyte sensor, the user releases the actuator, which allows the drive assembly to withdraw the sharp from the skin.
  • the retractor withdraws the sharp without further user interaction after actuation of insertion.
  • the inserter may include features or components which automatically retract the sharp upon advancement of the sharp and support structure by a predetermined amount. Inserter devices, in which no further action by the user is required to initiate withdrawal of the sharp after insertion, are referred to herein as having "automatic" withdrawal of the sharp. Inserter Devices
  • Needle hub 136 supports sharp 124, having a sharpened distal portion 160.
  • a longitudinal wall opening or gap 162 is provided in at least a portion of the wall of the sharp 124.
  • the length N of the gap 162 is selected to be commensurate with the length of the insertion portion 30 through to the proximal retention portion 48 of the sensor, and in certain embodiments may be about 3 mm to about 50 mm, e.g., about 5 mm, or about 10 mm, or about 15 mm, or about 20 mm.
  • the length L of the sharp 124 may be about 3 mm to about 50 mm, e.g., 5 mm or more, or about 10 mm, or about 20 mm, or about 30 mm, or about 50 mm, and is selected based upon the length of the insertion portion 30 of a sensor and the desired depth of the insertion portion 30 of the sensor 14. In some embodiments, the distance or spacing between the two edges of the gap is about 0.2 mm to about 0.5 mm, e.g., about 0.22 mm, about 0.25 mm, etc. [00136] The distal portion 160 of sharp 124 is illustrated in greater detail in FIGURES 6-8.
  • sharp 124 has a substantially “C”- or “U”-shaped profile in this embodiment, but may have other configurations, e.g., substantially “V”- shaped.
  • a longitudinal gap 162 is provided in the wall of the sharp 124.
  • FIGURE 7 illustrates distal portion 160 is provided with an angled tip.
  • the angled tip may be provided with a first angled tip portion 164 and a second steep-angled tip portion 166.
  • the exemplary configuration which includes multiple edges and faces, provides a sharp point to reduce penetration force, trauma, and bleeding for the subject.
  • the distal section of the sensor body has a width sized to fit within the notch 162 of the insertion sharp 124 having a diameter less than about 20 to about 26 gauge, e.g., 21 gauge to about 25 gauge, where in certain embodiments the sharp is 21 gauge or 23 gauge or 25 gauge.
  • Such sharp may be used with a sensor having a width or diameter— at least the portion that is carried by the sharp— of about .20 mm to about .80 mm, e.g., about .25 mm to about .60 mm, where in some embodiments the width or diameter of at least a portion of a sensor is .27 mm or .33 mm or .58 mm.
  • sharp 124 is fabricated from a sheet of metal and folded into a substantially "V,” "U” or “C” configuration in cross-section.
  • Various technologies can be used to manufacture a folded sheet of metal to form sharp 124.
  • etched- sheet metal technology can be used to form the sharp 124.
  • the sharp can be formed having a very sharp edge so that penetration through the skin during insertion is less painful.
  • a progressive die technology may be utilized to form a complex sheet- metal shape that has a sharp edge as depicted in FIGURE 9.
  • the sharp 124 can be molded with a plastic cap so that the sharp can be handled during the inserter assembly process.
  • the die cut sharp may be molded with plastic to reinforce the "V,” “U” or “C” shaped sheet metal configuration.
  • a laser-cut sharp can be formed. In this manner, the laser can be used to form the wall opening or gap 162 and first-angled tip portion 164 and a second, steep-angled tip portion 166.
  • a sharp 124 may be formed from a standard hypodermic needle utilizing the method depicted in FIGURE 10. First, the hypodermic needle (having a circular cross-section) is cut to the desired length for sharp 124. Next, the hypodermic needle is compressed so that its cross-section is permanently deformed from a circular shape to an oval shape. The tip of the hypodermic needle is then ground to a bevel to produce a sharp point to reduce the required penetration force, as previously discussed. Finally, the top section of the needle is removed by appropriate techniques (e.g., grinding, electropolishing, etc.). The resulting sharp 124 has a "U"-shaped configuration and provides ample space for the insertion of sensor 14.
  • the tip-grinding step and the compression step may be carried out in reversed order.
  • a user may initially start with a larger diameter hypodermic needle so that the finished sharp 124 will have similar dimensions to the previously described sharps.
  • FIGURES 1 1-12 illustrate the position of on body housing 122 with respect to the needle hub 136 and sharp 124.
  • the on body housing 122 can be configured to hold at least a portion of sensor 14 and sensor control unit 12.
  • the sharp 124 extends through an aperture 168 in the on body housing 122.
  • the sharp 124 is uncoupled to on body housing 122.
  • the distal portion of sensor 14 is positioned with the sharp 124.
  • electronics 80 of the sensor control unit 12 e.g., a printed circuit board containing electronics components of the on-body unit 16
  • sensor hub 123 are positioned within on body housing 122.
  • Sensor 14 may include a positioning structure, or slit 127, which receives a positioning member, such as tab 129 of sensor hub 123.
  • a power supply 82 such as a battery, e.g., a single-use disposable battery or rechargeable battery, is provided.
  • the power supply 82 is used to provide potential or current to the sensor in some embodiments.
  • a passive communications protocol such as passive RFID is used
  • no power supply is provided for the communications.
  • Such power is provided by the monitor unit 18.
  • the sensor control unit is used to transmit one or more signals
  • one or more power supplies may be used to provide power for such communications circuitry.
  • the active operational life of the battery may exceed the active operational life of the sensor 14.
  • FIGURE 13 illustrates in cross-section the orientation of the on body housing 122 with respect to the sharp 124 of an inserter, such as inserter 500 depicted in FIGURES 13-17.
  • sensor 14 is disposed in a substantially bent configuration in some embodiments, such that a portion of the sensor, e.g., the insertion portion 30 and the proximal retention portion 48, are substantially vertical (i.e., substantially aligned with the longitudinal axis of an inserter and substantially perpendicular to the skin surface) and the contact portion 32 (shown in profile) is oriented in a substantially horizontal configuration, and in electrical contact with the data- processing unit electronics, such as circuit 80.
  • the sensor tab 50 can be encased in the plastic of the on body housing 122 (., "overmolded") and secured in place.
  • the notch 56 provides further stability to the sensor 14, e.g., by allowing the sensor tab 50 to be encased by the material of the on body housing 122, and further provides a means for vertically orienting the sensor 14 during mounting, by allowing vertical positioning of the notch 56 with respect to a vertical landmark of the on body housing 122.
  • the sensor 14, mounted with the on body housing 122 can be disposed within a recess of the carriage 130 such as a concave recess in the carriage 130.
  • the senor 14, mounted with the on body housing 122 can be disposed between the support structure and one or more projections extending from the wall of the sheath.
  • the sensor 14, mounted with the on body housing 122 can be held in position by a releasable friction fit coupling to the sharp 124. In this manner, the carriage need not have a recess within which the sensor mounted with the sensor housing is disposed.
  • the sharp 124 extends through a longitudinal aperture 168 formed in a carriage 130.
  • the aperture 168 is appropriately sized, such that neither the sharp 124 nor needle hub 136 is in contact with the carriage 130.
  • a friction fit may be provided between the aperture and the sharp.
  • the insertion portion 30 and proximal retention portion 48 of the sensor 14 are disposed within a longitudinal bore 162 within the sharp 124 (See, e.g., FIGURE 6).
  • the proximal retention portion 48 is disposed within the longitudinal bore of the sharp 124 and provides additional stability to the mounting of the sensor 14 within the sharp 124.
  • the longitudinal wall gap or opening 162 of sharp 124 is aligned with the sensor 14, such that the tab 50 and the contact portion 32 extend laterally outward from the sharp 124.
  • inserter 500 An embodiment of an inserter is illustrated in FIGURES 14-17 and is designated inserter 500.
  • inserter 500 has a maximum diameter of about 30 mm to about 60 mm, e.g., about 40 mm, about 43 mm, about 43.5 mm, about 50.5 mm, about 54.5 mm, etc.
  • inserter 500 has a maximum height of about 40 mm to about 80 mm, e.g., about 44 mm, about 46 mm, about 50 mm, about 53 mm, about 67 mm, about 71 mm, etc.
  • inserter 500 has a volume of about 35 cm 3 to about 110 cm 3 , e.g., about 40 cm 3 , about 41 cm 3 , about 50 cm 3 , about 60 cm 3 , about 61 cm 3 , about 62 cm 3 , about 69 cm 3 , about 70 cm 3 , about 79 cm 3 , about 90 cm 3 , about 106 cm 3 , etc.
  • the maximum height is measured from actuator 514 to the distal surface 512 of sheath 542.
  • the volume is measured as the bellows portion 502 and the portion of the sheath 542 that protrudes from bellows portion 502.
  • Inserter 500 includes, a bellows portion 502, a sheath 542, and a removable distal cap 504 for maintaining a sterile environment for the medical device and sharp housed therein. As illustrated in FIGURE 15, distal cap 504 is shown removed from sheath 542. Sheath 542 defines a distal surface 512 for placement on the skin of a subject. Inserter 500 may be utilized to advance a medical device into the skin of the subject. In some embodiments, bellows portion 502 is compressed in order to advance the medical device into the skin of the subject. Bellows portion 502 includes a series of concentric folds, including raised portions 516 and folded portions 518.
  • Inserter 500 is illustrated in cross-section in FIGURE 16 prior to use and prior to removal of cap 504, which is attached to sheath 542 via inter-engagement of threads 510 on sheath and threads on cap 504.
  • Cap 504 includes a desiccant tablet 590.
  • Cap 504 may further include a receptacle for maintaining the position of the sharp 524 within the sheath 542 prior to use.
  • the inserter 500 includes an initial configuration in which the bellows portion 502 is disposed in a relaxed, extended position. In such configuration, the sharp 524 is disposed in a position spaced apart from the aperture 520 of the adhesive layer 518.
  • the proximal end portion of the bellows portion 502 includes a button or actuator portion 514. Extending distally from the actuator portion 514 are side walls 528 and needle hub 536. Downward force on the actuator portion 514 causes a downward force on the needle hub 536 and on the carriage 530 (through coupling to side walls 528).
  • Carriage 530 includes a recess 532 for reception of the on body housing 122 therein. Additionally, carriage 530 includes laterally acting spring arms that engage detent features on the on body housing 122 periphery and allow for easy release of on body housing 122 upon completion of insertion.
  • Sharp 524 extends longitudinally from needle hub 536 within the inserter 500. In some embodiments, the sharp is supported at an oblique angle, between about 0° and 90° with respect to the skin surface.
  • FIGURE 17 illustrates inserter 500 in cross-section during insertion.
  • Depression of bellows portion 502 with respect to sheath 542 against the bias of spring 546 causes distal longitudinal movement of the carriage 530 and sharp 524 from a proximal position toward a distal position.
  • spring 546 is compressed between an upper (proximal) portion adjacent to actuator 514 and a lower (distal) portion adjacent to sheath 542.
  • the sharp 524 As the sharp 524 is urged distally, it carries the sensor insertion portion 30 of sensor 14 (FIGURE 12) into the subcutaneous portion of the subject's skin S.
  • a layer of adhesive between carriage 530 and sheath 542 may be used, requiring the user to exceed a minimum force threshold to break the adhesive bond, thus allowing distal motion of carriage to occur.
  • the bias of spring 546 provides an upward (proximal) force, which permits sharp 524 to withdraw from the skin S of the subject.
  • bellows 502 may provide the entire upward (proximal) force to withdraw sharp 524 from the skin S.
  • driver apparatus 3600 An exemplary driver apparatus is illustrated in FIGURES 18-24 and designated driver apparatus 3600. It is understood that driver apparatus 3600 as described herein (as well as driver apparatuses 3700, 3800, 3900, and 4000) is designed for use with any inserter described herein, such as, e.g., inserter 500 (see FIGURES 14- 17) or alternatively inserter 2400 (see FIGURES 44-58). Moreover, in certain embodiments, driver apparatus 3600 (and 3700, 3800, 3900, and 4000) may be configured for use with any inserter apparatus which includes an actuator button or driver for advancing a medical device at least partially into the skin of a patient.
  • driver apparatus 3600 (and 3700) is illustrated in cooperation with inserter 500, it is understood that such combination of devices is not intended to encompass all combinations of driver apparatuses and inserters.
  • driver apparatus 3900 (and 4000) is illustrated with inserter 2400, it is understood that such combination of devices is not intended to encompass all combinations of driver apparatuses and inserters.
  • the driver apparatuses disclosed herein provide, among other features, a "button pushing" capability in which the driver apparatus which may be coupled to the actuator button or driver of the inserter to which the driver apparatus is attached.
  • the driver apparatus and the inserter may each be capable of independent operation.
  • the inserter may include an actuator button or switch to advance the medical device into the skin of the patient without use of the driver apparatus.
  • the driver apparatus to the extent is provides an actuation capability, may be used with any inserter which has an actuation button that may be contacted by the driver of the driver apparatus.
  • the modularity allows the driver apparatus to be designed for multiple uses, and the inserter device is capable of a single use.
  • the inserter is also capable of multiple uses, for example, by replacing the sensor and/or on-body housing with each use.
  • Driver apparatus 3600 includes a housing 3602 for positioning with respect to an inserter.
  • a loading element 3604 longitudinally movable with respect to housing 3602— is provided.
  • driver apparatus 3600 is provided with an actuator, e.g., rotating cam 3606, which provides automatic actuation of an inserter.
  • arming button 3620 is pressed (in direction of arrow E) to connect rack 3610 with pinion 3612 (FIGURE 18).
  • loading element 3604 is depressed downwardly (direction of arrow D) to rotate cam 3606 in a first direction F against the bias of torsion spring 3614.
  • Firing button 3618 maintains the spring in the loaded position until pressed.
  • the driver apparatus 3600 is positioned with respect to an inserter 500.
  • inserter 500 is illustrated in FIGURES 20-24, it is understood that any inserter may be used with driver apparatus 3600.
  • the dimensions of the housing 3602 and the location and shape of cam 3606 are selected to interact with the dimensions of the inserter in some embodiments.
  • the housing 3602 may be designed for snap-fit or friction-fit cooperation with the sheath 542 of inserter 500.
  • FIGURES 22-24 illustrate the sequence of motions of the driver apparatus 3600 to drive sharp 524 into the skin of the subject.
  • torsion spring 3614 upon depressing release button 3618, torsion spring 3614 is released, thereby driving rotation of cam 3606 in the direction J with the bias of the torsion spring 3614.
  • Cam 3606 includes a surface having a protrusion 3607. As illustrated in FIGURE 23, further rotation of cam 3606 causes protrusion 3607 to engage actuator button 514 of inserter 500.
  • driver apparatus 3700 is a reusable apparatus, whereas the inserter may be a disposable device.
  • Driver apparatus 3700 is substantially identical to driver apparatus 3600, with the substantial differences noted herein and indicated in the accompanying figures.
  • driver apparatus 3700 includes a housing 3702 for positioning with respect to an inserter.
  • a loading element 3704 longitudinally movable with respect to an upper housing 3705— is provided.
  • actuator 3706 is a reciprocal element that provides automatic actuation of an inserter.
  • loading element 3704 is advanced laterally (direction of arrow K) along a track 3710 against the normal bias of a drive spring 3714.
  • a locking mechanism 3718 maintains the loading of spring 3714.
  • the driver apparatus 3700 is positioned with respect to an inserter 500.
  • inserter 500 is illustrated in FIGURES 27-31, it is understood that any inserters may be used with driver apparatus 3700.
  • cap 504 of inserter 500 is removed (not shown), thereby allowing placement of adhesive 518 (not shown) on the skin of the subject.
  • release button 3718 may be depressed (arrow L).
  • FIGURES 29-31 illustrate the sequence of motions of the driver apparatus 3700 to drive the sharp 524 into the skin of the subject (see FIGURE 16).
  • drive spring 3714 is released, thereby driving sliding member 3707 in the direction M with the bias of the spring 3714.
  • Sliding member 3707 is restrained to lateral motion due its positioning in track 3710.
  • actuator 3706 is restrained to longitudinal motion due to its positioning in track 3709.
  • Sliding member 3707 is coupled to actuator 3706 by a crank member 3720, which is pivotally connected to one end to sliding member 3707 and at the other end to actuator 3706.
  • driver apparatus 3800 A driver apparatus for actuation of inserters is illustrated in FIGURES 32-43 and designated driver apparatus 3800.
  • driver apparatus 3800 is a reusable apparatus, whereas the inserter may inserter 500 described herein.
  • Driver apparatus 3800 is substantially identical to actuators 3600 and 3700, with the substantial differences noted herein and indicated in the accompanying figures.
  • driver apparatus 3800 includes a housing 3802 for positioning with respect to an inserter, such as inserter 500 described herein.
  • a loading element 3804 is provided which is longitudinally movable with respect to housing 3802. Depression of the loading element causes a rotor 3808 to rotate against the bias of a torsion spring (not shown).
  • a locking element (not shown) maintains the loading of the torsion spring.
  • driver apparatus 3800 includes trigger 3810, cam 3808, arming button 3812, torsion spring 3814, shaft 3816, pawl 3818, actuator 3806, and return spring 3820.
  • loading element 3804 (not shown) is pressed, causing arming button 3812 to be pushed down, winding shaft 3816 and thus torsion spring 3814 (FIGURE 35).
  • Pawl 3818 locks shaft 3816 into place (FIGURE 36).
  • arming button 3812 After a user depresses loading element 3804, arming button 3812 returns to its original position while shaft 3816 is held in place by pawl 3818 (FIGURE 37).
  • loading element 3804 is used to alternately depress arming button 3812 and trigger 3810.
  • Cam 3808 is then driven forward by torsion spring 3814 (FIGURE 38).
  • a first loading element is used to depress arming button 3812, and a second loading element is used to depress trigger 3810 (not shown).
  • cam 3808 As cam 3808 rotates, it pushes down on actuator 3806 (FIGURES 39-40). At the end of the stroke, there is a slight dwell. This allows the sensor body to be held and pressed onto the adhesive skin patch (FIGURE 41). After a full rotation, cam 3808 is stopped by trigger 3810 as shown in FIGURE 43. Return spring 3820 pushes actuator 3806 back up, releasing pressure on the inserter. When trigger 3810 is released by the subject, cam 3808 continues to rotate until it is in the home position, thereby allowing driver apparatus 3800 to be used again (FIGURE 43).
  • inserter 500 supports an on body housing 122 and sensor 14.
  • a sharp (not shown) is used to advance the sensor into the skin of the patient.
  • Actuator 3806 contacts actuator 114 (substantially identical to actuator 514) of inserter 500 to drive the sharp and sensor downward towards the subject's skin.
  • inserter 2400 in accordance with another exemplary embodiment is illustrated in FIGURE 44.
  • inserter 2400 has a maximum diameter of about 30 mm to about 60 mm, e.g., about 40 mm, about 43 mm, about 43.5 mm, about 50.5 mm, about 54.5 mm, etc.
  • inserter 2400 has a maximum height of about 40 mm to about 80 mm, e.g., about 44 mm, about 46 mm, about 50 mm, about 53 mm, about 67 mm, about 71 mm, etc.
  • inserter 2400 has a volume of about 35 cm 3 to about 110 cm 3 , e.g., about 40 cm 3 , about 41 cm 3 , about 50
  • inserter 2400 includes a housing 2402 and a removable distal cap 2412 for protecting the medical device and sharphoused therein.
  • Housing 2402 and distal cap 2412 may be fabricated from any suitable materials such as metal, plastic, etc.
  • cap 2412 may be fabricated from a polymer or plastic material.
  • inserter 2400 An exploded view of the components of inserter 2400 is illustrated in FIGURE 45.
  • inserter 2400 generally comprises plunger 2405, spring 2406, housing 2402, sharp 2404, on body housing 122, sharp holder 2408, adhesive patch 218, and cap 2412 when fully assembled.
  • FIGURE 46 A more detailed view of sharp holder 2408 is shown in FIGURE 46. Needle holder 2408 retains sharp 2404 in a fixed position with respect to itself within inserter 2400, thereby allowing it to safely penetrate a subject's skin during later use.
  • sharp 2404 is inserted through an opening in on body housing 122 as shown in FIGURE 47. Needle holder 2408 prevents sharp 2404 from being fully inserted through on body housing 122.
  • on body housing 122 includes an analyte sensor 14 and a sensor control unit 12.
  • plunger 2405, spring 2406, and housing 2402 are assembled as shown in FIGURES 48-50.
  • Plunger 2405 contains a spring retention member which is inserted through the center of spring 2406. Lip 2414 of plunger 2405 engages inner wall 2416 (not shown) of housing 2402 when assembled (FIGURE 44). This causes spring 2406 to be contained between lip 2418 of housing member 2402 and the bottom surface 2424 (not shown) of plunger 2405.
  • the resulting sub-assembly of inserter 2400 allows plunger 2405 to move between a proximal position, with spring 2406 fully extended, and a distal position, wherein bottom surface 2424 engages wall 2426 of housing 2402.
  • FIGURE 47 The sensor housing assembly shown in FIGURE 47 is then inserted into the inserter sub-assembly shown in FIGURES 48-50.
  • FIGURE 50 on body housing 122 is inserted into housing 2402 with the tip of sharp 2404 pointing away from plunger 2405.
  • the resulting assembly is depicted in FIGURE 51.
  • FIGURE 44 grooves on sharp holder 2408 engage tabs 2422 (not shown) on plunger 2405.
  • the on body housing 122 is axially retained in the housing 2402 by the housing arms detent features 2440 (not shown).
  • adhesive patch 218 is placed over the opening of housing 2402 and cap 2412 is snap fit over housing 2402 as shown in FIGURE 52.
  • the fully assembled inserter 2400 is depicted in FIGURE 53.
  • adhesive pad 218 has an adhesive material on both faces.
  • a central aperture 220 may be provided in adhesive pad 218 to allow sharp 2404 to be deployed into the skin of a subject. During insertion, sharp 2404 passes through aperture 220 and into the skin of the subject carrying at least the sensor with it.
  • FIGURE 54 illustrates inserter 2400 in cross-section, in an initial configuration prior to use, after removal of the distal cap 2412.
  • sharp 2404 extends longitudinally within the inserter 2400.
  • sharp 2404 is supported at an oblique angle, e.g., between about 0° and 90° with respect to the skin surface.
  • sharp 2404 is a solid needle.
  • sharp 2404 is provided with a substantially cylindrical configuration defining an interior bore, e.g., a rigid cylindrical member or a hypodermic-style needle.
  • Sharp 2404 may also be provided with an elongated longitudinal opening or gap in the wall.
  • sharp 2404 is a fabricated from a sheet of metal and folded into a substantially "V,” "U” or "C” configuration in cross-section to define the longitudinal recess.
  • Depression of plunger 2405 causes distal longitudinal movement of on body housing 122 and sharp 2404 from a proximal position to a distal position. During such downward, distal movement, spring 2406 is further compressed between lip 2418 and bottom surface 2424.
  • Detent 2440 provides a minimum force threshold to overcome before on body housing 122 can continue on its downward distal movement. Beyond a minimum force threshold, detent 2440 is pushed outward by on body housing 122, and on body housing 122 then transitions onto ramp 2442. The friction between on body housing 122 and ramp 2442 of the housing hold the on body housing 122 up against plunger 2405.
  • depression of plunger 2405 advances the inserter 2400 from an initial configuration to a deployed configuration.
  • Contact of plunger 2405 and hub 2408 during depression of plunger 2405 imposes a downward force and consequential distal movement of sharp 2404.
  • Contact of plunger 2405 and on body housing 122 during depression of plunger 2405 imposes a downward force and consequential distal movement of on body housing 122.
  • Lip features 2414 of plunger 2405 maintains parallelism of on body housing 122 to subject skin S during distal movement.
  • bottom surface 2424 engages wall 2426 and prevents further downward movement.
  • the distal (lower) surface of on body housing 122 engages the upper surface of adhesive pad 218, thereby becoming adhered to the skin surface S of the subject.
  • spring 2406 urges pusher 2405 toward its proximal position as shown in FIGURE 57, leaving on body housing 122 adhered to the skin surface S of the subject.
  • Tabs 2427 (not shown) provide additional force on on body housing 122 to assist holding it to adhesive patch 218 while the sharp 2404 is withdrawn through on body housing 122.
  • the upward force exerted by spring 2406 returns inserter 2400 to its initial configuration as illustrated in FIGURE 58.
  • inserter 2400 may be distributed in a sterilized package 2480 as depicted in FIGURE 59.
  • a user would first clean the insertion site on the skin with alcohol. The subject would then remove inserter 2400 from sterilized package 2480 as shown in step 1. Next a subject would place the inserter on the insertion site and push down on plunger 2405 until on body housing 122 is adhered to the subject's skin as shown in steps 2-3. The subject would then release the plunger 2405. Finally, the subject would remove inserter 2400 from the insertion site and dispose of the inserter.
  • the sterilized inserter 2400 shown in FIGURE 59 may be utilized with driver apparatus 3900 (FIGURES 61-79) as shown in FIGURE 60.
  • driver apparatus 3900 FIGURES 61-79
  • FIGURE 60 An exemplary driver apparatus is illustrated in FIGURES 61-79 and designated driver apparatus 3900.
  • Driver apparatus 3900 includes a housing 3902 for positioning with respect to an inserter.
  • a release button 3904 longitudinally movable with respect to housing 3902— is provided. The force exerted by return spring 3906 allows release button 3904 to be moved between a proximal and distal position, as shown in FIGURES 62-65.
  • driver apparatus 3900 is positioned with respect to an inserter 2400.
  • inserter 2400 is illustrated in FIGURES 44-60, it is understood that any inserter may be used with driver apparatus 3900.
  • driver apparatus 3900 and the appropriate inserter may be modular, the dimensions of the housing 3902 and the location and shape of release button 3904 are selected to interact with the dimensions of the inserter.
  • the housing 3902 may be designed for snap-fit or friction-fit cooperation with the sheath 2402 of inserter 2400.
  • FIGURES 62-65 illustrate the sequence of motions of the driver apparatus 3900 to drive sharp 2404 into the skin of the subject.
  • FIGURE 62 illustrates driver apparatus 3900 before firing.
  • driver apparatus 3900 comprises housing 3902, release button 3904, return spring 3906, driver spring 3908, and plunger 3910.
  • Three- dimensional perspective views of housing 3902, plunger 3910, release button 3904, are depicted in FIGURES 67-69, respectively.
  • Release button 3904 comprises tabs 3912 which engage lip 3914 on housing 3902 which prevent the upward force of return spring 3906 from disengaging release button 3904 and housing 3902 (see FIGURE 66).
  • Release button 3904 also comprises protrusion 3918.
  • Plunger 3910 comprises tabs 3916 (not shown) which confine plunger 3910 to housing 3902.
  • Driver spring 3908 is disposed between the bottom of release button 3904 and the top of plunger 3910. Alternatively, the driver spring 3908 could be around the post shown of plunger 3910 and compressed by the cylinder of button 3904.
  • protrusion 3918 causes tab 3916 to become disengaged from housing 3902. This allows drive spring 3908 to advance plunger 3910 towards inserter 3900 as shown in FIGURE 64.
  • Sharp 2404 which contains sensor therein is driven into the skin of the subject and on body housing 122 is adhered to adhesive pad 118.
  • the return spring 3906 pushes it back to its initial position.
  • the arms of the button pull the arms of the plunger 3910 back to its initial position, automatically re-engaging the tabs 3916 with the housing 3902 (FIGURE 65).
  • the sensor remains inserted in the subject's skin.
  • FIGURES 70-79 An exemplary driver apparatus is illustrated in FIGURES 70-79 and designated driver apparatus 4000.
  • Driver apparatus 4000 includes a housing 4004 for positioning with respect to an inserter.
  • An outer button 4002 longitudinally movable with respect to housing 4004— is provided.
  • the force exerted by a return spring (not shown) located between housing 4004 and outer button 4002 allows outer button 3904 to be moved between a proximal and distal position, as shown in FIGURES 73-79.
  • the driver apparatus 4000 is positioned on top of inserter 2400.
  • inserter 2400 is illustrated in FIGURES 44-58, it is understood that any inserter may be used with driver apparatus 4000.
  • driver apparatus 4000 and the appropriate inserter may be modular, the dimensions of the housing 4004 and the location and shape of cam release button 3904 are selected to interact with the dimensions of the inserter.
  • the housing 4004 may be designed for snap-fit or friction- fit cooperation with the sheath of inserter 2400.
  • FIGURE 71 illustrates an exploded view of the components of driver apparatus 4000.
  • driver apparatus 4000 comprises outer button 4002, return spring 4006, inner button 4008, housing 4004, drive spring 4010, and pusher 4012.
  • the assembled driver apparatus 4000 is shown in FIGURE 72, wherein some components are partially transparent for clarity.
  • FIGURES 73-79 illustrate the sequence of motions of the driver apparatus 4000 to drive sharp 2404 into the skin of the subject.
  • FIGURE 73 illustrates driver apparatus 4000 before firing.
  • return spring 4006 is encapsulated between outer button 4002 and housing 4004.
  • drive spring 4010 is encapsulated between the bottom of inner button 4008 and surface 4020 located on plunger 4012.
  • Outer button 4002 comprises guides 4013 which lock inner button 4008 in position using tabs 4022.
  • Inner button 4008 comprises rails 4015 which allow outer button 4002 to move with respect to housing 4004.
  • Plunger 4012 comprises tabs 4014 which allow it to be fit into and retained within inner button 4008. Furthermore, plunger 4012 comprises arms 4016 having appendages 4018 with openings that engage ledge 4017 on housing 4004. [00194] To actuate driver apparatus 4000, a subject pushes down on outer button 4002 in the direction of the subject's skin causing return spring 4006 and driver spring 4010 to become compressed as illustrated in FIGURE 75. Eventually, tabs 4019 located on inner button 4008 cause appendages 4018 to be pushed off ledge 4017 as shown in FIGURE 76. [00195] The displacement of appendages 4018 from ledge allows drive spring 4010 to drive plunger 4012 towards plunger 2405 of inserter 2400 as shown in FIGURE 76.
  • sharp 2404 is driven into the skin of the subject and on body housing 122 is adhered to the subject as shown in FIGURE 77. If there is no inserter 2400 present, the plunger eventually stops its forward motion when the plunger arms engage ledge 4017 or when tabs 4014 engage inner button 4008.

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CA2766685A CA2766685A1 (en) 2010-03-24 2011-03-24 Medical device inserters and processes of inserting and using medical devices
BRPI1105769A BRPI1105769A2 (pt) 2010-03-24 2011-03-24 insersores de dispositivo médico e processos de inserção e uso de dispositivos médicos.
JP2013501503A JP2013523217A (ja) 2010-03-24 2011-03-24 医療用装置挿入器、並びに医療用装置の挿入方法および使用方法
CN201180002616.7A CN102639185B (zh) 2010-03-24 2011-03-24 医疗装置插入物以及插入和使用医疗装置的方法
AU2011269796A AU2011269796A1 (en) 2010-03-24 2011-03-24 Medical device inserters and processes of inserting and using medical devices
EP11794386A EP2552532A1 (en) 2010-03-24 2011-03-24 Medical device inserters and processes of inserting and using medical devices
IL217129A IL217129A0 (en) 2010-03-24 2011-12-21 Medical device inserters and processes of inserting and using medical devices

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11296731B2 (en) 2018-03-07 2022-04-05 Phc Holdings Corporation Communication device
US12128213B2 (en) 2020-01-30 2024-10-29 Willow Laboratories, Inc. Method of operating redundant staggered disease management systems
US12555660B2 (en) 2019-08-02 2026-02-17 Abbott Diabetes Care Inc. Systems, devices, and methods relating to medication dose guidance

Families Citing this family (337)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7381184B2 (en) 2002-11-05 2008-06-03 Abbott Diabetes Care Inc. Sensor inserter assembly
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
USD914881S1 (en) * 2003-11-05 2021-03-30 Abbott Diabetes Care Inc. Analyte sensor electronic mount
US9743862B2 (en) 2011-03-31 2017-08-29 Abbott Diabetes Care Inc. Systems and methods for transcutaneously implanting medical devices
US9572534B2 (en) 2010-06-29 2017-02-21 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
US8512243B2 (en) 2005-09-30 2013-08-20 Abbott Diabetes Care Inc. Integrated introducer and transmitter assembly and methods of use
US9398882B2 (en) 2005-09-30 2016-07-26 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor and data processing device
US7697967B2 (en) 2005-12-28 2010-04-13 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US9788771B2 (en) 2006-10-23 2017-10-17 Abbott Diabetes Care Inc. Variable speed sensor insertion devices and methods of use
US8029441B2 (en) 2006-02-28 2011-10-04 Abbott Diabetes Care Inc. Analyte sensor transmitter unit configuration for a data monitoring and management system
US9351669B2 (en) 2009-09-30 2016-05-31 Abbott Diabetes Care Inc. Interconnect for on-body analyte monitoring device
US10226207B2 (en) 2004-12-29 2019-03-12 Abbott Diabetes Care Inc. Sensor inserter having introducer
DE502005002216D1 (de) * 2005-04-08 2008-01-24 Roche Diagnostics Gmbh Vorrichtung zur Platzierung einer Sonde in lebendem Gewebe
JP2009507224A (ja) 2005-08-31 2009-02-19 ユニヴァーシティー オブ ヴァージニア パテント ファンデーション 連続グルコースセンサの精度の改善
US11298058B2 (en) 2005-12-28 2022-04-12 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
US9675290B2 (en) 2012-10-30 2017-06-13 Abbott Diabetes Care Inc. Sensitivity calibration of in vivo sensors used to measure analyte concentration
US7653425B2 (en) 2006-08-09 2010-01-26 Abbott Diabetes Care Inc. Method and system for providing calibration of an analyte sensor in an analyte monitoring system
US8219173B2 (en) 2008-09-30 2012-07-10 Abbott Diabetes Care Inc. Optimizing analyte sensor calibration
US8224415B2 (en) 2009-01-29 2012-07-17 Abbott Diabetes Care Inc. Method and device for providing offset model based calibration for analyte sensor
EP2106238A4 (en) 2006-10-26 2011-03-09 Abbott Diabetes Care Inc METHOD, SYSTEM AND COMPUTER PROGRAM PRODUCT FOR REAL-TIME DETECTION OF SENSITIVITY DECLINE IN PRODUCT DETECTORS
US8239166B2 (en) 2007-05-14 2012-08-07 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
JP5680960B2 (ja) 2007-06-21 2015-03-04 アボット ダイアベティス ケア インコーポレイテッドＡｂｂｏｔｔ Ｄｉａｂｅｔｅｓ Ｃａｒｅ Ｉｎｃ． 健康管理装置および方法
US8160900B2 (en) 2007-06-29 2012-04-17 Abbott Diabetes Care Inc. Analyte monitoring and management device and method to analyze the frequency of user interaction with the device
US8591410B2 (en) 2008-05-30 2013-11-26 Abbott Diabetes Care Inc. Method and apparatus for providing glycemic control
US8924159B2 (en) 2008-05-30 2014-12-30 Abbott Diabetes Care Inc. Method and apparatus for providing glycemic control
US9326707B2 (en) 2008-11-10 2016-05-03 Abbott Diabetes Care Inc. Alarm characterization for analyte monitoring devices and systems
US20100198034A1 (en) 2009-02-03 2010-08-05 Abbott Diabetes Care Inc. Compact On-Body Physiological Monitoring Devices and Methods Thereof
US8623041B2 (en) * 2009-02-18 2014-01-07 Panasonic Corporation Puncture tool, device for measuring biological sample and system for measuring biological sample
EP2400886A4 (en) * 2009-02-26 2014-07-02 Abbott Diabetes Care Inc IMPROVED ANALYTICAL SENSORS AND METHOD FOR THEIR MANUFACTURE AND USE
US8483967B2 (en) 2009-04-29 2013-07-09 Abbott Diabetes Care Inc. Method and system for providing real time analyte sensor calibration with retrospective backfill
US9184490B2 (en) 2009-05-29 2015-11-10 Abbott Diabetes Care Inc. Medical device antenna systems having external antenna configurations
EP3932309A1 (en) 2009-07-23 2022-01-05 Abbott Diabetes Care, Inc. Continuous analyte measurement system
WO2011014851A1 (en) 2009-07-31 2011-02-03 Abbott Diabetes Care Inc. Method and apparatus for providing analyte monitoring system calibration accuracy
EP2473098A4 (en) 2009-08-31 2014-04-09 Abbott Diabetes Care Inc ANALYTICAL SIGNAL PROCESSING APPARATUS AND METHOD
ES2950160T3 (es) 2009-08-31 2023-10-05 Abbott Diabetes Care Inc Visualizadores para un dispositivo médico
EP2473963A4 (en) 2009-08-31 2014-01-08 Abbott Diabetes Care Inc MEDICAL DEVICES AND METHOD
EP2335565A1 (de) 2009-12-18 2011-06-22 Roche Diagnostics GmbH Schutzbehälter für Aufnahme wieder verwendbarer diagnostischer Komponenten
USD924406S1 (en) 2010-02-01 2021-07-06 Abbott Diabetes Care Inc. Analyte sensor inserter
EP4248866A3 (en) 2010-03-24 2023-12-20 Abbott Diabetes Care, Inc. Medical device inserters
WO2011149857A1 (en) 2010-05-24 2011-12-01 Abbott Diabetes Care Inc. Method and system for updating a medical device
US11064921B2 (en) 2010-06-29 2021-07-20 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
US10092229B2 (en) 2010-06-29 2018-10-09 Abbott Diabetes Care Inc. Calibration of analyte measurement system
JP5748595B2 (ja) * 2010-08-30 2015-07-15 アークレイ株式会社 センサ挿入・回収装置
CA3175799A1 (en) * 2011-02-09 2012-08-16 Becton, Dickinson And Company Subcutaneous infusion device
US9760679B2 (en) 2011-02-11 2017-09-12 Abbott Diabetes Care Inc. Data synchronization between two or more analyte detecting devices in a database
US20140088392A1 (en) 2011-02-11 2014-03-27 Abbott Diabetes Care Inc. Feedback from Cloud or HCP to Payer or Patient via Meter or Cell Phone
WO2012108938A1 (en) 2011-02-11 2012-08-16 Abbott Diabetes Care Inc. Software applications residing on handheld analyte determining devices
USD694397S1 (en) * 2011-02-28 2013-11-26 Abbott Diabetes Care Inc. Medical device inserter
CN107019515B (zh) 2011-02-28 2021-02-26 雅培糖尿病护理公司 显示传感器读数的方法与分析物监测装置及其操作方法
US10136845B2 (en) 2011-02-28 2018-11-27 Abbott Diabetes Care Inc. Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same
WO2012127279A1 (en) * 2011-03-18 2012-09-27 Nokia Corporation Switching cells on and off on a need basis in a wireless communications system
ES2847578T3 (es) 2011-04-15 2021-08-03 Dexcom Inc Calibración avanzada de sensor de analito y detección de errores
USD691710S1 (en) * 2011-05-23 2013-10-15 Abbott Diabetes Care Inc. Medical device inserter
DK2720610T3 (da) 2011-06-17 2025-09-15 Abbott Diabetes Care Inc Stablet analytsensor med en første elektrode der er smallere end sensorens anden elektrode
US9615759B2 (en) * 2011-07-12 2017-04-11 Bard Access Systems, Inc. Devices and methods for ECG guided vascular access
US9949677B2 (en) * 2011-10-21 2018-04-24 Incube Labs, Llc Implantable oximetric measurement apparatus and method of use
WO2013066849A1 (en) 2011-10-31 2013-05-10 Abbott Diabetes Care Inc. Model based variable risk false glucose threshold alarm prevention mechanism
DK3831283T3 (da) * 2011-12-11 2023-05-30 Abbott Diabetes Care Inc Analytsensorindretninger, forbindelser og fremgangsmåder
EP2825237B1 (en) * 2012-03-15 2020-06-10 Fisher & Paykel Healthcare Limited Respiratory gas humidification system
US20130267812A1 (en) * 2012-04-04 2013-10-10 Dexcom, Inc. Transcutaneous analyte sensors, applicators therefor, and associated methods
EP2650031A1 (en) * 2012-04-11 2013-10-16 PharmaSens AG Manual pressure activated application mechanism
EP4541272A3 (en) 2012-04-24 2025-05-07 Abbott Diabetes Care, Inc. Methods of lag-compensation for analyte measurements, and devices related thereto
GB2575895B (en) 2012-04-27 2020-06-03 Fisher & Paykel Healthcare Ltd Humidification apparatus including a port cap
US9504828B2 (en) 2012-07-26 2016-11-29 Nyxoah SA Electrical contacts on a medical device patch
US9907967B2 (en) 2012-07-26 2018-03-06 Adi Mashiach Transcutaneous power conveyance device
WO2014016694A2 (en) 2012-07-26 2014-01-30 Adi Mashiach Internal resonance matching between an implanted device and an external device
US9968306B2 (en) * 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
US9907492B2 (en) 2012-09-26 2018-03-06 Abbott Diabetes Care Inc. Method and apparatus for improving lag correction during in vivo measurement of analyte concentration with analyte concentration variability and range data
WO2014049886A1 (ja) * 2012-09-28 2014-04-03 テルモ株式会社 穿刺装置及び薬液投与装置
TWI533899B (zh) * 2012-11-02 2016-05-21 da-lun Tan A fixed-treating apparatus for the othematoma
US9211092B2 (en) 2013-01-03 2015-12-15 Dexcom, Inc. End of life detection for analyte sensors
US10888662B2 (en) 2013-01-15 2021-01-12 Sanofi-Aventis Deutschland Gmbh Apparatus for recording information concerning the use of an injection device
USD732162S1 (en) * 2013-03-14 2015-06-16 Eli Lilly And Company Automatic injection device
US10076285B2 (en) 2013-03-15 2018-09-18 Abbott Diabetes Care Inc. Sensor fault detection using analyte sensor data pattern comparison
US10433773B1 (en) 2013-03-15 2019-10-08 Abbott Diabetes Care Inc. Noise rejection methods and apparatus for sparsely sampled analyte sensor data
US9474475B1 (en) 2013-03-15 2016-10-25 Abbott Diabetes Care Inc. Multi-rate analyte sensor data collection with sample rate configurable signal processing
CN105377118B (zh) 2013-03-15 2019-09-17 雅培糖尿病护理公司 与分析物监视设备相关联的设备、系统和方法以及包含其的设备
ES2662110T3 (es) * 2013-04-15 2018-04-05 Becton, Dickinson And Company Dispositivo de transferencia de muestras de fluidos biológicos y sistema de separación y de análisis de fluidos biológicos
CA3005826C (en) 2013-04-15 2021-11-23 Becton, Dickinson And Company Biological fluid collection device and biological fluid separation and testing system
DE202014011590U1 (de) 2013-04-30 2023-01-10 Abbott Diabetes Care, Inc. Systeme und Vorrichtungen zur energieeffizienten Aktivierung elektrischer Vorrichtungen
US10398881B2 (en) 2013-08-03 2019-09-03 Merit Medical Systems, Inc. Inflation devices with remote displays, methods and kits related thereto
US10046144B2 (en) 2013-08-03 2018-08-14 Merit Medical Systems, Inc. Methods of resetting inflation devices
GB2580554B (en) 2013-09-13 2020-12-30 Fisher & Paykel Healthcare Ltd Connections for humidification system
EP4442299A3 (en) * 2013-09-30 2025-08-13 Medimop Medical Projects Ltd Stabilized pen injector
WO2015069563A1 (en) 2013-11-05 2015-05-14 Abbott Diabetes Care Inc. Systems, devices, and methods for control of a power supply connection
EP3073919B1 (en) 2013-11-27 2019-05-08 Abbott Diabetes Care Inc. Systems and methods for revising permanent rom-based programming
CN103705217A (zh) * 2013-12-20 2014-04-09 深圳中科讯联科技有限公司 一种基于射频sim卡的人体健康监测装置及方法
DE202014011530U1 (de) 2013-12-27 2021-12-17 Abbott Diabetes Care, Inc. Systeme und Vorrichtungen zur Authentifizierung in einer Analytüberwachungsumgebung
EP4404210A3 (en) 2013-12-27 2024-10-16 Abbott Diabetes Care Inc. Application interface and display control in an analyte monitoring environment
CN105899132B (zh) 2013-12-31 2020-02-18 雅培糖尿病护理公司 自供电分析物传感器以及使用其的装置
WO2015119515A1 (en) 2014-02-07 2015-08-13 Fisher & Paykel Healthcare Limited Respiratory humidification system
WO2015122964A1 (en) 2014-02-11 2015-08-20 Dexcom, Inc. Packaging system for analyte sensors
JP6332786B2 (ja) * 2014-02-14 2018-05-30 株式会社ライトニックス 医療用針および穿刺具
EP3110606B1 (en) * 2014-02-24 2021-09-15 Sony Group Corporation Smart wearable devices and methods for automatically configuring capabilities with biology and environment capture sensors
US10034976B2 (en) * 2014-03-24 2018-07-31 Medtronic Minimed, Inc. Fluid infusion patch pump device with automatic fluid system priming feature
US20170185748A1 (en) 2014-03-30 2017-06-29 Abbott Diabetes Care Inc. Method and Apparatus for Determining Meal Start and Peak Events in Analyte Monitoring Systems
US10327679B2 (en) * 2014-09-03 2019-06-25 Nova Biomedical Corporation Subcutaneous sensor inserter and method
TWM496457U (zh) * 2014-09-11 2015-03-01 Biotest Medical Corp 具針座引導結構之採血裝置
WO2016065190A1 (en) 2014-10-23 2016-04-28 Abbott Diabetes Care Inc. Electrodes having at least one sensing structure and methods for making and using the same
US10772556B2 (en) 2014-11-05 2020-09-15 Cláudio Afonso Ambrósio Method and system for monitoring and treating hypoglycemia
AU2015349931B2 (en) 2014-11-19 2020-08-13 Abbott Diabetes Care Inc. Systems, devices, and methods for revising or supplementing ROM-based RF commands
JP6618486B2 (ja) 2015-01-27 2019-12-11 テルモ株式会社 センサ挿入装置及びセンサ挿入装置セット
US9345833B1 (en) 2015-02-11 2016-05-24 King Saud University Dental instrument
US10251605B2 (en) 2015-02-16 2019-04-09 Verily Life Sciences Llc Bandage type of continuous glucose monitoring system
WO2016141123A1 (en) 2015-03-04 2016-09-09 Merit Medical Systems, Inc. Pull tab assemblies and related methods
CN107205702B (zh) * 2015-03-11 2020-05-01 泰尔茂株式会社 传感器插入装置以及更换件
WO2016153313A1 (en) * 2015-03-25 2016-09-29 Samsung Electronics Co., Ltd. Wearable electronic device
US10213139B2 (en) 2015-05-14 2019-02-26 Abbott Diabetes Care Inc. Systems, devices, and methods for assembling an applicator and sensor control device
CA2984939A1 (en) * 2015-05-14 2016-11-17 Abbott Diabetes Care Inc. Compact medical device inserters and related systems and methods
US20160338628A1 (en) * 2015-05-22 2016-11-24 Dexcom, Inc. Needle for transcutaneous analyte sensor delivery
PL3097933T3 (pl) 2015-05-26 2020-03-31 F. Hoffmann-La Roche Ag Kaseta i urządzenie wprowadzające dla układu medycznego
US10292630B2 (en) 2015-06-01 2019-05-21 Verily Life Sciences Llc Optical sensor for bandage type monitoring device
USD794801S1 (en) 2015-07-09 2017-08-15 Dexcom, Inc. Base for medical device electronic module
USD794800S1 (en) * 2015-07-09 2017-08-15 Dexcom, Inc. Medical device inserter
USD794201S1 (en) 2015-07-09 2017-08-08 Dexcom, Inc. Medical device electronic module
US20170112534A1 (en) 2015-10-21 2017-04-27 Dexcom, Inc. Transcutaneous analyte sensors, applicators therefor, and associated methods
USD878575S1 (en) * 2015-11-24 2020-03-17 Visionisti Oy Hand operated medical instrument
EP3804611B1 (en) 2015-12-30 2024-07-17 Dexcom, Inc. Transcutaneous analyte sensor systems and methods
EP3195891B1 (en) * 2016-01-25 2021-10-06 Roche Diabetes Care GmbH Medical device and process for manufacturing
DK3199121T3 (en) * 2016-01-29 2018-12-10 Hoffmann La Roche FUNCTIONAL MEDICAL PACKAGING AND MEDICAL DEVICE FOR INSTALLING AT LEAST ONE SUB-SYSTEM IN A HOST
WO2017130559A1 (ja) * 2016-01-29 2017-08-03 テルモ株式会社 生体情報検出装置
RS65949B1 (sr) 2016-02-05 2024-10-31 Hoffmann La Roche Medicinski uređaj za detekciju najmanje jednog analita u telesnoj tečnosti
DE202016009189U1 (de) 2016-02-05 2023-08-25 Roche Diabetes Care Gmbh Medizinische Vorrichtung zum Nachweis mindestens eines Analyten in einer Körperflüssigkeit
DE202016009188U1 (de) 2016-02-05 2023-08-30 Roche Diabetes Care Gmbh Medizinische Vorrichtung zum Nachweis mindestens eines Analyten in einer Körperflüssigkeit
DE202016009190U1 (de) 2016-02-05 2023-08-23 Roche Diabetes Care Gmbh Medizinische Vorrichtung zum Nachweis mindestens eines Analyten in einer Körperflüssigkeit
RS66282B1 (sr) * 2016-02-05 2025-01-31 Hoffmann La Roche Medicinski uređaj za detekciju najmanje jednog analita u telesnoj tečnosti
EP3207870A1 (en) 2016-02-16 2017-08-23 Roche Diabetes Care GmbH Body-mountable device, medical sensor assembly and method of use
US11432750B2 (en) 2016-03-14 2022-09-06 Abbott Diabetes Care Inc. In vivo enzyme activity sensors and methods
US9827369B2 (en) * 2016-03-16 2017-11-28 Baxter International Inc. Percutaneous administration device and method for injecting medicinal substances
EP3435865B1 (en) 2016-03-29 2024-10-23 Roche Diabetes Care GmbH Method of operating a receiver for receiving analyte data, receiver and computer program product
US10118696B1 (en) 2016-03-31 2018-11-06 Steven M. Hoffberg Steerable rotating projectile
US12419547B2 (en) 2016-04-08 2025-09-23 Medtronic Minimed, Inc. Sensor and transmitter product
US20170290535A1 (en) * 2016-04-08 2017-10-12 Medtronic Minimed, Inc. Analyte sensor with indicators
US20230027522A1 (en) * 2016-04-08 2023-01-26 Medtronic Minimed, Inc. Insertion device
US10765369B2 (en) 2016-04-08 2020-09-08 Medtronic Minimed, Inc. Analyte sensor
WO2017211493A1 (en) * 2016-06-10 2017-12-14 Fresenius Kabi Deutschland Gmbh Cannulation device
JP7059251B2 (ja) 2016-08-01 2022-04-25 ウェスト ファーマ サービシーズ イスラエル リミテッド ドアの半閉じを防止するスプリング
CN106236140B (zh) * 2016-08-25 2019-11-08 成都优途科技有限公司 一种超声成像方法、装置及系统
CN112515668A (zh) * 2016-09-21 2021-03-19 威里利生命科学有限责任公司 用于激活植入设备的电路的系统和方法
KR101863451B1 (ko) * 2016-10-07 2018-06-11 조효진 일회용 인슐린 주입 기구
EP4063811A1 (en) 2016-12-07 2022-09-28 Fisher & Paykel Healthcare Limited Seal/cover for use with a sensing arrangement of a medical device
US20180172664A1 (en) * 2016-12-20 2018-06-21 Abbott Diabetes Care Inc. Systems, devices, and methods for wireless communications in analyte monitoring systems
US10334515B2 (en) 2017-01-13 2019-06-25 ENK Wireless, Inc. Conveying information via auxiliary device selection
WO2018136898A1 (en) 2017-01-23 2018-07-26 Abbott Diabetes Care Inc. Systems, devices and methods for analyte sensor insertion
WO2018152146A1 (en) * 2017-02-14 2018-08-23 Verily Life Sciences Llc Needle alignment for wearable biosensors
EP3586145A1 (en) 2017-02-21 2020-01-01 Abbott Diabetes Care Inc. Methods, devices, and systems for physiological parameter analysis
WO2018160591A1 (en) * 2017-03-02 2018-09-07 Abbott Diabetes Care Inc. Systems, devices, and methods utilizing secondary communication systems
MX2019012330A (es) * 2017-04-19 2020-01-23 Metronom Health Inc Insertador para sensores de analitos.
