HRP20150979T1 - Više-podruäśni i ispitni senzori za potencijal, postupci i sustavi - Google Patents

Više-podruäśni i ispitni senzori za potencijal, postupci i sustavi Download PDF

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Publication number
HRP20150979T1
HRP20150979T1 HRP20150979TT HRP20150979T HRP20150979T1 HR P20150979 T1 HRP20150979 T1 HR P20150979T1 HR P20150979T T HRP20150979T T HR P20150979TT HR P20150979 T HRP20150979 T HR P20150979T HR P20150979 T1 HRP20150979 T1 HR P20150979T1
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Croatia
Prior art keywords
test sensor
sensor according
secondary analysis
redox
counter electrodes
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HRP20150979TT
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English (en)
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Huan Ping Wu
Weiping Zhong
Joseph E. Perry
Eric Maurer
Sung-Kwon Jung
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Bayer Healthcare Llc
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Publication of HRP20150979T1 publication Critical patent/HRP20150979T1/hr

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • Electrochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measurement Of Current Or Voltage (AREA)

Claims (13)

1. Ispitni senzor za analit (700), naznačen time da sadrži: najmanje dva supstrata koja oblikuju spremnik, te spremnik ima primarno područje (710) između osam uglavnom kemijski izoliranih sekundarnih područja analize, gdje se difuzijsko ili konvektivno miješanje reagenasa uglavnom ne javlja između sekundarnih područja analize tijekom vremena jedne ili više analiza; četiri radne elektrode (841-844), koje svaka uključuju prvi vodič i pripravak reagensa raspoređen u odvojena sekundarna područja analize, gdje svaka radna elektroda (841-844) ima najmanje jedan pripravak reagensa s različitim redoks potencijalom; i četiri protu elektrode (731-734), koje svaka uključuju drugi vodič i najmanje jednu redoks vrstu raspoređenu u odvojena sekundarna područja analize; gdje su prvi vodiči radnih elektroda (841-844) električno spojeni, gdje drugi vodiči protu elektroda (731-734) nisu električno spojeni, te ih je moguće neovisno adresirati.
2. Ispitni senzor prema zahtjevu 1, naznačen time da osnovno područje (710) uglavnom razdvaja uglavnom kemijski izolirana sekundarna područja.
3. Ispitni senzor prema zahtjevu 2, naznačen time da su sekundarna područja analize raspoređena na suprotnim stranama osnovnog područja (710).
4. Ispitni senzor prema zahtjevu 3, naznačen time da se sekundarna područja analize granaju od osnovnog područja (710) pod kutom od 90°.
5. Ispitni senzor prema bilo kojem od prethodnih zahtjeva, naznačen time da svako sekundarno područje analize ima jednu elektrodu.
6. Ispitni senzor prema zahtjevu 2, naznačen time da su četiri radne elektrode (841-844) raspoređene u sekundarna područja analize na jednoj strani osnovnog područja (710), i gdje su četiri protu elektrode (731-734) raspoređene u sekundarna područja analize na drugoj strani osnovnog područja (710).
7. Ispitni senzor prema bilo kojem od prethodnih zahtjeva, dodatno naznačen time da ima drugi vodič (790) spojen na jednu od protu elektroda (731-734) i proteže se u osnovno područje (710).
8. Ispitni senzor prema bilo kojem od prethodnih zahtjeva, naznačen time da su protu elektrode (731-734) konfigurirane da radne na različitim potencijalima odvojenim za najmanje 50 mV.
9. Ispitni senzor prema bilo kojem od prethodnih zahtjeva, naznačen time da su redoks vrste odabrane iz skupine koja sadrži metal nasuprot elektroaktivne organske molekule i elementarni identitet metala.
10. Ispitni senzor prema bilo kojem od zahtjeva 1 do 8, naznačen time da je predviđena različita konfiguracija potencijala sa redoks vrstama koje imaju različite omjere konjugata za redoks par.
11. Ispitni senzor prema bilo kojem od prethodnih zahtjeva, dodatno naznačen time da ima najmanje jednu referentnu elektrodu (770) u osnovnom području (710).
12. Ispitni senzor prema bilo kojem od prethodnih zahtjeva, naznačen time da pripravak reagensa uključuje enzimski sustav, posrednik, i vezivo; te gdje svaka protu elektroda (731-734) sadrži uglavnom drugi vodič, najmanje jednu redoks vrstu, te vezivo.
13. Ispitni senzor prema zahtjevu 1, naznačen time da svaka radna elektroda (841-844) ima dva ili četiri pripravka reagensa koji imaju različite redoks potencijale.
HRP20150979TT 2007-09-24 2015-09-16 Više-podruäśni i ispitni senzori za potencijal, postupci i sustavi HRP20150979T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97482307P 2007-09-24 2007-09-24
PCT/US2008/077434 WO2009042631A2 (en) 2007-09-24 2008-09-24 Multi-electrode test sensors
EP08832808.3A EP2205964B1 (en) 2007-09-24 2008-09-24 Multi-region and potential test sensors, methods, and systems

Publications (1)

Publication Number Publication Date
HRP20150979T1 true HRP20150979T1 (hr) 2015-11-20

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Country Link
US (2) US9846136B2 (hr)
EP (7) EP3193162B1 (hr)
JP (4) JP5523323B2 (hr)
CN (3) CN111505091A (hr)
BR (1) BRPI0817189A2 (hr)
CA (3) CA2984510C (hr)
DK (1) DK2205964T3 (hr)
ES (5) ES2636676T3 (hr)
HR (1) HRP20150979T1 (hr)
MX (1) MX2010003205A (hr)
PL (4) PL2535704T3 (hr)
RU (1) RU2490622C2 (hr)
WO (1) WO2009042631A2 (hr)

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