KR20210144822A - Ube3a-ats를 조절하기 위한 화합물 및 방법 - Google Patents

Ube3a-ats를 조절하기 위한 화합물 및 방법 Download PDF

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KR20210144822A
KR20210144822A KR1020217034760A KR20217034760A KR20210144822A KR 20210144822 A KR20210144822 A KR 20210144822A KR 1020217034760 A KR1020217034760 A KR 1020217034760A KR 20217034760 A KR20217034760 A KR 20217034760A KR 20210144822 A KR20210144822 A KR 20210144822A
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modified oligonucleotide
nucleosides
oligomeric compound
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수잔 엠. 프라이어
후인-호아 부이
페이만 자파-네자드
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아이오니스 파마수티컬즈, 인코포레이티드
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Abstract

세포 또는 대상체에서 유비퀴틴 단백질 리가제 E3A(ubiquitin protein ligase E3A: UBE3A)의 내인성 안티센스 전사체인 UBE3A-ATS의 양 또는 활성을 감소시키고, 특정 예에서는 세포 또는 대상체에서 부계(paternal) UBE3A의 발현 및 UBE3A 단백질의 양을 증가시키기 위한 화합물, 방법 및 약제학적 조성물이 제공된다. 상기 화합물, 방법 및 약제학적 조성물은 신경유전학적 장애의 적어도 하나의 증상 또는 특징을 개선하는데 유용하다. 상기 증상 및 특징은 발달 지연, 운동실조, 언어 장애, 수면 문제, 발작 및 EEG 이상을 포함한다. 상기 신경유전학적 장애는 안젤만 증후군을 포함한다.

Description

UBE3A-ATS를 조절하기 위한 화합물 및 방법
서열목록
본 출원은 전자 형식의 서열 목록과 함께 출원된다. 상기 서열 목록은 크기가 1.87MB이고, 2020년 3월 16일자로 작성된 BIOL0349WOSEQ_ST25.txt의 파일명으로 제공된다. 서열 목록의 이러한 전자 포맷의 정보는 전문이 본 명세서에 참조에 의해 포함된다.
배경기술
세포 또는 대상체에서 유비퀴틴 단백질 리가제 E3A(ubiquitin protein ligase E3A: UBE3A)의 내인성 안티센스 전사체인 UBE3A-ATS의 양 또는 활성을 감소시키고, 특정 예에서는 세포 또는 대상체에서 부계(paternal) UBE3A의 발현 및 UBE3A 단백질의 양을 증가시키기 위한 화합물, 방법 및 약제학적 조성물이 제공된다. 상기 화합물, 방법 및 약제학적 조성물은 신경유전학적 장애의 적어도 하나의 증상 또는 특징을 개선하는데 유용하다. 상기 증상 및 특징은 발달 지연, 운동실조, 언어 장애, 수면 문제, 발작 및 EEG 이상을 포함한다. 상기 신경유전학적 장애는 안젤만 증후군을 포함한다.
안젤만 증후군(Angelman Syndrome: AS)은 대략 15,000명 중 1명의 출생에 영향을 미치는 발달 장애이며, 유비퀴틴 단백질 리가제 E3A(UBE3A)의 결핍으로 인한 것이다. 뉴런에서 UBE3A 유전자의 2개의 카피 중에서, 모계 유전자는 전형적으로 발현되지만, 부계 유전자는 유전자 각인(imprinting) 및 침묵(silencing)에 영향을 받는다. 안젤만 증후군은, 돌연변이, 결실, 15번 염색체의 부계 단친성 이염색체(paternal uniparental disomy) 또는 각인 결함으로 인해서, 부계 UBE3A 유전자의 기능성 카피가 어머니로부터 유전되지 않은 경우에 유발된다(문헌[Buiting, et al., "Angelman Syndrome - insights into a rare neurogenetic disorder", Nature Rev. Neuro., 2016, 12:584-593] 참고).
안젤만 증후군 환자는 발달 지연 및 언어 장애를 경험하고, 일반적으로 수면 문제, 발작 및 EEG 이상을 경험한다. 장애는 생후 수 년 내에 진단되며, 유전 검사에 의해서 진단을 확인할 수 있다. 그러나, 안젤만 증후군을 위한 요법은 제한적이며, 주로 증상 관리에 중점을 둔다(문헌[Williams, C.A. et al., Genet. Med., 12: 385-395, 2010] 참고).
최근에, 암 치료에 현재 사용되는 토포아이소머라제 저해제가 뉴런 배양 시스템 및 마우스 둘 다에서 부계 UBE3A 발현을 "비침묵화(unsilencing)"시킨다는 것을 발견하였다(문헌[Huang, H.S. et al., Nature, 481: 185-189, 2012]). 그러나, 부계 UBE3A 발현의 비침묵화의 정확한 기전은 공지되어 있지 않고, 토포아이소머라제 저해제가 비특이적이고, 단일 가닥 브레이크 및 이중 가닥 브레이크와 같은 DNA 손상을 유도할 수 있는 것으로 공지되어 있기 때문에 이것은 안전성 문제가 많다.
현재 신경유전학적 장애, 예컨대, AS를 치료하기 위한 허용 가능한 선택이 부족하다. 따라서 본 명세서에서는 이러한 질환을 치료하기 위한 화합물, 방법 및 약제학적 조성물을 제공하는 것이 목적이다.
본 명세서에는 UBE3A-ATS RNA의 양 또는 활성을 감소시키고, 특정 실시형태에서는 세포 또는 대상체에서 부계 UBE3A RNA 또는 단백질의 발현을 증가시키기 위한 화합물, 방법 및 약제학적 조성물이 제공된다. 특정 실시형태에서, 대상체는 신경유전학적 장애를 갖는다. 특정 실시형태에서, 대상체는 안젤만 증후군(AS)을 갖는다. 특정 실시형태에서, UBE3A-ATS RNA 또는 이의 일부의 발현을 감소시키는데 유용한 화합물은 올리고머 화합물이다. 특정 실시형태에서, UBE3A-ATS RNA 또는 이의 일부의 발현을 감소시키는데 유용한 화합물은 변형된 올리고뉴클레오타이드이다. 특정 실시형태에서, 부계 UBE3A RNA 또는 단백질의 발현을 증가시키는데 유용한 화합물은 올리고머 화합물이다. 특정 실시형태에서, 부계 UBE3A RNA 또는 단백질의 발현을 증가시키는데 유용한 화합물은 변형된 올리고뉴클레오타이드이다.
또한 신경유전학적 장애의 적어도 하나의 증상 또는 특징을 개선하는데 유용한 방법이 제공된다. 특정 실시형태에서, 신경유전학적 장애는 안젤만 증후군이다. 특정 실시형태에서, 증상 또는 특징은 발달 지연, 운동실조, 언어 장애, 수면 문제, 발작 및/또는 EEG 이상을 포함한다.
전술한 일반적인 설명 및 하기의 상세한 설명은 단지 예시 및 설명을 위한 것이며 제한적인 것이 아님을 이해해야 한다. 본 명세서에서, 단수형의 사용은 달리 특별히 언급되지 않는 한, 복수형을 포함한다. 본 명세서에서 사용된 바와 같이, "또는"의 사용은 달리 언급되지 않는 한, "및/또는"을 의미한다. 더욱이, 용어 "포함하는" 뿐만 아니라 다른 형태들, 예컨대, "포함하다" 및 "포함된"의 사용은 제한적이지 않다. 또한, "요소" 또는 "성분"과 같은 용어는 달리 특별히 언급되지 않는 한, 하나의 단위를 포함하는 요소들 및 성분들 그리고 하나 이상의 소단위를 포함하는 요소들 및 성분들 둘 다를 포함한다.
본 명세서에서 사용된 섹션 제목은 단지 구조화 목적을 위한 것이며 기재된 주제를 제한하는 것으로 해석되어서는 안 된다. 특허, 특허 출원, 기사, 서적 및 논문을 포함하지만 이들로 제한되지 않는 본 출원에 인용된 모든 문서 또는 문서의 일부는 본 명세서에 논의된 문서의 일부뿐만 아니라 그 전문이 명백히 본 명세서에 참조에 의해 포함된다.
정의
특정 정의가 제공되지 않는 한, 본 명세서에 기재된 내용과 관련하여 사용되는 명명법, 및 본 명세서에 기재된 분석 화학, 합성 유기 화학 및 약물 및 제약학적 화학의 절차 및 기술은 당업계에 널리 공지되어 있으며 통상적으로 사용되는 것이다. 허용 가능한 한, 개시내용 전반에 걸쳐 언급되는 모든 특허, 출원, 공개 출원 및 기타 간행물 및 기타 데이터는 그 전문이 본 명세서에 참조에 의해 포함된다.
달리 나타내지 않는 한, 하기 용어는 다음 의미를 갖는다:
정의
본 명세서에서 사용된 바와 같이, "2'-데옥시뉴클레오사이드"는 2'-H(H) 데옥시리보실 당 모이어티를 포함하는 뉴클레오사이드를 의미한다. 특정 실시형태에서, 2'-데옥시뉴클레오사이드는 2'-β-D-데옥시뉴클레오사이드이고, 자연 발생 데옥시리보핵산(DNA)에서 발견되는 바와 같이 β-D 배위를 갖는 2'-β-D-데옥시리보실 당 모이어티를 포함한다. 특정 실시형태에서, 2'-데옥시뉴클레오사이드는 변형된 핵염기를 포함할 수 있거나 또는 RNA 핵염기(유라실)를 포함할 수 있다.
본 명세서에서 사용된 바와 같이, "2'-MOE" 또는 "2'-MOE 당 모이어티"는 리보실 당 모이어티의 2'-OH기 대신 2'-OCH2CH2OCH3 를 의미한다. "MOE"는 메톡시에틸을 의미한다. 달리 제시되지 않는 한, 2'-MOE는 β-D 입체화학 배위를 갖는다.
본 명세서에서 사용된 바와 같이, "2'-MOE 뉴클레오사이드"는 2'-MOE 당 모이어티를 포함하는 뉴클레오사이드를 의미한다.
본 명세서에서 사용된 바와 같이, "2'-OMe" 또는 "2'-O-메틸 당 모이어티"는 리보실 당 모이어티의 2'-OH기 대신에 2'-OCH3기를 의미한다. 달리 제시되지 않는 한, 2'-OMe는 β-D 입체화학 배위를 갖는다.
본 명세서에서 사용된 바와 같이, "2'-OMe 뉴클레오사이드"는 2'-OMe 당 모이어티를 포함하는 뉴클레오사이드를 의미한다.
본 명세서에 사용된 바와 같이, "2'-치환된 뉴클레오사이드"는 2'-치환된 당 모이어티를 포함하는 뉴클레오사이드를 의미한다. 본 명세서에서 사용된 바와 같이, 당 모이어티에 대한 언급에서 "2'-치환된"은 H 또는 OH 이외의 적어도 하나의 2'-치환기를 포함하는 당 모이어티를 의미한다.
본 명세서에서 사용된 바와 같이, "5-메틸 사이토신"은 5 위치에 부착된 메틸기로 변형된 사이토신을 의미한다. 5-메틸 사이토신은 변형된 핵염기이다.
본 명세서에서 사용된 바와 같이, "투여하는"은 약제학적 작용제를 대상체에게 제공하는 것을 의미한다.
본 명세서에서 사용된 바와 같이, "안티센스 활성"은 그 표적 핵산에 대한 안티센스 화합물의 혼성화로 인한 임의의 검출 가능한 그리고/또는 측정 가능한 변화를 의미한다. 특정 실시형태에서, 안티센스 활성은 안티센스 화합물의 부재 하에서 표적 핵산 수준 또는 표적 단백질 수준에 비해 그러한 표적 핵산에 의해 암호화된 표적 핵산 또는 단백질의 양 또는 발현의 감소이다.
본 명세서에서 사용된 바와 같이, "안티센스 화합물"은 적어도 하나의 안티센스 활성을 달성할 수 있는 올리고머 화합물을 의미한다.
본 명세서에서 사용된 바와 같이, 치료에 대한 언급에서 "개선하다"는 치료의 부재 하에서 동일한 증상에 비해 적어도 하나의 증상이 개선됨을 의미한다. 특정 실시형태에서, 개선은 증상의 중증도 또는 빈도의 감소 또는 발병 지연 또는 증상의 중증도 또는 빈도의 진행 둔화이다. 특정 실시형태에서, 증상 또는 특징은 발달 지연, 운동실조, 언어 장애, 수면 문제, 발작 및 EEG 이상이다.
본 명세서에 사용된 바와 같이, "이환식 뉴클레오사이드" 또는 "BNA"는 이환식 당 모이어티를 포함하는 뉴클레오사이드를 의미한다.
본 명세서에 사용된 바와 같이, "이환식 당" 또는 "이환식 당 모이어티"는 2개의 고리를 포함하는 변형된 당 모이어티를 의미하고, 여기서, 제2 고리는 원자 중 2개를 연결하는 브리지를 통해 형성되어서 이환식 구조를 형성한다. 특정 실시형태에서, 이환식 당 모이어티의 제1 고리는 퓨라노실 모이어티이다. 특정 실시형태에서, 이환식 당 모이어티는 퓨라노실 모이어티를 포함하지 않는다.
본 명세서에 사용된 바와 같이, "절단 가능한 모이어티"는 생리학적 조건 하에서, 예를 들어, 세포, 대상체 또는 인간 내부에서 절단되는 원자의 결합 또는 군을 의미한다.
본 명세서에 사용된 바와 같이, 올리고뉴클레오타이드에 대한 언급에서 "상보성"은, 올리고뉴클레오타이드 및 다른 핵산의 핵염기 서열이 반대 방향으로 정렬될 때 올리고뉴클레오타이드 또는 이의 하나 이상의 부분의 핵염기 및 표적 핵산 또는 이의 하나 이상의 부분의 핵염기의 적어도 70%가 서로 수소 결합을 할 수 있음을 의미한다. 본 명세서에서 사용된 바와 같이, 상보성 핵염기는 서로와 수소 결합을 형성할 수 있는 핵염기를 의미한다. 상보성 핵염기 쌍은 아데닌(A)과 티민(T), 아데닌(A)과 유라실(U), 사이토신(C)과 구아닌(G), 5-메틸 사이토신(mC)과 구아닌(G)을 포함한다. 상보성 올리고뉴클레오타이드 및/또는 표적 핵산은 각각의 뉴클레오사이드에서 핵염기 상보성을 가질 필요는 없다. 오히려, 일부 미스매치가 용인된다. 본 명세서에서 사용된 바와 같이, 올리고뉴클레오타이드에 대한 언급에서 "완전히 상보성" 또는 "100% 상보성"은 또 다른 올리고뉴클레오타이드 또는 2개의 올리고뉴클레오타이드 중 더 짧은 것의 각각의 핵염기에서 또는 올리고뉴클레오타이드가 동일한 길이를 가진 경우에는 각각의 뉴클레오사이드에서 표적 핵산과 상보성임을 의미한다.
본 명세서에서 사용된 바와 같이, "접합체 기"는 올리고뉴클레오타이드에 직접 또는 간접적으로 부착된 원자의 기를 의미한다. 접합체 기는 접합체 모이어티 및 접합체 모이어티를 올리고뉴클레오타이드에 부착시키는 접합체 링커를 포함한다.
본 명세서에서 사용된 바와 같이, "접합체 링커"는 접합체 모이어티를 올리고뉴클레오타이드에 연결하는 적어도 하나의 결합을 포함하는 원자의 기를 의미한다.
본 명세서에서 사용된 바와 같이, "접합체 모이어티"는 접합체 링커를 통해 올리고뉴클레오타이드에 부착된 원자의 기를 의미한다.
본 명세서에 사용된 바와 같이, 올리고뉴클레오타이드의 맥락에서 "인접한"은 뉴클레오사이드, 핵염기, 당 모이어티, 또는 서로에 바로 근접한 뉴클레오사이드간 링키지(internucleoside linkage)를 지칭한다. 예를 들어, "인접한 핵염기"는 서열에서 서로에 바로 근접한 핵염기를 의미한다.
본 명세서에서 사용된 바와 같이, "구속된(constrained) 에틸" 또는 "cEt" 또는 "cEt 변형된 당 모이어티"는 β-D 리보실 이환식 당 모이어티를 의미하며, 여기서, 이환식 당의 제2 고리는 β-D 리보실 당 모이어티의 4'-탄소 및 2'-탄소를 연결하는 브리지를 통해 형성되며, 브리지는 화학식 4'-CH(CH3)-O-2'를 가지며, 브리지의 메틸기는 S 배위로 존재한다.
본 명세서에서 사용된 바와 같이, "cEt 뉴클레오사이드"는 cEt 변형된 당을 포함하는 뉴클레오사이드를 의미한다.
본 명세서에 사용된 바와 같이, "카이럴적으로 풍부한(chirally enriched) 집단"은, 특정 카이럴 중심에서 특정 입체화학 배위를 함유하는 집단 내의 분자의 수 또는 백분율이, 특정 카이럴 중심이 입체무작위인 경우, 집단 내의 동일한 특정 카이럴 중심에서 동일한 특정 입체화학 배위를 함유하는 것으로 예상된 분자의 수 또는 백분율보다 큰, 동일한 분자식의 복수의 분자를 의미한다. 각각의 분자 내에 다수의 카이럴 중심을 갖는 카이럴적으로 풍부한 분자의 집단은 하나 이상의 입체무작위 카이럴 중심을 함유할 수 있다. 특정 실시형태에서, 분자는 변형된 올리고뉴클레오타이드이다. 특정 실시형태에서, 분자는 변형된 올리고뉴클레오타이드를 포함하는 화합물이다.
본 명세서에서 사용된 바와 같이, "갭머(gapmer)"는 하나 이상의 뉴클레오사이드를 갖는 외부 영역들 사이에 위치되어 있는, RNase H 절단을 지지하는 복수의 뉴클레오사이드를 갖는 내부 영역을 포함하는 변형된 올리고뉴클레오타이드를 의미하며, 여기서, 내부 영역을 포함하는 뉴클레오사이드는 외부 영역을 포함하는 뉴클레오사이드 또는 뉴클레오사이드와 화학적으로 구별된다. 내부 영역은 "갭(gap)"으로 지칭될 수 있으며, 외부 영역은 "윙(wing)"으로 지칭될 수 있다. 달리 나타내지 않는 한, "갭머"는 당 모티프를 지칭한다. 달리 나타내지 않는 한, 갭머의 갭의 각각의 뉴클레오사이드의 당 모이어티는 비변형된 2'-β-D-데옥시리보실 당 모이어티이다. 따라서, 용어 "MOE 갭머"는 2'-β-D-데옥시뉴클레오사이드를 포함하는 갭 및 2'-MOE 뉴클레오사이드를 포함하는 윙을 갖는 갭머를 나타낸다. 달리 나타내지 않는 한, MOE 갭머는 하나 이상의 변형된 뉴클레오사이드간 링키지 및/또는 변형된 핵염기를 포함할 수 있으며, 그러한 변형은 당 변형의 갭머 패턴을 반드시 따르는 것은 아니다.
본 명세서에서 사용된 바와 같이, "핫스팟(hotspot) 영역"은 표적 핵산의 양 또는 활성의 올리고머 화합물-매개된 감소에 대해 변형 가능한 표적 핵산 상의 다양한 핵염기이다.
본 명세서에서 사용된 바와 같이, "혼성화"는 상보성 올리고뉴클레오타이드 및/또는 핵산의 짝지움 또는 어닐링을 의미한다. 특정 기전으로 제한하고자 함은 아니지만, 가장 통상적인 혼성화 기전은 상보성 핵염기 간의 수소 결합을 포함하며, 이러한 수소 결합은 왓슨-크릭, 후그스틴 또는 역 후그스틴 수소 결합일 수 있다.
본 명세서에서 사용된 바와 같이, 용어 "뉴클레오사이드간 링키지"는 올리고뉴클레오타이드 내의 인접한 뉴클레오사이드 간의 공유 링키지이다. 본 명세서에 사용된 바와 같이, "변형된 뉴클레오사이드간 링키지"는 포스포다이에스터 뉴클레오사이드간 링키지 이외의 임의의 뉴클레오사이드간 링키지를 의미한다. "포스포로티오에이트 뉴클레오사이드간 링키지"는 포스포다이에스터 뉴클레오사이드간 링키지의 비-가교 산소 원자 중 하나가 황 원자로 대체되는 변형된 뉴클레오사이드간 링키지이다.
본 명세서에서 사용된 바와 같이, "링커-뉴클레오사이드"는 올리고뉴클레오타이드를 접합체 모이어티에 직접 또는 간접적으로 연결하는 뉴클레오사이드를 의미한다. 링커-뉴클레오사이드는 올리고머 화합물의 접합체 링커 내에 위치한다. 링커-뉴클레오사이드는 이들이 올리고뉴클레오타이드와 인접하더라도 올리고머 화합물의 올리고뉴클레오타이드 부분의 일부로 간주되지 않는다.
본 명세서에서 사용된 바와 같이, "비-이환식 변형된 당 모이어티"는 당의 2개 원자 사이에 브리지를 형성하여 제2 고리를 형성하지 않는 변형을 포함하는 변형된 당 모이어티, 예컨대, 치환기를 의미한다.
본 명세서에서 사용된 바와 같이, "미스매치" 또는 "비-상보성"은 제1 올리고뉴클레오타이드와 제2 올리고뉴클레오타이드가 정렬될 때 제2 올리고뉴클레오타이드 또는 표적 핵산의 상응하는 핵염기와 상보성이지 않은 제1 올리고뉴클레오타이드의 핵염기를 의미한다.
본 명세서에서 사용된 바와 같이, "모티프"는 올리고뉴클레오타이드 내의 비변형된 및/또는 변형된 당 모이어티, 핵염기 및/또는 뉴클레오사이드간 링키지의 패턴을 의미한다.
본 명세서에서 사용된 바와 같이, "신경유전학적 장애"는 돌연변이, 결실, 단친성 이염색체 또는 각인 결합을 포함하지만 이들로 제한되지 않는 유전 가능한 유전 인자에 의해서 유발된 신경계의 병태를 의미한다.
본 명세서에서 사용된 바와 같이, "핵염기"는 비변형된 핵염기 또는 변형된 핵염기를 의미한다. 본 명세서에 사용된 바와 같이, "비변형된 핵염기"는 아데닌(A), 티민(T), 사이토신(C), 유라실(U) 또는 구아닌(G)이다. 본 명세서에 사용된 바와 같이, "변형된 핵염기"는 적어도 하나의 비변형된 핵염기와 쌍을 지을 수 있는 비변형된 A, T, C, U 또는 G 이외의 원자의 군이다. "5-메틸 사이토신"은 변형된 핵염기이다. 만능 염기(universal base)는 5개의 비변형된 핵염기 중 어느 하나와 짝지워질 수 있는 변형된 핵염기이다. 본 명세서에서 사용된 바와 같이, "핵염기 서열"은 임의의 당 또는 뉴클레오사이드간 링키지 변형과 관계없이 표적 핵산 또는 올리고뉴클레오타이드 내의 인접한 핵염기의 순서를 의미한다.
본 명세서에서 사용된 바와 같이, "뉴클레오사이드"는 핵염기 및 당 모이어티를 포함하는 화합물을 의미한다. 핵염기 및 당 모이어티는 각각 독립적으로 비변형되거나 변형된다. 본 명세서에서 사용된 바와 같이, "변형된 뉴클레오사이드"는 변형된 핵염기 및/또는 변형된 당 모이어티를 포함하는 뉴클레오사이드를 의미한다. 변형된 뉴클레오사이드는 비염기성(abasic) 뉴클레오사이드를 포함하는데, 이것은 핵염기가 결핍되어 있다. "연결된 뉴클레오사이드"는 인접한 서열 내에 연결되어 있는 뉴클레오사이드이다(즉, 연결되는 뉴클레오사이드 사이에 어떠한 추가의 뉴클레오사이드도 존재하지 않는다).
본 명세서에서 사용된 바와 같이, "올리고머 화합물"은 올리고뉴클레오타이드 및 선택적으로 하나 이상의 추가의 특징, 예컨대, 접합체 기 또는 말단 기를 의미한다. 올리고머 화합물은 제1 올리고머 화합물과 상보성인 제2 올리고 화합물과 쌍을 이룰 수 있거나 쌍을 이룰 수 없다. "단일-가닥 올리고머 화합물"은 쌍을 이루지 않은 올리고머 화합물이다. 용어 "올리고머 듀플렉스"는 상보성 핵염기 서열을 갖는 2개의 올리고머 화합물에 의해 형성된 듀플렉스를 의미한다. 올리고머 듀플렉스의 각각의 올리고머 화합물은 "듀플렉스화된 올리고머 화합물"로 지칭될 수 있다.
본 명세서에서 사용된 바와 같이, "올리고뉴클레오타이드"는 뉴클레오사이드간 링키지를 통해 연결되는 연결된 뉴클레오사이드의 가닥을 의미하며, 여기서, 각각의 뉴클레오사이드 및 뉴클레오사이드간 링키지는 변형 또는 비변형될 수 있다. 달리 나타내지 않는 한, 올리고뉴클레오타이드는 8 내지 50개의 연결된 뉴클레오사이드로 이루어진다. 본 명세서에서 사용된 바와 같이, "변형된 올리고뉴클레오타이드"는 적어도 하나의 뉴클레오사이드 또는 뉴클레오사이드간 링키지가 변형된 올리고뉴클레오타이드를 의미한다. 본 명세서에서 사용된 바와 같이, "비변형된 올리고뉴클레오타이드"는 임의의 뉴클레오사이드 변형 또는 뉴클레오사이드간 변형을 포함하지 않는 올리고뉴클레오타이드를 의미한다.
본 명세서에서 사용된 바와 같이, "약제학적으로 허용 가능한 담체 또는 희석제"는 대상체에 투여 시 사용하기에 적합한 임의의 물질을 의미한다. 이러한 특정 담체는 약제학적 조성물이, 예를 들어, 대상체에 의한 경구 섭취를 위한 정제, 환제, 드라제, 캡슐, 액체, 겔, 시럽, 슬러리, 현탁액 및 로젠지로 제형화될 수 있게 한다. 특정 실시형태에서, 약제학적으로 허용 가능한 담체 또는 희석제는 멸균수, 멸균 식염수, 멸균 완충액 또는 멸균 인공 뇌척수액이다.
본 명세서에서 사용된 바와 같이, "약제학적으로 허용 가능한 염"은 화합물의 생리학적으로 그리고 약제학적으로 허용 가능한 염을 의미한 다. 약제학적으로 허용 가능한 염은 모 화합물의 바람직한 생물학적 활성을 유지하며, 이에 바람직하지 않은 독물학적 효과를 부여하지 않는다.
본 명세서에서 사용된 바와 같이, "약제학적 조성물"은 대상체에게 투여하기에 적합한 물질의 혼합물을 의미한다. 예를 들어, 약제학적 조성물은 올리고머 화합물 및 멸균 수용액을 포함할 수 있다. 특정 실시형태에서, 약제학적 조성물은 특정 세포주에서 자유 흡수 검정(free uptake assay)에서의 활성을 나타낸다.
본 명세서에서 사용된 바와 같이, "전구약물"은 대상체 또는 이의 세포 내에서 상이한 형태로 전환되는 신체 외부에서의 형태의 치료제를 의미한다. 전형적으로, 대상체 내에서의 전구약물의 전환은 세포 또는 조직에 존재하는 효소(예를 들어, 내인성 또는 바이러스 효소)의 작용에 의해 그리고/또는 생리학적 조건에 의해 촉진된다.
본 명세서에서 사용된 바와 같이, "양 또는 활성을 감소시키거나 저해하는", "양 또는 활성을 감소시키는" 또는 "양 또는 활성을 저해하는"은 미처리 샘플 또는 대조군 샘플에서의 전사 발현 또는 활성에 대한 전사 발현 또는 활성의 감소 또는 차단을 지칭하며, 반드시 전사 발현 또는 활성의 완전한 제거를 나타내는 것은 아니다.
본 명세서에서 사용된 바와 같이, "RNA"는 단백질을 암호화하지 않는 내인성 안티센스 전사체(예를 들어, UBE3A-ATS)를 비롯한 임의의 RNA 전사체를 의미하고, 또한 달리 명시되지 않는 한 프리-mRNA 및 성숙 mRNA를 또한 포함한다.
본 명세서에서 사용된 바와 같이, "RNAi 화합물"은, 적어도 부분적으로, RISC 또는 Ago2를 통해 작용하여 표적 핵산 및/또는 표적 핵산에 의해 암호화되는 단백질을 조절하는 안티센스 화합물을 의미한다. RNAi 화합물은 이중-가닥 siRNA, 단일-가닥 RNA(ssRNA) 및 마이크로RNA 모방체를 포함한 마이크로RNA를 포함하지만 이들로 제한되지 않는다. 특정 실시형태에서, RNAi 화합물은 표적 핵산의 양, 활성 및/또는 스플라이싱을 조절한다. 용어 RNAi 화합물은 RNase H를 통해 작용하는 안티센스 화합물을 제외한다.
본 명세서에서 사용된 바와 같이, 올리고뉴클레오타이드에 대한 언급에서 "자가-상보성"은 적어도 부분적으로 그 자신에 혼성화하는 올리고뉴클레오타이드를 의미한다.
본 명세서에서 사용된 바와 같이, "표준 세포 검정"은 실시예 1에 기재된 검정 및 이의 타당한 변형을 의미한다.
본 명세서에서 사용된 바와 같이, 동일한 분자식의 분자 집단과 관련하여 "입체무작위 카이럴 중심"은 무작위 입체화학 배위를 갖는 카이럴 중심을 의미한다. 예를 들어, 입체무작위 카이럴 중심을 포함하는 분자의 집단에서, 입체무작위 카이럴 중심의 (S) 배위를 갖는 분자의 수는 입체무작위 카이럴 중심의 (R) 배위를 갖는 분자의 수와 동일할 수 있지만 반드시 그러한 것은 아니다. 카이럴 중심의 입체화합 배위는 입체화학 배위를 제어하도록 설계되지 않은 합성 방법의 결과인 경우, 무작위인 것으로 간주된다. 특정 실시형태에서, 입체무작위 카이럴 중심은 입체무작위 포스포로티오에이트 뉴클레오사이드간 링키지이다.
본 명세서에서 사용된 바와 같이, "대상체"는 인간 또는 비-인간 동물을 의미한다.
본 명세서에서 사용된 바와 같이, "당 모이어티"는 비변형된 당 모이어티 또는 변형된 당 모이어티를 의미한다. 본 명세서에서 사용된 바와 같이, "비변형된 당 모이어티"는 RNA에서 발견되는 바와 같은 2'-OH(H) β-D-리보실 모이어티("비변형된 RNA 당 모이어티") 또는 DNA에서 발견되는 바와 같은 2'-H(H) β-D-데옥시리보실 당 모이어티("비변형된 DNA 당 모이어티")를 의미한다. 비변형된 당 모이어티는 각각 1', 3', 및 4' 위치에서 1개의 수소, 3' 위치에서 산소 및 5' 위치에서 2개의 수소를 갖는다. 본 명세서에서 사용된 바와 같이, "변형된 당 모이어티" 또는 "변형된 당"은 변형된 퓨라노실 당 모이어티 또는 당 대용체를 의미한다.
본 명세서에서 사용된 바와 같이, "당 대용체"는 핵염기를 또 다른 기, 예컨대, 올리고뉴클레오타이드의 뉴클레오사이드간 링키지, 접합체 기 또는 말단 기에 연결시킬 수 있는 퓨라노실 모이어티 이외의 것을 갖는 변형된 당 모이어티를 의미한다. 당 대용체를 포함하는 변형된 뉴클레오사이드는 올리고뉴클레오타이드 내의 하나 이상의 위치에 혼입될 수 있으며, 그러한 올리고뉴클레오타이드는 상보성 올리고머 화합물 또는 표적 핵산에 혼성화할 수 있다.
본 명세서에서 사용된 바와 같이, "증상 또는 특징"은 질환 또는 장애의 존재 또는 정도를 나타내는 임의의 물리적 특징부 또는 시험 결과를 의미한다. 특정 실시형태에서, 증상은 대상체 또는 상기 대상체를 조사하거나 시험하는 의료 전문가에게 자명하다. 특정 실시형태에서, 특징은 검시 시험(post-mortem test)을 포함하지만 이에 제한되지 않는 침습성 진단 검사 시에 자명하다.
본 명세서에서 사용된 바와 같이, "표적 핵산" 및 "표적 RNA"는 안티센스 화합물이 영향을 미치도록 설계된 핵산을 의미한다.
본 명세서에서 사용된 바와 같이, "표적 영역"은 올리고머 화합물이 혼성화되도록 설계된 표적 핵산의 일부를 의미한다.
본 명세서에서 사용된 바와 같이, "말단 기"는 올리고뉴클레오타이드의 말단에 공유적으로 연결되는 화학기 또는 원자의 기를 의미한다.
본 명세서에서 사용된 바와 같이, "치료적 유효량"은 대상체에게 치료 유익을 제공하는 약제학적 작용제의 양을 의미한다. 예를 들어, 치료적 유효량은 질환의 증상을 개선시킨다.
특정 실시형태
본 개시내용은 하기 비제한적인 넘버링된 실시형태를 제공한다:
실시형태 1. 12 내지 30개의 연결된 뉴클레오사이드로 이루어진 변형된 올리고뉴클레오타이드를 포함하는 올리고머 화합물로서, 상기 변형된 올리고뉴클레오타이드의 핵염기 서열은 UBE3A-ATS RNA의 동일한 길이 부분과 적어도 90% 상보성이고, 상기 변형된 올리고뉴클레오타이드는 변형된 당 모이어티 및 변형된 뉴클레오사이드간 링키지로부터 선택된 적어도 하나의 변형을 포함하는, 올리고머 화합물.
실시형태 2. 변형된 올리고뉴클레오타이드를 포함하는 올리고머 화합물로서, 상기 변형된 올리고뉴클레오타이드는 12 내지 30개의 연결된 뉴클레오사이드로 이루어지고, 서열번호 17 내지 2762, 2786 내지 2863, 2872 내지 2904 중 어느 것의 적어도 12, 13, 14, 15, 16, 17, 18, 19 또는 20개의 인접한 핵염기를 포함하는 핵염기 서열을 갖는, 올리고머 화합물.
실시형태 3. 변형된 올리고뉴클레오타이드를 포함하는 올리고머 화합물로서, 상기 변형된 올리고뉴클레오타이드는 12 내지 30개의 연결된 뉴클레오사이드로 이루어지고, 서열번호 2763 내지 2785 또는 2864 내지 2871 중 어느 것의 적어도 12, 13, 14, 15, 16, 17 또는 18개의 인접한 핵염기를 포함하는 핵염기 서열을 갖는, 올리고머 화합물.
실시형태 4. 변형된 올리고뉴클레오타이드를 포함하는 올리고머 화합물로서, 상기 변형된 올리고뉴클레오타이드는 12 내지 30 연결된 뉴클레오사이드로 이루어지고,
서열번호 1의 핵염기 461,413-461,487의 동일한 길이 부분;
서열번호 1의 핵염기 468,968-469,013의 동일한 길이 부분;
서열번호 1의 핵염기 483,965 내지 484,003의 동일한 길이 부분과 상보성인 적어도 8, 적어도 9, 적어도 10, 적어도 11, 적어도 12, 적어도 13, 적어도 14, 적어도 15, 적어도 16, 적어도 17, 적어도 18, 적어도 19 또는 적어도 20개의 인접한 핵염기를 포함하는 핵염기 서열을 갖는, 올리고머 화합물.
실시형태 5. 변형된 올리고뉴클레오타이드를 포함하는 올리고머 화합물로서, 상기 변형된 올리고뉴클레오타이드는 12 내지 30개의 연결된 뉴클레오사이드로 이루어지고,
서열번호 1053, 1329, 1501, 1576, 1873, 1949, 2025, 2096, 2245, 2512, 2591, 2680 내지 2682 및 2844;
서열번호 376, 377, 2751 내지 2756, 2773 내지 2776, 2872, 2873, 2876 내지 2878; 또는
서열번호 172, 764 내지 770, 995, 1445, 1668, 1743, 2255, 2595, 2762 내지 2767로부터 선택된 서열의 적어도 8, 적어도 9, 적어도 10, 적어도 11, 적어도 12, 적어도 13, 적어도 14, 적어도 15, 적어도 16, 적어도 17 또는 적어도 18개의 인접한 핵염기를 포함하는 핵염기 서열을 갖는, 올리고머 화합물.
실시형태 6. 실시형태 1 내지 5 중 어느 하나에 있어서, 상기 변형된 올리고뉴클레오타이드는 변형된 올리고뉴클레오타이드의 전체 핵염기 서열에 걸쳐서 측정되는 경우 서열번호 1, 서열번호 2915 또는 서열번호 2916의 핵염기 서열과 적어도 80%, 85%, 90%, 95% 또는 100% 상보성인 핵염기 서열을 갖는, 올리고머 화합물.
실시형태 7. 실시형태 1 내지 6 중 어느 하나에 있어서, 상기 변형된 올리고뉴클레오타이드는 적어도 하나의 변형된 뉴클레오사이드를 포함하는, 올리고머 화합물.
실시형태 8. 실시형태 7에 있어서, 상기 변형된 올리고뉴클레오타이드는 변형된 당 모이어티를 포함하는 적어도 하나의 변형된 뉴클레오사이드를 포함하는, 올리고머 화합물.
실시형태 9. 실시형태 8에 있어서, 상기 변형된 올리고뉴클레오타이드는 이환식 당 모이어티를 포함하는 적어도 하나의 변형된 뉴클레오사이드를 포함하는, 올리고머 화합물.
실시형태 10. 실시형태 9에 있어서, 상기 변형된 올리고뉴클레오타이드는 2'-4' 브리지를 갖는 이환식 당 모이어티를 포함하는 적어도 하나의 변형된 뉴클레오사이드를 포함하며, 상기 2'-4' 브리지는 -O-CH2-; 및 -O-CH(CH3)-로부터 선택되는, 올리고머 화합물.
실시형태 11. 실시형태 7 내지 10 중 어느 하나에 있어서, 상기 변형된 올리고뉴클레오타이드는 비-이환식 변형된 당 모이어티를 포함하는 적어도 하나의 변형된 뉴클레오사이드를 포함하는, 올리고머 화합물.
실시형태 12. 실시형태 11에 있어서, 상기 비-이환식 변형된 당 모이어티는 2'-MOE 변형된 당 모이어티 또는 2'-OMe 변형된 당 모이어티인, 올리고머 화합물.
실시형태 13. 실시형태 7 또는 8에 있어서, 상기 변형된 올리고뉴클레오타이드는 당 대용체(surrogate)를 포함하는 적어도 하나의 변형된 뉴클레오사이드를 포함하는, 올리고머 화합물.
실시형태 14. 실시형태 13에 있어서, 상기 변형된 올리고뉴클레오타이드는 몰폴리노 및 PNA로부터 선택된 당 대용체를 포함하는 적어도 하나의 변형된 뉴클레오사이드를 포함하는, 올리고머 화합물.
실시형태 15. 실시형태 1 내지 8 및 11 내지 14 중 어느 하나에 있어서, 상기 변형된 올리고뉴클레오타이드는 이환식 당 모이어티를 포함하지 않는, 올리고머 화합물.
실시형태 16. 실시형태 1 내지 15 중 어느 하나에 있어서, 상기 변형된 올리고뉴클레오타이드는 갭머인, 올리고머 화합물.
실시형태 17. 실시형태 1 내지 16 중 어느 하나에 있어서, 상기 변형된 올리고뉴클레오타이드는 당 모티프를 갖되, 상기 당 모티프는
1 내지 6개의 연결된 5'-영역 뉴클레오사이드로 이루어진 5'-영역;
6 내지 10개의 연결된 중심 영역 뉴클레오사이드로 이루어진 중심 영역; 및
1 내지 6개의 연결된 3'-영역 뉴클레오사이드로 이루어진 3'-영역을 포함하며;
상기 5'-영역 뉴클레오사이드 각각 및 상기 3'-영역 뉴클레오사이드 각각은 변형된 당 모이어티를 포함하고, 상기 중심 영역 뉴클레오사이드 각각은 2'-β-D-데옥시리보실 당 모이어티를 포함하는, 올리고머 화합물.
실시형태 18. 실시형태 17에 있어서, 상기 변형된 올리고뉴클레오타이드는
5개의 연결된 5'-영역 뉴클레오사이드로 이루어진 5'-영역;
10개의 연결된 중심 영역 뉴클레오사이드로 이루어진 중심 영역; 및
5개의 연결된 3'-영역 뉴클레오사이드로 이루어진 3'-영역을 가지며;
상기 5'-영역 뉴클레오사이드 각각 및 상기 3'-영역 뉴클레오사이드 각각은 2'-MOE 변형된 당 모이어티를 포함하고, 상기 중심 영역 뉴클레오사이드 각각은 2'-β-D-데옥시리보실 당 모이어티를 포함하는, 올리고머 화합물.
실시형태 19. 실시형태 17에 있어서, 상기 변형된 올리고뉴클레오타이드는
4개의 연결된 5'-영역 뉴클레오사이드로 이루어진 5'-영역;
10개의 연결된 중심 영역 뉴클레오사이드로 이루어진 중심 영역; 및
6개의 연결된 3'-영역 뉴클레오사이드로 이루어진 3'-영역을 가지며;
상기 5'-영역 뉴클레오사이드 각각 및 상기 3'-영역 뉴클레오사이드 각각은 2'-MOE 변형된 당 모이어티를 포함하고, 상기 중심 영역 뉴클레오사이드 각각은 2'-β-D-데옥시리보실 당 모이어티를 포함하는, 올리고머 화합물.
실시형태 20. 실시형태 17에 있어서, 상기 변형된 올리고뉴클레오타이드는
6개의 연결된 5'-영역 뉴클레오사이드로 이루어진 5'-영역;
10개의 연결된 중심 영역 뉴클레오사이드로 이루어진 중심 영역; 및
4개의 연결된 3'-영역 뉴클레오사이드로 이루어진 3'-영역을 가지며;
상기 5'-영역 뉴클레오사이드 각각 및 상기 3'-영역 뉴클레오사이드 각각은 2'-MOE 변형된 당 모이어티를 포함하고, 상기 중심 영역 뉴클레오사이드 각각은 2'-β-D-데옥시리보실 당 모이어티를 포함하는, 올리고머 화합물.
실시형태 21. 실시형태 17에 있어서, 상기 변형된 올리고뉴클레오타이드는
5개의 연결된 5'-영역 뉴클레오사이드로 이루어진 5'-영역;
8개의 연결된 중심 영역 뉴클레오사이드로 이루어진 중심 영역; 및
5개의 연결된 3'-영역 뉴클레오사이드로 이루어진 3'-영역을 가지며;
상기 5'-영역 뉴클레오사이드 각각 및 상기 3'-영역 뉴클레오사이드 각각은 2'-MOE 변형된 당 모이어티를 포함하고, 상기 중심 영역 뉴클레오사이드 각각은 2'-β-D-데옥시리보실 당 모이어티를 포함하는, 올리고머 화합물.
실시형태 22. 실시형태 17에 있어서, 상기 변형된 올리고뉴클레오타이드는
4개의 연결된 5'-영역 뉴클레오사이드로 이루어진 5'-영역;
8개의 연결된 중심 영역 뉴클레오사이드로 이루어진 중심 영역; 및
6개의 연결된 3'-영역 뉴클레오사이드로 이루어진 3'-영역을 가지며;
상기 5'-영역 뉴클레오사이드 각각 및 상기 3'-영역 뉴클레오사이드 각각은 2'-MOE 변형된 당 모이어티를 포함하고, 상기 중심 영역 뉴클레오사이드 각각은 2'-β-D-데옥시리보실 당 모이어티를 포함하는, 올리고머 화합물.
실시형태 23. 실시형태 17에 있어서, 상기 변형된 올리고뉴클레오타이드는
4개의 연결된 5'-영역 뉴클레오사이드로 이루어진 5'-영역;
8개의 연결된 중심 영역 뉴클레오사이드로 이루어진 중심 영역; 및
6개의 연결된 3'-영역 뉴클레오사이드로 이루어진 3'-영역을 가지며;
상기 5'-영역 뉴클레오사이드 각각 및 상기 3'-영역 뉴클레오사이드 각각은 2'-MOE 변형된 당 모이어티를 포함하고, 상기 중심 영역 뉴클레오사이드 각각은 2'-β-D-데옥시리보실 당 모이어티를 포함하는, 올리고머 화합물.
실시형태 24. 실시형태 1 내지 23 중 어느 하나에 있어서, 상기 변형된 올리고뉴클레오타이드는 적어도 하나의 변형된 뉴클레오사이드간 링키지를 포함하는, 올리고머 화합물.
실시형태 25. 실시형태 24에 있어서, 상기 변형된 올리고뉴클레오타이드의 각각의 뉴클레오사이드간 링키지는 변형된 뉴클레오사이드간 링키지인, 올리고머 화합물.
실시형태 26. 실시형태 24 또는 25에 있어서, 상기 변형된 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지인, 올리고머 화합물.
실시형태 27. 실시형태 24 또는 26에 있어서, 상기 변형된 올리고뉴클레오타이드는 적어도 하나의 포스포다이에스터 뉴클레오사이드간 링키지를 포함하는, 올리고머 화합물.
실시형태 28. 실시형태 24, 26 및 27 중 어느 하나에 있어서, 뉴클레오사이드간 링키지 각각은 포스포다이에스터 뉴클레오사이드간 링키지 또는 포스포로티오에이트 뉴클레오사이드간 링키지로부터 독립적으로 선택되는, 올리고머 화합물.
실시형태 29. 실시형태 1 내지 24, 27 및 28 중 어느 하나에 있어서, 상기 변형된 올리고뉴클레오타이드는 soooossssssssssooss, sooooossssssssssoss, soooosssssssssoss, sooosssssssssooss, sooossssssssssoooss 또는 soosssssssssoooss로부터 선택된 뉴클레오사이드간 링키지 모티프를 가지며;
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고, o = 포스포다이에스터 뉴클레오사이드간 링키지인, 올리고머 화합물.
실시형태 30. 실시형태 1 내지 29 중 어느 하나에 있어서, 상기 변형된 올리고뉴클레오타이드는 변형된 핵염기를 포함하는, 올리고머 화합물.
실시형태 31. 실시형태 30에 있어서, 상기 변형된 핵염기는 5-메틸 사이토신인, 올리고머 화합물.
실시형태 32. 실시형태 1 내지 31 중 어느 하나에 있어서, 상기 변형된 올리고뉴클레오타이드는 12 내지 30, 12 내지 22, 12 내지 20, 14 내지 18, 14 내지 20, 15 내지 17, 15 내지 25, 16 내지 20, 18 내지 22 또는 18 내지 20개의 연결된 뉴클레오사이드로 이루어지는, 올리고머 화합물.
실시형태 33. 실시형태 1 내지 32 중 어느 하나에 있어서, 상기 변형된 올리고뉴클레오타이드는 18개의 연결된 뉴클레오사이드로 이루어지는, 올리고머 화합물.
실시형태 34. 실시형태 1, 2, 4 및 6 내지 32 중 어느 하나에 있어서, 상기 변형된 올리고뉴클레오타이드는 20개의 연결된 뉴클레오사이드로 이루어지는, 올리고머 화합물.
실시형태 35. 실시형태 1 내지 34 중 어느 하나에 있어서, 상기 변형된 올리고뉴클레오타이드로 이루어진, 올리고머 화합물.
실시형태 36. 실시형태 1 내지 34 중 어느 하나에 있어서, 접합체 모이어티 및 접합체 링커를 포함하는, 접합체 기를 포함하는, 올리고머 화합물.
실시형태 37. 실시형태 36에 있어서, 상기 접합체 링커는 단일 결합으로 이루어진, 올리고머 화합물.
실시형태 38. 실시형태 36에 있어서, 상기 접합체 링커는 절단 가능한, 올리고머 화합물.
실시형태 39. 실시형태 36에 있어서, 상기 접합체 링커는 1 내지 3개의 링커-뉴클레오사이드를 포함하는, 올리고머 화합물.
실시형태 40. 실시형태 36 내지 39 중 어느 하나에 있어서, 상기 접합체 기는 상기 변형된 올리고뉴클레오타이드의 5'-단부에서 상기 변형된 올리고뉴클레오타이드에 부착되어 있는, 올리고머 화합물.
실시형태 41. 실시형태 36 내지 39 중 어느 하나에 있어서, 상기 접합체 기는 상기 변형된 올리고뉴클레오타이드의 3'-단부에서 상기 변형된 올리고뉴클레오타이드에 부착되어 있는, 올리고머 화합물.
실시형태 42. 실시형태 1 내지 34 및 36 내지 제41 중 어느 하나에 있어서, 말단 기를 포함하는, 올리고머 화합물.
실시형태 43. 실시형태 1 내지 42 중 어느 하나에 있어서, 상기 올리고머 화합물은 단일-가닥 올리고머 화합물인, 올리고머 화합물.
실시형태 44. 실시형태 1 내지 38 및 40 내지 43 중 어느 하나에 있어서, 상기 올리고머 화합물은 링커-뉴클레오사이드를 포함하지 않는, 올리고머 화합물.
실시형태 45. 실시형태 1 내지 42 및 44 중 어느 하나의 올리고머 화합물을 포함하는 올리고머 듀플렉스.
실시형태 46. 실시형태 1 내지 44 중 어느 하나의 올리고머 화합물 또는 실시형태 45의 올리고머 듀플렉스를 포함하거나 또는 이들로 이루어진, 안티센스 화합물.
실시형태 47. 실시형태 1 내지 44 중 어느 하나의 올리고머 화합물 또는 실시형태 45의 올리고머 듀플렉스 및 약제학적으로 허용 가능한 담체 또는 희석제를 포함하는, 약제학적 조성물.
실시형태 48. 실시형태 47에 있어서, 상기 약제학적으로 허용 가능한 희석제는 인공 척수액인, 약제학적 조성물.
실시형태 49. 실시형태 48에 있어서, 상기 약제학적 조성물은 상기 변형된 올리고뉴클레오타이드 및 인산염 완충 식염수로 본질적으로 이루어진, 약제학적 조성물.
실시형태 50. 대상체에게 실시형태 47 내지 50 중 어느 하나의 약제학적 조성물을 투여하는 단계를 포함하는 방법.
실시형태 51. UBE3A-ATS와 연관된 질환의 치료 방법으로서, UBE3A-ATS와 연관된 질환을 갖거나 이의 발병 위험이 있는 개체에게 치료적 유효량의 실시형태 47 내지 49 중 어느 하나의 약제학적 조성물을 투여하는 단계; 및 이에 의해서 상기 UBE3A-ATS와 연관된 질환을 치료하는 단계를 포함하는, 방법.
실시형태 52. 실시형태 51에 있어서, 상기 UBE3A-ATS-연관 질환은 안젤만 증후군인, 방법.
실시형태 53. 실시형태 50 내지 52 중 어느 하나에 있어서, 상기 UBE3A-ATS-연관 질환의 적어도 하나의 증상 또는 특징이 개선되는, 방법.
실시형태 54. 실시형태 53에 있어서, 상기 증상 또는 특징은 발달 지연, 운동실조, 언어 장애, 수면 문제, 발작 또는 EEG 이상인, 방법.
실시형태 55. 하기 화학식에 따른 변형된 올리고뉴클레오타이드 또는 이의 염:
Figure pct00001
.
실시형태 56. 하기 화학식에 따른 변형된 올리고뉴클레오타이드:
Figure pct00002
실시형태 57. 하기 화학식에 따른 변형된 올리고뉴클레오타이드 또는 이의 염:
Figure pct00003
.