EP3618712A1 (en) 2017-05-03 2020-03-11 Abbott Diabetes Care Inc. Systems, devices, and methods with duration-based adjustment of sensor data
US11806134B2 (en) 2017-05-09 2023-11-07 Ascensia Diabetes Care Holdings Ag Sensor assembly apparatus and methods for continuous glucose monitors
CN107015000B (zh) * 2017-05-27 2018-10-12 北京怡唐生物科技有限公司 动态连续血糖监测系统的一次性监测装置
CN110869072B (zh) 2017-05-30 2021-12-10 西部制药服务有限公司(以色列) 用于穿戴式注射器的模块化驱动机构
WO2018222015A1 (ko) * 2017-06-02 2018-12-06 주식회사 아이센스 연속 혈당 측정기용 센서 어플리케이터 조립체
WO2018222013A1 (ko) * 2017-06-02 2018-12-06 주식회사 아이센스 연속 혈당 측정기용 센서 어플리케이터 조립체
JP7061627B2 (ja) * 2017-06-02 2022-04-28 アイセンス，インコーポレーテッド 連続血糖測定器用センサーアプリケーター組立体
WO2018222012A1 (ko) * 2017-06-02 2018-12-06 주식회사 아이센스 연속 혈당 측정기용 센서 어플리케이터 조립체
WO2018222010A1 (ko) * 2017-06-02 2018-12-06 주식회사 아이센스 연속 혈당 측정기용 센서 어플리케이터 조립체
WO2018222016A1 (ko) * 2017-06-02 2018-12-06 주식회사 아이센스 연속 혈당 측정기용 센서 어플리케이터 조립체
WO2018222014A1 (ko) * 2017-06-02 2018-12-06 주식회사 아이센스 연속 혈당 측정기용 센서 어플리케이터 조립체
WO2018222009A1 (ko) * 2017-06-02 2018-12-06 주식회사 아이센스 연속 혈당 측정기용 센서 어플리케이터 조립체
WO2018222011A1 (ko) * 2017-06-02 2018-12-06 주식회사 아이센스 연속 혈당 측정기용 센서 어플리케이터 조립체
EP4647086A3 (en) * 2017-06-19 2025-12-31 DexCom, Inc. APPLICATORS DESIGNED FOR APPLYING TRANSCUTANEOUS ANALYTE SENSORS
US10863944B2 (en) * 2017-06-23 2020-12-15 Dexcom, Inc. Transcutaneous analyte sensors, applicators therefor, and associated methods
US20190000360A1 (en) 2017-06-29 2019-01-03 Abbott Diabetes Care Inc. Systems, devices, and methods for establishing and/or maintaining synchronization between entities in an analyte monitoring environment
US20190015827A1 (en) 2017-07-17 2019-01-17 Tasso, Inc. Apparatus, Systems And Methods For Preparing And Shipping Samples
US11331019B2 (en) 2017-08-07 2022-05-17 The Research Foundation For The State University Of New York Nanoparticle sensor having a nanofibrous membrane scaffold
FI3668400T3 (fi) 2017-08-18 2023-08-29 Abbott Diabetes Care Inc Menetelmä analyyttianturien yksilölliseen kalibrointiin
WO2019054113A1 (ja) * 2017-09-14 2019-03-21 テルモ株式会社 挿入装置及び検出装置
WO2019083939A1 (en) 2017-10-24 2019-05-02 Dexcom, Inc. PRECONNECTED ANALYTE SENSORS
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
US11918348B2 (en) 2017-12-05 2024-03-05 Abbott Diabetes Care Inc. Medical devices having a dynamic surface profile and methods for production and use thereof
US11311212B2 (en) 2017-12-05 2022-04-26 Abbott Diabetes Care Inc. Guard rings for on-body analyte sensors
RS66567B1 (sr) 2017-12-21 2025-03-31 Hoffmann La Roche Medicinski sistem i postupak za njegovu proizvodnju
JP2019115400A (ja) * 2017-12-26 2019-07-18 テルモ株式会社 生体情報検出装置、及び、ベース部材
US11073838B2 (en) 2018-01-06 2021-07-27 Drivent Llc Self-driving vehicle systems and methods
US10299216B1 (en) * 2018-01-06 2019-05-21 Eric John Wengreen Self-driving vehicle actions in response to a low battery
DE102018101283A1 (de) * 2018-01-22 2019-07-25 Eyesense Gmbh Injektor zum transkutanen Einführen eines Sensors in einen Patienten
DE102018101275A1 (de) 2018-01-22 2019-07-25 Eyesense Gmbh Injektor zum transkutanen Einführen eines Sensors in einen Patienten
CN111971982A (zh) 2018-02-05 2020-11-20 雅培糖尿病护理公司 用于电子装置之间的节能无线通信的系统、装置和方法
WO2019176324A1 (ja) * 2018-03-13 2019-09-19 Ｐｈｃホールディングス株式会社 センサ挿入装置
US11712637B1 (en) 2018-03-23 2023-08-01 Steven M. Hoffberg Steerable disk or ball
JP6853413B2 (ja) * 2018-03-23 2021-03-31 Ｐｈｃホールディングス株式会社 センサ挿入装置
EP3784120A4 (en) 2018-04-26 2022-02-16 Merit Medical Systems, Inc. PROXIMITY COUPLING INFLATORS, METHODS AND RELATED SYSTEMS THEREOF
CA3092649A1 (en) * 2018-05-04 2019-11-07 Dexcom, Inc. Systems and methods for power management in analyte sensor system
US20210236028A1 (en) 2018-05-17 2021-08-05 Abbott Diabetes Care Inc. Analyte sensor antimicrobial configurations and adhesives
EP4218567B1 (en) * 2018-06-07 2025-03-12 Abbott Diabetes Care, Inc. Focused sterilization and sterilized sub-assemblies for analyte monitoring systems
CN119924827A (zh) * 2018-06-07 2025-05-06 雅培糖尿病护理公司 用于分析物监测系统的聚焦灭菌和已灭菌的子组件
USD888252S1 (en) 2018-06-18 2020-06-23 Dexcom, Inc. Transcutaneous analyte sensor applicator
USD926325S1 (en) 2018-06-22 2021-07-27 Dexcom, Inc. Wearable medical monitoring device
WO2020027420A1 (ko) * 2018-07-31 2020-02-06 주식회사 아이센스 연속 혈당 측정 장치
KR102200136B1 (ko) * 2018-07-31 2021-01-11 주식회사 아이센스 연속 혈당 측정 장치
WO2020027421A1 (ko) * 2018-07-31 2020-02-06 주식회사 아이센스 연속 혈당 측정용 신체 부착 유닛
KR102200138B1 (ko) * 2018-07-31 2021-01-11 주식회사 아이센스 연속 혈당 측정 장치
KR102185137B1 (ko) 2018-07-31 2020-12-02 주식회사 아이센스 연속 혈당 측정용 신체 부착 유닛
WO2020027422A1 (ko) * 2018-07-31 2020-02-06 주식회사 아이센스 연속 혈당 측정용 신체 부착 유닛
KR102185833B1 (ko) * 2018-07-31 2020-12-03 주식회사 아이센스 연속 혈당 측정 장치
KR102200140B1 (ko) 2018-07-31 2021-01-11 주식회사 아이센스 연속 혈당 측정용 신체 부착 유닛
KR102197578B1 (ko) * 2018-07-31 2021-01-05 주식회사 아이센스 연속 혈당 측정용 신체 부착 유닛
KR102197577B1 (ko) * 2018-07-31 2021-01-05 주식회사 아이센스 연속 혈당 측정 장치
KR102222045B1 (ko) * 2018-07-31 2021-03-04 주식회사 아이센스 연속 혈당 측정 장치
KR102200137B1 (ko) * 2018-07-31 2021-01-11 주식회사 아이센스 연속 혈당 측정용 신체 부착 유닛
KR102200139B1 (ko) 2018-08-07 2021-01-08 주식회사 아이센스 연속혈당측정기의 동작 제어 장치
CN112638254B (zh) 2018-08-23 2024-10-15 雅培糖尿病护理股份有限公司 包含定向穿刺针的针组件及其制造方法
EP3847964B1 (en) * 2018-09-05 2023-09-27 PHC Holdings Corporation Biological information measurement device
KR102200142B1 (ko) * 2018-09-27 2021-01-11 주식회사 아이센스 연속 혈당 측정용 신체 부착 유닛
KR102200141B1 (ko) * 2018-09-27 2021-01-11 주식회사 아이센스 연속 혈당 측정용 신체 부착 유닛
US11221622B2 (en) 2019-03-21 2022-01-11 Drivent Llc Self-driving vehicle systems and methods
US11644833B2 (en) 2018-10-01 2023-05-09 Drivent Llc Self-driving vehicle systems and methods
CN112888361B (zh) 2018-10-12 2024-12-10 雅培糖尿病护理公司 用于传感器故障检测的系统、装置和方法
CN109938707A (zh) * 2018-10-16 2019-06-28 陕西医链区块链集团有限公司 一种能够植入人体监测生命健康安全的智能芯片
JP7254916B2 (ja) 2018-10-26 2023-04-10 アボット ダイアベティス ケア インコーポレイテッド 生理学的パラメータ分析のための方法、デバイスおよびシステム
JP2022507378A (ja) * 2018-11-13 2022-01-18 タッソ インコーポレイテッド 電子機器を含む体液収集デバイスならびに関連するシステムおよび方法
US10940554B2 (en) * 2018-11-30 2021-03-09 International Business Machines Corporation Planar fabrication of micro-needles
EP3899513B1 (en) 2018-12-19 2025-09-03 Abbott Diabetes Care Inc. Systems, devices, and methods for rf detection of analyte sensor measurements
US12521041B2 (en) * 2018-12-21 2026-01-13 Abbott Diabetes Care Inc. Systems, devices, and methods for analyte sensor insertion
US12539361B2 (en) 2019-02-22 2026-02-03 Deka Products Limited Partnership Infusion set and inserter assembly apparatuses, systems, and methods
EP4643905A3 (en) 2019-02-22 2026-01-21 DEKA Products Limited Partnership Inserter assembly for infusion sets
US12156734B2 (en) 2019-03-20 2024-12-03 Phc Holdings Corporation Sensor insertion device
WO2020214984A1 (en) 2019-04-18 2020-10-22 Abbott Diabetes Care Inc. Systems, devices, and methods for handling wireless communications in an analyte monitoring environment
US11317867B2 (en) 2019-04-23 2022-05-03 Medtronic Minimed, Inc. Flexible physiological characteristic sensor assembly
US11224361B2 (en) * 2019-04-23 2022-01-18 Medtronic Minimed, Inc. Flexible physiological characteristic sensor assembly
KR102237092B1 (ko) * 2019-04-30 2021-04-13 주식회사 아이센스 연속 혈당 측정 장치용 어플리케이터
CN109924952B (zh) * 2019-04-30 2025-04-29 三诺生物传感股份有限公司 一种植入工具推针结构和植入式传感器用植入工具
CA3138101C (en) * 2019-05-14 2024-06-11 Sanvita Medical Corporation Subcutaneous analyte sensor applicator and continuous monitoring system
USD1002852S1 (en) 2019-06-06 2023-10-24 Abbott Diabetes Care Inc. Analyte sensor device
IT201900008208A1 (it) * 2019-06-06 2020-12-06 Emtesys S R L Sistema e metodo per applicazioni di telediabetologia
GB201909176D0 (en) * 2019-06-26 2019-08-07 Royal College Of Art Wearable device
CN110338888B (zh) * 2019-07-18 2024-05-07 浙江荷清柔性电子技术有限公司 植入施加器
US12193809B2 (en) 2019-08-02 2025-01-14 Bionime Corporation Physiological signal monitoring device
TWI729670B (zh) 2019-08-02 2021-06-01 華廣生技股份有限公司 生物感測器之植入裝置
US11896804B2 (en) 2019-08-02 2024-02-13 Bionime Corporation Insertion device for a biosensor and insertion method thereof
US12343172B2 (en) 2019-08-02 2025-07-01 Bionime Corporation Insertion device for a biosensor
US12023150B2 (en) * 2019-08-02 2024-07-02 Bionime Corporation Implantable micro-biosensor
US11678846B2 (en) 2019-08-02 2023-06-20 Bionime Corporation Insertion device for a biosensor
WO2021024125A1 (en) * 2019-08-02 2021-02-11 Bionime Corporation Physiological signal monitoring device
US11737689B2 (en) 2019-08-02 2023-08-29 Bionime Corporation Physiological signal monitoring device
EP3771425A1 (en) 2019-08-02 2021-02-03 Bionime Corporation Insertion device for a biosensor and insertion method thereof
EP3771451B1 (en) 2019-08-02 2025-10-08 Bionime Corporation A container for carrying a sensor
US12403260B2 (en) * 2019-08-02 2025-09-02 Bionime Corporation Insertion device for a biosensor and insertion method thereof
KR102238431B1 (ko) * 2019-08-07 2021-04-12 주식회사 아이센스 연속 혈당 측정 장치용 삽입 가이드 니들
KR102238432B1 (ko) * 2019-08-07 2021-04-12 주식회사 아이센스 연속 혈당 측정 장치용 삽입 가이드 니들 제작 방법
US11707297B2 (en) 2019-08-20 2023-07-25 Ascensia Diabetes Care Holdings Ag Continuous analyte monitor inserter apparatus and methods
US11602373B2 (en) 2019-08-20 2023-03-14 Ascensia Diabetes Care Holdings Ag Biosensor inserter apparatus and methods
CN114630619A (zh) * 2019-08-30 2022-06-14 塔索公司 体液收集装置及相关方法
CN115153527B (zh) * 2019-08-31 2025-04-15 深圳硅基传感科技有限公司 推送装置
CN116649965B (zh) * 2019-08-31 2025-11-18 深圳硅基传感科技有限公司 具有偏置件的推送装置
AU2020341482A1 (en) * 2019-09-03 2022-04-14 Metronom Health, Inc. Analyte sensor applicator
CN114916219A (zh) 2019-10-28 2022-08-16 雅培糖尿病护理公司 用于传感器通信的系统、装置和方法
US12147229B2 (en) 2019-11-08 2024-11-19 Drivent Llc Self-driving vehicle systems and methods
JP2023502534A (ja) 2019-11-25 2023-01-24 アボット ダイアベティス ケア インコーポレイテッド 生理学的パラメータ分析のための方法、デバイス及びシステム
CN115023764A (zh) 2019-11-25 2022-09-06 雅培糖尿病护理公司 用于调整实验室hba1c值的方法、设备和系统
EP3861934A1 (fr) * 2020-02-05 2021-08-11 PKvitality Dispositif de mesure d'analyte comprenant un patch adhesif
EP4106627A4 (en) * 2020-02-20 2024-05-01 Medtrum Technologies Inc. Highly integrated analyte detection device
KR102331552B1 (ko) * 2020-03-03 2021-11-29 주식회사 아이센스 연속 혈당 측정 장치
DE102020110691A1 (de) * 2020-04-20 2021-10-21 KROMA INTERNATIONAL GmbH Verfahren zum Herstellen einer Vorrichtung zum Behandeln einer Oberfläche
US12539414B2 (en) 2020-05-20 2026-02-03 Tc1 Llc Systems and methods for blood pump connectors
US12213782B2 (en) * 2020-06-04 2025-02-04 Medtronic Minimed, Inc. Physiological characteristic sensor system
US12551105B2 (en) 2020-06-08 2026-02-17 Abbott Diabetes Care Inc. Systems, devices, and methods for improved analyte sensor accuracy and fault detection
US12465251B2 (en) 2020-07-08 2025-11-11 Abbott Diabetes Care Inc. Analyte sensors featuring enhancements for decreasing interferent signal
WO2022011167A1 (en) 2020-07-10 2022-01-13 Abbott Diabetes Care Inc. Systems and methods for background signal reduction in biosensors
TWI780828B (zh) * 2020-07-23 2022-10-11 仁寶電腦工業股份有限公司 穿刺裝置及採血裝置
US20230301556A1 (en) * 2020-08-26 2023-09-28 Tingo Medical Ltd. Continuous glucose sensor and mounting assembly
USD948723S1 (en) * 2020-08-27 2022-04-12 Medtrum Technologies Inc. Installer for body fluid analyte detection device
US12239463B2 (en) 2020-08-31 2025-03-04 Abbott Diabetes Care Inc. Systems, devices, and methods for analyte sensor insertion
AU2021332055A1 (en) * 2020-08-31 2023-02-23 Abbott Diabetes Care Inc. Systems, devices, and methods for analyte sensor applicators
EP4503883A3 (en) * 2020-09-07 2025-07-30 Ascensia Diabetes Care Holdings AG Methods and apparatus enabling coupling of an electronics unit to a base unit of a continuous analyte monitoring device
CA3186905A1 (en) 2020-09-15 2022-03-24 Abbott Diabetes Care Inc. Systems, devices, and methods for an analyte sensor
US12569168B2 (en) 2020-09-15 2026-03-10 Abbott Diabetes Care Inc. Systems, devices, and methods for analyte monitoring
WO2022076651A1 (en) * 2020-10-08 2022-04-14 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Device for measurement of core body temperature and temperature monitoring methods
CN114343624B (zh) 2020-10-14 2025-09-12 华广生技股份有限公司 植针结构及植入装置
EP4258990A2 (en) 2020-12-10 2023-10-18 Abbott Diabetes Care Inc. Systems, devices, and methods for analyte sensor insertion
USD999913S1 (en) 2020-12-21 2023-09-26 Abbott Diabetes Care Inc Analyte sensor inserter
AU2021410547B2 (en) 2020-12-23 2025-12-18 Abbott Diabetes Care Inc. Analyte sensors with reduced interferent signal and methods
EP4271271A4 (en) 2020-12-31 2025-02-26 Abbott Diabetes Care, Inc. EMBEDDED SYSTEMS IN MEDICAL MONITORING SYSTEMS
WO2022147985A1 (en) * 2021-01-05 2022-07-14 Medtrum Technologies Inc. A skin patch drug infusion device
US11944786B2 (en) * 2021-01-18 2024-04-02 Medtronic Minimed, Inc. Infusion device
JP7674492B2 (ja) 2021-01-21 2025-05-09 アセンシア・ダイアベティス・ケア・ホールディングス・アーゲー 医療廃棄物を低減したバイオセンサーインサータ
JP2024504677A (ja) 2021-01-21 2024-02-01 アセンシア・ダイアベティス・ケア・ホールディングス・アーゲー ウェアラブルな連続的な分析物測定デバイス、バイオセンサ挿入器、及び使用方法
CN117042687A (zh) * 2021-01-26 2023-11-10 美国雅培糖尿病护理公司 涉及酮传感器的系统、装置和方法
WO2022169856A1 (en) 2021-02-03 2022-08-11 Abbott Diabetes Care Inc. Systems, devices, and methods relating to medication dose guidance
KR102557857B1 (ko) * 2021-03-04 2023-07-24 주식회사 아이센스 연속 혈당 측정장치용 어플리케이터
CN113082362B (zh) * 2021-03-26 2022-09-20 普昂(杭州)健康管理有限公司 一种分体式敷贴皮下软针及穿刺方法
USD985774S1 (en) * 2021-03-30 2023-05-09 Ascensia Diabetes Care Holdings Ag Aanalyte monitoring device
WO2022226077A1 (en) 2021-04-21 2022-10-27 Abbott Diabetes Care Inc. Systems and methods for diabetes management
KR102592776B1 (ko) * 2021-06-29 2023-10-25 주식회사 아이센스 경피성 센서를 삽입하기 위한 니들 및 니들 어셈블리
AU2022310377A1 (en) * 2021-07-16 2024-01-04 Abbott Diabetes Care Inc. Systems, devices, and methods for analyte monitoring
CN117729888A (zh) * 2021-07-27 2024-03-19 恩格医疗公司 用于保持可穿戴监测设备的保持设备
EP4434501A3 (en) * 2021-08-19 2024-10-16 Roche Diabetes Care GmbH Analyte monitoring system and device comprising a body part that is attachable to a body of a patient
KR102614603B1 (ko) * 2021-09-01 2023-12-19 주식회사 아이센스 신체 부착 디바이스용 보호 시트 및 이를 포함하는 신체 부착 디바이스
EP4408281A4 (en) * 2021-09-27 2025-06-04 Medtrum Technologies Inc. INSTALLATION UNIT FOR AN ANALYTE DETECTION DEVICE
CN115868973B (zh) * 2021-09-27 2025-12-23 上海移宇科技有限公司 分析物检测装置安装单元
WO2023044890A1 (en) * 2021-09-27 2023-03-30 Medtrum Technologies Inc. Installation unit of analyte detection device
EP4408277A4 (en) * 2021-09-27 2025-06-04 Medtrum Technologies Inc. INSTALLATION UNIT FOR AN ANALYTE DETECTION DEVICE
WO2023055755A1 (en) 2021-09-28 2023-04-06 Biolinq Incorporated Microneedle enclosure and applicator device for microneedle array based continuous analyte monitoring device
CN115868974B (zh) * 2021-09-29 2025-09-09 上海微创生命科技有限公司 医疗设备及医疗辅助装置
DE112022005310T5 (de) 2021-11-05 2024-09-05 Abbott Diabetes Care, Inc. Verfahren, vorrichtungen und systeme zum anpassen von labor-hba1c-werten
CN114099848B (zh) * 2021-11-26 2025-09-12 泰州市人民医院 防针刺伤定位型输液港穿刺针装置
CN116195994A (zh) * 2021-11-30 2023-06-02 上海微创生命科技有限公司 灭菌盒组件、植入器及植入系统
USD1033641S1 (en) 2021-12-17 2024-07-02 Biolinq Incorporated Microneedle array sensor applicator device
AU2023205852A1 (en) * 2022-01-04 2024-06-27 Abbott Diabetes Care Inc. Systems, devices, and methods for analyte monitoring
CN118613214A (zh) * 2022-01-05 2024-09-06 比奥林公司 可穿戴分析物监测设备
KR102840035B1 (ko) * 2022-01-12 2025-07-30 주식회사 아이센스 메디컬 디바이스용 어플리케이터 및 어플리케이터 조립체
TWI776779B (zh) * 2022-02-08 2022-09-01 仁寶電腦工業股份有限公司 注射式生理監測器的耗材組件以及注射式生理監測器
WO2023163957A1 (en) * 2022-02-22 2023-08-31 Metronom Health, Inc. Analyte sensor applicator
USD1023312S1 (en) * 2022-03-18 2024-04-16 Gc Corporation Hemostatic agent material
CA3245509A1 (en) * 2022-03-24 2023-09-28 F. Hoffmann-La Roche Ag INSERTION DEVICE, INSERTION SYSTEM AND METHOD FOR INSERTING A MEDICAL DEVICE
EP4248860A1 (en) * 2022-03-24 2023-09-27 Roche Diabetes Care GmbH Insertion device, insertion system and method for inserting a medical device
KR102780469B1 (ko) * 2022-04-12 2025-03-14 주식회사 아이센스 어플리케이터 및 어플리케이터 조립체
CN114831633B (zh) * 2022-04-29 2025-07-25 天津九安医疗电子股份有限公司 一种传感器植入装置
USD1057153S1 (en) 2022-04-29 2025-01-07 Biolinq Incorporated Microneedle array sensor applicator device
CN119365119A (zh) * 2022-06-17 2025-01-24 艾思蒂检测仪器有限公司 用于分析物监测装置的插入装置
JP2025527145A (ja) 2022-07-27 2025-08-20 アボット ダイアベティス ケア インコーポレイテッド 糖尿病管理のためのシステム及び方法
CN119856162A (zh) 2022-09-14 2025-04-18 雅培糖尿病护理公司 用于糖尿病管理的系统和方法
KR102877196B1 (ko) * 2022-09-14 2025-10-29 주식회사 유엑스엔 측면 걸림이 가능한 트랜스미터가 구비된 연속식 분석물 측정기
KR102877198B1 (ko) * 2022-09-15 2025-10-29 주식회사 유엑스엔 저면 걸림이 가능한 트랜스미터가 구비된 연속식 분석물 측정기
CN119894441A (zh) 2022-09-15 2025-04-25 雅培糖尿病护理公司 用于双分析物传感器的系统、装置和方法
KR102877200B1 (ko) * 2022-09-15 2025-10-29 주식회사 유엑스엔 하드 커버를 구비하는 연속식 분석물 측정기
IL319906A (en) 2022-10-21 2025-05-01 Hoffmann La Roche Insertion system and method for inserting a medical device
GB2623784A (en) * 2022-10-26 2024-05-01 Glucorx Tech Limited Analyte sensor
JP2025538349A (ja) 2022-11-17 2025-11-28 アボット ダイアベティス ケア インコーポレイテッド 薬剤投与ガイダンスに関するシステム、デバイス、及び方法
US20240240159A1 (en) 2022-11-28 2024-07-18 Abbott Diabetes Care, Inc Universal sensing system
EP4639572A1 (en) 2022-12-23 2025-10-29 Abbott Diabetes Care Inc. Systems, devices, and methods for dual analyte sensor
USD1065545S1 (en) * 2023-02-10 2025-03-04 I-Sens, Inc. Applicator for a continuous blood glucose measurement sensor
USD1065544S1 (en) * 2023-02-10 2025-03-04 I-Sens, Inc. Applicator for a continuous blood glucose measurement sensor
USD1065546S1 (en) * 2023-02-10 2025-03-04 I-Sens, Inc. Applicator for a continuous blood glucose measurement sensor
KR20260002677A (ko) 2023-04-19 2026-01-06 에프. 호프만-라 로슈 아게 삽입 장치
WO2025064603A1 (en) 2023-09-21 2025-03-27 Abbott Diabetes Care Inc. Methods, devices, and systems for adjusting laboratory hba1c values
WO2025068092A1 (en) 2023-09-26 2025-04-03 Roche Diabetes Care Gmbh Medical device for detecting an analyte in a body fluid
WO2025096917A1 (en) 2023-11-03 2025-05-08 Abbott Diabetes Care Inc. Systems, devices, and methods for sensor communications
US20250194964A1 (en) 2023-12-19 2025-06-19 Abbott Diabetes Care, Inc. Glucose oxidase sensors with improved stability
WO2025165721A1 (en) 2024-01-30 2025-08-07 Abbott Diabetes Care Inc. Systems and methods for diabetes management
WO2025186150A1 (en) 2024-03-05 2025-09-12 Roche Diabetes Care Gmbh Inserter attachment device
WO2025190934A1 (en) 2024-03-14 2025-09-18 Roche Diabetes Care Gmbh Insertion device
WO2025208053A2 (en) 2024-03-28 2025-10-02 Abbott Diabetes Care Inc. Systems and methods for medication dosing and titration
WO2026025065A2 (en) 2024-07-26 2026-01-29 Abbott Diabetes Care Inc. Systems and methods for titrating a basal insulin dose and for detecting non-compliance with dose recommendations
WO2026027588A1 (en) 2024-08-01 2026-02-05 Roche Diabetes Care Gmbh Insertion device and method for inserting a medical device

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060020189A1 (en) * 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
US20080114280A1 (en) * 2006-10-23 2008-05-15 Gary Ashley Stafford Variable speed sensor insertion devices and methods of use
US20080167578A1 (en) * 2005-11-30 2008-07-10 Abbott Diabetes Care, Inc. Integrated Meter for Analyzing Biological Samples
US20090054866A1 (en) * 2005-01-24 2009-02-26 Novo Nordisk A/S Transcutaneous Device Assembly
US20090198215A1 (en) * 2007-04-30 2009-08-06 Medtronic Minimed, Inc. Adhesive patch systems and methods

Family Cites Families (1977)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3123790A (en) 1964-03-03 tyler
CA200201A (en) * 1920-05-18 The Connecticut Electric Manufacturing Company Mechanical movement
US2008A (en) 1841-03-18 Gas-lamp eok conducting gas pkom ah elevated buhner to one below it
US2402306A (en) 1943-10-07 1946-06-18 Turkel Henry Retaining guard guide for needles
DE902776C (de) 1949-08-17 1954-01-28 August Rooseboom Selbsttaetiger Injektionsapparat mit Ampulle
US3132123A (en) 1960-11-25 1964-05-05 Du Pont Polymers of perfluoroalkoxy perfluorovinyl ethers
US3211001A (en) 1961-08-01 1965-10-12 Barber Colman Co Temperature sensing device
NL286398A (enExample) 1961-12-08 1900-01-01
US3260656A (en) 1962-09-27 1966-07-12 Corning Glass Works Method and apparatus for electrolytically determining a species in a fluid
US3517670A (en) 1967-11-09 1970-06-30 Propper Mfg Co Inc Blood-letting lancet
GB1191363A (en) 1968-02-19 1970-05-13 Pavelle Ltd Improvements in or relating to Electronic Thermostats.
