RU2322500C2 - Малые молекулы рнк, опосредующие интерференцию рнк - Google Patents

Малые молекулы рнк, опосредующие интерференцию рнк Download PDF

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RU2322500C2
RU2322500C2 RU2003119457/13A RU2003119457A RU2322500C2 RU 2322500 C2 RU2322500 C2 RU 2322500C2 RU 2003119457/13 A RU2003119457/13 A RU 2003119457/13A RU 2003119457 A RU2003119457 A RU 2003119457A RU 2322500 C2 RU2322500 C2 RU 2322500C2
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rna
target
gene
cell
sirna
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RU2003119457/13A
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Russian (ru)
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RU2003119457A (ru
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Томас ТУШЛЬ (DE)
Томас ТУШЛЬ
Зайда ЭЛЬБАШИР (DE)
Зайда ЭЛЬБАШИР
Винфрид ЛЕНДЕККЕЛЬ (DE)
Винфрид ЛЕНДЕККЕЛЬ
Маттиас ВИЛЬМ (DE)
Маттиас ВИЛЬМ
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Макс-Планк-Гезелльшафт Цур Фердерунг Дер Виссеншафтен Е.Ф.
Ойропэишес Лабораториум Фюр Молекулярбиологи (Ембл)
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Priority claimed from PCT/US2001/010188 external-priority patent/WO2001075164A2/en
Application filed by Макс-Планк-Гезелльшафт Цур Фердерунг Дер Виссеншафтен Е.Ф., Ойропэишес Лабораториум Фюр Молекулярбиологи (Ембл) filed Critical Макс-Планк-Гезелльшафт Цур Фердерунг Дер Виссеншафтен Е.Ф.
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RU2003119457/13A 2000-12-01 2001-11-29 Малые молекулы рнк, опосредующие интерференцию рнк RU2322500C2 (ru)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP00126325.0 2000-12-01
EP00126325 2000-12-01
US27966101P 2001-03-30 2001-03-30
USPCT/US01/10188 2001-03-30
PCT/US2001/010188 WO2001075164A2 (en) 2000-03-30 2001-03-30 Rna sequence-specific mediators of rna interference
US60/279,661 2001-03-30

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RU2003119457A RU2003119457A (ru) 2004-12-20
RU2322500C2 true RU2322500C2 (ru) 2008-04-20

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RU2003119457/13A RU2322500C2 (ru) 2000-12-01 2001-11-29 Малые молекулы рнк, опосредующие интерференцию рнк
RU2007131270/10A RU2470073C2 (ru) 2000-12-01 2007-08-16 Малые молекулы рнк, опосредующие интерференцию рнк

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Cited By (4)

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US8329463B2 (en) 2000-12-01 2012-12-11 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. RNA interference mediating small RNA molecules
US8394628B2 (en) 2000-03-30 2013-03-12 University Of Massachusetts RNA sequence-specific mediators of RNA interference
RU2501859C2 (ru) * 2008-03-31 2013-12-20 Нэшнл Инститьют Оф Эдванст Индастриал Сайенс Энд Текнолоджи Модифицированная липидами двухцепочечная рнк, обладающая мощным эффектом рнк-интерференции
RU2842959C2 (ru) * 2012-04-10 2025-07-04 Элнилэм Фармасьютикалз, Инк. Композиции и способы ингибирования экспрессии гена alas1

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US20030206887A1 (en) * 1992-05-14 2003-11-06 David Morrissey RNA interference mediated inhibition of hepatitis B virus (HBV) using short interfering nucleic acid (siNA)
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ATE526405T1 (de) 1998-03-20 2011-10-15 Commw Scient Ind Res Org Synthetische gene und genetische zusammensetzungen diesen enthaltend
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DE10100586C1 (de) 2001-01-09 2002-04-11 Ribopharma Ag Verfahren zur Hemmung der Expression eines Ziegens
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US20080039414A1 (en) * 2002-02-20 2008-02-14 Sima Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
US20050032733A1 (en) * 2001-05-18 2005-02-10 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SiNA)
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JP2003526367A (ja) * 2000-03-16 2003-09-09 ジェネティカ インコーポレイテッド Ｒｎａ干渉の方法とｒｎａ干渉組成物
EP2361981B2 (en) * 2000-03-30 2019-01-23 The Whitehead Institute for Biomedical Research RNA sequence-specific mediators of RNA interference
US20080242627A1 (en) * 2000-08-02 2008-10-02 University Of Southern California Novel rna interference methods using dna-rna duplex constructs
US7662791B2 (en) * 2000-08-02 2010-02-16 University Of Southern California Gene silencing using mRNA-cDNA hybrids
DK1363938T3 (en) * 2000-08-03 2014-03-24 Univ Johns Hopkins Molecular vaccine that connects an endoplasmic reticulum-chaperonepolypeptid with an antigen
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US8546143B2 (en) 2001-01-09 2013-10-01 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of a target gene
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