실시형태 58. 하기 화학식에 따른 변형된 올리고뉴클레오타이드:
Figure pct00004
실시형태 59. 하기 화학식에 따른 변형된 올리고뉴클레오타이드 또는 이의 염:
Figure pct00005
.
실시형태 60. 하기 화학식에 상응하는 변형된 올리고뉴클레오타이드:
Figure pct00006
실시형태 61. 하기 화학식에 따른 변형된 올리고뉴클레오타이드 또는 이의 염:
Figure pct00007
.
실시형태 62. 하기 화학식에 따른 변형된 올리고뉴클레오타이드:
Figure pct00008
실시형태 63. 하기 화학식에 따른 변형된 올리고뉴클레오타이드 또는 이의 염:
Figure pct00009
.
실시형태 64. 하기 화학식에 따른 변형된 올리고뉴클레오타이드:
Figure pct00010
.
실시형태 65. 하기 화학식에 따른 변형된 올리고뉴클레오타이드 또는 이의 염:
Figure pct00011
.
실시형태 66. 하기 화학식에 따른 변형된 올리고뉴클레오타이드:
Figure pct00012
실시형태 67. 실시형태 55, 57, 59, 61, 63 및 65 중 어느 하나에 있어서, 상기 화학 구조의 나트륨염인, 변형된 올리고뉴클레오타이드.
실시형태 68. 실시형태 55 내지 67 중 어느 하나의 변형된 올리고뉴클레오타이드 및 약제학적으로 허용 가능한 담체 또는 희석제를 포함하는, 약제학적 조성물.
실시형태 69. 실시형태 68에 있어서, 상기 약제학적으로 허용 가능한 희석제는 인공 척수액인, 약제학적 조성물.
실시형태 70. 실시형태 69에 있어서, 상기 약제학적 조성물은 상기 변형된 올리고뉴클레오타이드 및 인공 척수액으로 본질적으로 이루어진, 약제학적 조성물.
실시형태 71. 하기 화학적 표기에 따른 변형된 올리고뉴클레오타이드를 포함하는, 화합물: mCesAeoTeo mCeoAeoTdsGdsAdsTds mCdsTdsTdsGdsGdsTdsAeoAeoGesGes mCe (서열번호 1949),
식 중,
A = 아데닌 핵염기이고,
mC = 5-메틸 사이토신 핵염기이며,
G = 구아닌 핵염기이고,
T = 티민 핵염기이며,
e = 2'-MOE 당 모이어티이고,
d = 2'-β-D-데옥시리보실 당 모이어티이고,
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고,
o = 포스포다이에스터 뉴클레오사이드간 링키지이다.
실시형태 72. 하기 화학적 표기에 따른 변형된 올리고뉴클레오타이드를 포함하는, 화합물: Tes mCeoAeo mCeo mCeoAeoTdsTdsTdsTdsGdsAds mCds mCdsTdsTds mCeoTesTesAe(서열번호 2751), 식 중,
A = 아데닌 핵염기이고,
mC = 5-메틸 사이토신 핵염기이며,
G = 구아닌 핵염기이고,
T = 티민 핵염기이며,
e = 2'-MOE 당 모이어티이고,
d = 2'-β-D-데옥시리보실 당 모이어티이고,
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고,
o = 포스포다이에스터 뉴클레오사이드간 링키지이다.
실시형태 73. 하기 화학적 표기에 따른 변형된 올리고뉴클레오타이드를 포함하는, 화합물: TesTeo mCeoAeo mCeo mCeoAdsTdsTdsTdsTdsGdsAds mCds mCdsTdsTeo mCesTesTe(서열번호 2752),
식 중,
A = 아데닌 핵염기이고,
mC = 5-메틸 사이토신 핵염기이며,
G = 구아닌 핵염기이고,
T = 티민 핵염기이며,
e = 2'-MOE 당 모이어티이고,
d = 2'-β-D-데옥시리보실 당 모이어티이고,
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고,
o = 포스포다이에스터 뉴클레오사이드간 링키지이다.
실시형태 74. 하기 화학적 표기에 따른 변형된 올리고뉴클레오타이드를 포함하는, 화합물: Ges mCeoAeoTeoAeo mCeo mCds mCdsAdsGdsGdsGdsTdsAdsGdsGdsAeoTesTes mCe(서열번호 765),
식 중,
A = 아데닌 핵염기이고,
mC = 5-메틸 사이토신 핵염기이며,
G = 구아닌 핵염기이고,
T = 티민 핵염기이며,
e = 2'-MOE 당 모이어티이고,
d = 2'-β-D-데옥시리보실 당 모이어티이고,
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고,
o = 포스포다이에스터 뉴클레오사이드간 링키지이다.
실시형태 75. 하기 화학적 표기에 따른 변형된 올리고뉴클레오타이드를 포함하는, 화합물: Aes mCeoGeo mCesAdsAdsTdsGdsTdsAdsTds mCdsAeoGeoGeo mCesAesAe(서열번호 2866),
식 중,
A = 아데닌 핵염기이고,
mC = 5-메틸 사이토신 핵염기이며,
G = 구아닌 핵염기이고,
T = 티민 핵염기이며,
e = 2'-MOE 당 모이어티이고,
d = 2'-β-D-데옥시리보실 당 모이어티이고,
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고,
o = 포스포다이에스터 뉴클레오사이드간 링키지이다.
실시형태 76. 하기 화학적 표기에 따른 변형된 올리고뉴클레오타이드를 포함하는, 화합물: Aes mCeo mCeoAeoTeoTdsTdsTdsGdsAds mCds mCdsTdsTds mCdsTeoTeoAesGes mCe(서열번호 2873),
식 중,
A = 아데닌 핵염기이고,
mC = 5-메틸 사이토신 핵염기이며,
G = 구아닌 핵염기이고,
T = 티민 핵염기이며,
e = 2'-MOE 당 모이어티이고,
d = 2'-β-D-데옥시리보실 당 모이어티이고,
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고,
o = 포스포다이에스터 뉴클레오사이드간 링키지이다.
실시형태 77. 실시형태 71 내지 76 중 어느 하나에 있어서, 접합체 기에 공유 연결된 상기 변형된 올리고뉴클레오타이드를 포함하는, 화합물.
실시형태 78. 실시형태 71 내지 77 중 어느 하나의 약제학적 조성물 및 약제학적으로 허용 가능한 희석제 또는 담체를 포함하는, 약제학적 조성물.
실시형태79. 실시형태 78에 있어서, 상기 약제학적으로 허용 가능한 희석제는 인공 척수액인, 약제학적 조성물.
실시형태 80. 실시형태 79에 있어서, 상기 약제학적 조성물은 상기 변형된 올리고뉴클레오타이드 및 인공 척수액으로 본질적으로 이루어진, 약제학적 조성물.
실시형태 81. 실시형태 55 내지 67 중 어느 하나의 변형된 올리고뉴클레오타이드의 카이럴적으로 풍부한 집단으로서, 상기 집단은 특정 입체화학 배위를 갖는 적어도 하나의 특정 포스포로티오에이트 뉴클레오사이드간 링키지를 포함하는 변형된 올리고뉴클레오타이드가 풍부한, 카이럴적으로 풍부한 집단.
실시형태 82. 실시형태 81에 있어서, 상기 집단은 (Sp) 배위를 갖는 적어도 하나의 특정 포스포로티오에이트 뉴클레오사이드간 링키지를 포함하는 변형된 올리고뉴클레오타이드가 풍부한, 카이럴적으로 풍부한 집단.
실시형태 83. 실시형태 81에 있어서, 상기 집단은 (Rp) 배위를 갖는 적어도 하나의 특정 포스포로티오에이트 뉴클레오사이드간 링키지를 포함하는 변형된 올리고뉴클레오타이드가 풍부한, 카이럴적으로 풍부한 집단.
실시형태 84. 실시형태 81에 있어서, 상기 집단은 각각의 포스포로티오에이트 뉴클레오사이드간 링키지에서 독립적으로 선택된 특정 입체화학 배위를 갖는 변형된 올리고뉴클레오타이드가 풍부한, 카이럴적으로 풍부한 집단.
실시형태 85. 실시형태 84에 있어서, 상기 집단은 각각의 포스포로티오에이트 뉴클레오사이드간 링키지에서 (Sp) 배위를 갖는 변형된 올리고뉴클레오타이드가 풍부한, 카이럴적으로 풍부한 집단.
실시형태 86. 실시형태 84에 있어서, 상기 집단은 각각의 포스포로티오에이트 뉴클레오사이드간 링키지에서 (Rp) 배위를 갖는 변형된 올리고뉴클레오타이드가 풍부한, 카이럴적으로 풍부한 집단.
실시형태 87. 실시형태 84에 있어서, 상기 집단은 하나의 특정 포스포로티오에이트 뉴클레오사이드간 링키지에서 (Rp) 배위를 갖고, 나머지 포스포로티오에이트 뉴클레오사이드간 링키지 각각에서 (Sp) 배위를 갖는 변형된 올리고뉴클레오타이드가 풍부한, 카이럴적으로 풍부한 집단.
실시형태 88. 실시형태 81 또는 84에 있어서, 상기 집단은 5'에서 3' 방향으로, Sp, Sp, 및 Rp 배위의 적어도 3개의 인접한 포스포로티오에이트 뉴클레오사이드간 링키지를 갖는 변형된 올리고뉴클레오타이드가 풍부한, 카이럴적으로 풍부한 집단.
실시형태 89. 실시형태 55 내지 67 중 어느 하나에 있어서, 상기 변형된 올리고뉴클레오타이드의 상기 포스포로티오에이트 뉴클레오사이드간 링키지 모두는 입체무작위인, 변형된 올리고뉴클레오타이드의 카이럴적으로 풍부한 집단.
I. 특정 올리고뉴클레오타이드
특정 실시형태에서, 본 명세서에는 연결된 뉴클레오사이드로 이루어진 올리고뉴클레오타이드를 포함하는 올리고머 화합물이 제공된다. 올리고뉴클레오타이드는 비변형된 올리고뉴클레오타이드(RNA 또는 DNA)일 수 있거나, 변형된 올리고뉴클레오타이드일 수 있다. 변형된 올리고뉴클레오타이드는 비변형된 RNA 또는 DNA에 비해 적어도 하나의 변형을 포함한다. 즉, 변형된 올리고뉴클레오타이드는 적어도 하나의 변형된 뉴클레오사이드(변형된 당 모이어티 및/또는 변형된 핵염기 포함) 및/또는 적어도 하나의 변형된 뉴클레오사이드간 링키지를 포함한다.
A. 특정 변형된 뉴클레오사이드
변형된 뉴클레오사이드는 변형된 당 모이어티 또는 변형된 핵염기 또는 변형된 당 모이어티 및 변형된 핵염기 둘 다를 포함한다.
1. 특정 당 모이어티
특정 실시형태에서, 변형된 당 모이어티는 비-이환식 변형된 당 모이어티이다. 특정 실시형태에서, 변형된 당 모이어티는 이환식 또는 삼환식 당 모이어티이다. 특정 실시형태에서, 변형된 당 모이어티는 당 대용체이다. 이러한 당 대용체는 변형된 당 모이어티의 다른 유형의 것에 상응하는 하나 이상의 치환을 포함할 수 있다.
특정 실시형태에서, 변형된 당 모이어티는 하나 이상의 치환기를 갖는 퓨라노실 고리를 포함하는 비-이환식 변형된 당 모이어티이고, 이들 치환기 중 어느 것도 이환식 구조를 형성하도록 퓨라노실 고리의 2개의 원자를 브리징하지 않는다. 이러한 비-브리징 치환기는 2', 4', 및/또는 5' 위치에서의 치환기(이들로 제한되지 않음)를 포함하는 퓨라노실의 임의의 위치에 있을 수 있다. 특정 실시형태에서, 비-이환식 변형된 당 모이어티의 하나 이상의 비-브리징 치환기는 분지형이다. 비-이환식 변형된 당 모이어티에 적합한 2'-치환기의 예는 2'-F, 2'-OCH3("OMe" 또는 "O-메틸") 및 2'-O(CH2)2OCH3 ("MOE")을 포함하지만, 이들로 제한되지 않는다. 특정 실시형태에서, 2'-치환기는 할로, 알릴, 아미노, 아지도, SH, CN, OCN, CF3, OCF3, O-C1-C10 알콕시, O-C1-C10 치환된 알콕시, O-C1-C10 알킬, O-C1-C10 치환된 알킬, S-알킬, N(Rm)-알킬, O-알켄일, S-알켄일, N(Rm)-알켄일, O-알킨일, S-알킨일, N(Rm)-알킨일, O-알킬렌일-O-알킬, 알킨일, 알크아릴, 아르알킬, O-알크아릴, O-아르알킬, O(CH2)2SCH3, O(CH2)2ON(Rm)(Rn) 또는 OCH2C(=O)-N(Rm)(Rn)(식 중, Rm 및 Rn은 각각 독립적으로, H, 아미노 보호기 또는 치환된 또는 비치환된 C1-C10 알킬임) 및 U.S. 6,531,584(Cook 등); U.S. 5,859,221(Cook 등); 및 U.S. 6,005,087(Cook 등)에 기재된 2'-치환기로부터 선택된다. 이들 2'-치환기의 특정 실시형태는 하이드록실, 아미노, 알콕시, 카복시, 벤질, 페닐, 나이트로(NO2), 티올, 티오알콕시, 티오알킬, 할로겐, 알킬, 아릴, 알켄일 및 알킨일로부터 독립적으로 선택된 하나 이상의 치환기에 의해 추가로 치환될 수 있다. 비-이환식 변형된 당 모이어티에 적합한 4'-치환기의 예는 알콕시(예를 들어, 메톡시), 알킬, 및 WO 2015/106128(Manoharan 등)에 기재된 것을 포함하지만, 이들로 제한되지 않는다. 비-이환식 변형된 당 모이어티에 적합한 5'-치환기의 예는 5-메틸(R 또는 S), 5'-바이닐 및 5'-메톡시를 포함하지만, 이들로 제한되지 않는다. 특정 실시형태에서, 비-이환식 변형된 당 모이어티는 하나 초과의 비-브리징 당 치환기, 예를 들어 2'-F-5'-메틸 당 모이어티 및 WO 2008/101157(Migawa 등) 및 US2013/0203836(Rajeev 등)에 기재된 변형된 당 모이어티 및 변형된 뉴클레오사이드를 포함한다.
특정 실시형태에서, 2'-치환된 비-이환식 변형된 뉴클레오사이드는 F, NH2, N3, OCF3, OCH3, O(CH2)3NH2, CH2CH=CH2, OCH2CH=CH2, OCH2CH2OCH3, O(CH2)2SCH3, O(CH2)2ON(Rm)(Rn), O(CH2)2O(CH2)2N(CH3)2 및 N-치환된 아세트아마이드(OCH2C(=O)-N(Rm)(Rn))(여기서, Rm 및 Rn은 각각 독립적으로 H, 아미노 보호기, 또는 치환된 또는 비치환된 C1-C10 알킬임)로부터 선택된 비-브리징 2'-치환기를 포함하는 당 모이어티를 포함한다.
특정 실시형태에서, 2'-치환된 뉴클레오사이드 비-이환식 변형된 뉴클레오사이드는 F, OCF3, OCH3, OCH2CH2OCH3, O(CH2)2SCH3, O(CH2)2ON(CH3)2, O(CH2)2O(CH2)2N(CH3)2 및 OCH2C(=O)-N(H)CH3("NMA")으로부터 선택된 비-브리징 2'-치환기를 포함하는 당 모이어티를 포함한다.
특정 실시형태에서, 2'-치환된 비-이환식 변형된 뉴클레오사이드는 F, OCH3 및 OCH2CH2OCH3로부터 선택된 비-브리징 2'-치환기를 포함하는 당 모이어티를 포함한다.
특정 변형된 당 모이어티는 퓨라노실 고리의 2개의 원자를 브리징하여 제2 고리를 형성하여, 이환식 당 모이어티를 생성시키는 치환기를 포함한다. 이러한 특정 실시형태에서, 이환식 당 모이어티는 4'와 2'의 퓨라노스 고리 원자 사이에 브리지를 포함한다. 이러한 4' 내지 2' 브리징 당 치환기의 예는 4'-CH2-2', 4'-(CH2)2-2', 4'-(CH2)3-2', 4'-CH2-O-2'("LNA"), 4'-CH2-S-2', 4'-(CH2)2-O-2' ("ENA"), 4'-CH(CH3)-O-2'("구속된 에틸" 또는 "cEt"라고 지칭됨), 4'-CH2-O-CH2-2', 4'-CH2-N(R)-2', 4'-CH(CH2OCH3)-O-2'("구속된 MOE" 또는 "cMOE") 및 이의 유사체(예를 들어, U.S. 7,399,845(Seth 등), U.S. 7,569,686(Bhat 등), U.S. 7,741,457(Swayze 등) 및 U.S. 8,022,193(Swayze 등)), 4'-C(CH3)(CH3)-O-2' 및 이의 유사체(예를 들어, U.S. 8,278,283(Seth 등)), 4'-CH2-N(OCH3)-2' 및 이의 유사체(예를 들어, U.S. 8,278,425(Prakash 등)), 4'-CH2-O-N(CH3)-2'(예를 들어, U.S. 7,696,345(Allerson 등) 및 U.S. 8,124,745(Allerson 등)), 4'-CH2-C-(H)(CH3)-2'(예를 들어, 문헌[Zhou, et al., J. Org. Chem.,2009, 74, 118-134] 참조), 4'-CH2-C-(=CH2)-2' 및 이의 유사체(예를 들어, U.S. 8,278,426(Seth 등)), 4'-C(RaRb)-N(R)-O-2', 4'-C(RaRb)-O-N(R)-2', 4'-CH2-O-N(R)-2' 및 4'-CH2-N(R)-O-2'(여기서, R, Ra 및 Rb는 각각 독립적으로 H, 보호기 또는 C1-C12 알킬임)(예를 들어, U.S. 7,427,672(Imanishi 등))을 포함하지만, 이들로 제한되지 않는다.
특정 실시형태에서, 이러한 4' 내지 2' 브리지는 독립적으로 -[C(Ra)(Rb)]n-, -[C(Ra)(Rb)]n-O-, -C(Ra)=C(Rb)-, -C(Ra)=N-, -C(=NRa)-, -C(=O)-, -C(=S)-, -O-, -Si(Ra)2-, -S(=O)x- 및 -N(Ra)-로부터 독립적으로 선택된 1개 내지 4개의 연결된 기를 포함하고;
식 중,
x는 0, 1 또는 2이고;
n은 1, 2, 3 또는 4이고;
Ra 및 Rb는 각각 독립적으로 H, 보호기, 하이드록실, C1-C12 알킬, 치환된 C1-C12 알킬, C2-C12 알켄일, 치환된 C2-C12 알켄일, C2-C12 알킨일, 치환된 C2-C12 알킨일, C5-C20 아릴, 치환된 C5-C20 아릴, 헤테로사이클 라디칼, 치환된 헤테로사이클 라디칼, 헤테로아릴, 치환된 헤테로아릴, C5-C7 지환식 라디칼, 치환된 C5-C7 지환식 라디칼, 할로겐, OJ1, NJ1J2, SJ1, N3, COOJ1, 아실(C(=O)-H), 치환된 아실, CN, 설포닐(S(=O)2-J1) 또는 설폭실(S(=O)-J1)이고;
J1 및 J2는 각각 독립적으로 H, C1-C12 알킬, 치환된 C1-C12 알킬, C2-C12 알켄일, 치환된 C2-C12 알켄일, C2-C12 알킨일, 치환된 C2-C12 알킨일, C5-C20 아릴, 치환된 C5-C20 아릴, 아실(C(=O)-H), 치환된 아실, 헤테로사이클 라디칼, 치환된 헤테로사이클 라디칼, C1-C12 아미노알킬, 치환된 C1-C12 아미노알킬 또는 보호기이다.
추가적인 이환식 당 모이어티는 당업계에 공지되어 있고, 예를 들어 문헌[Freier et al., Nucleic Acids Research, 1997, 25(22), 4429-4443, Albaek et al., J. Org. Chem., 2006, 71, 7731-7740, Singh et al., Chem. Commun., 1998, 4, 455-456; Koshkin et al., Tetrahedron, 1998, 54, 3607-3630; Kumar et al., Bioorg. Med. Chem. Lett., 1998, 8, 2219-2222; Singh et al., J. Org. Chem., 1998, 63, 10035-10039; Srivastava et al., J. Am. Chem. Soc., 2007, 129, 8362-8379]; U.S. 7,053,207(Wengel 등); U.S. 6,268,490(Imanishi 등); U.S. 6,770,748(Imanishi 등); U.S. RE44,779(Imanishi 등); U.S. 6,794,499(Wengel 등); U.S. 6,670,461(Wengel 등); U.S. 7,034,133(Wengel 등); U.S. 8,080,644(Wengel 등); U.S. 8,034,909(Wengel 등); U.S. 8,153,365(Wengel 등); U.S. 7,572,582(Wengel 등); 및 U.S. 6,525,191(Ramasamy 등); WO 2004/106356(Torsten 등); WO 1999/014226(Wengel 등); WO 2007/134181(Seth 등); U.S. 7,547,684(Seth 등); U.S. 7,666,854(Seth 등); U.S. 8,088,746(Seth 등); U.S. 7,750,131(Seth 등); U.S. 8,030,467(Seth 등); U.S. 8,268,980(Seth 등); U.S. 8,546,556(Seth 등); U.S. 8,530,640(Seth 등); U.S. 9,012,421(Migawa 등); U.S. 8,501,805(Seth 등); 및 미국 특허 공보 US 2008/0039618(Allerson 등) 및 US2015/0191727(Migawa 등)을 참조하기 바란다.
특정 실시형태에서, 이러한 이환식 당 모이어티를 도입한 이환식 당 모이어티 및 뉴클레오사이드는 이성질체 배위로 추가로 정의된다. 예를 들어, (본 명세서에 기재된) LNA 뉴클레오사이드는 α-L 배위 또는 β-D 배위일 수 있다.
Figure pct00013
α-L-메틸렌옥시(4'-CH2-O-2') 또는 α-L-LNA 이환식 뉴클레오사이드는 안티센스 활성을 나타낸 올리고뉴클레오타이드로 도입된다(문헌[Frieden et al., Nucleic Acids Research, 2003, 21, 6365-6372]). 본 명세서에서, 이환식 뉴클레오사이드의 일반적인 설명은 이성질체 배위 둘 다를 포함한다. 특정 이환식 뉴클레오사이드(예를 들어, LNA 또는 cEt)의 위치가 본 명세서에서 예시된 실시형태에서 확인될 때, 이들은, 달리 명시되지 않는 한, β-D 배위로 존재한다.
특정 실시형태에서, 변형된 당 모이어티는 하나 이상의 비-브리징 당 치환기 및 하나 이상의 브리징 당 치환기(예를 들어, 5'-치환된 및 4'-2' 브리징된 당)를 포함한다.
특정 실시형태에서, 변형된 당 모이어티는 당 대용체이다. 이러한 특정 실시형태에서, 당 모이어티의 산소 원자는 예를 들어 황, 탄소 또는 질소 원자에 의해 대체된다. 이러한 특정 실시형태에서, 이러한 변형된 당 모이어티는 또한 본 명세서에 기재된 바와 같은 브리징 및/또는 비-브리징 치환기를 포함한다. 예를 들어, 특정 당 대용체는 4'-황 원자 및 2'-위치(예를 들어, U.S. 7,875,733(Bhat 등) 및 U.S. 7,939,677(Bhat 등) 참조) 및/또는 5' 위치에서의 치환을 포함한다.
특정 실시형태에서, 당 대용체는 5개의 원자 이외를 갖는 고리를 포함한다. 예를 들어, 특정 실시형태에서, 당 대용체는 6원의 테트라하이드로피란("THP")을 포함한다. 이러한 테트라하이드로피란은 추가로 변형되거나 치환될 수 있다. 이러한 변형된 테트라하이드로피란을 포함하는 뉴클레오사이드는 헥시톨 핵산("HNA"), 아니톨 핵산("ANA"), 만니톨 핵산("MNA")(예를 들어, 문헌[Leumann, CJ. Bioorg. & Med. Chem. 2002, 10, 841-854] 참조), 플루오로 HNA:
Figure pct00014
("F-HNA", 예를 들어, U.S. 8,088,904(Swayze 등); U.S. 8,440,803(Swayze 등); U.S. 8,796,437(Swayze 등); 및 U.S. 9,005,906(Swayze 등); F-HNA는 또한 F-THP 또는 3'-플루오로 테트라하이드로피란이라 지칭될 수 있음), 및 하기 화학식을 갖는 추가적인 변형된 THP 화합물을 포함하는 뉴클레오사이드를 포함하지만, 이들로 제한되지 않는다:
Figure pct00015
(식 중, 독립적으로, 각각의 상기 변형된 THP 뉴클레오사이드의 경우:
Bx는 핵염기 모이어티이고;
T3 및 T4는 각각 독립적으로 변형된 THP 뉴클레오사이드를 올리고뉴클레오타이드의 나머지에 연결하는 뉴클레오사이드간 연결기이거나, T3 및 T4 중 하나는 변형된 THP 뉴클레오사이드를 올리고뉴클레오타이드의 나머지에 연결하는 뉴클레오사이드간 연결기이고, T3 및 T4 중 다른 하나는 H, 하이드록실 보호기, 연결된 접합체 기, 또는 5' 또는 3'-말단 기이고;
q1, q2, q3, q4, q5, q6 및 q7는 각각 독립적으로 H, C1-C6 알킬, 치환된 C1-C6 알킬, C2-C6 알켄일, 치환된 C2-C6 알켄일, C2-C6 알킨일, 또는 치환된 C2-C6 알킨일이고;
R1 및 R2는 각각 독립적으로 수소, 할로겐, 치환된 또는 비치환된 알콕시, NJ1J2, SJ1, N3, OC(=X)J1, OC(=X)NJ1J2, NJ3C(=X)NJ1J2 및 CN(여기서, X는 O, S 또는 NJ1이고, 각각의 J1, J2 및 J3은 각각 독립적으로 H 또는 C1-C6 알킬임)로부터 선택됨).
특정 실시형태에서, q1, q2, q3, q4, q5, q6 및 q7가 각각 H인 변형된 THP 뉴클레오사이드가 제공된다. 특정 실시형태에서, q1, q2, q3, q4, q5, q6 및 q7 중 적어도 하나는 H 이외이다. 특정 실시형태에서, q1, q2, q3, q4, q5, q6 및 q7 중 적어도 하나는 메틸이다. 특정 실시형태에서, R1 및 R2 중 하나가 F인 변형된 THP 뉴클레오사이드가 제공된다. 특정 실시형태에서, R1은 F이고, R2는 H이고, 특정 실시형태에서, R1은 메톡시이고, R2는 H이고, 특정 실시형태에서, R1은 메톡시에톡시이고, R2는 H이다.
특정 실시형태에서, 당 대용체는 5개 초과의 원자 및 1개 초과의 헤테로원자를 갖는 고리를 포함한다. 예를 들어, 몰폴리노 당 모이어티를 포함하는 뉴클레오사이드 및 올리고뉴클레오타이드에서의 이의 용도가 보고되어 있다(예를 들어, 문헌[Braasch et al., Biochemistry, 2002, 41, 4503-4510] 및 U.S. 5,698,685(Summerton 등); U.S. 5,166,315(Summerton 등); U.S. 5,185,444(Summerton 등); 및 U.S. 5,034,506(Summerton 등) 참조). 본 명세서에 사용된 바와 같이, 용어 "몰폴리노"는 하기 구조를 갖는 당 대용체를 의미한다:
Figure pct00016
.
특정 실시형태에서, 몰폴리노는 예를 들어 상기 몰폴리노 구조로부터 다양한 치환기를 첨가 또는 변경함으로써 변형될 수 있다. 이러한 당 대용체는 본 명세서에서 "변형된 몰폴리노"라 지칭된다.
특정 실시형태에서, 당 대용체는 비환식(acyclic) 모이어티를 포함한다. 이러한 비환식 당 대용체를 포함하는 뉴클레오사이드 및 올리고뉴클레오타이드의 예는 펩타이드 핵산("PNA"), 비환식 부틸 핵산(예를 들어, 문헌[Kumar et al., Org. Biomol. Chem., 2013, 11, 5853-5865] 참조), 및 WO2011/133876(Manoharan 등)에 기재된 뉴클레오사이드 및 올리고뉴클레오타이드를 포함하지만, 이들로 제한되지 않는다.
변형된 뉴클레오사이드에서 사용될 수 있는 많은 다른 이환식 및 삼환식 당 및 당 대용체 고리 시스템은 당업계에 공지되어 있다.
2. 특정 변형된 핵염기
특정 실시형태에서, 변형된 올리고뉴클레오타이드는 비변형된 핵염기를 포함하는 하나 이상의 뉴클레오사이드를 포함한다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 변형된 핵염기를 포함하는 하나 이상의 뉴클레오사이드를 포함한다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는, 비염기성 뉴클레오사이드라고 지칭되는, 핵염기를 포함하지 않는 하나 이상의 뉴클레오사이드를 포함한다.
특정 실시형태에서, 변형된 핵염기는 5-치환된 피리미딘, 6-아자피리미딘, 알킬 또는 알킨일 치환된 피리미딘, 알킬 치환된 퓨린, 및 N-2, N-6 및 O-6 치환된 퓨린으로부터 선택된다. 특정 실시형태에서, 변형된 핵염기는 2-아미노프로필아데닌, 5-하이드록시메틸 사이토신, 잔틴, 하이포잔틴, 2-아미노아데닌, 6-N-메틸구아닌, 6-N-메틸아데닌, 2-프로필아데닌, 2-티오유라실, 2-티오티민 및 2-티오사이토신, 5-프로핀일(-C≡C-CH3) 유라실, 5-프로핀일사이토신, 6-아조유라실, 6-아조사이토신, 6-아조티민, 5-리보실유라실(슈도유라실), 4-티오유라실, 8-할로, 8-아미노, 8-티올, 8-티오알킬, 8-하이드록실, 8-아자 및 다른 8-치환된 퓨린, 5-할로, 특히 5-브로모, 5-트라이플루오로메틸, 5-할로유라실, 및 5-할로사이토신, 7-메틸구아닌, 7-메틸아데닌, 2-F-아데닌, 2-아미노아데닌, 7-데아자구아닌, 7-데아자아데닌, 3-데아자구아닌, 3-데아자아데닌, 6-N-벤조일아데닌, 2-N-아이소부티릴구아닌, 4-N-벤조일사이토신, 4-N-벤조일유라실, 5-메틸 4-N-벤조일사이토신, 5-메틸 4-N-벤조일유라실, 만능 염기, 소수성 염기, 무차별 염기, 크기-연장된 염기 및 플루오린화 염기로부터 선택된다. 추가의 변형된 핵염기는 삼환식 피리미딘, 예컨대, 1,3-다이아자페녹사진-2-온, 1,3-다이아자페노티아진-2-온 및 9-(2-아미노에톡시)-1,3-다이아자페녹사진-2-온(G-클램프)을 포함한다. 변형된 핵염기는 퓨린 또는 피리미딘 염기가 다른 헤테로사이클에 의해 대체된 것, 예를 들어 7-데아자-아데닌, 7-데아자구아노신, 2-아미노피리딘 및 2-피리돈을 또한 포함할 수 있다. 추가의 핵염기는 U.S. 3,687,808(Merigan 등)에 개시된 것, 문헌[The Concise Encyclopedia Of Polymer Science And Engineering, Kroschwitz, J.I., Ed., John Wiley & Sons, 1990, 858-859; Englisch et al., Angewandte Chemie, International Edition, 1991, 30, 613; Sanghvi, Y.S., Chapter 15, Antisense Research and Applications, Crooke, S.T. and Lebleu, B., Eds., CRC Press, 1993, 273-288]에 개시된 것; 및 문헌[Chapters 6 및 15, Antisense Drug Technology, Crooke S.T., Ed., CRC Press, 2008, 163-166 및 442-443]에 개시된 것을 포함한다.
특정 상기 기재된 변형된 핵염기, 및 다른 변형된 핵염기의 제조를 교시하는 공보는, 제한 없이, US2003/0158403(Manoharan 등); US2003/0175906(Manoharan 등); U.S. 4,845,205(Dinh 등); U.S. 5,130,302(Spielvogel 등); U.S. 5,134,066(Rogers 등); U.S. 5,175,273(Bischofberger 등); U.S. 5,367,066(Urdea 등); U.S. 5,432,272(Benner 등); U.S. 5,434,257(Matteucci 등); U.S. 5,457,187(Gmeiner 등); U.S. 5,459,255(Cook 등); U.S. 5,484,908(Froehler 등); U.S. 5,502,177(Matteucci 등); U.S. 5,525,711(Hawkins 등); U.S. 5,552,540(Haralambidis 등); U.S. 5,587,469(Cook 등); U.S. 5,594,121(Froehler 등); U.S. 5,596,091(Switzer 등); U.S. 5,614,617(Cook 등); U.S. 5,645,985(Froehler 등); U.S. 5,681,941(Cook 등); U.S. 5,811,534(Cook 등); U.S. 5,750,692(Cook 등); U.S. 5,948,903(Cook 등); U.S. 5,587,470(Cook 등); U.S. 5,457,191(Cook 등); U.S. 5,763,588(Matteucci 등); U.S. 5,830,653(Froehler 등); U.S. 5,808,027(Cook 등); 6,166,199(Cook 등); 및 U.S. 6,005,096(Matteucci 등)을 포함한다.
3. 특정 변형된 뉴클레오사이드간 링키지
특정 실시형태에서, 변형된 올리고뉴클레오타이드의 뉴클레오사이드는 임의의 뉴클레오사이드간 링키지를 이용하여 함께 연결될 수 있다. 뉴클레오사이드간 연결기의 2개의 주요 종류는 인 원자의 존재 또는 부재에 의해 정의된다. 대표적인 인 함유 뉴클레오사이드간 링키지는 포스포다이에스터를 포함하지만, 이들로 제한되지 않으며, 이것은 포스포다이에스터 결합("P(O2)=O")(비변형된 또는 자연 발생 링키지라고도 지칭함), 포스포트라이에스터, 메틸포스포네이트, 포스포르아미데이트, 및 포스포로티오에이트("P(O2)=S") 및 포스포로다이티오에이트("HS-P=S")를 함유한다. 대표적인 인 비함유 뉴클레오사이드간 연결기는 메틸렌메틸이미노(-CH2-N(CH3)-O-CH2-), 티오다이에스터, 티오노카바메이트(-O-C(=O)(NH)-S-); 실록산(-O-SiH2-O-); 및 N,N'-다이메틸하이드라진(-CH2-N(CH3)-N(CH3)-)을 포함하지만, 이들로 제한되지 않는다. 자연 발생 포스페이트 링키지와 비교하여, 변형된 뉴클레오사이드간 링키지는 올리고뉴클레오타이드의 뉴클레아제 내성을 변경, 통상적으로 증가시키도록 이용될 수 있다. 특정 실시형태에서, 카이럴 탄소를 갖는 뉴클레오사이드간 링키지는 라세미 혼합물 또는 별개의 거울상이성질체로서 제조될 수 있다. 인 함유 및 인 비함유 뉴클레오사이드간 링키지의 제조의 방법은 당업자에게 널리 공지되어 있다.
카이럴 중심을 갖는 대표적인 뉴클레오사이드간 링키지는 알킬포스포네이트 및 포스포로티오에이트를 포함하지만, 이들로 제한되지 않는다. 카이럴 중심을 갖는 뉴클레오사이드간 링키지를 포함하는 변형된 올리고뉴클레오타이드는 특정 입체화학 배위에서 입체무작위 뉴클레오사이드간 링키지를 포함하는 변형된 올리고뉴클레오타이드의 집단으로서 또는 포스포로티오에이트 연결을 포함하는 변형된 올리고뉴클레오타이드의 집단으로서 제조될 수 있다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드의 집단은 모든 포스포로티오에이트 뉴클레오사이드간 링키지가 입체무작위인 포스포로티오에이트 뉴클레오사이드간 링키지를 포함한다. 이러한 변형된 올리고뉴클레오타이드는 각각의 포스포로티오에이트 연결의 입체화학 배위의 무작위 선택을 발생시키는 합성 방법을 이용하여 생성될 수 있다. 그럼에도 불구하고, 당업자에 의해 널리 이해되는 바와 같이 각각의 개별 올리고뉴클레오타이드 분자의 각각의 개별 포스포로티오에이트는 정의된 입체배위를 갖는다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드의 집단은 특정 독립적으로 선택된 입체화학 배위에서 하나 이상의 특정 포스포로티오에이트 뉴클레오사이드간 링키지를 포함하는 변형된 올리고뉴클레오타이드가 풍부하다 특정 실시형태에서, 특정 포스포로티오에이트 연결의 특정 배위는 집단에서 분자의 적어도 65%로 존재한다. 특정 실시형태에서, 특정 포스포로티오에이트 연결의 특정 배위는 집단에서 분자의 적어도 70%로 존재한다. 특정 실시형태에서, 특정 포스포로티오에이트 연결의 특정 배위는 집단에서 분자의 적어도 80%로 존재한다. 특정 실시형태에서, 특정 포스포로티오에이트 연결의 특정 배위는 집단에서 분자의 적어도 90%로 존재한다. 특정 실시형태에서, 특정 포스포로티오에이트 연결의 특정 배위는 집단에서 분자의 적어도 99%로 존재한다. 변형된 올리고뉴클레오타이드의 이러한 카이럴적으로 풍부한 집단은 당해 분야에 공지된 합성 방법, 예를 들어 문헌[Oka et al., JACS 125, 8307 (2003), Wan et al. Nuc. Acid. Res. 42, 13456 (2014)] 및 WO 2017/015555에 기재된 방법을 이용하여 생성될 수 있다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드의 집단은 (Sp) 배위의 적어도 하나의 표시된 포스포로티오에이트를 갖는 변형된 올리고뉴클레오타이드가 풍부하다 특정 실시형태에서, 변형된 올리고뉴클레오타이드의 집단은 (Rp) 배위의 적어도 하나의 포스포로티오에이트를 갖는 변형된 올리고뉴클레오타이드가 풍부하다 특정 실시형태에서, (Rp) 및/또는(Sp) 포스포로티오에이트를 포함하는 변형된 올리고뉴클레오타이드는 각각 하기 화학식(여기서, "B"는 핵염기를 나타냄) 중 하나 이상을 포함한다:
Figure pct00017
달리 표시되지 않는 한, 본 명세서에 기재된 변형된 올리고뉴클레오타이드의 카이럴 뉴클레오사이드간 링키지는 입체무작위 또는 특정 입체화학 배위로 존재할 수 있다.
중성 뉴클레오사이드간 링키지는, 제한 없이, 포스포트라이에스터, 메틸포스포네이트, MMI(3'-CH2-N(CH3)-O-5'), 아마이드-3(3'-CH2-C(=O)-N(H)-5'), 아마이드-4(3'-CH2-N(H)-C(=O)-5'), 폼아세탈(3'-O-CH2-O-5'), 메톡시프로필(MOP) 및 티오폼아세탈(3'-S-CH2-O-5')을 포함한다. 추가의 중성 뉴클레오사이드간 연결은 실록산(다이알킬실록산), 카복실레이트 에스터, 카복스아마이드, 설파이드, 설포네이트 에스터 및 아마이드를 포함하는 비이온성 연결을 포함한다(예를 들어, 문헌[Carbohydrate Modifications in Antisense Research; Y.S. Sanghvi and P.D. Cook, Eds., ACS Symposium Series 580; Chapters 3 및 4, 40-65] 참조). 추가의 중성 뉴클레오사이드간 링키지는 혼합된 N, O, S 및 CH2 성분 부분을 포함하는 비이온성 연결을 포함한다.
B. 특정 모티프
특정 실시형태에서, 변형된 올리고뉴클레오타이드는 변형된 당 모이어티를 포함하는 하나 이상의 변형된 뉴클레오사이드를 포함한다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 변형된 핵염기를 포함하는 하나 이상의 변형된 뉴클레오사이드를 포함한다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 하나 이상의 변형된 뉴클레오사이드간 링키지를 포함한다. 이러한 실시형태에서, 변형된 올리고뉴클레오타이드의 변형된, 비변형된, 및 다르게 변형된 당 모이어티, 핵염기, 및/또는 뉴클레오사이드간 링키지는 패턴 또는 모티프를 한정한다. 특정 실시형태에서, 당 모이어티, 핵염기, 및 뉴클레오사이드간 링키지의 패턴은 서로에 각각 독립적이다. 따라서, 변형된 올리고뉴클레오타이드는 이의 당 모티프, 핵염기 모티프 및/또는 뉴클레오사이드간 링키지 모티프에 의해 기재될 수 있다(본 명세서에 사용된 바와 같이, 핵염기 모티프는 핵염기의 서열에 독립적인 핵염기에 대한 변형을 기재한다).
1. 특정 당 모티프
특정 실시형태에서, 올리고뉴클레오타이드는 한정된 패턴 또는 당 모티프에서 올리고뉴클레오타이드 또는 이의 부분을 따라 배열된 변형된 당 및/또는 비변형된 당 모이어티의 하나 이상의 유형을 포함한다. 특정 경우에, 이러한 당 모티프는 본 명세서에 기재된 임의의 당 변형을 포함하지만, 이들로 제한되지 않는다.
특정 실시형태에서, 변형된 올리고뉴클레오타이드는 2개의 외부 영역 또는 "윙" 및 중심 또는 내부 영역 또는 "갭"에 의해 한정된 갭머 모티프를 갖는다. 갭머 모티프의 3개의 영역(5'-윙, 갭 및 3'-윙)은 뉴클레오사이드의 인접한 서열을 형성하고, 여기서 각각의 윙의 뉴클레오사이드의 당 모이어티의 적어도 일부는 갭의 뉴클레오사이드의 당 모이어티의 적어도 일부와 다르다. 구체적으로, 적어도 갭에 가장 가까운 각각의 윙(5'-윙의 3'-가장 가까운 뉴클레오사이드 및 3'-윙의 5'-가장 가까운 뉴클레오사이드)의 뉴클레오사이드의 당 모이어티는 이웃하는 갭 뉴클레오사이드의 당 모이어티와 달라서, 윙 및 갭 사이의 경계(즉, 윙/갭 접합부)를 한정한다. 특정 실시형태에서, 갭 내의 당 모이어티는 서로 동일하다. 특정 실시형태에서, 갭은 갭의 하나 이상의 다른 뉴클레오사이드의 당 모이어티와 다른 당 모이어티를 갖는 하나 이상의 뉴클레오사이드를 포함한다. 특정 실시형태에서, 2개의 윙의 당 모티프는 서로 동일하다(대칭 갭머). 특정 실시형태에서, 5'-윙의 당 모티프는 3'-윙의 당 모티프와 다르다(비대칭 갭머).
특정 실시형태에서, 갭머의 윙은 1개 내지 6개의 뉴클레오사이드를 포함한다. 특정 실시형태에서, 갭머의 각각의 윙의 각각의 뉴클레오사이드는 변형된 당 모이어티를 포함한다. 특정 실시형태에서, 갭머의 각각의 윙 중 적어도 하나의 뉴클레오사이드는 변형된 당 모이어티를 포함한다. 특정 실시형태에서, 갭머의 각각의 윙 중 적어도 2개의 뉴클레오사이드는 변형된 당 모이어티를 포함한다. 특정 실시형태에서, 갭머의 각각의 윙 중 적어도 3개의 뉴클레오사이드는 변형된 당 모이어티를 포함한다. 특정 실시형태에서, 갭머의 각각의 윙 중 적어도 4개의 뉴클레오사이드는 변형된 당 모이어티를 포함한다. 특정 실시형태에서, 갭머의 각각의 윙 중 적어도 5개의 뉴클레오사이드는 변형된 당 모이어티를 포함한다.
특정 실시형태에서, 갭머의 갭은 7개 내지 12개의 뉴클레오사이드를 포함한다. 특정 실시형태에서, 갭머의 갭의 각각의 뉴클레오사이드는 2'-β-D-데옥시리보실 당 모이어티를 포함한다. 특정 실시형태에서, 갭머의 갭 중 적어도 하나의 뉴클레오사이드는 변형된 당 모이어티를 포함한다.
특정 실시형태에서, 갭머는 데옥시 갭머이다. 특정 실시형태에서, 각각의 윙/갭 연접부의 갭 측에서의 뉴클레오사이드는 2'- 데옥시리보실 당 모이어티를 포함하고, 각각의 윙/갭 연접부의 윙 측에서의 뉴클레오사이드는 변형된 당 모이어티이다. 특정 실시형태에서, 갭의 각각의 뉴클레오사이드는 2'-β-D-데옥시리보실 당 모이어티를 포함한다. 특정 실시형태에서, 갭머의 각각의 윙의 각각의 뉴클레오사이드는 변형된 당 모이어티를 포함한다. 특정 실시형태에서, 갭의 정확히 하나의 뉴클레오사이드는 변형된 당 모이어티를 포함하고, 갭의 나머지 뉴클레오사이드 각각은 2'-β-D-데옥시리보실 당 모이어티를 포함한다.
특정 실시형태에서, 변형된 올리고뉴클레오타이드는 완전히 변형된 당 모티프를 갖는 부분을 포함하거나 이것으로 이루어진다. 이러한 실시형태에서, 변형된 올리고뉴클레오타이드의 완전히 변형된 부분의 각각의 뉴클레오사이드는 변형된 당 모이어티를 포함한다. 특정 실시형태에서, 전체 변형된 올리고뉴클레오타이드의 각각의 뉴클레오사이드는 변형된 당 모이어티를 포함한다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 완전히 변형된 당 모티프를 갖는 부분을 포함하거나 이것으로 이루어지고, 완전히 변형된 부분 내의 각각의 뉴클레오사이드는 균일하게 변형된 당 모티프라고 본 명세서에서 지칭되는 동일한 변형된 당 모이어티를 포함한다. 특정 실시형태에서, 완전히 변형된 올리고뉴클레오타이드는 균일하게 변형된 올리고뉴클레오타이드이다. 특정 실시형태에서, 균일하게 변형된 것의 각각의 뉴클레오사이드는 동일한 2'-변형을 포함한다.
여기서, 갭머의 3개의 영역의 길이(뉴클레오사이드의 수)는 하기 표기를 이용하여 제공될 수 있다: [5'-윙에서의 뉴클레오사이드의 수] - [갭에서의 뉴클레오사이드의 수] - [3'-윙에서의 뉴클레오사이드의 수]. 따라서, 3-10-3 갭머는 각각의 윙에서 3개의 연결된 뉴클레오사이드 및 갭에서 10개의 연결된 뉴클레오사이드로 이루어진다. 이러한 명명법은 특정한 변형 앞에 존재하는 경우, 그 변형은 각각의 윙의 각각의 당 모이어티에서의 변형이고, 갭 뉴클레오사이드는 2'-β-D-데옥시리보실 당 모이어티를 포함한다. 따라서, 5-10-5 MOE 갭머는 5'-윙에서 5개의 연결된 2'-MOE 뉴클레오사이드, 갭에서 10개의 연결된 2'- β-D-데옥시뉴클레오사이드 및 3'-윙에서 5개의 연결된 2'-MOE 뉴클레오사이드로 이루어진다. 3-10-3 cEt 갭머는 5'-윙에서 3개의 연결된 cEt 뉴클레오사이드, 갭에서 10개의 연결된 2'- β-D-데옥시뉴클레오사이드 및 3'-윙에서 3개의 연결된 cEt 뉴클레오사이드로 이루어진다. 5-8-5 갭머는 5'-윙에서 변형된 당 모이어티를 포함하는 5개의 연결된 뉴클레오사이드, 갭에서 8개의 연결된 2'-β-D-데옥시뉴클레오사이드 및 3'-윙에서 변형된 당 모이어티를 포함하는 5개의 연결된 뉴클레오사이드로 이루어진다. 5-8-5 혼합 갭머는 5'- 및/또는 3'-윙에 적어도 2개의 변형된 당 모이어티를 갖는다.
특정 실시형태에서, 변형된 올리고뉴클레오타이드는 5-10-5 MOE 갭머이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 4-10-6 MOE 갭머이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 6-10-4 MOE 갭머이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 5-8-5 MOE 갭머이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 6-8-4 MOE 갭머이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 4-8-6 MOE 갭머이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 X-Y-Z MOE 갭머이고, 식 중, X 및 Z는 1, 2, 3, 4, 5 또는 6으로부터 독립적으로 선택되고, Y는 7, 8, 9, 10 또는 11이다.
2. 특정 핵염기 모티프
특정 실시형태에서, 올리고뉴클레오타이드는 한정된 패턴 또는 모티프에서 올리고뉴클레오타이드 또는 이의 부분을 따라 배열된 변형된 및/또는 비변형된 핵염기를 포함한다. 특정 실시형태에서, 각각의 핵염기는 변형된다. 특정 실시형태에서, 핵염기 중 어느 것도 변형되지 않는다. 특정 실시형태에서, 각각의 퓨린 또는 각각의 피리미딘은 변형된다. 특정 실시형태에서, 각각의 아데닌은 변형된다. 특정 실시형태에서, 각각의 구아닌은 변형된다. 특정 실시형태에서, 각각의 티민은 변형된다. 특정 실시형태에서, 각각의 유라실은 변형된다. 특정 실시형태에서, 각각의 사이토신은 변형된다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드 내의 사이토신 핵염기의 일부 또는 전부는 5-메틸 사이토신이다. 특정 실시형태에서, 사이토신 핵염기의 전부는 5-메틸 사이토신이고, 변형된 올리고뉴클레오타이드의 다른 핵염기의 전부는 비변형된 핵염기이다.
특정 실시형태에서, 변형된 올리고뉴클레오타이드는 변형된 핵염기의 블록을 포함한다. 이러한 특정 실시형태에서, 블록은 올리고뉴클레오타이드의 3'-단부에 존재한다. 특정 실시형태에서, 블록은 올리고뉴클레오타이드의 3'-단부의 3개의 뉴클레오사이드 내에 존재한다. 특정 실시형태에서, 블록은 올리고뉴클레오타이드의 5'-단부에 존재한다. 특정 실시형태에서, 블록은 올리고뉴클레오타이드의 5'-단부의 3개의 뉴클레오사이드 내에 존재한다.
특정 실시형태에서, 갭머 모티프를 포함하는 올리고뉴클레오타이드는 변형된 핵염기를 포함하는 뉴클레오사이드를 포함한다. 이러한 특정 실시형태에서, 변형된 핵염기를 포함하는 1개의 뉴클레오사이드는 갭머 모티프를 갖는 올리고뉴클레오타이드의 중심 갭에 존재한다. 이러한 특정 실시형태에서, 상기 뉴클레오사이드의 당 모이어티는 2'-β-D-데옥시리보실 당 모이어티이다. 특정 실시형태에서, 변형된 핵염기는 2-티오피리미딘 및 5-프로핀피리미딘으로부터 선택된다.