US3522807A (en) 1968-10-02 1970-08-04 Bluma Millenbach Fecal receptacle
US3653841A (en) 1969-12-19 1972-04-04 Hoffmann La Roche Methods and compositions for determining glucose in blood
US3670727A (en) 1970-04-16 1972-06-20 American Hospital Supply Corp Medical infusion set
US3776832A (en) 1970-11-10 1973-12-04 Energetics Science Electrochemical detection cell
US3719564A (en) 1971-05-10 1973-03-06 Philip Morris Inc Method of determining a reducible gas concentration and sensor therefor
US3837339A (en) 1972-02-03 1974-09-24 Whittaker Corp Blood glucose level monitoring-alarm system and method therefor
US3949388A (en) 1972-11-13 1976-04-06 Monitron Industries, Inc. Physiological sensor and transmitter
US3908657A (en) 1973-01-15 1975-09-30 Univ Johns Hopkins System for continuous withdrawal of blood
GB1394171A (en) 1973-05-16 1975-05-14 Whittaker Corp Blood glucose level monitoring-alarm system and method therefor
US4100048A (en) 1973-09-20 1978-07-11 U.S. Philips Corporation Polarographic cell
US3926760A (en) 1973-09-28 1975-12-16 Du Pont Process for electrophoretic deposition of polymer
US3972320A (en) 1974-08-12 1976-08-03 Gabor Ujhelyi Kalman Patient monitoring system
JPS5512406Y2 (enExample) 1974-12-20 1980-03-18
US4245634A (en) 1975-01-22 1981-01-20 Hospital For Sick Children Artificial beta cell
JPS5441191Y2 (enExample) 1975-02-21 1979-12-03
US4036749A (en) 1975-04-30 1977-07-19 Anderson Donald R Purification of saline water
JPS5510583Y2 (enExample) 1975-07-07 1980-03-07
JPS5510584Y2 (enExample) 1975-08-19 1980-03-07
US3960497A (en) 1975-08-19 1976-06-01 Beckman Instruments, Inc. Chemical analyzer with automatic calibration
JPS5510581Y2 (enExample) 1975-09-06 1980-03-07
US4033330A (en) 1975-09-08 1977-07-05 Hewlett-Packard Company Transcutaneous pH measuring instrument
US3979274A (en) 1975-09-24 1976-09-07 The Yellow Springs Instrument Company, Inc. Membrane for enzyme electrodes
DE2645048A1 (de) 1975-10-08 1977-04-21 Gen Electric Einpflanzbarer elektrochemischer sensor
US4016866A (en) 1975-12-18 1977-04-12 General Electric Company Implantable electrochemical sensor
US4055175A (en) 1976-05-07 1977-10-25 Miles Laboratories, Inc. Blood glucose control apparatus
DE2625834B2 (de) 1976-06-09 1978-10-12 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Bestimmung von Substraten oder Enzymaktivitäten
US4059406A (en) 1976-07-12 1977-11-22 E D T Supplies Limited Electrochemical detector system
DE2642896C3 (de) 1976-09-24 1980-08-21 7800 Freiburg Präzisionsschnepper zum Setzen von Normstichwunden in die Haut für Diagnosezwecke
US4076596A (en) 1976-10-07 1978-02-28 Leeds & Northrup Company Apparatus for electrolytically determining a species in a fluid and method of use
US4129128A (en) 1977-02-23 1978-12-12 Mcfarlane Richard H Securing device for catheter placement assembly
FR2387659A1 (fr) 1977-04-21 1978-11-17 Armines Dispositif de controle et regulation de la glycemie
US4098574A (en) 1977-08-01 1978-07-04 Eastman Kodak Company Glucose detection system free from fluoride-ion interference
JPS5441191A (en) 1977-09-08 1979-04-02 Omron Tateisi Electronics Co Glucose-oxygen sensitive electrode
US4178916A (en) 1977-09-26 1979-12-18 Mcnamara Elger W Diabetic insulin alarm system
JPS5912135B2 (ja) 1977-09-28 1984-03-21 松下電器産業株式会社 酵素電極
US4151845A (en) 1977-11-25 1979-05-01 Miles Laboratories, Inc. Blood glucose control apparatus
JPS5921500B2 (ja) 1978-01-28 1984-05-21 東洋紡績株式会社 酸素電極用酵素膜
DK151000C (da) 1978-02-17 1988-06-13 Radiometer As Fremgangsmaade og apparat til bestemmelse af en patients in vivo plasma-ph-vaerdi
FR2420331A1 (fr) 1978-03-23 1979-10-19 Claude Bernard Tete de mesure combinee, destinee a etre mise en place sur ou dans des parties corporelles, permettant l'obtention simultanee de signaux de mesure relatifs a une activite electrique d'une part et a une activite ionique d'autre part
US4172770A (en) 1978-03-27 1979-10-30 Technicon Instruments Corporation Flow-through electrochemical system analytical method
DE2817363C2 (de) 1978-04-20 1984-01-26 Siemens AG, 1000 Berlin und 8000 München Verfahren zur Konzentrationsbestimmung von Zucker und dafür geeigneter elektrokatalytischer Zuckersensor
JPS567234Y2 (enExample) 1978-06-30 1981-02-17
JPS5816697B2 (ja) 1978-07-10 1983-04-01 松下電器産業株式会社 酵素電極およびその製造法
JPS5816698B2 (ja) 1978-07-10 1983-04-01 松下電器産業株式会社 酵素電極およびその製造法
JPS5816696B2 (ja) 1978-07-10 1983-04-01 松下電器産業株式会社 酵素電極
JPS5512406A (en) 1978-07-12 1980-01-29 Nippon Seiko Kk Method of compensating error in measuring circle or arc and meter with compensator
US4344438A (en) 1978-08-02 1982-08-17 The United States Of America As Represented By The Department Of Health, Education And Welfare Optical sensor of plasma constituents
HU177369B (en) 1978-09-08 1981-09-28 Radelkis Electrokemiai Industrial molecule-selective sensing device and method for producing same
US4240438A (en) 1978-10-02 1980-12-23 Wisconsin Alumni Research Foundation Method for monitoring blood glucose levels and elements
DE2965939D1 (en) 1978-10-02 1983-08-25 Xerox Corp Electrostatographic processing system
AU530979B2 (en) 1978-12-07 1983-08-04 Aus. Training Aids Pty. Ltd., Detecting position of bullet fired at target
US4247297A (en) 1979-02-23 1981-01-27 Miles Laboratories, Inc. Test means and method for interference resistant determination of oxidizing substances
US4373527B1 (en) 1979-04-27 1995-06-27 Univ Johns Hopkins Implantable programmable medication infusion system
US4573994A (en) 1979-04-27 1986-03-04 The Johns Hopkins University Refillable medication infusion apparatus
US4305401A (en) 1979-05-16 1981-12-15 Hughes Aircraft Company Digital watch/infrared plethysmograph having a quick release remote pulse sensor having a finger cuff
US4365637A (en) 1979-07-05 1982-12-28 Dia-Med, Inc. Perspiration indicating alarm for diabetics
CS210174B1 (en) 1979-07-12 1982-01-29 Ivan Emmer Method of making the electric hygrometric sensor
US4401122A (en) 1979-08-02 1983-08-30 Children's Hospital Medical Center Cutaneous methods of measuring body substances
US4458686A (en) 1979-08-02 1984-07-10 Children's Hospital Medical Center Cutaneous methods of measuring body substances
US4293396A (en) 1979-09-27 1981-10-06 Prototech Company Thin carbon-cloth-based electrocatalytic gas diffusion electrodes, and electrochemical cells comprising the same
GB2067764B (en) 1980-01-09 1984-01-25 Nat Res Dev Transcutaneous gas sensor
DE3114441A1 (de) 1980-04-11 1982-03-04 Radiometer A/S, 2400 Koebenhavn Elektrochemische messelektrodeneinrichtung
US4450842A (en) 1980-04-25 1984-05-29 Cordis Corporation Solid state reference electrode
JPS56163447U (enExample) 1980-05-07 1981-12-04
JPS56163447A (en) 1980-05-22 1981-12-16 Matsushita Electric Ind Co Ltd Enzyme electrode
US4340458A (en) 1980-06-02 1982-07-20 Joslin Diabetes Center, Inc. Glucose sensor
US4404066A (en) 1980-08-25 1983-09-13 The Yellow Springs Instrument Company Method for quantitatively determining a particular substrate catalyzed by a multisubstrate enzyme
US4356074A (en) 1980-08-25 1982-10-26 The Yellow Springs Instrument Company, Inc. Substrate specific galactose oxidase enzyme electrodes
US4352960A (en) 1980-09-30 1982-10-05 Baptist Medical Center Of Oklahoma, Inc. Magnetic transcutaneous mount for external device of an associated implant
USRE32947E (en) 1980-09-30 1989-06-13 Baptist Medical Center Of Oklahoma, Inc. Magnetic transcutaneous mount for external device of an associated implant
JPS5770448U (enExample) 1980-10-14 1982-04-28
JPS5770448A (en) 1980-10-20 1982-04-30 Matsushita Electric Ind Co Ltd Enzyme electrode
US4425920A (en) 1980-10-24 1984-01-17 Purdue Research Foundation Apparatus and method for measurement and control of blood pressure
US4327725A (en) 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
US4390621A (en) 1980-12-15 1983-06-28 Miles Laboratories, Inc. Method and device for detecting glucose concentration
US4353888A (en) 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
US4436094A (en) 1981-03-09 1984-03-13 Evreka, Inc. Monitor for continuous in vivo measurement of glucose concentration
US4427004A (en) 1981-03-16 1984-01-24 Viridan Inc. Annular flow entrainment nebulizer
US4553541A (en) 1981-03-23 1985-11-19 Becton, Dickinson And Co. Automatic retractable lancet assembly
JPS57160784A (en) 1981-03-31 1982-10-04 Yamaha Motor Co Ltd Rear fender for autobicycle
AT369254B (de) 1981-05-07 1982-12-27 Otto Dipl Ing Dr Tech Prohaska Medizinische sonde
FR2508305B1 (fr) 1981-06-25 1986-04-11 Slama Gerard Dispositif pour provoquer une petite piqure en vue de recueillir une goutte de sang
US4622966A (en) 1981-06-30 1986-11-18 Abbott Laboratories Surgical cutting device
US4392849A (en) 1981-07-27 1983-07-12 The Cleveland Clinic Foundation Infusion pump controller
US4440175A (en) 1981-08-10 1984-04-03 University Patents, Inc. Membrane electrode for non-ionic species
DE3138194A1 (de) 1981-09-25 1983-04-14 Basf Ag, 6700 Ludwigshafen Wasserunloesliches poroeses proteinmaterial, dessen herstellung und verwendung
DE3278334D1 (en) 1981-10-23 1988-05-19 Genetics Int Inc Sensor for components of a liquid mixture
US4431004A (en) 1981-10-27 1984-02-14 Bessman Samuel P Implantable glucose sensor
US4418148A (en) 1981-11-05 1983-11-29 Miles Laboratories, Inc. Multilayer enzyme electrode membrane
JPS5886083A (ja) 1981-11-12 1983-05-23 Wako Pure Chem Ind Ltd グリセロ−ル−３−リン酸オキシダ−ゼの安定化剤
US4494950A (en) 1982-01-19 1985-01-22 The Johns Hopkins University Plural module medication delivery system
JPS58153154A (ja) 1982-03-09 1983-09-12 Ajinomoto Co Inc 修飾電極
US4581336A (en) 1982-04-26 1986-04-08 Uop Inc. Surface-modified electrodes
FI831399L (fi) 1982-04-29 1983-10-30 Agripat Sa Kontaktlins av haerdad polyvinylalkohol
DE3221339A1 (de) 1982-06-05 1983-12-08 Basf Ag, 6700 Ludwigshafen Verfahren zur elektrochemischen hydrierung von nicotinamidadenin-dinucleotid
US4427770A (en) 1982-06-14 1984-01-24 Miles Laboratories, Inc. High glucose-determining analytical element
EP0098592A3 (en) 1982-07-06 1985-08-21 Fujisawa Pharmaceutical Co., Ltd. Portable artificial pancreas
US4509531A (en) 1982-07-28 1985-04-09 Teledyne Industries, Inc. Personal physiological monitor
US4534356A (en) 1982-07-30 1985-08-13 Diamond Shamrock Chemicals Company Solid state transcutaneous blood gas sensors
DE3228551A1 (de) 1982-07-30 1984-02-02 Siemens AG, 1000 Berlin und 8000 München Verfahren zur bestimmung der zuckerkonzentration
US4571292A (en) 1982-08-12 1986-02-18 Case Western Reserve University Apparatus for electrochemical measurements
US4464170A (en) 1982-09-29 1984-08-07 Miles Laboratories, Inc. Blood glucose control apparatus and method
GB2128453A (en) 1982-10-08 1984-04-26 Philips Electronic Associated System identification in communications systems
US4552840A (en) 1982-12-02 1985-11-12 California And Hawaiian Sugar Company Enzyme electrode and method for dextran analysis
US4527240A (en) 1982-12-29 1985-07-02 Kvitash Vadim I Balascopy method for detecting and rapidly evaluating multiple imbalances within multi-parametric systems
JPS59138086A (ja) 1983-01-25 1984-08-08 シャープ株式会社 基板接続方法
US4461691A (en) 1983-02-10 1984-07-24 The United States Of America As Represented By The United States Department Of Energy Organic conductive films for semiconductor electrodes
US4679562A (en) 1983-02-16 1987-07-14 Cardiac Pacemakers, Inc. Glucose sensor
EP0136362B1 (en) 1983-03-11 1990-12-19 Matsushita Electric Industrial Co., Ltd. Biosensor
IT1170375B (it) 1983-04-19 1987-06-03 Giuseppe Bombardieri Apparecchio che infonde insulina o glucosio nel soggetto diabetico sulla base di determinazioni di concentrazioni di glucosio ottenute senza bisogno di prelievi del sangue del paziente
CA1219040A (en) 1983-05-05 1987-03-10 Elliot V. Plotkin Measurement of enzyme-catalysed reactions
CA1226036A (en) 1983-05-05 1987-08-25 Irving J. Higgins Analytical equipment and sensor electrodes therefor
GB2154003B (en) 1983-12-16 1988-02-17 Genetics Int Inc Diagnostic aid
US5682884A (en) 1983-05-05 1997-11-04 Medisense, Inc. Strip electrode with screen printing
US5509410A (en) 1983-06-06 1996-04-23 Medisense, Inc. Strip electrode including screen printing of a single layer
CA1218704A (en) 1983-05-05 1987-03-03 Graham Davis Assay systems using more than one enzyme
CA1220818A (en) 1983-05-05 1987-04-21 Hugh A.O. Hill Assay techniques utilising specific binding agents
US4650547A (en) 1983-05-19 1987-03-17 The Regents Of The University Of California Method and membrane applicable to implantable sensor
US4484987A (en) 1983-05-19 1984-11-27 The Regents Of The University Of California Method and membrane applicable to implantable sensor
US4675346A (en) 1983-06-20 1987-06-23 Loctite Corporation UV curable silicone rubber compositions
WO1985000463A1 (en) 1983-07-05 1985-01-31 Matsushita Electric Industrial Co., Ltd. Aluminum electrolytic capacitor and method of manufacture thereof
US4524114A (en) 1983-07-05 1985-06-18 Allied Corporation Bifunctional air electrode
US4538616A (en) 1983-07-25 1985-09-03 Robert Rogoff Blood sugar level sensing and monitoring transducer
US4655880A (en) 1983-08-01 1987-04-07 Case Western Reserve University Apparatus and method for sensing species, substances and substrates using oxidase
US4543955A (en) 1983-08-01 1985-10-01 Cordis Corporation System for controlling body implantable action device
USRE33191E (en) * 1983-08-23 1990-04-03 Blister pack panel for face powder compact display
US5190546A (en) 1983-10-14 1993-03-02 Raychem Corporation Medical devices incorporating SIM alloy elements
US4665906A (en) 1983-10-14 1987-05-19 Raychem Corporation Medical devices incorporating sim alloy elements
US5067957A (en) 1983-10-14 1991-11-26 Raychem Corporation Method of inserting medical devices incorporating SIM alloy elements
SE8305704D0 (sv) 1983-10-18 1983-10-18 Leo Ab Cuvette
US4560534A (en) 1983-11-02 1985-12-24 Miles Laboratories, Inc. Polymer catalyst transducers
US4522690A (en) 1983-12-01 1985-06-11 Honeywell Inc. Electrochemical sensing of carbon monoxide
US6017335A (en) 1983-12-12 2000-01-25 Burnham; Warren R. Method for making a tubular product, especially a catheter, and article made thereby
DE3479522D1 (en) 1983-12-16 1989-09-28 Medisense Inc Assay for nucleic acids
JPH0640086B2 (ja) 1984-02-20 1994-05-25 松下電器産業株式会社 バイオセンサ
JPS60173458A (ja) 1984-02-20 1985-09-06 Matsushita Electric Ind Co Ltd バイオセンサ
JPS60173457A (ja) 1984-02-20 1985-09-06 Matsushita Electric Ind Co Ltd バイオセンサ
US4592745A (en) 1984-02-29 1986-06-03 Novo Industri A/S Dispenser
SU1281988A1 (ru) 1984-03-15 1987-01-07 Институт биохимии АН ЛитССР Электрохимический датчик дл измерени концентрации глюкозы
JPS60173457U (ja) 1984-04-27 1985-11-16 三菱自動車工業株式会社 車両用ウオツシヤ装置
JPS60173459U (ja) 1984-04-27 1985-11-16 トヨタ自動車株式会社 パ−キングブレ−キのブレ−キケ−ブル
EP0179823B1 (fr) 1984-04-30 1989-07-12 Stiftung, R. E. Procede de sensibilisation d'un photo-catalyseur d'oxydo-reduction et photo-catalyseur ainsi obtenu
JPS60261186A (ja) 1984-06-08 1985-12-24 Nippon Telegr & Teleph Corp <Ntt> 光モジユ−ル製造法
US5141868A (en) 1984-06-13 1992-08-25 Internationale Octrooi Maatschappij "Octropa" Bv Device for use in chemical test procedures
WO1986000141A1 (en) 1984-06-13 1986-01-03 Unilever Plc Devices for use in chemical test procedures
DK8601218A (enExample) 1984-07-18 1986-03-17
DE3429596A1 (de) 1984-08-10 1986-02-20 Siemens AG, 1000 Berlin und 8000 München Vorrichtung zur physiologischen frequenzsteuerung eines mit einer reizelektrode versehenen herzschrittmachers
US4820399A (en) 1984-08-31 1989-04-11 Shimadzu Corporation Enzyme electrodes
CA1254091A (en) 1984-09-28 1989-05-16 Vladimir Feingold Implantable medication infusion system
JPS61111428A (ja) 1984-11-06 1986-05-29 Terumo Corp 電子体温計
GB2168815A (en) 1984-11-13 1986-06-25 Genetics Int Inc Bioelectrochemical assay electrode
US4627842A (en) 1984-11-19 1986-12-09 William Katz Intravenous needle assembly
US4690675A (en) 1984-11-19 1987-09-01 William Katz Intravenous needle assembly
US4717673A (en) 1984-11-23 1988-01-05 Massachusetts Institute Of Technology Microelectrochemical devices
US4721601A (en) 1984-11-23 1988-01-26 Massachusetts Institute Of Technology Molecule-based microelectronic devices
JPH0617889B2 (ja) 1984-11-27 1994-03-09 株式会社日立製作所 生物化学センサ
DE3585915T2 (de) 1984-12-28 1993-04-15 Terumo Corp Ionensensor.
GB8500729D0 (en) 1985-01-11 1985-02-13 Hill H A O Surface-modified electrode
US4847785A (en) 1985-01-22 1989-07-11 International Business Machines Corp. Interactive display for trend or bar graph
DE3502913C1 (de) 1985-01-29 1986-07-03 Günter Prof. Dr.rer.nat. 5100 Aachen Rau Messaufnehmer zur nichtinvasiven Erfassung elektrophysiologischer Groessen
AU5481786A (en) 1985-03-20 1986-09-25 Hochmair, E.S. Transcutaneous power and signal transmission system
JPH0772585B2 (ja) 1985-03-29 1995-08-02 バンドー化学株式会社 エンジン用補機のベルト伝動装置
US5279294A (en) 1985-04-08 1994-01-18 Cascade Medical, Inc. Medical diagnostic system
US4627445A (en) 1985-04-08 1986-12-09 Garid, Inc. Glucose medical monitoring system
US4781798A (en) 1985-04-19 1988-11-01 The Regents Of The University Of California Transparent multi-oxygen sensor array and method of using same
JPH0320752Y2 (enExample) 1985-06-13 1991-05-07
US4671288A (en) 1985-06-13 1987-06-09 The Regents Of The University Of California Electrochemical cell sensor for continuous short-term use in tissues and blood
EP0230472B2 (en) 1985-06-21 2000-12-13 Matsushita Electric Industrial Co., Ltd. Biosensor and method of manufacturing same
US4938860A (en) 1985-06-28 1990-07-03 Miles Inc. Electrode for electrochemical sensors
US4796634A (en) 1985-08-09 1989-01-10 Lawrence Medical Systems, Inc. Methods and apparatus for monitoring cardiac output
JPS6260428A (ja) 1985-09-06 1987-03-17 株式会社明電舎 環線系統保護装置
US4805624A (en) 1985-09-09 1989-02-21 The Montefiore Hospital Association Of Western Pa Low-potential electrochemical redox sensors
US5245314A (en) 1985-09-18 1993-09-14 Kah Jr Carl L C Location monitoring system
US4680268A (en) 1985-09-18 1987-07-14 Children's Hospital Medical Center Implantable gas-containing biosensor and method for measuring an analyte such as glucose
US4890620A (en) 1985-09-20 1990-01-02 The Regents Of The University Of California Two-dimensional diffusion glucose substrate sensing electrode
JPS6285855A (ja) 1985-10-11 1987-04-20 Nok Corp 微小金電極の形成方法
US4627908A (en) 1985-10-24 1986-12-09 Chevron Research Company Process for stabilizing lube base stocks derived from bright stock
US4684245A (en) 1985-10-28 1987-08-04 Oximetrix, Inc. Electro-optical coupler for catheter oximeter
CA1254616A (en) 1985-11-11 1989-05-23 Calum J. Mcneil Electrochemical enzymic assay procedures
JPS62114747A (ja) 1985-11-15 1987-05-26 O C C:Kk 結晶が鋳造方向に長く伸びた一方向凝固組織を有する金属条の連続鋳造法
JPS6285855U (enExample) 1985-11-16 1987-06-01
GB8529300D0 (en) 1985-11-28 1986-01-02 Ici Plc Membrane
JPS62114747U (enExample) 1986-01-10 1987-07-21
US4755173A (en) 1986-02-25 1988-07-05 Pacesetter Infusion, Ltd. Soft cannula subcutaneous injection set
US4776944A (en) 1986-03-20 1988-10-11 Jiri Janata Chemical selective sensors utilizing admittance modulated membranes
US4685463A (en) 1986-04-03 1987-08-11 Williams R Bruce Device for continuous in vivo measurement of blood glucose concentrations
GB8608700D0 (en) 1986-04-10 1986-05-14 Genetics Int Inc Measurement of electroactive species in solution
US4726378A (en) 1986-04-11 1988-02-23 Minnesota Mining And Manufacturing Company Adjustable magnetic supercutaneous device and transcutaneous coupling apparatus
US4757022A (en) 1986-04-15 1988-07-12 Markwell Medical Institute, Inc. Biological fluid measuring device
US4994167A (en) 1986-04-15 1991-02-19 Markwell Medical Institute, Inc. Biological fluid measuring device
US4711247A (en) 1986-04-18 1987-12-08 Henry Fishman Allergy testing method and apparatus
US4909908A (en) 1986-04-24 1990-03-20 Pepi Ross Electrochemical cncentration detector method
DE3614821A1 (de) 1986-05-02 1987-11-05 Siemens Ag Implantierbare, eichbare messvorrichtung fuer eine koerpersubstanz sowie eichverfahren
US4703756A (en) 1986-05-06 1987-11-03 The Regents Of The University Of California Complete glucose monitoring system with an implantable, telemetered sensor module
US4731726A (en) 1986-05-19 1988-03-15 Healthware Corporation Patient-operated glucose monitor and diabetes management system
DE3617161A1 (de) 1986-05-22 1987-11-26 Boehringer Mannheim Gmbh System zur bestimmung der konzentration von bestandteilen von koerperfluessigkeiten
GB8612861D0 (en) 1986-05-27 1986-07-02 Cambridge Life Sciences Immobilised enzyme biosensors
US4698057A (en) 1986-06-09 1987-10-06 Joishy Suresh K Built in assembly for stabilizing and securing intravascular needle or catheter like device
US4969468A (en) 1986-06-17 1990-11-13 Alfred E. Mann Foundation For Scientific Research Electrode array for use in connection with a living body and method of manufacture
AU598820B2 (en) 1986-06-20 1990-07-05 Molecular Devices Corporation Zero volume electrochemical cell
US5001054A (en) 1986-06-26 1991-03-19 Becton, Dickinson And Company Method for monitoring glucose
JPS636451A (ja) 1986-06-27 1988-01-12 Terumo Corp 酵素センサ
US4764416A (en) 1986-07-01 1988-08-16 Mitsubishi Denki Kabushiki Kaisha Electric element circuit using oxidation-reduction substances
US4917800A (en) 1986-07-07 1990-04-17 Bend Research, Inc. Functional, photochemically active, and chemically asymmetric membranes by interfacial polymerization of derivatized multifunctional prepolymers
US4784736A (en) 1986-07-07 1988-11-15 Bend Research, Inc. Functional, photochemically active, and chemically asymmetric membranes by interfacial polymerization of derivatized multifunctional prepolymers
JPH0326956Y2 (enExample) 1986-07-14 1991-06-11
US4726716A (en) 1986-07-21 1988-02-23 Mcguire Thomas V Fastener for catheter
GB8618022D0 (en) 1986-07-23 1986-08-28 Unilever Plc Electrochemical measurements
GB8618578D0 (en) 1986-07-30 1986-09-10 Turner R C Lancet device
JPH0654304B2 (ja) 1986-08-28 1994-07-20 松下電器産業株式会社 バイオセンサ
US4894137A (en) 1986-09-12 1990-01-16 Omron Tateisi Electronics Co. Enzyme electrode
US5055171A (en) 1986-10-06 1991-10-08 T And G Corporation Ionic semiconductor materials and applications thereof
US4865038A (en) 1986-10-09 1989-09-12 Novametrix Medical Systems, Inc. Sensor appliance for non-invasive monitoring
US4897162A (en) 1986-11-14 1990-01-30 The Cleveland Clinic Foundation Pulse voltammetry
JPS63128252A (ja) 1986-11-18 1988-05-31 Matsushita Electric Ind Co Ltd バイオセンサ
JPS63139246A (ja) 1986-12-01 1988-06-11 Matsushita Electric Ind Co Ltd バイオセンサ
DE3700119A1 (de) 1987-01-03 1988-07-14 Inst Diabetestechnologie Gemei Implantierbarer elektrochemischer sensor
US4934369A (en) 1987-01-30 1990-06-19 Minnesota Mining And Manufacturing Company Intravascular blood parameter measurement system
EP0278647A3 (en) 1987-02-09 1989-09-20 AT&T Corp. Electronchemical processes involving enzymes
JPS63128252U (enExample) 1987-02-17 1988-08-22
GB2201248B (en) 1987-02-24 1991-04-17 Ici Plc Enzyme electrode sensors
US4777953A (en) 1987-02-25 1988-10-18 Ash Medical Systems, Inc. Capillary filtration and collection method for long-term monitoring of blood constituents
US5002054A (en) 1987-02-25 1991-03-26 Ash Medical Systems, Inc. Interstitial filtration and collection device and method for long-term monitoring of physiological constituents of the body
US4854322A (en) 1987-02-25 1989-08-08 Ash Medical Systems, Inc. Capillary filtration and collection device for long-term monitoring of blood constituents
JPS63139246U (enExample) 1987-03-03 1988-09-13
GB2204408A (en) 1987-03-04 1988-11-09 Plessey Co Plc Biosensor device
US4848351A (en) 1987-03-04 1989-07-18 Sentry Medical Products, Inc. Medical electrode assembly
US4923586A (en) 1987-03-31 1990-05-08 Daikin Industries, Ltd. Enzyme electrode unit
US4935345A (en) 1987-04-07 1990-06-19 Arizona Board Of Regents Implantable microelectronic biochemical sensor incorporating thin film thermopile
US5352348A (en) 1987-04-09 1994-10-04 Nova Biomedical Corporation Method of using enzyme electrode
US4759828A (en) 1987-04-09 1988-07-26 Nova Biomedical Corporation Glucose electrode and method of determining glucose
US4749985A (en) 1987-04-13 1988-06-07 United States Of America As Represented By The United States Department Of Energy Functional relationship-based alarm processing
US4781683A (en) 1987-04-22 1988-11-01 The Johns Hopkins University Single-use, self-annulling injection syringe
EP0290683A3 (en) 1987-05-01 1988-12-14 Diva Medical Systems B.V. Diabetes management system and apparatus
JPH0328752Y2 (enExample) 1987-05-18 1991-06-20
JPH0761280B2 (ja) 1987-05-27 1995-07-05 日本化薬株式会社 グルコ−ス及び１，５−アンヒドログルシト−ルの同時測定法
US4785868A (en) 1987-06-04 1988-11-22 Titan Medical, Inc. Medical needle and method for making
US5286364A (en) 1987-06-08 1994-02-15 Rutgers University Surface-modified electochemical biosensor
JPS63317757A (ja) 1987-06-19 1988-12-26 Matsushita Electric Ind Co Ltd グルコ−スセンサ
JPS63317758A (ja) 1987-06-19 1988-12-26 Matsushita Electric Ind Co Ltd バイオセンサの製造法
US4822337A (en) 1987-06-22 1989-04-18 Stanley Newhouse Insulin delivery method and apparatus
JPH07122624B2 (ja) 1987-07-06 1995-12-25 ダイキン工業株式会社 バイオセンサ
GB8718430D0 (en) 1987-08-04 1987-09-09 Ici Plc Sensor
US4874500A (en) 1987-07-15 1989-10-17 Sri International Microelectrochemical sensor and sensor array
JPS6423155A (en) 1987-07-17 1989-01-25 Daikin Ind Ltd Electrode refreshing device for biosensor
EP0378683B1 (en) 1987-08-11 1995-11-02 Terumo Kabushiki Kaisha Automatic sphygmomanometer
US4974929A (en) 1987-09-22 1990-12-04 Baxter International, Inc. Fiber optical probe connector for physiologic measurement devices
NL8702370A (nl) 1987-10-05 1989-05-01 Groningen Science Park Werkwijze en stelsel voor glucosebepaling en daarvoor bruikbaar meetcelsamenstel.
US4815469A (en) 1987-10-08 1989-03-28 Siemens-Pacesetter, Inc. Implantable blood oxygen sensor and method of use
US4818994A (en) 1987-10-22 1989-04-04 Rosemount Inc. Transmitter with internal serial bus
JPH0755757Y2 (ja) 1987-10-27 1995-12-20 ティアツク株式会社 記録再生装置の交換アダプタ
JPH01114746A (ja) 1987-10-29 1989-05-08 Matsushita Electric Ind Co Ltd バイオセンサ
JPH0795056B2 (ja) 1987-10-29 1995-10-11 松下電器産業株式会社 バイオセンサ
GB8725936D0 (en) 1987-11-05 1987-12-09 Genetics Int Inc Sensing system
JP2627512B2 (ja) 1987-11-09 1997-07-09 株式会社日立製作所 ネツトワーク図作成装置
JP2502635B2 (ja) 1987-11-19 1996-05-29 松下電器産業株式会社 バイオセンサ
JPH01140054A (ja) 1987-11-26 1989-06-01 Nec Corp グルコースセンサ
DK158130C (da) 1987-11-30 1990-09-03 Uno Plast As Apparat til opsamling og maaling af legemsvaeske
US5006110A (en) 1987-12-01 1991-04-09 Pacesetter Infusion, Ltd. Air-in-line detector infusion system
JP2574347B2 (ja) 1987-12-15 1997-01-22 松下電器産業株式会社 バイオセンサ
US4813424A (en) 1987-12-23 1989-03-21 University Of New Mexico Long-life membrane electrode for non-ionic species
US4856648A (en) * 1987-12-31 1989-08-15 Steri-Oss, Inc. Packaging & installing implants
JPH01114747U (enExample) 1988-01-27 1989-08-02
JPH0613478Y2 (ja) 1988-03-09 1994-04-06 財団法人鉄道総合技術研究所 透水性測定器
US5128015A (en) 1988-03-15 1992-07-07 Tall Oak Ventures Method and apparatus for amperometric diagnostic analysis
US5108564A (en) 1988-03-15 1992-04-28 Tall Oak Ventures Method and apparatus for amperometric diagnostic analysis
US5205297A (en) 1988-03-25 1993-04-27 Lectec Corporation Multipurpose medical stimulation electrode
DE68924026T3 (de) 1988-03-31 2008-01-10 Matsushita Electric Industrial Co., Ltd., Kadoma Biosensor und dessen herstellung.
US4921199A (en) 1988-04-25 1990-05-01 Villaveces James W Device for aiding in preparation of intravenous therapy
GB8817421D0 (en) 1988-07-21 1988-08-24 Medisense Inc Bioelectrochemical electrodes
US4925268A (en) 1988-07-25 1990-05-15 Abbott Laboratories Fiber-optic physiological probes
US4954129A (en) 1988-07-25 1990-09-04 Abbott Laboratories Hydrodynamic clot flushing
EP0353328A1 (en) 1988-08-03 1990-02-07 Dräger Nederland B.V. A polarographic-amperometric three-electrode sensor
US5340722A (en) 1988-08-24 1994-08-23 Avl Medical Instruments Ag Method for the determination of the concentration of an enzyme substrate and a sensor for carrying out the method
JPH0262958A (ja) 1988-08-30 1990-03-02 Kanzaki Paper Mfg Co Ltd リン酸濃度測定方法
US5899856A (en) 1988-09-08 1999-05-04 Sudormed, Inc. Dermal patch detecting long-term alcohol consumption and method of use
US5264106A (en) 1988-10-07 1993-11-23 Medisense, Inc. Enhanced amperometric sensor
US4924879A (en) 1988-10-07 1990-05-15 Brien Walter J O Blood lancet device
US5108889A (en) 1988-10-12 1992-04-28 Thorne, Smith, Astill Technologies, Inc. Assay for determining analyte using mercury release followed by detection via interaction with aluminum
JPH0320752A (ja) 1989-06-16 1991-01-29 Daikin Ind Ltd 静電荷現像用キャリアー
US4895147A (en) 1988-10-28 1990-01-23 Sherwood Medical Company Lancet injector
JP2689531B2 (ja) 1988-10-31 1997-12-10 エヌオーケー株式会社 グルコースセンサ
JPH02128152A (ja) 1988-11-08 1990-05-16 Nec Corp 酵素固定化方法及びバイオセンサ
WO1990005300A1 (en) 1988-11-10 1990-05-17 Midwest Research Technologies, Inc. Method for electrical detection of a binding reaction
US5200051A (en) 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
US5360404A (en) 1988-12-14 1994-11-01 Inviro Medical Devices Ltd. Needle guard and needle assembly for syringe
US5068536A (en) 1989-01-19 1991-11-26 Futrex, Inc. Method for providing custom calibration for near infrared instruments for measurement of blood glucose
AT393213B (de) 1989-02-08 1991-09-10 Avl Verbrennungskraft Messtech Vorrichtung zur bestimmung zumindest einer medizinischen messgroesse
US5305008A (en) 1991-08-12 1994-04-19 Integrated Silicon Design Pty. Ltd. Transponder system
EP0384504A1 (en) 1989-02-24 1990-08-29 Duphar International Research B.V Detection strip for detecting and identifying chemical air contaminants, and portable detection kit comprising said strips
DK0385805T3 (da) 1989-03-03 1996-09-23 Edward W Stark Fremgangsmåde og apparat til signalbehandling
US5205920A (en) 1989-03-03 1993-04-27 Noboru Oyama Enzyme sensor and method of manufacturing the same
JPH02120655U (enExample) 1989-03-14 1990-09-28
JPH02298855A (ja) 1989-03-20 1990-12-11 Assoc Univ Inc 固定化酵素とレドックス重合体を用いた電気化学的バイオセンサー
US5089112A (en) 1989-03-20 1992-02-18 Associated Universities, Inc. Electrochemical biosensor based on immobilized enzymes and redox polymers
US4953552A (en) 1989-04-21 1990-09-04 Demarzo Arthur P Blood glucose monitoring system
JP2752429B2 (ja) 1989-04-27 1998-05-18 株式会社クラレ レセプタが固定された細径管およびレセプタの固定方法
EP0396788A1 (en) 1989-05-08 1990-11-14 Dräger Nederland B.V. Process and sensor for measuring the glucose content of glucosecontaining fluids
JPH02310457A (ja) 1989-05-26 1990-12-26 Matsushita Electric Ind Co Ltd バイオセンサ
EP0400918A1 (en) 1989-05-31 1990-12-05 Nakano Vinegar Co., Ltd. Enzyme sensor
US4988341A (en) 1989-06-05 1991-01-29 Eastman Kodak Company Sterilizing dressing device and method for skin puncture
US5198367A (en) 1989-06-09 1993-03-30 Masuo Aizawa Homogeneous amperometric immunoassay
FR2648353B1 (fr) 1989-06-16 1992-03-27 Europhor Sa Sonde de microdialyse
JPH0326956A (ja) 1989-06-24 1991-02-05 Matsushita Electric Works Ltd 電気化学式センサおよびその製造方法
JPH0750058B2 (ja) 1989-06-27 1995-05-31 松下電工株式会社 酵素固定化電極およびその製造方法
CH677149A5 (enExample) 1989-07-07 1991-04-15 Disetronic Ag
US5407431A (en) 1989-07-11 1995-04-18 Med-Design Inc. Intravenous catheter insertion device with retractable needle
US4986271A (en) 1989-07-19 1991-01-22 The University Of New Mexico Vivo refillable glucose sensor
US5431160A (en) 1989-07-19 1995-07-11 University Of New Mexico Miniature implantable refillable glucose sensor and material therefor
US5013161A (en) 1989-07-28 1991-05-07 Becton, Dickinson And Company Electronic clinical thermometer
US5264105A (en) 1989-08-02 1993-11-23 Gregg Brian A Enzyme electrodes
US5320725A (en) 1989-08-02 1994-06-14 E. Heller & Company Electrode and method for the detection of hydrogen peroxide
US5264104A (en) 1989-08-02 1993-11-23 Gregg Brian A Enzyme electrodes
US5262035A (en) 1989-08-02 1993-11-16 E. Heller And Company Enzyme electrodes
US4944299A (en) 1989-08-08 1990-07-31 Siemens-Pacesetter, Inc. High speed digital telemetry system for implantable device
US5101814A (en) 1989-08-11 1992-04-07 Palti Yoram Prof System for monitoring and controlling blood glucose
US5190041A (en) 1989-08-11 1993-03-02 Palti Yoram Prof System for monitoring and controlling blood glucose
US5095904A (en) 1989-09-08 1992-03-17 Cochlear Pty. Ltd. Multi-peak speech procession
US5050612A (en) 1989-09-12 1991-09-24 Matsumura Kenneth N Device for computer-assisted monitoring of the body
JP2517153B2 (ja) 1989-09-21 1996-07-24 松下電器産業株式会社 バイオセンサおよびその製造法
FR2652736A1 (fr) 1989-10-06 1991-04-12 Neftel Frederic Dispositif implantable d'evaluation du taux de glucose.
DE3934299C1 (enExample) 1989-10-13 1990-10-25 Gesellschaft Fuer Biotechnologische Forschung Mbh (Gbf), 3300 Braunschweig, De
EP0429076B1 (en) 1989-11-24 1996-01-31 Matsushita Electric Industrial Co., Ltd. Preparation of biosensor
US5036860A (en) 1989-11-24 1991-08-06 Medical Device Technologies, Inc. Disposable soft tissue biopsy apparatus
US5082550A (en) 1989-12-11 1992-01-21 The United States Of America As Represented By The Department Of Energy Enzyme electrochemical sensor electrode and method of making it
US5140985A (en) 1989-12-11 1992-08-25 Schroeder Jon M Noninvasive blood glucose measuring device
US5985129A (en) 1989-12-14 1999-11-16 The Regents Of The University Of California Method for increasing the service life of an implantable sensor
US5342789A (en) 1989-12-14 1994-08-30 Sensor Technologies, Inc. Method and device for detecting and quantifying glucose in body fluids
CA2069946C (en) 1989-12-15 1999-01-26 Klaus H. Pollmann Redox mediator reagent and biosensor
US4985142A (en) 1989-12-15 1991-01-15 Sundstrand Corporation Quick release filter by-pass valve
US5051688A (en) 1989-12-20 1991-09-24 Rohm Co., Ltd. Crossed coil meter driving device having a plurality of input parameters
US5243696A (en) 1989-12-29 1993-09-07 General Signal Corporation Programmable electronic display for a chart recorder
US5286362A (en) 1990-02-03 1994-02-15 Boehringer Mannheim Gmbh Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor
US5109850A (en) 1990-02-09 1992-05-05 Massachusetts Institute Of Technology Automatic blood monitoring for medication delivery method and apparatus
CA2010670C (en) 1990-02-22 1997-04-01 James H. Dymond Salient pole rotor for a dynamoelectric machine
US5162407A (en) 1990-03-06 1992-11-10 Investors Diversified Capital, Inc. Silicone rubber sealant composition
US5161532A (en) 1990-04-19 1992-11-10 Teknekron Sensor Development Corporation Integral interstitial fluid sensor
US5165407A (en) 1990-04-19 1992-11-24 The University Of Kansas Implantable glucose sensor
DE4014109A1 (de) 1990-05-02 1991-11-07 Siemens Ag Elekrochemische bestimmung der sauerstoffkonzentration
US5250439A (en) 1990-07-19 1993-10-05 Miles Inc. Use of conductive sensors in diagnostic assays
US5202261A (en) 1990-07-19 1993-04-13 Miles Inc. Conductive sensors and their use in diagnostic assays
US5124661A (en) 1990-07-23 1992-06-23 I-Stat Corporation Reusable test unit for simulating electrochemical sensor signals for quality assurance of portable blood analyzer instruments
US5975321A (en) 1990-08-09 1999-11-02 Portola Packaging, Inc. Snap-on, screw-off cap with tamper-evidencing skirt and container neck
CA2089738C (en) 1990-09-28 1997-01-21 Avinash Govind Thombre Dispensing device containing a hydrophobic medium
US5251126A (en) 1990-10-29 1993-10-05 Miles Inc. Diabetes data analysis and interpretation method
US5058592A (en) 1990-11-02 1991-10-22 Whisler G Douglas Adjustable mountable doppler ultrasound transducer device
RU2118116C1 (ru) 1990-12-12 1998-08-27 Шервуд Медикал Кампани Термометр для измерения температуры тела и способ измерения температуры тела пациента (варианты)
US5527288A (en) 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
US5228449A (en) 1991-01-22 1993-07-20 Athanasios G. Christ System and method for detecting out-of-hospital cardiac emergencies and summoning emergency assistance
AU1356792A (en) 1991-01-25 1992-08-27 Markwell Medical Institute, Inc. Implantable biological fluid measuring device
FR2673289B1 (fr) 1991-02-21 1994-06-17 Asulab Sa Capteur de mesure de la quantite d'un composant en solution.
