DK3597644T3 - Kationiske aminlipider og anvendelser deraf - Google Patents
Kationiske aminlipider og anvendelser deraf Download PDFInfo
- Publication number
- DK3597644T3 DK3597644T3 DK19191168.4T DK19191168T DK3597644T3 DK 3597644 T3 DK3597644 T3 DK 3597644T3 DK 19191168 T DK19191168 T DK 19191168T DK 3597644 T3 DK3597644 T3 DK 3597644T3
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- aminlipids
- cationic
- cationic aminlipids
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- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
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- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
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- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
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- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
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- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/61—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms not forming part of a nitro radical, attached to ring nitrogen atoms
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| US201161548598P | 2011-10-18 | 2011-10-18 | |
| EP12841768.0A EP2768958B1 (en) | 2011-10-18 | 2012-10-18 | Amine cationic lipids and uses thereof |
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| DK19191168.4T DK3597644T3 (da) | 2011-10-18 | 2012-10-18 | Kationiske aminlipider og anvendelser deraf |
| DK12841768.0T DK2768958T3 (da) | 2011-10-18 | 2012-10-18 | Kationiske aminlipider og anvendelser deraf |
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-
2012
- 2012-10-18 ES ES19191168T patent/ES2897565T3/es active Active
- 2012-10-18 WO PCT/US2012/060875 patent/WO2013059496A1/en not_active Ceased
- 2012-10-18 CN CN201280061076.4A patent/CN103987847B/zh active Active
- 2012-10-18 JP JP2014537255A patent/JP6294229B2/ja active Active
- 2012-10-18 EP EP12841768.0A patent/EP2768958B1/en active Active
- 2012-10-18 EP EP19191168.4A patent/EP3597644B1/en active Active
- 2012-10-18 DK DK19191168.4T patent/DK3597644T3/da active
- 2012-10-18 CA CA2852917A patent/CA2852917C/en active Active
- 2012-10-18 EP EP21198343.2A patent/EP3960726A1/en active Pending
- 2012-10-18 ES ES12841768T patent/ES2745373T3/es active Active
- 2012-10-18 KR KR1020147013364A patent/KR102011048B1/ko not_active Expired - Fee Related
- 2012-10-18 CN CN201710356481.3A patent/CN107266391B/zh active Active
- 2012-10-18 PT PT191911684T patent/PT3597644T/pt unknown
- 2012-10-18 DK DK12841768.0T patent/DK2768958T3/da active
- 2012-10-18 HU HUE19191168A patent/HUE057604T2/hu unknown
- 2012-10-18 PL PL19191168T patent/PL3597644T3/pl unknown
- 2012-10-18 AU AU2012325997A patent/AU2012325997C1/en not_active Ceased
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- 2014-04-17 US US14/255,637 patent/US9549983B2/en active Active
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- 2018-11-29 US US16/204,053 patent/US11059807B2/en active Active
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- 2021-06-08 US US17/342,281 patent/US20210292303A1/en not_active Abandoned
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