3. 특정 뉴클레오사이드간 링키지 모티프
특정 실시형태에서, 올리고뉴클레오타이드는 한정된 패턴 또는 모티프에서 올리고뉴클레오타이드 또는 이의 부분을 따라 배열된 변형된 및/또는 비변형된 뉴클레오사이드간 링키지를 포함한다. 특정 실시형태에서, 각각의 뉴클레오사이드간 연결기는 포스포다이에스터 뉴클레오사이드간 링키지 (P(O2)=O)이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드의 각각의 뉴클레오사이드간 연결기는 포스포로티오에이트 뉴클레오사이드간 링키지(P(O2)=S)이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드의 각각의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지 및 포스포다이에스터 뉴클레오사이드간 링키지로부터 독립적으로 선택된다. 특정 실시형태에서, 각각의 포스포로티오에이트 뉴클레오사이드간 링키지는 입체무작위 포스포로티오에이트, (Sp) 포스포로티오에이트 및 (Rp) 포스포로티오에이트로부터 독립적으로 선택된다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드의 당 모티프는 갭머이고, 갭 내의 뉴클레오사이드간 링키지는 모두 변형된다. 이러한 특정 실시형태에서, 윙에서의 뉴클레오사이드간 링키지의 일부 또는 전부는 비변형된 포스포다이에스터 뉴클레오사이드간 링키지이다. 특정 실시형태에서, 말단 뉴클레오사이드간 링키지는 변형된다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드의 당 모티프는 갭머이고, 뉴클레오사이드간 링키지 모티프는 적어도 하나의 윙에서 적어도 하나의 포스포다이에스터 뉴클레오사이드간 링키지를 포함하고, 적어도 하나의 포스포다이에스터 연결은 말단 뉴클레오사이드간 링키지가 아니고, 나머지 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이다. 이러한 특정 실시형태에서, 포스포로티오에이트 연결의 전부는 입체무작위이다. 특정 실시형태에서, 윙에서의 포스포로티오에이트 연결의 전부는 (Sp) 포스포로티오에이트이고, 갭은 적어도 하나의 Sp, Sp, Rp 모티프를 포함한다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드의 집단은 이러한 뉴클레오사이드간 링키지 모티프를 포함하는 변형된 올리고뉴클레오타이드가 풍부하다.
특정 실시형태에서, 변형된 뉴클레오타이드는 soooossssssssssooss의 뉴클레오사이드간 링키지 모티프를 갖고, 식 중, 각각의 "s"는 포스포로티오에이트 뉴클레오사이드간 링키지를 나타내고, 각각의 "o"는 포스포다이에스터 뉴클레오사이드간 링키지를 나타낸다. 특정 실시형태에서, 변형된 뉴클레오타이드는 sooooossssssssssoss의 뉴클레오사이드간 링키지 모티프를 갖고, 식 중, 각각의 "s"는 포스포로티오에이트 뉴클레오사이드간 링키지를 나타내고, 각각의 "o"는 포스포다이에스터 뉴클레오사이드간 링키지를 나타낸다. 특정 실시형태에서, 변형된 뉴클레오타이드는 soooosssssssssoss의 뉴클레오사이드간 링키지 모티프를 갖고, 식 중, 각각의 "s"는 포스포로티오에이트 뉴클레오사이드간 링키지를 나타내고, 각각의 "o"는 포스포다이에스터 뉴클레오사이드간 링키지를 나타낸다. 특정 실시형태에서, 변형된 뉴클레오타이드는 sooosssssssssooss의 뉴클레오사이드간 링키지 모티프를 갖고, 식 중, 각각의 "s"는 포스포로티오에이트 뉴클레오사이드간 링키지를 나타내고, 각각의 "o"는 포스포다이에스터 뉴클레오사이드간 링키지를 나타낸다. 특정 실시형태에서, 변형된 뉴클레오타이드는 sooossssssssssoooss의 뉴클레오사이드간 링키지 모티프를 갖고, 식 중, 각각의 "s"는 포스포로티오에이트 뉴클레오사이드간 링키지를 나타내고, 각각의 "o"는 포스포다이에스터 뉴클레오사이드간 링키지를 나타낸다. 특정 실시형태에서, 변형된 뉴클레오타이드는 soosssssssssoooss의 뉴클레오사이드간 링키지 모티프를 갖고, 식 중, 각각의 "s"는 포스포로티오에이트 뉴클레오사이드간 링키지를 나타내고, 각각의 "o"는 포스포다이에스터 뉴클레오사이드간 링키지를 나타낸다.
C. 특정 길이
활성을 제거하지 않으면서 올리고뉴클레오타이드의 길이를 증가시키거나 감소시킬 수 있다. 예를 들어, Woolf 등의 문헌(Proc. Natl. Acad. Sci. USA 89:7305-7309, 1992)에서, 일련의 올리고뉴클레오타이드 13개 내지 25개 핵염기 길이는 난모세포 주사 모델에서 표적 RNA의 절단을 유도하는 이의 능력에 대해 시험되었다. 올리고뉴클레오타이드의 단부 근처의 8개 또는 11개의 미스매치 염기를 갖는 올리고뉴클레오타이드 25 핵염기 길이는 미스매치를 함유하지 않는 올리고뉴클레오타이드보다 더 적은 정도이긴 하지만 표적 RNA의 특이적 절단을 지시할 수 있다. 유사하게, 표적 특이적 절단은 13개의 핵염기 올리고뉴클레오타이드, 예를 들어 1개 또는 3개의 미스매치를 갖는 것을 사용하여 달성되었다.
특정 실시형태에서, 올리고뉴클레오타이드(변형된 올리고뉴클레오타이드 포함)는 길이의 임의의 다양한 범위를 가질 수 있다. 특정 실시형태에서, 올리고뉴클레오타이드는 X개 내지 Y개의 연결된 뉴클레오사이드(여기서, X는 범위에서 뉴클레오사이드의 가장 작은 수를 나타내고, Y는 범위에서 뉴클레오사이드의 가장 큰 수를 나타냄)로 이루어진다. 이러한 특정 실시형태에서, X 및 Y는 각각 독립적으로 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49 및 50으로부터 선택되고; 단 X≤Y이다. 예를 들어, 특정 실시형태에서, 올리고뉴클레오타이드는 12 내지 13, 12 내지 14, 12 내지 15, 12 내지 16, 12 내지 17, 12 내지 18, 12 내지 19, 12 내지 20, 12 내지 21, 12 내지 22, 12 내지 23, 12 내지 24, 12 내지 25, 12 내지 26, 12 내지 27, 12 내지 28, 12 내지 29, 12 내지 30, 13 내지 14, 13 내지 15, 13 내지 16, 13 내지 17, 13 내지 18, 13 내지 19, 13 내지 20, 13 내지 21, 13 내지 22, 13 내지 23, 13 내지 24, 13 내지 25, 13 내지 26, 13 내지 27, 13 내지 28, 13 내지 29, 13 내지 30, 14 내지 15, 14 내지 16, 14 내지 17, 14 내지 18, 14 내지 19, 14 내지 20, 14 내지 21, 14 내지 22, 14 내지 23, 14 내지 24, 14 내지 25, 14 내지 26, 14 내지 27, 14 내지 28, 14 내지 29, 14 내지 30, 15 내지 16, 15 내지 17, 15 내지 18, 15 내지 19, 15 내지 20, 15 내지 21, 15 내지 22, 15 내지 23, 15 내지 24, 15 내지 25, 15 내지 26, 15 내지 27, 15 내지 28, 15 내지 29, 15 내지 30, 16 내지 17, 16 내지 18, 16 내지 19, 16 내지 20, 16 내지 21, 16 내지 22, 16 내지 23, 16 내지 24, 16 내지 25, 16 내지 26, 16 내지 27, 16 내지 28, 16 내지 29, 16 내지 30, 17 내지 18, 17 내지 19, 17 내지 20, 17 내지 21, 17 내지 22, 17 내지 23, 17 내지 24, 17 내지 25, 17 내지 26, 17 내지 27, 17 내지 28, 17 내지 29, 17 내지 30, 18 내지 19, 18 내지 20, 18 내지 21, 18 내지 22, 18 내지 23, 18 내지 24, 18 내지 25, 18 내지 26, 18 내지 27, 18 내지 28, 18 내지 29, 18 내지 30, 19 내지 20, 19 내지 21, 19 내지 22, 19 내지 23, 19 내지 24, 19 내지 25, 19 내지 26, 19 내지 29, 19 내지 28, 19 내지 29, 19 내지 30, 20 내지 21, 20 내지 22, 20 내지 23, 20 내지 24, 20 내지 25, 20 내지 26, 20 내지 27, 20 내지 28, 20 내지 29, 20 내지 30, 21 내지 22, 21 내지 23, 21 내지 24, 21 내지 25, 21 내지 26, 21 내지 27, 21 내지 28, 21 내지 29, 21 내지 30, 22 내지 23, 22 내지 24, 22 내지 25, 22 내지 26, 22 내지 27, 22 내지 28, 22 내지 29, 22 내지 30, 23 내지 24, 23 내지 25, 23 내지 26, 23 내지 27, 23 내지 28, 23 내지 29, 23 내지 30, 24 내지 25, 24 내지 26, 24 내지 27, 24 내지 28, 24 내지 29, 24 내지 30, 25 내지 26, 25 내지 27, 25 내지 28, 25 내지 29, 25 내지 30, 26 내지 27, 26 내지 28, 26 내지 29, 26 내지 30, 27 내지 28, 27 내지 29, 27 내지 30, 28 내지 29, 28 내지 30, 또는 29 내지 30개의 연결된 뉴클레오사이드로 이루어진다.
D. 특정 변형된 올리고뉴클레오타이드
특정 실시형태에서, 상기 변형(당, 핵염기, 뉴클레오사이드간 링키지)은 변형된 올리고뉴클레오타이드에 도입된다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 이의 변형 모티프 및 전체 길이를 특징으로 한다. 특정 실시형태에서, 이러한 파리미터는 각각 서로 독립적이다. 따라서, 달리 표시되지 않는 한, 갭머 당 모티프를 갖는 올리고뉴클레오타이드의 각각의 뉴클레오사이드간 링키지는 변형되거나 비변형될 수 있고, 당 변형의 갭머 변형 패턴을 따르거나 따르지 않을 수 있다. 예를 들어, 당 갭머의 윙 영역 내의 뉴클레오사이드간 링키지는 서로 동일하거나 상이할 수 있고, 당 모티프의 갭 영역의 뉴클레오사이드간 링키지로부터 동일하거나 상이할 수 있다. 마찬가지로, 이러한 당 갭머 올리고뉴클레오타이드는 당 변형의 갭머 패턴과 독립적인 하나 이상의 변형된 핵염기를 포함할 수 있다. 달리 표시되지 않는 한, 모든 변형은 핵염기 서열에 독립적이다.
E. 변형된 올리고뉴클레오타이드의 특정 집단
집단의 변형된 올리고뉴클레오타이드의 전부가 동일한 분자식을 갖는 변형된 올리고뉴클레오타이드의 집단은 입체무작위 집단 또는 카이럴적으로 풍부한 집단일 수 있다. 모든 변형된 올리고뉴클레오타이드의 모든 카이럴 중심은 입체무작위 집단에서 입체무작위이다. 카이럴적으로 풍부한 집단에서, 적어도 하나의 특정 카이럴 중심은 집단의 변형된 올리고뉴클레오타이드에서 입체무작위가 아니다. 특정 실시형태에서, 카이럴적으로 풍부한 집단의 변형된 올리고뉴클레오타이드는 β-D 리보실 당 모이어티가 풍부하고, 모든 포스포로티오에이트 뉴클레오사이드간 링키지는 입체무작위이다. 특정 실시형태에서, 카이럴적으로 풍부한 집단의 변형된 올리고뉴클레오타이드는 특정 입체화학 배위에서 β-D 리보실 당 모이어티 및 적어도 하나의, 특정 포스포로티오에이트 뉴클레오사이드간 링키지 둘 다가 풍부하다.
F. 핵염기 서열
특정 실시형태에서, 올리고뉴클레오타이드(비변형된 또는 변형된 올리고뉴클레오타이드)는 이의 핵염기 서열에 의해 추가로 기재된다. 특정 실시형태에서 올리고뉴클레오타이드는 제2 올리고뉴클레오타이드 또는 확인된 기준 핵산, 예컨대, 표적 핵산에 상보성인 핵염기 서열을 갖는다. 이러한 특정 실시형태에서, 올리고뉴클레오타이드의 부분은 제2 올리고뉴클레오타이드 또는 확인된 기준 핵산, 예컨대, 표적 핵산에 상보성인 핵염기 서열을 갖는다. 특정 실시형태에서, 올리고뉴클레오타이드의 부분 또는 전체 길이의 핵염기 서열은 제2 올리고뉴클레오타이드 또는 핵산, 예컨대, 표적 핵산과 적어도 50%, 적어도 60%, 적어도 70%, 적어도 80%, 적어도 85%, 적어도 90%, 적어도 95% 또는 100% 상보성이다.
II. 특정 올리고머 화합물
특정 실시형태에서, 본 발명에는 올리고뉴클레오타이드(변형된 또는 비변형된) 및 임의로 하나 이상의 접합체 기 및/또는 말단 기로 이루어진 올리고머 화합물을 제공된다. 접합체 기는 하나 이상의 접합체 모이어티 및 접합체 모이어티를 올리고뉴클레오타이드에 연결하는 접합체 링커로 이루어진다. 접합체 기는 올리고뉴클레오타이드의 어느 한 말단 또는 양 단부에 및/또는 임의의 내부 위치에서 부착될 수 있다. 특정 실시형태에서, 접합체 기는 변형된 올리고뉴클레오타이드의 뉴클레오사이드의 2'-위치에 부착된다. 특정 실시형태에서, 올리고뉴클레오타이드의 어느 한 말단 또는 양 말단에 부착된 접합체 기는 말단 기이다. 이러한 특정 실시형태에서, 접합체 기 또는 말단 기는 올리고뉴클레오타이드의 3' 및/또는 5'-단부에서 부착된다. 이러한 특정 실시형태에서, 접합체 기(또는 말단 기)는 올리고뉴클레오타이드의 3'-단부에서 부착된다. 특정 실시형태에서, 접합체 기는 올리고뉴클레오타이드의 3'-단부의 근처에서 부착된다. 특정 실시형태에서, 접합체 기(또는 말단 기)는 올리고뉴클레오타이드의 5'-단부에서 부착된다. 특정 실시형태에서, 접합체 기는 올리고뉴클레오타이드의 5'-단부의 근처에서 부착된다.
말단 기의 예는 접합체 기, 캡핑 기, 포스페이트 모이어티, 보호기, 변형된 또는 비변형된 뉴클레오사이드, 및 독립적으로 변형된 또는 비변형된 2개 이상의 뉴클레오사이드를 포함하지만, 이들로 제한되지 않는다.
A. 특정 접합체 기
특정 실시형태에서, 올리고뉴클레오타이드는 하나 이상의 접합체 기에 공유 부착된다. 특정 실시형태에서, 접합체 기는 약력학, 약동학, 안정성, 결합, 흡수, 조직 분포, 세포 분포, 세포 흡수, 전하 및 청소율(이들로 제한되지 않음)을 포함하는 부착된 올리고뉴클레오타이드의 하나 이상의 특성을 변경시킨다. 특정 실시형태에서, 접합체 기는 부착된 올리고뉴클레오타이드, 예를 들어 올리고뉴클레오타이드의 부착이 가능하게 하는 형광단 또는 리포터 기에 새로운 특성을 부여한다. 특정 접합체 기 및 접합체 모이어티, 예를 들어 콜레스테롤 모이어티(문헌[Letsinger et al., Proc. Natl. Acad. Sci. USA, 1989, 86, 6553-6556]), 콜산(문헌[Manoharan et al., Bioorg. Med. Chem. Lett., 1994, 4, 1053-1060]), 티오에터, 예를 들어, 헥실-S-트리틸티올(문헌[Manoharan et al., Ann. N.Y. Acad. Sci., 1992, 660, 306-309; Manoharan et al., Bioorg. Med. Chem. Lett., 1993, 3, 2765-2770]), 티오콜레스테롤(문헌[Oberhauser et al., Nucl. Acids Res., 1992, 20, 533-538]), 지방족 쇄, 예를 들어 도데칸-다이올 또는 운데실 잔기(문헌[Saison-Behmoaras et al., EMBO J., 1991, 10, 1111-1118; Kabanov et al., FEBS Lett., 1990, 259, 327-330; Svinarchuk et al., Biochimie, 1993, 75, 49-54]), 인지질, 예를 들어, 다이-헥사데실-rac-글리세롤 또는 트라이에틸-암모늄 1,2-다이-O-헥사데실-rac-글리세로-3-H-포스포네이트(문헌[Manoharan et al., Tetrahedron Lett., 1995, 36, 3651-3654; Shea et al., Nucl. Acids Res., 1990, 18, 3777-3783]), 폴리아민 또는 폴리에틸렌 글리콜 쇄(문헌[Manoharan et al., Nucleosides & Nucleotides, 1995, 14, 969-973]), 또는 아다만탄 아세트산 팔미틸 모이어티(문헌[Mishra et al., Biochim. Biophys. Acta, 1995, 1264, 229-237]), 옥타데실아민 또는 헥실아미노-카보닐-옥시콜레스테롤 모이어티(문헌[Crooke et al., J. Pharmacol. Exp. Ther., 1996, 277, 923-937]), 토코페롤기(문헌[Nishina et al., Molecular Therapy Nucleic Acids, 2015, 4, e220; 및 Nishina et al., Molecular Therapy, 2008, 16, 734-740]), 또는 GalNAc 클러스터(예를 들어, WO2014/179620)가 이미 기재되어 있다.
특정 실시형태에서, 접합체 기는 C22 알킬, C20 알킬, C16 알킬, C10 알킬, C21 알킬, C19 알킬, C18 알킬, C15 알킬, C14 알킬, C13 알킬, C12 알킬, C11 알킬, C9 알킬, C8 알킬, C7 알킬, C6 알킬, C5 알킬, C22 알켄일, C20 알켄일, C16 알켄일, C10 알켄일, C21 알켄일, C19 알켄일, C18 알켄일, C15 알켄일, C14 알켄일, C13 알켄일, C12 알켄일, C11 알켄일, C9 알켄일, C8 알켄일, C7 알켄일, C6 알켄일 또는 C5 알켄일 중 임의의 것으로부터 선택될 수 있다.
특정 실시형태에서, 접합체 기는 C22 알킬, C20 알킬, C16 알킬, C10 알킬, C21 알킬, C19 알킬, C18 알킬, C15 알킬, C14 알킬, C13 알킬, C12 알킬, C11 알킬, C9 알킬, C8 알킬, C7 알킬, C6 알킬 및 C5 알킬 중 임의의 것으로부터 선택될 수 있고, 여기서 알킬 쇄는 하나 이상의 불포화 결합을 갖는다.
1. 접합체 모이어티
접합체 모이어티는, 제한 없이, 인터칼레이터(intercalator), 리포터 분자, 폴리아민, 폴리아마이드, 펩타이드, 탄수화물, 비타민 모이어티, 폴리에틸렌 글리콜, 티오에터, 폴리에터, 콜레스테롤, 티오콜레스테롤, 콜산 모이어티, 폴레이트, 지질, 인지질, 바이오틴, 페나진, 페난트리딘, 안트라퀴논, 아다만탄, 아크리딘, 플루오레세인, 로다민, 쿠마린, 형광단 및 염료를 포함한다.
특정 실시형태에서, 접합체 모이어티는 활성 약물 물질, 예를 들어 아스피린, 와파린, 페닐부타존, 이부프로펜, 수프로펜, 펜-부펜, 케토프로펜, (S)-(+)-프라노프로펜, 카르프로펜, 단실사르코신, 2,3,5-트라이아이오도벤조산, 핑골리모드, 플루페남산, 폴린산, 벤조티아디아지드, 클로로티아자이드, 다이아제핀, 인도-메티신, 바비튜레이트, 세팔로스포린, 설파 약물, 항당뇨병제, 항박테리아제 또는 항생제를 포함한다.
2. 접합체 링커
접합체 모이어티는 접합체 링커를 통해 올리고뉴클레오타이드에 부착된다. 특정 올리고머 화합물에서, 접합체 링커는 단일 화학 결합이다(즉, 접합체 모이어티는 단일 결합을 통해 올리고뉴클레오타이드에 직접적으로 부착된다). 특정 실시형태에서, 접합체 링커는 사슬 구조, 예컨대, 하이드로카빌 쇄, 또는 반복 단위, 예컨대, 에틸렌 글리콜, 뉴클레오사이드 또는 아미노산 단위의 올리고머를 포함한다.
특정 실시형태에서, 접합체 링커는 알킬, 아미노, 옥소, 아마이드, 다이설파이드, 폴리에틸렌 글리콜, 에터, 티오에터 및 하이드록실아미노로부터 선택된 하나 이상의 기를 포함한다. 이러한 특정 실시형태에서, 접합체 링커는 알킬, 아미노, 옥소, 아마이드 및 에터기로부터 선택된 기를 포함한다. 특정 실시형태에서, 접합체 링커는 알킬 및 아마이드기로부터 선택된 기를 포함한다. 특정 실시형태에서, 접합체 링커는 알킬 및 에터기로부터 선택된 기를 포함한다. 특정 실시형태에서, 접합체 링커는 적어도 하나의 인 모이어티를 포함한다. 특정 실시형태에서, 접합체 링커는 적어도 하나의 포스페이트기를 포함한다. 특정 실시형태에서, 접합체 링커는 적어도 하나의 중성 연결기를 포함한다.
특정 실시형태에서, 상기에 기재된 접합체 링커를 포함하는 접합체 링커는 이작용성 연결 모이어티, 예를 들어 모 화합물에 접합체 기를 부착하기에 유용한 것으로 당업계에 공지된 것, 예컨대, 본 명세서에 제공된 올리고뉴클레오타이드이다. 일반적으로, 이작용성 연결 모이어티는 적어도 2개의 작용기를 포함한다. 작용기의 하나는 모 화합물에서 특정 부위에 결합하도록 선택되고, 다른 것은 접합체 기에 결합하도록 선택된다. 이작용성 연결 모이어티에서 사용된 작용기의 예는 친핵성 기와 반응하기 위한 친전자체 및 친전자성 기와 반응하기 위한 친핵체를 포함하지만, 이들로 제한되지 않는다. 특정 실시형태에서, 이작용성 연결 모이어티는 아미노, 하이드록실, 카복실산, 티올, 알킬, 알켄일 및 알킨일로부터 선택된 하나 이상의 기를 포함한다.
접합체 링커의 예는 피롤리딘, 8-아미노-3,6-다이옥사옥탄산(ADO), 석신이미딜 4-(N-말레이미도메틸) 사이클로-헥산-1-카복실레이트(SMCC) 및 6-아미노헥산산(AHEX 또는 AHA)을 포함하지만, 이들로 제한되지 않는다. 다른 접합체 링커는 치환된 또는 비치환된 C1-C10 알킬, 치환된 또는 비치환된 C2-C10 알켄일 또는 치환된 또는 비치환된 C2-C10 알킨일(여기서, 바람직한 치환기의 비제한적인 목록은 하이드록실, 아미노, 알콕시, 카복시, 벤질, 페닐, 나이트로, 티올, 티오알콕시, 할로겐, 알킬, 아릴, 알켄일 및 알킨일을 포함함)을 포함하지만, 이들로 제한되지 않는다.
특정 실시형태에서, 접합체 링커는 1개 내지 10개의 링커-뉴클레오사이드를 포함한다. 특정 실시형태에서, 접합체 링커는 2개 내지 5개의 링커-뉴클레오사이드를 포함한다. 특정 실시형태에서, 접합체 링커는 정확히 3개의 링커-뉴클레오사이드를 포함한다. 특정 실시형태에서, 접합체 링커는 TCA 모티프를 포함한다. 특정 실시형태에서, 이러한 링커-뉴클레오사이드는 변형된 뉴클레오사이드이다. 특정 실시형태에서 이러한 링커-뉴클레오사이드는 변형된 당 모이어티를 포함한다. 특정 실시형태에서, 링커-뉴클레오사이드는 비변형된다. 특정 실시형태에서, 링커-뉴클레오사이드는 퓨린, 치환된 퓨린, 피리미딘 또는 치환된 피리미딘으로부터 선택된 선택적으로 보호된 복소환식 염기를 포함한다. 특정 실시형태에서, 절단 가능한 모이어티는 유라실, 티민, 사이토신, 4-N-벤조일사이토신, 5-메틸 사이토신, 4-N-벤조일-5-메틸 사이토신, 아데닌, 6-N-벤조일아데닌, 구아닌 및 2-N-아이소부티릴구아닌으로부터 선택된 뉴클레오사이드이다. 전형적으로, 링커-뉴클레오사이드가 표적 조직에 도달한 후 올리고머 화합물로부터 절단되는 것이 바람직하다. 따라서, 링커-뉴클레오사이드는 통상적으로 서로에 그리고 절단 가능한 결합을 통해 올리고머 화합물의 나머지에 연결된다. 특정 실시형태에서, 이러한 절단 가능한 결합은 포스포다이에스터 결합이다.
여기서, 링커-뉴클레오사이드는 올리고뉴클레오타이드의 일부인 것으로 생각되지 않는다. 따라서, 올리고머 화합물이 연결된 뉴클레오사이드의 기재된 수 또는 범위 및/또는 기준 핵산에 대한 기재된 상보성 백분율로 이루어진 올리고뉴클레오타이드를 포함하고, 올리고머 화합물이 또한 링커-뉴클레오사이드를 포함하는 접합체 링커를 포함하는 접합체 기를 포함하는 실시형태에서, 이러한 링커-뉴클레오사이드는 올리고뉴클레오타이드의 길이를 향해 계수되지 않고, 기준 핵산에 대한 올리고뉴클레오타이드의 상보성 백분율을 결정하는 데 사용되지 않는다. 예를 들어, 올리고머 화합물은 (1) 8개 내지 30개의 뉴클레오사이드로 이루어진 변형된 올리고뉴클레오타이드 및 (2) 변형된 올리고뉴클레오타이드의 뉴클레오사이드와 인접한 1개 내지 10개의 링커-뉴클레오사이드를 포함하는 접합체 기를 포함할 수 있다. 이러한 올리고머 화합물에서 인접한 연결된 뉴클레오사이드의 전체 수는 30개 초과이다. 대안적으로, 올리고머 화합물은 접합체 기 없이 8개 내지 30개의 뉴클레오사이드로 이루어진 변형된 올리고뉴클레오타이드를 포함할 수 있다. 이러한 올리고머 화합물에서 인접한 연결된 뉴클레오사이드의 전체 수는 30개 미만이다. 달리 표시되지 않는 한, 접합체 링커는 10개 이하의 링커-뉴클레오사이드를 포함한다. 특정 실시형태에서, 접합체 링커는 5개 이하의 링커-뉴클레오사이드를 포함한다. 특정 실시형태에서, 접합체 링커는 3개 이하의 링커-뉴클레오사이드를 포함한다. 특정 실시형태에서, 접합체 링커는 2개 이하의 링커-뉴클레오사이드를 포함한다. 특정 실시형태에서, 접합체 링커는 1개 이하의 링커-뉴클레오사이드를 포함한다.
특정 실시형태에서, 접합체 기가 올리고뉴클레오타이드로부터 절단되는 것이 바람직하다. 예를 들어, 특정 상황에서, 특정 접합체 모이어티를 포함하는 올리고머 화합물은 특정 세포 유형에 의해 더 양호하게 흡수되지만, 올리고머 화합물이 흡수되면, 절단된 접합체 기가 비접합된 또는 모 올리고뉴클레오타이드를 방출하는 것이 바람직하다. 따라서, 특정 접합체 링커는 하나 이상의 절단 가능한 모이어티를 포함할 수 있다. 특정 실시형태에서, 절단 가능한 모이어티는 절단 가능한 결합이다. 특정 실시형태에서, 절단 가능한 모이어티는 적어도 하나의 절단 가능한 결합을 포함하는 원자의 기이다. 특정 실시형태에서, 절단 가능한 모이어티는 1개, 2개, 3개, 4개 또는 4개 초과의 절단 가능한 결합을 갖는 원자의 기를 포함한다. 　 특정 실시형태에서, 절단 가능한 모이어티는 세포 또는 세포하 구획, 예컨대, 리소좀 내에서 선택적으로 절단된다. 특정 실시형태에서, 절단 가능한 모이어티는 내인성 효소, 예컨대, 뉴클레아제에 의해 선택적으로 절단된다.
특정 실시형태에서, 절단 가능한 결합은 아마이드, 에스터, 에터, 포스포다이에스터의 에스터 중 하나 또는 둘 다, 포스페이트 에스터, 카바메이트 또는 다이설파이드로부터 선택된다. 특정 실시형태에서, 절단 가능한 결합은 포스포다이에스터의 에스터 중 하나 또는 둘 다이다. 특정 실시형태에서, 절단 가능한 모이어티는 포스페이트 또는 포스포다이에스터를 포함한다. 특정 실시형태에서, 절단 가능한 모이어티는 올리고뉴클레오타이드와 접합체 모이어티 또는 접합체 기 사이의 포스페이트 또는 포스포다이에스터 링키지이다.
특정 실시형태에서, 절단 가능한 모이어티는 하나 이상의 링커-뉴클레오사이드를 포함하거나 이것으로 이루어진다. 이러한 특정 실시형태에서, 하나 이상의 링커-뉴클레오사이드는 서로에 및/또는 절단 가능한 결합을 통해 올리고머 화합물의 나머지에 연결된다. 특정 실시형태에서, 이러한 절단 가능한 결합은 비변형된 포스포다이에스터 결합이다. 특정 실시형태에서, 절단 가능한 모이어티는 포스포다이에스터 뉴클레오사이드간 링키지에 의해 올리고뉴클레오타이드의 3' 또는 5'-말단 뉴클레오사이드에 부착되고, 포스페이트 또는 포스포로티오에이트 연결에 의해 접합체 링커 또는 접합체 모이어티의 나머지에 공유 부착된 2'-데옥시 뉴클레오사이드이다. 이러한 특정 실시형태에서, 절단 가능한 모이어티는 2'-데옥시아데노신이다.
3. 세포-표적화 모이어티
특정 실시형태에서, 접합체 기는 세포-표적화 모이어티를 포함한다. 특정 실시형태에서, 접합체 기는 하기 일반 화학식을 갖는다:
Figure pct00018
식 중, n은 1 내지 약 3이고, n이 1인 경우 m은 0이고, n이 2 이상인 경우 m은 1이고, j는 1 또는 0이고, k는 1 또는 0이다.
특정 실시형태에서, n은 1이고, j는 1이며, k는 0이다. 특정 실시형태에서, n은 1이고, j는 0이며, k는 1이다. 특정 실시형태에서, n은 1이고, j는 1이며, k는 1이다. 특정 실시형태에서, n은 2이고, j는 1이며, k는 0이다. 특정 실시형태에서, n은 2이고, j는 0이며, k는 1이다. 특정 실시형태에서, n은 2이고, j는 1이며, k는 1이다. 특정 실시형태에서, n은 3이고, j는 1이며, k는 0이다. 특정 실시형태에서, n은 3이고, j는 0이며, k는 1이다. 특정 실시형태에서, n은 3이고, j는 1이며, k는 1이다.
특정 실시형태에서, 접합체 기는 적어도 하나의 테더링된 리간드를 갖는 세포-표적화 모이어티를 포함한다. 특정 실시형태에서, 세포-표적화 모이어티는 분지기에 공유 부착된 2개의 테더링된 리간드를 포함한다. 특정 실시형태에서, 세포-표적화 모이어티는 분지기에 공유 부착된 3개의 테더링된 리간드를 포함한다.
B. 특정 말단 기
특정 실시형태에서, 올리고머 화합물은 하나 이상의 말단 기를 포함한다. 이러한 특정 실시형태에서, 올리고머 화합물은 안정화된 5'-포스페이트를 포함한다. 안정화된 5'-포스페이트는 5'-포스포네이트, 예를 들어 5'-바이닐포스포네이트(이들로 제한되지 않음)를 포함하지만, 이들로 제한되지 않는다. 특정 실시형태에서, 말단 기는 하나 이상의 비염기성 뉴클레오사이드 및/또는 역전(inverted) 뉴클레오사이드를 포함한다. 특정 실시형태에서, 말단 기는 하나 이상의 2'-연결된 뉴클레오사이드를 포함한다. 이러한 특정 실시형태에서, 2'-연결된 뉴클레오사이드는 비염기성 뉴클레오사이드이다.
III. 올리고머 듀플렉스
특정 실시형태에서, 본 명세서에 기재된 올리고머 화합물은 표적 핵산의 것에 상보성인 핵염기 서열을 갖는 올리고뉴클레오타이드를 포함한다. 특정 실시형태에서, 올리고머 화합물은 제2 올리고머 화합물과 짝을 이루어 올리고머 듀플렉스를 형성한다. 이러한 올리고머 듀플렉스는 표적 핵산에 상보성인 부분을 갖는 제1 올리고머 화합물 및 제1 올리고머 화합물에 상보성인 부분을 갖는 제2 올리고머 화합물을 포함한다. 특정 실시형태에서, 올리고머 듀플렉스의 제1 올리고머 화합물은 (1) 변형된 또는 비변형된 올리고뉴클레오타이드 및 임의로 접합체 기 및 (2) 제2 변형된 또는 비변형된 올리고뉴클레오타이드 및 임의로 접합체 기를 포함하거나, 이들로 이루어진다. 올리고머 듀플렉스의 올리고머 화합물 중 어느 하나 또는 둘 다는 접합체 기를 포함할 수 있다. 올리고머 듀플렉스의 각각의 올리고머 화합물의 올리고뉴클레오타이드는 비상보성 오버행잉(overhanging) 뉴클레오사이드를 포함할 수 있다.
IV. 안티센스 활성
특정 실시형태에서, 올리고머 화합물 및 올리고머 듀플렉스는 표적 핵산에 혼성화하여서, 적어도 하나의 안티센스 활성을 발생시킬 수 있고; 이러한 올리고머 화합물 및 올리고머 듀플렉스는 안티센스 화합물이다. 특정 실시형태에서, 안티센스 화합물은 표준 세포 검정에서 표적 핵산의 양 또는 활성을 25% 이상만큼 감소시키거나 저해할 때 안티센스 활성을 갖는다. 특정 실시형태에서, 안티센스 화합물은 하나 이상의 표적 핵산에 선택적으로 영향을 미친다. 이러한 안티센스 화합물은 하나 이상의 표적 핵산에 혼성화하여서, 하나 이상의 원하는 안티센스 활성을 발생시키거나, 하나 이상의 비표적 핵산에 혼성화하지 않거나, 상당한 원치 않는 안티센스 활성을 발생시키는 방식으로 하나 이상의 비표적 핵산에 혼성화하지 않는 핵염기 서열을 포함한다.
특정 안티센스 활성에서, 표적 핵산에 대한 안티센스 화합물의 혼성화는 표적 핵산을 절단하는 단백질의 동원을 발생시킨다. 예를 들어, 특정 안티센스 화합물은 표적 핵산의 RNase H 매개된 절단을 발생시킨다. RNase H는 RNA:DNA 듀플렉스의 RNA 가닥을 절단시키는 세포 엔도뉴클레아제이다. 이러한 RNA:DNA 듀플렉스에서의 DNA는 비변형된 DNA일 필요는 없다. 특정 실시형태에서, RNase H 활성을 유발하도록 충분히 "DNA 유사한" 안티센스 화합물이 본 명세서에 기재된다. 특정 실시형태에서, 갭머의 갭에서 하나 이상의 비-DNA-유사 뉴클레오사이드가 허용된다.
특정 안티센스 활성에서, 안티센스 화합물 또는 안티센스 화합물의 일부는 RNA 유도된 슬라이싱 복합체(RNA-induced silencing complex: RISC)로 로딩되어서, 궁극적으로 표적 핵산을 절단시킨다. 예를 들어, 특정 안티센스 화합물은 Argonaute에 의한 표적 핵산의 절단을 발생시킨다. RISC로 로딩된 안티센스 화합물은 RNAi 화합물이다. RNAi 화합물은 이중 가닥(siRNA) 또는 단일 가닥(ssRNA)일 수 있다.
특정 실시형태에서, 표적 핵산에 대한 안티센스 화합물의 혼성화는 표적 핵산을 절단하는 단백질의 동원을 발생시키지 않는다. 특정 실시형태에서, 표적 핵산에 대한 안티센스 화합물의 혼성화는 표적 핵산의 스플라이싱의 변경을 발생시킨다. 특정 실시형태에서, 표적 핵산에 대한 안티센스 화합물의 혼성화는 표적 핵산과 단백질 또는 다른 핵산 사이의 결합 상호작용의 저해를 발생시킨다. 특정 실시형태에서, 표적 핵산에 대한 안티센스 화합물의 혼성화는 표적 핵산의 번역을 변경을 발생시킨다.
안티센스 활성은 직접적으로 또는 간접적으로 관찰될 수 있다. 특정 실시형태에서, 안티센스 활성의 관찰 또는 검출은 이러한 표적 핵산에 의해 암호화된 표적 핵산 또는 단백질의 양의 변화, 핵산 또는 단백질의 스플라이스 변이체의 비율의 변화 및/또는 세포 또는 대상체에서의 표현형 변화의 관찰 또는 검출을 수반한다.
V. 특정 표적 핵산
특정 실시형태에서, 올리고머 화합물은 표적 핵산에 상보성인 부분을 포함하는 올리고뉴클레오타이드를 포함하거나 이것으로 이루어진다. 특정 실시형태에서, 표적 핵산은 내인성 RNA 분자이다. 특정 실시형태에서, 표적 핵산은 단백질을 암호화한다. 이러한 특정 실시형태에서, 표적 핵산은 단백질을 암호화하지 않는 내인성 안티센스 전사체(예를 들어, UBE3A-ATS), 성숙 mRNA 및 프리-mRNA, 예를 들어 인트론, 엑손 및 비번역된 영역으로부터 선택된다. 특정 실시형태에서, 표적 RNA는 안티센스 전사체이다. 특정 실시형태에서, 표적 RNA는 성숙 mRNA이다. 특정 실시형태에서, 표적 핵산은 프리-mRNA이다. 이러한 특정 실시형태에서, 표적 영역은 전부 인트론 내에 존재한다. 특정 실시형태에서, 표적 영역은 인트론/엑손 접합부에 걸쳐있다. 특정 실시형태에서, 표적 영역은 인트론 내에 적어도 50%에 존재한다. 특정 실시형태에서, 표적 핵산은 레트로겐(retrogene)의 RNA 전사 산물이다. 특정 실시형태에서, 표적 핵산은 비-암호 RNA이다. 이러한 특정 실시형태에서, 표적 비-암호 RNA는 긴 비-암호 RNA, 짧은 비-암호 RNA, 인트론 RNA 분자로부터 선택된다.
A. 표적 핵산에 대한 상보성/미스매치
활성을 제거하지 않으면서 미스매치 염기를 도입할 수 있다. 예를 들어, Gautschi 등(문헌[J. Natl. Cancer Inst. 93:463-471, March 2001])은 시험관내 및 생체내에서 bcl-2 및 bcl-xL 둘 다의 발현을 감소시키는, bcl-2 mRNA와 100% 상보성을 갖고, bcl-xL mRNA에 대해 3개의 미스매치를 갖는 올리고뉴클레오타이드의 능력을 입증하였다. 더욱이, 이 올리고뉴클레오타이드는 생체내에서 강력한 항-종양 활성을 나타내었다. Maher 및 Dolnick(문헌[Nuc. Acid. Res. 16:3341-3358, 1988])는 토끼 망상적혈구 검정에서 인간 DHFR의 번역을 막는 이의 능력에 대해 각각 일련의 탠덤 14개의 핵염기 올리고뉴클레오타이드, 및 2개 또는 3개의 탠덤 올리고뉴클레오타이드의 서열로 이루어진 28개 및 42개의 핵염기 올리고뉴클레오타이드를 시험하였다. 3개의 14개 핵염기 올리고뉴클레오타이드는 각각 단독으로 28개 또는 42개의 핵염기 올리고뉴클레오타이드보다 더 적당한 수준이긴 하지만, 번역을 저해할 수 있었다.
특정 실시형태에서, 올리고뉴클레오타이드는 올리고뉴클레오타이드의 전체 길이에 걸쳐 표적 핵산과 상보성이다. 특정 실시형태에서, 올리고뉴클레오타이드는 표적 핵산과 99%, 95%, 90%, 85% 또는 80% 상보성이다. 특정 실시형태에서, 올리고뉴클레오타이드는 올리고뉴클레오타이드의 전체 길이에 걸쳐 표적 핵산과 적어도 80% 상보성이고, 표적 핵산에 100% 또는 전부 상보성인 부분을 포함한다. 특정 실시형태에서, 완전 상보성의 부분은 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23 또는 24개 핵염기 길이이다.
특정 실시형태에서, 올리고뉴클레오타이드는 표적 핵산에 대해 하나 이상의 미스매칭된 핵염기를 포함한다. 특정 실시형태에서, 표적에 대한 안티센스 활성은 이러한 미스매치에 의해 감소하지만, 비표적에 대한 활성은 더 높은 양만큼 감소한다. 따라서, 특정 실시형태에서, 올리고뉴클레오타이드의 선택성이 개선된다. 특정 실시형태에서, 미스매치는 갭머 모티프를 갖는 올리고뉴클레오타이드 내에 특이적으로 배치된다. 특정 실시형태에서, 미스매치는 갭 영역의 5'-단부로부터 1, 2, 3, 4, 5, 6, 7 또는 8 위치에 존재한다. 특정 실시형태에서, 미스매치는 갭 영역의 3'-단부로부터 9, 8, 7, 6, 5, 4, 3, 2, 1 위치에 존재한다. 특정 실시형태에서, 미스매치는 윙 영역의 5'-단부로부터 1, 2, 3 또는 4 위치에 존재한다. 특정 실시형태에서, 미스매치는 윙 영역의 3' 단부로부터 4, 3, 2 또는 1 위치에 존재한다.
B. UBE3A-ATS
특정 실시형태에서, 올리고머 화합물은 표적 핵산과 상보성인 올리고뉴클레오타이드 또는 이의 부분을 포함하거나 이것으로 이루어지고, 여기서 표적 핵산은 UBE3A-ATS이다. 특정 실시형태에서, UBE3A-ATS 핵산은 서열번호 1(진뱅크 수탁 번호 NC_000015.10_TRUNC_24821647_25441028), 서열번호 2915(인젬블(Ensemble) Gene ID ENSG00000224078) 또는 서열번호 2916(인젬블 전사체 ENST00000554726.1의 cDNA)에 제시된 서열을 갖는다.
특정 실시형태에서, 서열번호 1, 서열번호 2915 또는 서열번호 2916과 상보성인 올리고머 화합물은 세포에서 UBE3A-ATS를 감소시킬 수 있다. 특정 실시형태에서, 서열번호 1과 상보성인 올리고머 화합물은 세포에서 UBE3A RNA 또는 단백질을 증가시킬 수 있다. 특정 실시형태에서, 서열번호 1, 서열번호 2915 또는 서열번호 2916과 상보성인 올리고머 화합물은 세포에서 부계 UBE3A RNA 또는 단백질을 증가시킬 수 있다. 특정 실시형태에서, 세포는 시험관내에 존재한다. 특정 실시형태에서, 세포는 대상체에 존재한다. 특정 실시형태에서, 올리고머 화합물은 변형된 올리고뉴클레오타이드로 이루어진다. 특정 실시형태에서, 서열번호 1, 서열번호 2915 또는 서열번호 2916과 상보성인 올리고머 화합물은 대상체에게 투여되는 경우 신경유전학적 장애의 하나 이상의 증상 또는 특징을 개선할 수 있다. 특정 실시형태에서, 신경유전학적 장애는 AS이다. 특정 실시형태에서, 증상 또는 특징은 발달 지연, 운동실조, 언어 장애, 수면 문제, 발작 및 EEG 이상으로부터 선택된다.
특정 실시형태에서, 서열번호 1, 서열번호 2915 또는 서열번호 2916과 상보성인 올리고머 화합물은 시험관내에서 UBE3A-ATS RNA의 검출 가능한 양을 적어도 10%, 적어도 20%, 적어도 30%, 적어도 40%, 적어도 50%, 적어도 60%, 적어도 70%, 적어도 80% 또는 적어도 90%만큼 감소시킬 수 있다. 특정 실시형태에서, 서열번호 1, 서열번호 2915 또는 서열번호 2916과 상보성인 올리고머 화합물은 시험관내에서 UBE3A 단백질의 검출 가능한 양을 적어도 10%, 적어도 20%, 적어도 30%, 적어도 40%, 적어도 50%, 적어도 60%, 적어도 70%, 적어도 80% 또는 적어도 90%만큼 증가시킬 수 있다. 특정 실시형태에서, 서열번호 1, 서열번호 2915 또는 서열번호 2916과 상보성인 올리고머 화합물은 대상체의 CSF에서 UBE3A-ATS RNA의 검출 가능한 양을 적어도 10%, 적어도 20%, 적어도 30%, 적어도 40%, 적어도 50%, 적어도 60%, 적어도 70%, 적어도 80% 또는 적어도 90%만큼 감소시킬 수 있다. 특정 실시형태에서, 서열번호 1, 서열번호 2915 또는 서열번호 2916과 상보성인 올리고머 화합물은 대상체의 CSF에서 UBE3A 단백질의 검출 가능한 양을 적어도 10%, 적어도 20%, 적어도 30%, 적어도 40%, 적어도 50%, 적어도 60%, 적어도 70%, 적어도 80% 또는 적어도 90%만큼 증가시킬 수 있다.
C. 특정 조직에서의 특정 표적 핵산
특정 실시형태에서, 올리고머 화합물은 표적 핵산과 상보성인 부분을 포함하는 올리고뉴클레오타이드를 포함하거나 이것으로 이루어지고, 여기서 표적 핵산은 약리학적으로 관련된 조직에서 발현된다. 특정 실시형태에서, 약리학적으로 관련된 조직은 중치신경계를 포함하는 조직 및 세포이다. 이러한 조직은 피질, 해마 및 척수를 포함한다.
VI. 특정 약제학적 조성물
특정 실시형태에서, 본 명세서에는 1종 이의 올리고머 화합물을 포함하는 약제학적 조성물이 기재된다. 특정 실시형태에서, 1종 이상의 올리고머 화합물은 각각 변형된 올리고뉴클레오타이드로 이루어진다. 특정 실시형태에서, 약제학적 조성물은 약제학적으로 허용 가능한 희석제 또는 담체를 포함한다. 특정 실시형태에서, 약제학적 조성물은 무균 식염수 용액 및 1종의 올리고머 화합물을 포함하거나 이것으로 이루어진다. 특정 실시형태에서, 무균 식염수는 약제학적 등급 식염수이다. 특정 실시형태에서, 약제학적 조성물은 1종 이상의 올리고머 화합물 및 무균수를 포함하거나 이것으로 이루어진다 특정 실시형태에서, 무균수는 약제학적 등급 물이다. 특정 실시형태에서, 약제학적 조성물은 1종 이상의 올리고머 화합물 및 인산염 완충 식염수(PBS)를 포함하거나 이것으로 이루어진다 특정 실시형태에서, 무균 PBS는 약제학적 등급 PBS이다. 특정 실시형태에서, 약제학적 조성물은 1종 이상의 올리고머 화합물 및 인공 뇌척수액을 포함하거나 이것으로 이루어진다 특정 실시형태에서, 인공 뇌척수액은 약제학적 등급이다.
특정 실시형태에서, 약제학적 조성물은 변형된 올리고뉴클레오타이드 및 인공 뇌척수액을 포함한다. 특정 실시형태에서, 약제학적 조성물은 변형된 올리고뉴클레오타이드 및 인공 뇌척수액으로 이루어진다. 특정 실시형태에서, 약제학적 조성물은 변형된 올리고뉴클레오타이드 및 인공 뇌척수액으로 본질적으로 이루어진다. 특정 실시형태에서, 인공 뇌척수액은 약제학적 등급이다.
특정 실시형태에서, 약제학적 조성물은 하나 이상의 올리고머 화합물 및 하나 이상의 부형제를 포함한다. 특정 실시형태에서, 부형제는 물, 염 용액, 알코올, 폴리에틸렌 글리콜, 젤라틴, 락토스, 아밀라제, 스테아르산마그네슘, 탤크, 규산, 점성 파라핀, 하이드록시메틸셀룰로스 및 폴리바이닐피롤리돈으로부터 선택된다.
특정 실시형태에서, 올리고머 화합물은 약제학적 조성물 또는 제제의 제조를 위해 약제학적으로 허용 가능한 활성 및/또는 불활성 물질과 혼합될 수 있다. 약제학적 조성물의 제제에 대한 조성물 및 방법은 투여 경로, 질환의 정도 또는 투여되는 용량(이들로 제한되지 않음)을 포함하는 다수의 기준에 따라 달라진다.
특정 실시형태에서, 올리고머 화합물을 포함하는 약제학적 조성물은 올리고머 화합물의 임의의 약제학적으로 허용 가능한 염, 올리고머 화합물의 에스터 또는 이러한 에스터의 염을 포함한다. 특정 실시형태에서, 하나 이상의 올리고뉴클레오타이드를 포함하는 올리고머 화합물을 포함하는 약제학적 조성물은, 인간을 포함하는 대상체에 대한 투여 시, 생물학적으로 활성인 대사물질 또는 이의 잔류물을 (직접적으로 또는 간접적으로) 제공할 수 있다. 따라서, 예를 들어 본 개시내용은 또한 올리고머 화합물의 약제학적으로 허용 가능한 염, 전구약물, 이러한 전구약물의 약제학적으로 허용 가능한 염 및 다른 생물등가물에 관한 것이다. 적합한 약제학적으로 허용 가능한 염은 나트륨염 및 칼륨염을 포함하지만, 이들로 제한되지 않는다. 특정 실시형태에서, 전구약물은 올리고뉴클레오타이드에 부착된 하나 이상의 접합체 기를 포함하고, 접합체 기는 신체 내의 내인성 뉴클레아제에 의해 절단된다.
지질 모이어티는 다양한 방법에서 핵산 치료에서 사용된다. 이러한 특정 방법에서, 핵산, 예컨대, 올리고머 화합물은 양이온성 지질 및 중성 지질의 혼합물로 이루어진 미리 형성된 리포솜 또는 리포플렉스에 도입된다. 특정 방법에서, 모노- 또는 폴리-양이온성 지질과의 DNA 복합체는 중성 지질의 존재 없이 형성된다. 특정 실시형태에서, 지질 모이어티는 특정 세포 또는 조직에 대한 약제학적 작용제의 분포를 증가시키도록 선택된다. 특정 실시형태에서, 지질 모이어티는 지방 조직에 대한 약제학적 작용제의 분포를 증가시키도록 선택된다. 특정 실시형태에서, 지질 모이어티는 근육 조직에 대한 약제학적 작용제의 분포를 증가시키도록 선택된다.
특정 실시형태에서, 약제학적 조성물은 전달 시스템을 포함한다. 전달 시스템의 예는 리포솜 및 에멀션을 포함하지만, 이들로 제한되지 않는다. 특정 전달 시스템은 특정 약제학적 조성물, 예를 들어 소수성 화합물을 포함하는 것을 제조하는 데 유용하다. 특정 실시형태에서, 특정 유기 용매, 예컨대, 다이메틸설폭사이드를 사용한다.
특정 실시형태에서, 약제학적 조성물은 특이적 조직 또는 세포 유형에 본 발명의 하나 이상의 약제학적 작용제를 전달하도록 설계된 하나 이상의 조직 특이적 전달 분자를 포함한다. 예를 들어, 특정 실시형태에서, 약제학적 조성물은 조직 특이적 항체로 코팅된 리포솜을 포함한다.