US5262305A (en) 1991-03-04 1993-11-16 E. Heller & Company Interferant eliminating biosensors
US5593852A (en) 1993-12-02 1997-01-14 Heller; Adam Subcutaneous glucose electrode
CA2050057A1 (en) 1991-03-04 1992-09-05 Adam Heller Interferant eliminating biosensors
US5632272A (en) 1991-03-07 1997-05-27 Masimo Corporation Signal processing apparatus
US5469855A (en) 1991-03-08 1995-11-28 Exergen Corporation Continuous temperature monitor
US5135004A (en) 1991-03-12 1992-08-04 Incontrol, Inc. Implantable myocardial ischemia monitor and related method
US5204264A (en) 1991-03-14 1993-04-20 E. I. Du Pont De Nemours And Company Method for validation of calibration standards in an automatic chemical analyzer
GB9107193D0 (en) 1991-04-05 1991-05-22 Wilson Robert Analytical devices
US5238729A (en) 1991-04-05 1993-08-24 Minnesota Mining And Manufacturing Company Sensors based on nanosstructured composite films
US5208154A (en) 1991-04-08 1993-05-04 The United States Of America As Represented By The Department Of Energy Reversibly immobilized biological materials in monolayer films on electrodes
US5192416A (en) 1991-04-09 1993-03-09 New Mexico State University Technology Transfer Corporation Method and apparatus for batch injection analysis
US5293546A (en) 1991-04-17 1994-03-08 Martin Marietta Corporation Oxide coated metal grid electrode structure in display devices
US5122925A (en) 1991-04-22 1992-06-16 Control Products, Inc. Package for electronic components
JP3118015B2 (ja) 1991-05-17 2000-12-18 アークレイ株式会社 バイオセンサーおよびそれを用いた分離定量方法
US5209229A (en) 1991-05-20 1993-05-11 Telectronics Pacing Systems, Inc. Apparatus and method employing plural electrode configurations for cardioversion of atrial fibrillation in an arrhythmia control system
FI88223C (fi) 1991-05-22 1993-04-13 Polar Electro Oy Telemetrisk saendarenhet
US5289497A (en) 1991-05-23 1994-02-22 Interdigital Technology Corporation Broadcast synchronized communication system
JP2816262B2 (ja) 1991-07-09 1998-10-27 工業技術院長 炭素微小センサー電極およびその製造方法
CA2074702C (en) 1991-07-29 1996-11-19 Donald J. Urbas Programmable transponder
US5231988A (en) 1991-08-09 1993-08-03 Cyberonics, Inc. Treatment of endocrine disorders by nerve stimulation
US5284156A (en) 1991-08-30 1994-02-08 M3 Systems, Inc. Automatic tissue sampling apparatus
JPH0572171A (ja) 1991-09-12 1993-03-23 Omron Corp 酵素電極
GB9120144D0 (en) 1991-09-20 1991-11-06 Imperial College A dialysis electrode device
US5234835A (en) 1991-09-26 1993-08-10 C.R. Bard, Inc. Precalibrated fiber optic sensing method
US5322063A (en) 1991-10-04 1994-06-21 Eli Lilly And Company Hydrophilic polyurethane membranes for electrochemical glucose sensors
DK175491D0 (da) 1991-10-18 1991-10-18 Novo Nordisk As Apparat
US5264103A (en) 1991-10-18 1993-11-23 Matsushita Electric Industrial Co., Ltd. Biosensor and a method for measuring a concentration of a substrate in a sample
US5217595A (en) 1991-10-25 1993-06-08 The Yellow Springs Instrument Company, Inc. Electrochemical gas sensor
US5415164A (en) 1991-11-04 1995-05-16 Biofield Corp. Apparatus and method for screening and diagnosing trauma or disease in body tissues
DE4139122C1 (enExample) 1991-11-28 1993-04-08 Fenzlein, Paul-Gerhard, 8500 Nuernberg, De
US5372427A (en) 1991-12-19 1994-12-13 Texas Instruments Incorporated Temperature sensor
US5271815A (en) 1991-12-26 1993-12-21 Via Medical Corporation Method for measuring glucose
US5285792A (en) 1992-01-10 1994-02-15 Physio-Control Corporation System for producing prioritized alarm messages in a medical instrument
US5246867A (en) 1992-01-17 1993-09-21 University Of Maryland At Baltimore Determination and quantification of saccharides by luminescence lifetimes and energy transfer
JP3084877B2 (ja) 1992-01-21 2000-09-04 松下電器産業株式会社 グルコースセンサの製造方法
IL104365A0 (en) 1992-01-31 1993-05-13 Gensia Pharma Method and apparatus for closed loop drug delivery
NL9200207A (nl) 1992-02-05 1993-09-01 Nedap Nv Implanteerbare biomedische sensorinrichting, in het bijzonder voor meting van de glucoseconcentratie.
US5328927A (en) 1992-03-03 1994-07-12 Merck Sharpe & Dohme, Ltd. Hetercyclic compounds, processes for their preparation and pharmaceutical compositions containing them
ZA931077B (en) 1992-03-05 1994-01-04 Qualcomm Inc Apparatus and method for reducing message collision between mobile stations simultaneously accessing a base station in a cdma cellular communications system
DE69319771T2 (de) 1992-03-31 1999-04-22 Dai Nippon Printing Co., Ltd., Tokio/Tokyo Immobilisierte Enzym-Elektrode, Zusammensetzung zu ihrer Herstellung und elektrisch leitfähige Enzyme
EP0636009B1 (en) 1992-04-03 2000-11-29 Micromedical Industries Limited system for physiological monitoring
US5263244A (en) 1992-04-17 1993-11-23 Gould Inc. Method of making a flexible printed circuit sensor assembly for detecting optical pulses
IL101720A (en) 1992-04-29 1998-09-24 Mali Tech Ltd Needle for syringe or the like
US5318583A (en) 1992-05-05 1994-06-07 Ryder International Corporation Lancet actuator mechanism
US5711001A (en) 1992-05-08 1998-01-20 Motorola, Inc. Method and circuit for acquisition by a radio receiver
US6785568B2 (en) 1992-05-18 2004-08-31 Non-Invasive Technology Inc. Transcranial examination of the brain
GB9211402D0 (en) 1992-05-29 1992-07-15 Univ Manchester Sensor devices
US5333615A (en) 1992-06-22 1994-08-02 William Craelius Apparatus for digitally recording and analyzing electrocardial and other bioelectric signals
DK95792A (da) 1992-07-24 1994-01-25 Radiometer As Sensor til non-invasiv, in vivo bestemmelse af en analyt og blodgennemstrømning
PL169210B1 (pl) 1992-08-03 1996-06-28 Przed Zagraniczne Htl Przyrzad do nakluwania PL
US5267963A (en) 1992-08-21 1993-12-07 Nicholas Bachynsky Medication injection device
US6283761B1 (en) 1992-09-08 2001-09-04 Raymond Anthony Joao Apparatus and method for processing and/or for providing healthcare information and/or healthcare-related information
US5400782A (en) 1992-10-07 1995-03-28 Graphic Controls Corporation Integral medical electrode including a fusible conductive substrate
CA2107852C (en) 1992-10-09 2004-09-07 Gerald Leigh Metcalf Trocar
US5421816A (en) 1992-10-14 1995-06-06 Endodermic Medical Technologies Company Ultrasonic transdermal drug delivery system
US5387327A (en) 1992-10-19 1995-02-07 Duquesne University Of The Holy Ghost Implantable non-enzymatic electrochemical glucose sensor
US5320098A (en) 1992-10-20 1994-06-14 Sun Microsystems, Inc. Optical transdermal link
WO1994010553A1 (en) 1992-10-23 1994-05-11 Optex Biomedical, Inc. Fibre-optic probe for the measurement of fluid parameters
US5601435A (en) 1994-11-04 1997-02-11 Intercare Method and apparatus for interactively monitoring a physiological condition and for interactively providing health related information
US5918603A (en) 1994-05-23 1999-07-06 Health Hero Network, Inc. Method for treating medical conditions using a microprocessor-based video game
US5956501A (en) 1997-01-10 1999-09-21 Health Hero Network, Inc. Disease simulation system and method
US20010011224A1 (en) 1995-06-07 2001-08-02 Stephen James Brown Modular microprocessor-based health monitoring system
US5899855A (en) 1992-11-17 1999-05-04 Health Hero Network, Inc. Modular microprocessor-based health monitoring system
US20030212579A1 (en) 2002-05-08 2003-11-13 Brown Stephen J. Remote health management system
ZA938555B (en) 1992-11-23 1994-08-02 Lilly Co Eli Technique to improve the performance of electrochemical sensors
US5410326A (en) 1992-12-04 1995-04-25 Goldstein; Steven W. Programmable remote control device for interacting with a plurality of remotely controlled devices
DK148592D0 (da) 1992-12-10 1992-12-10 Novo Nordisk As Apparat
JPH06190050A (ja) 1992-12-22 1994-07-12 Mitsubishi Cable Ind Ltd 触覚機能を具備する体内挿入用医療器具
US5499243A (en) 1993-01-22 1996-03-12 Hall; Dennis R. Method and apparatus for coordinating transfer of information between a base station and a plurality of radios
US5299571A (en) 1993-01-22 1994-04-05 Eli Lilly And Company Apparatus and method for implantation of sensors
FR2701117B1 (fr) 1993-02-04 1995-03-10 Asulab Sa Système de mesures électrochimiques à capteur multizones, et son application au dosage du glucose.
GB9304306D0 (en) 1993-03-03 1993-04-21 Univ Alberta Glucose sensor
US5600301A (en) 1993-03-11 1997-02-04 Schrader Automotive Inc. Remote tire pressure monitoring system employing coded tire identification and radio frequency transmission, and enabling recalibration upon tire rotation or replacement
US5400794A (en) 1993-03-19 1995-03-28 Gorman; Peter G. Biomedical response monitor and technique using error correction
US5394877A (en) 1993-04-01 1995-03-07 Axon Medical, Inc. Ultrasound medical diagnostic device having a coupling medium providing self-adherence to a patient
DE59408870D1 (de) 1993-04-23 1999-12-09 Roche Diagnostics Gmbh System zur Bevorratung und Zurverfügungstellung von Testelementen
US5558638A (en) 1993-04-30 1996-09-24 Healthdyne, Inc. Patient monitor and support system
US5540664A (en) 1993-05-27 1996-07-30 Washington Biotech Corporation Reloadable automatic or manual emergency injection system
DE4318519C2 (de) 1993-06-03 1996-11-28 Fraunhofer Ges Forschung Elektrochemischer Sensor
AU7210894A (en) 1993-06-25 1995-01-17 Xircom, Inc. Virtual carrier detection for wireless local area network with distributed control
JPH0772585A (ja) 1993-07-06 1995-03-17 Fuji Photo Film Co Ltd ポリエステル支持体
US5575563A (en) 1993-07-15 1996-11-19 Chiu; Job Multiusage thermometer
US5384547A (en) 1993-08-02 1995-01-24 Motorola, Inc. Apparatus and method for attenuating a multicarrier input signal of a linear device
JP2979933B2 (ja) 1993-08-03 1999-11-22 セイコーエプソン株式会社 脈波解析装置
JP3252179B2 (ja) 1993-08-06 2002-01-28 カシオ計算機株式会社 酵素センサ
US5402780A (en) 1993-09-02 1995-04-04 Faasse, Jr.; Adrian L. Medical electrode with offset contact stud
DE4329898A1 (de) 1993-09-04 1995-04-06 Marcus Dr Besson Kabelloses medizinisches Diagnose- und Überwachungsgerät
US5438983A (en) 1993-09-13 1995-08-08 Hewlett-Packard Company Patient alarm detection using trend vector analysis
US5582184A (en) 1993-10-13 1996-12-10 Integ Incorporated Interstitial fluid collection and constituent measurement
US5885211A (en) 1993-11-15 1999-03-23 Spectrix, Inc. Microporation of human skin for monitoring the concentration of an analyte
US6336269B1 (en) 1993-11-16 2002-01-08 Benjamin N. Eldridge Method of fabricating an interconnection element
US5997501A (en) 1993-11-18 1999-12-07 Elan Corporation, Plc Intradermal drug delivery device
US5791344A (en) 1993-11-19 1998-08-11 Alfred E. Mann Foundation For Scientific Research Patient monitoring system
US5497772A (en) 1993-11-19 1996-03-12 Alfred E. Mann Foundation For Scientific Research Glucose monitoring system
FR2713372B1 (fr) 1993-12-01 1996-03-01 Neopost Ind Dispositif de protection thermique pour appareil électronique sécurisé, notamment machine à affranchir.
JPH07182462A (ja) 1993-12-22 1995-07-21 Toshiba Corp 文字認識装置及び方法
US6022315A (en) 1993-12-29 2000-02-08 First Opinion Corporation Computerized medical diagnostic and treatment advice system including network access
US5724968A (en) 1993-12-29 1998-03-10 First Opinion Corporation Computerized medical diagnostic system including meta function
US5589326A (en) 1993-12-30 1996-12-31 Boehringer Mannheim Corporation Osmium-containing redox mediator
US5320715A (en) 1994-01-14 1994-06-14 Lloyd Berg Separation of 1-pentanol from cyclopentanol by extractive distillation
DE4401400A1 (de) 1994-01-19 1995-07-20 Ernst Prof Dr Pfeiffer Verfahren und Anordnung zur kontinuierlichen Überwachung der Konzentration eines Metaboliten
US5437999A (en) 1994-02-22 1995-08-01 Boehringer Mannheim Corporation Electrochemical sensor
US5543326A (en) 1994-03-04 1996-08-06 Heller; Adam Biosensor including chemically modified enzymes
US5506458A (en) 1994-03-04 1996-04-09 Quantum Corporation Low cost permanent magnet disk spindle motor
US5536249A (en) 1994-03-09 1996-07-16 Visionary Medical Products, Inc. Pen-type injector with a microprocessor and blood characteristic monitor
US5390671A (en) 1994-03-15 1995-02-21 Minimed Inc. Transcutaneous sensor insertion set
US5391250A (en) 1994-03-15 1995-02-21 Minimed Inc. Method of fabricating thin film sensors
AU2200895A (en) 1994-04-04 1995-10-23 Motorola, Inc. Method and apparatus for activating and accessing remote meter interface devices
US5484403A (en) 1994-04-05 1996-01-16 Avid Marketing, Inc. Hypodermic syringe for implanting solid objects
GB9407137D0 (en) 1994-04-11 1994-06-01 Amp Gmbh Electrical connector suction platform for facilitating picking
US5609575A (en) 1994-04-11 1997-03-11 Graseby Medical Limited Infusion pump and method with dose-rate calculation
JP3061351B2 (ja) 1994-04-25 2000-07-10 松下電器産業株式会社 特定化合物の定量法およびその装置
US5569186A (en) 1994-04-25 1996-10-29 Minimed Inc. Closed loop infusion pump system with removable glucose sensor
DE4415896A1 (de) 1994-05-05 1995-11-09 Boehringer Mannheim Gmbh Analysesystem zur Überwachung der Konzentration eines Analyten im Blut eines Patienten
US5545191A (en) 1994-05-06 1996-08-13 Alfred E. Mann Foundation For Scientific Research Method for optimally positioning and securing the external unit of a transcutaneous transducer of the skin of a living body
US5482473A (en) 1994-05-09 1996-01-09 Minimed Inc. Flex circuit connector
US5472317A (en) 1994-06-03 1995-12-05 Minimed Inc. Mounting clip for a medication infusion pump
US5494562A (en) 1994-06-27 1996-02-27 Ciba Corning Diagnostics Corp. Electrochemical sensors
US5809417A (en) 1994-07-05 1998-09-15 Lucent Technologies Inc. Cordless telephone arranged for operating with multiple portable units in a frequency hopping system
US6123715A (en) 1994-07-08 2000-09-26 Amplatz; Curtis Method of forming medical devices; intravascular occlusion devices
US5549568A (en) 1994-08-22 1996-08-27 Shields; Jack W. Elastomeric needle shield and hub-cap
US5798961A (en) 1994-08-23 1998-08-25 Emc Corporation Non-volatile memory module
US5462051A (en) 1994-08-31 1995-10-31 Colin Corporation Medical communication system
US6213972B1 (en) 1994-09-13 2001-04-10 Alaris Medical Systems, Inc. Fluid flow resistance monitoring system
US7027859B1 (en) 1994-09-26 2006-04-11 Alza Corporation Electrotransport delivery device having improved safety and reduced abuse potential
US5549115A (en) 1994-09-28 1996-08-27 Heartstream, Inc. Method and apparatus for gathering event data using a removable data storage medium and clock
US5724030A (en) 1994-10-13 1998-03-03 Bio Medic Data Systems, Inc. System monitoring reprogrammable implantable transponder
CA2159052C (en) 1994-10-28 2007-03-06 Rainer Alex Injection device
US5516832A (en) 1994-11-03 1996-05-14 Dow Corning Corporation Curable silicone rubber composition
IE72524B1 (en) 1994-11-04 1997-04-23 Elan Med Tech Analyte-controlled liquid delivery device and analyte monitor
US5919141A (en) 1994-11-15 1999-07-06 Life Sensing Instrument Company, Inc. Vital sign remote monitoring device
JP2913372B2 (ja) 1994-12-16 1999-06-28 株式会社コーテックス 係止片取付機用中空針
US5632557A (en) 1994-12-16 1997-05-27 Weed Instrument Company, Inc. Modular temperature sensing apparatus
US5562713A (en) 1995-01-18 1996-10-08 Pacesetter, Inc. Bidirectional telemetry apparatus and method for implantable device
ATE160079T1 (de) 1995-02-04 1997-11-15 Baumann & Haldi Sa Einzelne anordnung zur messung, verarbeitung und übertragung von im wesentlichen physiologischen parametern
US5636640A (en) 1995-02-06 1997-06-10 Volunteers For Medical Engineering Liquid sampling and test apparatus
US5551427A (en) 1995-02-13 1996-09-03 Altman; Peter A. Implantable device for the effective elimination of cardiac arrhythmogenic sites
US5586553A (en) 1995-02-16 1996-12-24 Minimed Inc. Transcutaneous sensor insertion set
JP3297971B2 (ja) 1995-02-16 2002-07-02 オムロン株式会社 電子血圧計
US5568806A (en) 1995-02-16 1996-10-29 Minimed Inc. Transcutaneous sensor insertion set
US5564434A (en) 1995-02-27 1996-10-15 Medtronic, Inc. Implantable capacitive absolute pressure and temperature sensor
US5651869A (en) 1995-02-28 1997-07-29 Matsushita Electric Industrial Co., Ltd. Biosensor
US5596150A (en) 1995-03-08 1997-01-21 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Capacitance probe for fluid flow and volume measurements
JPH08247987A (ja) 1995-03-15 1996-09-27 Omron Corp 携帯型測定器
US5582697A (en) 1995-03-17 1996-12-10 Matsushita Electric Industrial Co., Ltd. Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same
US5788833A (en) 1995-03-27 1998-08-04 California Institute Of Technology Sensors for detecting analytes in fluids
US5786439A (en) 1996-10-24 1998-07-28 Minimed Inc. Hydrophilic, swellable coatings for biosensors
JPH08285814A (ja) 1995-04-14 1996-11-01 Casio Comput Co Ltd バイオセンサ
JPH08285815A (ja) 1995-04-18 1996-11-01 Casio Comput Co Ltd バイオセンサ
US5752512A (en) 1995-05-10 1998-05-19 Massachusetts Institute Of Technology Apparatus and method for non-invasive blood analyte measurement
US5628310A (en) 1995-05-19 1997-05-13 Joseph R. Lakowicz Method and apparatus to perform trans-cutaneous analyte monitoring
US5567302A (en) 1995-06-07 1996-10-22 Molecular Devices Corporation Electrochemical system for rapid detection of biochemical agents that catalyze a redox potential change
US5638832A (en) 1995-06-07 1997-06-17 Interval Research Corporation Programmable subcutaneous visible implant
US5743262A (en) 1995-06-07 1998-04-28 Masimo Corporation Blood glucose monitoring system
US5584813A (en) 1995-06-07 1996-12-17 Minimed Inc. Subcutaneous injection set
US5995860A (en) 1995-07-06 1999-11-30 Thomas Jefferson University Implantable sensor and system for measurement and control of blood constituent levels
JP3548919B2 (ja) 1995-07-07 2004-08-04 カシオ計算機株式会社 バイオセンサ
JP2819260B2 (ja) 1995-07-11 1998-10-30 株式会社朋友メディカル カテーテル延長チューブ
US5555190A (en) 1995-07-12 1996-09-10 Micro Motion, Inc. Method and apparatus for adaptive line enhancement in Coriolis mass flow meter measurement
US5536259A (en) * 1995-07-28 1996-07-16 Medisystems Technology Corp Hypodermic cannula
US5581206A (en) 1995-07-28 1996-12-03 Micron Quantum Devices, Inc. Power level detection circuit
US6001065A (en) 1995-08-02 1999-12-14 Ibva Technologies, Inc. Method and apparatus for measuring and analyzing physiological signals for active or passive control of physical and virtual spaces and the contents therein
US5766131A (en) 1995-08-04 1998-06-16 Seiko Epson Corporation Pulse-wave measuring apparatus
US7016713B2 (en) 1995-08-09 2006-03-21 Inlight Solutions, Inc. Non-invasive determination of direction and rate of change of an analyte
US5749656A (en) 1995-08-11 1998-05-12 General Motors Corporation Thermal probe assembly with mold-over crimp sensor packaging
DE19530376C2 (de) 1995-08-18 1999-09-02 Fresenius Ag Biosensor
US5682233A (en) 1995-09-08 1997-10-28 Integ, Inc. Interstitial fluid sampler
IE77523B1 (en) 1995-09-11 1997-12-17 Elan Med Tech Medicament delivery device
US5735273A (en) 1995-09-12 1998-04-07 Cygnus, Inc. Chemical signal-impermeable mask
DE19534887B4 (de) 1995-09-20 2004-04-15 Robert Bosch Gmbh Temperaturfühler
US5628890A (en) 1995-09-27 1997-05-13 Medisense, Inc. Electrochemical sensor
US5669890A (en) 1995-10-03 1997-09-23 Ivy Laboratories, Inc. Metal tip attachment for plastic needles
JPH09101280A (ja) 1995-10-05 1997-04-15 Casio Comput Co Ltd バイオセンサ
US5972199A (en) 1995-10-11 1999-10-26 E. Heller & Company Electrochemical analyte sensors using thermostable peroxidase
US5665222A (en) 1995-10-11 1997-09-09 E. Heller & Company Soybean peroxidase electrochemical sensor
ES2121525B1 (es) 1995-10-11 1999-09-16 Krebs & Co Ag Krebs & Co Sa Kr Sistema de produccion de sal por evaporacion forzada.
US5741211A (en) 1995-10-26 1998-04-21 Medtronic, Inc. System and method for continuous monitoring of diabetes-related blood constituents
US5748103A (en) 1995-11-13 1998-05-05 Vitalcom, Inc. Two-way TDMA telemetry system with power conservation features
US5711861A (en) 1995-11-22 1998-01-27 Ward; W. Kenneth Device for monitoring changes in analyte concentration
ZA9610374B (en) 1995-12-11 1997-06-23 Elan Med Tech Cartridge-based drug delivery device
US5827184A (en) 1995-12-29 1998-10-27 Minnesota Mining And Manufacturing Company Self-packaging bioelectrodes
US5746697A (en) 1996-02-09 1998-05-05 Nellcor Puritan Bennett Incorporated Medical diagnostic apparatus with sleep mode
FI960636A7 (fi) 1996-02-12 1997-08-13 Nokia Corp Menetelmä potilaan terveydentilan valvomiseksi
FI118509B (fi) 1996-02-12 2007-12-14 Nokia Oyj Menetelmä ja laitteisto potilaan veren glukoosipitoisuuden ennustamiseksi
US5708247A (en) 1996-02-14 1998-01-13 Selfcare, Inc. Disposable glucose test strips, and methods and compositions for making same
AU2052997A (en) 1996-02-23 1997-09-10 Diasense, Inc. Method and apparatus for non-invasive blood glucose sensing
US5833603A (en) 1996-03-13 1998-11-10 Lipomatrix, Inc. Implantable biosensing transponder
US5673322A (en) 1996-03-22 1997-09-30 Bell Communications Research, Inc. System and method for providing protocol translation and filtering to access the world wide web from wireless or low-bandwidth networks
US6533805B1 (en) 1996-04-01 2003-03-18 General Surgical Innovations, Inc. Prosthesis and method for deployment within a body lumen
EP0898468B1 (en) 1996-04-08 2003-10-15 Medtronic, Inc. Method of fixing a physiologic mitral valve bioprosthesis
US5733262A (en) 1996-04-18 1998-03-31 Paul; Kamaljit S. Blood vessel cannulation device
JP3627373B2 (ja) 1996-04-23 2005-03-09 カシオ計算機株式会社 バイオセンサ
FR2748171B1 (fr) 1996-04-30 1998-07-17 Motorola Inc Procede de generation d'un signal d'horloge pour une utilisation dans un recepteur de donnees, generateur d'horloge, recepteur de donnees et systeme d'acces telecommande pour vehicules
DE19618597B4 (de) 1996-05-09 2005-07-21 Institut für Diabetestechnologie Gemeinnützige Forschungs- und Entwicklungsgesellschaft mbH an der Universität Ulm Verfahren zur Bestimmung der Konzentration von Gewebeglucose
US6130602A (en) 1996-05-13 2000-10-10 Micron Technology, Inc. Radio frequency data communications device
EP0906062B1 (en) 1996-05-17 2007-12-26 Roche Diagnostics Operations, Inc. Body fluid sampling device
US5951492A (en) 1996-05-17 1999-09-14 Mercury Diagnostics, Inc. Methods and apparatus for sampling and analyzing body fluid
US5879311A (en) 1996-05-17 1999-03-09 Mercury Diagnostics, Inc. Body fluid sampling device and methods of use
EP1579814A3 (en) 1996-05-17 2006-06-14 Roche Diagnostics Operations, Inc. Methods and apparatus for sampling and analyzing body fluid
GB2325167B (en) 1996-05-17 2000-05-10 Mercury Diagnostics Inc Blood and interstitial fluid sampling device
DE69739783D1 (de) 1996-05-17 2010-04-08 Roche Diagnostics Operations Vorrichtung zur probenahme von körperflüssigkeiten
US5954685A (en) 1996-05-24 1999-09-21 Cygnus, Inc. Electrochemical sensor with dual purpose electrode
US5613978A (en) 1996-06-04 1997-03-25 Palco Laboratories Adjustable tip for lancet device
US5735285A (en) 1996-06-04 1998-04-07 Data Critical Corp. Method and hand-held apparatus for demodulating and viewing frequency modulated biomedical signals
DK0914178T3 (da) 1996-06-18 2003-04-22 Alza Corp Anordning til forøgelse af transdermal afgivelse eller prøveudtagning af et middel
US5830064A (en) 1996-06-21 1998-11-03 Pear, Inc. Apparatus and method for distinguishing events which collectively exceed chance expectations and thereby controlling an output
JP3581218B2 (ja) 1996-07-03 2004-10-27 株式会社東芝 移動通信端末装置とその携帯電話機並びにデータ端末装置
JP2000515778A (ja) 1996-07-08 2000-11-28 アニマス コーポレーシヨン 体液成分レベルの生体内測定および制御のための埋込可能センサーおよびシステム
US5707502A (en) 1996-07-12 1998-01-13 Chiron Diagnostics Corporation Sensors for measuring analyte concentrations and methods of making same
AU3892297A (en) 1996-07-26 1998-02-20 Ikonos Corporation Sensor for detecting heparin and other analytes
US5733313A (en) 1996-08-01 1998-03-31 Exonix Corporation RF coupled, implantable medical device with rechargeable back-up power source
US6544193B2 (en) 1996-09-04 2003-04-08 Marcio Marc Abreu Noninvasive measurement of chemical substances
US5738220A (en) 1996-09-30 1998-04-14 Pacesetter, Inc. Distal tip protector cap
US6032064A (en) 1996-10-11 2000-02-29 Aspect Medical Systems, Inc. Electrode array system for measuring electrophysiological signals
US5771001A (en) 1996-11-18 1998-06-23 Cobb; Marlon J. Personal alarm system
US5856758A (en) 1996-11-20 1999-01-05 Adtran, Inc. Low distortion driver employing positive feedback for reducing power loss in output impedance that effectively matches the impedance of driven line
US6004278A (en) 1996-12-05 1999-12-21 Mdc Investment Holdings, Inc. Fluid collection device with retractable needle
JPH10170471A (ja) 1996-12-06 1998-06-26 Casio Comput Co Ltd バイオセンサ
US6093156A (en) 1996-12-06 2000-07-25 Abbott Laboratories Method and apparatus for obtaining blood for diagnostic tests
US5964993A (en) 1996-12-19 1999-10-12 Implanted Biosystems Inc. Glucose sensor
US6130623A (en) 1996-12-31 2000-10-10 Lucent Technologies Inc. Encryption for modulated backscatter systems
US5914026A (en) 1997-01-06 1999-06-22 Implanted Biosystems Inc. Implantable sensor employing an auxiliary electrode
US6122351A (en) 1997-01-21 2000-09-19 Med Graph, Inc. Method and system aiding medical diagnosis and treatment
US6607509B2 (en) 1997-12-31 2003-08-19 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
US7329239B2 (en) 1997-02-05 2008-02-12 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
US20070142776A9 (en) 1997-02-05 2007-06-21 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
US5851197A (en) 1997-02-05 1998-12-22 Minimed Inc. Injector for a subcutaneous infusion set
US6093172A (en) 1997-02-05 2000-07-25 Minimed Inc. Injector for a subcutaneous insertion set
ES2184236T3 (es) 1997-02-06 2003-04-01 Therasense Inc Sensor in vitro de analitos de pequeño volumen.
US6054194A (en) 1997-02-11 2000-04-25 Kane; Nathan R. Mathematically optimized family of ultra low distortion bellow fold patterns
US5749907A (en) 1997-02-18 1998-05-12 Pacesetter, Inc. System and method for identifying and displaying medical data which violate programmable alarm conditions
US8555894B2 (en) 1997-02-26 2013-10-15 Alfred E. Mann Foundation For Scientific Research System for monitoring temperature
US6309884B1 (en) 1997-02-26 2001-10-30 Diasense, Inc. Individual calibration of blood glucose for supporting noninvasive self-monitoring blood glucose
US6159147A (en) 1997-02-28 2000-12-12 Qrs Diagnostics, Llc Personal computer card for collection of real-time biological data
US7657297B2 (en) 2004-05-03 2010-02-02 Dexcom, Inc. Implantable analyte sensor
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US6741877B1 (en) 1997-03-04 2004-05-25 Dexcom, Inc. Device and method for determining analyte levels
US7192450B2 (en) 2003-05-21 2007-03-20 Dexcom, Inc. Porous membranes for use with implantable devices
US6558321B1 (en) 1997-03-04 2003-05-06 Dexcom, Inc. Systems and methods for remote monitoring and modulation of medical devices
US9155496B2 (en) 1997-03-04 2015-10-13 Dexcom, Inc. Low oxygen in vivo analyte sensor
US20050033132A1 (en) 1997-03-04 2005-02-10 Shults Mark C. Analyte measuring device
US7899511B2 (en) 2004-07-13 2011-03-01 Dexcom, Inc. Low oxygen in vivo analyte sensor
US6862465B2 (en) 1997-03-04 2005-03-01 Dexcom, Inc. Device and method for determining analyte levels
US6554795B2 (en) 1997-03-06 2003-04-29 Medtronic Ave, Inc. Balloon catheter and method of manufacture
US5959529A (en) 1997-03-07 1999-09-28 Kail, Iv; Karl A. Reprogrammable remote sensor monitoring system
US6699187B2 (en) 1997-03-27 2004-03-02 Medtronic, Inc. System and method for providing remote expert communications and video capabilities for use during a medical procedure
US6270455B1 (en) 1997-03-28 2001-08-07 Health Hero Network, Inc. Networked system for interactive communications and remote monitoring of drug delivery
KR100236035B1 (ko) 1997-03-31 1999-12-15 전주범 Atm 망접속기에서 서브 테이블을 이용하여 가상채널의 대역을 할당하는 방법
US6026321A (en) 1997-04-02 2000-02-15 Suzuki Motor Corporation Apparatus and system for measuring electrical potential variations in human body
US6129666A (en) 1997-04-04 2000-10-10 Altec, Inc. Biomedical electrode
US5942979A (en) 1997-04-07 1999-08-24 Luppino; Richard On guard vehicle safety warning system
US5961451A (en) 1997-04-07 1999-10-05 Motorola, Inc. Noninvasive apparatus having a retaining member to retain a removable biosensor
US5987353A (en) 1997-04-10 1999-11-16 Khatchatrian; Robert G. Diagnostic complex for measurement of the condition of biological tissues and liquids
US6059946A (en) 1997-04-14 2000-05-09 Matsushita Electric Industrial Co., Ltd. Biosensor
US5935224A (en) 1997-04-24 1999-08-10 Microsoft Corporation Method and apparatus for adaptively coupling an external peripheral device to either a universal serial bus port on a computer or hub or a game port on a computer
US6186982B1 (en) 1998-05-05 2001-02-13 Elan Corporation, Plc Subcutaneous drug delivery device with improved filling system
US6085342A (en) 1997-05-06 2000-07-04 Telefonaktiebolaget L M Ericsson (Publ) Electronic system having a chip integrated power-on reset circuit with glitch sensor
US5779665A (en) 1997-05-08 1998-07-14 Minimed Inc. Transdermal introducer assembly
JPH10305016A (ja) 1997-05-08 1998-11-17 Casio Comput Co Ltd 行動情報提供システム
US6558351B1 (en) 1999-06-03 2003-05-06 Medtronic Minimed, Inc. Closed loop system for controlling insulin infusion
US5954643A (en) 1997-06-09 1999-09-21 Minimid Inc. Insertion set for a transcutaneous sensor
US7267665B2 (en) 1999-06-03 2007-09-11 Medtronic Minimed, Inc. Closed loop system for controlling insulin infusion
EP0990151A2 (en) 1997-06-16 2000-04-05 ELAN CORPORATION, Plc Methods of calibrating and testing a sensor for (in vivo) measurement of an analyte and devices for use in such methods
US6056435A (en) 1997-06-24 2000-05-02 Exergen Corporation Ambient and perfusion normalized temperature detector
US5865804A (en) 1997-07-16 1999-02-02 Bachynsky; Nicholas Rotary cam syringe
US6066243A (en) 1997-07-22 2000-05-23 Diametrics Medical, Inc. Portable immediate response medical analyzer having multiple testing modules
US5823802A (en) 1997-07-30 1998-10-20 General Motors Corporation Electrical connector with combination seal and contact member
US6085253A (en) 1997-08-01 2000-07-04 United Video Properties, Inc. System and method for transmitting and receiving data
EP1001701B1 (de) 1997-08-09 2004-10-06 Roche Diagnostics GmbH Analysevorrichtung zur in-vivo-analyse im körper eines patienten
US6232950B1 (en) 1997-08-28 2001-05-15 E Ink Corporation Rear electrode structures for displays
US6731976B2 (en) 1997-09-03 2004-05-04 Medtronic, Inc. Device and method to measure and communicate body parameters
US6764581B1 (en) 1997-09-05 2004-07-20 Abbott Laboratories Electrode with thin working layer
US6071391A (en) 1997-09-12 2000-06-06 Nok Corporation Enzyme electrode structure
DE19836401A1 (de) 1997-09-19 2000-02-17 Salcomp Oy Salo Vorrichtung zum Aufladen von Akkumulatoren
US6117290A (en) 1997-09-26 2000-09-12 Pepex Biomedical, Llc System and method for measuring a bioanalyte such as lactate
US20020013538A1 (en) 1997-09-30 2002-01-31 David Teller Method and apparatus for health signs monitoring
US6149626A (en) 1997-10-03 2000-11-21 Bachynsky; Nicholas Automatic injecting syringe apparatus
US5904671A (en) 1997-10-03 1999-05-18 Navot; Nir Tampon wetness detection system
US5938679A (en) 1997-10-14 1999-08-17 Hewlett-Packard Company Apparatus and method for minimally invasive blood sampling
EP1445910A3 (de) 1997-10-15 2005-03-02 Nokia Corporation Verfahren zum Bereitstellen von Information in einem Kommunikationssystem mittels eines mobilen Telefons
US6736957B1 (en) 1997-10-16 2004-05-18 Abbott Laboratories Biosensor electrode mediators for regeneration of cofactors and process for using
US6088608A (en) 1997-10-20 2000-07-11 Alfred E. Mann Foundation Electrochemical sensor and integrity tests therefor
US6119028A (en) 1997-10-20 2000-09-12 Alfred E. Mann Foundation Implantable enzyme-based monitoring systems having improved longevity due to improved exterior surfaces
FI107080B (fi) 1997-10-27 2001-05-31 Nokia Mobile Phones Ltd Mittauslaite
US6144922A (en) 1997-10-31 2000-11-07 Mercury Diagnostics, Incorporated Analyte concentration information collection and communication system
DE69836979T2 (de) 1997-11-12 2007-11-08 Lightouch Medical, Inc. Verfahren zur nicht invasiven analytenmessung
US6068399A (en) 1997-11-12 2000-05-30 K-Jump Health Co., Ltd. Cost-effective electronic thermometer
KR100258969B1 (ko) 1997-11-20 2000-06-15 윤종용 무선 통신기기의 펌웨어 업그레이드 방법 및 기지국에서의펌웨어 업그레이드 지원방법
US5964718A (en) 1997-11-21 1999-10-12 Mercury Diagnostics, Inc. Body fluid sampling device
US6482176B1 (en) 1997-11-27 2002-11-19 Disetronic Licensing Ag Method and device for controlling the introduction depth of an injection needle
US5971941A (en) 1997-12-04 1999-10-26 Hewlett-Packard Company Integrated system and method for sampling blood and analysis
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
AU737787B2 (en) 1997-12-04 2001-08-30 Roche Diagnostics Operations Inc. Instrument
US6071294A (en) 1997-12-04 2000-06-06 Agilent Technologies, Inc. Lancet cartridge for sampling blood
US7401111B1 (en) 1997-12-04 2008-07-15 Roche Diagnostic Operations, Inc. Instrument setup utility program
US5871494A (en) 1997-12-04 1999-02-16 Hewlett-Packard Company Reproducible lancing for sampling blood
US6579690B1 (en) 1997-12-05 2003-06-17 Therasense, Inc. Blood analyte monitoring through subcutaneous measurement
ATE406935T1 (de) 1997-12-11 2008-09-15 Alza Corp Vorrichtung zur verbesserung des transdermalen flusses von medikamenten
CA2312919C (en) 1997-12-31 2004-12-14 Minimed, Inc. Insertion device for an insertion set and method of using the same
DE69842210D1 (de) 1997-12-31 2011-05-12 Medtronic Minimed Inc Einführvorrichtung Und Einführungssatz
US6097480A (en) 1998-01-27 2000-08-01 Kaplan; Milton Vehicle interlock system
US6804543B2 (en) 1998-02-05 2004-10-12 Hema Metrics, Inc. Sensor for transcutaneous measurement of vascular access blood flow
US6056718A (en) 1998-03-04 2000-05-02 Minimed Inc. Medication infusion set
US6134461A (en) 1998-03-04 2000-10-17 E. Heller & Company Electrochemical analyte
US6103033A (en) 1998-03-04 2000-08-15 Therasense, Inc. Process for producing an electrochemical biosensor
US6024699A (en) 1998-03-13 2000-02-15 Healthware Corporation Systems, methods and computer program products for monitoring, diagnosing and treating medical conditions of remotely located patients
US6197181B1 (en) 1998-03-20 2001-03-06 Semitool, Inc. Apparatus and method for electrolytically depositing a metal on a microelectronic workpiece
US6579231B1 (en) 1998-03-27 2003-06-17 Mci Communications Corporation Personal medical monitoring unit and system
SE9801121D0 (sv) 1998-03-30 1998-03-30 Astra Ab Electrical device
JP3104672B2 (ja) 1998-03-31 2000-10-30 日本電気株式会社 電流検出型センサ素子およびその製造方法
US6091975A (en) 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
US6728560B2 (en) 1998-04-06 2004-04-27 The General Hospital Corporation Non-invasive tissue glucose level monitoring
US6721582B2 (en) 1999-04-06 2004-04-13 Argose, Inc. Non-invasive tissue glucose level monitoring
JPH11296598A (ja) 1998-04-07 1999-10-29 Seizaburo Arita 血糖値の予測システム及び予測方法並びにこの方法を記録した記録媒体
CA2325886C (en) 1998-04-09 2009-07-21 California Institute Of Technology Electronic techniques for analyte detection
GB9808408D0 (en) 1998-04-18 1998-06-17 Owen Mumford Ltd Improvements relating to injection devices
US6091987A (en) 1998-04-29 2000-07-18 Medtronic, Inc. Power consumption reduction in medical devices by employing different supply voltages
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
GB2337122B (en) 1998-05-08 2002-11-13 Medisense Inc Test strip
