KR20130042043A - 6-변형된 바이시클릭 핵산 유사체 - Google Patents

6-변형된 바이시클릭 핵산 유사체 Download PDF

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KR20130042043A
KR20130042043A KR1020137007796A KR20137007796A KR20130042043A KR 20130042043 A KR20130042043 A KR 20130042043A KR 1020137007796 A KR1020137007796 A KR 1020137007796A KR 20137007796 A KR20137007796 A KR 20137007796A KR 20130042043 A KR20130042043 A KR 20130042043A
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South Korea
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mmol
reaction
nucleoside
hours
room temperature
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KR1020137007796A
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English (en)
Korean (ko)
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에릭 이. 스웨이즈
푸니트 피. 세쓰
Original Assignee
아이시스 파마수티컬즈 인코포레이티드
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Application filed by 아이시스 파마수티컬즈 인코포레이티드 filed Critical 아이시스 파마수티컬즈 인코포레이티드
Publication of KR20130042043A publication Critical patent/KR20130042043A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020137007796A 2006-01-27 2007-01-27 6-변형된 바이시클릭 핵산 유사체 KR20130042043A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US76272206P 2006-01-27 2006-01-27
US60/762,722 2006-01-27
US80566006P 2006-06-23 2006-06-23
US60/805,660 2006-06-23
PCT/US2007/061183 WO2007090071A2 (en) 2006-01-27 2007-01-27 6-modified bicyclic nucleic acid analogs

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020087020907A Division KR101304071B1 (ko) 2006-01-27 2007-01-27 6-변형된 바이시클릭 핵산 유사체

Publications (1)

Publication Number Publication Date
KR20130042043A true KR20130042043A (ko) 2013-04-25

Family

ID=38328111

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020137007796A KR20130042043A (ko) 2006-01-27 2007-01-27 6-변형된 바이시클릭 핵산 유사체
KR1020087020907A KR101304071B1 (ko) 2006-01-27 2007-01-27 6-변형된 바이시클릭 핵산 유사체

Family Applications After (1)

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KR1020087020907A KR101304071B1 (ko) 2006-01-27 2007-01-27 6-변형된 바이시클릭 핵산 유사체

Country Status (13)

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US (3) US7399845B2 (US07399845-20080715-C00055.png)
EP (3) EP1984381B1 (US07399845-20080715-C00055.png)
JP (2) JP5342881B2 (US07399845-20080715-C00055.png)
KR (2) KR20130042043A (US07399845-20080715-C00055.png)
CN (2) CN102908630B (US07399845-20080715-C00055.png)
AT (1) ATE482965T1 (US07399845-20080715-C00055.png)
AU (1) AU2007211080B9 (US07399845-20080715-C00055.png)
CA (1) CA2640171C (US07399845-20080715-C00055.png)
DE (1) DE602007009487D1 (US07399845-20080715-C00055.png)
DK (2) DK1984381T3 (US07399845-20080715-C00055.png)
ES (1) ES2516815T3 (US07399845-20080715-C00055.png)
PL (2) PL2314594T3 (US07399845-20080715-C00055.png)
WO (1) WO2007090071A2 (US07399845-20080715-C00055.png)

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