특정 실시형태에서, 약제학적 조성물은 공용매 시스템을 포함한다. 이러한 특정 공용매 시스템은 예를 들어 벤질 알코올, 비극성 계면활성제, 수혼화성 유기 중합체 및 수성 상을 포함한다. 특정 실시형태에서, 이러한 공용매 시스템은 소수성 화합물에 사용된다. 이러한 공용매 시스템의 비제한적인 예는 3% w/v의 벤질 알코올, 8% w/v의 비극성 계면활성제 폴리솔베이트 80™ 및 65% w/v의 폴리에틸렌 글리콜 300을 포함하는 절대 에탄올의 용액인 VPD 공용매 시스템이다. 이러한 공용매 시스템의 비율은 이의 용해도 및 독성 특징을 변경시키지 유의하게 않으면서 상당히 달라질 수 있다. 더욱이, 공용매 성분의 정체는 변할 수 있고, 예를 들어, 폴리솔베이트 80™ 대신에 다른 계면활성제를 사용할 수 있고, 폴리에틸렌 글리콜의 분율 크기는 변할 수 있고, 다른 생체적합성 중합체는 폴리에틸렌 글리콜, 예를 들어, 폴리바이닐 피롤리돈을 대체할 수 있고, 다른 당 또는 다당류는 덱스트로스를 대체할 수 있다.
특정 실시형태에서, 약제학적 조성물은 경구 투여를 위해 제조된다. 특정 실시형태에서, 약제학적 조성물은 협측 투여를 위해 제조된다. 특정 실시형태에서, 약제학적 조성물은 주사(예를 들어, 정맥내, 피하, 근육내, 척추강내(IT), 뇌실내(ICV) 등)에 의한 투여를 위해 제조된다. 이러한 특정 실시형태에서, 약제학적 조성물은 담체를 포함하고, 수성 용액, 예컨대, 물 또는 생리학적으로 상용성인 완충액, 예컨대, 행크 용액, 링거액 또는 생리학적 식염수 완충액 중에 제형화된다. 특정 실시형태에서, 다른 성분(예를 들어, 용해성을 돕거나 보존제로서 작용하는 성분)이 포함된다. 특정 실시형태에서, 주사용 현탁액은 적절한 액체 담체, 현탁화제 등을 사용하여 제조된다. 특정 주사용 약제학적 조성물은 단위 투여 형태, 예를 들어, 앰플 또는 다회-용량 용기에 존재한다. 특정 주사용 약제학적 조성물은 유성 또는 수성 비히클 중의 현탁액, 용액 또는 에멀션이고, 제형화제, 예컨대, 현탁화제, 안정화제 및/또는 분산제를 함유할 수 있다. 주사용 약제학적 조성물에서 사용하기에 적합한 특정 용매는 친유성 용매 및 지방 오일, 예컨대, 참깨유, 합성 지방산 에스터, 예컨대, 에틸 올레에이트 또는 트라이글리세리드 및 리포솜을 포함하지만, 이들로 제한되지 않는다.
특정 조건 하에서, 본 명세서에 개시된 특정 화합물은 산으로서 작용한다. 이러한 화합물은 양성자화된(유리산) 형태 또는 이온화된 형태로 또는 양이온(염) 형태로 회합되어 도시되거나 기재되지만, 이러한 화합물의 수성 용액은 이러한 형태 사이에서 평형으로 존재한다. 예를 들어, 수성 용액 중의 올리고뉴클레오타이드의 포스페이트 링키지는 유리산, 음이온 및 염 형태 사이에서 평형으로 존재한다. 달리 제시되지 않는 한, 본 명세서에 기재된 화합물은 이러한 모든 형태를 포함하도록 의도된다. 더욱이, 특정 올리고뉴클레오타이드는 수 개의 이러한 링키지를 갖고, 이들 각각은 평형으로 존재한다. 따라서, 용액 중의 올리고뉴클레오타이드는 모두 평형 상태의 다수의 위치에서의 형태의 앙상블로 존재한다. 용어 "올리고뉴클레오타이드"는 이러한 모든 형태를 포함하도록 의도된다. 도시된 구조는 본질적으로 단일 형태를 도시한다. 그럼에도 불구하고, 달리 제시되지 않는 한, 이러한 도시는 마찬가지로 상응하는 형태를 포함하도록 의도된다. 본 명세서에서, 용어 "또는 이의 염" 앞의 화합물의 유리산을 도시한 구조는 완전히 또는 부분적으로 양성자화/탈양성자화/양이온과 회합될 수 있는 이러한 모든 형태를 명확하게 포함한다. 특정 예에서, 하나 이상의 특정 양이온이 식별된다.
특정 실시형태에서, 변형된 올리고뉴클레오타이드 또는 올리고머 화합물은 나트륨을 함유하는 수용액 중에 존재한다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드 또는 올리고머 화합물은 칼륨을 함유하는 수용액 중에 존재한다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드 또는 올리고머 화합물은 PBS 중에 존재한다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드 또는 올리고머 화합물은 물 중에 존재한다. 이러한 특정 실시형태에서, 용액의 pH는 NaOH 및/또는 HCl을 사용하여 조정되어 목적하는 pH를 달성한다.
본 명세서에서, 특정 특이적 용량이 기재된다. 용량은 투여량 단위의 형태로 존재할 수 있다. 명확성을 위해서, 밀리그램 단위의 변형된 올리고뉴클레오타이드 또는 올리고머 화합물의 용량(또는 투여량 단위)은 변형된 올리고뉴클레오타이드 또는 올리고머 화합물의 유리산 형태의 질량을 나타낸다. 상기에 기재된 바와 같이, 수성 용액에서, 유리산은 음이온 형태 및 염 형태와 평형으로 존재한다. 그러나, 용량 계산의 목적으로, 변형된 올리고뉴클레오타이드 또는 올리고머 화합물은 용매-무함유, 아세트산나트륨 무함유, 무수, 유리산으로 존재한다고 가정한다. 예를 들어, 변형된 올리고뉴클레오타이드 또는 올리고머 화합물이 나트륨을 포함하는 용액(예를 들어, 식염수)에 존재하는 경우, 변형된 올리고뉴클레오타이드 또는 올리고머 화합물은 부분적으로 또는 완전히 탈양성자화되고, Na+ 이온과 회합하여 존재할 수 있다. 그러나, 그럼에도 불구하고 양성자의 질량은 용량의 중량에 대해서 계산되고, Na+ 이온의 질량은 용량의 중량에 대해서 계산되지 않는다. 따라서, 예를 들어, 100㎎의 용량 또는 투여량 단위의 화합물 번호 1263518은 100㎎ 중량의 완전히 양성자화된 분자의 수와 동일하다. 이것은 용매-무함유, 아세트산나트륨-무함유, 무수 나트륨화(sodiated) 화합물 번호 1263518의 106㎎과 동일할 것이다. 올리고머 화합물이 접합체 기를 포함하는 경우, 접합체 기의 질량은 이러한 올리고머 화합물의 용량을 계산하는데 포함된다. 접합체 기가 산을 갖는 경우, 접합체 기는 마찬가지로 용량 계산의 목적을 위해서 완전히 양성자화된다고 가정된다.
VII. 특정 조성물
1. 화합물 번호 1065645
특정 실시형태에서, 화합물 번호 1065645는 (5'에서 3'로) CATCATGATCTTGGTAAGGC(서열번호 1949)의 서열을 갖는 5-10-5 MOE 갭머인 것을 특징으로 하며, 여기서 뉴클레오사이드 1 내지 5 및 16 내지 20(5'에서 3'로) 각각은 2'-MOE 뉴클레오사이드이고, 뉴클레오사이드 6 내지 15 각각은 2'-β-D-데옥시뉴클레오사이드이며, 뉴클레오사이드 2에서 3, 3에서 4, 4에서 5, 5에서 6, 16에서 17 및 17에서 18 사이의 뉴클레오사이드간 링키지는 포스포다이에스터 뉴클레오사이드간 링키지이고, 뉴클레오사이드 1에서 2, 6에서 7, 7에서 8, 8에서 9, 9에서 10, 10에서 11, 11에서 12, 12에서 13, 13에서 14, 14에서 15, 15에서 16, 18에서 19, 및 19에서 20 사이의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이며, 각각의 사이토신은 5-메틸 사이토신이다.
특정 실시형태에서, 화합물 번호 1065645는 하기 화학적 표기로 표현된다: mCesAeoTeo mCeoAeoTdsGdsAdsTds mCdsTdsTdsGdsGdsTdsAeoAeoGesGes mCe(서열번호 1949),
식 중,
A = 아데닌 핵염기이고,
mC = 5-메틸 사이토신 핵염기이며,
G = 구아닌 핵염기이고,
T = 티민 핵염기이며,
e = 2'-MOE 당 모이어티이고,
d = 2'-β-D-데옥시리보실 당 모이어티이고,
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고,
o = 포스포다이에스터 뉴클레오사이드간 링키지이다.
특정 실시형태에서, 화합물 번호 1065645는 하기 화학 구조로 표현된다:
Figure pct00019
구조 1. 화합물 번호 1065645
특정 실시형태에서, 화합물 번호 1065645의 나트륨염은 하기 화학 구조로 표현된다:
Figure pct00020
구조 2. 화합물 번호 1065645의 나트륨염
2. 화합물 번호 1263517
특정 실시형태에서, 화합물 번호 1263517은 (5'에서 3'로) TCACCATTTTGACCTTCTTA(서열번호 2751)의 서열을 갖는 6-10-4 MOE 갭머인 것을 특징으로 하며, 여기서 뉴클레오사이드 1 내지 6 및 17 내지 20(5'에서 3'로) 각각은 2'-MOE 뉴클레오사이드이고, 뉴클레오사이드 7 내지 16은 각각 2'-β-D-데옥시뉴클레오사이드이며, 뉴클레오사이드 2 에서 3, 3 에서 4, 4 에서 5, 5 에서 6, 6 에서 7 및 17 에서 18 사이의 뉴클레오사이드간 링키지는 포스포다이에스터 뉴클레오사이드간 링키지이고, 뉴클레오사이드 1에서 2, 7에서 8, 8에서 9, 9에서 10, 10에서 11, 11에서 12, 12에서 13, 13에서 14, 14에서 15, 15에서 16, 16에서 17, 18에서 19, 및 19에서 20 사이의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이며, 각각의 사이토신은 5-메틸 사이토신이다.
특정 실시형태에서, 화합물 번호 1263517은 하기 화학적 표기로 표현된다: Tes mCeoAeo mCeo mCeoAeoTdsTdsTdsTdsGdsAds mCds mCdsTdsTds mCeoTesTesAe(서열번호 2751),
식 중,
A = 아데닌 핵염기이고,
mC = 5-메틸 사이토신 핵염기이며,
G = 구아닌 핵염기이고,
T = 티민 핵염기이며,
e = 2'-MOE 당 모이어티이고,
d = 2'-β-D-데옥시리보실 당 모이어티이고,
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고,
o = 포스포다이에스터 뉴클레오사이드간 링키지이다.
특정 실시형태에서, 화합물 번호 1263517은 하기 화학 구조로 표현된다:
Figure pct00021
구조 3. 화합물 번호 1263517
특정 실시형태에서, 화합물 번호 1263517의 나트륨염은 하기 화학 구조로 표현된다:
Figure pct00022
구조 4. 화합물 번호 1263517의 나트륨염
3. 화합물 번호 1263518
특정 실시형태에서, 화합물 번호 1263518은 (5'에서 3'로) TTCACCATTTTGACCTTCTT(서열번호 2752)의 서열을 갖는 6-10-4 MOE 갭머인 것을 특징으로 하며, 여기서 뉴클레오사이드 1 내지 6 및 17 내지 20(5'에서 3'로) 각각은 2'-MOE 뉴클레오사이드이고, 뉴클레오사이드 7 내지 16 각각은 2'-β-D-데옥시뉴클레오사이드이며, 뉴클레오사이드 2에서 3, 3에서 4, 4에서 5, 5에서 6, 6에서 7 및 17에서 18 사이의 뉴클레오사이드간 링키지는 포스포다이에스터 뉴클레오사이드간 링키지이고, 뉴클레오사이드 1에서 2, 7에서 8, 8에서 9, 9에서 10, 10에서 11, 11에서 12, 12에서 13, 13에서 14, 14에서 15, 15에서 16, 16에서 17, 18에서 19, 및 19에서 20 사이의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이며, 각각의 사이토신은 5-메틸 사이토신이다.
특정 실시형태에서, 화합물 번호 1263518은 하기 화학적 표기로 표현된다: TesTeo mCeoAeo mCeo mCeoAdsTdsTdsTdsTdsGdsAds mCds mCdsTdsTeo mCesTesTe(서열번호 2752),
식 중,
A = 아데닌 핵염기이고,
mC = 5-메틸 사이토신 핵염기이며,
G = 구아닌 핵염기이고,
T = 티민 핵염기이며,
e = 2'-MOE 당 모이어티이고,
d = 2'-β-D-데옥시리보실 당 모이어티이고,
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고,
o = 포스포다이에스터 뉴클레오사이드간 링키지이다.
특정 실시형태에서, 화합물 번호 1263518은 하기 화학 구조로 표현된다:
Figure pct00023
구조 5. 화합물 번호 1263518
특정 실시형태에서, 화합물 번호 1263518의 나트륨염은 하기 화학 구조로 표현된다:
Figure pct00024
구조 6. 화합물 번호 1263518의 나트륨염
4. 화합물 번호 1263533
특정 실시형태에서, 화합물 번호 1263533은 (5'에서 3'로) GCATACCCAGGGTAGGATTC(서열번호 765)의 서열을 갖는 6-10-4 MOE 갭머인 것을 특징으로 하며, 여기서 뉴클레오사이드 1 내지 6 및 17 내지 20(5'에서 3'로) 각각은 2'-MOE 뉴클레오사이드이고, 뉴클레오사이드 7 내지 16은 각각 2'-β-D-데옥시뉴클레오사이드이며, 뉴클레오사이드 2 에서 3, 3에서 4, 4 에서 5, 5 에서 6, 6 에서 7 및 17 에서 18 사이의 뉴클레오사이드간 링키지는 포스포다이에스터 뉴클레오사이드간 링키지이고, 뉴클레오사이드 1에서 2, 7에서 8, 8에서 9, 9에서 10, 10에서 11, 11에서 12, 12에서 13, 13에서 14, 14에서 15, 15에서 16, 16에서 17, 18에서 19, 및 19에서 20 사이의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이며, 각각의 사이토신은 5-메틸 사이토신이다.
특정 실시형태에서, 화합물 번호 1263533은 하기 화학적 표기로 표현된다: Ges mCeoAeoTeoAeo mCeo mCds mCdsAdsGdsGdsGdsTdsAdsGdsGdsAeoTesTes mCe(서열번호 765),
식 중,
A = 아데닌 핵염기이고,
mC = 5-메틸 사이토신 핵염기이며,
G = 구아닌 핵염기이고,
T = 티민 핵염기이며,
e = 2'-MOE 당 모이어티이고,
d = 2'-β-D-데옥시리보실 당 모이어티이고,
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고,
o = 포스포다이에스터 뉴클레오사이드간 링키지이다.
특정 실시형태에서, 화합물 번호 1263533은 하기 화학 구조로 표현된다:
Figure pct00025
구조 7. 화합물 번호 1263533
특정 실시형태에서, 화합물 번호 1263533의 나트륨염은 하기 화학 구조로 표현된다:
Figure pct00026
구조 8. 화합물 번호 1263533의 나트륨염
5. 화합물 번호 1273039
특정 실시형태에서, 화합물 번호 1273039는 (5'에서 3'로) ACGCAATGTATCAGGCAA(서열번호 2866)의 서열을 갖는 4-8-6 MOE 갭머인 것을 특징으로 하며, 뉴클레오사이드 1 내지 4 및 13 내지 18(5'에서 3'로) 각각은 2'-MOE 뉴클레오사이드이고, 뉴클레오사이드 5 내지 12 각각은 2'-β-D-데오시뉴클레오사이드이고, 여기서 뉴클레오사이드 2에서 3, 3에서 4, 13에서 14, 14에서 15 및 15에서 16 사이의 뉴클레오사이드간 링키지는 포스포다이에스터 뉴클레오사이드간 링키지이고, 뉴클레오사이드 1에서 2, 4에서 5, 5에서 6, 6에서 7, 7에서 8, 8에서 9, 9에서 10, 10에서 11, 11에서 12, 12에서 13, 16에서 17 및 17에서 18 사이의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이고, 각각의 사이토신은 5-메틸 사이토신이다.
특정 실시형태에서, 화합물 번호 1273039는 하기 화학적 표기로 표현된다: Aes mCeoGeo mCesAdsAdsTdsGdsTdsAdsTds mCdsAeoGeoGeo mCesAesAe(서열번호 2866),
식 중,
A = 아데닌 핵염기이고,
mC = 5-메틸 사이토신 핵염기이며,
G = 구아닌 핵염기이고,
T = 티민 핵염기이며,
e = 2'-MOE 당 모이어티이고,
d = 2'-β-D-데옥시리보실 당 모이어티이고,
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고,
o = 포스포다이에스터 뉴클레오사이드간 링키지이다.
특정 실시형태에서, 화합물 번호 1273039는 하기 화학 구조로 표현된다:
Figure pct00027
구조 9. 화합물 번호 1273039
특정 실시형태에서, 화합물 번호 1273039의 나트륨염은 하기 화학 구조로 표현된다:
Figure pct00028
구조 10. 화합물 번호 1273039의 나트륨염
6. 화합물 번호 1273062
특정 실시형태에서, 화합물 번호 1273062은 (5'에서 3'로) ACCATTTTGACCTTCTTAGC(서열번호 2873)의 서열을 갖는 5-10-5 MOE 갭머인 것을 특징으로 하며, 여기서 뉴클레오사이드 1 내지 5 및 16 내지 20(5'에서 3'로) 각각은 2'-MOE 뉴클레오사이드이고, 뉴클레오사이드 6 내지 15 각각은 2'-β-D-데옥시뉴클레오사이드이며, 뉴클레오사이드 2에서 3, 3에서 4, 4에서 5, 5에서 6, 16에서 17 및 17에서 18 사이의 뉴클레오사이드간 링키지는 포스포다이에스터 뉴클레오사이드간 링키지이고, 뉴클레오사이드 1에서 2, 6에서 7, 7에서 8, 8에서 9, 9에서 10, 10에서 11, 11에서 12, 12에서 13, 13에서 14, 14에서 15, 15에서 16, 18에서 19, 및 19에서 20 사이의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이며, 각각의 사이토신은 5-메틸 사이토신이다.
특정 실시형태에서, 화합물 번호 1273062는 하기 화학적 표기로 표현된다: Aes mCeo mCeoAeoTeoTdsTdsTdsGdsAds mCds mCdsTdsTds mCdsTeoTeoAesGes mCe(서열번호 2873),
식 중,
A = 아데닌 핵염기이고,
mC = 5-메틸 사이토신 핵염기이며,
G = 구아닌 핵염기이고,
T = 티민 핵염기이며,
e = 2'-MOE 당 모이어티이고,
d = 2'-β-D-데옥시리보실 당 모이어티이고,
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고,
o = 포스포다이에스터 뉴클레오사이드간 링키지이다.
특정 실시형태에서, 화합물 번호 1273062는 하기 화학 구조로 표현된다:
Figure pct00029
구조 11. 화합물 번호 1273062
특정 실시형태에서, 화합물 번호 1273062의 나트륨염은 하기 화학 구조로 표현된다:
Figure pct00030
구조 12. 화합물 번호 1273062의 나트륨염
VIII. 특정 비교 화합물
특정 실시형태에서, WO2017/081223(본 명세서에 참조에 의해 포함됨)에 제공된 (화합물 #586_9)의 대용체인 화합물 번호 1219022를 비교 화합물로서 사용하였다. 화합물 번호 1219022를 (5'에서 3'로) llddldldddddddddllll(식 중, 각각의 "l"은 LNA 당 모이어티를 나타내고, 각각의 "d"는 2'-β-D-데옥시리보실 당 모이어티를 나타냄)의 당 모티프를 갖고, (5'에서 3'로) AAATTATTTATACACCATCA(서열번호 2905)(식 중, 각각의 "C"는 5-메틸 사이토신임)를 갖는 LNA/DNA 올리고뉴클레오타이드와 혼합하고; 여기서 각각의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이다. 화합물 #586_9는 13, 15, 및 16번 위치에 사이토신을 갖는 반면, 화합물 번호 1219022는 이들 위치에 5-메틸 사이토신을 갖는다. Wan 및 Seth에 따르면, "사이토신 상에 5-메틸기를 도입하는 것은 특정 DNA 올리고뉴클레오타이드의 면역자극 프로파일을 감소시키고, 또한 뉴클레아제 안정성을 향상시킨다"(J. Med. Chem. 2016, 59, 9645-9667).
특정 실시형태에서, WO2017/081223(본 명세서에 참조에 의해 포함됨)에 제공된 (화합물 #572_7)의 대용체인 화합물 번호 1219023을 비교 화합물로서 사용하였다. 화합물 번호 1219023을 (5'에서 3'로) lllddldddddddddlll(식 중, 각각의 "l"은 LNA 당 모이어티를 나타내고, 각각의 "d"는 2'-β-D-데옥시리보실 당 모이어티를 나타냄)의 당 모티프를 갖고, (5'에서 3'로) TTTATCAATATCTTCTCA(서열번호 2906)(식 중, 각각의 "C"는 5-메틸 사이토신임)를 갖는 LNA/DNA 올리고뉴클레오타이드와 혼합하고; 여기서 각각의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이다. 화합물 #572_7는 12 및 15번 위치에 사이토신을 갖는 반면, 화합물 번호 1219023은 이들 위치에 5-메틸 사이토신을 갖는다.
특정 실시형태에서, WO2017/081223(본 명세서에 참조에 의해 포함됨)에 제공된 (화합물 #591_1)의 대용체인 화합물 번호 1219024를 비교 화합물로서 사용하였다. 화합물 번호 1219024를 (5'에서 3'로) ldldlddddddddddddll(식 중, 각각의 "l"은 LNA 당 모이어티를 나타내고, 각각의 "d"는 2'-β-D-데옥시리보실 당 모이어티를 나타냄)의 당 모티프를 갖고, (5'에서 3'로) GCACATTCTTTCTATACCT(서열번호 2907)(식 중, 각각의 "C"는 5-메틸 사이토신임)를 갖는 LNA/DNA 올리고뉴클레오타이드와 혼합하고; 여기서 각각의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이다. 화합물 #591_1은 2, 4, 8, 12 및 17번 위치에 사이토신을 갖는 반면, 화합물 번호 1219024는 이들 위치에 5-메틸 사이토신을 갖는다.
특정 실시형태에서, WO2017/081223(본 명세서에 참조에 의해 포함됨)에 제공된 (화합물 #169_52)의 대용체인 화합물 번호 1219025를 비교 화합물로서 사용하였다. 화합물 번호 1219025를 (5'에서 3'로) lldllddddddddddll(식 중, 각각의 "l"은 LNA 당 모이어티를 나타내고, 각각의 "d"는 2'-β-D-데옥시리보실 당 모이어티를 나타냄)의 당 모티프를 갖고, (5'에서 3'로) TTATAGCCATTCTATCT(서열번호 2908)(식 중, 각각의 "C"는 5-메틸 사이토신임)를 갖는 LNA/DNA 올리고뉴클레오타이드와 혼합하고; 여기서 각각의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이다. 화합물 #169_52는 7, 8 및 12번 위치에 사이토신을 갖는 반면, 화합물 번호 1219025는 이들 위치에 5-메틸 사이토신을 갖는다.
특정 실시형태에서, WO2017/081223(본 명세서에 참조에 의해 포함됨)에 제공된 (화합물 #624_5)의 대용체인 화합물 번호 1219026을 비교 화합물로서 사용하였다. 화합물 번호 1219026을 (5'에서 3'로) ldlllddddddddllll(식 중, 각각의 "l"은 LNA 당 모이어티를 나타내고, 각각의 "d"는 2'-β-D-데옥시리보실 당 모이어티를 나타냄)의 당 모티프를 갖고, (5'에서 3'로) CTCAAAGATCATTCTCA(서열번호 2909)(식 중, 각각의 "C"는 5-메틸 사이토신임)를 갖는 LNA/DNA 올리고뉴클레오타이드와 혼합하고; 여기서 각각의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이다. 화합물 # 624_5는 10번 위치에 사이토신을 갖는 반면, 화합물 번호 1219026은 그 위치에 5-메틸 사이토신을 갖는다.
특정 실시형태에서, WO2017/081223(본 명세서에 참조에 의해 포함됨)에 제공된 (화합물 #626_8)의 대용체인 화합물 번호 1219027을 비교 화합물로서 사용하였다. 화합물 번호 1219027을 (5'에서 3'로) ldldldldddddddddldll(식 중, 각각의 "l"은 LNA 당 모이어티를 나타내고, 각각의 "d"는 2'-β-D-데옥시리보실 당 모이어티를 나타냄)의 당 모티프를 갖고, (5'에서 3'로) TTACACTTAATTATACTTCC(서열번호 2910)(식 중, 각각의 "C"는 5-메틸 사이토신임)를 갖는 LNA/DNA 올리고뉴클레오타이드와 혼합하고; 여기서 각각의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이다. 화합물 #626_8은 4, 6 및 16번 위치에 사이토신을 갖는 반면, 화합물 번호 1219027은 이들 위치에 5-메틸 사이토신을 갖는다.
특정 실시형태에서, WO2017/081223(본 명세서에 참조에 의해 포함됨)에 제공된 (화합물 #639_5)의 대용체인 화합물 번호 1219028을 비교 화합물로서 사용하였다. 화합물 번호 1219028을 (5'에서 3'로) ldddddddddddlldlll(식 중, 각각의 "l"은 LNA 당 모이어티를 나타내고, 각각의 "d"는 2'-β-D-데옥시리보실 당 모이어티를 나타냄)의 당 모티프를 갖고, (5'에서 3'로) GTTTCCATCTACTATTAA(서열번호 2911)(식 중, 각각의 "C"는 5-메틸 사이토신임)를 갖는 LNA/DNA 올리고뉴클레오타이드와 혼합하고; 여기서 각각의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이다. 화합물 #639_5는 5, 6, 9 및 12번 위치에 사이토신을 갖는 반면, 화합물 번호 1219028은 이들 위치에 5-메틸 사이토신을 갖는다.
특정 실시형태에서, WO2017/081223(본 명세서에 참조에 의해 포함됨)에 제공된 (화합물 #642_12)의 대용체인 화합물 번호 1219029를 비교 화합물로서 사용하였다. 화합물 번호 1219029를 (5'에서 3'로) llddlddddddddddll(식 중, 각각의 "l"은 LNA 당 모이어티를 나타내고, 각각의 "d"는 2'-β-D-데옥시리보실 당 모이어티를 나타냄)의 당 모티프를 갖고, (5'에서 3'로) CTGTATACACCATCCCA(서열번호 2912)(식 중, 각각의 "C"는 5-메틸 사이토신임)를 갖는 LNA/DNA 올리고뉴클레오타이드와 혼합하고; 여기서 각각의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이다. 화합물 #642_12는 8, 10, 11, 14 및 15번 위치에 사이토신을 갖는 반면, 화합물 번호 1219029는 이들 위치에 5-메틸 사이토신을 갖는다.
특정 실시형태에서, WO2017/081223(본 명세서에 참조에 의해 포함됨)에 제공된 (화합물 #304_6)의 대용체인 화합물 번호 1219030을 비교 화합물로서 사용하였다. 화합물 번호 1219030을 (5'에서 3'로) lddllddddddddllll(식 중, 각각의 "l"은 LNA 당 모이어티를 나타내고, 각각의 "d"는 2'-β-D-데옥시리보실 당 모이어티를 나타냄)의 당 모티프를 갖고, (5'에서 3'로) AGTTCTACTATACTTTC(서열번호 2913)(식 중, 각각의 "C"는 5-메틸 사이토신임)를 갖는 LNA/DNA 올리고뉴클레오타이드와 혼합하고; 여기서 각각의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이다. 화합물 #304_6은 8 및 13번 위치에 사이토신을 갖는 반면, 화합물 번호 1219030은 이들 위치에 5-메틸 사이토신을 갖는다.
특정 실시형태에서, WO2017/081223(본 명세서에 참조에 의해 포함됨)에 제공된 (화합물 #573_8)의 대용체인 화합물 번호 1219031을 비교 화합물로서 사용하였다. 화합물 번호 1219031을 (5'에서 3'로) llddldldddddddddddll(식 중, 각각의 "l"은 LNA 당 모이어티를 나타내고, 각각의 "d"는 2'-β-D-데옥시리보실 당 모이어티를 나타냄)의 당 모티프를 갖고, (5'에서 3'로) TATACCTTTCTTTAACCCTT(서열번호 2914)(식 중, 각각의 "C"는 5-메틸 사이토신임)를 갖는 LNA/DNA 올리고뉴클레오타이드와 혼합하고; 여기서 각각의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이다. 화합물 #573_8은 6, 10, 16, 17 및 18번 위치에 사이토신을 갖는 반면, 화합물 번호 1219031은 이들 위치에 사이토신을 갖는다.
화합물 번호 1219022 내지 1219031(각각 화합물 번호 #586_9, #572_7, #591_1, #169_52, #624_5, #626_8, #639_5 #642_12, #304_6, #573_8)을 WO2017/081223의 실시예 7로부터의 비교 화합물로서 선택하였는데, 이것은 "효력 및 효능 시험을 위해서 선택된" 활성 화합물의 하위세트를 제공한다.
특정 실시형태에서, 본 명세서에 기재된 화합물은 WO2017/081223에 기재된 화합물에 비해서 우수한데, 그 이유는 이들이 하나 이상의 개선된 특성, 예컨대, 생체내 내약성을 나타내기 때문이다.
예를 들어, 본 명세서에 기재된 바와 같이, 특정 화합물인 화합물 번호 1263517, 화합물 번호 1263518, 화합물 번호 1263533, 화합물 번호 1273039 및 화합물 번호 1273062는 각각 1.0(표 88), 0.0(표 88), 1.0(표 88), 1.0(표 96) 및 0.0(표 96)의 마우스에서의 3시간 FOB 점수를 달성한 반면, 비교 화합물인 화합물 번호 1219022, 화합물 번호 1219024, 화합물 번호 1219025, 화합물 번호 1219028, 화합물 번호 1219029, 화합물 번호 1219030 및 화합물 번호 1219031 각각은 각각 7.0, 5.3, 4.0, 6.0, 6.3, 5.0 및 5.3(표 119)의 3시간 FOB 점수를 달성하였다. 따라서, 본 명세서에 기재된 특정 화합물은 이러한 검정에서 비교 화합물인 화합물 번호 1219022, 화합물 번호 1219024, 화합물 번호 1219025, 화합물 번호 1219028, 화합물 번호 1219029, 화합물 번호 1219030 및 화합물 번호 1219031보다 더 내약성이다.
예를 들어, 본 명세서에 기재된 바와 같이, 특정 화합물인 화합물 번호 1065645, 화합물 번호 1263517, 화합물 번호 1263518, 화합물 번호 1263533, 화합물 번호 1273039 및 화합물 번호 1273062 각각은 0.0(실시예 12, 표 112)의 마우스에서의 2주 FOB 점수를 달성한 반면, 화합물 번호 1219023, 화합물 번호 1219024, 화합물 번호 1219025, 화합물 번호 1219026, 화합물 번호 1219028, 화합물 번호 1219029, 화합물 번호 1219030 및 화합물 번호 1219031은 각각 3.5, 6.5, 6.0, 6.0, 6.0, 6.0, 6.0, 5.0 및 6.0의 마우스에서의 2주 지연된 FOB 점수를 달성하였다(표 119). 따라서, 본 명세서에 기재된 특정 화합물은 이러한 검정에서 비교 화합물인 화합물 번호 1219023 및 화합물 번호 1219026보다 더 내약성이다.
예를 들어, 본 명세서에 기재된 바와 같이, 특정 화합물인 화합물 번호 1065645, 화합물 번호 1263517, 화합물 번호 1263518, 화합물 번호 1263533, 화합물 번호 1273039 및 화합물 번호 1273062는 8주 연구에서 PBS-처리된 래트와 비교할 때 체중에서 상당한 변화를 유발하지 않은 반면, 화합물 번호 1219027로의 처리는 PBS-처리된 래트(p-값 <0.05, 표 120)에 비해서 10%를 초과하는 체중 감소를 유발한다. 따라서, 본 명세서에 기재된 특정 화합물은 이러한 검정에서 비교 화합물 번호 1219027보다 더 양호하게 내약성이다.
IX. 특정 핫스팟 영역
특정 실시형태에서, 하기에 명시된 범위의 핵염기는 UBE3A-ATS의 핫스팟 영역을 포함한다. 특정 실시형태에서, UBE3A-ATS의 핫스팟 영역과 상보성인 변형된 올리고뉴클레오타이드는 시험관내 표준 세포 검정에서 UBE3A-ATS RNA의 평균 50% 초과의 감소를 달성한다.
1. 서열번호 1의 핵염기 461,413 내지 461,487
특정 실시형태에서, 서열번호 1의 핵염기 461,413 내지 461,487은 핫스팟 영역을 포함한다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 서열번호 1의 핵염기 461,413 내지 461,487의 부분과 상보성이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 20개 핵염기 길이이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 18개 핵염기 길이이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 갭머이다. 특정 실시형태에서, 갭머는 MOE 갭머이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지 및 포스포다이에스터 뉴클레오사이드간 링키지이다. 특정 실시형태에서, 포스포다이에스터("o") 및 포스포로티오에이트("s") 뉴클레오사이드간 링키지는 5'에서 3'의 순서로 soooossssssssssooss, sooooossssssssssoss, soooosssssssssoss, sooosssssssssooss, sooossssssssssoooss 또는 soosssssssssoooss로 배열된다.
서열번호 1053, 1329, 1501, 1576, 1873, 1949, 2025, 2096, 2245, 2512, 2591, 2680 내지 2682 및 2844의 핵염기 서열은 서열번호 1의 핵염기 461,413 내지 461,487의 부분과 상보성이다.
화합물 번호 749901 내지 749904, 1065641 내지 1065646, 1165562 내지 1165563, 1165857 내지 1165858 및 1273001의 핵염기 서열은 서열번호 1의 핵염기 461,413 내지 461,487의 부분과 상보성이다.
특정 실시형태에서, 서열번호 1의 핵염기 461,413 내지 461,487의 부분과 상보성인 변형된 올리고뉴클레오타이드는 시험관내 표준 세포 검정에서 UBE3A-ATS RNA의 적어도 36% 감소를 달성한다. 특정 실시형태에서, 서열번호 1의 핵염기 461,413 내지 461,487의 부분과 상보성인 변형된 올리고뉴클레오타이드는 시험관내 표준 세포 검정에서 UBE3A-ATS RNA의 평균 60% 감소를 달성한다.
2. 서열번호 1의 핵염기 468,968 내지 469,013
특정 실시형태에서, 서열번호 1의 핵염기 468,968 내지 469,013은 핫스팟 영역을 포함한다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 서열번호 1의 핵염기 468,968 내지 469,013의 부분과 상보성이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 20개 핵염기 길이이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 18개 핵염기 길이이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 갭머이다. 특정 실시형태에서, 갭머는 MOE 갭머이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지 및 포스포다이에스터 뉴클레오사이드간 링키지이다. 특정 실시형태에서, 포스포다이에스터("o") 및 포스포로티오에이트("s") 뉴클레오사이드간 링키지는 5'에서 3'의 순서로 soooossssssssssooss, sooooossssssssssoss, soooosssssssssoss, sooosssssssssooss, sooossssssssssoooss 또는 soosssssssssoooss로 배열된다.
서열번호 376, 377, 2751 내지 2756, 2773 내지 2776, 2872, 2873, 2876 내지 2878의 핵염기 서열은 서열번호 1의 핵염기 468,968 내지 469,013의 부분과 상보성이다.
화합물 번호 750031 내지 750032, 1263408 내지 1263411, 1263426, 1263441, 1263460 내지 1263465, 1263486 내지 1263492, 1263517 내지 1263523, 1273061, 1273062 및 1273065 내지 1273067은 서열번호 1의 핵염기 468,968 내지 469,013의 부분과 상보성이다.
특정 실시형태에서, 서열번호 1의 핵염기 468,968 내지 469,013의 부분과 상보성인 변형된 올리고뉴클레오타이드는 시험관내 표준 세포 검정에서 UBE3A-ATS RNA의 적어도 75% 감소를 달성한다. 특정 실시형태에서, 서열번호 1의 핵염기 468,968 내지 469,013의 부분과 상보성인 변형된 올리고뉴클레오타이드는 시험관내 표준 세포 검정에서 UBE3A-ATS RNA의 평균 78% 감소를 달성한다. 특정 실시형태에서, 서열번호 1의 핵염기 468,968 내지 469,013의 부분과 상보성인 변형된 올리고뉴클레오타이드는 세포 배양물에서 시험관내에서 6.7μM에서 UBE3A-ATS RNA의 평균 410% 상향조절을 달성한다.
3. 서열번호 1의 핵염기 483,965 내지 484,003
특정 실시형태에서, 서열번호 1의 핵염기 483,965 내지 484,003은 핫스팟 영역을 포함한다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 서열번호 1의 핵염기 483,965 내지 484,003의 부분과 상보성이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 20개 핵염기 길이이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 18개 핵염기 길이이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 갭머이다. 특정 실시형태에서, 갭머는 MOE 갭머이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지 및 포스포다이에스터 뉴클레오사이드간 링키지이다. 특정 실시형태에서, 포스포다이에스터("o") 및 포스포로티오에이트("s") 뉴클레오사이드간 링키지는 5'에서 3'의 순서로 soooossssssssssooss, sooooossssssssssoss, soooosssssssssoss, sooosssssssssooss, sooossssssssssoooss 또는 soosssssssssoooss로 배열된다.
서열번호 172, 764 내지 770, 995, 1445, 1668, 1743, 2255, 2595, 2762 내지 2767의 핵염기 서열은 서열번호 1의 핵염기 483,965 내지 484,003의 부분과 상보성이다.
화합물 번호 617557, 699781, 750138 내지 750144, 1065918 내지 1065921, 1165621, 1165878 및 1263532 내지 1263557은 서열번호 1의 핵염기 483,965 내지 484,003의 부분과 상보성이다.
특정 실시형태에서, 서열번호 1의 핵염기 483,965 내지 484,003의 부분과 상보성인 변형된 올리고뉴클레오타이드는 시험관내 표준 세포 검정에서 UBE3A-ATS RNA의 적어도 24% 감소를 달성한다. 특정 실시형태에서, 서열번호 1의 핵염기 483,965 내지 484,003과 상보성인 변형된 올리고뉴클레오타이드는 시험관내 표준 세포 검정에서 UBE3A-ATS RNA의 평균 65% 감소를 달성한다. 특정 실시형태에서, 서열번호 1의 핵염기 468,968 내지 469,013의 부분과 상보성인 변형된 올리고뉴클레오타이드는 세포 배양물에서 시험관내에서 6.7μM에서 UBE3A-ATS RNA의 평균 330% 상향조절을 달성한다.
4. 추가 핫스팟 영역
특정 실시형태에서, 하기 표에 기재된 범위는 핫스팟 영역을 포함한다. 각각의 핫스팟 영역은 "시작 부위 서열번호 1" 칼럼에 식별된 서열번호 1의 핵염기에서 시작하고, "종결 부위 서열번호 1" 칼럼에 식별된 서열번호 1의 핵염기에서 끝난다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 하기 표에 정의된 바와 같이, 핫스팟 영역 1 내지 61 중 임의의 것에서 상보성이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 18개 핵염기 길이이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 20개 핵염기 길이이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 갭머이다. 특정 실시형태에서, 변형된 올리고뉴클레오타이드는 4-8-6, 6-8-4, 5-8-5, 4-10-6, 6-10-4 또는 5-10-5 MOE 갭머이다.
하기 표에서 "범위의 화합물 ID" 칼럼에 열거된 화합물의 핵염기 서열은 명시된 핫스팟 영역 내에서 서열번호 1과 상보성이다. 하기 표에서 "범위의 서열번호" 칼럼에 열거된 올리고뉴클레오타이드의 핵염기 서열은 명시된 핫스팟 영역 내에서 표적 서열, 서열번호 1과 상보성이다.
특정 실시형태에서, 핫스팟 영역 내의 핵염기와 상보성인 변형된 올리고뉴클레오타이드는 하기 표에 제시된 바와 같은, 표준 세포 검정에서 시험관내에서 UBE3A-ATS RNA의 최소 "최소 감소 %"(미처리 대조군 세포와 비교한, 최소 감소 %)를 달성한다. 특정 실시형태에서, 핫스팟 영역 내의 핵염기와 상보성인 변형된 올리고뉴클레오타이드는 하기 표에 제시된 바와 같은, 표준 세포 검정에서 시험관내에서 UBE3A-ATS RNA의 적어도 "평균 감소 %"(미처리 대조군 세포와 비교한, 평균 감소 %)를 달성한다. 특정 실시형태에서, 핫스팟 영역 내의 핵염기와 상보성인 변형된 올리고뉴클레오타이드는 하기 표에 제시된 바와 같은, 표준 세포 검정에서 시험관내에서 UBE3A-ATS RNA의 "최대 감소 %"의 최대치(미처리 대조군 세포와 비교한, 최대 감소 %)를 달성한다.
Figure pct00031
Figure pct00032
Figure pct00033
비제한적인 개시내용 및 참조에 의한 포함
본 명세서에 열거된 각각의 문헌 및 특허 공보는 그 전문이 참고에 의해 포함된다.
본 명세서에 기재된 특정 화합물, 조성물 및 방법이 특정 실시형태에 따라 구체적으로 기재되어 있지만, 하기 실시예는 단지 본 명세서에 기재된 화합물을 예시하기 위해서 제공되며, 이를 제한하는 것으로 의도되지 않는다. 본 출원에 기재된 각각의 참고문헌, 진뱅크 수탁 번호 등은 그 전문이 참조에 의해 본 명세서에 포함된다.
본 출원에 첨부된 서열 목록은 필요한 경우 "RNA" 또는 "DNA"로서 각각의 서열을 식별하지만, 실제로, 이 서열은 화학 변형의 임의의 조합에 의해 변형될 수 있다. 당업자는 변형된 올리고뉴클레오타이드를 기재하기 위한 "RNA" 또는 "DNA"로서의 이의 지칭이 특정 경우에 임의적이라는 것을 용이하게 이해할 것이다. 예를 들어, 2'-OH 당 모이어티 및 티민 염기를 포함하는 뉴클레오사이드를 포함하는 올리고뉴클레오타이드는 변형된 당을 갖는 DNA(DNA의 하나의 2'-H 대신에 2'-OH)로서 또는 변형된 염기를 갖는 RNA(RNA의 유라실 대신에 티민(메틸화된 유라실))로서 기재될 수 있다. 따라서, 서열 목록에서의 것(이들로 제한되지 않음)을 포함하는 본 명세서에 제공된 핵산 서열은 천연 또는 변형된 RNA 및/또는 DNA, 예를 들어 변형된 핵염기를 갖는 이러한 핵산(이들로 제한되지 않음)의 임의의 조합을 함유하는 핵산을 포함하도록 의도된다. 추가의 예의 방식으로, 비제한적으로, 핵염기 서열 "ATCGATCG"를 갖는 올리고머 화합물은, 변형되든 또는 비변형되든, 이러한 핵염기 서열을 갖는 임의의 올리고머 화합물, 예를 들어, RNA 염기를 포함하는 이러한 화합물, 예컨대, 서열 "AUCGAUCG"를 갖는 것 및 몇몇 DNA 염기 및 몇몇 RNA 염기를 갖는 것, 예컨대, "AUCGATCG" 및 다른 변형된 핵염기를 갖는 올리고머 화합물, 예컨대, "ATmCGAUCG"(여기서, mC는 5-위치에서 메틸기를 포함하는 사이토신 염기를 나타냄)(이들로 제한되지 않음)을 포함한다.
본 명세서에 기재된 특정 화합물(예를 들어, 변형된 올리고뉴클레오타이드)은 하나 이상의 비대칭 중심을 갖고, 이에 따라 (R) 또는 (S)로서, 예컨대, 당 아노머에 대해 α 또는 β로서, 또는 예컨대, 아미노산 등에 대해 (D) 또는 (L)로서 절대 입체화학과 관련하여 한정될 수 있는 거울상이성질체, 부분입체이성질체 및 다른 입체이성질체 배위를 발생시킨다. 특정 입체이성질체 배위를 갖는 것으로 도시되거나 기재된 본 명세서에 제공된 화합물은 제시된 화합물 만을 포함한다. 비한정된 입체화학에 의해 도시되거나 기재된 본 명세서에 제공된 화합물은, 달리 기재되지 않는 한, 모든 이러한 가능한 이성질체, 예를 들어, 이의 입체무작위 및 광학적으로 순수한 형태를 포함한다. 마찬가지로, 달리 표시되지 않는 한 본 명세서에서 화합물의 호변이성질체 형태가 또한 포함된다. 달리 제시되지 않는 한, 본 명세서에 기재된 화합물은 상응하는 염 형태를 포함하도록 의도된다.
본 명세서에 기재된 화합물은 하나 이상의 원자가 표시된 원소의 비방사성 동위원소 또는 방사성 동위원소에 의해 대체된 변동을 포함한다. 예를 들어, 수소 원자를 포함하는 본 명세서에서 화합물은 각각의 1H 수소 원자에 대해 모든 가능한 중수소 치환을 포함한다. 본 명세서에서 화합물에 의해 포함된 동위원소 치환은 1H 대신에 2H 또는 3H, 12C 대신에 13C 또는 14C, 14N 대신에 15N, 16O 대신에 17O 또는 18O 및 32S 대신에 33S, 34S, 35S 또는 36S를 포함하지만, 이들로 제한되지 않는다. 특정 실시형태에서, 비방사성 동위원소 치환은 치료적 또는 연구 도구로서 사용하기에 유리한 올리고머 화합물에서 새로운 특성을 부여할 수 있다. 특정 실시형태에서, 방사성 동위원소 치환은 조사 또는 진단 목적, 예컨대, 영상화에 적합한 화합물을 만들 수 있다.
실시예
하기 실시예는 본 개시내용의 특정 실시형태를 예시하고, 제한이 아니다. 더구나, 구체적인 실시형태가 제공될 때, 본 발명자들은 이 구체적인 실시형태의 포괄적인 적용을 고려한다. 예를 들어, 특정 모티프를 갖는 올리고뉴클레오타이드의 개시내용이 동일하거나 유사한 모티프를 갖는 추가적인 올리고뉴클레오타이드에 대한 합당한 지원을 제공한다. 그리고, 예를 들어 특정 고친화도 변형이 특정 위치에서 나타날 때, 달리 표시되지 않는 다른 동일한 위치에서의 고친화도 변형은 적합하다고 간주된다.
실시예 1: 시험관내에서 인간 UBE3A-ATS RNA에 대한 5-10-5 MOE 갭머 변형된 올리고뉴클레오타이드의 효과, 단일 용량
인간 UBE3A-ATS 핵산과 상보성인 변형된 올리고뉴클레오타이드를 시험관내에서 UBE3A-ATS RNA 수준에 대한 효과에 대해서 시험하였다.
하기 표의 변형된 올리고뉴클레오타이드는 5-10-5 MOE 갭머이다. 이러한 갭머는 20개 뉴클레오사이드 길이이고, 여기서 중심 캡 분절은 10개의 2'-β-D-데옥시뉴클레오사이드로 이루어지고, 5' 윙 분절 및 3' 윙 분절은 각각 5개의 2'-MOE 뉴클레오사이드로 이루어진다. 갭머에 대한 당 모티프는 (5'에서 3'로): eeeeeddddddddddeeeee이고; 식 중, 'd'는 2'-β-D-데옥시리보실 당 모이어티를 나타내고, 'e'는 2'-MOE 당 모이어티를 나타낸다.
(표 2 및 표 3에서) 화합물 ID 617441 내지 617596의 각각의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이다. 모든 다른 화합물(표 4 내지 표 33)은 (5'에서 3'로) soooossssssssssooss의 뉴클레오사이드간 링키지 모티프를 갖고; 식 중, 각각의 "s"는 포스포로티오에이트 뉴클레오사이드간 링키지를 나타내고, 각각의 "o"는 포스포다이에스터 뉴클레오사이드간 링키지를 나타낸다.
모든 사이토신 잔기는 5-메틸사이토신이다.
"시작 부위"는 변형된 올리고뉴클레오타이드가 인간 유전자 서열에서 상보성인 5'-가장 가까운 뉴클레오사이드를 나타낸다. "종결 부위"는 변형된 올리고뉴클레오타이드가 표적 핵산 서열에서 상보성인 3'-가장 가까운 뉴클레오사이드를 나타낸다. 하기 표에 열거된 각각의 변형된 올리고뉴클레오타이드는 서열번호 1(뉴클레오타이드 24821647 내지 25441028로부터 절두된 진뱅크 수탁 번호 NC_000015.10)과 100% 상보성이다. 하기 표의 선택된 화합물은 3개 초과의 특정 부위에서 표적 핵산 서열과 상보성이다. 이들 화합물의 경우, 하기 표의 "시작 부위" 및 "종결 부위" 값은 해시태그(#)로 표현되며, 그 화합물이 상보성인 첫 번째 부위만을 나타낸다. 이들 화합물이 상보성인 추가 부위를 하기 표 4b에 나타낸다.
인간 IPSC 세포 유래된 iCell GABANeurons(셀룰러 다이나믹스사(Cellular Dynamics))를 웰당 20,000 내지 60,000개 세포로 제조사 설명서에 따라서 배양하고(표 제목에 제시된 바와 같음), 자유 흡수에 의해서 5,000 내지 10,000nM의 변형된 올리고뉴클레오타이드(표 제목에 제시된 바와 같음)로 처리하였다. 대략 6일의 처리 시간 후, 총 RNA를 세포로부터 단리시키고, UBE3A-ATS RNA 수준을 정량적 실시간 RTPCR로 측정하였다. 인간 UBE3A-ATS 프라이머 프로브 세트 RTS4796(정방향 서열 CTCCCCCAGTTCTGGAATGA, 본 명세서에서 서열번호 2라고 지정; 역방향 서열 TACACAGGGATTTGAGCCTGCTA, 본 명세서에서 서열번호 3이라고 지정; 프로브 서열 CCCACAGATCAAGCATTCCCCAAAGA, 본 명세서에서 서열번호 4라고 지정)을 사용하여 RNA 수준을 측정하였다. UBE3A-ATS RNA 수준을 RIBOGREEN®에 의해서 측정된 바와 같이 총 RNA 함량에 대해서 정규화시켰다. UBE3A-ATS RNA의 감소를 미처리 대조군(untreated control: UTC) 세포에 대한 UBE3A-ATS RNA 양의 백분율로서 하기 표에 제시한다. 각각의 표는 개별 검정 플레이트로부터의 결과를 나타낸다. 별표(*)로 표시된 값은 변형된 올리고뉴클레오타이드가 프라이머 프로브 세트의 앰플리콘 영역과 상보성이라는 것을 나타낸다. 추가 검정을 사용하여 앰플리콘 영역에 상보성인 변형된 올리고뉴클레오타이드의 효력 및 효능을 측정하였다. "N.D."는 그 값이 실험 오류로 인해서 본 실험에서 결정되지 않았다는 것을 나타낸다. 그러나, 실시예 1에 정의되지 않은 것을 포함하여, 선택된 변형된 올리고뉴클레오타이드의 활성은 하기 본 명세서에서 용량-반응 연구에서 성공적으로 입증된다.
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[표 4b]
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실시예 2: 시험관내에서 인간 UBE3A-ATS RNA에 대한 5-10-5 MOE 갭머 변형된 올리고뉴클레오타이드의 효과, 단일 용량
인간 UBE3A-ATS 핵산과 상보성인 변형된 올리고뉴클레오타이드를 시험관내에서 UBE3A-ATS RNA 수준에 대한 효과에 대해서 시험하였다.