US6106484A (en) 1998-05-12 2000-08-22 Medical Device Technologies, Inc. Reusable automated biopsy needle handle
DK1077636T3 (da) 1998-05-13 2004-05-24 Cygnus Therapeutic Systems Signalbehandling til måling af fysiologiske analytter
DE69902229T2 (de) 1998-05-13 2003-02-20 Cygnus, Inc. Sammelvorrichtungen für transdermale probennahmesysteme
DE69910003T2 (de) 1998-05-13 2004-04-22 Cygnus, Inc., Redwood City Überwachung physiologischer analyte
DE19821723C2 (de) 1998-05-14 2000-07-06 Disetronic Licensing Ag Katheterkopf für subkutane Verabreichung eines Wirkstoffs
US6302855B1 (en) 1998-05-20 2001-10-16 Novo Nordisk A/S Medical apparatus for use by a patient for medical self treatment of diabetes
US6121611A (en) 1998-05-20 2000-09-19 Molecular Imaging Corporation Force sensing probe for scanning probe microscopy
TW406018B (en) 1998-05-21 2000-09-21 Elan Corp Plc Improved adhesive system for medical devices
US6837885B2 (en) 1998-05-22 2005-01-04 Scimed Life Systems, Inc. Surgical probe for supporting inflatable therapeutic devices in contact with tissue in or around body orifices and within tumors
US5951582A (en) 1998-05-22 1999-09-14 Specialized Health Products, Inc. Lancet apparatus and methods
GB9812472D0 (en) 1998-06-11 1998-08-05 Owen Mumford Ltd A dose setting device for medical injectors
JP2000031951A (ja) 1998-07-15 2000-01-28 Fujitsu Ltd バースト同期回路
US6223283B1 (en) 1998-07-17 2001-04-24 Compaq Computer Corporation Method and apparatus for identifying display monitor functionality and compatibility
US6493069B1 (en) 1998-07-24 2002-12-10 Terumo Kabushiki Kaisha Method and instrument for measuring blood sugar level
EP0976415B1 (en) 1998-07-31 2005-05-11 Becton, Dickinson and Company A needle shield for a prefillable syringe
US6458109B1 (en) 1998-08-07 2002-10-01 Hill-Rom Services, Inc. Wound treatment apparatus
US5993423A (en) 1998-08-18 1999-11-30 Choi; Soo Bong Portable automatic syringe device and injection needle unit thereof
US6248067B1 (en) 1999-02-05 2001-06-19 Minimed Inc. Analyte sensor and holter-type monitor system and method of using the same
US6558320B1 (en) 2000-01-20 2003-05-06 Medtronic Minimed, Inc. Handheld personal data assistant (PDA) with a medical device and method of using the same
US6554798B1 (en) 1998-08-18 2003-04-29 Medtronic Minimed, Inc. External infusion device with remote programming, bolus estimator and/or vibration alarm capabilities
US6304766B1 (en) 1998-08-26 2001-10-16 Sensors For Medicine And Science Optical-based sensing devices, especially for in-situ sensing in humans
US6359270B1 (en) 1998-09-04 2002-03-19 Ncr Corporation Communications module mounting for domestic appliance
US7536478B2 (en) 1998-09-11 2009-05-19 Rpx-Lv Acquisition Llc Method and apparatus for opening and launching a web browser in response to an audible signal
KR20000019716A (ko) 1998-09-15 2000-04-15 박호군 바이오플라보노이드 화합물을 포함하는 혈당 강하용 조성물
US6740518B1 (en) 1998-09-17 2004-05-25 Clinical Micro Sensors, Inc. Signal detection techniques for the detection of analytes
US5951521A (en) 1998-09-25 1999-09-14 Minimed Inc. Subcutaneous implantable sensor set having the capability to remove deliver fluids to an insertion site
US6254586B1 (en) 1998-09-25 2001-07-03 Minimed Inc. Method and kit for supplying a fluid to a subcutaneous placement site
US6402689B1 (en) 1998-09-30 2002-06-11 Sicel Technologies, Inc. Methods, systems, and associated implantable devices for dynamic monitoring of physiological and biological properties of tumors
DK1102559T3 (da) 1998-09-30 2003-09-29 Cygnus Therapeutic Systems Fremgangsmåde og anordning til forudsigelse af fysiologiske værdier
US6338790B1 (en) 1998-10-08 2002-01-15 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
US6591125B1 (en) 2000-06-27 2003-07-08 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
US20060202859A1 (en) 1998-10-08 2006-09-14 Mastrototaro John J Telemetered characteristic monitor system and method of using the same
EP1119285A1 (en) 1998-10-08 2001-08-01 Minimed Inc. Telemetered characteristic monitor system
US5948006A (en) 1998-10-14 1999-09-07 Advanced Bionics Corporation Transcutaneous transmission patch
US6496729B2 (en) 1998-10-28 2002-12-17 Medtronic, Inc. Power consumption reduction in medical devices employing multiple supply voltages and clock frequency control
WO2000025661A1 (en) 1998-11-03 2000-05-11 Shell, Allan, Michael Hand held physiological signal acquisition device
CA2351734A1 (en) 1998-11-20 2000-06-02 University Of Connecticut Generic integrated implantable potentiostat telemetry unit for electrochemical sensors
USD431864S (en) * 1998-11-24 2000-10-10 Becton Dickinson And Company Tamper evident cap for a tip cap
WO2000033072A2 (en) 1998-11-30 2000-06-08 Abbott Laboratories Analyte test instrument having improved calibration and communication processes
US6773671B1 (en) 1998-11-30 2004-08-10 Abbott Laboratories Multichemistry measuring device and test strips
US6022368A (en) 1998-11-30 2000-02-08 Gavronsky; Stas Acupuncture method and device
EP1437674B2 (en) 1998-11-30 2011-11-23 Novo Nordisk A/S A method for assisting a user in a medical self treatment
US6540672B1 (en) 1998-12-09 2003-04-01 Novo Nordisk A/S Medical system and a method of controlling the system for use by a patient for medical self treatment
US6161095A (en) 1998-12-16 2000-12-12 Health Hero Network, Inc. Treatment regimen compliance and efficacy with feedback
ATE543442T1 (de) 1998-12-31 2012-02-15 Kensey Nash Corp Gewebebefestigungsvorrichtungen
US6433728B1 (en) 1999-01-22 2002-08-13 Lear Automotive Dearborn, Inc. Integrally molded remote entry transmitter
US6561978B1 (en) 1999-02-12 2003-05-13 Cygnus, Inc. Devices and methods for frequent measurement of an analyte present in a biological system
JP2002537031A (ja) 1999-02-18 2002-11-05 バイオバルブ テクノロジーズ インコーポレイテッド 電気活性な細孔
US6197040B1 (en) 1999-02-23 2001-03-06 Lifescan, Inc. Lancing device having a releasable connector
US6424847B1 (en) 1999-02-25 2002-07-23 Medtronic Minimed, Inc. Glucose monitor calibration methods
AU3245500A (en) 1999-02-25 2000-09-14 Minimed, Inc. Test plug and cable for a glucose monitor
US6360888B1 (en) 1999-02-25 2002-03-26 Minimed Inc. Glucose sensor package system
US6237394B1 (en) 1999-02-25 2001-05-29 Redwood Microsystems, Inc. Apparatus and method for correcting drift in a sensor
US8103325B2 (en) 1999-03-08 2012-01-24 Tyco Healthcare Group Lp Method and circuit for storing and providing historical physiological data
US6132449A (en) 1999-03-08 2000-10-17 Agilent Technologies, Inc. Extraction and transportation of blood for analysis
US6959211B2 (en) 1999-03-10 2005-10-25 Optiscan Biomedical Corp. Device for capturing thermal spectra from tissue
AU4063100A (en) 1999-04-01 2000-10-23 University Of Connecticut, The Optical glucose sensor apparatus and method
GB9907815D0 (en) 1999-04-06 1999-06-02 Univ Cambridge Tech Implantable sensor
CA2366760A1 (en) 1999-04-07 2000-10-12 John T. Kilcoyne Implantable monitoring probe
US6285897B1 (en) 1999-04-07 2001-09-04 Endonetics, Inc. Remote physiological monitoring system
US6231531B1 (en) * 1999-04-09 2001-05-15 Agilent Technologies, Inc. Apparatus and method for minimizing pain perception
US6416471B1 (en) 1999-04-15 2002-07-09 Nexan Limited Portable remote patient telemonitoring system
US6494829B1 (en) 1999-04-15 2002-12-17 Nexan Limited Physiological sensor array
US6200265B1 (en) 1999-04-16 2001-03-13 Medtronic, Inc. Peripheral memory patch and access method for use with an implantable medical device
US6192891B1 (en) 1999-04-26 2001-02-27 Becton Dickinson And Company Integrated system including medication delivery pen, blood monitoring device, and lancer
FR2793021B1 (fr) 1999-04-30 2001-08-03 Siemens Automotive Sa Capteur de temperature et procede de fabrication d'un tel capteur
US6669663B1 (en) 1999-04-30 2003-12-30 Medtronic, Inc. Closed loop medicament pump
US6514689B2 (en) 1999-05-11 2003-02-04 M-Biotech, Inc. Hydrogel biosensor
US6359444B1 (en) 1999-05-28 2002-03-19 University Of Kentucky Research Foundation Remote resonant-circuit analyte sensing apparatus with sensing structure and associated method of sensing
US6546268B1 (en) 1999-06-02 2003-04-08 Ball Semiconductor, Inc. Glucose sensor
US6312378B1 (en) 1999-06-03 2001-11-06 Cardiac Intelligence Corporation System and method for automated collection and analysis of patient information retrieved from an implantable medical device for remote patient care
US7806886B2 (en) 1999-06-03 2010-10-05 Medtronic Minimed, Inc. Apparatus and method for controlling insulin infusion with state variable feedback
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6298255B1 (en) 1999-06-09 2001-10-02 Aspect Medical Systems, Inc. Smart electrophysiological sensor system with automatic authentication and validation and an interface for a smart electrophysiological sensor system
EP1200905B1 (de) 1999-06-10 2016-08-24 Koninklijke Philips N.V. Erkennung eines nutzsignals in einem messsignal
GB2351153B (en) 1999-06-18 2003-03-26 Abbott Lab Electrochemical sensor for analysis of liquid samples
US6423035B1 (en) 1999-06-18 2002-07-23 Animas Corporation Infusion pump with a sealed drive mechanism and improved method of occlusion detection
AU5747100A (en) 1999-06-18 2001-01-09 Therasense, Inc. Mass transport limited in vivo analyte sensor
US7522878B2 (en) 1999-06-21 2009-04-21 Access Business Group International Llc Adaptive inductive power supply with communication
US6368274B1 (en) 1999-07-01 2002-04-09 Medtronic Minimed, Inc. Reusable analyte sensor site and method of using the same
US6168606B1 (en) * 1999-11-10 2001-01-02 Palco Labs, Inc. Single-use lancet device
US6804558B2 (en) 1999-07-07 2004-10-12 Medtronic, Inc. System and method of communicating between an implantable medical device and a remote computer system or health care provider
US6413393B1 (en) 1999-07-07 2002-07-02 Minimed, Inc. Sensor including UV-absorbing polymer and method of manufacture
US6514460B1 (en) 1999-07-28 2003-02-04 Abbott Laboratories Luminous glucose monitoring device
DE19935165A1 (de) 1999-07-28 2001-02-01 Roche Diagnostics Gmbh Verfahren und Anordnung zur Konzentrationsbestimmung von Glucose in einer Körperflüssigkeit
US6471689B1 (en) 1999-08-16 2002-10-29 Thomas Jefferson University Implantable drug delivery catheter system with capillary interface
US6923763B1 (en) 1999-08-23 2005-08-02 University Of Virginia Patent Foundation Method and apparatus for predicting the risk of hypoglycemia
US7113821B1 (en) 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery
US6608562B1 (en) 1999-08-31 2003-08-19 Denso Corporation Vital signal detecting apparatus
AU766573B2 (en) 1999-09-02 2003-10-16 Snap Pak Industries (Aust) Pty Ltd Dispensing sachet by bending and method of sachet manufacture
US6102896A (en) † 1999-09-08 2000-08-15 Cambridge Biostability Limited Disposable injector device
AT408182B (de) 1999-09-17 2001-09-25 Schaupp Lukas Dipl Ing Dr Tech Einrichtung zur in vivo-messung von grössen in lebenden organismen
EP1217942A1 (en) 1999-09-24 2002-07-03 Healthetech, Inc. Physiological monitor and associated computation, display and communication unit
US6767440B1 (en) 2001-04-24 2004-07-27 Roche Diagnostics Corporation Biosensor
US6645359B1 (en) 2000-10-06 2003-11-11 Roche Diagnostics Corporation Biosensor
US6662439B1 (en) 1999-10-04 2003-12-16 Roche Diagnostics Corporation Laser defined features for patterned laminates and electrodes
US7276146B2 (en) 2001-11-16 2007-10-02 Roche Diagnostics Operations, Inc. Electrodes, methods, apparatuses comprising micro-electrode arrays
US7073246B2 (en) 1999-10-04 2006-07-11 Roche Diagnostics Operations, Inc. Method of making a biosensor
US6294997B1 (en) 1999-10-04 2001-09-25 Intermec Ip Corp. RFID tag having timing and environment modules
US20050103624A1 (en) 1999-10-04 2005-05-19 Bhullar Raghbir S. Biosensor and method of making
WO2001028495A2 (en) 1999-10-08 2001-04-26 Healthetech, Inc. Indirect calorimeter for weight control
DE19948759A1 (de) 1999-10-09 2001-04-12 Roche Diagnostics Gmbh Blutlanzettenvorrichtung zur Entnahme von Blut für Diagnosezwecke
JP4210782B2 (ja) 1999-10-13 2009-01-21 アークレイ株式会社 採血位置表示具
US6283982B1 (en) 1999-10-19 2001-09-04 Facet Technologies, Inc. Lancing device and method of sample collection
US6593356B2 (en) 1999-10-20 2003-07-15 Bristol-Myers Squibb Pharma Company Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents
US6616819B1 (en) 1999-11-04 2003-09-09 Therasense, Inc. Small volume in vitro analyte sensor and methods
US20060091006A1 (en) 1999-11-04 2006-05-04 Yi Wang Analyte sensor with insertion monitor, and methods
JP3985022B2 (ja) 1999-11-08 2007-10-03 アークレイ株式会社 体液測定装置、およびこの体液測定装置に挿着して使用する挿着体
US6605201B1 (en) 1999-11-15 2003-08-12 Therasense, Inc. Transition metal complexes with bidentate ligand having an imidazole ring and sensor constructed therewith
US6291200B1 (en) 1999-11-17 2001-09-18 Agentase, Llc Enzyme-containing polymeric sensors
US6925393B1 (en) 1999-11-18 2005-08-02 Roche Diagnostics Gmbh System for the extrapolation of glucose concentration
BR0015716A (pt) 1999-11-19 2003-05-06 Spectrx Inc Dispositivo de interface de tecido org nico
US6575895B1 (en) 1999-11-26 2003-06-10 Bruce Blair Apparatus for facilitating analysis of dream activity
GB9927842D0 (en) 1999-11-26 2000-01-26 Koninkl Philips Electronics Nv Improved fabric antenna
US6658396B1 (en) 1999-11-29 2003-12-02 Tang Sharon S Neural network drug dosage estimation
US6522927B1 (en) 1999-12-01 2003-02-18 Vertis Neuroscience, Inc. Electrode assembly for a percutaneous electrical therapy system
US6377829B1 (en) 1999-12-09 2002-04-23 Masimo Corporation Resposable pulse oximetry sensor
WO2001041643A1 (en) 1999-12-13 2001-06-14 Arkray, Inc. Body fluid measuring apparatus with lancet and lancet holder used for the measuring apparatus
US6264810B1 (en) 1999-12-14 2001-07-24 Alcoa Inc. Electromechanical attachment of inert electrode to a current conductor
US6418346B1 (en) 1999-12-14 2002-07-09 Medtronic, Inc. Apparatus and method for remote therapy and diagnosis in medical devices via interface systems
US7060031B2 (en) 1999-12-17 2006-06-13 Medtronic, Inc. Method and apparatus for remotely programming implantable medical devices
US6497655B1 (en) 1999-12-17 2002-12-24 Medtronic, Inc. Virtual remote monitor, alert, diagnostics and programming for implantable medical device systems
US6602191B2 (en) 1999-12-17 2003-08-05 Q-Tec Systems Llp Method and apparatus for health and disease management combining patient data monitoring with wireless internet connectivity
US20020091796A1 (en) 2000-01-03 2002-07-11 John Higginson Method and apparatus for transmitting data over a network using a docking device
US7286894B1 (en) 2000-01-07 2007-10-23 Pasco Scientific Hand-held computer device and method for interactive data acquisition, analysis, annotation, and calibration
US7369635B2 (en) 2000-01-21 2008-05-06 Medtronic Minimed, Inc. Rapid discrimination preambles and methods for using the same
CA2396613C (en) 2000-01-21 2008-03-18 Medical Research Group, Inc. Microprocessor controlled ambulatory medical apparatus with hand held communication device
WO2001052935A1 (en) 2000-01-21 2001-07-26 Medical Research Group, Inc. Ambulatory medical apparatus and method having telemetry modifiable control software
US6810290B2 (en) 2000-01-21 2004-10-26 Medtronic Minimed, Inc. Ambulatory medical apparatus with hand held communication device
US6748445B1 (en) 2000-02-01 2004-06-08 Microsoft Corporation System and method for exchanging data
US20010037060A1 (en) 2000-02-08 2001-11-01 Thompson Richard P. Web site for glucose monitoring
US6484045B1 (en) 2000-02-10 2002-11-19 Medtronic Minimed, Inc. Analyte sensor and method of making the same
CA2395868C (en) 2000-02-10 2009-07-14 Medtronic Minimed, Inc. Improved analyte sensor and method of making the same
US7003336B2 (en) 2000-02-10 2006-02-21 Medtronic Minimed, Inc. Analyte sensor method of making the same
US20030060765A1 (en) 2000-02-16 2003-03-27 Arthur Campbell Infusion device menu structure and method of using the same
US7890295B2 (en) 2000-02-23 2011-02-15 Medtronic Minimed, Inc. Real time self-adjusting calibration algorithm
US6895263B2 (en) 2000-02-23 2005-05-17 Medtronic Minimed, Inc. Real time self-adjusting calibration algorithm
US7027931B1 (en) 2000-02-24 2006-04-11 Bionostics, Inc. System for statistical analysis of quality control data
US6893396B2 (en) 2000-03-01 2005-05-17 I-Medik, Inc. Wireless internet bio-telemetry monitoring system and interface
US6706159B2 (en) 2000-03-02 2004-03-16 Diabetes Diagnostics Combined lancet and electrochemical analyte-testing apparatus
DE10010587A1 (de) 2000-03-03 2001-09-06 Roche Diagnostics Gmbh System zur Bestimmung von Analytkonzentrationen in Körperflüssigkeiten
US6572542B1 (en) 2000-03-03 2003-06-03 Medtronic, Inc. System and method for monitoring and controlling the glycemic state of a patient
US6551496B1 (en) 2000-03-03 2003-04-22 Ysi Incorporated Microstructured bilateral sensor
US6435017B1 (en) 2000-03-16 2002-08-20 Motorola, Inc. Snap-fit sensing apparatus
US6405066B1 (en) 2000-03-17 2002-06-11 The Regents Of The University Of California Implantable analyte sensor
US6510344B1 (en) 2000-03-22 2003-01-21 Ge Medical Systems Information Technologies, Inc. Procedure alarm silence feature for medical telemetry system
CN100448392C (zh) 2000-03-29 2009-01-07 弗吉尼亚大学专利基金会 用于从自监控数据估计糖尿病中血糖控制的方法,系统,和计算机程序产品
WO2001075775A2 (en) 2000-04-04 2001-10-11 Contact Technology Systems, Inc. Arc fault current interrupter testing device
PL191428B1 (pl) 2000-04-06 2006-05-31 Htl Strefa Sp Z Oo Zespół regulacji głębokości nakłucia w przyrządzie do nakłuwania
US6610012B2 (en) 2000-04-10 2003-08-26 Healthetech, Inc. System and method for remote pregnancy monitoring
WO2001078577A2 (en) 2000-04-17 2001-10-25 Vivometrics, Inc. Systems and methods for ambulatory monitoring of physiological signs
US6671534B2 (en) 2000-04-19 2003-12-30 Ad-Tech Medical Instrument Corporation Electrical connector for multi-contact medical electrodes
US6561975B1 (en) 2000-04-19 2003-05-13 Medtronic, Inc. Method and apparatus for communicating with medical device systems
US20010034479A1 (en) 2000-04-19 2001-10-25 Ring Lawrence S. Optically based transcutaneous blood gas sensor
US6440068B1 (en) 2000-04-28 2002-08-27 International Business Machines Corporation Measuring user health as measured by multiple diverse health measurement devices utilizing a personal storage device
US7404815B2 (en) 2000-05-01 2008-07-29 Lifescan, Inc. Tissue ablation by shear force for sampling biological fluids and delivering active agents
US20020010390A1 (en) 2000-05-10 2002-01-24 Guice David Lehmann Method and system for monitoring the health and status of livestock and other animals
USD457247S1 (en) * 2000-05-12 2002-05-14 Gen-Probe Incorporated Cap
WO2001088524A1 (en) 2000-05-12 2001-11-22 Therasense, Inc. Electrodes with multilayer membranes and methods of using and making the electrodes
US7181261B2 (en) 2000-05-15 2007-02-20 Silver James H Implantable, retrievable, thrombus minimizing sensors
US7769420B2 (en) 2000-05-15 2010-08-03 Silver James H Sensors for detecting substances indicative of stroke, ischemia, or myocardial infarction
US6442413B1 (en) 2000-05-15 2002-08-27 James H. Silver Implantable sensor
US6459917B1 (en) 2000-05-22 2002-10-01 Ashok Gowda Apparatus for access to interstitial fluid, blood, or blood plasma components
US7395158B2 (en) 2000-05-30 2008-07-01 Sensys Medical, Inc. Method of screening for disorders of glucose metabolism
AU2001265128A1 (en) 2000-05-30 2001-12-11 Massachusetts Institute Of Technology Methods and devices for sealing microchip reservoir devices
US6537242B1 (en) 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US6607543B2 (en) * 2000-06-13 2003-08-19 Bayer Corporation Lancing mechanism
US6735479B2 (en) 2000-06-14 2004-05-11 Medtronic, Inc. Lifestyle management system
CA2689656A1 (en) 2000-06-16 2001-12-16 Bayer Healthcare Llc System, method and biosensor apparatus for data communications with a personal data assistant
US7261690B2 (en) 2000-06-16 2007-08-28 Bodymedia, Inc. Apparatus for monitoring health, wellness and fitness
DE10030410C1 (de) 2000-06-21 2002-01-24 Roche Diagnostics Gmbh Blutlanzettenvorrichtung zur Entnahme von Blut für Diagnosezwecke
US6494830B1 (en) 2000-06-22 2002-12-17 Guidance Interactive Technologies, Inc. Handheld controller for monitoring/using medical parameters
US6699188B2 (en) 2000-06-22 2004-03-02 Guidance Interactive Technologies Interactive reward devices and methods
BR0111918B1 (pt) 2000-06-23 2010-11-30 Bodymedia, Inc. aparelho para monitorar e reportar informação fisiológica humana.
US6540675B2 (en) 2000-06-27 2003-04-01 Rosedale Medical, Inc. Analyte monitor
US6400974B1 (en) 2000-06-29 2002-06-04 Sensors For Medicine And Science, Inc. Implanted sensor processing system and method for processing implanted sensor output
US7530964B2 (en) 2000-06-30 2009-05-12 Elan Pharma International Limited Needle device and method thereof
US6589229B1 (en) 2000-07-31 2003-07-08 Becton, Dickinson And Company Wearable, self-contained drug infusion device
WO2002017210A2 (en) 2000-08-18 2002-02-28 Cygnus, Inc. Formulation and manipulation of databases of analyte and associated values
US6553244B2 (en) 2000-08-18 2003-04-22 Cygnus, Inc. Analyte monitoring device alarm augmentation system
WO2002015777A1 (en) 2000-08-18 2002-02-28 Cygnus, Inc. Methods and devices for prediction of hypoglycemic events
US7297128B2 (en) 2000-08-21 2007-11-20 Gelzone, Inc. Arm suspension sleeve
AU2001288292A1 (en) 2000-08-21 2002-03-04 Euroceltique S.A. Near infrared blood glucose monitoring system
US20020026111A1 (en) 2000-08-28 2002-02-28 Neil Ackerman Methods of monitoring glucose levels in a subject and uses thereof
US6827899B2 (en) 2000-08-30 2004-12-07 Hypoguard Limited Test device
EP1335764B1 (en) 2000-09-08 2007-06-06 Insulet Corporation Device and system for patient infusion
US20020124017A1 (en) 2000-09-22 2002-09-05 Mault James R. Personal digital assistant with food scale accessory
EP1339312B1 (en) 2000-10-10 2006-01-04 Microchips, Inc. Microchip reservoir devices using wireless transmission of power and data
AU2001296403A1 (en) 2000-10-11 2002-04-22 Alfred E. Mann Foundation For Scientific Research Improved antenna for miniature implanted medical device
US6712025B2 (en) 2000-10-13 2004-03-30 Dogwatch, Inc. Receiver/stimulus unit for an animal control system
US7198603B2 (en) 2003-04-14 2007-04-03 Remon Medical Technologies, Inc. Apparatus and methods using acoustic telemetry for intrabody communications
US7348183B2 (en) 2000-10-16 2008-03-25 Board Of Trustees Of The University Of Arkansas Self-contained microelectrochemical bioassay platforms and methods
US6603995B1 (en) 2000-10-19 2003-08-05 Reynolds Medical Limited Body monitoring apparatus
US20020111832A1 (en) 2000-10-23 2002-08-15 Robert Judge Method and apparatus for delivering a pharmaceutical prescription copay counselor over an internet protocol network
CA2426330A1 (en) 2000-11-01 2002-05-10 3M Innovative Properties Company Electrical sensing and/or signal application device
US6695860B1 (en) 2000-11-13 2004-02-24 Isense Corp. Transcutaneous sensor insertion device
JP2004514981A (ja) 2000-11-22 2004-05-20 リケア・インコーポレイテッド 医学検査の医療上の発見を記録するシステム及び方法
US6574510B2 (en) 2000-11-30 2003-06-03 Cardiac Pacemakers, Inc. Telemetry apparatus and method for an implantable medical device
EP2578252B1 (en) 2000-11-30 2019-01-09 Valeritas, Inc. Device with substantially freely movable micro-probe over the housing
US6439446B1 (en) 2000-12-01 2002-08-27 Stephen J. Perry Safety lockout for actuator shaft
JP4348082B2 (ja) 2000-12-11 2009-10-21 レスメド・リミテッド 脳卒中発症後の患者の状況を判断するための装置
US20020072720A1 (en) 2000-12-11 2002-06-13 Hague Clifford W. Rigid soluble materials for use with needle-less infusion sets, sensor sets and injection devices and methods of making the same
TW492117B (en) 2000-12-15 2002-06-21 Acer Labs Inc Substrate layout method and structure thereof for decreasing crosstalk between adjacent signals
US6665558B2 (en) 2000-12-15 2003-12-16 Cardiac Pacemakers, Inc. System and method for correlation of patient health information and implant device data
US20020074162A1 (en) 2000-12-15 2002-06-20 Bor-Ray Su Substrate layout method and structure for reducing cross talk of adjacent signals
GB0030929D0 (en) * 2000-12-19 2001-01-31 Inverness Medical Ltd Analyte measurement
US7052483B2 (en) 2000-12-19 2006-05-30 Animas Corporation Transcutaneous inserter for low-profile infusion sets
US6416332B1 (en) 2000-12-20 2002-07-09 Nortel Networks Limited Direct BGA socket for high speed use
US20020147135A1 (en) 2000-12-21 2002-10-10 Oliver Schnell Method and device for producing an adapted travel treatment plan for administering a medicine in the event of a long-haul journey
ATE412366T1 (de) 2000-12-29 2008-11-15 Ares Medical Inc Risikobewertung von schlafapnoe
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
WO2002062215A2 (en) 2001-01-04 2002-08-15 Medtronic, Inc. Implantable medical device with sensor
US6666821B2 (en) 2001-01-08 2003-12-23 Medtronic, Inc. Sensor system
JP4178201B2 (ja) * 2001-01-12 2008-11-12 アークレイ株式会社 穿刺装置
US6970529B2 (en) 2001-01-16 2005-11-29 International Business Machines Corporation Unified digital architecture
US6603770B2 (en) 2001-01-16 2003-08-05 Physical Optics Corporation Apparatus and method for accessing a network
US6529752B2 (en) 2001-01-17 2003-03-04 David T. Krausman Sleep disorder breathing event counter
US20040197846A1 (en) 2001-01-18 2004-10-07 Linda Hockersmith Determination of glucose sensitivity and a method to manipulate blood glucose concentration
TW536689B (en) 2001-01-18 2003-06-11 Sharp Kk Display, portable device, and substrate
US7691071B2 (en) 2001-01-19 2010-04-06 Panasonic Corporation Lancet-integrated sensor, measurer for lancet-integrated sensor, and cartridge
BR0206604A (pt) 2001-01-22 2004-02-17 Hoffmann La Roche Dispositivo de lanceta que tem ação capilar
WO2002056940A2 (en) 2001-01-22 2002-07-25 Integrated Sensing Systems, Inc. Sensing catheter system and method of fabrication
ITMI20010253A1 (it) 2001-02-08 2002-08-08 Negri Bossi Spa Gruppo di iniezione per presse ad iniezione di materiali plastici
US7014610B2 (en) 2001-02-09 2006-03-21 Medtronic, Inc. Echogenic devices and methods of making and using such devices
WO2002068015A2 (en) 2001-02-22 2002-09-06 Insulet Corporation Modular infusion device and method
US6525330B2 (en) 2001-02-28 2003-02-25 Home Diagnostics, Inc. Method of strip insertion detection
EP1384193A2 (en) 2001-03-14 2004-01-28 Baxter International Inc. Internet based therapy management system
AU2002247321A1 (en) 2001-03-14 2002-09-24 Vitaltrak Technology, Inc. Tracking device
US6611206B2 (en) 2001-03-15 2003-08-26 Koninklijke Philips Electronics N.V. Automatic system for monitoring independent person requiring occasional assistance
US6968294B2 (en) 2001-03-15 2005-11-22 Koninklijke Philips Electronics N.V. Automatic system for monitoring person requiring care and his/her caretaker
US7041468B2 (en) 2001-04-02 2006-05-09 Therasense, Inc. Blood glucose tracking apparatus and methods
EP3210637B1 (de) 2001-04-06 2021-01-27 F. Hoffmann-La Roche AG Infusionsset
DE10117285B4 (de) 2001-04-06 2016-08-04 Roche Diabetes Care Gmbh Kanülensystem
US6574490B2 (en) 2001-04-11 2003-06-03 Rio Grande Medical Technologies, Inc. System for non-invasive measurement of glucose in humans
US7916013B2 (en) 2005-03-21 2011-03-29 Greatbatch Ltd. RFID detection and identification system for implantable medical devices
GR1003802B (el) 2001-04-17 2002-02-08 Micrel �.�.�. ������� ��������� ��������������� ��������� Συστημα τηλειατρικης.
SE0101379D0 (sv) † 2001-04-18 2001-04-18 Diabact Ab Komposition som hämmar utsöndring av magsyra
US6698269B2 (en) 2001-04-27 2004-03-02 Oceana Sensor Technologies, Inc. Transducer in-situ testing apparatus and method
US20020161338A1 (en) 2001-04-30 2002-10-31 Francis Peterson Catheters and catheter safety guards
US6535764B2 (en) 2001-05-01 2003-03-18 Intrapace, Inc. Gastric treatment and diagnosis device and method
WO2002089664A2 (en) 2001-05-03 2002-11-14 Masimo Corporation Flex circuit shielded optical sensor and method of fabricating the same
US20020164836A1 (en) 2001-05-07 2002-11-07 Advanced Semiconductor Engineering Inc. Method of manufacturing printed circuit board
US6613379B2 (en) 2001-05-08 2003-09-02 Isense Corp. Implantable analyte sensor
US6676816B2 (en) 2001-05-11 2004-01-13 Therasense, Inc. Transition metal complexes with (pyridyl)imidazole ligands and sensors using said complexes
US7395214B2 (en) 2001-05-11 2008-07-01 Craig P Shillingburg Apparatus, device and method for prescribing, administering and monitoring a treatment regimen for a patient
US7314453B2 (en) 2001-05-14 2008-01-01 Youti Kuo Handheld diagnostic device with renewable biosensor
US6932894B2 (en) 2001-05-15 2005-08-23 Therasense, Inc. Biosensor membranes composed of polymers containing heterocyclic nitrogens
US6549796B2 (en) 2001-05-25 2003-04-15 Lifescan, Inc. Monitoring analyte concentration using minimally invasive devices
WO2002099916A2 (en) 2001-06-01 2002-12-12 Polyfuel, Inc Fuel cell assembly for portable electronic device and interface, control, and regulator circuit for fuel cell powered electronic device
US6837988B2 (en) 2001-06-12 2005-01-04 Lifescan, Inc. Biological fluid sampling and analyte measurement devices and methods
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
US7179226B2 (en) 2001-06-21 2007-02-20 Animas Corporation System and method for managing diabetes
WO2003000127A2 (en) 2001-06-22 2003-01-03 Cygnus, Inc. Method for improving the performance of an analyte monitoring system
WO2003000125A1 (en) 2001-06-22 2003-01-03 Cardiodigital Limited Wavelet-based analysis of pulse oximetry signals
WO2003000141A1 (en) 2001-06-25 2003-01-03 Abbott Laboratories Apparatus and methods for performing an anastomosis
US7044911B2 (en) 2001-06-29 2006-05-16 Philometron, Inc. Gateway platform for biological monitoring and delivery of therapeutic compounds
US20030002682A1 (en) 2001-07-02 2003-01-02 Phonex Broadband Corporation Wireless audio/mechanical vibration transducer and audio/visual transducer
ATE483400T1 (de) 2001-07-11 2010-10-15 Arkray Inc Lanzette
US20030208113A1 (en) 2001-07-18 2003-11-06 Mault James R Closed loop glycemic index system
US6754516B2 (en) 2001-07-19 2004-06-22 Nellcor Puritan Bennett Incorporated Nuisance alarm reductions in a physiological monitor
US20030032874A1 (en) 2001-07-27 2003-02-13 Dexcom, Inc. Sensor head for use with implantable devices
US6702857B2 (en) 2001-07-27 2004-03-09 Dexcom, Inc. Membrane for use with implantable devices
US6570386B2 (en) 2001-07-30 2003-05-27 Hewlett-Packard Development Company, L.P. System and method for providing power to electrical devices
US6544212B2 (en) 2001-07-31 2003-04-08 Roche Diagnostics Corporation Diabetes management system
US6788965B2 (en) 2001-08-03 2004-09-07 Sensys Medical, Inc. Intelligent system for detecting errors and determining failure modes in noninvasive measurement of blood and tissue analytes
JP3775263B2 (ja) 2001-08-10 2006-05-17 ニプロ株式会社 記録媒体およびこの記録媒体を用いた血糖測定システム
US20040142403A1 (en) 2001-08-13 2004-07-22 Donald Hetzel Method of screening for disorders of glucose metabolism
US6827718B2 (en) 2001-08-14 2004-12-07 Scimed Life Systems, Inc. Method of and apparatus for positioning and maintaining the position of endoscopic instruments
JP2004538078A (ja) 2001-08-20 2004-12-24 インバネス・メディカル・リミテッド 無線糖尿病管理装置および無線糖尿病管理装置の使用方法
US7736272B2 (en) 2001-08-21 2010-06-15 Pantometrics, Ltd. Exercise system with graphical feedback and method of gauging fitness progress
ATE487130T1 (de) 2001-08-22 2010-11-15 Instrumentation Lab Co Verfahren und vorrichtung zur kalibrierung von sensoren
US6781522B2 (en) 2001-08-22 2004-08-24 Kivalo, Inc. Portable storage case for housing a medical monitoring device and an associated method for communicating therewith
US6814844B2 (en) 2001-08-29 2004-11-09 Roche Diagnostics Corporation Biosensor with code pattern
JP3962250B2 (ja) 2001-08-29 2007-08-22 株式会社レアメタル 生体内情報検出システム及びこれに用いるタグ装置、中継装置
US7025760B2 (en) 2001-09-07 2006-04-11 Medtronic Minimed, Inc. Method and system for non-vascular sensor implantation
US6740072B2 (en) 2001-09-07 2004-05-25 Medtronic Minimed, Inc. System and method for providing closed loop infusion formulation delivery
US6827702B2 (en) 2001-09-07 2004-12-07 Medtronic Minimed, Inc. Safety limits for closed-loop infusion pump control
WO2003022142A2 (en) 2001-09-13 2003-03-20 The Boeing Company Method for transmitting vital health statistics to a remote location form an aircraft
JP2003084101A (ja) 2001-09-17 2003-03-19 Dainippon Printing Co Ltd 光学素子用樹脂組成物、光学素子、およびプロジェクションスクリーン
US20030055380A1 (en) 2001-09-19 2003-03-20 Flaherty J. Christopher Plunger for patient infusion device
US7052591B2 (en) 2001-09-21 2006-05-30 Therasense, Inc. Electrodeposition of redox polymers and co-electrodeposition of enzymes by coordinative crosslinking
CN1202872C (zh) * 2001-09-24 2005-05-25 崔秀峯 具有血糖测定功能的便携式自动胰岛素注射装置
US6830562B2 (en) 2001-09-27 2004-12-14 Unomedical A/S Injector device for placing a subcutaneous infusion set
US20050137480A1 (en) 2001-10-01 2005-06-23 Eckhard Alt Remote control of implantable device through medical implant communication service band
US20030069510A1 (en) 2001-10-04 2003-04-10 Semler Herbert J. Disposable vital signs monitor
US6613015B2 (en) 2001-10-04 2003-09-02 Deltec, Inc. Right angle safety needle
US6939310B2 (en) 2001-10-10 2005-09-06 Lifescan, Inc. Devices for physiological fluid sampling and methods of using the same
US6748254B2 (en) 2001-10-12 2004-06-08 Nellcor Puritan Bennett Incorporated Stacked adhesive optical sensor
US7010356B2 (en) * 2001-10-31 2006-03-07 London Health Sciences Centre Research Inc. Multichannel electrode and methods of using same
US6971999B2 (en) 2001-11-14 2005-12-06 Medical Instill Technologies, Inc. Intradermal delivery device and method
US20060006141A1 (en) 2001-11-16 2006-01-12 Stefan Ufer Biomedical electrochemical sensor array and method of fabrication
US20030116447A1 (en) 2001-11-16 2003-06-26 Surridge Nigel A. Electrodes, methods, apparatuses comprising micro-electrode arrays
EP1461745A4 (en) 2001-11-28 2006-10-18 Phemi Inc METHODS AND APPARATUS FOR AUTOMATED INTERACTIVE AMBULATORY MEDICAL MANAGEMENT
WO2003049424A1 (fr) 2001-12-03 2003-06-12 Nikon Corporation Appareil electronique, camera electronique, dispositif electronique, appareil d'affichage d'image et systeme de transmission d'image
US7729776B2 (en) 2001-12-19 2010-06-01 Cardiac Pacemakers, Inc. Implantable medical device with two or more telemetry systems
US20030119457A1 (en) 2001-12-19 2003-06-26 Standke Randolph E. Filter technique for increasing antenna isolation in portable communication devices
US6993393B2 (en) 2001-12-19 2006-01-31 Cardiac Pacemakers, Inc. Telemetry duty cycle management system for an implantable medical device
US7204823B2 (en) 2001-12-19 2007-04-17 Medtronic Minimed, Inc. Medication delivery system and monitor
US7082334B2 (en) 2001-12-19 2006-07-25 Medtronic, Inc. System and method for transmission of medical and like data from a patient to a dedicated internet website
GB0130684D0 (en) 2001-12-21 2002-02-06 Oxford Biosensors Ltd Micro-band electrode
US7022072B2 (en) 2001-12-27 2006-04-04 Medtronic Minimed, Inc. System for monitoring physiological characteristics
US7399277B2 (en) 2001-12-27 2008-07-15 Medtronic Minimed, Inc. System for monitoring physiological characteristics
US20080255438A1 (en) 2001-12-27 2008-10-16 Medtronic Minimed, Inc. System for monitoring physiological characteristics
US20050027182A1 (en) 2001-12-27 2005-02-03 Uzair Siddiqui System for monitoring physiological characteristics
ITTO20011228A1 (it) * 2001-12-28 2003-06-28 Cane Srl Contenitore per ago monouso.
