SI1407044T2 - Rna interference mediating small rna molecules - Google Patents

Rna interference mediating small rna molecules Download PDF

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Publication number
SI1407044T2
SI1407044T2 SI200130787T SI200130787T SI1407044T2 SI 1407044 T2 SI1407044 T2 SI 1407044T2 SI 200130787 T SI200130787 T SI 200130787T SI 200130787 T SI200130787 T SI 200130787T SI 1407044 T2 SI1407044 T2 SI 1407044T2
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Slovenia
Prior art keywords
rna
rna molecule
double
gene
target
Prior art date
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SI200130787T
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English (en)
Slovenian (sl)
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SI1407044T1 (sl
Inventor
Thomas Tuschl
Sayda Elbashir
Winfried Lendeckel
Matthias Wilm
Reinhard Luhrmann
Original Assignee
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V.
Europaisches Laboratorium Fur Molekularbiologie
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40529293&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1407044(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/US2001/010188 external-priority patent/WO2001075164A2/en
Application filed by Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V., Europaisches Laboratorium Fur Molekularbiologie filed Critical Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V.
Publication of SI1407044T1 publication Critical patent/SI1407044T1/sl
Publication of SI1407044T2 publication Critical patent/SI1407044T2/en

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • A—HUMAN NECESSITIES
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    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/53—Physical structure partially self-complementary or closed
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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SI200130787T 2000-12-01 2001-11-29 Rna interference mediating small rna molecules SI1407044T2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP00126325 2000-12-01
US27966101P 2001-03-30 2001-03-30
PCT/US2001/010188 WO2001075164A2 (en) 2000-03-30 2001-03-30 Rna sequence-specific mediators of rna interference
PCT/EP2001/013968 WO2002044321A2 (en) 2000-12-01 2001-11-29 Rna interference mediating small rna molecules
EP01985833.1A EP1407044B2 (en) 2000-12-01 2001-11-29 Rna interference mediating small rna molecules

Publications (2)

Publication Number Publication Date
SI1407044T1 SI1407044T1 (sl) 2008-04-30
SI1407044T2 true SI1407044T2 (en) 2018-03-30

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SI200130787T SI1407044T2 (en) 2000-12-01 2001-11-29 Rna interference mediating small rna molecules

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US (25) US20040259247A1 (enExample)
EP (3) EP2348133B1 (enExample)
JP (5) JP4095895B2 (enExample)
KR (2) KR100909681B1 (enExample)
CN (1) CN100523215C (enExample)
AT (1) ATE373724T2 (enExample)
AU (3) AU2002235744B8 (enExample)
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CA (1) CA2429814C (enExample)
CY (1) CY1119062T1 (enExample)
CZ (2) CZ308053B6 (enExample)
DE (1) DE60130583T3 (enExample)
DK (2) DK1407044T4 (enExample)
ES (2) ES2728168T3 (enExample)
HU (1) HU230458B1 (enExample)
IL (3) IL155991A0 (enExample)
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PT (1) PT1407044E (enExample)
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TR (1) TR200401292T3 (enExample)
WO (1) WO2002044321A2 (enExample)
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US20100316703A1 (en) 2010-12-16
HK1139181A1 (en) 2010-09-10
JP4095895B2 (ja) 2008-06-04
CZ302719B6 (cs) 2011-09-21
PT1407044E (pt) 2008-01-02
CA2429814C (en) 2014-02-18
EP1873259A1 (en) 2008-01-02
US20110070162A1 (en) 2011-03-24
SI1407044T1 (sl) 2008-04-30
JP2007111053A (ja) 2007-05-10
CZ2011452A3 (enExample) 2003-10-15
ATE373724T2 (de) 2007-10-15
WO2002044321A2 (en) 2002-06-06
JP5749892B2 (ja) 2015-07-15
DK2813582T3 (en) 2017-07-31
ZA200303929B (en) 2004-07-19
TR200401292T3 (tr) 2004-07-21
EP1873259B1 (en) 2012-01-25
US8895721B2 (en) 2014-11-25
KR100909681B1 (ko) 2009-07-29
NO20032464L (no) 2003-07-21
US20110065773A1 (en) 2011-03-17
EP2348133A1 (en) 2011-07-27
JP2004526422A (ja) 2004-09-02
HK1204798A1 (en) 2015-12-04
HU230458B1 (hu) 2016-07-28
PL218876B1 (pl) 2015-02-27
KR100872437B1 (ko) 2008-12-05
US8796016B2 (en) 2014-08-05
AU2010212438B2 (en) 2013-05-09
US10633656B2 (en) 2020-04-28
US7078196B2 (en) 2006-07-18
DK1407044T3 (da) 2008-01-28
JP2015061534A (ja) 2015-04-02
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US20100010207A1 (en) 2010-01-14
WO2002044321A3 (en) 2003-10-23
US20040229266A1 (en) 2004-11-18
CZ308053B6 (cs) 2019-11-27
JP2010131031A (ja) 2010-06-17
CN100523215C (zh) 2009-08-05
EP1407044B2 (en) 2017-11-15
RU2322500C2 (ru) 2008-04-20
IL155991A0 (en) 2003-12-23
RU2007131270A (ru) 2009-02-27
PL365784A1 (pl) 2005-01-10
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US8778902B2 (en) 2014-07-15
HUP0302557A3 (en) 2005-12-28
CZ20031839A3 (cs) 2003-10-15
BRPI0115814B8 (pt) 2021-05-25
AU2010212438A1 (en) 2010-09-09
IL155991A (en) 2013-06-27
NZ525888A (en) 2006-04-28
US8329463B2 (en) 2012-12-11
KR20080069602A (ko) 2008-07-28
US20110065109A1 (en) 2011-03-17
AU2002235744B8 (en) 2007-06-28
US20040259248A1 (en) 2004-12-23
EP2348133B1 (en) 2014-07-16
US20200299693A1 (en) 2020-09-24
US8372968B2 (en) 2013-02-12
US20050026278A1 (en) 2005-02-03
JP6189576B2 (ja) 2017-08-30
DE60130583T2 (de) 2008-06-12
AU2007203385A1 (en) 2007-08-09
NO333713B1 (no) 2013-09-02
AU2007203385B2 (en) 2010-05-20
AU2010212438A2 (en) 2010-09-23
US20050234007A1 (en) 2005-10-20
US8895718B2 (en) 2014-11-25
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DK1407044T4 (en) 2017-12-04
US8853384B2 (en) 2014-10-07
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US8445237B2 (en) 2013-05-21
AU2002235744B2 (en) 2007-04-19
US20130125259A1 (en) 2013-05-16
JP6325974B2 (ja) 2018-05-16
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US8765930B2 (en) 2014-07-01
LTPA2021005I1 (enExample) 2021-06-10
US8362231B2 (en) 2013-01-29
US20110027883A1 (en) 2011-02-03
US20100292456A1 (en) 2010-11-18
RU2470073C2 (ru) 2012-12-20
DE60130583D1 (de) 2007-10-31
BR0115814A (pt) 2004-03-23
CY1119062T1 (el) 2018-01-10
US20090155174A1 (en) 2009-06-18
US7056704B2 (en) 2006-06-06
HUP0302557A2 (hu) 2003-10-28
US20050234006A1 (en) 2005-10-20
US20110020234A1 (en) 2011-01-27
US8933044B2 (en) 2015-01-13
KR20040012686A (ko) 2004-02-11

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