하기 표의 변형된 올리고뉴클레오타이드는 5-10-5 갭머이다. 이러한 갭머는 20개 뉴클레오사이드 길이이고, 여기서 중심 캡 분절은 10개의 2'-β-D-데옥시뉴클레오사이드로 이루어지고, 5' 윙 분절 및 3' 윙 분절은 각각 5개의 2'-MOE 뉴클레오사이드로 이루어진다. 갭머에 대한 당 모티프는 (5'에서 3'로): eeeeeddddddddddeeeee이고; 식 중, 'd'는 2'-β-D-데옥시리보실 당 모이어티를 나타내고, 'e'는 2'-MOE 당 모이어티를 나타낸다.
화합물 ID 617456, 617457, 617460, 617461 및617557의 각각의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이다. 모든 다른 화합물은 soooossssssssssooss의 뉴클레오사이드간 링키지 모티프를 갖고, 식 중, 각각의 "s"는 포스포로티오에이트 뉴클레오사이드간 링키지를 나타내고, "o"는 포스포다이에스터 뉴클레오사이드간 링키지를 나타낸다.
모든 사이토신 잔기는 5-메틸사이토신이다.
"종결 부위"는 변형된 올리고뉴클레오타이드가 표적 핵산 서열에서 상보성인 5'-가장 가까운 뉴클레오사이드를 나타낸다. "종결 부위"는 변형된 올리고뉴클레오타이드가 표적 핵산 서열에서 상보성인 3'-가장 가까운 뉴클레오사이드를 나타낸다. 하기 표에 열거된 각각의 변형된 올리고뉴클레오타이드는 서열번호 1과 100% 상보성이다. 화합물 750519에 대한 시작 부위 및 종결 부위를 하기 몇몇 표에 해시태그(#)로 표시한다. 화합물 750519에 대한 시작 부위의 완전한 목록을 표 4b에 열거한다.
인간 IPS 세포 유래된 ReproNeuro™ Neurons(레프로셀사(ReproCELL))를 웰당 40,000개 셀로 제조사 설명서에 따라서 배양하고, 자유 흡수에 의해서 8,000nM의 변형된 올리고뉴클레오타이드로 처리하였다. 대략 5일의 처리 시간 후, 총 RNA를 세포로부터 단리시키고, UBE3A-ATS RNA 수준을 정량적 실시간 RTPCR로 측정하였다. 인간 UBE3A-ATS 프라이머 프로브 세트 RTS4796(본 명세서 실시예 1에 기재됨)을 사용하여 RNA 수준을 측정하였다. UBE3A-ATS RNA 수준을 RIBOGREEN®에 의해서 측정된 바와 같이 총 RNA 함량에 대해서 정규화시켰다. UBE3A-ATS의 감소를 미처리 대조군(UTC) 세포에 대한 UBE3A-ATS RNA 양의 백분율로서 하기 표에 제시한다. 각각의 표는 개별 검정 플레이트로부터의 결과를 나타낸다. 별표(*)로 표시된 값은 변형된 올리고뉴클레오타이드가 프라이머 프로브 세트의 앰플리콘 영역과 상보성이라는 것을 나타낸다. 추가 검정을 사용하여 앰플리콘 영역에 상보성인 변형된 올리고뉴클레오타이드의 효력 및 효능을 측정하였다.
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실시예 3: 시험관내에서 인간 UBE3A-ATS RNA에 대한 5-10-5 MOE 갭머 변형된 올리고뉴클레오타이드의 효과, 단일 용량
인간 UBE3A-ATS 프라이머 프로브 세트 LTS01075(정방향 서열 GCCCGAAGTGCCTATTCCTT, 본 명세서에서 서열번호 5라고 지정됨; 역방향 서열 TGGTCAGGAGAACATAGGCATAAA, 본 명세서에서 서열번호 6이라고 지정됨; 프로브 서열 ACTCCCAGGGTTGATGGGCTACATCC, 본 명세서에서 서열번호 7이라고 지정됨)를 사용하여 RNA 수준을 측정한 것을 제외하고는, 본질적으로 실시예 1에 기재된 바와 같이, 인간 UBE3A-ATS 핵산과 상보성인 변형된 올리고뉴클레오타이드를 시험관내에서 UBE3A-ATS RNA 수준에 대한 효과에 대해서 시험하였다.
하기 표의 변형된 올리고뉴클레오타이드는 5-10-5 갭머이다. 이러한 갭머는 20개 뉴클레오사이드 길이이고, 여기서 중심 캡 분절은 10개의 2'-β-D-데옥시뉴클레오사이드로 이루어지고, 3' 윙 분절 및 5' 윙 분절은 각각 5개의 2'-MOE 뉴클레오사이드로 이루어진다. 갭머에 대한 당 모티프는 (5'에서 3'로): eeeeeddddddddddeeeee이고; 식 중, 'd'는 2'-β-D-데옥시리보실 당 모이어티를 나타내고, 'e'는 2'-MOE 당 모이어티를 나타낸다. 화합물 ID 617456, 617457, 617460, 617461 및617557의 각각의 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지이다. 모든 다른 화합물은 soooossssssssssooss의 뉴클레오사이드간 링키지 모티프를 갖고, 식 중, 각각의 "s"는 포스포로티오에이트 뉴클레오사이드간 링키지를 나타내고, "o"는 포스포다이에스터 뉴클레오사이드간 링키지를 나타낸다.
모든 사이토신 잔기는 5-메틸사이토신이다.
"시작 부위"는 변형된 올리고뉴클레오타이드가 표적 핵산에서 상보성인 5'-가장 가까운 뉴클레오사이드를 나타낸다. "종결 부위"는 변형된 올리고뉴클레오타이드가 표적 핵산에서 상보성인 3'-가장 가까운 뉴클레오사이드를 나타낸다. 하기 표에 열거된 각각의 변형된 올리고뉴클레오타이드는 서열번호 1과 100% 상보성이다.
UBE3A-ATS RNA의 감소를 미처리 대조군(UTC) 세포에 대한 UBE3A-ATS RNA 양의 백분율로서 하기 표에 제시한다. 별표(*)로 표시된 값은 변형된 올리고뉴클레오타이드가 프라이머 프로브 세트의 앰플리콘 영역과 상보성이라는 것을 나타낸다. 추가 검정을 사용하여 앰플리콘 영역에 상보성인 변형된 올리고뉴클레오타이드의 효력 및 효능을 측정하였다.
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실시예 4: 시험관내에서 인간 UBE3A-ATS RNA에 대한 변형된 올리고뉴클레오타이드의 효과, 다회 용량
상기 실시예로부터 선택된 변형된 올리고뉴클레오타이드를 인간 IPS 유래된 iCell GABANeurons(셀러 다이나믹스사(Cellular Dynamics))에서 다양한 용량에서 시험하였다. 세포를 35,000 내지 60,000개 세포/웰의 밀도로 플레이팅하고, 제조사 설명서에 따라서 유지시키고, 하기 표에 명시된 바와 같이, 다양한 농도에서, 자유 흡수에 의해서 변형된 올리고뉴클레오타이드로 처리하였다. 대략 6일의 처리 시간 후, 총 RNA를 세포로부터 단리시키고, UBE3A-ATS RNA 수준을 정량적 실시간 PCR로 측정하였다. 상기에 기재된 인간 UBE3A-ATS 프라이머 프로브 세트 RTS4796을 사용하여 RNA 수준을 측정하였다. UBE3A-ATS RNA 수준을 RIBOGREEN®에 의해서 측정된 바와 같이 총 RNA 함량에 따라서 정규화시켰다. UBE3A-ATS RNA의 감소를 미처리 대조군(UTC) 세포에 대한 UBE3A-ATS RNA 양의 백분율로서 하기 표에 제시한다.
가능한 경우, 변형된 올리고뉴클레오타이드의 반치 최대 저해 농도(half maximal inhibitory concentration)(IC50)를 엑셀에서 데이터의 로그/선형 플롯 상의 선형 회귀를 사용하여 계산하였다. 일부 경우에, IC50은 신뢰할 수 있게 계산될 수 없었고, 이 데이터 지점은 "N.C."로서 표현된다. "N.D."로 표현된 값은 값이 본 실험에서 결정되지 않았다는 것을 나타낸다.
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실시예 5: 시험관내에서 인간 UBE3A-ATS RNA에 대한 변형된 올리고뉴클레오타이드의 효과, 다회 용량
상기 실시예로부터 선택된 변형된 올리고뉴클레오타이드를 인간 IPS 유래된 ReproNeuro™ Neurons(레프로셀사(ReproCELL))에서 다양한 용량에서 시험하였다. 세포를 20,000개 세포/웰의 밀도로 플레이팅하고, 제조사 설명서에 따라서 유지시키고, 하기 표에 명시된 바와 같이, 다양한 농도에서, 자유 흡수에 의해서 변형된 올리고뉴클레오타이드로 처리하였다. 대략 5일의 처리 시간 후, 총 RNA를 세포로부터 단리시키고, UBE3A-ATS RNA 수준을 정량적 실시간 PCR로 측정하였다. 상기에 기재된 인간 UBE3A-ATS 프라이머 프로브 세트 RTS4796을 사용하여 RNA 수준을 측정하였다. UBE3A-ATS RNA 수준을 RIBOGREEN®에 의해서 측정된 바와 같이 총 RNA 함량에 따라서 정규화시켰다. UBE3A-ATS RNA의 감소를 미처리 대조군(UTC) 세포에 대한 UBE3A-ATS RNA 양의 백분율로서 하기 표에 제시한다.
변형된 올리고뉴클레오타이드의 반치 최대 저해 농도(IC50)를 엑셀에서 데이터의 로그/선형 플롯 상의 선형 회귀를 사용하여 계산하였다. IC50를 계산할 수 없는 경우, IC50을 N.C.(계산되지 않음)라고 표현한다.
Figure pct00130
실시예 6: 시험관내에서 인간 UBE3A-ATS RNA 및 UBE3A RNA에 대한 변형된 올리고뉴클레오타이드의 효과, 다회 용량
상기 실시예로부터 선택된 변형된 올리고뉴클레오타이드를 안젤만 증후군 환자 유래된 IPS 세포로부터 유래된 10주 분화된 인간 뉴런 세포(문헌[Chamberlain SJ., et al., Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader-Willi syndromes. PNAS, 2010. 41: 17668-17673]에 기재된 프로토콜 및 세포)에서 다양한 용량으로 시험하였다. 10주 분화 기간 후에, 세포를 하기 표에 명시된 바와 같이, 다양한 농도에서, 자유 흡수에 의해서 변형된 올리고뉴클레오타이드로 처리하였다. 대략 6일의 처리 시간 후, 총 RNA를 세포로부터 단리시켰다. UBE3A-ATS RNA 및 UBE3A RNA 수준 둘 다를 정량적 실시간 PCR에 의해서 측정하였다. 인간 UBE3A-ATS 프라이머 프로브 세트 RTS4796을 사용하여 상기에 기재된 바와 같이 UBE3A-ATS RNA 수준을 측정하였다. 인간 UBE3A 프라이머 세트 RTS35984(정방향 서열 CACCCTGATGTCACCGAATG, 본 명세서에서 서열번호 8이라고 지정됨; 역방향 서열 GCGTTCTATTAGATGCTTTGCAG, 본 명세서에서 서열번호 9라고 지정됨; 프로브 서열 ACTGAGGTTCTCCTGATCTTTTACAAGCTG, 본 명세서에서 서열번호 10이라고 지정됨)를 사용하여 UBE3A RNA 수준을 측정하였다. RNA 수준을 RIBOGREEN®에 의해서 측정된 바와 같이 총 RNA 함량에 따라서 조정하였다. UBE3A-ATS RNA의 감소 및 UBE3A RNA의 유도를 미처리 대조군(UTC) 세포에 대한 UBE3A-ATS RNA 양의 백분율 또는 UBE3A RNA 백분율로서 하기 표에 제시한다. "N.D."로 표현된 값은 값이 본 실험에서 결정되지 않았다는 것을 나타낸다.
몇몇 변형된 올리고뉴클레오타이드는 안젤만 환자 IPS 세포 유래된 뉴런에서 UBE3A RNA의 동시 증가와 함께 UBE3A-ATS RNA를 감소시키는 것을 발견하였다.
Figure pct00131
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실시예 7: 인간 UBE3A-ATS 핵산과 상보성인 변형된 올리고뉴클레오타이드의 설계 및 합성
변형된 올리고뉴클레오타이드를 하기 표에 제시된 바와 같이 합성하였다.
표 62의 화합물은 4-10-6 MOE 갭머이다. 갭머는 20개 뉴클레오사이드 길이이고, 여기서 중심 갭 분절은 10개의 2'-β-D-데옥시뉴클레오사이드로 이루어지고, 5' 윙 분절은 4개의 2'-MOE 뉴클레오사이드로 이루어지며, 3' 윙 분절은 6개의 2'-MOE 뉴클레오사이드로 이루어진다. 갭머의 당 모티프는 (5'에서 3'로) eeeeddddddddddeeeeee이고; 식 중, 'd'는 2'-β-D-데옥시리복실 당 모이어티를 나타내고, 'e'는 2'-MOE 당 모이어티를 나타낸다. 갭머는 (5'에서 3'로) sooossssssssssoooss의 뉴클레오사이드간 링키지 모티프를 갖고; 식 중, "s"는 포스포로티오에이트 뉴클레오사이드간 링키지를 나타내고, "o"는 포스포다이에스터 뉴클레오사이드간 링키지를 나타낸다. 모든 사이토신 잔기는 5-메틸사이토신이다.
Figure pct00138
Figure pct00139
표 63의 화합물은 5-10-5 MOE 갭머이다. 이러한 갭머는 20개 뉴클레오사이드 길이이고, 여기서 중심 캡 분절은 10개의 2'-β-D-데옥시리보뉴클레오사이드로 이루어지고, 5' 윙 분절 및 3' 윙 분절은 각각 5개의 2'-MOE 뉴클레오사이드로 이루어진다. 갭머에 대한 당 모티프는 (5'에서 3'로) eeeeeddddddddddeeeee이고; 식 중, 'd'는 2'-β-D-데옥시리보실 당 모이어티를 나타내고, 'e'는 2'-MOE 당 모이어티를 나타낸다. 갭머는 (5'에서 3'로) soooossssssssssooss의 뉴클레오사이드간 링키지 모티프를 갖고, 식 중, "s"는 포스포로티오에이트 뉴클레오사이드간 링키지를 나타내고, "o"는 포스포다이에스터 뉴클레오사이드간 링키지를 나타낸다. 모든 사이토신 잔기는 5-메틸사이토신이다.
Figure pct00140
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표 64의 화합물은 6-10-4 MOE 갭머이다. 갭머는 20개 뉴클레오사이드 길이이고, 여기서 중심 갭 분절은 10개의 2'-β-D-데옥시뉴클레오사이드로 이루어지고, 5' 윙 분절은 6개의 2'-MOE 뉴클레오사이드로 이루어지며, 3' 윙 분절은 4개의 2'-MOE 뉴클레오사이드로 이루어진다. 갭머의 당 모티프는 (5'에서 3'로) eeeeeeddddddddddeeee이고; 식 중, 'd'는 2'-β-D-데옥시리복실 당 모이어티를 나타내고, 'e'는 2'-MOE 당 모이어티를 나타낸다. 갭머는 (5'에서 3'로) sooooossssssssssoss의 뉴클레오사이드간 링키지 모티프를 갖고; 식 중, "s"는 포스포로티오에이트 뉴클레오사이드간 링키지를 나타내고, "o"는 포스포다이에스터 뉴클레오사이드간 링키지를 나타낸다. 모든 사이토신 잔기는 5-메틸사이토신이다.
Figure pct00144
Figure pct00145
표 65의 화합물은 4-8-6 MOE 갭머이다. 갭머는 18개 뉴클레오사이드 길이이고, 여기서 중심 갭 분절은 8개의 2'-β-D-데옥시뉴클레오사이드로 이루어지고, 5' 분절은 4개의 2'-MOE 뉴클레오사이드로 이루어지며, 3' 윙 분절은 6개의 2'-MOE 뉴클레오사이드로 이루어진다. 갭머의 당 모티프는 (5'에서 3'로) eeeeddddddddeeeeee이고; 식 중, 'd'는 2'-β-D-데옥시리복실 당 모이어티를 나타내고, 'e'는 2'-MOE 당 모이어티를 나타낸다. 갭머는 (5'에서 3'로) soosssssssssoooss의 뉴클레오사이드간 링키지 모티프를 갖고; 식 중, "s"는 포스포로티오에이트 뉴클레오사이드간 링키지를 나타내고, "o"는 포스포다이에스터 뉴클레오사이드간 링키지를 나타낸다. 모든 사이토신 잔기는 5-메틸사이토신이다.
Figure pct00146
표 66의 화합물은 5-8-5 MOE 갭머이다. 이러한 갭머는 18개 뉴클레오사이드 길이이고, 여기서 중심 캡 분절은 8개의 2'-β-D-데옥시뉴클레오사이드로 이루어지고, 5' 윙 분절 및 3' 윙 분절은 각각 5개의 2'-MOE 뉴클레오사이드로 이루어진다. 갭머의 당 모티프는 (5'에서 3'로) eeeeeddddddddeeeee이고; 식 중, 'd'는 2'-β-D-데옥시리복실 당 모이어티를 나타내고, 'e'는 2'-MOE 당 모이어티를 나타낸다. 갭머는 (5'에서 3'로) sooosssssssssooss의 뉴클레오사이드간 링키지 모티프를 갖고; 식 중, "s"는 포스포로티오에이트 뉴클레오사이드간 링키지를 나타내고, "o"는 포스포다이에스터 뉴클레오사이드간 링키지를 나타낸다. 모든 사이토신 잔기는 5-메틸사이토신이다.
Figure pct00147
표 67의 화합물은 6-8-4 MOE 갭머이다. 갭머는 18개 뉴클레오사이드 길이이고, 여기서 중심 갭 분절은 8개의 2'-β-D-데옥시뉴클레오사이드로 이루어지고, 5' 윙 분절은 6개의 2'-MOE 뉴클레오사이드로 이루어지며, 3' 윙 분절은 4개의 2'-MOE 뉴클레오사이드로 이루어진다. 갭머의 당 모티프는 (5'에서 3'로) eeeeeeddddddddeeee이고; 식 중, 'd'는 2'-β-D-데옥시리복실 당 모이어티를 나타내고, 'e'는 2'-MOE 당 모이어티를 나타낸다. 갭머는 (5'에서 3'로) soooosssssssssoss의 뉴클레오사이드간 링키지 모티프를 갖고; 식 중, "s"는 포스포로티오에이트 뉴클레오사이드간 링키지를 나타내고, "o"는 포스포다이에스터 뉴클레오사이드간 링키지를 나타낸다. 모든 사이토신 잔기는 5-메틸사이토신이다.
Figure pct00148
실시예 8: 시험관내에서 인간 UBE3A-ATS RNA에 대한 변형된 올리고뉴클레오타이드의 효과, 다회 용량
상기 실시예로부터 선택된 변형된 올리고뉴클레오타이드를 실시예 4에 기재된 바와 같이, 인간 IPS 유래된 iCell GABANeurons(셀러 다이나믹스사(Cellular Dynamics))에서 다양한 용량에서 시험하였다. UBE3A-ATS RNA의 감소를 미처리 대조군(UTC) 세포에 대한 UBE3A-ATS RNA 양의 백분율로서 하기 표에 제시한다. 가능한 경우, 변형된 올리고뉴클레오타이드의 반치 최대 저해 농도(IC50)를 엑셀에서 데이터의 로그/선형 플롯 상의 선형 회귀를 사용하여 계산하였다. 일부 경우에, IC50은 신뢰할 수 있게 계산될 수 없었고, 이 데이터 지점은 "N.C."로서 표현된다. "N.D."로 표현된 값은 값이 본 실험에서 결정되지 않았다는 것을 나타낸다.
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실시예 9: 시험관내에서 인간 UBE3A-ATS RNA 및 UBE3A RNA에 대한 변형된 올리고뉴클레오타이드의 효과, 다회 용량
상기 실시예로부터 선택된 변형된 올리고뉴클레오타이드를 상기 실시예 6에 기재된 바와 같이 안젤만 증후군 환자 유래된 IPS 세포로부터 유래된 10주 분화된 인간 뉴런 세포에서 다양한 용량으로 시험하였다. UBE3A-ATS RNA의 감소 및 UBE3A RNA의 유도를 미처리 대조군(UTC) 세포에 대한 UBE3A-ATS RNA 양의 백분율 또는 UBE3A RNA 백분율로서 하기 표에 제시한다. "N.D."로 표현된 값은 값이 본 실험에서 결정되지 않았다는 것을 나타낸다.
몇몇 변형된 올리고뉴클레오타이드는 안젤만 환자 IPS 세포 유래된 뉴런에서 UBE3A RNA의 동시 증가와 함께 UBE3A-ATS RNA를 감소시키는 것을 발견하였다.
Figure pct00155
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실시예 10: 야생형 마우스에서 인간 UBE3A-ATS와 상보성인 변형된 올리고뉴클레오타이드의 내약성 3시간 연구
상기에 기재된 변형된 올리고뉴클레오타이드를 야생형 암컷 C57/Bl6 마우스에서 시험하여 올리고뉴클레오타이드의 내약성을 평가하였다. 야생형 암컷 C57/Bl6 마우스 각각에게 하기 표에 열거된 변형된 올리고뉴클레오타이드 700㎍ 단일 ICV 용량을 제공하였다. 각각의 처리군은 4마리 마우스로 이루어졌다. 4마리 마우스의 군에게 각각의 실험에 대한 음성 대조군으로서 PBS를 제공하였다(하기 별개의 표에 식별됨). 주사 3시간 후에, 마우스를 7가지의 상이한 기준에 따라서 평가하였다. 기준은 (1) 마우스가 명랑하고, 기민하고, 반응성이었는지; (2) 마우스가 자극 없이 서 있거나, 웅크리고 있었는지; (3) 마우스가 자극 없이 임의의 움직임을 나타내었는지; (4) 마우스를 들어 올린 후 마우스가 앞쪽으로 움직였는지; (5) 마우스를 들어 올린 후 임의의 움직임을 나타내었는지; (6) 마우스가 꼬리 꼬집음에 반응하였는지; (7) 규칙적으로 호흡하였는지이다. 7가지 기준 각각에 대해서, 마우스가 그 기준을 충족하면 0의 하위 점수를 제공하고, 충족하지 않으면 1을 제공하였다(기능적 관찰 배터리 점수 또는 FOB). 모든 7개의 기준을 평가한 후, 점수를 각각의 마우스에 대해서 합하고, 각각의 처리군에서 평균내었다. 결과를 하기 표에 제공한다.
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실시예 11: 래트에서 인간 UBE3A-ATS와 상보성인 변형된 올리고뉴클레오타이드의 내약성, 3시간 연구
상기에 기재된 변형된 올리고뉴클레오타이드를 래트에서 시험하여 올리고뉴클레오타이드의 내약성을 평가하였다. 스프라그 돌리 래트 각각에게 하기 표에 열거된 올리고뉴클레오타이드 3㎎의 척추강내(IT) 용량을 제공하였다. 각각의 처리군은 4마리 래트로 이루어졌다. 4마리 래트의 군에게 음성 대조군으로서 PBS를 제공하였다. 주사 3시간 후에, 신체의 7개의 상이한 부분의 움직임을 각각의 래트에서 평가하였다. 7개의 신체 부분은 (1) 래트의 꼬리; (2) 래트의 후방 부위; (3) 래트의 뒷다리; (4) 래트의 뒷발; (5) 래트의 앞발; (6) 래트의 전방 부위; (7) 래트의 머리이다. 7개의 상이한 신체 부분 각각에 대해서, 신체 부분이 움직이면 0의 하위 점수를 제공하거나, 신체 부분이 마비되면 1을 제공하였다(기능적 관찰 배터리 점수 또는 FOB). 7개의 신체 부분 각각을 평가한 후, 하위 점수를 각각의 래트에 대해서 합하고, 각각의 군에 대해서 평균내었다. 예를 들어, 래트의 꼬리, 머리 및 모든 다른 평가된 신체 부분이 3㎎ IT 용량 3시간 후에 움직이면, 그것은 0의 합한 점수를 가질 것이다. 또 다른 래트가 3㎎ IT 용량 3시간 후에 꼬리를 움직이지 않았지만, 모든 다른 평가된 신체 부분이 움직였으면, 그것은 1의 점수를 가질 것이다. 결과를 각각의 처리군에 대한 평균 점수로 제시한다.
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실시예 12: 야생형 마우스에서 인간 UBE3A-ATS와 상보성인 변형된 올리고뉴클레오타이드의 내약성, 2주 연구
상기에 기재된 변형된 올리고뉴클레오타이드를 야생형 암컷 C57/Bl6 마우스에서 시험하여 올리고뉴클레오타이드의 내약성을 평가하였다. 야생형 암컷 C57/Bl6 마우스 각각에게 하기 표에 열거된 변형된 올리고뉴클레오타이드 700㎍ 단일 ICV 용량을 제공하였다. 각각의 처리군은 4마리 마우스로 이루어졌다. 4마리 마우스의 군에게 각각의 실험에 대한 음성 대조군으로서 PBS를 제공하였다(하기 별개의 표에 식별됨). 주사 2주 후에, 마우스를 7가지의 상이한 기준에 따라서 평가하였다. 기준은 (1) 마우스가 명랑하고, 기민하고, 반응성이었는지; (2) 마우스가 자극 없이 서 있거나, 웅크리고 있었는지; (3) 마우스가 자극 없이 임의의 움직임을 나타내었는지; (4) 마우스를 들어 올린 후 마우스가 앞쪽으로 움직였는지; (5) 마우스를 들어 올린 후 임의의 움직임을 나타내었는지; (6) 마우스가 꼬리 꼬집음에 반응하였는지; (7) 규칙적으로 호흡하였는지이다. 7가지 기준 각각에 대해서, 마우스가 그 기준을 충족하면 0의 하위 점수를 제공하고, 충족하지 않으면 1을 제공하였다(기능적 관찰 배터리 점수 또는 FOB). 모든 7개의 기준을 평가한 후, 점수를 각각의 마우스에 대해서 합하고, 각각의 처리군에서 평균내었다. 결과를 하기 표에 제공한다.
Figure pct00197
실시예 13: 트랜스제닉 마우스에서 인간 UBE3A-ATS와 상보성인 변형된 올리고뉴클레오타이드의 활성
상기에 기재된 변형된 올리고뉴클레오타이드를 UBE3A-ATS BAC 트랜스제닉 마우스 모델에서 시험하였다. 트랜스제닉 마우스 모델을 미시간 대학 박테리아 인공 염색체 재조합 코어(University of Michigan Bacterial Artificial Chromosome Recombineering Core)에서 개발하였고, 이것은 (BAC 클론 RP11-664B13으로부터) 인간 염색체 15(GRCh38/hg38 어셈블리)로부터의 영역 25163935-25348867을 함유한다. UBE3A-ATS 발현은 ENO2 프로모터에 의해서 유도되며, BGH poly(A) 신호로 종결된다. 유전자 분절을 전핵 주사에 의해 C57BL/6 마우스로부터의 수정란에 도입하여 하기에 기재된 실험에 사용되는 주 RP11-748을 생성시켰다.
처리
UBE3A-ATS 트랜스제닉 마우스를 각각 2 내지 4마리 마우스의 군으로 나누었다. 각각의 마우스에게 350㎍의 변형된 올리고뉴클레오타이드의 단일 ICV 볼러스(bolus)를 제공하였다. 4마리 마우스의 군에게 음성 대조군으로서 PBS를 제공하였다.
RNA 분석
2주 후, 마우스를 희생시키고, 프라이머 프로브 세트 RTS4796(본 명세서 상기에 기재됨) 및/또는 프라이머 프로브 세트 RTS40595(정방향 서열 TCCTTCCCTACCTTAGTCTTGA, 본 명세서에서 서열번호 14라고 지정됨; 역방향 서열 CCCTCTTGAACCAGGAAACA, 본 명세서에서 서열번호 15라고 지정됨; 프로브 서열 AGATGGCAGCCCACATTTCTACTGT, 본 명세서에서 서열번호 16이라고 지정됨)를 사용하여 UBE3A-ATS의 RNA 발현의 측정의 실시간 PCR 분석을 위해서 피질 뇌 조직, 해마 뇌 조직 및 척수로부터 RNA를 추출하였다. 프라이머 프로브 세트 RTS4796은 올리고뉴클레오타이드가 프라이머 프로브 결합 부위로부터 먼 부위에 결합하는 경우 덜 신뢰할 만하다. 결과를 마우스 GAPDH에 정규화된, PBS 대조군에 대한 RNA의 백분율 변화로서 제공한다. 마우스 GAPDH를 프라이머 프로브 세트 RTS108(정방향 서열 GGCAAATTCAACGGCACAGT, 본 명세서에서 서열번호 11이라고 지정됨; 역방향 서열 GGGTCTCGCTCCTGGAAGAT, 본 명세서에서 서열번호 12라고 지정됨; 프로브 서열 AAGGCCGAGAATGGGAAGCTTGTCATC, 본 명세서에서 서열번호 13이라고 지정됨)를 사용하여 증폭시켰다. 일부 경우에, RTPCR 값은 특정 샘플에 대해서 정의되지 않으며, N.D.(정의되지 않음)라고 표지한다.
하기 표에 나타낸 바와 같이, 변형된 올리고뉴클레오타이드를 사용한 처리는 PBS 대조군에 비해서 UBE3A-ATS RNA의 감소를 초래하였다.
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실시예 14: 트랜스제닉 마우스에서 인간 UBE3A-ATS와 상보성인 변형된 올리고뉴클레오타이드의 활성, 다회 용량
상기에 기재된 변형된 올리고뉴클레오타이드를 UBE3A-ATS BAC 트랜스제닉 마우스 모델 RP11-748 주에서 시험하였다.
처리
UBE3A-ATS 트랜스제닉 마우스를 각각 3마리 마우스의 군으로 나누었다. 각각의 마우스에게 10, 30, 100, 300 또는 700㎍의 변형된 올리고뉴클레오타이드의 단일 ICV 볼러스(bolus)를 제공하였고, 2주 후에 희생시켰다. 8마리 마우스의 군에게 음성 대조군으로서 PBS를 제공하였다.
RNA 분석
2주 후, 마우스를 희생시키고, 프라이머 프로브 세트 RTS40595(정방향 서열 TCCTTCCCTACCTTAGTCTTGA, 본 명세서에서 서열번호 14라고 지정됨; 역방향 서열 CCCTCTTGAACCAGGAAACA, 본 명세서에서 서열번호 15라고 지정됨; 프로브 서열 AGATGGCAGCCCACATTTCTACTGT, 본 명세서에서 서열번호 16이라고 지정됨)를 사용하여 UBE3A-ATS의 RNA 발현의 측정의 실시간 PCR 분석을 위해서 피질 뇌 조직, 해마 뇌 조직 및 척수로부터 RNA를 추출하였다. 결과를 마우스 GAPDH에 정규화된, PBS 대조군에 대한 RNA의 백분율 변화(프라이머-프로브 세트 RTS108에 의해서 측정됨)로서 제공한다.
하기 표에 나타낸 바와 같이, 변형된 올리고뉴클레오타이드를 사용한 처리는 PBS 대조군에 비해서 UBE3A-ATS RNA의 용량-의존적 감소를 초래하였다.
Figure pct00207
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실시예 15: 야생형 마우스에서 인간 UBE3A-ATS와 상보성인 변형된 올리고뉴클레오타이드의 내약성 3시간 및 2주 연구
WO2017/081223에 기재된 LNA/DNA 올리고뉴클레오타이드에 밀접하게 매칭된 변형된 올리고뉴클레오타이드를 암컷 야생형 C57/B16 마우스에서 시험하여 올리고뉴클레오타이드의 내약성을 평가하였다. 상기 특정 비교 화합물 참조. 야생형 암컷 C57/Bl6 마우스 각각에게 하기 표에 열거된 변형된 올리고뉴클레오타이드 700 ㎍ 단일 ICV 용량을 제공하였다. 각각의 처리군은 4마리 마우스로 이루어졌다. 4마리 마우스의 군에게 실험을 위해서 음성 대조군으로서 PBS를 제공하였다. 주사 3시간 후 및 주사 2주 후에, 마우스를 7가지의 상이한 기준에 따라서 평가하였다. 기준은 (1) 마우스가 명랑하고, 기민하고, 반응성이었는지; (2) 마우스가 자극 없이 서 있거나, 웅크리고 있었는지; (3) 마우스가 자극 없이 임의의 움직임을 나타내었는지; (4) 마우스를 들어 올린 후 마우스가 앞쪽으로 움직였는지; (5) 마우스를 들어 올린 후 임의의 움직임을 나타내었는지; (6) 마우스가 꼬리 꼬집음에 반응하였는지; (7) 규칙적으로 호흡하였는지이다. 7가지 기준 각각에 대해서, 마우스가 그 기준을 충족하면 0의 하위 점수를 제공하고, 충족하지 않으면 1을 제공하였다(기능적 관찰 배터리 점수 또는 FOB). 모든 7개의 기준을 평가한 후, 점수를 각각의 마우스에 대해서 합하고, 각각의 처리군에서 평균내었다. 결과를 하기 표에 제공한다.
Figure pct00209
실시예 16: 래트에서 인간 UBE3A-ATS와 상보성인 변형된 올리고뉴클레오타이드의 내약성, 8주 연구
상기에 기재된 변형된 올리고뉴클레오타이드를 래트에서 시험하여 올리고뉴클레오타이드의 내약성을 평가하였다. 수컷 6 내지 8주령의 스프라그 돌리 래트의 군 각각에게 하기 표에 열거된 바와 같은 올리고뉴클레오타이드 3㎎의 척추강내(IT) 용량을 제공하였다. 각각의 처리군은 출발 체중에 대해서 대략 매칭되는 4마리 래트로 이루어졌다. 4마리 래트의 군에게 음성 대조군으로서 PBS를 제공하였다. 투여 전에 래트의 체중을 재고, 투여 8주 후에 다시 체중을 재었다. 래트는 성장으로 인해서 연구 중에 체중이 증가된다고 예상되며; 너무 적은 체중 증가는 화합물 독성의 징후이다. 체중 변화의 절대 값을 PBS-처리군에서 관찰된 체중 변화에 정규화시켜 래트에 대한 상이한 평균 출발 체중을 갖는 2개의 연구를 비교하였고, PBS 군의 체중 변화를 100%로 설정하였다. PBS-처리군과 비교한 체중 변화의 통계학적 유의성(p-값)을 엑셀의 양측 웰치 T-검정(two-tailed Welch's T-test)(2개 샘플, 불균등 분산)으로 계산하였다. 0.05 미만의 p-값은 관찰된 차이가 무작위 샘플링 오류로 인한 것일 가능성이 5% 미만임을 나타낸다.
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SEQUENCE LISTING <110> Ionis Pharmaceuticals, Inc. <120> COMPOUNDS AND METHODS FOR MODULATING UBE3A-ATS <130> BIOL0349WO <150> 62/826,521 <151> 2019-03-29 <150> 62/877,765 <151> 2019-07-23 <160> 2916 <170> PatentIn version 3.5 <210> 1 <211> 619382 <212> DNA <213> Homo sapiens <400> 1 ttatatgaat gcacatgaac ctgtcctaga aaccttccat tgacaccttc ttttaatgtc 60 atcaacacaa aacttgcaga ggagctgtca gcaggttgga aagataatct cacagagtgt 120 tgcgtaggaa tctcacaaga aatgaaatat caccaaagct tctggttaac agagaagatg 180 ataatgagga gaaaatcata agaaagatga atagtgactc agaagaggtg catctggatg 240 agagaaattt atcaatatct ttatttttct attttttgag acagagtctt gctctgtcac 300 ccaagctgga gtgcagtggc acaatctcgg tccactgcaa cttccatctc ccgggttcaa 360 gcaattcttc tgcctcagtc tcccaagtag ctgggattac aggcacacac taccacaccg 420 ggcaaatttt tgtattttta gtagagaatt tttttttttt ttttttttga gatggagtct 480 cactctgttg ctgaggctgg agtgcagtgg cacaatctcg gctcactgca agctccgcct 540 cccaggttca cgccattctc ctgcctcagc ctcctgagta gctgagggga ctacaggcac 600 ctgccaccac acctggctaa ttttttgtat ttttagtaga gatggggttt caccgtgtta 660 gccaggatgg tctcgatctc ctgacctcag gatcctcccg cctcggcctc ccaaagtgct 720 gggattacaa gtgtgagcca ccgcgccgag cagcaatacc ttttttaacg tgatttgctt 780 atatttgcat ctcattggag tgatataaaa caaatatcca catttatata tgtcgaaaag 840 agttattgtc attaattgtg aggtaaaaat tataaggtgt aggaagtatt tgtaccatat 900 cttgtcaatg attttattcc tttactatgg cgtaaaataa tgatgtattt tacaattgat 960 acaaaaaata tatttaaatt acttagaaaa cactgtcaat attagcatac tgatgttgtg 1020 attagtatag acctgatatt tatctacagg cattatgtat cattagttca ttcatttctc 1080 ccaaaatatc aaaaggtagg ttctattacc actcctaagt acaagttctg aatttgagct 1140 aaagccctgc aaaaaaaggg ctgtctccat agtccttgct cacataaact atgttagaaa 1200 atgtttttct gttaaattgt gaatacattg taggtctaat ttaataaatc ttatgctagc 1260 ctatagtcat gaagatattt tcctaacata ggttgtaaat actgtattaa aaggtattta 1320 tatttgggtc tatgatgcac ctgcaattaa ttttatgtgt aatgtgaagt taaaggtaca 1380 tttaacttcc cccaatgaac attaatttcc tagaacattg attgtaaaag ccatctttct 1440 actaataact gctcttatta attatttgca tttatattat tttgtctgtt ttgagctttc 1500 ctttatttca ttggttcacc tttctatctg tgcaaatatt acattgtctt aattactaag 1560 agtcttcatt taatacaaga attttccatc cacagccctt tagcctatct actgtggtgt 1620 tctaaaagga agaaagaggc tagtaaatcc tggatacttt gctcctacac caatattccc 1680 agctgtacct tgaaataaaa ggatttagaa ctttagaaca ttgctgttgt tgcttatgtc 1740 tctaatgttc tcttgaatct tgacaatccc cgaacactgc tccccgcttt atttgtttag 1800 tccagtccca gtgaaataaa ttagatgtca aggctcctca ttatggttgc ctggtttttg 1860 gaacctgggg tactttgtac tcctccagca acagccagag gtggcagaga gctgtcagtc 1920 atccctgggt gcctcctgcg caagcgcagt tgtcctcctg cgccgacctc gaatgcggtc 1980 ctcctgctgc agaccacgcc caccaagggc tggccgcagc cactgtagct gagctcagag 2040 ccttctgtgt ggtttgcggg ggcaaggtca gctgccccct gccctctctc tggggctatt 2100 tgaggaatgc ggcctttttg cataagaaag gcttttctct acagtaactg tggtcgctga 2160 tcaatgacac cttcctggta acatttcata ttgctttttt ggaggtgggg gtgcagatat 2220 ctttaaaact tgcatgcgat tgtctttctt ttaatcacat aaacatcatt taaaaccaat 2280 tcatattttg tattgtatat taatgccttt cattcctgta ttttaaaatg ctatcataat 2340 catttttcga aatacatatt taattatttt catctgttca atcatctttc tttagtaatt 2400 aaatgaaaat agcactttat taagaaagac aaatgttaca tattctctgt tttagtgttt 2460 tccagaaatt tgctatgaaa tacgactggt tgaaaaggag agggtcagag actttcctga 2520 gagccacagg acaaaattta cttacaatcg caggcttaaa gaagctatga tagtttaaat 2580 tacgtggctt agtttgttct tattgtggaa ggtgcacaag gaattaattt gtgtagacag 2640 aacactgaga gtcccattct gaatgcagag acagctactt tgctaccgtg caaatgagtg 2700 tcgtcatatt gtttgttttt ctccttaccc aaaagctata gacattggct tgcatatttg 2760 agtattttca ctttggtttt gtaaatggct gcttgacttg ccttcctaca gaaaatccat 2820 aatacagaga tgtattattt tcttactcct ttatgagtga ttagtttgca ctgaaataaa 2880 aatgccactc aggaaatgtc atacatcttc aagcagcata tattttaata gtatcatctt 2940 gtagaaaggg aattacaatc tttatttctt ctatatcaat gagcaaacta cttttttaat 3000 ttttatatgt tcatttttat tgacttagtc aatagtttac ctacttttta ggttttacgt 3060 gctccattaa tgtccattgt tttaggctga acctttgaca ctcctcatat atcgtttgta 3120 tgagactaga tggcaagtaa agataggatt cctcacccta ggttaaacac taacttcctc 3180 ttgaagaaac aacttaggag tccaaaaagc aggctaggaa ttgtttaggt tctgcaatac 3240 gaattgtgca aatgccaaca ggattgaatt gagagaaaca cattctctaa tgaaggactc 3300 attcctgcag ggtggatcta tgagattcaa tagcaaatgg ctgttataca agtaatgaaa 3360 tcctcaatct tatggtctaa aagcgattct ggggggcact tatttaagat acatgagatg 3420 tgaaaaagca atggaccaag agcattgata gtttatggat atttttattt cacattattg 3480 atagagcttt gtttgccagg caatgctgca gtcaggcact cggggtttca ataccctata 3540 cagaaaatct caagagcaga ccttggttaa tttttttaag taaccctcat cttcattctt 3600 ttattgtatt atgacctcgc gccattgacc ttaaatttca ctacaaattt agaagaacct 3660 aatagtcatt gcaaactaga tagataatgg tatttatgta atgaaggaca agggaaagat 3720 gattcccaaa tctgaaagaa actagaagtt ttctggggaa acaaatagag gagataagat 3780 ttactggttt attcttcatt gatgagagtt gcgttctgtt ctgataaatg gaaagctcca 3840 ttgaaattac agatggtcct caacttaagt tggggctact tcccaataaa ccatattgaa 3900 aatggtttca taaattgaaa atatcaccat aaattgaaat atcataaatt gaaaatatca 3960 ccagtcaaaa tgtgtttaac atgcctacct tactgaacat catactttag tctagcctgt 4020 cttaagagtg ctcagaacac ttatatttgc ctacatttgt acaaaatcat ctaacagaaa 4080 ccatatttta taatgtgtta aatatctcat gtaacttatt gaatactgca atgaaaatga 4140 aaagcagaat ggttgtatgg gtactcgaag tacaatttct actgaatgtg tattgctttc 4200 tcacaattat aaagttggga aatctgaagt catacctcag ggagtgcttt tattacacaa 4260 tacaggttta tcagacgcat ataccaacaa atcataggaa attcaggttt gggtcaaggg 4320 ggaggggttc aacctactta tacatatttc cttcctctct gttgggctac ctttatcctt 4380 gggattgttg caagatggcc gtgtcatgta aagggctgtg tcttttagca tcatgaataa 4440 gatgaaagag ttgaaggcca acttcattca aatgtcttct cgatgtgtcc ttcccttttt 4500 ctcctggact gctctgtgat ccatgtctct gtagaaaatg gctggcataa gtcaatttct 4560 gactgggagc tgtcatgatt actgtctccc actgttaaca ctgtacttgg aggtcttgat 4620 ggaattgggc aaacctgttc tttcagaccc tcagtttcat ctcaacacaa aactctccaa 4680 aagtccttgc tgctccacag cagggaactc tcttgaagca ataacatgag gaaatagtgg 4740 gcttgcatgg ctgcctcaca ttcctcaggt atcactgtgc tcattgcctg atgtactgtg 4800 tcttgccaac catcattcca cgtaatttac ccattcttgg tttttacatt ggttaaggca 4860 tgtacaaacc ctgttagttt ttctgcagta tttggattca taccttctga aattacttga 4920 cgattactgt gtctctggtt atttgcttct agttggcaat acaaaggaac aatgtgaatg 4980 aaactcataa agaaaaacct atgatttaat gggcgtgtgt aacactagag ggaaggtcag 5040 agttagtcta tgcatgggta taggtaggag tctcagtggg tgtcagccat tctgtgtcaa 5100 caaatcaaat atttaaggtg gatctaaaag aaaggtaata tctctgccaa ttaaactaga 5160 gtcacgcatt gactaatggc aaatacagtc taagaagtgc atttttaggc aattttgtca 5220 ttatgagaac aacgtagaga gtacttacac aaacttagat ggtatagcct actacatggc 5280 taggctatat ggtaaagcat gttgcttcta ggctacaaac ctttactgaa ctgtaagcaa 5340 tgataacacg atggtgtcat atcccatata tatacacata cacacacata catatatata 5400 catatactat agtaaaaata tgatataaaa cattttttaa ctggtactgc tgtttaaagc 5460 agatatcatg agtggatttt gcaggaccgg aagttcatcc aggtgagtga gtgagtgagt 5520 tgtgagtgaa ggtgaaggtc tagggcatta ttgtacacta ctgtagattt aagaaacact 5580 gtatgcagcc gggcgcggtg gctcacgcct gtaatcccag cactttggga ggccgaggca 5640 ggcggatcac gaggtcagga gattgagacc atcctggcta acacggtgaa acaccgtctc 5700 tactaaaaat acaaaaaagt tagtcgggtg cggtggcggg cgcctgtagt cccagcatac 5760 tcaggaggct gaggcgggag aatggggtga acctgggagg cagagcttcc agtgagctga 5820 gatcgcgcca ctgcactctg gcctgggtga aagagcgaga ctctgtctca aaaaaaaaaa 5880 aaaaaaaaag aaacactgta tgcttacgct atactaaatt tattttaaaa acctgaagta 5940 ggccaggcgc agtagctcac gtctgtaatc ccagcacttt gggaggttga ggcaggagga 6000 tcacgaggtc aggagttcga gaccagcctg accaagatgg tgaaaccctg tctctactaa 6060 aaatacaaaa attagccggg cattgtggca catgcctgta atcccagcta ctcaggaggc 6120 tgaggcagga gaatcacttg aacccaggag gcagaggtta cagtgagcca agactgcacc 6180 actgcactcc agactgggtg acaaagcgag actccatctc aaaaaaaaaa aaaaaatcct 6240 gaaatactaa tgacattatg attgctacaa tgtcacaaga taagataaat tttcaactcc 6300 attgcaatct tatgggacca gcaacgtgca tattgtctgt tgttgaccaa aacggccctt 6360 atgtggtaca tgaccctata cacataacag catattttat atttatggaa aaagcccttc 6420 tagaattata aaatcacaag ttttactcac ataaaattta acacaatatt gagattaact 6480 cataaatgaa attataaaag tcttaaaatt ttgactatga tagttctaaa caagatttta 6540 atccagagaa atgaatgtgt tcacgtaatc ctctgtggca taaagagtaa tggcaatgaa 6600 acatttctta ataaaacagg ctgcatcatt gtcagtgcga tttgcacctt cccgttgaca 6660 tccattctgt aggtattgaa tgcaggtgat cttacctgaa ggtgacaaca gaagatttta 6720 ttacaagatc acgcatgtgc cctcaataac gccatgtcat tgatgccacc agggtaacag 6780 ctattgtgat aaaatttgaa aaataaacat atgtggcttg aacccgggag gcggagcttg 6840 ctgtgagctg agatcgcgcc actgcactcc agcctgggcg acagagcgag actccgtctc 6900 gaaaaaaaca agaaagaaaa aagaaagaaa aataaacata cgctaaaaat ttagaaggat 6960 agtaagtaat aagcatttga ttgcttgagc ccaggaattg gaggctgcta tgctctgtga 7020 tcacaactat gaatatccat tgcactgcag cctgagaaat atagctaggc tccatctcta 7080 aaaaagtaaa taactaaata agtgtttgaa aatatttagc aaggaagcca tactaatgta 7140 gctgaatctt ggaaatcaag aaaaaaaatt gttcgtttaa aagggcaaaa ttaaaaaatt 7200 ctttccagat agaaagaata ggtgcagatg atagagcagc gtggcccagg ggaggggcta 7260 agcagtggac taaggatggg gaggctggag aagaggctga ggggagtcac atgttgtcct 7320 gagatgagaa agggaaaaaa agaaacatgt tcatcttcaa gtgcaaactc tcttcagatt 7380 gaaagaaagt ttttagtttc ttgggaagca gaaaagaata taggtgagga gtttgagaga 7440 ttcattaatt tctttgtgaa attcaacata aaggaagata ttctgtgttg ctctttgttc 7500 actatatgtg tggggctcac agggaagcaa tatagacaaa gtttccaaat tctcagatgt 7560 taaaggccaa tggggattca gaaaacgcaa cagaaactaa actgcaagtg gaagagctgc 7620 ccttgggagc ccagagggca agtttcaggc ctggactggg tgggcaaggg aggcctccag 7680 gaggaggagc tttggaggag attgtggaga gtgaggagca gtgagtccag caaacagggc 7740 agggaaagcg aggaggaaac agtgtgtctg tggcacaggc cagggcatga gaagagggtg 7800 gtgggttgga aggaccactg ggatgagtaa tacatgagga ggcaggagaa ggaagggcag 7860 accatgcagg gactgggcat gggggtgagg gtgccgggca gctcagaaag tgatgcaggg 7920 gccgctctct gaggactgca ttctgtgggg agggatttga atgtctcagt tcttttatga 7980 aatgttatcc ccaatccatg aggtcttctg attcaggaac cagtcagaac aggtgagggt 8040 ggccccagtc cactgtgcag gaccattagc attgccagga ggggttggtg ctgaggacaa 8100 aagagagtga aaaggggcaa agaactttct ttcctgtctg tcattttgca gatgtaagtg 8160 ggatctgtgg atctgaaaat tcacagtggc cagctcacca ccacctgatg aaagatacac 8220 cacagggtga gagcatccta acagcaaact gcaaatgagg tgggtttgca gctgcacaga 8280 gaagggaccc cagggaagct acacgggcaa ggcaggcagg ggacttcaga ggtggtagca 8340 gtgggtgttg atgaaattat tctctgagga tatacacgtt tgtcagtgta cgtgcatgac 8400 cgcttacatg ttgatgttcg catacaaacc ccacaatttt ctcatgtttt tcagagcata 8460 gcatgtattt tgactttatt ctttctacca cacgtaacca tgccttgtat acctagcaat 8520 acttaacgtt tatttttggt ggattattca tggttaatgc atttcctgac ttggtagcca 8580 aatgaaatta ccttgcttta caggcctttg gttgatcatt tctgaagatt tgtgtcgcct 8640 gaattcagtg ggggtcacct ctccatgatc ttaagcaaca gtcctgttgg gactgttatg 8700 ctatcctact taactttgga cttgtatgtc ctggaaaata tgaaactatc gatactcact 8760 tgaaaattcc aggtgcttta ccttttactt tgtttttgcc gtgtttccaa tgttatatat 8820 tttctcccac ttactttgga ttcaattgct ctgcttcctt ttacagtaaa aatttagatg 8880 tttgaatttt gggtttcaac ttttctaata tatacacact caatgctgta attttcctct 8940 aagcttccct gttgtagctg acaaattttg atgaggtgtg ttttcctttc aatttagttc 9000 aaattatttt aaaaaatttc tcttgagatt tctttgaccc atgtattatt tggaaatgaa 9060 ttatataatc tccacgtatt ttgcaattca ccagttttta aaaattgatt tctagcttaa 9120 ttctgttgtg ttttgagtgc atacattgta ttagtctgat tcttttaaat ggtttcaggt 9180 gtgttttatg gaggagaatg tggtgcatct cgatgagtgg tcctgtgggc ttgagttcaa 9240 tgtgtattct gcccgttgtt ggataaagtc tgtagatgtc aattatatcc aattgactga 9300 tgatactgtt gagttcaact atgtccttac tgattttttc tgcttggtgg atctgtctat 9360 ttctgataga ggagtgttga aagtctccaa cgataatagc ggattcatct atttcttatt 9420 gtggttttaa cagtttctgc ctcacgtaga ctgatgccct gttgctctgt tgttacatgc 9480 atatatatta aggatcatta tattttcttg gaaaatcgat ccctttatta tcacataagg 9540 tctttatccc tgataatttt cctgtattta cattacattc tttctgaagc taataaagct 9600 atgcctgctt tcttctggtt actgttagca aggtacattt tgtttcattc atttactttt 9660 atatgtactt ttactttttt tacatttact cttattaatt gacaaaattt gaggtattga 9720 ctatgtaaaa tcttcacatc atcttcaaac atgatgtttg aagaataata tatattgtga 9780 agtgaaaaat tcttgctaag aacatatgtg ttacctcaca cagttatttt tcgtggcaag 9840 aacactttac atccactctt tcttcatttt tcataatgca atttattgtt aactatagtt 9900 accatgttgt acaatctctt gatctttttc ttcctatcta actgaaattt tgtacccatt 9960 cacaatcatc tacccatcct catcccctac cacccttagg ccctagtact caccattcta 10020 ctttgtattt atataaatga gcttttttag attccgctta cacatgggtt catgtggtat 10080 ttgtctttct cttcccggca tatttcattt aacatattgt catgcagata cattcattct 10140 gcctccaatg acagtaattc tcccttttta aggccgataa tatcctgttt tgcatataca 10200 ctgcattctt tttatccatt aatctgttga tgggcactta ggttgatccc atatttggct 10260 attgtgacta attctggaat gaatgtggga gtgcagatat ctatccaaca caccggatag 10320 tcaatgaaat ctcccaaggc agattttatt acctttggat atatacccag taataagact 10380 gctcgatcaa agggtaattc tattgttttt ttttttagga tccttcacaa tttttcccat 10440 aattactata ttgtactaat ttacattccc accgacagta cacatgttcc cttttctccc 10500 tatctttatc aacactaact tttgtctttt aaaatagcca ttctaacaag tgtgagatga 10560 tatctcattg atttaaattt gcaattgtct atgtatgtct tcatatttat acagatttcc 10620 aatatacaag atataacggg gacttgtttt tagatctact ctgacaatgt gtctttaatt 10680 ggtgcatttc aaccattgct actcaaaggg attactgaca tggttgtgag aggtgaggcc 10740 agctggactt cctgggtcga gtggggactt ggggaaatct cctgtcttac agaggatttt 10800 aaaatgcact aatcagcgct ctgtaaaatg caccagtcag caggattcta aaagtagcca 10860 attgagggga ggattgaaaa aagggcactc tgataggaca gaaatggaac atgggtgggg 10920 acaataaagg aattaaagct ggtaacccca gccagcagcc acaatccgct ggggtccctt 10980 tccacgcaat ggaaggtttg tctcttcgct cttcacaata agccttgcta ccggtcactc 11040 tttgggtcca tggcatcttg gactaagagt ccaaggtcag ttcaacttgg tggagcaagc 11100 tggcagttag atgaaaaata tacacagact tgctgcagct gtacagatga tgaacgtaga 11160 actcaaaaga tgatggaggc cgggcgcggt ggctcagggc ctgtaatccc agcactttgg 11220 gaggccgagg cgggcggacc acgaggtcag gagatcgagg ccatcctggc taacacggtg 11280 aaaccccgtc tctactaaaa atacaaaaat tagccaggcg tggtggcagg cgcctgcagt 11340 cccagctact cgggaggctg aggcaggaga atggcatgaa cccgggaggc ggagcttgca 11400 gtgagccaag attgcaccac tgcattccag cctgggcgac agagcgagac tctgtctcaa 11460 aaaaaaaaaa aaaaaaaaaa aaaaagatga tggaaacaga gtagaaatga tgagaatgat 11520 gaatgatgcc tggagcttgg ttcctgggtt gctgtggtgt tagatggtca cagagcagct 11580 ttttggaagc ttatgtccat gtctcctgct aacagtagat acttgattag aatggaacag 11640 aatgtttacc tgatttttac ttatagcacc tggaatgcta gtagtaaaat gtaagccctt 11700 tggagacaga aaatttttca attctgtgtt ttcagagcct aggataattc ctctgacctc 11760 actggtgaga atacgtaggt gttaaactaa tgcacggatt aaactataag ggcaaagaaa 11820 aaagttcccc tttgtcctct gaaggttcac tgaaaaatca actggcaaaa ggaagattaa 11880 tagaagaaaa ggtatgtaaa attttatttt aaattgcata gggagggaac cacaaaagaa 11940 tgatgaccca gtgaggtaca cacgtttata tatctgtttt catagaggaa gaaggcgatg 12000 tgtaacatag actattattt taagaggcaa tagaccatca aggagaatga acagacccag 12060 gaggcaggaa gcagacatta ggagaaggtg aggtgcagag ctacgcagga agagaggttg 12120 ttgtttaatg caaattaagt cctccagata atctcttgga gctgacctca aaagaacaga 12180 cggtaggtgt gtctgggctg gtgaggactc ccagcctctt gatctttcct ggttacttga 12240 tgagatccct ggggaggatg ttcaagacca ttgcatttct ttattttatt ttattttcag 12300 atggagtctc actctgttgc ccaggctgga gtgcagtggc atgatattgg ctcactgcaa 12360 cctccaccta ccagattcaa gtgattctct tgcctcagcc tcctgagcag ctgggattac 12420 aggcgcctgc caccacaccc agctaatttt tgtattttta gtagagacgg ggtttcacca 12480 tgttggtcag gcttgtctca aactcctgac ctcgtgatcc acctgccttg gcctcccaaa 12540 gtgctgggat tacaggcgtg agccactgtg cccagcctgt aaatgcccat cccattatat 12600 ttcttttgta aagaagcttg cttggtcaga taaggaaatt tcagagaggc tcttcctgga 12660 cttgggagtg ggagacaaga ttagagagac cttcattctg aggcaaattc taagacggct 12720 cagcatgaca aagcaccagt ctttggtata tctgagcccc aacaaaataa actgatttgt 12780 gtatgaagaa tggagcttac agctcagaca gcaaatcaat ccttattgac tcagttttca 12840 acttcatctg gattaccaga tgcacagtgt gaaaataagt catttgccag cctgagcaac 12900 atagcaagag cccgtctcta taaaaagtgt aaaaatctag ctgggcatgg tagtgaccgt 12960 ctgttgtcct agctactctg cagcctgaga tgggagcatc acttgttaca gtgagctgtg 13020 atcatgatca ggtcactgca ctccaatcta gctactgagt gagaccttgt ctctctctct 13080 ccctctctct ctctctctct ctctctatat atatatatat atatatatat atagccaggc 13140 gtggtggcag tcacctgtaa tcccagctac tcaggaggct gaggcaggag aatcgcttga 13200 atctggtagg tggaggttaa agtgagctga gagtgccact gcactccagc ctgggcaaca 13260 gagcgagact ccatctgaaa aaaaaaaaag aaatgcatat aatatatata gtatatatag 13320 tatatatatc tatatataaa atagatatat atagtatata tatctatata taaaatagat 13380 atatatagta tatatatcta tatataaaaa tatagatata tagtatatat atctatatat 13440 aaaatatata gatatatata ctatatatct atatataaaa tatatagata tatatactat 13500 atataaaata tatagtatat atatgaaaat aagttatttg tattcaaagc atcaaataaa 13560 attttgtttt agttttctaa aaaaatacaa gtaacatata taggcatgct gtttttcttc 13620 ttatatgtga ctacattact ttagtatgta gcaaatatca tttgctagct gtagtaaatg 13680 tgcattgtca cattttgtcc aattttgttc aaactttaat caaatgccta agaatttaaa 13740 attaccttaa ttttgtagaa gcaaatcaca gcttatcatt ttagatgttt tacttactta 13800 tgagtctact atttcccacg ttactgctgt ttctggcctg cctgtggcag tattgccatt 13860 cactggaacc tgcttccata ggaggagcat cctgatgtgt ttaggaatac taaaattcag 13920 atcattcccc atcagagttg tctattctgt ttctccctct catccccata atgaatgcat 13980 acattctttc tgtttgtttg gtaattattg ggtcatttaa aatgaagact atgaaatgag 14040 aacagaacca ctgaccaaaa tgtacaactt tttaaacgta ccatggggaa gaaaggtcca 14100 gaacctatgc gcggagtatg ttactaatcc agagagaaag tatatttaaa aacaacctga 14160 gtggtcagga agtcaatttc ttttttcttt atttttttaa gagagacagg gtctcgcttt 14220 gttgcccagg ctggtctcga actcctaggc tcaagccatc ttccctcttc ggcctcccaa 14280 agggatcagt ttctgaagtg agatgagtga gttgattcct tgagcattgt cttaatatgc 14340 tacggctacc ataacaaagt accagagact gggtggctta cgcaacagaa gttaacgttc 14400 tggaggctat aacgttctag aggccggcaa ggttgtattc