US20030145062A1 (en) 2002-01-14 2003-07-31 Dipanshu Sharma Data conversion server for voice browsing system
US20030155656A1 (en) 2002-01-18 2003-08-21 Chiu Cindy Chia-Wen Anisotropically conductive film
US7169107B2 (en) 2002-01-25 2007-01-30 Karen Jersey-Willuhn Conductivity reconstruction based on inverse finite element measurements in a tissue monitoring system
US20030144711A1 (en) 2002-01-29 2003-07-31 Neuropace, Inc. Systems and methods for interacting with an implantable medical device
US6985773B2 (en) 2002-02-07 2006-01-10 Cardiac Pacemakers, Inc. Methods and apparatuses for implantable medical device telemetry power management
US7004928B2 (en) 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
US8260393B2 (en) 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US9247901B2 (en) 2003-08-22 2016-02-02 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8364229B2 (en) 2003-07-25 2013-01-29 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US9282925B2 (en) 2002-02-12 2016-03-15 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US7613491B2 (en) 2002-05-22 2009-11-03 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
DE20213607U1 (de) 2002-02-21 2003-07-03 Paul Hartmann AG, 89522 Heidenheim Blutanalysegerät zur Bestimmung eines Analyten
US20030212379A1 (en) 2002-02-26 2003-11-13 Bylund Adam David Systems and methods for remotely controlling medication infusion and analyte monitoring
US7056302B2 (en) 2002-02-26 2006-06-06 Sterling Medivations, Inc. Insertion device for an insertion set and method of using the same
WO2003073936A2 (en) 2002-03-06 2003-09-12 'htl Strefa' Sp. Z O.O. A device for puncturing patient's skin
US7043305B2 (en) 2002-03-06 2006-05-09 Cardiac Pacemakers, Inc. Method and apparatus for establishing context among events and optimizing implanted medical device performance
US7468032B2 (en) 2002-12-18 2008-12-23 Cardiac Pacemakers, Inc. Advanced patient management for identifying, displaying and assisting with correlating health-related data
US6998247B2 (en) 2002-03-08 2006-02-14 Sensys Medical, Inc. Method and apparatus using alternative site glucose determinations to calibrate and maintain noninvasive and implantable analyzers
EP1343112A1 (en) 2002-03-08 2003-09-10 EndoArt S.A. Implantable device
US6936006B2 (en) 2002-03-22 2005-08-30 Novo Nordisk, A/S Atraumatic insertion of a subcutaneous device
US20040030531A1 (en) 2002-03-28 2004-02-12 Honeywell International Inc. System and method for automated monitoring, recognizing, supporting, and responding to the behavior of an actor
GB2388898B (en) 2002-04-02 2005-10-05 Inverness Medical Ltd Integrated sample testing meter
US7027848B2 (en) 2002-04-04 2006-04-11 Inlight Solutions, Inc. Apparatus and method for non-invasive spectroscopic measurement of analytes in tissue using a matched reference analyte
AU2003223652A1 (en) 2002-04-16 2003-11-03 Carematix, Inc. Method and apparatus for remotely monitoring the condition of a patient
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7485128B2 (en) 2002-04-19 2009-02-03 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7141058B2 (en) 2002-04-19 2006-11-28 Pelikan Technologies, Inc. Method and apparatus for a body fluid sampling device using illumination
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US7410468B2 (en) 2002-04-19 2008-08-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US6960192B1 (en) 2002-04-23 2005-11-01 Insulet Corporation Transcutaneous fluid delivery system
US6743635B2 (en) 2002-04-25 2004-06-01 Home Diagnostics, Inc. System and methods for blood glucose sensing
US20050177398A1 (en) 2002-04-25 2005-08-11 Motokazu Watanabe Dosage determination supporting device, injector, and health management supporting system
US6810309B2 (en) 2002-04-25 2004-10-26 Visteon Global Technologies, Inc. Vehicle personalization via biometric identification
US6983867B1 (en) 2002-04-29 2006-01-10 Dl Technology Llc Fluid dispense pump with drip prevention mechanism and method for controlling same
US6758835B2 (en) 2002-05-01 2004-07-06 Medtg, Llc Disposable needle assembly having sensors formed therein permitting the simultaneous drawing and administering of fluids and method of forming the same
GB2388715B (en) 2002-05-13 2005-08-03 Splashpower Ltd Improvements relating to the transfer of electromagnetic power
US7015817B2 (en) 2002-05-14 2006-03-21 Shuan Michael Copley Personal tracking device
US7134994B2 (en) 2002-05-20 2006-11-14 Volcano Corporation Multipurpose host system for invasive cardiovascular diagnostic measurement acquisition and display
US7226978B2 (en) 2002-05-22 2007-06-05 Dexcom, Inc. Techniques to improve polyurethane membranes for implantable glucose sensors
US7854890B2 (en) 2002-05-23 2010-12-21 Arkray, Inc. Analytical tool, analytical tool pack, cartridge including plurality of packs, method of making analytical tool pack, analyzer, and mechanism for taking out object
DE10223558A1 (de) 2002-05-28 2003-12-11 Roche Diagnostics Gmbh Blutentnahmesystem
US8641715B2 (en) 2002-05-31 2014-02-04 Vidacare Corporation Manual intraosseous device
US20040030581A1 (en) 2002-06-12 2004-02-12 Samuel Leven Heart monitoring device
US20030236489A1 (en) 2002-06-21 2003-12-25 Baxter International, Inc. Method and apparatus for closed-loop flow control system
EP1541087B1 (en) 2002-07-01 2013-02-27 Terumo Kabushiki Kaisha Body fluid sampling device
JP4308483B2 (ja) 2002-07-02 2009-08-05 アークレイ株式会社 穿刺用ユニットおよび穿刺装置
EP1671584B1 (en) 2002-07-02 2015-10-14 ARKRAY, Inc. Lancing unit and lancing apparatus
US7124027B1 (en) 2002-07-11 2006-10-17 Yazaki North America, Inc. Vehicular collision avoidance system
US20040010207A1 (en) 2002-07-15 2004-01-15 Flaherty J. Christopher Self-contained, automatic transcutaneous physiologic sensing system
US7018360B2 (en) 2002-07-16 2006-03-28 Insulet Corporation Flow restriction system and method for patient infusion device
JP2004054394A (ja) 2002-07-17 2004-02-19 Toshiba Corp 無線情報処理システム、無線情報記録媒体、無線情報処理装置、及び無線情報処理システムの通信方法
AU2003302720B9 (en) 2002-07-19 2008-08-21 Smiths Detection-Pasadena, Inc. Non-specific sensor array detectors
US7470533B2 (en) 2002-12-20 2008-12-30 Acea Biosciences Impedance based devices and methods for use in assays
US7058719B2 (en) 2002-07-22 2006-06-06 Ricoh Company, Ltd. System, computer program product and method for managing and controlling a local network of electronic devices and reliably and securely adding an electronic device to the network
US7220387B2 (en) 2002-07-23 2007-05-22 Apieron Biosystems Corp. Disposable sensor for use in measuring an analyte in a gaseous sample
US7278983B2 (en) 2002-07-24 2007-10-09 Medtronic Minimed, Inc. Physiological monitoring device for controlling a medication infusion device
US8512276B2 (en) 2002-07-24 2013-08-20 Medtronic Minimed, Inc. System for providing blood glucose measurements to an infusion device
US6992580B2 (en) 2002-07-25 2006-01-31 Motorola, Inc. Portable communication device and corresponding method of operation
EP2327359B1 (en) 2002-08-13 2015-01-21 University Of Virginia Patent Foundation Method, system, and computer program product for processing of self-monitoring blood glucose (smbg) data to enhance diabetic self-management
US7020508B2 (en) 2002-08-22 2006-03-28 Bodymedia, Inc. Apparatus for detecting human physiological and contextual information
US7404796B2 (en) 2004-03-01 2008-07-29 Becton Dickinson And Company System for determining insulin dose using carbohydrate to insulin ratio and insulin sensitivity factor
CN1723053A (zh) 2002-09-12 2006-01-18 儿童医院医疗中心 无痛药物注射的方法和设备
US20040061232A1 (en) 2002-09-27 2004-04-01 Medtronic Minimed, Inc. Multilayer substrate
US7736309B2 (en) 2002-09-27 2010-06-15 Medtronic Minimed, Inc. Implantable sensor method and system
US7144384B2 (en) 2002-09-30 2006-12-05 Insulet Corporation Dispenser components and methods for patient infusion device
US7192405B2 (en) 2002-09-30 2007-03-20 Becton, Dickinson And Company Integrated lancet and bodily fluid sensor
TW557352B (en) 2002-10-07 2003-10-11 Actherm Inc Electronic clinical thermometer with rapid response
US7014625B2 (en) 2002-10-07 2006-03-21 Novo Nordick A/S Needle insertion device
EP1556103A1 (en) 2002-10-07 2005-07-27 Novo Nordisk A/S Needle device comprising a plurality of needles
JP2006517804A (ja) 2002-10-09 2006-08-03 シーエスピー テクノロジーズ，インコーポレイティド テスト用ストリップと体内物質を採取かつサンプリングするためのカセットとを有するランセット・システム
US20090177068A1 (en) 2002-10-09 2009-07-09 Stivoric John M Method and apparatus for providing derived glucose information utilizing physiological and/or contextual parameters
WO2005061041A1 (en) 2002-10-11 2005-07-07 Becton, Dickinson And Company Insulin delivery system with sensor
AU2003287159A1 (en) 2002-10-15 2004-05-04 Medtronic Inc. Synchronization and calibration of clocks for a medical device and calibrated clock
US20040073266A1 (en) 2002-10-15 2004-04-15 Haefner Paul A. Automatic detection of defibrillation lead
US7381184B2 (en) 2002-11-05 2008-06-03 Abbott Diabetes Care Inc. Sensor inserter assembly
US7572237B2 (en) 2002-11-06 2009-08-11 Abbott Diabetes Care Inc. Automatic biological analyte testing meter with integrated lancing device and methods of use
GB0226648D0 (en) 2002-11-15 2002-12-24 Koninkl Philips Electronics Nv Usage data harvesting
US6676290B1 (en) 2002-11-15 2004-01-13 Hsueh-Yu Lu Electronic clinical thermometer
EP1579181B1 (en) 2002-11-21 2007-01-17 S. C. Johnson & Son, Inc. Products having rfid tags for wireless interrogation
US20040100376A1 (en) 2002-11-26 2004-05-27 Kimberly-Clark Worldwide, Inc. Healthcare monitoring system
US7580395B2 (en) 2002-11-29 2009-08-25 Intermec Ip Corp. Information gathering apparatus and method having multiple wireless communication options
EP1424637A1 (en) 2002-11-29 2004-06-02 Instrumentarium Corporation Artifact removal from an electric signal
AU2003289047A1 (en) 2002-12-13 2004-07-09 Arkray, Inc. Needle-insertion device
KR20050111308A (ko) 2002-12-16 2005-11-24 미간 메디칼, 인코퍼레이티드 경피적 적용 깊이의 제어
US20040116866A1 (en) 2002-12-17 2004-06-17 William Gorman Skin attachment apparatus and method for patient infusion device
US7009511B2 (en) 2002-12-17 2006-03-07 Cardiac Pacemakers, Inc. Repeater device for communications with an implantable medical device
US20040122353A1 (en) 2002-12-19 2004-06-24 Medtronic Minimed, Inc. Relay device for transferring information between a sensor system and a fluid delivery system
US20050038680A1 (en) 2002-12-19 2005-02-17 Mcmahon Kevin Lee System and method for glucose monitoring
US7395117B2 (en) 2002-12-23 2008-07-01 Cardiac Pacemakers, Inc. Implantable medical device having long-term wireless capabilities
US6756681B1 (en) 2002-12-23 2004-06-29 Nokia Corporation Radio frequency integrated circuit having increased substrate resistance enabling three dimensional interconnection with feedthroughs
US7833151B2 (en) 2002-12-26 2010-11-16 Given Imaging Ltd. In vivo imaging device with two imagers
JP2004214014A (ja) 2002-12-27 2004-07-29 Shin Etsu Polymer Co Ltd 電気コネクタ
US20040127818A1 (en) 2002-12-27 2004-07-01 Roe Steven N. Precision depth control lancing tip
AU2003303597A1 (en) 2002-12-31 2004-07-29 Therasense, Inc. Continuous glucose monitoring system and methods of use
US7154398B2 (en) 2003-01-06 2006-12-26 Chen Thomas C H Wireless communication and global location enabled intelligent health monitoring system
US7228162B2 (en) 2003-01-13 2007-06-05 Isense Corporation Analyte sensor
US7120483B2 (en) 2003-01-13 2006-10-10 Isense Corporation Methods for analyte sensing and measurement
US20040138544A1 (en) 2003-01-13 2004-07-15 Ward W. Kenneth Body fluid trap anlyte sensor
EP1584291A4 (en) 2003-01-17 2009-04-29 Panasonic Corp Apparatus for measuring biological component
US20040140211A1 (en) 2003-01-21 2004-07-22 Broy Stephen H. Modular interface and coupling system and method
US20040152366A1 (en) 2003-01-31 2004-08-05 Schultz David J. Rehabilitation kit for closures
CA2457987C (en) 2003-02-18 2013-07-09 Microteq Llc System, method, and apparatus for detecting breach of exposure protection equipment
GB0304424D0 (en) 2003-02-26 2003-04-02 Glaxosmithkline Biolog Sa Novel compounds
JP4675776B2 (ja) * 2003-02-26 2011-04-27 東京応化工業株式会社 ポジ型レジスト組成物、レジスト積層体及びレジストパターン形成方法
US20040171910A1 (en) 2003-02-27 2004-09-02 Moore-Steele Robin B. Sexually stimulating panty insert
US7413749B2 (en) 2003-03-11 2008-08-19 Purdue Pharma L.P. Titration dosing regimen for controlled release tramadol
DE602004023920D1 (de) 2003-03-17 2009-12-17 Arkray Inc Punktionsvorrichtung
WO2004084820A2 (en) 2003-03-19 2004-10-07 Harry Hebblewhite Method and system for determining insulin dosing schedules and carbohydrate-to-insulin ratios in diabetic patients
US20040186373A1 (en) 2003-03-21 2004-09-23 Dunfield John Stephen Method and device for targeted epithelial delivery of medicinal and related agents
US7473264B2 (en) 2003-03-28 2009-01-06 Lifescan, Inc. Integrated lance and strip for analyte measurement
US20050070819A1 (en) 2003-03-31 2005-03-31 Rosedale Medical, Inc. Body fluid sampling constructions and techniques
US7447298B2 (en) 2003-04-01 2008-11-04 Cabot Microelectronics Corporation Decontamination and sterilization system using large area x-ray source
US20040199056A1 (en) 2003-04-03 2004-10-07 International Business Machines Corporation Body monitoring using local area wireless interfaces
US7134999B2 (en) 2003-04-04 2006-11-14 Dexcom, Inc. Optimized sensor geometry for an implantable glucose sensor
US7587287B2 (en) 2003-04-04 2009-09-08 Abbott Diabetes Care Inc. Method and system for transferring analyte test data
US20040204868A1 (en) 2003-04-09 2004-10-14 Maynard John D. Reduction of errors in non-invasive tissue sampling
WO2004091401A1 (ja) 2003-04-11 2004-10-28 Arkray Inc. 穿刺装置
SG182002A1 (en) 2003-04-15 2012-07-30 Sensors For Med & Science Inc System and method for attenuating the effect of ambient light on an optical sensor
US6797877B1 (en) 2003-04-28 2004-09-28 Jonn Maneely Company Electrical metallic tube, coupling, and connector apparatus and method
US6805686B1 (en) 2003-05-06 2004-10-19 Abbott Laboratories Autoinjector with extendable needle protector shroud
US20040225199A1 (en) 2003-05-08 2004-11-11 Evanyk Shane Walter Advanced physiological monitoring systems and methods
DE602004013140T2 (de) 2003-05-08 2009-07-02 Novo Nordisk A/S Interne nadeleinführvorrichtung
EP1475113A1 (en) 2003-05-08 2004-11-10 Novo Nordisk A/S External needle inserter
DE602004028231D1 (de) 2003-05-08 2010-09-02 Novo Nordisk As Eine auf die haut aufbringbare injektionsvorrichtung mit abtrennbarem betätigungsteil zum einführen der nadel
DE602004025568D1 (de) 2003-05-08 2010-04-01 Novo Nordisk As Schwenkbare vorrichtung für eine injektionsnadel
AU2003902187A0 (en) 2003-05-08 2003-05-22 Aimedics Pty Ltd Patient monitor
US6926694B2 (en) * 2003-05-09 2005-08-09 Medsolve Technologies, Llc Apparatus and method for delivery of therapeutic and/or diagnostic agents
US7875293B2 (en) 2003-05-21 2011-01-25 Dexcom, Inc. Biointerface membranes incorporating bioactive agents
WO2004103170A1 (en) 2003-05-22 2004-12-02 Novo Nordisk A/S A glucose measuring device
US7397785B2 (en) 2003-05-28 2008-07-08 Nokia Corporation Method for enhancing fairness and performance in a multihop ad hoc network and corresponding system
KR100502713B1 (ko) 2003-05-29 2005-07-20 주식회사 헬스피아 자가 진단용 배터리 팩과 자가 진단 시스템
JP2004358016A (ja) 2003-06-06 2004-12-24 Nipro Corp 穿刺ルートに沿って刺入が容易な穿刺針
US7258673B2 (en) 2003-06-06 2007-08-21 Lifescan, Inc Devices, systems and methods for extracting bodily fluid and monitoring an analyte therein
US20060258939A1 (en) 2003-06-09 2006-11-16 Glucon, Inc. Wearable glucometer
US7040139B2 (en) 2003-06-10 2006-05-09 Smiths Detection Inc. Sensor arrangement
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
US8460243B2 (en) 2003-06-10 2013-06-11 Abbott Diabetes Care Inc. Glucose measuring module and insulin pump combination
WO2006001797A1 (en) * 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
ES2293273T3 (es) 2003-06-12 2008-03-16 Disetronic Licensing Ag Dispositivo de insercion para equipos de infusion.
US20040254433A1 (en) 2003-06-12 2004-12-16 Bandis Steven D. Sensor introducer system, apparatus and method
DE20320207U1 (de) * 2003-06-12 2004-10-14 Disetronic Licensing Ag Insertionsvorrichtung für Infusionssets
US7604592B2 (en) 2003-06-13 2009-10-20 Pelikan Technologies, Inc. Method and apparatus for a point of care device
US7364699B2 (en) 2003-06-18 2008-04-29 Bayer Healthcare Llc Containers for reading and handling diagnostic reagents and methods of using the same
US7155290B2 (en) 2003-06-23 2006-12-26 Cardiac Pacemakers, Inc. Secure long-range telemetry for implantable medical device
JP4041018B2 (ja) 2003-06-25 2008-01-30 Ｔｄｋ株式会社 温度センサ
US7510564B2 (en) 2003-06-27 2009-03-31 Abbott Diabetes Care Inc. Lancing device
US7242981B2 (en) 2003-06-30 2007-07-10 Codman Neuro Sciences Sárl System and method for controlling an implantable medical device subject to magnetic field or radio frequency exposure
US7722536B2 (en) 2003-07-15 2010-05-25 Abbott Diabetes Care Inc. Glucose measuring device integrated into a holster for a personal area network device
WO2005007223A2 (en) 2003-07-16 2005-01-27 Sasha John Programmable medical drug delivery systems and methods for delivery of multiple fluids and concentrations
WO2005010518A1 (en) 2003-07-23 2005-02-03 Dexcom, Inc. Rolled electrode array and its method for manufacture
WO2005010756A2 (en) 2003-07-25 2005-02-03 Philips Intellectual Property & Standards Gmbh Method and device for monitoring a system
US8423113B2 (en) 2003-07-25 2013-04-16 Dexcom, Inc. Systems and methods for processing sensor data
WO2005019795A2 (en) 2003-07-25 2005-03-03 Dexcom, Inc. Electrochemical sensors including electrode systems with increased oxygen generation
US20050176136A1 (en) 2003-11-19 2005-08-11 Dexcom, Inc. Afinity domain for analyte sensor
US7366556B2 (en) 2003-12-05 2008-04-29 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7651596B2 (en) 2005-04-08 2010-01-26 Dexcom, Inc. Cellulosic-based interference domain for an analyte sensor
US7467003B2 (en) 2003-12-05 2008-12-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7424318B2 (en) 2003-12-05 2008-09-09 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
JP2007500336A (ja) 2003-07-25 2007-01-11 デックスコム・インコーポレーテッド 電気化学センサーに用いる電極システム
US7460898B2 (en) 2003-12-05 2008-12-02 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
WO2005012871A2 (en) 2003-07-25 2005-02-10 Dexcom, Inc. Increasing bias for oxygen production in an electrode system
EP1648298A4 (en) 2003-07-25 2010-01-13 Dexcom Inc OXYGEN-IMPROVED MEMBRANE SYSTEMS FOR IMPLANTABLE DEVICES
US7761130B2 (en) 2003-07-25 2010-07-20 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US9135402B2 (en) 2007-12-17 2015-09-15 Dexcom, Inc. Systems and methods for processing sensor data
US20070208245A1 (en) 2003-08-01 2007-09-06 Brauker James H Transcutaneous analyte sensor
EP1502613A1 (en) 2003-08-01 2005-02-02 Novo Nordisk A/S Needle device with retraction means
US20080119703A1 (en) 2006-10-04 2008-05-22 Mark Brister Analyte sensor
US8275437B2 (en) 2003-08-01 2012-09-25 Dexcom, Inc. Transcutaneous analyte sensor
US8676287B2 (en) 2003-08-01 2014-03-18 Dexcom, Inc. System and methods for processing analyte sensor data
US7959569B2 (en) 2003-08-01 2011-06-14 Dexcom, Inc. System and methods for processing analyte sensor data
US7774145B2 (en) 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
US8160669B2 (en) 2003-08-01 2012-04-17 Dexcom, Inc. Transcutaneous analyte sensor
US8369919B2 (en) 2003-08-01 2013-02-05 Dexcom, Inc. Systems and methods for processing sensor data
US8886273B2 (en) 2003-08-01 2014-11-11 Dexcom, Inc. Analyte sensor
US8626257B2 (en) 2003-08-01 2014-01-07 Dexcom, Inc. Analyte sensor
US7276029B2 (en) 2003-08-01 2007-10-02 Dexcom, Inc. System and methods for processing analyte sensor data
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US8845536B2 (en) 2003-08-01 2014-09-30 Dexcom, Inc. Transcutaneous analyte sensor
DE10336933B4 (de) 2003-08-07 2007-04-26 Roche Diagnostics Gmbh Blutentnahmesystem
US20050038331A1 (en) 2003-08-14 2005-02-17 Grayson Silaski Insertable sensor assembly having a coupled inductor communicative system
US7905898B2 (en) 2003-08-15 2011-03-15 Stat Medical Devices, Inc. Adjustable lancet device and method
US6954662B2 (en) 2003-08-19 2005-10-11 A.D. Integrity Applications, Ltd. Method of monitoring glucose level
US8233959B2 (en) 2003-08-22 2012-07-31 Dexcom, Inc. Systems and methods for processing analyte sensor data
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US7097637B2 (en) 2003-08-27 2006-08-29 C. R. Bard, Inc. Safety needle with positive flush
CN101558992B (zh) 2003-09-02 2012-01-04 早出广司 葡萄糖传感器和葡萄糖浓度测定装置
US9133024B2 (en) 2003-09-03 2015-09-15 Brigitte Chau Phan Personal diagnostic devices including related methods and systems
KR20140134338A (ko) 2003-09-11 2014-11-21 테라노스, 인코포레이티드 피분석물의 모니터링 및 약물 전달을 위한 의료 기기
US7433727B2 (en) 2003-09-24 2008-10-07 Legacy Good Samaritan Hospital And Medical Center Implantable biosensor
JP4356088B2 (ja) 2003-09-26 2009-11-04 日本光電工業株式会社 多チャネル生体信号用テレメータシステム
ES2341963T3 (es) 2003-09-30 2010-06-30 F. Hoffmann-La Roche Ag Detector con biocompatibilidad mejorada.
US8140168B2 (en) 2003-10-02 2012-03-20 Medtronic, Inc. External power source for an implantable medical device having an adjustable carrier frequency and system and method related therefore
US7203549B2 (en) 2003-10-02 2007-04-10 Medtronic, Inc. Medical device programmer with internal antenna and display
USD579541S1 (en) * 2003-10-15 2008-10-28 Unomedical A/S Medical insertion device
WO2005037184A2 (en) 2003-10-21 2005-04-28 Novo Nordisk A/S Reservoir device with integrated mounting means
US7148803B2 (en) 2003-10-24 2006-12-12 Symbol Technologies, Inc. Radio frequency identification (RFID) based sensor networks
US20050090725A1 (en) 2003-10-28 2005-04-28 Joseph Page Disposable couplings for biometric instruments
US20050090607A1 (en) 2003-10-28 2005-04-28 Dexcom, Inc. Silicone composition for biocompatible membrane
EP1761880B1 (en) 2003-10-29 2013-02-27 Innovision Research & Technology PLC Rfid apparatus
US6928380B2 (en) 2003-10-30 2005-08-09 International Business Machines Corporation Thermal measurements of electronic devices during operation
US20050096516A1 (en) 2003-10-30 2005-05-05 Orhan Soykan Optical detector of organic analyte
US7299082B2 (en) 2003-10-31 2007-11-20 Abbott Diabetes Care, Inc. Method of calibrating an analyte-measurement device, and associated methods, devices and systems
US8095197B2 (en) 2003-11-03 2012-01-10 Microchips, Inc. Medical device for sensing glucose
US20090012376A1 (en) 2003-11-03 2009-01-08 Children's Medical Center Corporation Continuous Analyte Monitor and Method of Using Same
JP2005137416A (ja) 2003-11-04 2005-06-02 Sysmex Corp 経皮的分析物抽出システム及び経皮的分析物分析システム
US7419573B2 (en) 2003-11-06 2008-09-02 3M Innovative Properties Company Circuit for electrochemical sensor strip
CN1871046B (zh) 2003-11-06 2010-10-27 生命扫描有限公司 带有事件通知装置的药物配送笔
WO2005044116A2 (en) 2003-11-07 2005-05-19 Novo Nordisk A/S Cutting device for blunt needle
US7699807B2 (en) * 2003-11-10 2010-04-20 Smiths Medical Asd, Inc. Device and method for insertion of a cannula of an infusion device
US7731691B2 (en) 2003-11-10 2010-06-08 Smiths Medical Asd, Inc. Subcutaneous infusion device and device for insertion of a cannula of an infusion device and method
EP1684634A2 (en) 2003-11-12 2006-08-02 Facet Technologies, LLC Lancing device and multi-lancet cartridge
US8221332B2 (en) 2003-11-12 2012-07-17 Facet Technologies, Llc Multi-lancet cartridge and lancing device
DK1691679T3 (da) 2003-11-13 2010-11-22 Medtronic Minimed Inc Langtidsanalytsensorindretning
US20070106133A1 (en) 2003-11-18 2007-05-10 Satchwell Bruce R Monitoring of vital signs and performance levels
US8615282B2 (en) 2004-07-13 2013-12-24 Dexcom, Inc. Analyte sensor
WO2005051170A2 (en) 2003-11-19 2005-06-09 Dexcom, Inc. Integrated receiver for continuous analyte sensor
EP1687041A2 (en) 2003-11-20 2006-08-09 Angiotech International AG Soft tissue implants and anti-scarring agents
KR100519776B1 (ko) 2003-11-24 2005-10-07 삼성전자주식회사 영상 신호의 해상도 변환 방법 및 장치
US20050113886A1 (en) 2003-11-24 2005-05-26 Fischell David R. Implantable medical system with long range telemetry
US20050113648A1 (en) 2003-11-24 2005-05-26 Soohyun Yang Bidirectional monitoring system capable of a medical diagnosis and a commercial broadcast
US6850859B1 (en) 2003-12-03 2005-02-01 Watlow Electric Manufacturing Company Sensor drift compensation by lot
FR2863175A1 (fr) 2003-12-03 2005-06-10 Ela Medical Sa Dispositif medicale implantable actif a fonctions d'enregistrement holter
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US20100185071A1 (en) 2003-12-05 2010-07-22 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8425416B2 (en) 2006-10-04 2013-04-23 Dexcom, Inc. Analyte sensor
WO2005057168A2 (en) 2003-12-05 2005-06-23 Dexcom, Inc. Calibration techniques for a continuous analyte sensor
US8364230B2 (en) 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
US20080200788A1 (en) 2006-10-04 2008-08-21 Dexcorn, Inc. Analyte sensor
US8287453B2 (en) 2003-12-05 2012-10-16 Dexcom, Inc. Analyte sensor
US8425417B2 (en) 2003-12-05 2013-04-23 Dexcom, Inc. Integrated device for continuous in vivo analyte detection and simultaneous control of an infusion device
US20080197024A1 (en) 2003-12-05 2008-08-21 Dexcom, Inc. Analyte sensor
US8364231B2 (en) 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
ATE474219T1 (de) 2003-12-08 2010-07-15 Dexcom Inc Systeme und verfahren zur verbesserung elektrochemischer analytsensoren
EP3263032B1 (en) 2003-12-09 2024-01-24 Dexcom, Inc. Signal processing for continuous analyte sensor
JP4502634B2 (ja) * 2003-12-16 2010-07-14 テルモ株式会社 穿刺装置
US7763042B2 (en) 2003-12-16 2010-07-27 Panasonic Corporation Lancet for blood collection and puncture needle unit
WO2005058154A1 (en) 2003-12-16 2005-06-30 Medeikon Corporation Method for monitoring of analytes in biological samples using low coherence interferometry
ES2314476T3 (es) 2003-12-22 2009-03-16 Paul Hadvary Dispositivo sensor fijado dermicamente.
US7449024B2 (en) 2003-12-23 2008-11-11 Abbott Laboratories Suturing device with split arm and method of suturing tissue
US7384397B2 (en) 2003-12-30 2008-06-10 Medtronic Minimed, Inc. System and method for sensor recalibration
ES2294531T3 (es) 2003-12-30 2008-04-01 Disetronic Licensing Ag Dispositivo de insercion para dispositivos de perforacion.
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
GB2409951A (en) 2004-01-08 2005-07-13 Remote Diagnostic Technologies Wireless local area network of medical sensors
US7637868B2 (en) 2004-01-12 2009-12-29 Dexcom, Inc. Composite material for implantable device
WO2005068006A1 (ja) * 2004-01-16 2005-07-28 Kabushiki Kaisha Top 留置針
CN1910600B (zh) 2004-01-23 2011-12-14 株式会社半导体能源研究所 Id标记、id卡和id标签
PL1709750T3 (pl) 2004-01-27 2015-03-31 Altivera L L C Diagnostyczne czujniki identyfikacji radiowej i ich zastosowanie
JP4526827B2 (ja) 2004-02-03 2010-08-18 オムロンヘルスケア株式会社 電子血圧計
US8465696B2 (en) 2004-02-03 2013-06-18 Polymer Technology Systems, Inc. Dry test strip with controlled flow and method of manufacturing same
US8165651B2 (en) 2004-02-09 2012-04-24 Abbott Diabetes Care Inc. Analyte sensor, and associated system and method employing a catalytic agent
US7699964B2 (en) 2004-02-09 2010-04-20 Abbott Diabetes Care Inc. Membrane suitable for use in an analyte sensor, analyte sensor, and associated method
US7364592B2 (en) 2004-02-12 2008-04-29 Dexcom, Inc. Biointerface membrane with macro-and micro-architecture
EP1718198A4 (en) 2004-02-17 2008-06-04 Therasense Inc METHOD AND SYSTEM FOR PROVIDING DATA COMMUNICATION IN A CONTINUOUS BLOOD SUGAR MONITORING AND MANAGEMENT SYSTEM
US20060154642A1 (en) 2004-02-20 2006-07-13 Scannell Robert F Jr Medication & health, environmental, and security monitoring, alert, intervention, information and network system with associated and supporting apparatuses
JP2007526807A (ja) 2004-02-23 2007-09-20 エシコン・インコーポレイテッド 診断テスト装置
JP3590053B1 (ja) 2004-02-24 2004-11-17 株式会社日立製作所 血糖値測定装置
JP4593129B2 (ja) 2004-02-26 2010-12-08 オリンパス株式会社 内視鏡
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
WO2005084257A2 (en) 2004-02-26 2005-09-15 Vpn Solutions, Llc Composite thin-film glucose sensor
WO2005084557A1 (en) 2004-03-02 2005-09-15 Facet Technologies, Llc Compact multi-use lancing device
US7039538B2 (en) 2004-03-08 2006-05-02 Nellcor Puritant Bennett Incorporated Pulse oximeter with separate ensemble averaging for oxygen saturation and heart rate
DE102004011135A1 (de) 2004-03-08 2005-09-29 Disetronic Licensing Ag Verfahren und Vorrichtung zum Berechnen einer Bolusmenge
GB0405798D0 (en) 2004-03-15 2004-04-21 E San Ltd Medical data display
US7228182B2 (en) 2004-03-15 2007-06-05 Cardiac Pacemakers, Inc. Cryptographic authentication for telemetry with an implantable medical device
US7831828B2 (en) 2004-03-15 2010-11-09 Cardiac Pacemakers, Inc. System and method for securely authenticating a data exchange session with an implantable medical device
DK1734858T3 (da) 2004-03-22 2014-10-20 Bodymedia Inc Ikke-invasiv temperaturovervågningsindretning
JP2007535974A (ja) 2004-03-26 2007-12-13 ノボ・ノルデイスク・エー／エス 糖尿病患者の関連データの表示装置
US20050221504A1 (en) 2004-04-01 2005-10-06 Petruno Patrick T Optoelectronic rapid diagnostic test system
US6971274B2 (en) 2004-04-02 2005-12-06 Sierra Instruments, Inc. Immersible thermal mass flow meter
US20050222518A1 (en) 2004-04-06 2005-10-06 Genocell, Llc Biopsy and injection catheters
US20060009727A1 (en) 2004-04-08 2006-01-12 Chf Solutions Inc. Method and apparatus for an extracorporeal control of blood glucose
US7985222B2 (en) 2004-04-21 2011-07-26 Medshape Solutions, Inc. Osteosynthetic implants and methods of use and manufacture
US7815569B2 (en) 2004-04-21 2010-10-19 University Of Virginia Patent Foundation Method, system and computer program product for evaluating the accuracy of blood glucose monitoring sensors/devices
US7324850B2 (en) 2004-04-29 2008-01-29 Cardiac Pacemakers, Inc. Method and apparatus for communication between a handheld programmer and an implantable medical device
BRPI0510550A (pt) 2004-05-03 2007-11-20 Ams Res Corp implante cirúrgico, kit cirúrgico, método para formar ou montar um implante cirúrgico, molde de inserção, aparelho, e, método para produzir um implante cirúrgico
US9101302B2 (en) 2004-05-03 2015-08-11 Abbott Diabetes Care Inc. Analyte test device
US8277713B2 (en) 2004-05-03 2012-10-02 Dexcom, Inc. Implantable analyte sensor
US8792955B2 (en) 2004-05-03 2014-07-29 Dexcom, Inc. Transcutaneous analyte sensor
US20050245799A1 (en) 2004-05-03 2005-11-03 Dexcom, Inc. Implantable analyte sensor
US9380975B2 (en) 2004-05-07 2016-07-05 Becton, Dickinson And Company Contact activated lancet device
US7333013B2 (en) 2004-05-07 2008-02-19 Berger J Lee Medical implant device with RFID tag and method of identification of device
US7651845B2 (en) 2004-05-13 2010-01-26 The Regents Of The University Of California Method and apparatus for glucose control and insulin dosing for diabetics
US7727147B1 (en) 2004-05-14 2010-06-01 Flint Hills Scientific Llc Method and system for implantable glucose monitoring and control of a glycemic state of a subject
US7241266B2 (en) 2004-05-20 2007-07-10 Digital Angel Corporation Transducer for embedded bio-sensor using body energy as a power source
US7842046B1 (en) 2004-05-26 2010-11-30 Granit Medical Innovations, Llc Endoscopic sewing device and associated method
US6999854B2 (en) 2004-05-28 2006-02-14 International Business Machines Corporation Medical infusion pump capable of learning bolus time patterns and providing bolus alerts
EP1765455A2 (en) 2004-06-01 2007-03-28 Microchips, Inc. Devices and methods for measuring and enhancing drug or analyte transport to/from medical implant
US7118667B2 (en) 2004-06-02 2006-10-10 Jin Po Lee Biosensors having improved sample application and uses thereof
CA3090413C (en) 2004-06-04 2023-10-10 Abbott Diabetes Care Inc. Glucose monitoring and graphical representations in a data management system
US7289855B2 (en) 2004-06-09 2007-10-30 Medtronic, Inc. Implantable medical device package antenna
US7283867B2 (en) 2004-06-10 2007-10-16 Ndi Medical, Llc Implantable system and methods for acquisition and processing of electrical signals from muscles and/or nerves and/or central nervous system tissue
US20070100222A1 (en) 2004-06-14 2007-05-03 Metronic Minimed, Inc. Analyte sensing apparatus for hospital use
US7299081B2 (en) 2004-06-15 2007-11-20 Abbott Laboratories Analyte test device
US7585287B2 (en) 2004-06-16 2009-09-08 Smiths Medical Md, Inc. Device and method for insertion of a cannula of an infusion device
US7519430B2 (en) 2004-06-17 2009-04-14 Cardiac Pacemakers, Inc. Dynamic telemetry encoding for an implantable medical device
US7457669B2 (en) 2004-06-17 2008-11-25 Cardiac Pacemakers, Inc. On-demand retransmission of data with an implantable medical device
WO2006002178A1 (en) 2004-06-18 2006-01-05 Novartis Vaccines And Diagnostics Inc. Methods of treatment of endobronchial infections
US7565197B2 (en) 2004-06-18 2009-07-21 Medtronic, Inc. Conditional requirements for remote medical device programming
US7556723B2 (en) 2004-06-18 2009-07-07 Roche Diagnostics Operations, Inc. Electrode design for biosensor
JP2006005774A (ja) 2004-06-18 2006-01-05 Alps Electric Co Ltd 通信端末装置
US7623988B2 (en) 2004-06-23 2009-11-24 Cybiocare Inc. Method and apparatus for the monitoring of clinical states
IL162761A (en) 2004-06-28 2013-04-30 Avraham Shekalim A device for continuous glucose measurement in body fluids
DE102004031092A1 (de) 2004-06-28 2006-01-12 Giesecke & Devrient Gmbh Transpondereinheit