tttgtgacct ctctacgtgg 14460 ctggcagatg gccaccttct ctctgtgctc tcacctcttc cttcccctgt gcttgcacat 14520 ccctggttct ctcatccaag cattctattc ttatagggac accaggcaga taggatttgg 14580 cccaccttaa tgacctcatt taccttaatc atctaataga aggccctatg tccaaacagt 14640 cacattctga gacactgggg gtgagggctc tgcaggggag aaaaataata cctttccttc 14700 acctgctgca aggttcgtgg ctgagtcctc ataacaaaat ccagattaac aaaagaaaag 14760 tatgcaaatg catttttttt ttgagacgga gcctcacttc tgttgcccag gctggagtgc 14820 agtggtgtga tctctgctaa ccacaaactc tgcgtcccgt tttcaagcga ttctcctgcc 14880 tcagtctccc gagtagctgg gactataggc gcccaccacc acacccagct aatttgtgta 14940 ttttttagta aagatggggt ttcaccatgt tggccaggct ggtctcaaac tcctgatctc 15000 aggtgatccg ccctgctcgg cctcccagag tgctgggatt ataggcgtga tccaccacgc 15060 ccagccacaa atgcatttaa tgtaagtttt atgtgacaca ggagactacg gaaatgaaaa 15120 ctcaaacatc tagggagaac tgtgcatttt tatggacagt catttagaag tatgattgga 15180 ggacaaaagg gtatgatcta atggtaataa actgggagga acttaccaag gcctgactgt 15240 tcaggttctt cttggcctcc aagtttgata ttccttccct tcgggcatag ggcagaatac 15300 ctgtcacatg agggtcttca ggagagaaga ggtgggagca ggtcatttca aacctttctc 15360 cctctggagt tttctgtctc ctccagctta aaatccttag tgtgccaggg tgccatacat 15420 tggggtagta tttcctgtac tccagtagct tcaatgtata aatcttagcc acaacaagca 15480 tgaatagaga tttcaagcta cagaaggaag caaaggacta ccgagaggta aagatgtcca 15540 aaggtaactc tggcgaaaag aatgaactcc ttgtacagct gtgaatggga gtttgggcaa 15600 gcgttaagtc tgaacctacc tataggtggg actcttaacc attttatatt tatgcagagc 15660 gagtaaatgg aaaaatcccg tggaaaaaca ctaatcatat attgcgactt gagggggcta 15720 cagatttttt tttttttttg aggtggagtc tcactgtgta gcccaggctg gagtgcagtg 15780 gctgcgatct tggctcactg caagctccgc ctcctgggtt cacgccattc tcctgcctca 15840 gcctcccgag tagctgggac tacaggcgcc caccaccatg cctggctaat ttttttgtat 15900 ttttggtaga gacggggttt caccgtgtta gctaggatgg tctcgatctc ctgacttcgt 15960 gatccacccg cctcggccac ccaaagtgct gggattacag gcgtgagcca ccatgcccgg 16020 cttggggggc tactgattta aagaaagaaa gattaaaagg attttgatgc aataactctt 16080 taaatttttt ttttttgagt tggagtctca ctctgtcgcc caggccagaa tgcagtggta 16140 caatcttggc tcactgcaac ctccgcctcc tggttcaagg gattttccag cctcagcctt 16200 ccaagtagct gggattatag catgcaccac aatgcccagc taatttttgt atttttagta 16260 gagacagggt ttcaccatgt ttgccaggct ggtcttgaac tcctgacctc agaagatccg 16320 cctgcctcgg cctcccaaag tgctgagatt acaggcatga gccactgtgc ccggccaact 16380 ctttatttat ttattttttt ttttttgaga cggagtctcg ctctgtcgcc taggctggag 16440 tacagtggtc caatctcggc tcgctgcaag ctccacctcc ctggttcaag tgattctcca 16500 gcctcagcct cccaagtagc tgggactaca ggcacctgcc accacgccca ggtaaaattt 16560 ttgtattttt agtagagacg gggtttcacc gcgttagcca ggatggtctc aatctcctga 16620 cctcgtgatc cacccgcctc ggcctcccaa agtgctggga ttacaggcgt gagccaccat 16680 gcccggcgcc aactctttaa tttttaaaat tgggtttctg gaggtgatat ccatcctttt 16740 ccagtacaca gtttatagag tttcaacaaa tacatactgt catgaaatta ccaccgtaat 16800 caatgtttcc catagtggcc acagcttggg aaatcctaac aaaggcttta ggcttcctgg 16860 cctctgctgc catgaccctg tagaaagaat ggattacgag attcgttccc acctgcccct 16920 ccctgggtct cagatcttcc ctatctatca gataaggatt ggattgagct ggtgtagcca 16980 gtttgtctgt ccctgtgctg aggttactac ttctgctggc acccaaagca cttgttatag 17040 atctaaacaa gttgatttca gtcatccagt ccagcaaggg aggacatgtc ctatataaac 17100 ttgatgtgcc tgataacata agccacccca ctggaagtat cagatgtttc ccgcactact 17160 agagggttcc tagcaccctg gtcctccctg atcctgtccc ccaacactgt gagatcccat 17220 agaaagtggg ggtcaccttg gggaacactg ccataaaatt agagttaggg ggccctttct 17280 ggggttttat ggtggcctga accacaaacc acccccaaga acatgcactt tgaagagaaa 17340 aggaaaaaga atggtaggga acactgaggt tggaatttca caggaacagc ctaattagcc 17400 agctacctgg tccacctcca tccacatcaa gctcagtgtt tcccaacatg tgctgcagtg 17460 ccccatttcc catgcattgg agtgtagtgt ttagtgttca tactactaga tagaagtacc 17520 gcctcctgag caggccttct tgatgtccta tcttcagttg ctttggctgt tccattgttc 17580 agtagctcca ttggcttgca gatgacaggg tgcatacaaa gcccatcata ttccatgaga 17640 gcatggccat tgttttgctg gtcatgtagt gaaggatgct tcttggtgag actgaggtcc 17700 tctggggtgt tcaaaatcat gacataagtt ctcctcaata acagcaatgg tagtatcagc 17760 atccacaagc gtgcatattt tttgtccttt ccaagtagca agctgttttg atagtctttg 17820 tccccacaaa gaggctcttt aaatattcta gtcactcaat tgccattccc tgatgaggta 17880 tgtaggctgt cagcaacggc ccacacattg gtgaaatgca ggaagacctg gtggtagggg 17940 tggcctgcat ggtcatcaca aatgcgtgtt gtttggtcca ctgggcaaat tgccaaggtt 18000 tattctgaca aatgatgatg acaaccacag cctaacagac cccatctgct ctgttgtttc 18060 actgagccat cagtaaacca tgccacacca tcagcaggct tgtcttggag ccttaggctc 18120 cagacagcca tgggaggagc caaagcacac ccagtggttc tcttggtgtc ttctaattag 18180 ctagccattt gttcacggag cctgctggtc acatgtggtc ctagctgggc ctgaacttga 18240 atgcaccact tccatttgat aagtgaagtc tatggagcct gtctaatttt attggttgag 18300 cttgtgagcc atccagagag aaatggcagt tcaggttgca gagtttcatc tggcattctg 18360 gccacgaggt gcccagtcca aaacagtacc caatatcaag taaggattgc catttaaaag 18420 agggatatag gccgggcgtg gtggctcatg cctgtaatcc cagcagtttg ggaggccaag 18480 gcgggtggat cacctgaggt caggagttcg agaccagcct gaccaatgtg atgaaacccc 18540 atctctacta aaaatagaaa aattagccgg acatggtggc atgcgcctgt aatcccagct 18600 attcaggagg ctgagacagg agaattgctt gaacccggga ggcagaggtt tcaatgagcc 18660 gagattgcac cattgcactc taacctgggc aacaaaagtg aaactccatc tcaaaaaaat 18720 aaaataaaat aaagagggat atttggtggc tgcctgaggc aacttatgtg tccaagatct 18780 gagaggctgg tacaccccag tgtcagtttt ctgttgccag agacatccat cactgtgcat 18840 caggttgcac acaactgtga tttcatctgg ctagcacatt taaggtttaa aaggaagtgc 18900 ctgagacaca aattgttgta aacctgctgc tgcaaagggt tccattcaaa gtgtgtggct 18960 ttattggtta ccttgactct gggtgccaga agaaccccca tgtgagatgc atgttgtctc 19020 cagtacccaa agcgacctaa ccagctgcca ggcctccttt gtatccgtga gtgcagccag 19080 gggcttgcct gtatctggga tactgttttg gcttcttgct caggtagctt tggcattcat 19140 tgtgcccatg gcctttttga ccagctaaac tgggctgtta cattgtgaca ggtgggttgt 19200 cacttttttc tttttttcga gacggagtct tgctctgtca cccaggctga cctggtgcga 19260 tcttggctct ctctaacctc cgcctcccag gtttaagcac ttctcctgcc tcagcctcct 19320 gagtagctgg gattataggc gcccaccacc atgccctgct aatttttata ttttagtaga 19380 gacggggttt caccatgttg gccaggctgg gcttaaactc ctgacctcgt gattcaccca 19440 cttcagcctc ccaaagtgct gggattacag gcatgagccc ccacggccag ccggttgtca 19500 catttttatc tgtaacaagt aaatccagaa ttaataaaat agtgtcattg ttccatttag 19560 tatgcagtac cacttttttt aatgattcag tgcggcttgg gtagcttagg taacaggcag 19620 gagtggatac ggcccactat tgtgtcttag ttcttagctg tgagggggca taatcttcca 19680 ggacatcaat gcctataatg cactcagggt gggaaccaga gccacctgca taaaaagttg 19740 ctcacagggc tctacccaca agtacataag cattgtgtgc agataagcat cacgggccac 19800 cagtttgttc ccaaacctcc caatgtcatc cgtttaatta ttctcctaaa aggacccaga 19860 aacattgtca tgtgggttcc ggtatccaag cacctgagaa aaaactgaag tcttctcttt 19920 tctcctctta tcataacaag ggtataaggc cagagggctt cagtagggac ctagaggcct 19980 tggccccatt cttaactgtg tcaatcagac caagacactt aggtggcagt gttcctttat 20040 caaacactca caatagccac actgcgtaag atttccctgg tcttcctcct tatcctttcg 20100 agcctgactc ttcccatctt ctgggctgac attgtacgtg ttagttcctc tcatgcctca 20160 gggaccatac aaggacctct ctctagtttc ttcttgggtg cctcaggggc tgtctgaata 20220 ctcaccattc aagctcttgg gccctgacaa taagggatca cataagtgcc cagcacctag 20280 gggaccttga actatgatct gctgtttcca cattcctttc tctctgtctc agtccatgca 20340 gccagctcac ttacatctgt ggggaggaga gtgacatgtc ccatttacca cccatcctta 20400 tccataactc atccaggtac atgtccagcc cctgtgctcc tgggctgatg tctctgcctt 20460 gggctgagta ctgggtggta ttgcccctcc cactttgcca gaaagccatg tttctctgac 20520 cgaaccttac ccactgcacc aatttttcaa agcaggttca ccaattacca atcccaaggg 20580 aggactccac cacacagagg acagcaaagg tcatcactat accagccatc aggaatagga 20640 gtccagacac ttctacccac tgcatcctcc gctgcagtgc tacaactgcc tgagagcagt 20700 gagacagaac acattctcag gcagtaagtt aaaggatgca catttattat ttacagatag 20760 ggagaaagtc ttccttcaaa agaagcctag gctccattct gagctcatcc ccaaaggctc 20820 aagaagggtt cccagggcag atgaagtctg gattgcaaat gccccccttt cacacagctg 20880 aggaagccca aaaggcagcc caccctgggt tacatatctc agggcagaca tggcgcattg 20940 agcaaagctt taaggaaata ctgctttcag ggcagagagg aacaaacccc agctctcctg 21000 gacagtccct ccctaactaa agatgtgaca ttccttagga agggccagaa caaggccagg 21060 gttgttccag acagtccctc cctagctcag aatattgcat tccaggctga tgctacactt 21120 attcttgaca aattaaaact gagaaaatgg gaataattga atccatccaa ggccacctgg 21180 aggactgttt tgcattttca ccccaaaagt tccttgtagt agtcttccca ccatatttag 21240 ttttggaaat tattgatatc tatctccata actttgcctt ttacagaatg tcatataaat 21300 gaaatcattc tgtatgtaat ctttcagtaa cactttcgag atatgtcatg tttactgtat 21360 caatggtttg tttctttttg aaactgacct gtgctatatt caatgaatgt accacaattt 21420 actcaattgt ttatgttttt ttttaagaca gagtttcgct cctgttgccc aggttggagt 21480 gcaatcctgc aacctcggct cactgcaacc tccacctcct gggctcaatg attctcctgc 21540 ctcagcctct ggagtactca tcatttttat taatataaaa tgttataaat atggataact 21600 tgatggatat ttgtgttgag gtattatatg gttactacaa gcatatggtt tcattcatct 21660 tgggaaaata gatcttagcg ctgagatgct ggatcatata acaaaagtat gattcagaag 21720 gctggttgtg gtggctcatg cctataatcc caacactttg ggaggccaag atgggaggat 21780 cacttgaggc caacagttca agagcagctt cgccaacata gtgaaacccc atctctacta 21840 aaaatacaaa acttggccgg gtgcagtggc tcatgcctgt aatcccagca ctttgggagg 21900 ctgaggcagg cggatcacct gagatcagga gttcaagacc agcctggcca acatggtgaa 21960 accccgtctc tactaaaaat acaaaagaaa attctccagg tgtggtggtg catgcctata 22020 atcccagcta ctcaggaagc tgagacagga gagtcacttg aacccacgag gcagaggttg 22080 cagtgagccg agatcatacc actgcactcc agcctggatg acagagtgag actccatcac 22140 aaacacacac acacacacac acacacacac agaaaactta gctaggcgtg gtggcacacg 22200 cctgtaatcc cagctcctca tgtggctagg gcatgagaat agcttgaacc tgggaggcag 22260 aggttgcagt gagctgagat ggtgccactg cactccagcc tgggcgatag agctgactct 22320 gtcttgaaaa aaaaaaaaaa cgtatgattc actttacaag aaactgccaa aatgttttcc 22380 aaagtggcta tcattttgca tcctaacaga aaatatggga atccccgtta ctccacatcc 22440 ttaccagcac ttggtttgga ctctgtgtgt ttgtgtgtgt ctgtagtgtg tgtgtgtgtg 22500 tgtgtttgtg tgtgcgcatg agtaaatata tgtgtatata tgtatatata tcgactctta 22560 ataattccag tagggacata gtggcacctt actgtggttt caataattta catcttcctg 22620 ctgataatgg cattgaataa aactcattaa cttgttcgtc atccatatct actatttgac 22680 tgtcactctt ctcatttcaa aaaatgttta ttgttgtatt attaaattta actatgtata 22740 tgtataattt tgatatgacc tacatctgtt aagtaccgaa aatatttttt tctgagcctg 22800 tgccatctcg tctttctctt aacagtgtct gtcaaagagc agcatttatt ttaattttga 22860 ctaagaataa tttgtccttt tttgttgttt ttttttgaga cagagtctgt ctctgtcacc 22920 caggctggag tgcaatggca cagtcttggc tcactgcaac ttccgcctcc tgggttgaag 22980 cgactctcct gcctcagcct cttgagtagc tgggattaca ggcaccctct atcatgcccg 23040 gctaattttt gtacttttgt agagatgggg tttcaccatg ttggccaggc tggtcttgaa 23100 ctcctgacct caggtgatcc acctgcctca gcttctcaaa gtgctgggat tacaggcatg 23160 agccactgtg cccagccaat ttatccattt ttaaattttg tgcttaatat ttattcccta 23220 ccattatata ttgcttaaca caaggtcata aagattacct acagtatttt ccttagaaat 23280 tttatgtgtt aaggatttac atttatatct gtggtatttt gaattaattt tatatctagt 23340 gcaaaaaagg gtgaagagtt ttgttttgta ttttggcata tgaatgctct gttgttttag 23400 gagcttttgc tacaaatact ctcctttctt caattcaaga aaattgaatt tccgtggcac 23460 atgagtcaaa aacctaccaa ccatatatgt atatgctata atgctccagt tatctaaata 23520 tttatcctta tacatatcca tatatgaata tgcatatgct atacatacat acatatatgt 23580 atttgctata ctgttccatt tatctattta tccttacacc aataccacac tatcttgact 23640 aataccacat tatattaaac ttgaaataat ggccaggtgc ggtggctcac gcctgtaatc 23700 tggcactttg ggaggccaag gcaggcagat cacctgaggt cgggagttcg agaccagcct 23760 gaccaacatg gggaaacccc atctctacta aaaatacaaa aattagccga gtgtggtggc 23820 acatgcctgt aatcccagct actcgggagt ctgaggcagg agaatccctt gaacctggca 23880 gacggaagtt gcagtgagcc gagatcatgc agttgcactc cagcctgggc gacaagagca 23940 aaactccgtc tcaaaaaaaa agaaaagaaa agaaaacgtg aaataagtag tgagtccccc 24000 aatattgtcc cttttcttct aaattggttt ggctatacta attatttagt ttcttacata 24060 aattttggaa tctacttctc agtttctaaa aaaaatataa aaaatcagct gaggattcta 24120 ctgaatgtat agataaatat gtaagaattg acccttggtc aggcgtggtg gctcaagact 24180 gtaatcccag cactttggga ggctgaggtg ggtggatcac gacgtcagga gcttgagacc 24240 agcctgacca aggcatggtg aaaccctgtc tctactaaaa atacaaaaat tagccgagcg 24300 tggtggcaag cgcctgtaat cccagctact caggaggcta aggcaggaga atctcttgaa 24360 cttgggaagt ggaggttgca gtaagccaag atcgtgccac tgcactccag ctggggtgac 24420 agaacgagac tccgtctcaa aaaaaaaaaa aattgatcct taatattgag ctttccaatc 24480 cattaaattg gtatatcttt atatttattt agattttttt gaatatcaat ctgatcagca 24540 ttttctaatt cccagagcac acattttgca cacattttgt caggtttatc tcgaagtata 24600 tcacgttttt atgctattat aaaatacatt ttaacttcta tagtcaattt ttcattatca 24660 gtataaagga agtcaaccga ttttcactca ctcattttta caaactaagc aaatctagtg 24720 gcagccatgt ggtatataca ttgctacttg tgagggatgg ataaatgaaa aacatttctc 24780 ctttatttga ggcatttgtc aagcagagat atgaacaaat aggcaatgca aatcagaggg 24840 gttgtagtag ggaatgtgca ttattctgtg gaaatccaca aaatgcatgg gcatacaaac 24900 caaatttaaa tagtcataga aggaatcctg caggaagtaa tttatgattg aataaagtag 24960 ctgaaaacca tgcaaattag aattagacaa gacaaaagaa ggattagtat tcaggtagag 25020 accagggtgt gtctacaagt caacattttt gagacatcac agggagagta acaatttcag 25080 tacactgaag gaagttagaa atctatgtca gggctagatt tttaagaaat tttgttctgt 25140 gtcaataagt taggattttt atagttttct aaggttctat tcagctacta tggggtcgac 25200 tcaagaatac agctgttgta attgttaaaa tgggaatttg ggagtctttt gaatttgaaa 25260 gaaaaaacaa atgtgcggga ttgaggctca gaccctgtac aggcaaagaa aaagttaaaa 25320 gtgaggaaaa tgagagacaa cataaactct gggaaaagtg ttcacaaaaa attttagtat 25380 tttcagggta gaagctcctc ttgattgagt cataccttcc tgcgaaagat acaaagtcag 25440 aaaagaaatc ctctacctag aaaacgacat tttggcacca agcataggtt actttcatgc 25500 cttaatttca ccttaccagc atttcaaaat acctgctaca ctgtggtttg aggaatgaga 25560 ctactatgct cacagcgcca cctagcatca acagaaaggg aggcccatgg caaacttaat 25620 aacaagaggc gggaaaaaaa aggtgaggcc caggaaccgg aaacttaatt tgagcaggat 25680 ttttcttata tttatttaaa aactaaaata ttggccgggc actgtggctc atgcctgtaa 25740 tcccaacaca ctgggaggcc gaggcgggca gatcacttga ggccaggagt tcaagaccag 25800 cctgggtaac acggtgaaac cctgtctcta ctaaaaatac aaaaattagt gggcatggtg 25860 gcgggtgcct gtaatcccaa ctactgggag gctgaggcag gagaattgct tgaacctagg 25920 aggtggaggt tgtagtgagc cgagatcgcg ccactgcact ccagcctggg tgatagagtg 25980 agactctccc tcaaaataat aaaataatat tgctgcaggg gtcagtggtg aaatgcaatc 26040 cataaccatt cccagtaaac actcagcgag tcctggccca tgcccacttt tcctgtcatt 26100 taacgcaagg gttaaatatc aaagtgaatc ccattatgct aattgattta caaatacgga 26160 tgtataggag tgtgataccc tgagcgcaat catacttcgg atataactgt aaaacgactt 26220 cagctgactt tgcagtgttg cagtgtcaca ttaaacccta agttgtttgt gtttccctac 26280 acatcactct ccaggagcat tatagttcag aagattagag taatttctta gactaaagcc 26340 ttgatgggtt attattacat aaaacgtttt ccactctgat ggagaagtca ggtgcattcg 26400 ctcatgtctc cgtggcaggg ccgggactcc tggtcccccg cgattctgag cggtgcctca 26460 cagcctaggt cctccaacct cacagggcgg cccgcagcaa atgcgccact gtccggtgcg 26520 gccaaccagc tcgtggtgcg ctgtgggaag gtcacaggac ggagctgggg ggcgggggcg 26580 gcggtggggg cgggggcggc ggcgggggcg ggggcggggg cgggggcaga tcctatttgc 26640 gcctgcgcgg gactggagga ttcggtgttg ccctttcccc ctgctatttc cgtttccgcg 26700 cttcaagcgg atctcttccg gttatggcgc ccgctgggag tgtcttatca gccgcttata 26760 ccgcggaaac tttaacctgc gttttcccgt aaaattttcc tctctaggtt tcgtatcatt 26820 gtcttgtttc ttactcttgt attaactttg ttttaaccta aggtttctct ttcccaaaaa 26880 ctgtggtgtt tctttacaac ctctttttat agttatataa acattgcaag aaccatgatt 26940 ttatattctt ccttttcagt attaataact tcaatgtctt ttttggcatt tgtctgaaaa 27000 tttgaaatat ttttcaattt actgaactga ttatcgtttt gtaaatatcg gatactactt 27060 taatcatttg tgtattggcc ttaagattct ctatttttaa ctcttccacc aacatacctt 27120 taatctgaga ggtgttgtag gggcttcaag atcaaacttt ccccacagtc tctattttca 27180 ttataaaata ccgtgtttta agaaaaaatg tacaaggttg aaagaagttt cactactacg 27240 tgtttttttt ttaattttta ttttatttta ttttattttg agacggagtc tcgctctgtc 27300 accaggctgg agtgcagtgg tgcggtctcg gctcactgca acccccgact ccctggttca 27360 ggcagttctg ccgccgactc cctggttcaa gcaattctgc ctcaacctcc cgggtagctg 27420 ggattaccgg cacatgccac cacgcccagc taatttttgt atttttagta gagatggggt 27480 ttcaccatgt tggccaggat ggtcttgatt tcctgacttc gtgatccacc cgcctcagcc 27540 tcccaaagtg ctgggattac aggcgtgagc caccgcgctc ggcctctact atgttttaaa 27600 acagtggcta ggtcatgctt ttctgtgtat ccttacttcc cttattccat cacctcatcc 27660 atcactttac aactgatcat acaattacaa aattatttta ctaatcagat taaatgtgtg 27720 ccttccattt gaagaagaaa ggtctactaa aggcttagtt ttccctagga cactgggaga 27780 atacaggatc tggtttccag tgccacagtg gtgatcacac aggaataaac gggacacagg 27840 tcagacaaca gccagaaagt catctgccag tatatgtttc ctgtgagatg gacacctggt 27900 cccaggtcag acacaggtgt tagagtgtca gctaggtaaa agaagtaacc tgaaagagac 27960 acgctgtgaa caactatgtc cacctcccct tcatttccta gtattggagg gctgctagct 28020 gctctgttac taggacccag atttagttgg ggcctctcag aacaggtcag aattgaccta 28080 tgcacagtac ctgtgggagt ctggatgagg gccatccact gaaagttagt gaatcaaaga 28140 tttaagattg atctaaatgc aaatagatct gtgtcaaacg actatacgca taattgcctt 28200 attttatact tattgaaaaa atcctcgtaa aattataaag gcataagatt tacttgttat 28260 gaaaatgaag gcaataatga acgtaattca taagtgaatt tgcaaatatc ttgaaattcc 28320 aattctgatt tttccaaatt agattttgat tcagagtcat cgatgtcttc acaccaccct 28380 ctgtggcatg aacagagatg gtaatgaagc atttcttaga aaacaaggct ggaccactgt 28440 ctgtgtgatt tccacctttc ttgctgacac cattctgcat gttttgatgt aagtgatgtt 28500 accagaagga aacagcagaa ggttgcaaaa caagtgcaaa caatgaaagc catgtcatgg 28560 ctgccaacag gctaatagtg attgtaacaa cacttgacaa aataattttt aaaaattatt 28620 caaatatgat aactaataac gatacagaat tatcaaggga ggtccaattt ttttttttgt 28680 ctgagacgga gtctctcttt gttgtccagg ctggagtgca gtggcacgat ctcggctctc 28740 tgcaacctcc ctgacccagg ttcaagcatt tctcctgcct cagcctcctg agtagctggg 28800 attacaggcg gctgccacca cacccagcta atttttgcat ttttagtaga gacggggttt 28860 caccatgttt tttggccagg ctggtctcaa actcttgacc tcaggtgatc cacccgcctt 28920 ggcctcccaa tgtactggaa ttacaggcgt gagccactgc acccggccta agggagctct 28980 attaatggag ctgaatctat gaaacaagaa catcttcctt catcaaggga gcaaaactgt 29040 ccagaaaaaa agtacagatg aggtagaagg agcctggtct atgtgttcat ctttgtggtg 29100 gattgagaat agggaggctg gagaagaggc tgagggggaa gtcagggctc actcctgtcc 29160 taaaagcaaa agggagcaaa agaaccatgt tcatcttcag attcacacat tcttcacttt 29220 gaaagaaaat ttaagtttat taggaaacca tatctgtgag gagtttttat tttttttttg 29280 ttttcttttt ttgaaacagg gtcttatttt gttgcccagg ctggagtgca gtggcatata 29340 cactgttcac tgcagcctct acctcctggg ccctagcagt tatcctacct cagcctccca 29400 tgtagctggg accacaggca tatgccacca agccctgcct attttatttt tttgtaaaga 29460 cgtgtctcac tttgttgccc aggctggtgg ggggaagttt tagagattca ttaaataatt 29520 tgtgaaattt aaaataaagg aaaatattct gttttgggtt ttgcccagtg catgtttggg 29580 gctcataggt gaacaacatg gacaaaataa cctctgatat ttcagtccag tagtgattca 29640 aggactgtaa cccaaatctc aaatgtagga gttttgggtt acaaaacttt tgggagctga 29700 gagcacaggc atcagacctg aaatggaatg gacaaggaag gcctctagga ggaggaacat 29760 tggaggaggt tctggagagc gtggagcagt gaatctggca aacaggagaa agagaagagg 29820 aaaaaatgtg tctgtggcac aggccagggc atgagaaggg gacagtggat tagaaggact 29880 gctgggatta gcaacatgta aggagggcag gagcgggaag ggcagaccat ggagaggctg 29940 tgaaggggag agtgggcagg tcaggaagtg acacagggcc ggccagccca ctaaggaatg 30000 catttgttgt gctggtagtt caaatatcag tctcgttcct tgcaacagta cctccaggtc 30060 aagaagagtg aggatagcct ctgtgtctga ggaggtccct gtgcattatg aggaattggt 30120 tctaggaaga agggagagtg aagaggaaca gagaggaccc tccagatcca gtacgggcca 30180 actaagggaa cttggatgct cctgttcatg tccctttctc catcactgag actcgcccca 30240 tcccaccctg aatgcaggtt cctttcccct cggttatttt gtgcgtctca gatgatgaca 30300 tgtattgtaa ctttattcta tcacatatga cttttacatt atatcataga aaaagttact 30360 tacataaatt acttaatggt ggattagtca tagttaaaat gttgtcagct tggtaaacaa 30420 atgaaattat cacactttag tttttcttcg ttgatcattt atgaagatta gtgtctcctc 30480 atttcatgga tgtcacaact acatgttctt aagtaaggtg tatgcttggg gtgttgtgtt 30540 ttccctgtta atgttggata ctccagtgtt cagcaaacta taaacctatc aacacacatt 30600 tgaaaaatcc agttgttttg tgttttattt cgtgtatcct gtctttacaa tattatatct 30660 tttcttctgc ttacttgaaa tttaatttgc tcttcttttt ctaggttcct aagatggaaa 30720 cttaggcgat cattgggcat catcataggg tctacctgcc aaatcaggtc ttcttcattc 30780 tgcaaaagtt tctcagtcac cacttatatt tcatgacttt gacccttgtg aaaataccag 30840 tcagatatct tgtggaatgt cccacaatgt gtatttgtct gatggtttct cataattaga 30900 ctagaaacaa tgtgtaaatt aaacatattt ttccaaatta gaaaacaaga aaaacagaat 30960 aacatattag ttagaagtat taacataggg ctggacgcag tggcttatgc ctataatccc 31020 aacactttgg gaggtgaagg tgggcagatt aattgaatcc agcaattcag caattcaaga 31080 ccaatctggg caacatggca gaacgctgtt tctaaaaaaa atgcaaaaaa ttagctaggt 31140 gttgcagcat atgtctgcag tctcagctac tcgggaggct gaggtgggag gattgggagg 31200 gtggcctgag cttgggaggt caaggttcac tgagctgtga ttgtgccata gcgctccaac 31260 ctgggcaaga gagtgagacc atatctcaac aaaaaagaga gaaaagaaaa aataacagag 31320 aaaaataatt tttaaaaatc aggtaatgac aaatagggaa ttccaaatat attgctaatg 31380 gtctgttaag cttgacagtg cttttagaaa acttgttctg tttagaatag tgttagactc 31440 acagaacaaa ttggtaatat aaagagttta catataccac acacagtttt ccttattata 31500 aatcttaaca ttagtgtgtt acgcttgtta caattaagaa ccaatgttaa acattatcat 31560 tcactgctat ccatgcttta ttcacatgtc cttaatttca cttaatgtcc attttttgat 31620 tctggaatcc catccaggat gacacatcat atttagatgt cattcctctt tatgcttcat 31680 aagctgttga cacttccttc aactttcctg gtctttcatg acattgacat acttcattag 31740 gaagttgtct gatttttttt ttttttgaga tgactctcgt tctgttgccc aggctggagt 31800 gcagtgacgc gatctcggct tgctgcaagc tccgcctccc aggttcacgc cattctcctg 31860 cctcagtctc ccaagtagct gggactacag gcgcccgcca ccacgcccag ctaatttttc 31920 gtatttttag tggagacggg gtttcaccgt gttagccagg ctggtctcaa tctcctgacc 31980 tcgtgatctg cccacctcgg cctcccaaag tgctgggatt acaggcgtga gccaccgtgc 32040 ccagccatag gttttcaaaa ggaggactac acagggaaat tgccattctt atcacatcat 32100 accaatgtta catactaata gcatgtcata tcatgttgac cttaatttga ttacctattt 32160 gaattacttc ttatcagatt cttccactgt taaattgcta tttgttacac ttcctgtgtt 32220 gtacttttga aaagaagtca ttaggcttag taagaagtgg gaagtcattc ttcacctctt 32280 tatgggaaga gtatctgcaa aaataatttg gaatccttca acatgtgaaa tgtgtcagtt 32340 ttcctccatt tgttttatat attttttcac tcatttattt atatcaatat gcaaacatgg 32400 atctttattt tacacttaca ttttactagt ttattttgtt gttcaaaatt ttctactctt 32460 ggctattgga aggtctttta attggctact atatcatttt cgtatacaca ctcctagtat 32520 aatggcatga atccgtttat gaggctaaag ccctcaaggc ctaattacct tttaacagcc 32580 ccacctttta atactgctac agtggcagtt agtttccact aactgtaggg gacaaaaatt 32640 caaaccatag caagaacata ccaaaaccat ttttaaaaac aataatgcat ttatttctgc 32700 aaaaaatggc cataaagggc cacctttata tgtgatcatg tagatcaccc tctatatgat 32760 aaggaagaca aatggagaac gaattagata gagaactgtt gtgaattaaa gtattaggtt 32820 tggaatacaa ctttttgggt tgattgctca tatttcttag aacagaaatt ctcagtgtac 32880 aactttaact ctgaagaaag ctacccatcc aatgaagaag tagcaaagtg actgtttgcc 32940 atttctatct tccttctcaa tagatttatt gaaacatagc atatacatca cctctccaca 33000 tttgttgtac ttttgttatt tctagttcat tcttgaggtt tctctttaac acagcgacta 33060 ttaattctag cccagttggc caggagctgt ggctcacacc tgtaatccca gcacttgagg 33120 ttgaggtggg tggaatgctt gagctcagga gttcaagacc tttgggcaac atggtgaaac 33180 cccatctcta ctaaaaacac aaatttagct gggtgtggtg atgggcacct gcagtcccat 33240 caccatactc gggaggctga ggcaggagaa tcacttgaac ttgggaagca gaggttgcag 33300 cgagccgaga ttgtgccact gcactccagc ctgggtgaca gagcgagact ccgtctcaaa 33360 aaaaaaaaaa aaattctagt gctgctcaag aagcctctag aagatttgtt catggatgtt 33420 tacattgtgc ctttcagggt acactttttt aaatcttatt ttacagccaa atacataatt 33480 atctgatttg tcagtggttt tattctccat tgtgaaatgt aaagtaatga tgcaacctat 33540 aattgatgtg aataatttat tttgcaatta ctatttatgt cagtatcagc aaatactaca 33600 ttcatttgta tagatgatat taatctacag gttttatgga ttattagttc atttcatcct 33660 cacagcatct caagaggtcg gcactagttt tactcccaat cacctagtga atttgatcta 33720 aagccctaca agaaaggaat ggatgaaact tgattttgac tgagtctatc tttgaagtct 33780 ttacttacat cacgtgtttt agaatatctt tttttgtatg gaaaacacat tctaggaccg 33840 gattaagaaa tgttactcta gggccaggcg cagtggctca tgcctgtaat accagcattt 33900 tgggaggttg aggcaggcag atcacgtgag gtcagaagtt tgagaccagc ctggccaatg 33960 tggcaaaata ccgtctctac taaaaataca aaaaaattat ccaggcatgc tggcgggcac 34020 ctgtaatccc agctactcag gaagctgagg caggagaatt gcttgaactc aggaggagga 34080 ggttgcagtg agccaagatt gcaccattgc actccagcct gggcaacaga gcgagaatct 34140 gtctcaaaaa aaaaaaaaaa aaaaaaaagg tattctaccc cggaagtcat gttcccaaat 34200 tagatgtaaa tcctgtgtta aattgattta atatttaggt ctaagatcca cctaggaatg 34260 attttatgtg taatgtgagg ttatagatca gattttattt ttccctgtgg atatatttct 34320 tgaaatattt atagaaaaat tcacatttcc ccaattaatc ttataaatta tttgtgtata 34380 tatgcttgtg tctgatttgc tctctccttt ttttttccat tggtttattt ctctgtgaaa 34440 atatcacact attttagtaa gacacttcat ttaacacaga attttctctc tagggccttc 34500 tcttagccaa gtgtgctatt atataaagaa gaaagagtga aaacctctat gccttgaacc 34560 tacaccaata ttctcagttg tcccttgaat aaagagcaga atttagaact cactattact 34620 gatgacactt aggtctttaa tgttcttgtg aatcttagac aacccccaca acatcattcc 34680 ctgctttatt tgcttagtcc attcttggtg gattttatga gatgtcaaca ctcctcatta 34740 ggattccctc cttctgaagc ctttgggatt ttctacccac ccagcaacca ccagaggtgg 34800 cagaaacccc tgcagacatc cttcttgcgc aagcgcagtt gtaccatgaa tgcggtcgtc 34860 ctgctgcaga ccacgcccac caagggcggg gccacatcca ctgcagctga gctcagagcc 34920 ttctgtgggg tctgcagtgg caaggccagc cgccccctgt cttccctctg gagctgtttg 34980 aggaatgcag ttcttttgca taagaaaggc ttttctctcc agtcattctg cttgctgatc 35040 aagaacactt aacagcttca ggctttcctg gtaatattca ttcttgcttt tgtgtttttg 35100 ttttaaggtc caaatatctt taatacttgt atgcagtttt cttttttata atttcacata 35160 aacatcatct aaaaccaact tcgcatgttc gcattctgta ttaacaactt tcgtttttgt 35220 atttaaaaat acattcataa tcactttttc aaaatatctt gtcagttatt ttcatctttt 35280 ccatgatcat tctttaccag tgcaatggaa atattacttt tattaggaaa agcagatgtc 35340 acgcggtttt tagtgttgtc gagaaatttc ctatgaaaca tctctggttg aaaaggagag 35400 gaacaaaatt ttatgtgagg cacaagatca catatgctca gaatcgcatg ctttaataaa 35460 ggctgtgatt atttgcatta tattgtttag cttgttctaa ttgtaaaagg tagacaaaga 35520 attaatttgt gtagacagaa cattgcgact cccattctaa atgtagagac agtcactgca 35580 ctgcgcaaat aggaatgtcg tcatgttgtt tgcttttctc cttaccccaa aactgtagac 35640 attggctaga gtctttgatt tttttcccaa cttgcttttg taattgtcgg catgatgttt 35700 gcacagataa ccaatgatat agatatatat ttttttctta ctatttgatg aatgattaat 35760 attttgggtt ttttttatgt tttcagtgaa tcaaaaatat cattcagaaa atgttgtcat 35820 ccatatccag gtagcatata gttttataat ctgatcttgt aataaggaaa ttacagtcct 35880 tattgatttt ctgttattag ttagcatttt ttaagttttc atgcttgtga gtatttggga 35940 attttttttt tactctgtca ataatttaac acctttgtat tggtcatctg ggtcgatgtc 36000 tattgtttag gctcaacctt tgacactcct ctgaggtagt ttttatgtga atttgtaacc 36060 acccaaggga ttcaccttgc cagctgtcta gacagagccg atttatcaag acaagggaac 36120 tataatagag aagcaagaat tcacccagag ccggctgtgc aggagaccat agttttatta 36180 ttactcaaat caatctccct gtagggggat caggggtttc taagaataat ttggtgggta 36240 gggggtcgga aagtggggag tgctgattgg tcatgttgga gatgaaatca tagggagtgg 36300 aagctgtcct cttgcgctga gtcagttccc cggttggggc cataagatca gatgagtcag 36360 tttattgatc tgggtggtat cagctgatcc atcgggagca gggcctgcaa tagatctcaa 36420 gcactgactg agcttaggtt tcacaatagt gatgttatcc ccaggagcag tttgaggcag 36480 tttagagtcc tgcagtctcc agctggatga atcctaaacc gtaattttta atcttgtagc 36540 tgatttgtta ttcctacaaa ggcatgatgg aggggggttg ttttgggaaa gggctgttac 36600 tgtcttcatt taaaagctaa actataaacc gaattcctcc tgaagttcgc ggggaatgaa 36660 caagggcagc ttggaggtta gaagcaagat ggagtcagtt aggtcagatc tctttcactg 36720 taataatttt ctcagttatg attttttgca aagatggttt caaattgatg gcttagtgtc 36780 ctgggtagtg aaaatggaat tcctcaacct gaattgaaca tggatttcct cctgaagaaa 36840 caatttaggg ctccaaaaag taaaccagga gcctggcaca gtggtcacac ctgtaatccc 36900 agcactttgg gaggctaagg cgggtggatc ataaggccag gagtttgata ctagcctgga 36960 caacatggtg aaaccctgtc tacttaaaaa aaaaaaatac aaaaattagc cgggcatgct 37020 gatatgcacc tgtaatccca gctactcggg aggctgaggc aggagaattg cttgaacttg 37080 ggaggctgag gttgcagtga gtcaacatcg agccactgca ctccagtctg ggtgacagag 37140 aaagactctg tggggtatga tgaggcttct cttcaaatag cctgatcaat cgtttattct 37200 ttaattaata gtaaccccca cccccttttc ctttttctct tttttctttc tgcctttgtt 37260 gcatgcccgg acatgccaca gtagcaggct tatcagtacc agctcacatt cctttcctta 37320 tttggaaagg agactagctc tctagctcat tgcagacacc ccttcccctt ttcccctctc 37380 tcccttatgt gcccacctta tctaaagaaa gttcaattgt ctagccaacc aggattagtt 37440 cagactgtgc gacctgacct ccaccaatgg gaaaagggta caggggcagg acttggggca 37500 ggaataaaga ctcttgtgcc cctttgttct ggtgtgcttt catggcgact ggccaaggag 37560 aagcacccct ctgcgcagaa gtaaaattgc tttgctaaga atcctttgtt tgagtgttca 37620 atctccctta ggattttgag cattattccc aaccattcaa tccaaaaaaa aaagtagacc 37680 aggattgatt tagggcctgt attataaatt gtacaaatgc caacaagatt gtattccact 37740 agaggaacgc attctctagt gaaggaagca ttcctgcagg atgagtccct gagactcact 37800 agcaaatttc atacaagtaa tgaaatcctc agtctaatgg aataaaaaca attccagggg 37860 catttgttaa agatgtataa gatgtgagaa accaacagac taacagcatt gatactttat 37920 ggatattttt attccaaatt aatagatgtg ttacaggaaa agggtcctga tccagacccc 37980 aagagagggt tgccgatatt cagggccagt ctgcagagta aagtgaaagc aagcttacta 38040 agaaagtaaa gcagaaaaag aatggttact ccatagacag agcagccctg tgggctgctg 38100 gattcccatt ttcatggtta tttattgatt atatgctaaa ccaagggtgg attatccatg 38160 cctccccttt ttagaccata taaagtaact ttctgatgtt gccatggcat ttgtaaactg 38220 tcgtggtgct ggagggatgt agcactgagg acgaccagag gtcactctcg tcaccatcat 38280 ggttttggtg gattttagcc ggcctcttta ctgcagcctg ttttatcagc aagatcttta 38340 tgacctgtat cttgtgccag tctcctgatg tgacttaaaa tgccttaacc atctgggaat 38400 gcagcccagt aggtctcatc ctcattttac ccagccctat tcaagatgga gttgctctgg 38460 ttcacatgcc tctgacagat ggacatttgt ttgccaagca atgctgcaat caggggctct 38520 ggatttcagt cctccataca gagaatgtca agggcagacc ttaataaaaa taaataaatg 38580 aataatcaaa tttttaaaat tacctctttc attcttttat tgtattatga tctgacacca 38640 ttaactttaa ttttcttgca tatggagagc aacttgatac aaactggtat ttatttagtg 38700 aagaaaagag ataaggtgat tcccaaattt aaaggaaact ggaagttttg tgggaaacaa 38760 atggaggaga taagacttac tagtttctac ttattttaat gagaattgtg ttgttcattt 38820 ataaatacaa agctccattt aaattacaga tgcttttgat ttatgatgag gttacttcca 38880 gataaaccca tcacaagtta aaaatgtcat cagtcgaaaa tgcattgaat atacctaact 38940 tagttaaaat cacagcctag cctatcatcc ttaagtgtgc tcaaaacact tatattagcc 39000 taacgtttgg gaagatcatc cacacaaagc ctattttatc ataaagtgtt gaatatctca 39060 tgcaatttat tgaatactgt actgaaacag aaaaacagaa agattggaca ctcaaagtat 39120 agtttccatt aatgtgtatt gcttttattt aatttaaaaa ttttaagttg aatcatagca 39180 agtgaggaag cccatatatt ataaaatgta ataagtttac cagccacaaa taacaacaaa 39240 tcataggaaa tgcagggatt gggttgaggt gaggtggttc aacctattat acccatttcc 39300 ttcatctcta atgggctgcc cttcatcctt ggggttgttg cagggtggct gtgcagtgca 39360 aagggcacac aagaattgct tgaacctggg aggtggaggt tgcattgagc tgagattgtg 39420 ccactgcact ctagcctggg caacagagtg agaccccatc tcaaaagcat aaataaataa 39480 aaggataata tctctgtcaa agtacagtga tgcattgctt aatcatggaa ataccttctg 39540 agaaatgcat tgtttggtga tttcatctct gtgcaaacat ggagagcatt acacaaacct 39600 agaaggcata gcctactaca catccaggct acatggtact tactattgct cccaagctat 39660 aagcctataa gcatgtgact gtcctgaata ctataagcaa ttgtaacaca atgataagta 39720 tttaaacatg taacctatct aaacatagaa aacataaaaa gatggtataa aacaaaaaat 39780 attgttcagt tgtatagggc agttgccatg cctggagctt gcaggactgg aagttcttct 39840 gggtgagtca gtgagtgagt ggtgagtgaa tgtgaagacc taggacatta ctgtatgcta 39900 ctgcagactt tagaaacact gtaaactaag gctacactta atttattaaa aactaaagta 39960 attgtgctat ggcatcgtga cagctttgac atctctaggt gataggaagt tctcaggtca 40020 attataacct tatgagagta ccctcctata tgttgtcttt ccttgacaga ataaaatatc 40080 attttgagag ccatgactaa taaacacata agagtcgatt taatatttat tttaaaagcc 40140 cttccatagt tataaaagca taagttttag tcacatcaaa atataaacaa tcttgaaatt 40200 aattcataag taaatcaata gatatcttga aattgtgctt atgatagttc taaaccagac 40260 tttaatgcag aatcttggat atcttaatcg cactgtgtgg caggaagact gatggcaata 40320 aaacatttct taaaaaagag gctgcagcat tttctgtgca atttgcacca ttcctgttca 40380 cacctgttct gtaagtgttg ctgcaggcga tcctgtaaga aatgacagcg ggttgcagcg 40440 caagttcatg caaacaatga aaagcatgtc atggctacca ctaggctaac gctattgtaa 40500 taaaatttga aataaaatag actagaaatg atgaaatatg agaacaacat tggaaatatt 40560 tatcaaggga accatattaa tgtaagcgaa ttttagagaa caaaatactt ttcctaggtc 40620 tgcaaggaca aaactgtcca gaagaacaga agagggacag atgaggtaga agcagcatgg 40680 cccatgagag gggctctgca gtggattgag ggtggggagg ctggcaaaaa ggctgggcag 40740 aatcagggct cacatcctga cctgagaaca gaagagagca caagaaacag gttcatcttc 40800 aggcacaaat cctcttcaga ttgaaagaga gatggagtgt ctagggaagt aggcaagcat 40860 ttggggaagg agagtcactg attcattagt gaaacacaac aaaaaaacaa aatcttctgt 40920 gttgctgttt gtccactgca tgtgtggggc tcacagggga acaacataga caaagtttcc 40980 aaattctcag gtgtttaaga cgagtgagga ttcagaaaac ttaacagaaa ctaaactgca 41040 agtgcaagag ctgcccttag gaactcaggg gacaggcatc aggcctggga tgggatggac 41100 aaggggggcc ttcaggagga ggagcattgg aggagatgct gaagagtgag gggcagggga 41160 tccaccagac aggggaggta aagggaagag gaaacagtgt gtctggcaca gttcagggca 41220 tgagataagg gcagtgggtt ggaaggatcg ctgggatgaa taatatatga ggaggcagga 41280 gcaggaagga cagaccataa agggcctgag caggggaggg aggacagctc tggaagtgat 41340 gcagaggctg ctccctgcgg actgccttct gtggggagga gttcgaatgc cttttcttct 41400 tttaagtgtt actcacaatc catgagatct actgacaagg aagacagttg gaacaagtaa 41460 gaatagtcct tgtttgatgg gaaggagcag tagcattacc aggaggggtt ggtgttgggg 41520 aggggcaagg gtggggaagg gcagagaagt ttctgtcccc tcagccattt tgcagatgta 41580 ggttggatca ctggatcaca aattcacagt ggctggctca tggccacctt gcatcacagg 41640 gtgagagcag cctcacagga aactgcagat aaggggggtt cccagctgca cagaagaagg 41700 acagcaggta actttcagtc aaggttggca gggggctgca gaggtggcag caatgatggt 41760 ggtgggcagt gtgcagcctt gtaggccact gtctccatgg acatacagat ttgcacgcat 41820 ctgtgtctgc gtgtcctctc ggtgtgctga cattcttaca aaatcctcat gaatttctca 41880 ttgttctgag accataacat gtattttgac ttttttctac cacatgtacc ctttcatgtg 41940 tacctagcaa aattgaccaa aattccttat tggtggatta ttcatagcta cagtattttc 42000 caacttaata actaaatgaa ttgccctgct ttgtatatgt ttgcctaatc attcctgaag 42060 attcatgtct cctcatttca gggggagcca cccctgcatg ttcataagca ggagttcagt 42120 ttagggtgtt ctgttttcct agttaactgt ggacacatct gcgttctgga aactattaaa 42180 ctctcaatac tcatttgaaa attccagtta ctttatcttt tacttagctt tcactttatt 42240 tacagtactc tctcttttct cctgcttact ttggatttcg tttgctctac ttttaagttt 42300 cctatggagg aaatttagat tatcgatttt tagatgtttt ttctttttta aattttattt 42360 atttatttat ttttatttta ttattatttt tttttttgga gagggagtct ctctctgtcg 42420 cccaggctgg agtgccatgg cgtgaactct gcttactgca agctccgcct cccgggttca 42480 cactattctc ctgcctcagc ctcccaagta gctgggacta caggcgccca ccacaacgcc 42540 cggctaattt tttttgtatt tttagtagag acggggtttc accatgttag ccaggatggt 42600 ctcgatctcc tgaccttgtg atccgcccgc ctcggcctcc caaagtgcta ggattacagg 42660 caagaaccgc cgctcccggc ccctcttctt ttcttttttt tttttttttt ttttttggtg 42720 gaattttgct tttgtcacac aggctagaat acaatggcgc aatctcggct cgctgcaacc 42780 tctgcctccc gggttcaagc gattctcctg ccttagcctc cctagtagct gggattacag 42840 gcgcccgcca ccacgcccag ctaatttttg tatttttagt agaaacgggg tttcgccatg 42900 ttggtcaggc tggtctccaa ctcctgacct caggtaatct gcccacctca gcctcccaaa 42960 gttctgggat tacaggtgtg agccactgtg cctggccaat gttttttttt gtttgtttgc 43020 tttgttttta atagatacat ttccccccta tgctccctca ctgcattcta caaattttga 43080 taagatgcat tttaatttaa acttagttca aaatgttgtt taattttctc ttgagatttc 43140 ttgcatcatg tgttatttaa aagtgtgtta gttaatctcc atgtattttg aagtttacca 43200 gttatgtgcc ttttattgat ttctatctta attttattgg ggttttaggg tatatatttg 43260 ttaacataaa aatcatgaga tctataaatt tggaaagaaa aagagctata aatattcttg 43320 aaggtagccc tacagcatgt atactgaaca aacatgcacg taacctatga cccatgttca 43380 ccttggtgtg gagactgagc tttttttttt ttttttttga gacagagtct tactctgtcc 43440 cccaggctgg agtgccatgg taccatcgtg gctcactgca acctctgcct cccaggttca 43500 agcgattcac ctgcctcagc ctcccaaata actgggatta cgggcacctg ccaccatgtc 43560 cagctaattt ttgtattttt agtagagaca gggtttcacc atgttggcca ggctggtctt 43620 gaactcctga cctcaggtaa tccacccgcc ttggcctccc aaagtgctat gattacaggt 43680 gtgagccacc acgcccagct gagacttaac atttaaatgt attacagtta ggccctacac 43740 acaaaagccc ctttcaggac acaaaggcag acaagtacac aatctctaga aaccagtcag 43800 acccagtcca tgtttggtgg gctcttatca ggagaaagtt actgaaatca gtctcttgtg 43860 caatcaaggc tgtagcgatg gctgttggaa cagaggctgg agttagcgtc tggcggtgga 43920 tgagctgcaa attgttttaa gattgtttat gtggaagtca gtgcttgctt agctgctaga 43980 gaaaaagata aacctcctgt cagttagaac atagtttatt cttcaactat aggggtgagt 44040 gacttaaccc ttgcctgtca tggccttagg tcttatttat aatttgatat cttattgcca 44100 ccaagaagag ttcattcctt cattcttatg atctctattt taatatgaat gctggtcagt 44160 tgttgtgtct aaactgcaaa agagacagat gataacgagg catgtcccac ttcctgtccc 44220 atcatgactg gaaactcagt ttgtatggtt tccctgcggt cctgtctgtt cagtcagttg 44280 gggggcttag gattttattt ttaattctca tagaggagtg ttgaagtcac cgaccgtaat 44340 agtggattca tctatttttc ctgttttaac ggtttctgcc tcgtagtttt atgttctgtt 44400 gctacatgtt agaattatta tatcttcttg gaaaattgac cccactatta ttatgtaatg 44460 cctttctatt tccctgataa tttttctgac tgtatagtca gctttttctg aaattaatat 44520 agctactcct gctttttcta tttgcttgct atattttgtt ccatctattt actttcagtt 44580 aatatgtctc catttttatt aaataacaga taaaatgaga tgtatgtact atgtataaca 44640 tgaggtttga ataataatgt gcattgtgga atggctaaat ccagctaatt aacatgtgta 44700 ttacctcaca tagttatcat ttttgtggag agaacacttt ctatccactt tttaagcatt 44760 tttttaaata gacacaggct ctcgctctgc acctaggctg gagtgcagtg gtttgatcac 44820 agctcactgc agtgtagacc tcctgagctc aagcaatcct cctgcctcag cttcctgagt 44880 agctgggact acaggtgcac accaccatgc ccagctaatc tttagcgttt taaaaataag 44940 acttatgttt ttaactagag aaaccatatg gtacaataga tctcttgaaa ttattcctcc 45000 tctctgactg aaattttgta tccatccaca aaacttctgc ccaaccccac cctcaacccc 45060 aggctctggt aactaccgtt ctacatcccc acttgtatga aatcacattt tttagatttc 45120 acatgagtaa gatcttgagg tatttatctt tgtatgctta acatttcagt taacataatg 45180 tactccaggt tcaaccatgt tgtcgcaaat gacaggattt cctttttata tgcctcagta 45240 gtattccatt ggggattata tatataattt tctttatctg tcaacggaca cataggttga 45300 ttccgtatgt ttgctattgt gaacaatgtt aaacacttct cattgaggag tgttgaagtc 45360 accaactata atagtggatt catctatttt tcctgtttta acaatttctg cctcatagtg 45420 gtttgaacac tgctaaaata tacatgagtg taggtatctc ttcaacatac tgatttcatt 45480 ttctttggat atatagccag cgttgggatt gctagatctt atggtagttc tatttttaat 45540 tttttgaggg gcctctatac ttttttcgat aatggctgta ccgattaaca ttctcatcaa 45600 cagtgtgcag gggtttcctt tacaacacct gttatcttta ctctttttaa taatagcctt 45660 gtaacaggta taatatctca ttttgatttt aatttacatt tccctgtatc tgtctttata 45720 tttaaataag tttttttttt ttggggggga cggagtctca ctctgtcgcc caggctggag 45780 tgcagtggtg tgatctcggc tcactgcaag ctccgcctcc ctggttcacg ccattctcct 45840 gcctcagcct cccgagtagc tgggactaca ggcgcccgcc accacgctca gctaattttt 45900 tgtattttta gtagagacag ggtttcacca tgttagccag gatggtcccg atctcctgac 45960 ctcatgatcc acccgcctcg gcctcccaaa gtgctgggat tacaggcgtg agccactgcg 46020 cccggcctta aataagtttt ctctagagaa catatggtta agtcttgttt tttgatccac 46080 tccaacagtc tgtgtctttt cattggtggt tttgagccat tgaaagtcaa tgtgattatt 46140 gataatagca gattgctatc taccatgttt atttctgctt ttcatttgct gcccttgttc 46200 tttgttcctc ctcctgtctt ccatttgttt gcttcccttt atggttttaa ttgagaattt 46260 catatgatcc aattttctct tcttagcata tcattatatt ttctttttat ttttaaatat 46320 tttagtagtt gccatatgaa ataaaaactt tttcatattt tagttgatat aacagataac 46380 agtttgttaa aaacaaaaat tgtagccatt tatttgatga ggtattctta tgtttatagt 46440 ttgagtgtgt gtgcatgtat atgggtgtgt gtgtgtatat atatatatat acacacacac 46500 atatacatat gcatgaatgc tcatatataa atgcaatgaa tgacagcaat agtacaaatt 46560 accaaagtac aaatgactat tgtttcctta ttataggcaa ctcacactac ttgtgaactg 46620 atagagtgtt atttgaaagg gagtttgaat taactgtaaa tttagggact ggctattgga 46680 ttaagatcct ccattccttg gctggctgtt gtccagaggc tgcattcagc tccttcccat 46740 gttggcttct cccacatggc agaatgctcc atcaaagcta caaggggaga gtttgctagc 46800 aagacagaag taatgatttt acatagcata attacccatg tgatgtacct tcagctgtgc 46860 tctattctct tgtttcaaaa taagtcaagg ttgctgccca cacttacagg gagaggatta 46920 gaatgcaagg ttgtgttcac cagcaggtgg gaatcactgg gtgccaatct agggtctgct 46980 tgctgtgtca gatcttctcc aacctgcaac agtttctcag tgttcaatta ttttgtataa 47040 cctgaattct tttgaaaagt accagtcagg tgttttgtgg aatttcctac aaaatggatt 47100 agtctcatgg gtctcattat tacaatagag atatgcatta atttagacac atgtatgtgg 47160 gtgttaagaa aaactgaaca atgtattact tagaaataca aaaggagaga ccaggtgcaa 47220 tagctcacac cggtaatccc agcactttgg gaggacgagg tgggaggatc acttgaggcc 47280 aggagttcca gactagccta ggcaacatag ccagacccta tctctaacca caacaacaaa 47340 aatttaaaat tagccaggca tggtggtgca cacctgtggt ccaagctact agggaggctg 47400 aggcagcagg atgtcttgag cccgggaggt cgaggctaaa gtgagccatg atcacaccac 47460 agcgctccag cctgagctac agagtgatac cgtgtctcaa aaaaaatggg gatatgcact 47520 caggggtttt caacaatatt gacaaggttt ggcttattat actgggaagg gaatttataa 47580 aaaagaaact tgttaaattt tagaatagtt tagatataca cagcagttgc caagataata 47640 cagatcattt ccttatgctt agcatatagt ttcccttatt attaatccct tacattagtg 47700 ggtgatattt gtcacaattc ataattcagt agtatacatt atccttctct atgattcaca 47760 ttttatttag aatttttctt ctaccgaatg aacactttgt gttccaggat tccctccagg 47820 agaccacatc acatttagaa atcccatctc attaggttcc ttctgcctgt gacagtttct 47880 cagactttcc ttgttattga tgacattaac atccccaatt tgggatttct ctgacatttt 47940 tctcatgatt atactggagt tgggtttggg gaaggaagat cactgagaga aaatgtcatt 48000 gtaaccacat catatcacgg gtgtctacta tcaacatgat tcatgcctgt tgatagcaat 48060 ttgattacct ggacaagtta gcctttgtca aatttcttta ctgtaaaatt atttctttct 48120 ccactttccc tgtttcactt tttgaaaata agtcagcata catagcacat acttaagaac 48180 aagaaagtta tgctctacct ccttatgaac tgaggaccta aaacaagagt tgagaactct 48240 ttactgtata cagttggcct gttctccacc atgatttcat accatttatt tatactgtat 48300 tgaatatgat atgaaattag atatattcag ttcacatctc ccttatactc ctttatttca 48360 tagctcgaat tgttccattg ttggccattg gaaggtctct cagttggctc ccatatcatt 48420 ttgaaatagc cacattattt tggttagatt ttgcttgttt ggtggttcaa ttgtaatgtt 48480 tcatagtttc ttactttcag gcactacagg gtcctccagg ccaattgtgt ttatttcgtg 48540 cccaagcctg gtacccatca tttcttcaag ggtcctagtt tcttttattg gaaaatggct 48600 tttaaaacaa agatacagac ccaggtatat tcactgatac tgggtcatct gtcgatttga 48660 ggagtagtca gctgacaaaa caatgaaacg tacctgtgta tactaaccca cacatataca 48720 catatgtgta aatatttcct catatgttca tatataacct gattaactta aacataaatt 48780 cctactaatg tctccagcac tacatgaata taatataact tgaatcaatc tccccattcc 48840 cactacttgg ttgtaacccc cactctaaca gtgagtgagt tggccttgtt aacttaatca 48900 ccaagttaga ggctacatgc atagtggctt cagaattgtt catccacact ctcatgaaga 48960 acaacattac caactaaagt acagtgctca tagacaactt cttggacctt tagatgcaga 49020 atcttcactt tgtacccaag ttacttaggt cagttctttc ccccgcctcc cagcttcctt 49080 tagtgaggtt atatcataca tttcttattc atttttctta ttttctctgt attcctctat 49140 gggatccctc aacctacaaa taattatttt ctctgtattc ctctatggga tccctcaacc 49200 tacaaataat tttttttttt tggttttttg tttgtttgtt tctttgtttt ttgagataga 49260 gtctcactct gtcacccagc ctggagtgca atggtgtgtt cttggctcac tgcagcctcc 49320 gcctcccagg ttccagcaat tatcttgctt cagcttccca ggtagctgag attacaggca 49380 cgcaccacca cgcccggcta attatttggt atttttagca gagatggggt ttcactatgt 49440 tggccaagct ggtctcaaat acctgacctc aggtaatcca cccacctcgg tctcccaagt 49500 ctcccaagtg ctaggattac aggcgtgagc caccatgcct ggcttacaaa taatattttt 49560 aatttccgta catttaggtt cactgtttgt attataaagt tatgcagggt ttcaaaaaca 49620 atatgatgta gcgaccatgc aggaagtttt tattacccta aagaaattcc atctacttca 49680 cctatttcac tgtcctcctt ggagagtccc tagttagcat taatctgttt actatctcta 49740 ttattttacc tttcccaggg tgtcatatac atggaattgc acagtctgtc atcttttcaa 49800 actggcttcc ttaacttaaa aatatgcctt taattttatg aagtatatct tacggtgatt 49860 tagatttgca ttgctgaagg actaatgatg tcaatcatct ttttatgtgc cctttgggga 49920 tacatattct ttgaagaaat gtctatttat acaatttacc catttttagt tggtatttgt 49980 cttttatttt ttgagatgtg acaatctttt atatattctg aacagtagac cctcattacc 50040 tatatgacta gcaaatattt tgtctctttt ttttttgaga caaagtctcg ctctgttgcc 50100 caggctagag tgcagtggtg caatcttggc tcactgcaag ctccgcctcc ccggttcaca 50160 ccattctcct gcctcagcct cccaagcagc tgggactaca ggcgcccacc accacgcctg 50220 gctaattttt ttgtactttt agcagagacg gggtttcacc atgttagcca ggatggtctc 50280 gatctcctga cttcatgatt cgcccacctc agcctcccaa agtgctagga ttacaggcgt 50340 aagccaccac gcccggcctt ttgtcctctt tttagggttg ttttatactt cttgatagta 50400 tatgttgaat gacaaacatt ttaaaaaata gatgaattta tctatttttg cttctgttac 50460 ttgtgttttt tgtgttatat cttagaaacc attaatttca gaccatgaag atacattttt 50520 aaaataactt tttttttgag acatgagtat cacttttgtt gcccaggttg gagtgcagtg 50580 gcacaatctc agctcactgc aacctctgcc tcctgggttc aagtgattct cctgcctcag 50640 cctcccaaga ggctaggatt acaggtgcct gccaccacac taggctaatt ttgtattttt 50700 agtagagaca gggtttcacc attttggcca ggctggtctc aaactcctga cctcagatga 50760 tccacccacc taccataccc agtcaaaaat acattttttt ttggaaaata tagtttaggc 50820 tgggcgcagt ggctcacgcc tgtaatccca gcactgtggg aggccaaggc gggcggatca 50880 cctgaggttg ggagttcgag accagcctga ccaacatgga gaaaccccgt ctctactaac 50940 aataaaaaaa ttagctgagt gtgatgaaac atgcctgtaa tcccacctac ttggcaggct 51000 gagacagcag aatcgcttga acctgggaag cagaggttgt ggtgagctga gatcccacca 51060 ttacactcca gcctgggcaa taagagtgaa actccgtctc gaaaaaaaaa aaaaaaaaaa 51120 aagctgggtg cggtggctta cgcctgtaat cccagcactt tgtgaggctg aggcgggcgg 51180 atcacactgc actccagcct gggtgacaga gcgagactcc gtctcaaaaa aaaaaaaaaa 51240 aaaaaaaaaa tagttttcct cattgaattg ccttggcaac ttttgcaatc catagaccat 51300 aaatgtcagg gttaatcttt ggacagtcac ttatattcca ttgacctata tcactgtcct 51360 tatgccagta ccacaatgtc ctcattacta tcactttata ttgtttagaa atcccataat 51420 ccaactttgt tctgcttctc attaccagtg tggttctttt agatctcatg aatttccata 51480 tgaattttag aatcagctta ccaattactc ccgccttgcc cgcaaaaaaa aagcaacagg 51540 gattcccata gcacaacgac atcactctgc tggacagcaa gagggtgtgt tcaggaacca 51600 tacctagtct acaaagccat gggactacat accacagtcc cagggacaac cacaaaatca 51660 agactcttct tttgtttttg tttctttttt ttttttttga aacggagtat tgctcagtca 51720 cccaggctgg agtgcaatgg cacgatcccg actcactgca acctctgcct cctgggttca 51780 agcaattctc ctgcaaatat tttgtctctc tttttttttg agacaaagtc tcgctctgtt 51840 gcccaggcta gagtgcagtg gtgcaatctt ggctcactgc aagctccgcc tccccggttc 51900 acaccattct cctgcctcag cctcccaagc agctgggacc acaagtgccc accaccacgc 51960 ctgcctaatt ttttgtattt ttagtagaga cggggtttca ccgtgttagc caggatggtc 52020 tcgatctcct gacctcgtga tccacctgcc tcggcctctc aaagtgctgg gattacagac 52080 gtgagccacc gtgcctggcc aactcttctt tttatggtct gaaatcacgg agtatattct 52140 ctacatctca ttcctacctt caatgaggaa attagttcct gggatctgat gacctggagt 52200 gagagatgca gctgatctag accacatttc tcacttctga gatcagaata gcaaatatgt 52260 atgtactagt aatttggaca tttgcaattc aagaaacctc gcacctccca cagcatactt 52320 cattcactcc atgagaaaaa aacaaactca cttaaatatt catcttcaga aaaaaaaaaa 52380 aaaggctgcc cgctgcggtg gctcacgcct gtaatccact ttgggaggcc aaggctggca 52440 gatcacgagg tcaggaaatc gagattatcc tggctaacac agtgaaacct cgtctctact 52500 aaaaatacaa aaaattagcc gggcgtggtg gcaggcgcct gtagtcccag ctacttggga 52560 ggctgaggca ggagaatggc atgaacccgg gaggtggagc ttgcagtgag ccaagatcgc 52620 accactgcac tccagcctgg gtgacagagt gagactctgt ctcaaaaaaa aaaaaaaaaa 52680 aaaaaaaggc agagtggcag accaaaaacg agccatatgt caatctggag taggagtgac 52740 caatgtcaga gtggaaaatg agggctgatg agctttggtt ctcaggcttt agagtaaagg 52800 tggtagatgc aaaactgtct atccaccgtg ggtttatact gataagtggg cagtaaatga 52860 aagaatagtg taatcagctg atgttagagt gcacctttta acaacgttca agtacagatg 52920 catcttaaaa ttgacattgt aaaaacaaag tttgccagaa tctagtcata atatggctgt 52980 ccttgtctgc acatgcatga acttgatctg aaaacctttg attgacgtct tctggtgata 53040 tgatcaccat caaaacttac agagatgctg tcagtaggtt gaataatctc ataaatagga 53100 gagtaggact ctgtcaagaa atgtgatgtc accaaagttc ctgattagca aagatgatga 53160 caatgtgggg taaatcatgg acagggtgtg ttgaaggtga ttcagaagag tttgatctga 53220 gtgacaggaa ttttaggaat gctgttgtta gtgtattctg cttatatttt ccatctttgt 53280 catcatagaa gtgatataag actaatacct gcatttatag tagttgaaag tttttttcag 53340 taataatata aaattgtaag tgataagatg tatttgtcct atagtctacg aatttattcc 53400 tatattgtga cataaaataa tgatgcattt tacaattgac tcaaataata actatttcaa 53460 ttccttagaa aacactgtat gagaaaatgc tgacttcatg tttagtatag atgtgctatt 53520 agtctacagg ttttaagtat tattagttca ttcaattctc acaacatttc aagaggtagg 53580 caatattacc actcccaagt tccagttgtg aatctgagct aaagccttac aggaaaagag 53640 tagaaaaacc tgagcttgac tttgtctgtc tccagaatct ttgtttacat caactatgtt 53700 agaatatctt ttctatgata aatacatcct aagtctagtt tcagaaattg tgctttacac 53760 aatagtcatg aaattatttt tctcaatttc aatctaaatg ctacattaaa tcgtttttaa 53820 gttcaggtca atgaaccatc tggtgatcat tttgtatgta atgtgaggtc aaaggtgaga 53880 tttttattcc ctcccccacc gcaacagaag aatattcaat ttcctagaac attgatagaa 53940 aaatcaattt tccccccatt gaactttaat atgtatgtat aagagttttc cactgggcat 54000 ggtagctcac acctgtaatc ccagcaattt aagtggctgt ggtgtgagga ctgcttgagc 54060 ccaggagttt gagaaaggcc taggcaacat agcaaaacac tgtctctaca gaaataaaaa 54120 ttttaggccg ggtgcggtag ttcatgcctg taatcccagc actttgggag gctgaggcgg 54180 gcagatcacc tgaggtcagg tgttcgagac cagcctggcc aacatagtga aaccccatct 54240 ctaccaaaaa tacaaaaact agccagacat ggtggcacat gcctgcagtc ctagctactc 54300 gggaggctga ggcaggagaa tcgcttgaac ctggcaagtg gaggttgcag tgagccgaga 54360 ctgtgccact gcactccagc ttgggcagca gagtgatact ttgtctcaaa aaaaaaagaa 54420 aaaaaacaaa aaaaataaaa attttaaaaa taaggagtgt tcaacactct ttctacttgc 54480 taacacttat gcaggttcaa atcttgcctt ttaatatttg tttttaattt gtcttgcaga 54540 ctaatgtctt tatcacttgt gtacattttt tttcctttgg ccacataagt atcatctaca 54600 acccaaaata catttctcct ttatttaaag cacaagtcaa gcagacgttc aacaaatagg 54660 caataaaaat cagattaaag atactgtagg tccaggagct gtggctcatg cctttaatct 54720 caacactttg ggaagctgag atggtggatc acctgaggtc aggagtttga gaccagcctg 54780 gccaacatgg tgaaacgtct tctctgctaa aaatacaaaa attagctgag tgtggtggcg 54840 tgcgcctgta atccaagcta ctcaggaggc cgaggcagga gaatcgcttg agcccaggag 54900 gcagaggttg cagtgagctg agattgctcc actgcgctcc agcctgggcc acagagcgag 54960 actccatctc aaaaaaaaaa aaaaaaaaga tgctgtagta ggaaatgtgc attactctgt 55020 tgaaatccac aaaatgcatg agcatacaac ccaaatttaa gtggtaattg aaggtttcct 55080 cgaagaggca gtttgtgatt gaatagatga agaataagca gctgaaaacc atgtaaatta 55140 gaactaataa ataacaaagg atgattagta ttgaggtaga gaatgggaat gtatagaatg 55200 caaaaaaaat tgagacatcg caaggagagc agcaatttca gtacacttga aggaagctag 55260 aaatatatac cagggctaga tttttaagat atttaatgcc gtgtcaatgt gttggtattt 55320 tataattttc tgtagttcca gacattagct agggtgtgct cacttaggaa cacagctgtt 55380 gaaattgtaa aatgagaatt tgggtctcat acatttgaag aaaaaaatat atggggttta 55440 ggttcagatt ctgtacagac aaaggaaaag tatgggtggg gaaaatgtga gacagcctga 55500 ggtccaggaa aaatggccac agaaaatttt cgtattttca gataaaatct actcttcaag 55560 ttagacctcc ctacgaaaga tgctagttca ataatgaatt ctccacctgg aaaaggacat 55620 ttcagctcca agtccaggtt gctttcatgc cttaaagtca ccttatttgt atttcagaag 55680 cacgtgctac actagcttta gggaatgaag aaccatgtgc tgacagtgcc atctagcatc 55740 aacagaaaca ggaaccaatg gcaacctaaa taagtacaga aaaaaaggtg gggtccagga 55800 accaagaatg actgctgatt tgagcaggat ttttacaatt tgttttaaaa cttaaacata 55860 atgcatagat gctgtggaat taaaaaatgc aacctaggcc gggcgcggtg gctgacgcct 55920 gtaatcccag cactttggga ggccaaggcc ggcggatcac ctgaggtcag gagttcaaga 55980 ccagcctggc caatatggtg aaacatctct acaaaacaca cacacacaca cacacacaca 56040 cacacacaca aacacactag ccgggcgcag tggcgcgcgc ctgtaatccc agctactcgg 56100 gaggttgggg caggagaatc gcttgaaccc gggaggagga tgttgtggta agccaagatc 56160 gggccactgc ctggcgacag agcgaaactc cgtctaaaaa agaaaaaaaa tgcaatctaa 56220 taatgtccag caacgataca gggaagcctg gcccatgctc acttttccag tcacctgctc 56280 ttaagtagtg cacgggttaa agaacgatgt gagtgctagt ggctgattct ttcacttaca 56340 aacatgcatg tacacgattg tgttaccatg gacaaacaca taaaatttga ttgtaaaact 56400 agttgactct taactgtgac acattaaatc cttgagtaaa tgagtgtgtg tttccataca 56460 tatattcagt accactacag ttcacaaaat gaacgggact tcttaggtta aagccttgtt 56520 aagttattct ttaaaacgct ttccaatctg atagagagct ctggcgtatt cgctcaagtt 56580 tccgtggcgg gtctagggct cctgaagccc cacgggtctc actgctaccc acatggctat 56640 taccgcaacc accgctgcca cgcagcccgc aagaaatgtg ccaccgttct gagcggccga 56700 caaacccgca gtgcgctacg ggaaggtcac ctgacagttg gggagaacgg cagcccgcag 56760 gggccgatct tcggcgcgcc tgcacagcgc aggcggaatt ggggcgcctt ttctccttcc 56820 ggtttccgtt tccgtgcgcc ccgagggtct gttccgctta tggcgcccgc cgggagtctc 56880 cctttcttcg caagcgttaa cctgcgtttt actcgtaaaa atttgctttc taggcttcgt 56940 ataattgttc tggtcttgca ctttatgtgt gcattagcct tgagtttgct tgttgttttc 57000 ccatgaaaaa ttgtattgta tttctgtaac agcccctcct cttgttacat aaacattgac 57060 cagtaattgt atatccttcc ctctcaatat taacaatttt atcttttttg cgttctttga 57120 aaaaaacgaa atccttttca aaaatactga acttgtcatt tttaagaaat gagatactac 57180 tttaatcatt tctgtattgt ccttaagatt ctttatatat tctttattgt ttatcttttc 57240 cactaatata cctttaatat gagaggactt gtagaggctt cagggtcaca ctttcgaaac 57300 ccagagtttt agtatctcct tatagaatat ttgtaattta agaaaaatta tacaaggttg 57360 aattttcaaa aatatatttt taaaatatat ttaaaaaagt atttttaaat atagtcctcc 57420 ggaatgcaaa aggacaatac tactttcagc tagtactttt taagtgatta ttttccgcca 57480 cgtattcttt tgaaattatg catttaggcc gggtgcggtg gctcacgcct gtaatcctag 57540 cactttgggc ggccgaggca ggcagattgc ctgagctcgg gggttcgaga ccagcctggg 57600 caacacggtg aaacctcgtc tctactaaaa tacaaaagaa attacccggg ggtggtggtg 57660 ttcgcctgta gtcctagcta ctcgggaggc tgaggcagga gaattgcttg aacctgggag 57720 gcggtggttg cagtgagccg agatcccgcc actgcactct agcctggagg acagagtgcg 57780 attctgtctc tacaaaaaaa aaagaaagaa agaaattata catttaattg aagctcagaa 57840 aatatatgtg tgatgttttc tatgaaatga aacattgttt agatgagaaa ataaatgtaa 57900 aatgcatttg ccttttcaaa gcagcaatta gtggcgaagt gtgaatacaa aaccagtctt 57960 ctttctgcag agaccatgtc tgtcaccctt gtgctggaat gaacaacatc acatattttt 58020 ttgtttgcat atggcctgag ggtcaaattc tgcccagcat gtttgctttc ttttttaaat 58080 aaatatttat tggaacacag ctatgctgtt catttttgta ttgccgatag ctgccttaat 58140 gctacaatgg cagtagttgc aagagacaga atgacccata aaaccaaaat tatatactct 58200 ctagccttcc tatcacccac tgttctgtct ggtgttgggg caattcagtc tttggtatgc 58260 taatttggat gagattcaca cttgggctgt tggagaggag tgggtgaacc tgttgagtta 58320 atcagcaact ccaagaggtc catttcccaa gcatctttcc ttccataact tcacagtaat 58380 tttcgtttcc ttatgtctcc tctggccaat atttttctac ttctggggta ggcggtcaga 58440 ggaaagagaa aaaaaggaaa atggtgaagt tggacccact gtcttggacc tatgacgact 58500 cctggcagag aaaggttttc ccacttttcg tttttgttct tgtgaactcc ctgagcagcc 58560 actgtcatga caacatgatg gtctgagagg tggagtagaa gagattggag aaaagggcga 58620 cagagtgaga ccttgcctct aaaagagggg ggtggtggtg gagggatggg aggaaagggg 58680 gattcttcac tcttgagttc cgttttcaat cctcgaactt ttcctggagc ccgcagtctg 58740 caccacagcc tcacttctgg gtttctgcct gtcttaaatt caggcctggg gataagtgag 58800 tggtaaaaat taaaattcat caccaattta gtagtacttc acagtccagt gttattcctt 58860 catttctgtt actacttagt cctcaaacag ctgttccata cattttatcc aagttttata 58920 gctatattca gtaggagaga cagggcagaa aatacttttt ctttcctgaa aatggaaccc 58980 taatgggagc ctgatgaatt ttttaattga agccaaaata aaaaaattaa tatgtgctca 59040 taaattcata tttatactca taaaatatga cattcaaccc aagttcttca ttttaacact 59100 tacgcctttt tttttgagac agagtcttgc tctgttgtcc aggctggagt ggaatggcat 59160 gatcttggct cactgcaacc tctgtcatca gcgttcaagc aattcttgtg cctcactacc 59220 gggtcttact acattgccca ggctggtctc gaacttctgg gctcaagtga tcctcccgcc 59280 ttggcctccc gcagtgctgt gattacaggc ataaacctct acaaatttta atctacaaaa 59340 aacaaaatta tattcgcttt acctgtgtga catttgaata atgacggtcc atgcaggctt 59400 tacatttcac ttttatgaac taaaaaaaaa ttgagcctcc acagggcaag tcctctgctg 59460 tgcatggaag ataggcaggt gttcaaagca tagaaaggta ctgctgcccc aggtaatgca 59520 gtcaagaggg aattcaagca tatggaggtg attttcattg ctatcaagag tgtggtttaa 59580 aaagtcacag taagggctgg atgtggtggc tcatgcctgt aatctcagca ctttgggacg 59640 ccaaggcagg tggatcacct gaggtcagga gttcgagacc agcctggcca acatggtgaa 59700 accttgtctc tactaaaaat acaaaaaaaa aacaatgagc tgggcatggg ggtggacacc 59760 tgtaatccca gctacttggg aggctgaggc aggagaattg cttgaacctg ggaggcagag 59820 gttgcaatgt gctgagattg tgccattgca ctccagcctg ggcaacaaga gcgaaactcc 59880 gagagagaga gagagagaga gagagagagg gagggaggga gggagggagg gagggaggga 59940 gagagagaga gagagagaga gagagagaga gagaaagtca cagtaaggca ccctagcaga 60000 gtgaaacaaa aactaaaaaa aaatcgtgtt ccagcatagg cctgagcatt taaaaatcga 60060 agaaccgtgg aaatattaac aattacataa agtgcatcta gattttgaag tcatttcatg 60120 caatattcat gagttctggg tttatcagtt attcctcagc tttatttggt gtatcagttt 60180 taggaatgtg tatgtataat cgtcaagtct tctatctgaa aggtaccaga acaaagcctg 60240 gctttaggat cagatcctgg gcaggcaaaa gagcgctaga ggcggaacaa gatatccttc 60300 ctatctgaag tggccatggg ttttcaactg acagccttct cctcatccac ttccaccttc 60360 cccgatgctc tcagaggtag actatgaagg cctctcccta accactttct agctgcctct 60420 tcatatcctt agtgtatcat ttctccaagc tgtaggtgtc ctgctaattg attttgaatt 60480 tttatgttct tctgtgtgcg aatgattaaa tattaaatac aaaagtcggt tcatttgttt 60540 gttttttcca ggcttgtaat ctctaacttt catttttgct acaaagcctt taaaaaaaaa 60600 attcagttac tctagattca gattttaatt aaaatttatt tttgaaggta aacatcttac 60660 ataaaatttg gctaaaaggg aagaaaaaaa actacctaaa gtttatgtgg tcatcctact 60720 tgcaatattt tagcaagcat gatttttatt taatgagttt caaaaatttt gacaatgaat 60780 actatcacag agactaagag tgtgtgattt cttccacttt catagcacag atgctcctcg 60840 acttacaatg gggttatgtc cccaataaac ccatcataaa ttgaaagtat cttaagttgg 60900 ccaggcacgg tggcttacgc ctgtaattcc agcactttgg gaggctgagg caggtggatc 60960 atgaggtcag gagttcgaga ccagcctgac caacatggtt aaatcctgtc tctactaaaa 61020 atacaaaaat tagctgggcg tggtggtgca catctgtaat cccagctact caggaggctg 61080 aggagaagaa tcgcttgaac ccaggaggca gatgttgcag tgagccgaga tcataccact 61140 gcactccagc ttgggcgaca gagcgagact ccatctcaaa aaaaaaaata tatatatata 61200 tagtgagttg aaatgcattt aatatatcta atctattgaa tatcattgat tggcccagcc 61260 ttgagcactt aaatttgctc aaaacactta cattagccta catttgggca aaatcatcaa 61320 acacaaagtc tattttataa taaagtgttg aatatctcat gtaattcata aaatactgga 61380 agtgaaaaac aatggttgtg tgaattctca aagttcagtt tctactgaat gcttatcact 61440 gtcacaccat cataaagttg aaaaattgta agttgaacca tcttaagttg gggactatct 61500 gtactgtgaa attccaactt ctggacagtc aagaaggaag ccagtaaaat cagaaaccag 61560 cggctttgca gccaagtaag cagggaggcc aagcgtattc cttggatggt ctgcggtggg 61620 cagtctctgc caggatgtgc ccacttagca cacacagccc tgtacatcag cctgcaggaa 61680 aggcaccttg gccagagcct cgggctcacc ctagagcact atagaaaggt catctggctg 61740 tctgggagga cagtagccca caggggctga agctgggcac acccactggg tggctcaggg 61800 ccagttttat aatccctacc ccctcaacaa acacactcca ctcttgacca ctgcactcca 61860 acctctgtcc ctgcatcctc caccaggctt tacacctgca attgcacttt ggataataac 61920 aggcatcatt ggcaatatct tacactctat catttcagat aaagccttga aaaatatgtg 61980 caattatatc tgtgcttctt tgtggatata tgttttatta tattcactat atgattataa 62040 taatattagt tactactagt atttatcaag aatgtagggc tgaagctggg cacagtggct 62100 catgcctgta attccagcat tttgggaggc tgaagcaggt gtatcacttg aggtcaggaa 62160 tttgagacta gcctggccaa catggtgaaa cctgatctct actgaaaata caaaaattaa 62220 ccgggcattt atgcctgtag tctcagctac tcgggaggct gaggcacgag aattgcttga 62280 gcctgggagg tggaggttgc agtgagctga gatcgtgtca ctgcactcca gctgggacaa 62340 cagagcccca ctctgtctaa aaaaaaaaaa aaaaagaatg tagggctggg catggtggct 62400 cacgcctgta atcccagcat tttgggaggc tgaagcagga agattgcttg agctcaggag 62460 ttcaagacca gcctgggcaa catggcataa ccctgcctct acaaaaaaaa aaaaaaaaga 62520 tctatataca cacacacaaa tgccaggcat ggtgacacat gcctgtggtc ccaactactt 62580 gaaaggttga ggtgggagga tcgcttgagc ccagaaggtc aaggctgccg tgaggcatga 62640 tggatccacg gcacttcagc ctgggtgaaa gagcgagacc ctgtctcaaa acacaaacaa 62700 acaaaaaggg tgtagtatat tcctggtatt gattgtgctt ttcatagttt aaaagtaaga 62760 cttggtgtaa aggtatgcat tgtgtagtat aaatgcacag agaggaaagg agagattggg 62820 tacaaattca ggaaggcatg aagtgttgat gtcatgacac ttagcccatc cttgctctgc 62880 acagaccacg tttctcacca ctgtgctggt atgtagacac cagcatgatc ttctgaagcc 62940 tcggataatt tggtgtggat agctttcttt tggattcttt taaattttgt tatcttaaag 63000 ctttccatag tatttcatat ggataggcca cagttacttt ccatttacta ttatactttt 63060 atatattttt tcttattttg atatgagaaa caatgttgga ataatcatgc ctagacataa 63120 ataagccaat ttcaaaatgt ttgtagggga gactcatagt gttgccagaa aaaggggccc 63180 tgacccagac cccaaaagag ggttcttgga tctctagcag gaaggaattc aaggcgagat 63240 gcagagtgca ctgaaaagag agagtttatt gaaagctact cagctataga gtagagcatc 63300 ctcagaaagc aagaggagaa atgccttgta tttaagtttt ttttatgtaa gtgtcttgtc 63360 tatgtaaaga ctaaactaag ctgtgtctac gtgcagatgg gttgagagca tgacaaaatt 63420 tactattctg ttgatttaaa gaaaatggtc cttgacattt tagtaagtac atcaaagcca 63480 taactgtaag taacttgaaa gcatatattg ttatgggtat tgggacatct ggattttgtg 63540 ttgttgtagg agtgtatcct tgcaccggta gcctaggtat tgttaagctg tttcctcaat 63600 tataaacatg actatgggtt gtgaccagca aggaatgtgc cttagttaat ctcaagatgg 63660 agctgaactt aaaatgccat tactttggct ctaaccagct cctgcttcca taacagtggg 63720 gtcaaaaggt gttcctttaa aatcttccta gacactgcca aattgctttt ggaaacttct 63780 cacctggtga gatggcatga gtatctttgg ctcatttttc tacatagact tggaaacagt 63840 tttatgttta taaaatatgt atcacctcat ttataaattt gtttgaataa tttaaccatt 63900 ttgcttttat tagctatttt gctactctct gttttccttg cctgagtctt tcccacatct 63960 ctgcaacatt gtatcatttc ccacacctaa aaccaaagag ggacaggcaa gccagtggag 64020 agagcagagg ctgatgagaa cgaaggattt tccaggaagg aatctggggc tgtgtgtgtg 64080 tgtgtgtgtg tgtgtgtgtg tgtgtgtatg tctgggtgtg tgaatattgt ttttattagc 64140 ctgtagccca cgtgttgcat ggccatattt ttactatcag gatataaaac acacttacac 64200 acagctgcat acaaatgcaa tgagtttatt tttcatatac atttcaaaat aatagcgtga 64260 acagaccaga actcttcttc aaagttcaag aatgtcctca tggatccagc atccgtctgg 64320 tttctgtttc tgcattctca gtacatagcc tcacttctct ttctccaatt ttggaggatg 64380 tgtaaaaaat tttattctta accaaacatt agtcaggctc cggaacgttc tcttaactcc 64440 atccatgcac tttcttgtaa aatgcagttt taacaagaac actgctaagt tagtttagca 64500 agacccccac accttagaca tctgatcacc ttctatatct tatcaggttc ctcatcctcc 64560 accatccctt aagtgatcat cccagcttgt cttcagcaag aatcctatta gatcaattta 64620 gccagaatcc ctcttgcccc tgatgttaat tcttagtaat tttccaacca ctagtcccca 64680 ccctgttcct tggctataaa ttgccacttg cccatgctgt acttagagtt acttagagtt 64740 gagtctcact ctctcccaca ctgcaaggcc ccattacggc ggtccctaaa tctattgcag 64800 tggtcccgaa taaagtcttc cttactatgc attaacacgt atcattgaat atgacttttt 64860 ctttaacaga tactttgacg aaggtaattg ggactcccat caagtctcca cacagctagc 64920 agccacgtgg ggcacttctc caggtaagga ttgtccctgt tccacttatg ttcctgtcag 64980 taaaatggta ggttcagtgt caggctttac cattttcttc agggagagac ccatctgata 65040 tttagtcagc catcagatgg gtccagccat agcacacatt agctgtgaca tgacgtcgtt 65100 tatgacaatg actttgagca gagttgcaca cctaaaaagg gactcaatta aaattatcat 65160 tcattttagt tatttctcag atgcatttat tatttccatt ttccaaaact cctaatgtta 65220 catttcttct tcacatgtta gatatgaaca aagtaagact aactgtggcc acatcctctt 65280 tacttaggac cctacccaaa gtggcaggaa tgggatgtaa agtgacataa tcagacacag 65340 tcaaactggc ttttaatcgt taagtatcat tgtcatctca aagcacttgg catagttact 65400 gaccccttaa atgtcctttc tccatcttat cttctccttt gttctctgta tcatcttccg 65460 gtcctataga aatatatccc cacgagcaca cactgaggtc tttttttttt tttttttttg 65520 agacggagtc ttgctctgtt gcccagactg gagtgcagtg gcatgatctc agctcactgc 65580 aacctctgcc tctcgagttc aagcgattct cctgcctcag gctcccatgt agctgggatt 65640 acaggcatgc gccaccatgc ctggctaatt tttgtatttt tagtagagac aaggtttcac 65700 catgttggcc aggctgctct caaactcctg acctcaggtt atcctccggc ctcggcctcc 65760 caaagtgctg ggattaccag catgagccat cgcacctggc ctcactgagg tcttaatgct 65820 gagttgaact ttgtctctgg ccatgagcat cagtccatgt attataatag gtttgggttg 65880 ggtgtggtgg ctcacacctg taatcccagc actttgggag gccgaggcag gctcacaggt 65940 aaacaattta gacaaagttt tcacattctc tgagatttgt atacattgga gattcagaaa 66000 aatgtaaccg aaaattaaac tataggtgga atagctgcct ttgggggctg agaagacagg 66060 catcagacct gggatagaca agggaggcct cttgttcctt gaaatgatac cccagcccat 66120 gaggtctgca tgccaggaag ccaaatgagt gaggatggtc tgtgtccgct ggggaggtcc 66180 ctggatgttg ccaagaggga tagggtctgg gaaagagtga ggatggagtc aggcagagag 66240 gaccccccag gctcatggat ggactgacct gaggacttat attaagtcat aggacagtag 66300 agaaagtaag agccaagcat aatgtaatcc taacaatgta aaaagtatta atcattttat 66360 tattagttaa tgtcactgaa ctgtacactt aaaatggcta aaaaggtaaa ttttaggtta 66420 catatatttt accgtaatat aaaatgacaa atatattaga aatgactttt tttttttttt 66480 gagatgtagt cttgctctgt tgcccgggct agaatgcagt ggcacaatct cggctcacca 66540 caacctccgc ctcccaggtt caagtgattc tcctgcctca gcctcccaaa tagctgggat 66600 tacaggtgtc cgccaccatg tccaactaat ttttgtattt ttagtagaga caggtttcac 66660 tgtcttggcc aggctggtct cgaactccag acctcgtgat ccacccacct cgggttccca 66720 aagtgctgag attacaggcg tgacccacca cgcctggcca ggaatgactg tcaactatat 66780 tttcttaaca tatgtattcc tacacaacat cagttttgta atagtttatt tttgttttgt 66840 tttgcaattt ttttctttta ttgtaaggaa agaagtacat tttttcagcg tgtaagaatg 66900 caaaagtaat tatcagatgt ttgtcacatc ttaacaaaat aggaccttat tttcctagat 66960 gttgctgcat tcagtccctt tcttggtatg gtaaaagcat caatcagcca gggaggcaac 67020 tataaataca gaagagcagt ttcctacaga tagtcaacca tgctacccct cttactgact 67080 taattttaat attggagcct ggcacaatta acctagtttc ctcgtaaaca caagaacaac 67140 gtactgcaat caatgtaggc atatacaggc tcttaaagtt ctgagaagca gcaagtaagt 67200 tcatcattta ctaagatcct tgacattctt ctgtttctgt gaaatttatg catctgtgag 67260 aagtttcttt tcttttttta tttttttttg agacagagtc tcgctctgtc acccaggctg 67320 gagtgctgtg gcacaatctt ggctcactgc aacctgaacc tctggggttc atgccattct 67380 cttgcctcag cctcccgagt agctggaact acaggcacac gccaccacac ctggctaatt 67440 tttatatttt taatagagac agggtttcac catgttggcc aggctggtct cgaactcctg 67500 acctcaggtg atccacccac cttggccttc caaagtgctg ggattacagg cgtgagccac 67560 cgtgcccagc tgagaagttt cttatactag aagaaaaaga aaatttgatt tattttaaaa 67620 tataatggtt tagtctgtag caagtaatat taattttttt atttttttat ttttgagacg 67680 gagtctcatt ctgtcaccca gactggagtt caatggcacg atctccgctc actgcaagct 67740 ccgcctcccg ggttcaggcc attctcttgc ctcagcctcc tgagtagctg ggactacagg 67800 cgcctgccac cacgcccagc taattttttt ttgtattttt agtagagaca gggtttcacc 67860 gtgttagcca ggatggtctt gatctcctga cctcgtgatt cacccgcctc ggcctcccaa 67920 agtgctggga ttacaggcat gagccaccgt gcccggccct aacacgaatt cttaagagag 67980 gtgaaccagg gatgggattg tggatcaatc atgcaaagac cgactcctct gggcttcatt 68040 tcctccatac tgaatgtgca tccctacatg ttcatgttgt tgtttcatag gtagtgcagg 68100 gggtcagaat aggatacccc tggctgggtg tggtggctca cgcctgtaat ctcagcactt 68160 tgggaggcca aggcaggtgg atcacctcag atcaggagtt tgaaaccagc ctggccaaca 68220 tggtgaaacc ccttctctac taaaaataca aaaattagcc gggtgtggtg gtacacgctt 68280 gtagtcccag ctactcagga gactgaggca ggagaatggc ttgaacccga gaggcagagg 68340 ttgcagtgag ctgagatcgc acctctgcac tccagcctag gtgagattga aactccattt 68400 caaaaaaaaa aaaaaaaaaa ggatatcctc aattgcggtg ccctggcata ctgagtattt 68460 taagctgaag gaaattgaga aaaccatgga agcaggaagg ccactctctg atttgctccc 68520 acttttctcc cctgaagcag gtcataaaag aattatctgc cctacctgtc ctgaaagtag 68580 gtcataatgg gaccctcatt tcagaggagt tctgccctat ccctggatac caacaaagat 68640 ctgaacaaac aggtcttatg aatttctccc caggtaatta ctattagatg ataccctttg 68700 ttccccaaag ctatttcttc aaaactgtcc ataaaaatac acctatccag ctgggcacag 68760 tggctcacac ctgtaatccc agtactttgg gaggctgagg cgggtggatc acgaggtcag 68820 gagttcaaga caagcctgac caacatggtg aaaccccacc tctactaaaa atacaaaaaa 68880 caactagctg ggtgtggtgg cacaagcctg tagtcccagc tactcaggag gctgaggcag 68940 gagaatcgct tgaacccagg aggtggaggt tgcagtgagc cgagatcgcg ccattgcact 69000 ccagcctggg caacagagcg agactctgtc tcaaaaaaca aaaacaaaaa caaaaaaaca 69060 aaaaagcccc acctatccct tggcctttgc atcttgattt