US20060001551A1 (en) 2004-06-30 2006-01-05 Ulrich Kraft Analyte monitoring system with wireless alarm
US20060001538A1 (en) 2004-06-30 2006-01-05 Ulrich Kraft Methods of monitoring the concentration of an analyte
JP2008504893A (ja) 2004-06-30 2008-02-21 ファセット・テクノロジーズ・エルエルシー 穿刺装置及びマルチランセットカートリッジ
US8343074B2 (en) 2004-06-30 2013-01-01 Lifescan Scotland Limited Fluid handling devices
US7394382B2 (en) 2004-07-01 2008-07-01 Power Id Battery-assisted backscatter RFID transponder
US20060015020A1 (en) 2004-07-06 2006-01-19 Dexcom, Inc. Systems and methods for manufacture of an analyte-measuring device including a membrane system
US20060016700A1 (en) 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
ATE548971T1 (de) 2004-07-13 2012-03-15 Dexcom Inc Transkutaner analytsensor
WO2006127694A2 (en) 2004-07-13 2006-11-30 Dexcom, Inc. Analyte sensor
US7783333B2 (en) 2004-07-13 2010-08-24 Dexcom, Inc. Transcutaneous medical device with variable stiffness
US8452368B2 (en) 2004-07-13 2013-05-28 Dexcom, Inc. Transcutaneous analyte sensor
US20080242961A1 (en) 2004-07-13 2008-10-02 Dexcom, Inc. Transcutaneous analyte sensor
US8565848B2 (en) 2004-07-13 2013-10-22 Dexcom, Inc. Transcutaneous analyte sensor
US7344500B2 (en) 2004-07-27 2008-03-18 Medtronic Minimed, Inc. Sensing system with auxiliary display
US8313433B2 (en) 2004-08-06 2012-11-20 Medtronic Minimed, Inc. Medical data management system and process
WO2006015922A1 (en) 2004-08-10 2006-02-16 Novo Nordisk A/S A method of forming a sterilised sensor package and a sterilised sensor package
US7567841B2 (en) * 2004-08-20 2009-07-28 Cardiac Pacemakers, Inc. Method and apparatus for delivering combined electrical and drug therapies
WO2006026748A1 (en) 2004-08-31 2006-03-09 Lifescan Scotland Limited Method of manufacturing an auto-calibrating sensor
EP1630898A1 (en) 2004-08-31 2006-03-01 Eidgenössische Technische Hochschule (ETH) Textile antenna
US7214189B2 (en) 2004-09-02 2007-05-08 Proteus Biomedical, Inc. Methods and apparatus for tissue activation and monitoring
US20080312859A1 (en) 2004-09-03 2008-12-18 Novo Nordisk A/S Method of Calibrating a System for Measuring the Concentration of Substances in Body and an Apparatus for Exercising the Method
US7468033B2 (en) 2004-09-08 2008-12-23 Medtronic Minimed, Inc. Blood contacting sensor
US9820658B2 (en) 2006-06-30 2017-11-21 Bao Q. Tran Systems and methods for providing interoperability among healthcare devices
US8211038B2 (en) 2004-09-17 2012-07-03 Abbott Diabetes Care Inc. Multiple-biosensor article
US20090247931A1 (en) 2004-09-23 2009-10-01 Novo Nordisk A/S Device for self-care support
JP2008515275A (ja) 2004-09-27 2008-05-08 アギア システムズ インコーポレーテッド 立体的イメージ作成機能を有する移動通信装置
DE102004048864A1 (de) 2004-10-07 2006-04-13 Roche Diagnostics Gmbh Analytisches Testelement mit drahtloser Datenübertragung
US20090048499A1 (en) 2004-10-18 2009-02-19 Novo Nordisk A/S Sensor film for transcutaneous insertion and a method for making the sensor film
US8224414B2 (en) 2004-10-28 2012-07-17 Echo Therapeutics, Inc. System and method for analyte sampling and analysis with hydrogel
EP1827213B1 (en) 2004-11-02 2010-12-08 Medtronic, Inc. Apparatus for data retention in an implantable medical device
US7408132B2 (en) 2004-11-08 2008-08-05 Rrc Power Solutions Gmbh Temperature sensor for power supply
EP1813085B1 (en) 2004-11-19 2009-09-23 Sensormatic Electronics Corporation Technique and hardware for communicating with backscatter radio frequency identification readers
CA2586525C (en) 2004-11-22 2013-01-15 Intelliject, Llc Devices, systems, and methods for medicament delivery
US7237712B2 (en) 2004-12-01 2007-07-03 Alfred E. Mann Foundation For Scientific Research Implantable device and communication integrated circuit implementable therein
US20070010950A1 (en) 2004-12-03 2007-01-11 Abensour Daniel S Method to determine the degree and stability of blood glucose control in patients with diabetes mellitus via the creation and continuous update of new statistical indicators in blood glucose monitors or free standing computers
US20090048563A1 (en) 2004-12-06 2009-02-19 Novo Nordisk A/S Ventilated Skin Mountable Device
EP1669020A1 (de) 2004-12-07 2006-06-14 Roche Diagnostics GmbH Aufbewahrungstasche mit integrierten Funktionen
DE102004059491B4 (de) 2004-12-10 2008-11-06 Roche Diagnostics Gmbh Lanzettenvorrichtung zum Erzeugen einer Einstichwunde und Lanzettenantriebs-Baugruppe
ATE545361T1 (de) 2004-12-13 2012-03-15 Koninkl Philips Electronics Nv Mobile überwachung
US7461192B2 (en) 2004-12-15 2008-12-02 Rambus Inc. Interface for bridging out-of-band information and preventing false presence detection of terminating devices
US7568619B2 (en) 2004-12-15 2009-08-04 Alcon, Inc. System and method for identifying and controlling ophthalmic surgical devices and components
US20070027381A1 (en) 2005-07-29 2007-02-01 Therasense, Inc. Inserter and methods of use
US20090105569A1 (en) 2006-04-28 2009-04-23 Abbott Diabetes Care, Inc. Introducer Assembly and Methods of Use
US9572534B2 (en) 2010-06-29 2017-02-21 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
US8029441B2 (en) 2006-02-28 2011-10-04 Abbott Diabetes Care Inc. Analyte sensor transmitter unit configuration for a data monitoring and management system
US8333714B2 (en) 2006-09-10 2012-12-18 Abbott Diabetes Care Inc. Method and system for providing an integrated analyte sensor insertion device and data processing unit
US20090082693A1 (en) 2004-12-29 2009-03-26 Therasense, Inc. Method and apparatus for providing temperature sensor module in a data communication system
US8512243B2 (en) 2005-09-30 2013-08-20 Abbott Diabetes Care Inc. Integrated introducer and transmitter assembly and methods of use
US10226207B2 (en) 2004-12-29 2019-03-12 Abbott Diabetes Care Inc. Sensor inserter having introducer
US9636450B2 (en) 2007-02-19 2017-05-02 Udo Hoss Pump system modular components for delivering medication and analyte sensing at seperate insertion sites
US9351669B2 (en) 2009-09-30 2016-05-31 Abbott Diabetes Care Inc. Interconnect for on-body analyte monitoring device
US9398882B2 (en) 2005-09-30 2016-07-26 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor and data processing device
US7883464B2 (en) 2005-09-30 2011-02-08 Abbott Diabetes Care Inc. Integrated transmitter unit and sensor introducer mechanism and methods of use
CN101137320B (zh) 2004-12-29 2012-10-03 生命扫描苏格兰有限公司 将数据输入到分析物测试装置的方法
US7697967B2 (en) 2005-12-28 2010-04-13 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US8571624B2 (en) 2004-12-29 2013-10-29 Abbott Diabetes Care Inc. Method and apparatus for mounting a data transmission device in a communication system
US7731657B2 (en) 2005-08-30 2010-06-08 Abbott Diabetes Care Inc. Analyte sensor introducer and methods of use
US9259175B2 (en) 2006-10-23 2016-02-16 Abbott Diabetes Care, Inc. Flexible patch for fluid delivery and monitoring body analytes
US20110073475A1 (en) 2009-08-29 2011-03-31 Abbott Diabetes Care Inc. Analyte Sensor
US7470237B2 (en) 2005-01-10 2008-12-30 Ethicon Endo-Surgery, Inc. Biopsy instrument with improved needle penetration
US20060166629A1 (en) 2005-01-24 2006-07-27 Therasense, Inc. Method and apparatus for providing EMC Class-B compliant RF transmitter for data monitoring an detection systems
US20060173260A1 (en) 2005-01-31 2006-08-03 Gmms Ltd System, device and method for diabetes treatment and monitoring
US7547281B2 (en) 2005-02-01 2009-06-16 Medtronic Minimed, Inc. Algorithm sensor augmented bolus estimator for semi-closed loop infusion system
US7545272B2 (en) 2005-02-08 2009-06-09 Therasense, Inc. RF tag on test strips, test strip vials and boxes
US7499002B2 (en) 2005-02-08 2009-03-03 International Business Machines Corporation Retractable string interface for stationary and portable devices
US8435289B2 (en) * 2005-02-11 2013-05-07 Abbott Medical Optics Inc. Rapid exchange IOL insertion apparatus and methods of using
US20090030293A1 (en) 2005-02-11 2009-01-29 The University Court Of The University Of Glasgow Sensing device, apparatus and system, and method for operating the same
US20060181695A1 (en) 2005-02-11 2006-08-17 Sage Burton H Jr Compensating liquid delivery system and method
KR100638727B1 (ko) 2005-02-28 2006-10-30 삼성전기주식회사 Ｚｉｇｂｅｅ 및 불루투스 겸용 송수신기
EP1698279A1 (de) † 2005-03-04 2006-09-06 Disetronic Licensing AG Sequentielle Einführung von Hauptpenetratoren
CN101163440B (zh) 2005-03-09 2010-06-16 库蒂森斯股份公司 嵌入有微电子系统的三维粘合剂器件
CA2600427C (en) 2005-03-09 2013-09-10 Coloplast A/S A three-dimensional adhesive device having a microelectronic system embedded therein
US20090076360A1 (en) 2007-09-13 2009-03-19 Dexcom, Inc. Transcutaneous analyte sensor
US8133178B2 (en) 2006-02-22 2012-03-13 Dexcom, Inc. Analyte sensor
US20060202805A1 (en) 2005-03-14 2006-09-14 Alfred E. Mann Foundation For Scientific Research Wireless acquisition and monitoring system
AU2006222889A1 (en) 2005-03-15 2006-09-21 Entelos, Inc. Apparatus and method for computer modeling type 1 diabetes
WO2006102412A2 (en) 2005-03-21 2006-09-28 Abbott Diabetes Care, Inc. Method and system for providing integrated medication infusion and analyte monitoring system
JP2006280464A (ja) 2005-03-31 2006-10-19 Semiconductor Energy Lab Co Ltd 生体情報検知装置、健康管理装置、およびそれらを用いた健康管理支援システム、ならびに健康管理支援方法
US7889069B2 (en) 2005-04-01 2011-02-15 Codman & Shurtleff, Inc. Wireless patient monitoring system
WO2006110742A2 (en) 2005-04-07 2006-10-19 Becton, Dickinson And Company Lancet device
DE502005002216D1 (de) 2005-04-08 2008-01-24 Roche Diagnostics Gmbh Vorrichtung zur Platzierung einer Sonde in lebendem Gewebe
JP4718882B2 (ja) 2005-04-08 2011-07-06 株式会社日立製作所 センサノード
US20090054753A1 (en) 2007-08-21 2009-02-26 Mark Ries Robinson Variable Sampling Interval for Blood Analyte Determinations
WO2006108809A1 (en) 2005-04-13 2006-10-19 Novo Nordisk A/S Medical skin mountable device and system
US8060174B2 (en) 2005-04-15 2011-11-15 Dexcom, Inc. Analyte sensing biointerface
US7270633B1 (en) 2005-04-22 2007-09-18 Cardiac Pacemakers, Inc. Ambulatory repeater for use in automated patient care and method thereof
DE102005019306B4 (de) 2005-04-26 2011-09-01 Disetronic Licensing Ag Energieoptimierte Datenübertragung eines medizinischen Geräts
US8036853B2 (en) 2005-04-26 2011-10-11 Emerson Climate Technologies, Inc. Compressor memory system and method
GB2425601B (en) 2005-04-26 2008-01-30 Bio Nano Sensium Technologies Sensor configuration
US8700157B2 (en) 2005-04-29 2014-04-15 Medtronic, Inc. Telemetry head programmer for implantable medical device and system and method
US8112240B2 (en) 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
US7467065B2 (en) 2005-05-02 2008-12-16 Home Diagnostics, Inc. Computer interface for diagnostic meter
US7641649B2 (en) 2005-05-06 2010-01-05 Medtronic Minimed, Inc. Reservoir support and method for infusion device
US20060253085A1 (en) 2005-05-06 2006-11-09 Medtronic Minimed, Inc. Dual insertion set
US7905868B2 (en) 2006-08-23 2011-03-15 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
ES2820430T3 (es) 2005-05-09 2021-04-21 Labrador Diagnostics Llc Sistemas de fluidos para centros de atención y usos de los mismos
US7604178B2 (en) 2005-05-11 2009-10-20 Intelleflex Corporation Smart tag activation
WO2006124716A2 (en) 2005-05-13 2006-11-23 Trustees Of Boston University Fully automated control system for type 1 diabetes
US7541935B2 (en) 2005-05-19 2009-06-02 Proacticare Llc System and methods for monitoring caregiver performance
TWI265677B (en) 2005-06-01 2006-11-01 Bionime Corp Coding module, bio measuring meter and system for operating bio measuring meter
DE602006016266D1 (de) 2005-06-02 2010-09-30 Isense Corp Verwendung von mehrfachen datenpunkten und filterung in einem analytsensor
US20080071580A1 (en) 2005-06-03 2008-03-20 Marcus Alan O System and method for medical evaluation and monitoring
US20070033074A1 (en) 2005-06-03 2007-02-08 Medtronic Minimed, Inc. Therapy management system
US20060272652A1 (en) 2005-06-03 2006-12-07 Medtronic Minimed, Inc. Virtual patient software system for educating and treating individuals with diabetes
US7620437B2 (en) 2005-06-03 2009-11-17 Abbott Diabetes Care Inc. Method and apparatus for providing rechargeable power in data monitoring and management systems
US20060276771A1 (en) 2005-06-06 2006-12-07 Galley Paul J System and method providing for user intervention in a diabetes control arrangement
JP4240007B2 (ja) 2005-06-06 2009-03-18 ニプロ株式会社 遠隔医療システム
US7387607B2 (en) 2005-06-06 2008-06-17 Intel Corporation Wireless medical sensor system
US20060282042A1 (en) 2005-06-08 2006-12-14 Sensors For Medicine And Science, Inc. Insertion device and method
JP2006344447A (ja) 2005-06-08 2006-12-21 Kokusan Denki Co Ltd 車載用バッテリ・電気ユニット組合せ構造体
EP2260759B1 (de) 2005-06-17 2015-05-06 F. Hoffmann-La Roche AG Sensorsystem sowie Anordnung und Verfahren zur Überwachung eines Inhaltsstoffs, insbesondere Glucose in Körpergewebe
US20070016449A1 (en) 2005-06-29 2007-01-18 Gary Cohen Flexible glucose analysis using varying time report deltas and configurable glucose target ranges
WO2007008646A2 (en) 2005-07-12 2007-01-18 Massachusetts Institute Of Technology Wireless non-radiative energy transfer
WO2007007459A1 (ja) 2005-07-12 2007-01-18 Omron Healthcare Co., Ltd. 生体の成分に関する情報を正確に測定できる生化学計測器
US7413124B2 (en) 2005-07-19 2008-08-19 3M Innovative Properties Company RFID reader supporting one-touch search functionality
TWI417543B (zh) 2005-08-05 2013-12-01 Bayer Healthcare Llc 具有一包含複數個預定使用者特徵位準之多重位準使用者介面之計量器及其使用方法
US20070060869A1 (en) 2005-08-16 2007-03-15 Tolle Mike C V Controller device for an infusion pump
US20070093786A1 (en) 2005-08-16 2007-04-26 Medtronic Minimed, Inc. Watch controller for a medical device
US20070111196A1 (en) 2005-08-19 2007-05-17 Javier Alarcon Sterilization of Biosensors
EP1758039A1 (de) 2005-08-27 2007-02-28 Roche Diagnostics GmbH Kommunikations-Adapter für ambulante medizinische oder therapeutische Geräte
US20070060801A1 (en) 2005-08-31 2007-03-15 Isense Corporation Transcutaneous introducer assembly
US8831735B2 (en) 2005-08-31 2014-09-09 Michael Sasha John Methods and systems for semi-automatic adjustment of medical monitoring and treatment
US9089713B2 (en) 2005-08-31 2015-07-28 Michael Sasha John Methods and systems for semi-automatic adjustment of medical monitoring and treatment
WO2007028271A2 (en) 2005-09-09 2007-03-15 F. Hoffmann-La Roche Ag A system, tools, devices and a program for diabetes care
US8298389B2 (en) 2005-09-12 2012-10-30 Abbott Diabetes Care Inc. In vitro analyte sensor, and methods
PT1762259E (pt) 2005-09-12 2010-12-10 Unomedical As Insersor para um conjunto de infusão com uma primeira e uma segunda unidades de mola
DE502005009907D1 (de) 2005-09-15 2010-08-26 Roche Diagnostics Gmbh Insertionskopf mit Griff
DK1764125T5 (da) † 2005-09-15 2011-11-14 Hoffmann La Roche System bestående af indsættelseshoved og indsættelsesapparat
US8202249B2 (en) 2005-09-20 2012-06-19 Panasonic Corporation Injection device with puncture function, method for controlling injection device with puncture function, chemical solution administration device, and method for controlling chemical solution administration device
US7725148B2 (en) 2005-09-23 2010-05-25 Medtronic Minimed, Inc. Sensor with layered electrodes
US9072476B2 (en) 2005-09-23 2015-07-07 Medtronic Minimed, Inc. Flexible sensor apparatus
US7534226B2 (en) 2005-09-26 2009-05-19 M2 Group Holdings, Inc. Dispensing fluid from an infusion pump system
US7846311B2 (en) 2005-09-27 2010-12-07 Abbott Diabetes Care Inc. In vitro analyte sensor and methods of use
US7761165B1 (en) 2005-09-29 2010-07-20 Boston Scientific Neuromodulation Corporation Implantable stimulator with integrated plastic housing/metal contacts and manufacture and use
US9521968B2 (en) 2005-09-30 2016-12-20 Abbott Diabetes Care Inc. Analyte sensor retention mechanism and methods of use
US7756561B2 (en) 2005-09-30 2010-07-13 Abbott Diabetes Care Inc. Method and apparatus for providing rechargeable power in data monitoring and management systems
US8880138B2 (en) † 2005-09-30 2014-11-04 Abbott Diabetes Care Inc. Device for channeling fluid and methods of use
US7550053B2 (en) 2006-01-26 2009-06-23 Ilh, Llc Catheters with lubricious linings and methods for making and using them
US7468125B2 (en) 2005-10-17 2008-12-23 Lifescan, Inc. System and method of processing a current sample for calculating a glucose concentration
IL178557A0 (en) 2005-10-19 2007-02-11 Animas Corp Safety infusion set
US7701052B2 (en) 2005-10-21 2010-04-20 E. I. Du Pont De Nemours And Company Power core devices
JP4866424B2 (ja) 2005-10-25 2012-02-01 キャディ サイエンティフィック プライベート リミテッド 少なくとも一つの生理的パラメータを測定及び追跡するためのシステム及びそうするための測定デバイス
US7486977B2 (en) 2005-10-27 2009-02-03 Smiths Medical Pm, Inc. Single use pulse oximeter
US20090054747A1 (en) 2005-10-31 2009-02-26 Abbott Diabetes Care, Inc. Method and system for providing analyte sensor tester isolation
US20070095661A1 (en) 2005-10-31 2007-05-03 Yi Wang Method of making, and, analyte sensor
AU2006311708A1 (en) 2005-11-03 2007-05-18 Patton Medical Devices, Lp Fluid delivery devices, systems and methods
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
US8182444B2 (en) 2005-11-04 2012-05-22 Medrad, Inc. Delivery of agents such as cells to tissue
DK1951340T4 (en) 2005-11-08 2017-05-22 Bigfoot Biomedical Inc infusion pump
WO2007056592A2 (en) 2005-11-08 2007-05-18 M2 Medical A/S Method and system for manual and autonomous control of an infusion pump
US20070173706A1 (en) 2005-11-11 2007-07-26 Isense Corporation Method and apparatus for insertion of a sensor
US9615851B2 (en) 2005-11-11 2017-04-11 Waveform Technologies, Inc. Method and apparatus for insertion of a sensor
US7918975B2 (en) 2005-11-17 2011-04-05 Abbott Diabetes Care Inc. Analytical sensors for biological fluid
US7729737B2 (en) 2005-11-22 2010-06-01 Isense Corporation Method and apparatus for background current arrangements for a biosensor
US20070168224A1 (en) 2005-11-22 2007-07-19 Letzt Alan M Advanced diabetes management system (adms)
US8815175B2 (en) 2005-11-30 2014-08-26 Abbott Diabetes Care Inc. Integrated meter for analyzing biological samples
CN101336092A (zh) * 2005-12-01 2008-12-31 爱科来株式会社 传感器-刺血针一体型器件、以及使用其的体液采集方法
US7963917B2 (en) 2005-12-05 2011-06-21 Echo Therapeutics, Inc. System and method for continuous non-invasive glucose monitoring
US7941200B2 (en) 2005-12-08 2011-05-10 Roche Diagnostics Operations, Inc. System and method for determining drug administration information
WO2007065944A1 (en) 2005-12-08 2007-06-14 Novo Nordisk A/S Medical system comprising a sensor device
JP5044115B2 (ja) 2005-12-09 2012-10-10 佳彦 平尾 測定システム、情報端末およびプログラム
US7643798B2 (en) 2005-12-09 2010-01-05 Sony Ericsson Mobile Communications Ab Passive NFC activation of short distance wireless communication
US8947233B2 (en) 2005-12-09 2015-02-03 Tego Inc. Methods and systems of a multiple radio frequency network node RFID tag
US11298058B2 (en) 2005-12-28 2022-04-12 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US8515518B2 (en) 2005-12-28 2013-08-20 Abbott Diabetes Care Inc. Analyte monitoring
WO2007120363A2 (en) 2005-12-28 2007-10-25 Abbott Diabetes Care, Inc. Medical device insertion
US8160670B2 (en) 2005-12-28 2012-04-17 Abbott Diabetes Care Inc. Analyte monitoring: stabilizer for subcutaneous glucose sensor with incorporated antiglycolytic agent
US8102789B2 (en) 2005-12-29 2012-01-24 Medtronic, Inc. System and method for synchronous wireless communication with a medical device
WO2007084516A2 (en) 2006-01-18 2007-07-26 Dexcom, Inc. Membranes for an analyte sensor
US20070179349A1 (en) 2006-01-19 2007-08-02 Hoyme Kenneth P System and method for providing goal-oriented patient management based upon comparative population data analysis
US7574266B2 (en) 2006-01-19 2009-08-11 Medtronic, Inc. System and method for telemetry with an implantable medical device
WO2007089738A2 (en) 2006-01-26 2007-08-09 The Regents Of The University Of Michigan Microelectrode with laterally extending platform for reduction of tissue encapsulation
US7736310B2 (en) 2006-01-30 2010-06-15 Abbott Diabetes Care Inc. On-body medical device securement
US7872574B2 (en) 2006-02-01 2011-01-18 Innovation Specialists, Llc Sensory enhancement systems and methods in personal electronic devices
MX2008010341A (es) 2006-02-09 2008-11-18 Deka Products Lp Sistemas y metodos adhesivos y perifericos para dispositivos medicos.
WO2007093981A2 (en) 2006-02-15 2007-08-23 Medingo Ltd. Systems and methods for sensing analyte and dispensing therapeutic fluid
EP1986543B2 (en) 2006-02-22 2022-03-09 DexCom, Inc. Analyte sensor
US7826902B2 (en) 2006-02-24 2010-11-02 Medtronic, Inc. User interface with 2D views for configuring stimulation therapy
CA2630550A1 (en) 2006-02-27 2007-09-07 Edwards Lifesciences Corporation Flux limiting membrane for intravenous amperometric biosensor
US7826879B2 (en) 2006-02-28 2010-11-02 Abbott Diabetes Care Inc. Analyte sensors and methods of use
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
US7811430B2 (en) 2006-02-28 2010-10-12 Abbott Diabetes Care Inc. Biosensors and methods of making
US7576657B2 (en) 2006-03-22 2009-08-18 Symbol Technologies, Inc. Single frequency low power RFID device
US7887682B2 (en) 2006-03-29 2011-02-15 Abbott Diabetes Care Inc. Analyte sensors and methods of use
US20070233013A1 (en) 2006-03-31 2007-10-04 Schoenberg Stephen J Covers for tissue engaging members
US9392969B2 (en) 2008-08-31 2016-07-19 Abbott Diabetes Care Inc. Closed loop control and signal attenuation detection
US9675290B2 (en) 2012-10-30 2017-06-13 Abbott Diabetes Care Inc. Sensitivity calibration of in vivo sensors used to measure analyte concentration
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
US8346335B2 (en) 2008-03-28 2013-01-01 Abbott Diabetes Care Inc. Analyte sensor calibration management
US8374668B1 (en) 2007-10-23 2013-02-12 Abbott Diabetes Care Inc. Analyte sensor with lag compensation
US8473022B2 (en) 2008-01-31 2013-06-25 Abbott Diabetes Care Inc. Analyte sensor with time lag compensation
US7618369B2 (en) 2006-10-02 2009-11-17 Abbott Diabetes Care Inc. Method and system for dynamically updating calibration parameters for an analyte sensor
US8219173B2 (en) 2008-09-30 2012-07-10 Abbott Diabetes Care Inc. Optimizing analyte sensor calibration
US8140312B2 (en) 2007-05-14 2012-03-20 Abbott Diabetes Care Inc. Method and system for determining analyte levels
US7653425B2 (en) 2006-08-09 2010-01-26 Abbott Diabetes Care Inc. Method and system for providing calibration of an analyte sensor in an analyte monitoring system
US8583205B2 (en) 2008-03-28 2013-11-12 Abbott Diabetes Care Inc. Analyte sensor calibration management
US7801582B2 (en) 2006-03-31 2010-09-21 Abbott Diabetes Care Inc. Analyte monitoring and management system and methods therefor
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
US20070231846A1 (en) 2006-04-03 2007-10-04 Cosentino Daniel L Glucose meter communication method and system
US7559899B2 (en) 2006-04-12 2009-07-14 Salutron, Inc. Power saving techniques for continuous heart rate monitoring
WO2007145708A2 (en) 2006-04-19 2007-12-21 Underwater Kinetics, Llp Methods and devices that employ thermal control of current to electrical components
DE602006010603D1 (de) 2006-04-20 2009-12-31 Lifescan Scotland Ltd Verfarhen zum senden von daten in einem blutglucos
US7359837B2 (en) 2006-04-27 2008-04-15 Medtronic, Inc. Peak data retention of signal data in an implantable medical device
US20070255125A1 (en) 2006-04-28 2007-11-01 Moberg Sheldon B Monitor devices for networked fluid infusion systems
US20070258395A1 (en) 2006-04-28 2007-11-08 Medtronic Minimed, Inc. Wireless data communication protocols for a medical device network
US20070255126A1 (en) 2006-04-28 2007-11-01 Moberg Sheldon B Data communication in networked fluid infusion systems
US8380300B2 (en) 2006-04-28 2013-02-19 Medtronic, Inc. Efficacy visualization
US20070253021A1 (en) 2006-04-28 2007-11-01 Medtronic Minimed, Inc. Identification of devices in a medical device network and wireless data communication techniques utilizing device identifiers
BRPI0711105A2 (pt) 2006-05-02 2011-08-23 3M Innovative Properties Co sistema de monitoramento para recinto de equipamentos de telecomunicação
GB0608829D0 (en) 2006-05-04 2006-06-14 Husheer Shamus L G In-situ measurement of physical parameters
EP2015804B1 (de) 2006-05-10 2019-02-13 F. Hoffmann-La Roche AG Infusionsset mit einer datenspeichervorrichtung
DE102006023213B3 (de) 2006-05-17 2007-09-27 Siemens Ag Betriebsverfahren für einen Geber und eine mit dem Geber kommunizierende Steuereinrichtung
DE502007000495D1 (de) 2006-05-19 2009-04-23 Roche Diagnostics Gmbh Adaptervorrichtung für das Ankleben eines medizinischen Geräts an die Hautoberfläche
DE102006025485B4 (de) 2006-05-30 2008-03-20 Polylc Gmbh & Co. Kg Antennenanordnung sowie deren Verwendung
US20090054749A1 (en) 2006-05-31 2009-02-26 Abbott Diabetes Care, Inc. Method and System for Providing Data Transmission in a Data Management System
AU2007256561B2 (en) 2006-06-07 2012-07-19 Unomedical A/S Inserter for transcutaneous sensor
WO2007143225A2 (en) 2006-06-07 2007-12-13 Abbott Diabetes Care, Inc. Analyte monitoring system and method
US8098159B2 (en) 2006-06-09 2012-01-17 Intelleflex Corporation RF device comparing DAC output to incoming signal for selectively performing an action
US7796038B2 (en) 2006-06-12 2010-09-14 Intelleflex Corporation RFID sensor tag with manual modes and functions
US7909842B2 (en) 2006-06-15 2011-03-22 Abbott Diabetes Care Inc. Lancing devices having depth adjustment assembly
US20080177149A1 (en) 2006-06-16 2008-07-24 Stefan Weinert System and method for collecting patient information from which diabetes therapy may be determined
US20080046038A1 (en) 2006-06-26 2008-02-21 Hill Gerard J Local communications network for distributed sensing and therapy in biomedical applications
US20080004601A1 (en) 2006-06-28 2008-01-03 Abbott Diabetes Care, Inc. Analyte Monitoring and Therapy Management System and Methods Therefor
US20090105560A1 (en) 2006-06-28 2009-04-23 David Solomon Lifestyle and eating advisor based on physiological and biological rhythm monitoring
GB0612834D0 (en) 2006-06-28 2006-08-09 Glysure Ltd Sensor calibration
WO2008001366A2 (en) 2006-06-28 2008-01-03 Endo-Rhythm Ltd. Lifestyle and eating advisor based on physiological and biological rhythm monitoring
US20090105571A1 (en) 2006-06-30 2009-04-23 Abbott Diabetes Care, Inc. Method and System for Providing Data Communication in Data Management Systems
US9119582B2 (en) 2006-06-30 2015-09-01 Abbott Diabetes Care, Inc. Integrated analyte sensor and infusion device and methods therefor
US7680469B2 (en) 2006-07-06 2010-03-16 Hewlett-Packard Development Company, L.P. Electronic device power management system and method
DK2365452T3 (da) 2006-07-07 2020-11-16 Hoffmann La Roche Væskeindgivelsesanordning og fremgangsmåder til drift deraf
US20080011971A1 (en) 2006-07-11 2008-01-17 Jiffy-Tite Co., Inc. Quick opening drain plug assembly
US7828916B2 (en) 2006-07-20 2010-11-09 Abbott Cardiovascular Systems Inc. Methods of crimping expandable medical devices
US8114023B2 (en) 2006-07-28 2012-02-14 Legacy Emanuel Hospital & Health Center Analyte sensing and response system
US7866026B1 (en) 2006-08-01 2011-01-11 Abbott Diabetes Care Inc. Method for making calibration-adjusted sensors
MX2009000876A (es) 2006-08-02 2009-02-04 Unomedical As Dispositivo de insercion.
US8932216B2 (en) 2006-08-07 2015-01-13 Abbott Diabetes Care Inc. Method and system for providing data management in integrated analyte monitoring and infusion system
US7914460B2 (en) 2006-08-15 2011-03-29 University Of Florida Research Foundation, Inc. Condensate glucose analyzer
GB0616331D0 (en) 2006-08-16 2006-09-27 Innovision Res & Tech Plc Near Field RF Communicators And Near Field Communications Enabled Devices
US20090256572A1 (en) 2008-04-14 2009-10-15 Mcdowell Andrew F Tuning Low-Inductance Coils at Low Frequencies
US7736338B2 (en) 2006-08-23 2010-06-15 Medtronic Minimed, Inc. Infusion medium delivery system, device and method with needle inserter and needle inserter device and method
DK2054109T3 (en) † 2006-08-24 2018-03-19 Hoffmann La Roche INTRODUCTION DEVICE FOR INTRODUCTION HEADS, ESPECIALLY FOR INFUSION KITS
US8758238B2 (en) 2006-08-31 2014-06-24 Health Hero Network, Inc. Health related location awareness
US7769456B2 (en) 2006-09-01 2010-08-03 Cardiac Pacemakers, Inc. Frequency-agile system for telemetry with implantable device
US20080058626A1 (en) 2006-09-05 2008-03-06 Shinichi Miyata Analytical meter with display-based tutorial module
US20080058678A1 (en) 2006-09-05 2008-03-06 Shinichi Miyata Kit for the determination of an analyte in a bodily fluid sample that includes a meter with a display-based tutorial module
US9056165B2 (en) 2006-09-06 2015-06-16 Medtronic Minimed, Inc. Intelligent therapy recommendation algorithm and method of using the same
US20080071328A1 (en) 2006-09-06 2008-03-20 Medtronic, Inc. Initiating medical system communications
US8234706B2 (en) 2006-09-08 2012-07-31 Microsoft Corporation Enabling access to aggregated software security information
US8381180B2 (en) 2006-09-08 2013-02-19 Sap Ag Visually exposing data services to analysts
US7696941B2 (en) 2006-09-11 2010-04-13 Elster Electricity, Llc Printed circuit notch antenna
DE102006043484B4 (de) 2006-09-15 2019-11-28 Infineon Technologies Ag Fuse-Struktur und Verfahren zum Herstellen derselben
US7779332B2 (en) 2006-09-25 2010-08-17 Alfred E. Mann Foundation For Scientific Research Rotationally invariant non-coherent burst coding
JP4586788B2 (ja) 2006-10-03 2010-11-24 富士ゼロックス株式会社 被搬送物搬送装置及び画像形成装置
US8275438B2 (en) 2006-10-04 2012-09-25 Dexcom, Inc. Analyte sensor
US8449464B2 (en) 2006-10-04 2013-05-28 Dexcom, Inc. Analyte sensor
US8447376B2 (en) 2006-10-04 2013-05-21 Dexcom, Inc. Analyte sensor
US8298142B2 (en) 2006-10-04 2012-10-30 Dexcom, Inc. Analyte sensor
US8478377B2 (en) 2006-10-04 2013-07-02 Dexcom, Inc. Analyte sensor
US7831287B2 (en) 2006-10-04 2010-11-09 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8562528B2 (en) 2006-10-04 2013-10-22 Dexcom, Inc. Analyte sensor
US8255026B1 (en) 2006-10-12 2012-08-28 Masimo Corporation, Inc. Patient monitor capable of monitoring the quality of attached probes and accessories
US20080092638A1 (en) 2006-10-19 2008-04-24 Bayer Healthcare Llc Wireless analyte monitoring system
US8126728B2 (en) 2006-10-24 2012-02-28 Medapps, Inc. Systems and methods for processing and transmittal of medical data through an intermediary device
EP2106238A4 (en) 2006-10-26 2011-03-09 Abbott Diabetes Care Inc METHOD, SYSTEM AND COMPUTER PROGRAM PRODUCT FOR REAL-TIME DETECTION OF SENSITIVITY DECLINE IN PRODUCT DETECTORS
US20080119710A1 (en) 2006-10-31 2008-05-22 Abbott Diabetes Care, Inc. Medical devices and methods of using the same
US7822557B2 (en) 2006-10-31 2010-10-26 Abbott Diabetes Care Inc. Analyte sensors and methods
EP1918837A1 (en) 2006-10-31 2008-05-07 F. Hoffmann-La Roche AG Method for processing a chronological sequence of measurements of a time dependent parameter
US8439837B2 (en) 2006-10-31 2013-05-14 Lifescan, Inc. Systems and methods for detecting hypoglycemic events having a reduced incidence of false alarms
US8158081B2 (en) 2006-10-31 2012-04-17 Abbott Diabetes Care Inc. Analyte monitoring devices
US20080119705A1 (en) 2006-11-17 2008-05-22 Medtronic Minimed, Inc. Systems and Methods for Diabetes Management Using Consumer Electronic Devices
FI20065735A0 (fi) 2006-11-20 2006-11-20 Salla Koski Mittaus-, seuranta- ja hoitojärjestelmä sekä järjestelmään kuuluvia laitteita
CA2670265A1 (en) 2006-11-23 2008-05-29 Lifescan Scotland Limited Blood glucose meter capable of wireless communication
FR2909001B1 (fr) 2006-11-24 2009-12-18 Bernard Perriere Dispositif d'injection et de prelevement miniaturise et automatique a usage medical.
ES2690306T3 (es) 2006-11-28 2018-11-20 F. Hoffmann-La Roche Ag Un dispositivo de inserción y método para insertar un elemento insertable de manera subcutánea en un cuerpo
US8079955B2 (en) 2006-11-28 2011-12-20 Isense Corporation Method and apparatus for managing glucose control
US20080133059A1 (en) 2006-12-05 2008-06-05 Bayer Healthcare Llc Table-driven test sequence
US20080139910A1 (en) 2006-12-06 2008-06-12 Metronic Minimed, Inc. Analyte sensor and method of using the same
US20080139903A1 (en) 2006-12-08 2008-06-12 Isense Corporation Method and apparatus for insertion of a sensor using an introducer
US8548554B2 (en) 2006-12-08 2013-10-01 Fraunhofer-Gesellschaft Zur Forderung Der Angewandten Forschung E.V. Dry electrode cap for electro-encephalography
KR100833511B1 (ko) 2006-12-08 2008-05-29 한국전자통신연구원 휘발성 메모리를 구비한 패시브 태그
WO2008071218A1 (en) 2006-12-14 2008-06-19 Egomedical Swiss Ag Monitoring device
US8120493B2 (en) 2006-12-20 2012-02-21 Intel Corporation Direct communication in antenna devices
US20080154286A1 (en) 2006-12-21 2008-06-26 Ryan Abbott Systems and Methods for Treating Septal Defects with Capture Devices and Other Devices
US20080154513A1 (en) 2006-12-21 2008-06-26 University Of Virginia Patent Foundation Systems, Methods and Computer Program Codes for Recognition of Patterns of Hyperglycemia and Hypoglycemia, Increased Glucose Variability, and Ineffective Self-Monitoring in Diabetes
DK3632488T3 (da) 2006-12-22 2023-06-06 Hoffmann La Roche Anordning til vedvarende indgivelse af en terapeutisk væske
US7802467B2 (en) 2006-12-22 2010-09-28 Abbott Diabetes Care Inc. Analyte sensors and methods of use
US7946985B2 (en) 2006-12-29 2011-05-24 Medtronic Minimed, Inc. Method and system for providing sensor redundancy
US20080161666A1 (en) 2006-12-29 2008-07-03 Abbott Diabetes Care, Inc. Analyte devices and methods
MX2009007613A (es) 2007-01-15 2009-09-22 Deka Products Lp Dispositivo y metodo para manejo de alimentos.
US8098160B2 (en) 2007-01-22 2012-01-17 Cisco Technology, Inc. Method and system for remotely provisioning and/or configuring a device
US7734323B2 (en) 2007-01-24 2010-06-08 Smiths Medical Asd, Inc. Correction factor testing using frequent blood glucose input
US7742747B2 (en) 2007-01-25 2010-06-22 Icera Canada ULC Automatic IIP2 calibration architecture
US10154804B2 (en) 2007-01-31 2018-12-18 Medtronic Minimed, Inc. Model predictive method and system for controlling and supervising insulin infusion
US8808515B2 (en) 2007-01-31 2014-08-19 Abbott Diabetes Care Inc. Heterocyclic nitrogen containing polymers coated analyte monitoring device and methods of use
US9597019B2 (en) 2007-02-09 2017-03-21 Lifescan, Inc. Method of ensuring date and time on a test meter is accurate
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8732188B2 (en) 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
WO2008105768A1 (en) 2007-03-01 2008-09-04 Dexcom, Inc. Analyte sensor
US7751864B2 (en) 2007-03-01 2010-07-06 Roche Diagnostics Operations, Inc. System and method for operating an electrochemical analyte sensor
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
WO2008109739A1 (en) 2007-03-07 2008-09-12 Echo Therapeutics, Inc. Transdermal analyte monitoring systems and methods for analyte detection
US20090093687A1 (en) 2007-03-08 2009-04-09 Telfort Valery G Systems and methods for determining a physiological condition using an acoustic monitor
ATE485858T1 (de) † 2007-03-14 2010-11-15 Hoffmann La Roche Insertionskopf für medizinische oder pharmazeutische anwendungen
CN104069567A (zh) 2007-03-19 2014-10-01 茵苏莱恩医药有限公司 药物输送设备
WO2008115409A1 (en) 2007-03-19 2008-09-25 Bayer Healthcare Llc Continuous analyte monitoring assembly and method of forming the same
EP1972267A1 (de) 2007-03-20 2008-09-24 Roche Diagnostics GmbH System zur in-vivo Messung einer Analytkonzentration
EP1972275B1 (de) 2007-03-20 2015-10-28 Roche Diagnostics GmbH System zur in-vivo Messung einer Analytkonzentration
US7659823B1 (en) 2007-03-20 2010-02-09 At&T Intellectual Property Ii, L.P. Tracking variable conditions using radio frequency identification
US8758245B2 (en) 2007-03-20 2014-06-24 Lifescan, Inc. Systems and methods for pattern recognition in diabetes management
EP1972270B1 (en) 2007-03-23 2010-11-03 Roche Diagnostics GmbH Method and glucose monitoring system for monitoring individual metabolic response
US8469986B2 (en) 2007-03-30 2013-06-25 Stat Medical Devices, Inc. Lancet device with combined trigger and cocking mechanism and method
US20080243051A1 (en) 2007-03-30 2008-10-02 Animas Corporation Torsion bar-based cannula insertion device
US20080249383A1 (en) 2007-04-04 2008-10-09 Isense Corporation Analyte sensing device having one or more sensing electrodes
US9029157B2 (en) 2007-04-12 2015-05-12 Nipro Diagnostics, Inc. Error detection and rejection for a diagnostic testing system
CA2683959C (en) 2007-04-14 2017-08-29 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in medical communication system
CA2683721C (en) 2007-04-14 2017-05-23 Abbott Diabetes Care Inc. Method and apparatus for providing dynamic multi-stage signal amplification in a medical device
EP2146623B1 (en) 2007-04-14 2014-01-08 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in medical communication system
US8140142B2 (en) 2007-04-14 2012-03-20 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in medical communication system
EP3741291A1 (en) 2007-04-14 2020-11-25 Abbott Diabetes Care, Inc. Method and apparatus for providing data processing and control in medical communication system
WO2008130898A1 (en) 2007-04-14 2008-10-30 Abbott Diabetes Care, Inc. Method and apparatus for providing data processing and control in medical communication system
JP2010524554A (ja) 2007-04-19 2010-07-22 シー・ジー・エム・３・リミテツド 血液アナライトレベルを監視および制御するための装置システムおよび方法
US20080262300A1 (en) 2007-04-20 2008-10-23 Usgi Medical, Inc. Endoscopic system with disposable sheath
US9554721B1 (en) 2007-04-23 2017-01-31 Neurowave Systems Inc. Seizure detector, brain dysfunction monitor and method
US20080269714A1 (en) 2007-04-25 2008-10-30 Medtronic Minimed, Inc. Closed loop/semi-closed loop therapy modification system
US20080269673A1 (en) 2007-04-27 2008-10-30 Animas Corporation Cellular-Enabled Medical Monitoring and Infusion System
AU2008245537A1 (en) 2007-04-27 2008-11-06 Abbott Diabetes Care, Inc. Test strip identification using conductive patterns
JP5277242B2 (ja) 2007-04-30 2013-08-28 メドトロニック ミニメド インコーポレイテッド 注入媒質送達システム用の針挿入および流体流通接続
US8323250B2 (en) 2007-04-30 2012-12-04 Medtronic Minimed, Inc. Adhesive patch systems and methods
US8692655B2 (en) 2007-05-07 2014-04-08 Bloomberg Finance L.P. Dynamically programmable RFID transponder
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US20080281179A1 (en) 2007-05-08 2008-11-13 Abbott Diabetes Care, Inc. Analyte monitoring system and methods
CA2686641C (en) 2007-05-08 2018-07-10 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US10002233B2 (en) 2007-05-14 2018-06-19 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8444560B2 (en) 2007-05-14 2013-05-21 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8260558B2 (en) 2007-05-14 2012-09-04 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US20080312845A1 (en) 2007-05-14 2008-12-18 Abbott Diabetes Care, Inc. Method and apparatus for providing data processing and control in a medical communication system
EP2156684A4 (en) 2007-05-14 2012-10-24 Abbott Diabetes Care Inc METHOD AND DEVICE FOR PROVIDING DATA PROCESSING AND CONTROL IN A MEDICAL COMMUNICATION SYSTEM
US8103471B2 (en) 2007-05-14 2012-01-24 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US7996158B2 (en) 2007-05-14 2011-08-09 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US9125548B2 (en) 2007-05-14 2015-09-08 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8600681B2 (en) 2007-05-14 2013-12-03 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8239166B2 (en) 2007-05-14 2012-08-07 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8560038B2 (en) 2007-05-14 2013-10-15 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US20080287755A1 (en) 2007-05-17 2008-11-20 Isense Corporation Method and apparatus for trend alert calculation and display
WO2008147921A1 (en) 2007-05-22 2008-12-04 Imaging Biometrics Multiparameter perfusion imaging with leakage correction
US20080294024A1 (en) 2007-05-24 2008-11-27 Cosentino Daniel L Glucose meter system and monitor
DE102007026083A1 (de) 2007-05-25 2008-11-27 Haselmeier S.A.R.L. Injektionsgerät
WO2008150917A1 (en) 2007-05-31 2008-12-11 Abbott Diabetes Care, Inc. Insertion devices and methods
US20080300572A1 (en) 2007-06-01 2008-12-04 Medtronic Minimed, Inc. Wireless monitor for a personal medical device system
US8072310B1 (en) 2007-06-05 2011-12-06 Pulsed Indigo Inc. System for detecting and measuring parameters of passive transponders
US20080306434A1 (en) 2007-06-08 2008-12-11 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US20080312518A1 (en) 2007-06-14 2008-12-18 Arkal Medical, Inc On-demand analyte monitor and method of use
CN107411754A (zh) 2007-06-15 2017-12-01 霍夫曼-拉罗奇有限公司 在人体上测量的参数的可视化
CA2692038A1 (en) 2007-06-15 2008-12-24 Lifescan, Inc. Flexible cannula or medical device conduit
EP2155296B1 (en) 2007-06-20 2019-08-28 Unomedical A/S Cannula insertion device with automatic needle retraction comprising only one spring
JP5680960B2 (ja) 2007-06-21 2015-03-04 アボット ダイアベティス ケア インコーポレイテッドＡｂｂｏｔｔ Ｄｉａｂｅｔｅｓ Ｃａｒｅ Ｉｎｃ． 健康管理装置および方法
WO2008157821A1 (en) 2007-06-21 2008-12-24 Abbott Diabetes Care, Inc. Health monitor
US20080319327A1 (en) 2007-06-25 2008-12-25 Triage Wireless, Inc. Body-worn sensor featuring a low-power processor and multi-sensor array for measuring blood pressure
US8002752B2 (en) * 2007-06-25 2011-08-23 Medingo, Ltd. Protector apparatus
US8641618B2 (en) 2007-06-27 2014-02-04 Abbott Diabetes Care Inc. Method and structure for securing a monitoring device element
EP2171630A1 (en) 2007-06-27 2010-04-07 F. Hoffmann-Roche AG System and method for developing patient specific therapies based on modeling of patient physiology
US20090005729A1 (en) 2007-06-27 2009-01-01 Animas Corporation Medical infusion pumps
US20090006133A1 (en) 2007-06-27 2009-01-01 Roche Diagnostics Operations, Inc. Patient information input interface for a therapy system
WO2009005957A1 (en) 2007-06-29 2009-01-08 Roche Diagnostics Gmbh Apparatus and method for remotely controlling an ambulatory medical device
US8160900B2 (en) 2007-06-29 2012-04-17 Abbott Diabetes Care Inc. Analyte monitoring and management device and method to analyze the frequency of user interaction with the device
DE102007031714A1 (de) 2007-07-06 2009-01-08 Lts Lohmann Therapie-Systeme Ag Einweginjektor mit mindestens einem Druckstab und einer Verschlusskappe
ATE499128T1 (de) 2007-07-10 2011-03-15 Unomedical As Inserter mit zwei federn
US8246588B2 (en) 2007-07-18 2012-08-21 Unomedical A/S Insertion device with pivoting action
EP2167173A1 (en) * 2007-07-18 2010-03-31 Unomedical A/S Inserter device with controlled acceleration
US8491565B2 (en) 2007-07-20 2013-07-23 Medingo Ltd. Collapsible reservoir for use with a delivery device
CA2698038A1 (en) 2007-07-26 2009-01-29 Entra Pharmaceuticals Inc. Systems and methods for delivering drugs
US20090036760A1 (en) 2007-07-31 2009-02-05 Abbott Diabetes Care, Inc. Method and apparatus for providing data processing and control in a medical communication system
CA2694931C (en) 2007-07-31 2014-04-29 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US7768386B2 (en) 2007-07-31 2010-08-03 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8834366B2 (en) 2007-07-31 2014-09-16 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor calibration
US8147446B2 (en) 2007-08-01 2012-04-03 Medingo Ltd. Detachable portable infusion device
WO2009016638A1 (en) 2007-08-01 2009-02-05 Medingo Ltd. Device for facilitating infusion of therapeutic fluids and sensing of bodily analytes
US7731658B2 (en) 2007-08-16 2010-06-08 Cardiac Pacemakers, Inc. Glycemic control monitoring using implantable medical device
US8926509B2 (en) 2007-08-24 2015-01-06 Hmicro, Inc. Wireless physiological sensor patches and systems
US9968742B2 (en) 2007-08-29 2018-05-15 Medtronic Minimed, Inc. Combined sensor and infusion set using separated sites
US20090063402A1 (en) 2007-08-31 2009-03-05 Abbott Diabetes Care, Inc. Method and System for Providing Medication Level Determination
US9848058B2 (en) 2007-08-31 2017-12-19 Cardiac Pacemakers, Inc. Medical data transport over wireless life critical network employing dynamic communication link mapping
US8515547B2 (en) 2007-08-31 2013-08-20 Cardiac Pacemakers, Inc. Wireless patient communicator for use in a life critical network
US8303545B2 (en) 2007-09-07 2012-11-06 Stat Medical Devices, Inc. Infusion device and method of using and making the same
EP2200677A1 (en) 2007-09-17 2010-06-30 ICU Medical, Inc. Insertion devices for infusion devices
HRP20150979T1 (hr) 2007-09-24 2015-11-20 Bayer Healthcare Llc Više-podruäśni i ispitni senzori za potencijal, postupci i sustavi
DE102007047351A1 (de) 2007-10-02 2009-04-09 B. Braun Melsungen Ag System und Verfahren zur Überwachung und Regelung von Blutglukosewerten
US20090085768A1 (en) 2007-10-02 2009-04-02 Medtronic Minimed, Inc. Glucose sensor transceiver
JP5587782B2 (ja) 2007-10-10 2014-09-10 オプテイスカン・バイオメデイカル・コーポレーシヨン グルコースのモニターおよび調節のための流体成分分析システムおよび方法
DE102007049446A1 (de) 2007-10-16 2009-04-23 Cequr Aps Katheter-Einführeinrichtung
US8216138B1 (en) 2007-10-23 2012-07-10 Abbott Diabetes Care Inc. Correlation of alternative site blood and interstitial fluid glucose concentrations to venous glucose concentration
US8409093B2 (en) 2007-10-23 2013-04-02 Abbott Diabetes Care Inc. Assessing measures of glycemic variability
US8377031B2 (en) 2007-10-23 2013-02-19 Abbott Diabetes Care Inc. Closed loop control system with safety parameters and methods
US8000918B2 (en) 2007-10-23 2011-08-16 Edwards Lifesciences Corporation Monitoring and compensating for temperature-related error in an electrochemical sensor
US8417312B2 (en) 2007-10-25 2013-04-09 Dexcom, Inc. Systems and methods for processing sensor data
US7783442B2 (en) 2007-10-31 2010-08-24 Medtronic Minimed, Inc. System and methods for calibrating physiological characteristic sensors
CA2703732A1 (en) 2007-11-07 2009-05-14 Ovalis, Inc. Systems, devices and methods for achieving transverse orientation in the treatment of septal defects
EP2060289A1 (en) 2007-11-13 2009-05-20 F.Hoffmann-La Roche Ag Administration device comprising indication unit and method for setting a dose
EP2060284A1 (en) 2007-11-13 2009-05-20 F.Hoffmann-La Roche Ag Medical injection device having data input means and a pivotable display
DK2224977T3 (en) 2007-11-21 2017-08-14 Hoffmann La Roche ANALYSIS MONITORING AND FLUID DISTRIBUTION SYSTEM
US8098201B2 (en) 2007-11-29 2012-01-17 Electronics & Telecommunications Research Institute Radio frequency identification tag and radio frequency identification tag antenna
WO2009068661A1 (en) 2007-11-29 2009-06-04 Universiteit Maastricht Device for thoracostomy
US8078592B2 (en) 2007-12-07 2011-12-13 Roche Diagnostics Operations, Inc. System and method for database integrity checking
US8103241B2 (en) 2007-12-07 2012-01-24 Roche Diagnostics Operations, Inc. Method and system for wireless device communication
US8290559B2 (en) 2007-12-17 2012-10-16 Dexcom, Inc. Systems and methods for processing sensor data
US20090164190A1 (en) 2007-12-19 2009-06-25 Abbott Diabetes Care, Inc. Physiological condition simulation device and method
US20090164239A1 (en) 2007-12-19 2009-06-25 Abbott Diabetes Care, Inc. Dynamic Display Of Glucose Information
US20090163855A1 (en) 2007-12-24 2009-06-25 Medtronic Minimed, Inc. Infusion system with adaptive user interface
JP2011510402A (ja) 2008-01-15 2011-03-31 コーニング ケーブル システムズ エルエルシー 複雑システムの物理的構成を自動的に検出及び／または指示するためのｒｆｉｄシステム及び方法
US8721603B2 (en) 2008-01-15 2014-05-13 West Pharmaceutical Services, Inc. Syringe with co-molded hub and cannula
DE102008008072A1 (de) 2008-01-29 2009-07-30 Balluff Gmbh Sensor
WO2009097450A1 (en) 2008-01-30 2009-08-06 Dexcom. Inc. Continuous cardiac marker sensor system
CA2711772A1 (en) 2008-02-08 2009-08-13 Unomedical A/S Inserter assembly
WO2009098291A1 (en) 2008-02-08 2009-08-13 Unomedical A/S Assembly comprising inserter, cannula part and base part
EP2090996A1 (en) 2008-02-16 2009-08-19 Roche Diagnostics GmbH Medical device
AU2009216703A1 (en) * 2008-02-20 2009-08-27 Unomedical A/S Insertion device with horizontally moving part
JP5091881B2 (ja) 2008-02-20 2012-12-05 カルソニックカンセイ株式会社 衝突検知装置
CA2715624A1 (en) 2008-02-20 2009-08-27 Dexcom, Inc. Continuous medicament sensor system for in vivo use
CA2715628A1 (en) 2008-02-21 2009-08-27 Dexcom, Inc. Systems and methods for processing, transmitting and displaying sensor data
US8122783B2 (en) 2008-02-22 2012-02-28 Sauer-Danfoss Inc. Joystick and method of manufacturing the same
WO2009107135A2 (en) 2008-02-27 2009-09-03 Mon4D Ltd. Device, system and method for modular analyte monitoring
US8317699B2 (en) 2008-02-29 2012-11-27 Roche Diagnostics Operations, Inc. Device and method for assessing blood glucose control
BRPI0909208A2 (pt) 2008-03-10 2015-10-27 Koninkl Philips Electronics Nv sistema de monitoração cardíaca sem fio
US20110022411A1 (en) 2008-03-19 2011-01-27 Telefonaktiebolaget Lm Ericsson (Publ) NFC Communications for Implanted Medical Data Acquisition Devices
US20090240121A1 (en) 2008-03-21 2009-09-24 Nova Biomedical Corporation Intravascular sensor and insertion set combination
US8396528B2 (en) 2008-03-25 2013-03-12 Dexcom, Inc. Analyte sensor
US20090242399A1 (en) 2008-03-25 2009-10-01 Dexcom, Inc. Analyte sensor
US8583204B2 (en) 2008-03-28 2013-11-12 Dexcom, Inc. Polymer membranes for continuous analyte sensors
EP2257794B1 (en) 2008-03-28 2018-05-09 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8682408B2 (en) 2008-03-28 2014-03-25 Dexcom, Inc. Polymer membranes for continuous analyte sensors
WO2009124095A1 (en) 2008-03-31 2009-10-08 Abbott Diabetes Care Inc. Shallow implantable analyte sensor with rapid physiological response
ES2719305T3 (es) 2008-04-04 2019-07-09 Hygieia Inc Sistema para optimizar un régimen de dosificación de insulina para un paciente
EP2262543B1 (en) 2008-04-10 2015-07-08 Abbott Diabetes Care Inc. Method and system for sterilizing an analyte sensor
US20110031986A1 (en) 2008-04-11 2011-02-10 Navakanta Bhat Sub-Threshold Capfet Sensor for Sensing Analyte, A Method and System Thereof
US9924898B2 (en) 2008-04-15 2018-03-27 Becton, Dickinson And Company Flash activated passive shielding needle assembly
US7783342B2 (en) 2008-04-21 2010-08-24 International Business Machines Corporation System and method for inferring disease similarity by shape matching of ECG time series
US20090267765A1 (en) 2008-04-29 2009-10-29 Jack Greene Rfid to prevent reprocessing
USD618337S1 (en) 2008-05-02 2010-06-22 KCI Licensing, Inc, Reduced pressure treatment apparatus
US7938797B2 (en) 2008-05-05 2011-05-10 Asante Solutions, Inc. Infusion pump system
US8102021B2 (en) 2008-05-12 2012-01-24 Sychip Inc. RF devices
AU2009246442B2 (en) 2008-05-14 2015-02-12 Heartmiles, Llc. Physical activity monitor and data collection unit
US8610577B2 (en) 2008-05-20 2013-12-17 Deka Products Limited Partnership RFID system
US9295786B2 (en) * 2008-05-28 2016-03-29 Medtronic Minimed, Inc. Needle protective device for subcutaneous sensors
US20090294277A1 (en) 2008-05-30 2009-12-03 Abbott Diabetes Care, Inc. Method and system for producing thin film biosensors
US8924159B2 (en) 2008-05-30 2014-12-30 Abbott Diabetes Care Inc. Method and apparatus for providing glycemic control
US8394637B2 (en) 2008-06-02 2013-03-12 Roche Diagnostics Operations, Inc. Handheld analyzer for testing a sample
US8117481B2 (en) 2008-06-06 2012-02-14 Roche Diagnostics International Ag Apparatus and method for processing wirelessly communicated information within an electronic device
US8132037B2 (en) 2008-06-06 2012-03-06 Roche Diagnostics International Ag Apparatus and method for processing wirelessly communicated data and clock information within an electronic device
CN101621714B (zh) 2008-06-30 2013-06-12 华为技术有限公司 节点、数据处理系统和数据处理方法
EP2293831A1 (en) 2008-07-07 2011-03-16 Unomedical A/S Inserter for transcutaneous device
WO2010005806A2 (en) 2008-07-09 2010-01-14 Cardiac Pacemakers, Inc. Event-based battery monitor for implantable devices
US8876755B2 (en) 2008-07-14 2014-11-04 Abbott Diabetes Care Inc. Closed loop control system interface and methods
US20100025238A1 (en) 2008-07-31 2010-02-04 Medtronic Minimed, Inc. Analyte sensor apparatuses having improved electrode configurations and methods for making and using them
US20100030052A1 (en) 2008-07-31 2010-02-04 Bommakanti Balasubrahmanya S Analyte sensors comprising plasticizers
US8111042B2 (en) 2008-08-05 2012-02-07 Broadcom Corporation Integrated wireless resonant power charging and communication channel
JP5125876B2 (ja) 2008-08-20 2013-01-23 ニプロ株式会社 挿入装置
US8432070B2 (en) 2008-08-25 2013-04-30 Qualcomm Incorporated Passive receivers for wireless power transmission
US8094009B2 (en) 2008-08-27 2012-01-10 The Invention Science Fund I, Llc Health-related signaling via wearable items
US8734422B2 (en) 2008-08-31 2014-05-27 Abbott Diabetes Care Inc. Closed loop control with improved alarm functions
US9943644B2 (en) 2008-08-31 2018-04-17 Abbott Diabetes Care Inc. Closed loop control with reference measurement and methods thereof
US20100057040A1 (en) 2008-08-31 2010-03-04 Abbott Diabetes Care, Inc. Robust Closed Loop Control And Methods
US8102154B2 (en) 2008-09-04 2012-01-24 Medtronic Minimed, Inc. Energy source isolation and protection circuit for an electronic device
US8636884B2 (en) 2008-09-15 2014-01-28 Abbott Diabetes Care Inc. Cationic polymer based wired enzyme formulations for use in analyte sensors
US20100095229A1 (en) 2008-09-18 2010-04-15 Abbott Diabetes Care, Inc. Graphical user interface for glucose monitoring system
WO2010033724A2 (en) 2008-09-19 2010-03-25 Dexcom, Inc. Particle-containing membrane and particulate electrode for analyte sensors
US8983568B2 (en) 2008-09-30 2015-03-17 Abbott Diabetes Care Inc. Analyte sensors comprising leveling agents
US8986208B2 (en) 2008-09-30 2015-03-24 Abbott Diabetes Care Inc. Analyte sensor sensitivity attenuation mitigation
KR20110081250A (ko) 2008-10-02 2011-07-13 레이덴 에너지 인코오포레이티드 배터리용 전자 전류 차단 장치
US8287487B2 (en) 2008-10-15 2012-10-16 Asante Solutions, Inc. Infusion pump system and methods
DE102008053216A1 (de) 2008-10-25 2010-05-06 IHP GmbH - Innovations for High Performance Institut für innovative Mikroelektronik Anordnung für einen transdermalen Sensor zur Erfassung und drahtlosen Übertragung von Messgrößen des Unterhautfettgewebes
EP2345893B1 (en) 2008-11-04 2016-05-04 Panasonic Healthcare Holdings Co., Ltd. Measurement device, measurement method, and program
US20100331644A1 (en) 2008-11-07 2010-12-30 Dexcom, Inc. Housing for an intravascular sensor
US9326707B2 (en) 2008-11-10 2016-05-03 Abbott Diabetes Care Inc. Alarm characterization for analyte monitoring devices and systems
CA2753650A1 (en) 2008-11-26 2010-06-03 University Of Virginia Patent Foundation Method, system, and computer program product for tracking of blood glucose variability in diabetes
US8098161B2 (en) 2008-12-01 2012-01-17 Raytheon Company Radio frequency identification inlay with improved readability
US20100145377A1 (en) * 2008-12-04 2010-06-10 Venture Corporation Limited Lancing Device For Minimizing Pain
JP5121940B2 (ja) 2008-12-09 2013-01-16 パナソニック株式会社 減圧機構、穿刺装置、血液分析装置及びセンサ装着機構
US8150516B2 (en) 2008-12-11 2012-04-03 Pacesetter, Inc. Systems and methods for operating an implantable device for medical procedures
WO2010080584A1 (en) 2008-12-18 2010-07-15 Facet Technologies, Llc Lancing device and lancet
US8028837B2 (en) 2008-12-18 2011-10-04 Kimberly-Clark Worldwide, Inc. Break-open package with shaped die cut for storing and dispensing substrates
US20100169035A1 (en) 2008-12-29 2010-07-01 Medtronic Minimed, Inc. Methods and systems for observing sensor parameters
US20100168547A1 (en) 2008-12-29 2010-07-01 David Kendricks Universal din leadwire system for use with ekg and ecg patient monitoring and event recording instruments
US9320470B2 (en) 2008-12-31 2016-04-26 Medtronic Minimed, Inc. Method and/or system for sensor artifact filtering
US8974439B2 (en) 2009-01-02 2015-03-10 Asante Solutions, Inc. Infusion pump system and methods
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US8560082B2 (en) 2009-01-30 2013-10-15 Abbott Diabetes Care Inc. Computerized determination of insulin pump therapy parameters using real time and retrospective data processing
US20100198034A1 (en) * 2009-02-03 2010-08-05 Abbott Diabetes Care Inc. Compact On-Body Physiological Monitoring Devices and Methods Thereof
US20100198142A1 (en) 2009-02-04 2010-08-05 Abbott Diabetes Care Inc. Multi-Function Analyte Test Device and Methods Therefor
US20100198033A1 (en) 2009-02-05 2010-08-05 Peter Krulevitch Flexible indwelling biosensor, flexible indwelling biosensor insertion device, and related methods
US8394246B2 (en) 2009-02-23 2013-03-12 Roche Diagnostics Operations, Inc. System and method for the electrochemical measurement of an analyte employing a remote sensor
CN201370857Y (zh) 2009-02-25 2009-12-30 中国人民解放军总医院 微创治疗穿刺针
EP2400886A4 (en) 2009-02-26 2014-07-02 Abbott Diabetes Care Inc IMPROVED ANALYTICAL SENSORS AND METHOD FOR THEIR MANUFACTURE AND USE
US20100213057A1 (en) 2009-02-26 2010-08-26 Benjamin Feldman Self-Powered Analyte Sensor
WO2010111660A1 (en) 2009-03-27 2010-09-30 Dexcom, Inc. Methods and systems for promoting glucose management
EP2272553A1 (en) 2009-06-29 2011-01-12 Unomedical A/S Inserter Assembly
US20100274515A1 (en) 2009-04-28 2010-10-28 Abbott Diabetes Care Inc. Dynamic Analyte Sensor Calibration Based On Sensor Stability Profile
US9226701B2 (en) 2009-04-28 2016-01-05 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
US8483967B2 (en) 2009-04-29 2013-07-09 Abbott Diabetes Care Inc. Method and system for providing real time analyte sensor calibration with retrospective backfill
EP3925533B1 (en) 2009-04-30 2024-04-10 DexCom, Inc. Performance reports associated with continuous sensor data from multiple analysis time periods
MY153913A (en) 2009-05-12 2015-04-15 Janssen Pharmaceuticals Inc 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
DE102009022772A1 (de) 2009-05-21 2010-11-25 Organobalance Gmbh Mikroorganismus zur Expression eines humanen Membranproteins
EP2432393A2 (en) 2009-05-22 2012-03-28 Abbott Diabetes Care, Inc. Method and system for reducing false hypoglycemia alarm occurrence
EP2438527B1 (en) 2009-06-04 2018-05-02 Abbott Diabetes Care, Inc. Method and system for updating a medical device
US8124452B2 (en) 2009-06-14 2012-02-28 Terepac Corporation Processes and structures for IC fabrication
US9218453B2 (en) 2009-06-29 2015-12-22 Roche Diabetes Care, Inc. Blood glucose management and interface systems and methods
US10376213B2 (en) 2009-06-30 2019-08-13 Waveform Technologies, Inc. System, method and apparatus for sensor insertion
US8613892B2 (en) 2009-06-30 2013-12-24 Abbott Diabetes Care Inc. Analyte meter with a moveable head and methods of using the same
US20100331643A1 (en) 2009-06-30 2010-12-30 Abbott Diabetes Care Inc. Extruded Analyte Sensors and Methods of Using Same
US8437827B2 (en) 2009-06-30 2013-05-07 Abbott Diabetes Care Inc. Extruded analyte sensors and methods of using same
US9792408B2 (en) 2009-07-02 2017-10-17 Covidien Lp Method and apparatus to detect transponder tagged objects and to communicate with medical telemetry devices, for example during medical procedures
WO2011003039A2 (en) 2009-07-02 2011-01-06 Dexcom, Inc. Analyte sensors and methods of manufacturing same
US20120165626A1 (en) 2009-07-13 2012-06-28 Irina Finkelshtein V Devices, methods, and kits for determining analyte concentrations
EP3932309A1 (en) 2009-07-23 2022-01-05 Abbott Diabetes Care, Inc. Continuous analyte measurement system
AU2010277755A1 (en) * 2009-07-30 2012-02-02 Unomedical A/S Inserter device with horizontal moving part
RU2012108579A (ru) 2009-08-07 2013-09-20 Уномедикал А/С Доставочное устройство с датчиком и одной или несколькими канюлями
US8868151B2 (en) 2009-08-14 2014-10-21 Bayer Healthcare Llc Electrochemical impedance spectroscopy enabled continuous glucose monitoring sensor system
KR20120081583A (ko) 2009-08-17 2012-07-19 더 리전트 오브 더 유니버시티 오브 캘리포니아 표면 및 표면 아래 생물의학 구조 및 상태의 특성을 위한 분배된 외부 및 내부 무선 센서 시스템
US20110046466A1 (en) 2009-08-19 2011-02-24 Feldman Benjamin J Analyte Sensors Including Nanomaterials and Methods of Using Same
EP2473963A4 (en) 2009-08-31 2014-01-08 Abbott Diabetes Care Inc MEDICAL DEVICES AND METHOD
US20110106126A1 (en) 2009-08-31 2011-05-05 Michael Love Inserter device including rotor subassembly
EP2473098A4 (en) 2009-08-31 2014-04-09 Abbott Diabetes Care Inc ANALYTICAL SIGNAL PROCESSING APPARATUS AND METHOD
WO2011026149A1 (en) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Mounting unit having a sensor and associated circuitry
WO2011026148A1 (en) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Analyte monitoring system and methods for managing power and noise
WO2011026150A1 (en) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Flexible mounting unit and cover for a medical device
ES2950160T3 (es) 2009-08-31 2023-10-05 Abbott Diabetes Care Inc Visualizadores para un dispositivo médico
US8882710B2 (en) † 2009-09-02 2014-11-11 Medtronic Minimed, Inc. Insertion device systems and methods
US8093991B2 (en) 2009-09-16 2012-01-10 Greatbatch Ltd. RFID detection and identification system for implantable medical devices
US8353917B2 (en) 2009-09-25 2013-01-15 Pharmaseq, Inc. Apparatus and method to deliver a microchip
US20110077469A1 (en) 2009-09-27 2011-03-31 Blocker Richard A Systems and methods for utilizing prolonged self monitoring in the analysis of chronic ailment treatments
WO2011041469A1 (en) 2009-09-29 2011-04-07 Abbott Diabetes Care Inc. Method and apparatus for providing notification function in analyte monitoring systems
WO2011041449A1 (en) 2009-09-29 2011-04-07 Abbott Diabetes Care Inc. Sensor inserter having introducer
US20110081726A1 (en) 2009-09-30 2011-04-07 Abbott Diabetes Care Inc. Signal Dropout Detection and/or Processing in Analyte Monitoring Device and Methods
ES2532736T3 (es) 2009-09-30 2015-03-31 Terumo Kabushiki Kaisha Conjunto de aguja de jeringa y dispositivo de jeringa de medicación
WO2011041463A2 (en) 2009-09-30 2011-04-07 Dexcom, Inc. Transcutaneous analyte sensor
WO2011044386A1 (en) 2009-10-07 2011-04-14 Abbott Diabetes Care Inc. Sensor inserter assembly having rotatable trigger
CN102869400A (zh) 2009-10-30 2013-01-09 梅丁格有限公司 用于调节与便携式治疗装置相关的套管的插入深度的系统、方法及装置
US20110123971A1 (en) 2009-11-20 2011-05-26 Medivoce, Inc. Electronic Medical Voice Instruction System
US9949672B2 (en) 2009-12-17 2018-04-24 Ascensia Diabetes Care Holdings Ag Apparatus, systems and methods for determining and displaying pre-event and post-event analyte concentration levels
US8333704B2 (en) 2009-12-18 2012-12-18 Massachusetts Institute Of Technology Handheld force-controlled ultrasound probe
EP2335565A1 (de) 2009-12-18 2011-06-22 Roche Diagnostics GmbH Schutzbehälter für Aufnahme wieder verwendbarer diagnostischer Komponenten
EP3150114B1 (en) 2009-12-23 2022-11-09 Braemar Manufacturing, LLC Monitoring device for attachment to the skin surface
US8474335B2 (en) 2010-01-12 2013-07-02 Veltek Associates, Inc. Microbial air sampler
JP5806236B2 (ja) 2010-01-13 2015-11-10 セブンス センス バイオシステムズ，インコーポレーテッド 流体の急速送達および／また採取
US20110184265A1 (en) 2010-01-22 2011-07-28 Abbott Diabetes Care Inc. Method and Apparatus for Providing Notification in Analyte Monitoring Systems
CA2728831A1 (en) 2010-01-22 2011-07-22 Lifescan, Inc. Diabetes management unit, method, and system
WO2011091179A1 (en) 2010-01-24 2011-07-28 Medtronic, Inc. Method of making a battery including applying a cathode material slurry to a current collector
US8828330B2 (en) * 2010-01-28 2014-09-09 Abbott Diabetes Care Inc. Universal test strip port
US20110184258A1 (en) 2010-01-28 2011-07-28 Abbott Diabetes Care Inc. Balloon Catheter Analyte Measurement Sensors and Methods for Using the Same
USD924406S1 (en) * 2010-02-01 2021-07-06 Abbott Diabetes Care Inc. Analyte sensor inserter
US9041730B2 (en) 2010-02-12 2015-05-26 Dexcom, Inc. Receivers for analyzing and displaying sensor data
US20130060107A1 (en) 2010-02-19 2013-03-07 Barry Colin Crane Subcutaneous glucose sensor
US20110208027A1 (en) 2010-02-23 2011-08-25 Roche Diagnostics Operations, Inc. Methods And Systems For Providing Therapeutic Guidelines To A Person Having Diabetes
GB201003581D0 (en) 2010-03-04 2010-04-21 Bacon Raymond J Medicament dispenser
US10448872B2 (en) 2010-03-16 2019-10-22 Medtronic Minimed, Inc. Analyte sensor apparatuses having improved electrode configurations and methods for making and using them
EP4248866A3 (en) * 2010-03-24 2023-12-20 Abbott Diabetes Care, Inc. Medical device inserters
JP2013524872A (ja) * 2010-03-24 2013-06-20 アボット ダイアベティス ケア インコーポレイテッド 医療用装置挿入器、並びに医療用装置の挿入方法および使用方法
CN102844060A (zh) 2010-03-30 2012-12-26 犹诺医药有限公司 医疗装置
WO2011123305A2 (en) 2010-03-31 2011-10-06 Animas Corporation Method and system to display analyte sensor data
CN103654740B (zh) 2010-04-05 2017-07-18 Kaz欧洲有限公司 用于医疗探针的插入检测器
WO2011130545A1 (en) 2010-04-16 2011-10-20 Abbott Diabetes Care Inc. Analyte monitoring device and methods
US9198623B2 (en) 2010-04-22 2015-12-01 Abbott Diabetes Care Inc. Devices, systems, and methods related to analyte monitoring and management
WO2011149857A1 (en) 2010-05-24 2011-12-01 Abbott Diabetes Care Inc. Method and system for updating a medical device
KR20130136907A (ko) 2010-06-01 2013-12-13 어뎁턴스, 엘엘씨 네트워크 연결된 착용가능한 의료용 센서를 위한 시스템 및 방법
US9336353B2 (en) 2010-06-25 2016-05-10 Dexcom, Inc. Systems and methods for communicating sensor data between communication devices of a glucose monitoring system
US11064921B2 (en) 2010-06-29 2021-07-20 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
US20110319738A1 (en) 2010-06-29 2011-12-29 Abbott Diabetes Care Inc. Medical Devices and Insertion Systems and Methods
EP2415395A1 (de) 2010-08-04 2012-02-08 Roche Diagnostics GmbH Medizinische Vorrichtung mit Aufnahmekanal für Körperflüssigkeit
EP3632308B1 (en) 2010-09-29 2023-12-06 Dexcom, Inc. Advanced continuous analyte monitoring system
EP2436311A1 (en) 2010-10-04 2012-04-04 PharmaSens AG Diagnostic device
EP2624745A4 (en) * 2010-10-07 2018-05-23 Abbott Diabetes Care, Inc. Analyte monitoring devices and methods
EP2632334B1 (en) 2010-10-27 2020-09-09 Dexcom, Inc. Continuous analyte monitor data recording device operable in a blinded mode
US20120116322A1 (en) 2010-11-06 2012-05-10 IntriMed Technologies, Inc. Method to fabricate a needle having a tapered portion between a distal tip and a longitudinal channel
US8784383B2 (en) 2010-11-30 2014-07-22 Becton, Dickinson And Company Insulin pump dermal infusion set having partially integrated mechanized cannula insertion with disposable activation portion
US20120165640A1 (en) 2010-12-23 2012-06-28 Roche Diagnostics Operations, Inc. Structured blood glucose testing performed on handheld diabetes management devices
USD668164S1 (en) 2011-02-04 2012-10-02 Crestron Electronics Inc. Battery powered occupancy sensor
USD694397S1 (en) 2011-02-28 2013-11-26 Abbott Diabetes Care Inc. Medical device inserter
US10136845B2 (en) 2011-02-28 2018-11-27 Abbott Diabetes Care Inc. Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same
CN107019515B (zh) 2011-02-28 2021-02-26 雅培糖尿病护理公司 显示传感器读数的方法与分析物监测装置及其操作方法
WO2012118872A2 (en) 2011-02-28 2012-09-07 Abbott Diabetes Care Inc. Medical device inserters and processes of inserting and using medical devices
EP2683291B1 (en) 2011-03-11 2019-07-31 Proteus Digital Health, Inc. Wearable personal body associated device with various physical configurations
EP2693945B1 (en) 2011-04-08 2019-03-13 Dexcom, Inc. Systems and methods for processing and transmitting sensor data
ES2847578T3 (es) 2011-04-15 2021-08-03 Dexcom Inc Calibración avanzada de sensor de analito y detección de errores
USD691710S1 (en) 2011-05-23 2013-10-15 Abbott Diabetes Care Inc. Medical device inserter
DK2720610T3 (da) 2011-06-17 2025-09-15 Abbott Diabetes Care Inc Stablet analytsensor med en første elektrode der er smallere end sensorens anden elektrode
US10575762B2 (en) 2011-08-05 2020-03-03 Dexcom, Inc. Systems and methods for detecting glucose level data patterns
CN103957962B (zh) 2011-10-05 2017-07-07 犹诺医药有限公司 用于同时插入多个经皮部分的插入物
US8882665B2 (en) 2011-10-26 2014-11-11 Medtronic Minimed, Inc. Method and/or system for multicompartment analyte monitoring
WO2013066873A1 (en) 2011-10-31 2013-05-10 Abbott Diabetes Care Inc. Electronic devices having integrated reset systems and methods thereof
US8710993B2 (en) 2011-11-23 2014-04-29 Abbott Diabetes Care Inc. Mitigating single point failure of devices in an analyte monitoring system and methods thereof
DK3831283T3 (da) * 2011-12-11 2023-05-30 Abbott Diabetes Care Inc Analytsensorindretninger, forbindelser og fremgangsmåder
FI3662965T3 (fi) 2011-12-30 2024-07-10 Abbott Diabetes Care Inc Menetelmä ja laitteisto lääkkeen annostustiedon määrittämiseksi
US9027419B2 (en) 2012-02-07 2015-05-12 Eppendorf Ag Pipette
US20130235166A1 (en) 2012-03-07 2013-09-12 Cambridge Silicon Radio Limited Synchronisation method
WO2013136968A1 (ja) 2012-03-13 2013-09-19 テルモ株式会社 センサ挿入装置及びその装置の動作方法
US20130267812A1 (en) * 2012-04-04 2013-10-10 Dexcom, Inc. Transcutaneous analyte sensors, applicators therefor, and associated methods
EP2650032A1 (en) 2012-04-11 2013-10-16 PharmaSens AG Subcutaneous needle insertion mechanism
WO2013192177A1 (en) 2012-06-18 2013-12-27 Facet Technologies, Llc Uni-directional drive mechanism for lancing device
USD683209S1 (en) * 2012-06-21 2013-05-28 Emily Garr Gottschalk Blister package
US20150326072A1 (en) 2014-05-07 2015-11-12 Energous Corporation Boost-Charger-Boost System for Enhanced Power Delivery
WO2014018928A1 (en) 2012-07-27 2014-01-30 Abbott Diabetes Care Inc. Medical device applicators
US8930028B2 (en) 2012-07-27 2015-01-06 Roche Diagnostics Operations, Inc. Handheld medical device functionality without battery
US10132793B2 (en) 2012-08-30 2018-11-20 Abbott Diabetes Care Inc. Dropout detection in continuous analyte monitoring data during data excursions
ES2978657T3 (es) 2012-12-18 2024-09-17 Abbott Diabetes Care Inc Dispositivos y procedimientos para la detección de analitos en la capa dérmica
USD711541S1 (en) * 2013-01-15 2014-08-19 4A Medicom Gmbh Body fluid testing device
WO2014143452A1 (en) 2013-03-15 2014-09-18 Abbott Diabetes Care Inc. In vivo glucose sensing in an increased perfusion dermal layer
DE202014011590U1 (de) * 2013-04-30 2023-01-10 Abbott Diabetes Care, Inc. Systeme und Vorrichtungen zur energieeffizienten Aktivierung elektrischer Vorrichtungen
USD782295S1 (en) * 2013-06-21 2017-03-28 John Lee Saw blade container
USD731334S1 (en) 2013-08-20 2015-06-09 Fibar Group sp. z o.o. Flood sensor
US9504471B2 (en) 2013-09-25 2016-11-29 Cybersonics, Inc. Ultrasonic generator systems and methods
EP3957345B1 (en) 2013-10-24 2025-12-10 Amgen Inc. Drug delivery system with temperature-sensitive control
CN104887242B (zh) 2014-03-07 2018-08-28 上海移宇科技股份有限公司 分析物传感系统
CN106687040B (zh) 2014-07-18 2020-06-09 贝克顿·迪金森公司 第一滴去除型刺血针装置
RU2017101849A (ru) 2014-07-22 2018-08-22 Ф.Хоффманн-Ля Рош Аг Устройство для введения сенсора с защитой от повторного использования
EP2979623A1 (en) 2014-07-28 2016-02-03 Roche Diagnostics GmbH Medical sensor assembly
US10321858B2 (en) 2014-08-18 2019-06-18 Proteadx, Inc. Apparatus and methods for transdermal sensing of analytes in interstitial fluid and associated data transmission systems
US11219413B2 (en) * 2014-08-26 2022-01-11 Dexcom, Inc. Systems and methods for securing a continuous analyte sensor to a host
US10327679B2 (en) 2014-09-03 2019-06-25 Nova Biomedical Corporation Subcutaneous sensor inserter and method
CA162350S (en) 2014-11-14 2016-08-29 Farmshed Labs Ltd Sensing device
CA2970517C (en) 2014-12-11 2023-10-10 Facet Technologies, Llc Needle with multi-bevel tip geometry
JP6618486B2 (ja) 2015-01-27 2019-12-11 テルモ株式会社 センサ挿入装置及びセンサ挿入装置セット
JP6618487B2 (ja) 2015-01-27 2019-12-11 テルモ株式会社 センサ挿入装置セット及びベースプレート
US10765361B2 (en) 2015-03-02 2020-09-08 Verily Life Sciences Llc Automated sequential injection and blood draw
CN107205702B (zh) 2015-03-11 2020-05-01 泰尔茂株式会社 传感器插入装置以及更换件
USD747110S1 (en) * 2015-03-19 2016-01-12 3M Innovative Properties Company Display base
CN107708559A (zh) 2015-04-29 2018-02-16 精密公司 样本收集和递送装置
US10213139B2 (en) 2015-05-14 2019-02-26 Abbott Diabetes Care Inc. Systems, devices, and methods for assembling an applicator and sensor control device
CA2984939A1 (en) 2015-05-14 2016-11-17 Abbott Diabetes Care Inc. Compact medical device inserters and related systems and methods
US20160338628A1 (en) 2015-05-22 2016-11-24 Dexcom, Inc. Needle for transcutaneous analyte sensor delivery
EP3560412B1 (en) 2015-08-11 2020-11-18 Trice Medical, Inc. Fully integrated disposable tissue visualization device
USD775987S1 (en) 2015-09-08 2017-01-10 Nix Sensor Ltd. Egg cover
CA169913S (en) * 2015-09-30 2016-11-01 Misfit Inc Activity monitoring device
US20170112534A1 (en) 2015-10-21 2017-04-27 Dexcom, Inc. Transcutaneous analyte sensors, applicators therefor, and associated methods
US20170127985A1 (en) 2015-11-11 2017-05-11 Medtronic Minimed, Inc. Sensor set
USD806254S1 (en) 2015-12-07 2017-12-26 Samsung Electronics Co., Ltd. Apparatus for medical diagnosis
KR20170068694A (ko) 2015-12-09 2017-06-20 (주)진바이오텍 생균제 기능을 지니는 신규 천연 소독제
EP3804611B1 (en) 2015-12-30 2024-07-17 Dexcom, Inc. Transcutaneous analyte sensor systems and methods
US20170216536A1 (en) 2016-02-01 2017-08-03 Scott Science, LLC Needle with cutting blade
RS66282B1 (sr) 2016-02-05 2025-01-31 Hoffmann La Roche Medicinski uređaj za detekciju najmanje jednog analita u telesnoj tečnosti
US10765348B2 (en) 2016-04-08 2020-09-08 Medtronic Minimed, Inc. Sensor and transmitter product
US10631787B2 (en) 2016-04-08 2020-04-28 Medtronic Minimed, Inc. Sensor and transmitter product
US20170290535A1 (en) 2016-04-08 2017-10-12 Medtronic Minimed, Inc. Analyte sensor with indicators
US10765369B2 (en) 2016-04-08 2020-09-08 Medtronic Minimed, Inc. Analyte sensor
US11369412B2 (en) 2016-04-27 2022-06-28 Phc Holdings Corporation Sensor insertion device and biosensor
JP2017202234A (ja) 2016-05-13 2017-11-16 パナソニックヘルスケアホールディングス株式会社 バイオセンサ
USD798170S1 (en) 2016-07-08 2017-09-26 LifeLens Technologies, LLC. Wearable physiological measurement device
EP4566537A3 (en) 2016-10-31 2025-08-20 DexCom, Inc. Transcutaneous analyte sensor systems and methods
USD810952S1 (en) 2016-11-25 2018-02-20 Raymond Hsu Transcutaneous electrical nerve stimulation or TENS device
USD824034S1 (en) 2016-12-15 2018-07-24 Sano Intelligence, Inc. Biomonitoring interface device
WO2018136898A1 (en) 2017-01-23 2018-07-26 Abbott Diabetes Care Inc. Systems, devices and methods for analyte sensor insertion
USD854146S1 (en) * 2017-03-09 2019-07-16 Amgen Inc. Handheld drug delivery device
HUE061067T2 (hu) 2017-03-14 2023-05-28 Hoffmann La Roche Implantátumbehelyezõ tû
JP7061627B2 (ja) 2017-06-02 2022-04-28 アイセンス，インコーポレーテッド 連続血糖測定器用センサーアプリケーター組立体
EP4647086A3 (en) 2017-06-19 2025-12-31 DexCom, Inc. APPLICATORS DESIGNED FOR APPLYING TRANSCUTANEOUS ANALYTE SENSORS
US10863944B2 (en) 2017-06-23 2020-12-15 Dexcom, Inc. Transcutaneous analyte sensors, applicators therefor, and associated methods
WO2019008896A1 (ja) 2017-07-05 2019-01-10 テルモ株式会社 センサ及びセンサの製造方法
FI3668400T3 (fi) * 2017-08-18 2023-08-29 Abbott Diabetes Care Inc Menetelmä analyyttianturien yksilölliseen kalibrointiin
US11197625B1 (en) 2017-11-16 2021-12-14 Verily Life Sciences Llc Apparatus for automated glucose tolerance testing
WO2019195661A1 (en) * 2018-04-06 2019-10-10 Zense-Life Inc. Continuous glucose monitoring device
USD879969S1 (en) * 2018-05-11 2020-03-31 Undercover Colors, Inc. Detection apparatus
CN119924827A (zh) 2018-06-07 2025-05-06 雅培糖尿病护理公司 用于分析物监测系统的聚焦灭菌和已灭菌的子组件
EP4218567B1 (en) 2018-06-07 2025-03-12 Abbott Diabetes Care, Inc. Focused sterilization and sterilized sub-assemblies for analyte monitoring systems
USD888252S1 (en) * 2018-06-18 2020-06-23 Dexcom, Inc. Transcutaneous analyte sensor applicator
USD926325S1 (en) * 2018-06-22 2021-07-27 Dexcom, Inc. Wearable medical monitoring device
KR102222049B1 (ko) 2018-09-27 2021-03-04 주식회사 아이센스 연속 혈당 측정 장치용 어플리케이터
US12521041B2 (en) * 2018-12-21 2026-01-13 Abbott Diabetes Care Inc. Systems, devices, and methods for analyte sensor insertion
JP7598861B2 (ja) * 2019-01-04 2024-12-12 アボット ダイアベティス ケア インコーポレイテッド 分析物監視システムの食事および治療インタフェースを改善するためのシステム、デバイス、および方法
EP4643905A3 (en) 2019-02-22 2026-01-21 DEKA Products Limited Partnership Inserter assembly for infusion sets
JP2020151237A (ja) 2019-03-20 2020-09-24 Ｐｈｃホールディングス株式会社 生体情報測定装置
EP3733064B1 (en) * 2019-04-30 2024-04-10 Roche Diabetes Care GmbH Continuous analyte sensor with magnetic activation
USD1002852S1 (en) * 2019-06-06 2023-10-24 Abbott Diabetes Care Inc. Analyte sensor device
TWI729670B (zh) 2019-08-02 2021-06-01 華廣生技股份有限公司 生物感測器之植入裝置
TWI885048B (zh) * 2020-01-24 2025-06-01 瑞士商安晟信醫療科技控股公司 無菌可重複使用可穿戴裝置及在持續分析物監控中的可穿戴裝置形成方法
US20210369152A1 (en) * 2020-06-02 2021-12-02 Ascensia Diabetes Care Holdings Ag Methods and apparatus configured to transmit data in continuous analyte monitors
CN115023184A (zh) * 2020-06-04 2022-09-06 健臻糖尿病护理控股有限公司 用于连续分析物监测系统的信号的时变滤波的方法和设备
US11272884B2 (en) 2020-06-04 2022-03-15 Medtronic Minimed, Inc. Liner for adhesive skin patch
AU2021332055A1 (en) 2020-08-31 2023-02-23 Abbott Diabetes Care Inc. Systems, devices, and methods for analyte sensor applicators
US12239463B2 (en) 2020-08-31 2025-03-04 Abbott Diabetes Care Inc. Systems, devices, and methods for analyte sensor insertion
CA3186905A1 (en) 2020-09-15 2022-03-24 Abbott Diabetes Care Inc. Systems, devices, and methods for an analyte sensor
MY205396A (en) 2020-09-15 2024-10-19 Abbott Diabetes Care Inc System, apparatus, and devices for analyte monitoring
US20220273240A1 (en) 2021-02-26 2022-09-01 Laxmi Therapeutic Devices, Inc. Needle sensor and method of manufacturing the same
AU2022310377A1 (en) 2021-07-16 2024-01-04 Abbott Diabetes Care Inc. Systems, devices, and methods for analyte monitoring

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060020189A1 (en) * 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
US20090054866A1 (en) * 2005-01-24 2009-02-26 Novo Nordisk A/S Transcutaneous Device Assembly
US20080167578A1 (en) * 2005-11-30 2008-07-10 Abbott Diabetes Care, Inc. Integrated Meter for Analyzing Biological Samples
US20080114280A1 (en) * 2006-10-23 2008-05-15 Gary Ashley Stafford Variable speed sensor insertion devices and methods of use
US20090198215A1 (en) * 2007-04-30 2009-08-06 Medtronic Minimed, Inc. Adhesive patch systems and methods

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11296731B2 (en) 2018-03-07 2022-04-05 Phc Holdings Corporation Communication device
US12555660B2 (en) 2019-08-02 2026-02-17 Abbott Diabetes Care Inc. Systems, devices, and methods relating to medication dose guidance
US12128213B2 (en) 2020-01-30 2024-10-29 Willow Laboratories, Inc. Method of operating redundant staggered disease management systems

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