ctgaagactc acatgtcatg 69120 taaaacttac gttaagtaaa tatattatgt ttttctcttg taaatctgtc ttttgtaatc 69180 aggatctcag ccatgatgca ttttggcttg tcagaaataa tcacaacatg tggagaaata 69240 gataaaatgc catttttaaa attattatta ttttttattt ttttgataga gtctcgttct 69300 atcgcccagg ctgcagtgca gtgtcatgat ctcagctcac tgcaacctcc accacccagg 69360 tccaatcagt tcttgtgact cagcctcccc agtagctgtg atttcaggca tgcaccacca 69420 cgcttggcta atgtttgtat ttttagtaga gatgggatct tgctatgttg gccaggctag 69480 cctgaaactc ctggcctcaa gtgatctgcc cgccttcgcc tccttaaatg ctgggaatac 69540 agttgtgtaa tggtattttt ttttgagaca aggtctcaaa atggcatttt ttttgagaca 69600 gggttgttgc tctatttacc aaagactata caagattatg tgaacttaaa ataatattcg 69660 ggttaatttc tgtatttcta agttttagga atacttagtt atgtaagcat ttacttccct 69720 ttaagtcaat taaatcctct tttaaggaac tttataaatt aatttggtag tatcattggg 69780 cccagtagag tttttttttt cttttttttg agacggattc tcgctgtgtt gcccaggctg 69840 gagtgcaatg gcgcaatctc agctcactgc aacttctgcc tcctgggttc aagcgattct 69900 cctgcctcac cctcccaagt agctgggatt gtaggctccc gccaccatgt ccagctaatt 69960 tttgtatttt tagtagaaat ggtgtttcac catgttgatc aggctggttt ccaactcctg 70020 acctcaggtt atccaccctc ctcggcctcc caaagtgttg ggattacagg gatgagccac 70080 cacacccggc aaatttcttt taagatattt tataaattaa tttggtaata ccatcagagg 70140 cagaaaaatt tcacacagat ggagagacat acataaacat acaggcaaat atcaaaagag 70200 atcttctagc tatcattcta aaatcttagc catgaatcag aaacacatag taatacaaag 70260 tcactgtttt atatgtaaca gttatctctc atattttctc catttcatat tttttcccta 70320 ttgtccctgg taaatgggac aagttaaggc tatgtactaa atattaggcc taatgctttt 70380 taccaatatt catggagaag gtttttaaga tcttcatttg ccctgtgaag cccttttgaa 70440 ggctgtggac taaatgttaa atgagtcact gcaaagacat ctaacagcta tcgaaatgtc 70500 tccaccaccc atctgagtgg ataaaatatc cagtctattt ccaaatagtc tttttttcct 70560 cttcagcctt ggtacttact tttggaggac tctgagtccc ttgacagcag ggtggactaa 70620 agtttaagag aagaagtctg acaggggagg aagacagaga gatggagaag gtaggagttt 70680 gaagggatca tatccaggac tcaaaggaac tgaatggaag attgaaagtg gcaagagtag 70740 gaaggaggaa cagaaagagg gggaaggaag aggtcttaag ggaaccagct gggggagata 70800 ttaaattccc caaagaggct agtgaagctc caaattatcc ttagcaaaat caggccgggt 70860 gtggtggatc acttgaggtc aggagtttga gaccagcctg gccaacatgg tgaaacccta 70920 tctctactaa aaatacaaaa attagttggg tgtggtggca catgcctgta atcccagcta 70980 ctcgggaggc tgaggcagga gaatcgcttg aacctgggag gtggaagctg cagtaagcca 71040 agatagcacc actgtacttc agtctgggtg gcagagtgag actccatctc aacaaataaa 71100 taaataaata aataaatatc cttagcaaaa tcatgccaaa aagagggagg taggcagaat 71160 tgtgaaagct tatagccaac agaggttcaa gaaaaggctt tttgtcaatg gataagttta 71220 catgggaaga tccggatcaa aaggagagaa cagagaggac ttaagaaaat tgttcctatt 71280 ggctgggtgt ggtggcttat gcctgtaatc ccagcacttt gggaggctga ggcaggcgga 71340 tcacctaagg tcaggagttc aagaccagcc tgatcaacat ggtgaaaccc cgtctctact 71400 aaaaatacaa aaattagctg ggcatggagg tgcacgtctg taatcccagt tattcggagg 71460 ctgaggcagg agaattgctt gaatctggga ggcagaggtt gcagtgagcc gaaatcgagc 71520 cactgcactc cagcctgggt gacagagtga gactctgtct caaaacaaac aaacaaacaa 71580 acaaacaaaa acagaaaaga agaaaagaaa gtttttccta taagtctgta actatcagct 71640 tcccattagg ccaactattg atcatagagg tcttaaaaaa tcctttcagg ctgggtgccg 71700 tggctcatgc ctgtaatccc agcacattgg gaacctaagg cggtaggatt ggttgagccc 71760 aggagttcca caccagcctg ggcaacgtat tgagacctca tctttactaa aaataaacaa 71820 aattagctgg gtgtggtggc atgctcctgt agtcccagct actcgggagg ctgaggtgag 71880 aggatcacct gagcccagga ggtcaaggct gcagtgagct gtgattgtgc cactacactc 71940 cagcctgggt gacagagcaa gacactgtct caaatatata taattttttt caaatatctt 72000 atcaggtttt ggtcaagagg aaaggtaaat attcctgata gtacattccc attaaaaaaa 72060 aatgtacccg ttacaagtga cttggaacca aaatccatag attctttcat ggttctttat 72120 cggtatggtg atagggtttt catattcatg tgtgagatgt gcctccctca gtccttgtta 72180 tgacatcatt acgtgtctga catgacaaaa aggaaaagag aaaaaggtgg agaaaggtaa 72240 aaaataggaa aagaaaaact gaaggaaaaa ggaaaaaaac ccaatccgta agccttttat 72300 gacttaccca tgaatgcaga ggcatcttca aagagggtgc aaaaaatgca gccctctaaa 72360 gatgccaaac cactctcaaa gatagccaaa agaaaggcag gcctagatac tccccctgag 72420 agctggcaat agatgttagc tgcaaatggg ttgcaaccca catgtctgtc cagctgtatt 72480 cccacagccc cccaacctga tggttggctg cttgcacaca caagaaccaa caacttgtac 72540 gccccatcaa gtggaaaacc aagccaaatt cttttttttt tttttccttt gagacggagt 72600 ctcgctctgt cgcccaggct ggagcgcagt ggtgtgatct cggctcactg caagctctgc 72660 ctcccaggtt cacgccattc tcccgcctca gcctcccaag tagctgggac tacaggtgcc 72720 cgccaccacg cctggctaat tttttgtatt tttagtagag acgggctttc accatgttag 72780 ccaggatgtg tcttgatctc ctgacctcgt gatccgcccg cctcggcctc ccaaagtgct 72840 gggattacag gcgtgagcca ccgtgcccag ccgaaacaaa gccaaattct tgacacaaaa 72900 tgacagaaac agaaaagcaa tagctgctcc tgggagggaa aggatcaata accaataggc 72960 accacaaaat caagctacag tcacaatcta gataatgaat ttttataatt tttttcctat 73020 ccatctgcat tgggaaaata agggacaagg agtttttact ttcttctctt gaccaggaac 73080 tactgacaga gatctgggag agctgacttt ggtgaaaatt ctcaccttgc acaggcttgt 73140 gtctgttttc cagaatccta cctgcagact ccagaatgaa gtgtcccagc tgtccctttc 73200 tcgttgccag aaacttctac ccttctcatt cctttgcttg tccccctgta acaagagaca 73260 gattaatgag agaaaatcat gcaagttgat ttactgtatg ttttatgtaa catgagtctt 73320 cataagaaaa ctaagcccaa aagaagcagt taaacctgag tgtttttttt gctggtctga 73380 tgaagagcga agagtcatgg agaaatgtaa tgggaccaaa aggtgtcagc taagtgtaat 73440 aaactggggg aaacagcaag ggctattcct tcagattcct ctcagtgtcc ctgtgtcttc 73500 agagataaag atcttttcct ctgggtaaag cgtggcagct ctcacatgag ggttttatta 73560 cttgcttcag cagaaagtca aaaagccctt cccaggtttt atgacctctt tcagcgaaag 73620 gtgagaaagt ccttcctaca catttggttt ctgaaattcc ttcagcttaa aatattcatt 73680 atgccaactt tccatatttt gggttggcat gtcctgaata tattgtcaga gcattacaga 73740 aaaaatacac ccaaacacac acacacacac acacacacac acacacacac acacggacaa 73800 cacattccct atgactatct taaaattgat taacctcaaa catttaattt tggatgactg 73860 agtcaaaaag agaattgaaa ttgccatcac atatctggtc aagctgaaag atggcatttg 73920 gtattggaaa ttgatggctg ctggtcattt aacacccatg cctcagttac atatctggct 73980 catgagataa gaatgctaaa cagtataaac aagacacctc agtatgaaaa cgttctgccg 74040 ttacaaaggt actctctttg tgttactctg cattctctcc cagccctgta gcaatttatc 74100 ctttgtccat atattgaaga tagatttgtt tacatctact cttagccttc ctgaatatcc 74160 tttgctccag gagagcctta agccaagggt agaaatgaca agacagactc tatgtttgca 74220 gaacaccaca tagtcacagc gatgcaaatg gaaaggaaaa tatgagaaca aggtctttca 74280 atccagattt ggcctatgtt tgtattaaag gtgttattcc catgtaagac cttaagacat 74340 aatattaata ataattcagc tatgaaaggt tcatgttgag ttctacttgc atgggcaagc 74400 tattaggtag aagttaaaga tgcacagaac acattagttc tttctaggta tatccttagc 74460 agagcaaaat tgcaacccaa gttagaacag gaaaaacttg atgaagcatg aaattaccag 74520 ctggtctgat gggagatatg atgtggccct gaggtacagt aggtggtgcc tgaagcatgg 74580 tgacagtagt ggaaacacct tagggtgacc cacaattagt cactctcatt caattccctt 74640 tccttgggtg tgggaagaac ctgccaatag catgtggcaa aggatatcgt tactgtgttt 74700 atgctatgtt atatgtcaaa agtgaagata tagtgcagat gtaattaaag aaatcagttg 74760 gctttgagtt cattaaaagg cagaatagcc tatgtagacc tccccttatc agatgagcca 74820 cttaaaatgg ctcctaggca gatcacaagg tcaggagatc gagacccccc cgccggctaa 74880 cacggtgaaa cctcatctct actaaaaata caaaaaaact agctaggtgt ggtggcgggc 74940 gcctgtagtt ccagctactc gggagactga ggcaggagaa tggtgtaaac ctgggaggcg 75000 gagcttgcag tgagccgaga tcgtgccact gcactccagc ctgggcaaca gagcgagact 75060 ccgtctaaaa aaaaaatggc tcctaggcct tccctgatgt cagggaaaat agaaaagact 75120 ctgtctcttc actgttgcct ttgaagaagc aagctgccat gaattctata gccattgtaa 75180 aatgaattct gccaacaagc aaatgagctt aaaaagtaac agagtctgcg cacagtggtt 75240 cacgcctgta atcccatcac tttgggaggc tgaggtgggt agactgcttg agcccaggag 75300 tttgagacca gcctgggcaa catggtaaaa cttcatctct atagtaaaat acaaaaatta 75360 cccgggcaca gtggcatgca cctgtagtcc tagctgctca ggaggctgag gtgaaaggat 75420 ggtttgggtc caggaggcag aggttgcagt gagtcaaaat cacccctctg cactccagcc 75480 tgagtgagag ccagactcta tctaaaataa acaaaaacaa aaacaaaaac gtaatacagg 75540 ccactgacac cttgactgaa tccctgtgaa atatttcacc tgaaaatcca gctaacctgt 75600 gcccactgac ccacaggaat ggagataata tatttacatt gttgtaaact gctaaattga 75660 ctggatgtgg tggctcacac ctgtaatccc agcatcttgg gaaaccaagg tggggggaat 75720 cacttgaggc caggagtttg agactagcct gagcaacgta gcaagaccct gtctctacaa 75780 aattaaaaaa ttagccgagt gtggtggtgt gtgcttgtag tcctagctat tctggaggtt 75840 gaatgggaag atttctttag cccaggagtt cgtggttaca gtgagctatg atcacaccac 75900 tgcactccag aatggatgac aacgtgagac cttgtgatat ggtttggctg tgtctccacc 75960 caaatctcac cttgaattat aatcccatgt gtcaagggtg gggccaggtg gagataattg 76020 aaacatgggg ggtggtttcc cctatactgt tctcttggtc atgaataagt ctcattagat 76080 ctgatgcttt tataaatggg agttcccctg cacaagcgct cttgcctgcc accatgtaac 76140 atgtgccttt gcttctcctt tgctttcctc catgatggtg agggcttcct agccatgtgg 76200 aactgtgagt ccatgaaacc tctttcttta taaattaccc agtctcagat atgtctttat 76260 tagcaggctg agaatcaact aatacaccct gtattaatgt attaatacat gaataaaaaa 76320 agttgctaaa tatgtagaac tacactctgt gtcttccctt tagtgttagg aagatcaaat 76380 aggcactaca agagcatttt cttggtaaat ggtatctaaa ttccctctta tcaatggcaa 76440 ttactcattt ggactgctaa caccataggg gcaaaaatcc tgacatgtat gaatcttgtg 76500 ggagaagcac ttggaaaaaa aacaaaaaca aaaacaaaaa acagagacaa acatttctga 76560 gcaaaaatgc aagcttttta aaaaaaatag tttgttttga tcagttcaca tcatgtaggt 76620 catttcatcc ggcctcattg gcatataagt agtatatatt gagctaggcg tggtggctta 76680 cgcctgtaat cgcagcactt tgggaggccg aggcaggcgg atcacgaggt gaagagatcg 76740 agaccatcct ggccaacatg gtaaaacccc gtctctacta aaaatacaaa aattagctgg 76800 gcatggtggc gggctcctgt agtcccagct actcgggaga gtgaggcagg agaatcactt 76860 gaacccggga ggcagaggtt gcaatgagcg aagatcgcac cactgcaccc catcctggcg 76920 acagagtgag atctgtctaa aaaaaaaaaa agtagtatat attgaaagta taaaggggtg 76980 aaccactttg aattgcgtat gacaaaagaa gctcagagtt caggtgaaaa atgtgttatt 77040 acaaactcaa ctatcaattt aatctgtctt taatgtatga gtcaaaatta agtgttttct 77100 gttggggtga tcggacccaa caccaggccg tgggggcgat gaagtcccac ggagtcaaag 77160 gaatgagaaa agacaagtta agagagaaac tgggaccagg ggccaatgct agtatggagg 77220 ctgcgaaggc cccaagctct gggaccccat gctatttatt ggtgatcaaa caaagaaaca 77280 ggtggcgagg ctgtgggggt tgaaaggaag tggtgtatca agcaaatgag ctacagctgt 77340 gatggtttag cattttcttt gaaacatatg gctacttgag ataatgggag tgctagaagc 77400 aaggagccag caagtctaga cacattccaa aggccacaag gggttttaga ccctggaccc 77460 cagacacgtt ccaagactct tttacattat gtcagacatc caggccctgc ctcaaattct 77520 ctcccaacac tcagcttttc tcccaacact ttctattaca aacatcaacg gaaaaatcaa 77580 tgatctgttt aaaatattgt aaataccatc actatgtttg aagatatgtt ttaatttttt 77640 attattcctt taattaaaag aactgtatgc caattaataa gctgttgcct tttagatcaa 77700 aattaatcat tcattgcctg ctctgtgaaa attgagtcag atacccttaa aaatatattg 77760 tgttgcaata gtaagttttt tcagtaattg aaggtggttg gacattgtaa aaagagattt 77820 tcctttctga ttccactgtg gtctctcagc cgtttcccat agcatgcatg cctttctcca 77880 gcactatatt tctacagtat gcatgagcaa tcctgcagca acaatggctt ttctagcatc 77940 aggctcctac aacgcatgac agtcagcagc actagtggtc agccacttcc tatatcccct 78000 acccttaggt ggtttctagt gtagtgcttc caataatata cctacctgtg aacacctttc 78060 cctggcacct aagtgggaag atttctggaa agttccactg gtgccgcaca ctgtgactat 78120 tctgtgtagc ctctaacaag ctctggattg caatccactt atagtaaata aatgtccact 78180 tcaaacattc cctcctcaaa ttcttgtgtt ttgtctgcct cctgattgga ccctcactga 78240 aagaattaat gctggcattg ttccaagaga tatttccaca gagatgaatc tgggaggttg 78300 tgttggtcat tcctttatgt ttgggcacat tccacagctc cttgtcaatg tgcaatggga 78360 tactagcaac ctatgacatg cagtggtatc acaattaatc aagcaatgac ctgtggttga 78420 ttgtggcaaa gtgccaactg aaacacgtgc cttgggagcc cgagtgactg ctgcactgaa 78480 tgttatggca gtcaagataa ctgtaaggac tgtggggtgg aatggattca gttgagggtc 78540 cttgagtgat tacgaacaga aaataacaag cttaggttcc ttaattctca gttcaagcca 78600 cggtttgaaa acctgagaac ttccatggcg actataaagg aaattcattt gttgtagctg 78660 cagggctgat attgttaaat atcaaaacca agaatgagat cctgaaactt ggaatgggtc 78720 aggaaacttg gaatggggga atctgtttag actcagttga aactgaccat ctggaaacag 78780 aaagtcaggc tgagcctttc ttaccagttt aagtagcttg tctctattgt ttgaagaaaa 78840 tatctttccc ttgcacaaaa gctgggttag ataccattaa aggggatgcc catttttctt 78900 aaagtcccct acaaatcatc actttttgct agtagcatga ctagacccca taactaggat 78960 tgaatagcaa cctattccta agggataggt acacactatg acctgtagga aacagctaca 79020 tgcaaaagga actgtgacat atattggaag aaacctgggg aatgttggaa gagcattcta 79080 aggccgttat actaaggagg acaaaatata acagtagatt gggttaatta atctcagtgc 79140 tattactggg gattcaagat ttattgtgct gcaggcatgt ggctcacacc tataatccca 79200 gcactttgga tgccaaggca ggaggataag atgagtccat aaatttaaga ccggtttggg 79260 caacataaag agaccttgta tctacaaaaa ataaataaat aaataatcca gtgagagtgg 79320 tgcacctgta gtcccagcta cttgggggct gagatcagag gatcacttga gccctggagg 79380 ttgagggtgc agtgagctgt gatcatgcaa ctgcagtcca gcctgggcaa cagagccaga 79440 ccctgtctca aaaaattaac aaaaaaagat ttattttgta gttctcctgg tagagatctt 79500 tcatctcctt ggttagatgt attccttggt attgccgtct taggtagagg aagagggctc 79560 aaacatcttg cttatgtgat aactttgcca aagacacaat gtacaatttg ttttaaaggc 79620 cagtgaggga tgtaccagta atcagaatgt tttggcaaac agaagacttt ggtggtagct 79680 aactgatcac agggtcccta gaatgaaata gatgagaagc atacttagag tattgtttga 79740 tctctatatc aagaaaagtt ccgggtctgg tagtcaaatg ttcaacagat gcctacctag 79800 ctttcaaccc taagtcaatt cacagttgca gagtgatacc acacggacca tgaaaagaac 79860 acttgtttgt atgactgaga caaaaaagaa tgtcatcgtg ttctacctta cctgggaata 79920 tgctcaattg gtgacaaaat tgttgccact ctgtgcatga ccacaaaagt accgcaggta 79980 ttgattttga agttacacat aaactttagt gagtgggcat atttgcaaat atgtaacctg 80040 agaataatga agattaacta tctttaaaca acataaggag tcaacatcag tttctgaagt 80100 aaaataatga ctaagttaaa ttttcaaggg caaattcaga ttccaagtgc acagaacata 80160 ggaagaaaag gacatgcaaa tcagaaaaat tcacaagtgt aatgaggcga gaagggacat 80220 ggcgcaccaa ttacaaagga atcagaatga tctgttcata gagttgtaaa tggggttgtg 80280 gaggaagaaa tgaggatgaa cagataggca agacaagttc ttttccttct atgtaaataa 80340 gagaaactga gaaattgtaa cgtaagacaa gatctaatat tatttttgga cttcagaatg 80400 gtattgcata aatgcttaat tgttcctgat ttcgggaggg gaaaatggaa atagcatttc 80460 cgttgcattt ttgtgaacaa aatttgagtg atcatgttct ttgttgcatg tggtagatgg 80520 agaggtgaat gaaagattca gctttcttcc tgtacttgag gcatctgtga attgggaatt 80580 cagacaaaca gataagcaac taattctgga tataaaattt gtgatttagg ctatgcattc 80640 tactggggaa tttcagatgt ataggaatgt agttgaaatt taagtggtca gggaatgcta 80700 tctagaggaa gaaaattatg actagagaca agaataaata gtagtaactt aaaaaaatat 80760 atatcaggga agaaaaaatg gatttttgtt ccaggaaaga aactaagtat gaacagatga 80820 tgaactattt caggaactgt gtctgcaatt cgttccttcc agtgggttct tggtcttgct 80880 gacttcaaga atgaagccgt gcaccctggc agtgagtgtt acagttctta aagatggtgt 80940 gtccagagtt tgttccttca gatgctcaga tgtgtccaga gtttcttcct tctggtgggt 81000 tcgtggtctt gctgacttca ggagtgaagc cacagacctt cgcagtcagt gttacagctc 81060 tcagtccgga gttgttcctt cctccaggtg ggttcatggt ctcgccggct tcaggagtga 81120 agctgcagac ctttgcggtg ttacaagcgt tacaagctcg taaaggtagt gtggacccaa 81180 agagtgagca gcagcaagat ttattgcaaa gagcaaaaga acaatgcttc cacagcgtgg 81240 aaagggaccc cagtgggttg ccactgctgg ctccggtggc cagcttttat tcccttattt 81300 ggccctgccc atgtcctgct gattggttca ttttacagag tgctgactgg tccattttta 81360 cagagtgctg attggtgcgt ttacaaacct ttagctagac acagagcact gattgttgtg 81420 tttacaatcc tttaggtaga cagaaaagtt ttccaagtcc ccacccaacc cagaagccca 81480 gctggcttca cctctcagaa ccacagatac aaattatttt atttacctga atcaatctga 81540 aagcatatgc tggggctgga tgttgaggat acttaatggc acattaattc tttgattttg 81600 tatatgttta gatacattca ttagctacag tttgcagctt cctaacaggg attccacaga 81660 tatgactgta aattgagaat tttggtttcc cagtgtctga aaagtggtta acccaaagtt 81720 ttggctttag agaaagagtc tatacaggca aaagcgtaga gggtttggca gagaaaaaac 81780 aaaaacaaaa acaaaacatc ctaagggcca aaggaaatgg ttgcaaggaa aacggtcaaa 81840 aacttgcatc attctcttca tccactcaca ccactctatg caggatccca aatcagtcct 81900 tgaatgtttc ggcacaggtt ccattcatgc tttccaatgg aaacttcatt tggtttatag 81960 gattcaggat tgtggaacca tccggtatca agaaaataaa aggccatgaa aaagtttaca 82020 gaatgttggt ataagcagct gctagggata ttactgagtt ttaatgggag agatagtccc 82080 agaaagctgg aagaagaaag atcagggcca agcgcggtgg ctcacacttg taatcccatc 82140 actttggagg cagagagggg cggatcactt gagtccagga gttcgagacc agcttgggca 82200 atgtggataa accccatctc tacaaaaaca tacaaaaaat tgctgtgtgt ggtggtgcac 82260 gcctgtggtc ccaggtattt gggagactga ggtgggaaga tcacctgagc ccaggaggtg 82320 gcagttgcag tgagcagagc tgaggtctgg ccactgcatt ccagcctggg ctacaaagca 82380 aagtcctgtc tcaaaaaaaa aaaaaagatc ggagcaagaa aaaggaaaaa gatgggtaaa 82440 aacatagaaa cgactaagtt catttcagca ggaatatatt tttaaatata tttcaaaact 82500 gaaacaatgc tatgttttgc tgcagtgtgt gagggaacac aattcaggct aatgcacagt 82560 aaaaatgcag ggaagcctgg ccccgtaacc acttttaata ccacatacta cagttaacag 82620 ttggtgagaa ccctattagg ctgatttcaa ttacaaacat ggatgtacag gagtatgttt 82680 taatggcaca catgcatagt tcatatttta ttagaaaatc tgttcaggcc ggctacagtg 82740 gctaacgcct gtaatcctag cactttggaa ggctgaggcg ggtggatcac ctgaggttag 82800 gagctcaaga ccggcctggc caacatggtg aaaccccgtc tctactaaaa atacaaaaat 82860 tagctaggca tggtgccgcg cgcctgtaat cccagctact caggaggctg aagcaggaga 82920 atcgcatgaa cccgggaggc agaggttgca gtgagccaag atcgggccac tgcactccag 82980 cctgggcaac agagcaagac tccctcttgg gaaaaagaaa agaaaagaaa agaaagaaag 83040 aaaatccggg ctgggcacag tggctcactt ctgtaatccc aacattttgg gaggatcact 83100 tgagatcagg agttcaagac tagccttgcc aacatggtga aaccttgtct ctactaaaaa 83160 tacaaaaatt agctgggcat cagctactct tgaggctgag gcaggagaaa ggcgtgaacc 83220 cgggaagtgg agcttgcagt gagccgagat cgcgccactg cactccagcc tgggcaacag 83280 ggcaagactc cgtctcaaaa aaaaaaaaaa aaaaaaatta gctgggcgtg gtggcatgtg 83340 cctgtaatcc tagctacttg ggaggctgag gcaggagaat cgcttgaacc cagaattcag 83400 aggttgcagt aaactgagat cctgccactg cactccaggc tgggtgagag agcaagactc 83460 cgtctcaaaa aaaaaaaaaa aaaattaaaa attaaatcca ccaaattagc tcaagaacac 83520 ttccttgact ggctcagaaa tcccatccga ttttaagata gatgttaaaa aataacaggg 83580 aggaccgggt gcggtggctc agacctgtaa acccagcact ttgggaggcc gaggtggggg 83640 gattatgagg tcagcagttc gagaccagcc tggccaatat ggtaaaaccc tgtctctact 83700 aaatatacaa aaattaactg ggcatggtgg cgtgcgcctg tagtcttagc agctcaggag 83760 gctgaggcag gagagtcgct tgaacccggg aggcggaggt ggcagtgagc cgagatcaag 83820 ccactgcact cgagcctggg tgacagagtg agactccatc tcaaaaaaaa aaaaaaaaag 83880 acacattatt tcattttaat aatgttagtc aatttttttt gttgtcgatg agttgcgttt 83940 tgttcattaa gaatcagctg taacatttgt tgggacttgg tagaagataa ctgctaggtg 84000 gttgtagctg ccaggctttt aatgagagga gcttagttta gcgaaaataa aagaaaaaca 84060 aagattaata tttggaataa actgtaaact cagcttctga gtccagagat cagccagtca 84120 agattgttta gacttgagct tatctttaga tggtgaagtt aggaaggtag tgacagtcta 84180 atgagttttc ctagtttaca gtttgtatgt ctttggtgat tacatccagt gttctggtga 84240 acttcctgag gggcccaccc agcaacagac acaaaggtga tttatttgaa actgtaggaa 84300 cgaaaaagta atatattttc atcacccatt acaaggttaa cgagtgagac tcctataaca 84360 aaagacatat taataagaaa aaataatatc aaatgtagtt actaaaagta ttatgtgaca 84420 tgggagcttt tagaaatgaa gatcaaaaga accagggaga atcctgggtt tttttgtttt 84480 tgtttttgtt tttaattgag acaaggtctg gctttgtcac cctggctgga gttcagtgac 84540 acgatcccag gtcacttcaa cctccacctc catgggctca agccatattc cacctcagcc 84600 tcccgagtag ctgggactac aggtgggtgc cactgcacct ggctaatttt tgttttgttt 84660 tgtttttgta gagatggggt tttgccttgt tgcccaggct ggtcttgagc tcccaagctc 84720 aactgattca cccaccttga cctcccaaag tgctgggatt acagacatga gccaccgtac 84780 atggctggaa aaatctattt ttacagagag ctatgcaaat gtgtgattgg aaaacaaatg 84840 ggtatgacct agtggcaata atctgaggag aaattagcca gatctgttca gattcttctt 84900 ggtctctgcg tatagaaaag gactgctcct gagtgaggaa tttatgacct actttccggg 84960 gaggtaggtc agagaattct tttgtgaccc acttcagggg gaagaggtca aagactgtgc 85020 ttcctgcatc tattatctca atttctgagg tgccatattt gggggcatta tttacagaga 85080 ctcaaggggg tgtaagtgcc tattatcaga ggtcattctt acggaggcta ttaacgaaat 85140 tttaggtgaa tggctgagca gacatctaga agttgtcatc cagtctattt ctaattaggt 85200 tttttctttt ctgacgcagg tagttgattt tgcaggatct gctgtccctt aggagaagag 85260 ggccctaaag ttcaagtgat tgtgggactg gaggagataa aaggctggca ggggagggca 85320 gagggaggga ggatgaagca gttaggggct tgaaggggga aatatcaaag gaggcaagag 85380 aactgaaggg taaaataatg ccaaaaaaga ggtggacaga gttggcaaag catatcgtaa 85440 gcagggattt gagaagaggg gattcagatg acagagaaca tcccaaggga gaagcagaat 85500 ccaatataga gaatggattg gtcttaaata gagctgggag taaaagattc gcagcccagg 85560 aagtcaggga ataataccta cggaggaagg acttccaggc caagtatcca gggaataatc 85620 cccactgcta tggttctaat gatggtgccc tctcaaaaat tcgtgttgag gccgggcatg 85680 gtggcttatg cctgtaatcc cagcactttg ggaggccgag gcaggcggat cacaaggtca 85740 ggagatcgag accatcctga ctaacatggt gaaaccccgt ctctactaaa aatatagaaa 85800 aattagccag gcgtggtggc ggtcgcctgt agtcccagct actcgggagg ctgaggcagg 85860 agaatggcat gaacccagga ggcagagctt gcagtgagcc gagatcgtgc cactgcactc 85920 cagcctgggt gacagagcga gactccatct caaaaaaaag aaaaaaatca tgttgaaatg 85980 taatcttcag tgaaatagta tgttgcccag gctggtctta aactcctggg ctcaagtgat 86040 cctcccacct cggcctccca aaatgctggc actataggca taagccacca cgcctggcca 86100 agacactacc ttgaaagcac agagtaggcc aggcgcggtg gctcacactt gtaatcccag 86160 cactttggga ggccaaggta ggcagatcat gaggtcagga attcgagacc agcctgtcca 86220 acacagtgaa accctatctc tactaaaaat acaaaaatta gctgggcatg gtggtgggca 86280 cctgtaatgc cagctactcg gggggctgag gcaggagaat cacttgaacc cgggaggtgg 86340 aggttgtggt gagccaagat tgcaccactg ccctccagcc tgggcaacag agctagactc 86400 catctcaaaa aaaaaaaaaa aaaaaaaaaa aagaataaga aagaaagaaa gcacagagca 86460 gcccttacta gacacaaatt atgccagtga cttgatggcg taattggact tcctgactcc 86520 agaactgtga gaaacaaatt tctgttcttt atagatttcc taggctcagt tattatgctt 86580 agcggcacaa ctgactaaga tagaaattgg tactgagaag tggcagtgtt gcaataacaa 86640 atacctaaaa atgtagaggc tgctttggaa ctgagtaatg ggtagaggct ggaagagttt 86700 ggaagtgcat gctagaagaa ggctagtttg ccatgcatta aggcgattct gacgaggctt 86760 cagaagatga aaagccatag agaaagcctc cgtctttgag attatctagg tggttgtgaa 86820 cagaatgtta gaaagaatat ggacagtaaa ggacattctg atgaagtctt agatggaaat 86880 gagggatatc ttattggaaa ctggaggaaa agccatcctt gttacaaagt ggcagaggat 86940 ttgttcctgg aaagaacaga acaaggtctg ggaaagaagg gagtttattt ctgcagctgg 87000 ttacagggag aaggccggag taactcacca taccaactca aagttacaag tttttttcta 87060 gtgcttatat acattttaag ctcccatgct aggagtggaa ttgcacctcc aagcaggagt 87120 gtttccttca atctatatct aaactttaac taggacctag ggtctggaaa tctttctcta 87180 gagtcttgga aagcttttta atcttttttt ctttttcttt ttttttgctg tccataagtt 87240 tattgtctgt atctgaaaaa tcatcataga aaattgtttg gtttagctct cagcagcctg 87300 cttctgagct ctgaggaagc ttgcattctt ttgagctacc caatccttct tctgagcaag 87360 ggacattttg ggatggttcc acctcttctt tttaacttct ttcttgggct tattttcata 87420 gactggattc tctcgtatag cagcatgagc ttccttatac atttcctcca tcatgtctgg 87480 agttaccctg ttctttatgt attgagagaa ctgtttcttg taagcatttt catcttcttc 87540 cattaagtag cacatgtaat cggcaacatt ctggcccatg atgtgcttcc ggtgtacttc 87600 tgcattaaat tccttgcttt cagaaccata accagggaat tgtttggtac tgtgagggat 87660 agacaagcct ccatccacag ctcccttcag ggcaccaaaa actttattgc cagtggtagt 87720 tctggcaagg cctgcatcca aatagcaggt aaaggcactt ggctgaccat caatgctttc 87780 cacaatgtat tcatcgccag tcacctccac ttggccttca tagatcttgt ccatgccaaa 87840 cctactgaga agcctgcggg ccagcggcag gccagtacaa tatgctgcag cataatttgt 87900 cgggccaacc ttcacaccat attttggcag ttcgtgtgca tatgctgtgc agactatcat 87960 atccccctct atatgggcat aagcaatctg acaaatgata tctctgtttg ttacacgaac 88020 tatcatcctg tatttgagtg tgttgtattt atttttatcc tgtatcacca agcgtttccg 88080 agtatcgtaa tcagttttac cctctcatca tcgtcttcta aatttcactt ggtatctctt 88140 aaagtaggcc ttattcttaa caactttaac aaaccccatc ctgcagaaca gagacccgcg 88200 tccacagctc aacagagacc agcaggcaca gcggcgctgg ggcagggaga aggggaaagc 88260 tttttaatct tcagtgggta cctggaacaa ggtatctgtg taaaatgctt ttattattca 88320 accagacttt aggctaagaa agcccatttt aatgggttta ttttaatatt ccagccctca 88380 tgctcagtca cctgtttctc cagttcttta atgtttaact tatacattca ttagaattat 88440 aatagagggt cagtggaaac tgactgttct ggttgctaat gggagcctgc cctgccacaa 88500 acttggtgga agtatttctg tgtcttaata gttttttgga gggtagaatg taagagcgat 88560 gaactaggac atttggcaga agaaatctct aagccaagtt ttcagggtac tgcatagctt 88620 ctcttaactg cttatagtaa actgtgagaa gagaaaagat aggacttcta atcaaaaggg 88680 aagcagatta gctgggcatg gtggcacaca cctgtagtcc cagctactct gcaggctgag 88740 gtaggagggt tgcttcagca caggaggtcg aggcggcagt gagctatgat cgtaccacag 88800 tctgggcaac agagtgagat cccatctcaa aaaaaaatgc taattattat tattattatc 88860 attgagatgg agtcttgctc tgtcgcccag gcaggagtgc aatggtgcga tctcggctca 88920 ctgcaacctc tgcctcctcc cgggttcaag tgattctcct gactcagcct cctgagcagc 88980 tgggattaca ggcgcccgcc accacacccg gctaattttt gtatttttag tagagatggg 89040 gtttcatcat attggccagg ctggtctcga actcctgact tcgtgttcca cccacctcag 89100 cctcccaaag tgctggaact acaggcgtga ggcacctcac ctggccaaag actattatta 89160 tcattatttt atccaaaatg tgtttattga gatggtttcc cactcatctt gattcagggt 89220 gcttttagtg ctgctttctc ctgaaggacc atccttccat aagccttgct tttcctcctg 89280 taggctggca gaggaaagtg cagcagccaa cacccaaaac cactgttggc acatggctaa 89340 agaccgtggt gattttatag catcctgggc atttcacatc catgaagtag gaattggggc 89400 tctgcaccag gtgtttcttc ttgtgtttcc tcttctcctc ttctggagag ggatgaagga 89460 gatcctttgc aagaagcatg ttcttgtggg taggtcgtca gtgctggaaa gggccaaaga 89520 aaattatttt taaagggaag ttgaacataa agatttggaa aattaacagc ctggccttgt 89580 aaagaatttt ttaaataagt tcaggagaca aaaccaactg tgtggccaac tgaccgtttc 89640 ataaggagat tagtatgact agaatgccag atgctattca ttaagacaat gggagaatga 89700 ccctgaagac atttcagaga gcactgagaa tgccacaacc atcacaggcc caaagtgcca 89760 ggtccttgag ggaataacaa ttttaaggaa ggagcccagg attccagtgc aacccaagat 89820 gcctgtggga acttggggct cactgactat gctgcctcat gtatctgctc cctgaagtca 89880 agcaaagctt ccccatctgt ggttcaggtg ggcccaggta cagctcagat cactcctcca 89940 gaaaacacaa gtagtaaaac atggggcagc atgcatgtgg tgctaactgc aggcatgcta 90000 aatccacagc tgtgaaggca tggctttctc cacctaattt ccaaggaagc cttgaagaat 90060 gcctcagggc ccaatcagag aactgctgta ggggcagggc tgccatagaa agttcccact 90120 agggcaatgt ccagcagaac tattgggttg gggccaccac agagtgccct cactagggca 90180 atactcagtg gagccatagg gacagggcca cccctgagtt cctagaccca gacctgtaga 90240 tccggtagtg cgtattccaa cctgtaatag acatagacac ctgactacaa cctgtagaac 90300 tgtggcatgg gctgactcca gcagtcatgg cagcagggtc ccctgggggc ttgggaacct 90360 aagcactacc ccagtgtctc tgtaaggtga gaggtagaat caaaaaagct gactctcaca 90420 cctcaagatt gaattttgtt ggccttgttg ggttttgaag ttatgtggga catgttaccc 90480 ctatcttctt gcctatttcc tccaccaacc ttttgttttt gccatggggt cgagctatgt 90540 cacccaggct ggtctcaaat tcctgggctc aagagatcct cctgtctcag cctcctgaat 90600 agctaagact gcaggcacca tgcctggctt atttctgact tttataaagg gaatgtttat 90660 cctgtgcctg tccaaccatt gtattttgga aacacataat ctgtttgact tcacaggttc 90720 acagctggag agccattgtc tcgggattaa ttgtaccttg agcatcacct atatctgatt 90780 tagatgatat ttacatgcga ctttcgactt acacttgaaa gttgatgctg gaatgagtta 90840 agacattttg gagttactaa gatggaatgg acatattctt gtgggtgaga acgacatgaa 90900 ttctcatgtc atggcaaggg tggagtgcta tggtttgaat aatggtgtcc cttctaaaat 90960 tagtgtggaa atttaatgcc caatgcaaca gtattaagag gtttggcaat tgcgtggtga 91020 ctaagccatg agggctctgc tctaatgcat gagattaaca tctctataaa agtgtattaa 91080 tttaaaggga gtactttctt gcccttctgc cccattcacc atgtgaggac atagtcatgg 91140 ctcctccaca ggatgcagca acaagacatc atcttggaaa cagacagcag ccccgtttag 91200 acctccttct gctgctttga tcttggacct ctcatcctcc agaaacacga caaataagtt 91260 tatgttcttt ataagttact cattatcagg tatttattta tttatttttt tgagacagag 91320 tctcgctttg tcgcccaggc tggagtacag tggtgtgatc tcagctcact gcaacctccg 91380 cctcctgggt tcaagtgatt ctcctgcctc agcctcctga gtagctggga ttacaggcat 91440 gcactaccac acctggctaa ctttggtatt ttcagtagag acagggtttc accatgtttg 91500 ccagtctgat ctcgaacccc tgaccttagg tgatctggcc ccatctgcct cccaaagtgc 91560 tgggattaca gacgtgagcc actgtgcgtg gccaatatca ggtatttcta atagcagtac 91620 aacggactaa gatactcagg aaaacagagc caggaggaaa aatattctat ctcagggagt 91680 taaggaatca tgcccactca agaaagagta taagggctgg gcatagtggc tcacgcctgt 91740 aatctcagca ctttgggacg acaaggtggg cagatcactt gaggtcagga gtttgagacc 91800 agcctggcca acatggtgaa agaccacctc tactaaaaat acaaaaatta gccaggcgtg 91860 gtggcacatg cctgtaatcc cagctacttg acaggctaag gctggagaat cgcttaaacc 91920 tggtgggagg cagaggctac agtgagccaa gatcacgcca ctgcacttca gcctgggtga 91980 catagtgaga ctccgtctca aaaaaacaaa acaaaacaaa acaaaaaaaa caaagaaaaa 92040 gagtgtaggg gaaaaataac actcagttta ttttttagtc caaacagacc cctttaacaa 92100 aataaagatt aacaagagaa aagcaaacaa gtttattaat gtgtgtattt catctacaca 92160 tggaaaatac ccagagaatg aatagttatc aaagaagtgc tttgaattcc agcatatata 92220 gcatcttcag cagagaaccg tacattttta gagaagtgaa aagataaaga aaaaggagat 92280 tgtgtccgta ggggtgacaa cttacggaaa ggcaaataaa ttgcagataa attcagttac 92340 taagcatgtt gctataaatt cctttggtat catttccagg ctgaccaggg tctaaagttt 92400 tcttcagtgg ttagcctttg ttctccctgg taaaagcgtg agtgtggaga gtggggaggg 92460 agagggtacc ttttgtcttc gcaactctat atcttgcttt tcggccagta aaggaagaac 92520 aaaaaacttc cctgcatctg cttcttctta attgtcttca gctcaacaat gcttccagtt 92580 ttagggtggc atattctggc ctcccacaag agccaggaag aacagatgtg cagcccaacg 92640 gtgaggaaat aattttcacc ctacaaagag ccaggaaaaa gaccttccat tccaggaagt 92700 acctttcaaa agatacctgg gagtctaatc cagcttcaaa ctatactctg aattcttaag 92760 aatcaaggcc aggtgtggtg gcttatgcct gtaatcccag cattttggga ggctgaggca 92820 aggggatcga tcacttgagc ccagggtttg agaccagtct gggcaacata gcgggatagt 92880 gagatcctct ccacacacaa aaattaaaaa taaaaataaa taaaaaaaat taaaacctat 92940 ccttacaagc ttcagtggac acttgtccag agcaatcaat ggctccagag tctaattcac 93000 cagtggatcc ccaatcaact tattaggaat aaagacaagg tttcaaaggt gcaccctgag 93060 gtcctgggtg agaggtccag gggaccaaaa atgaataact gaaaaaatta tatattcagt 93120 gatacttatt aaagcatggt aaagaaaact ttattcagga ccattgtgat agatacaggg 93180 accaatgcaa tgggattttg caatggaata gagagattgc tctgaactcc aaatagatca 93240 tgggaaaaag ggacgttata accaagaagc agggttgggg tgtagtgggt gaaggaatgg 93300 aaaattacta aaaggaaaca tcagggataa gggggattct ggctaaactg acacctaaca 93360 agattcttgt taaagatggg ccagagtggt catgtatcac ttggaagatg gtggaagatg 93420 aacctgatca gatatcaagg gtgatcagat atcaaggaga agagggttct tttttatatt 93480 tatttattta tttatttttg agacagagtc tcgctctgtc atccaggctg gagtgtagtg 93540 gcgtgatctc ggctcactgt aacctccgcc tcctgggttc aagtgattct cctgcctcag 93600 cctcctgagt agctgggatt acaggcgtgc accaccatac ccggctaatt tttgtatttt 93660 tagtagagat agggtttcac catgttggtc aggctggtct caaactcctg acatcgtgat 93720 ctgcccgctt cggccaccca aggtgctggg attatggggg tgagccacct tgcccggccg 93780 agaagagagt tcttgataaa cagacttcct tgttaaaact agattttata atgaggtcca 93840 cagatgggtg gaggagaagc ctgagtaaat tttggttaag cagagaaact ttgtcatccc 93900 tcctgtatgc attatgctcc cttttctcca gtggagctct cttcaacctt gatgttattg 93960 tccaatcagt ttgttttccc agtgttgatg ttctgatttc atcctacaaa aatatagcat 94020 aaacttgtat ttgttgcatt ctacaacata agcctgacaa tataacaaac tgttcccaaa 94080 gttataaatt cctcgtcttt ttatttgtaa tttgactttt aaaaatctat gtaattatag 94140 aagaatgttg ctactataaa aattttaagg ggtggcaggg aataattcca aaattataaa 94200 actccttgtg acaaatttag gaatgatatt cagctagttc tatagttttt tattccttga 94260 ataatcagcg atatacatct gattatatac acacattgtg gttttttttt ggccaggttg 94320 actttttttt tttttttttt tttgagatgg agtctcactc tgccacccag gctggagtgc 94380 aatggcacaa tctcggctca ctgtaacctc tgcctcccgg attcaagtga ttctcctgcc 94440 tcagcctccc attacaggca cccgccacca agcctggcta acttttgtat ttttagtaga 94500 taatggggtt tcactacgtg ggccgggcta gtcttgaact cctgacctcg tgatccaccc 94560 acctcggcct cccaaagtgc tgggattaca ggcgtgagcc accgcgccca gccttggttg 94620 acttattctt ttaaggagca atgtgggtta atgtttcaaa gtgaaaaaat ttaaaaactt 94680 aggggaaagt ggggggagag agagacaaag acagagacag aaagagagac agagtgagag 94740 atggagagag atcagatagg tacataagct tagtgactca gcctgtagtc ccagttactt 94800 aggaggctaa ggcaggagga ttgcttgagc ccagaaactc aagttttcag tgagcagtga 94860 tctgcaacac tgcactccag cccatgtgat agaaccagat cgtctctaga agaaaaaaaa 94920 agaagaaaaa aatacatata catacataca ttggtgtttg tttctacata tgcttcatag 94980 tatatgtgta catggattat aggtagatca tataatggta acagtattaa attaggtgtc 95040 agcatttgtt gaggaagtag tacgctcgtg tttgaaattt taattaagaa ttgtgtacgg 95100 agttggttcc ttccggtggg tttgtgggtt tgtggtctca ctgacttcaa gaatgaagcc 95160 acaagccttc tgaaccttcg tggtgagtgt tacaactctt aaaggtggca cagacccaag 95220 gagtgagccg cagcaagatt tattgtgaag atcgaaagaa caaaatttcc acagcataga 95280 agcagactga gcaggttgcc actggtggct ggggtggagt ggccagcttt tattccttat 95340 ttgtccccac ccatatcctg ctgattggtc cattttacag agtgctgact ggtccatttt 95400 acagggtgct gattggtcca ttttacaaac ctctagctac agagcatcga ttggtgcatt 95460 tttacagagc actgattggt gcattttaca aacctgttgt aagacagaaa agttctccaa 95520 ggccccacct gacctacgaa gtccaggtgg cttcatctct cagaatcagc ttttaaaggc 95580 cataaatttc caggtaagta ggaatagaag aaatgaacat ttcctttgag atctatgatg 95640 tcatattttt ttctccatca acgatttagt tccttctgga tcaaatactt tttaaatgga 95700 tgtatgtttt atagtagatg ttatgttgtc ttaattattt taaaactcct attcctggac 95760 tctcctgaag aggagaattt agtaatttcg aagtattttt tgaggctagg gaagaaaaac 95820 caagattact gcataaggtt tcaggggatg ttccatgcct gccacctggt gaaaatgagg 95880 gagctttcct cctacctgcc accattacac ctgcctgcag gtaataacgc catcatttca 95940 acgcggcctg gggtattctg ggaaggtgac gtgtgggggc gcagtgaccg ctagcagggg 96000 ccaaacccgc cctggtctgc gctgcagtgc gcagtgagga tgttggtgct gctcttcagg 96060 gttttctttc cgcagccacg ggaagcccgt gttccatatt tgtttttcat gttctctcgt 96120 ttttatgttg tggatttagt tttttaaaaa ccataaatgt tcctctacag tcttaacaat 96180 gtaccctgta aaataagatt ttaaaagagc caacttccct attaatctta tacttttttc 96240 ttttcgttct ggctttaaca aatgtgacct aaagagagct cttgatttta tgtagaacaa 96300 tacaagaata gttttacatt aatcttatgg ttagaaaaat catttatggg caaatttgtt 96360 cccatgcctt acttttaaaa tattgtgttg tctttaattt tcaaaatact ttaaatattt 96420 ttcagtaagt ttgagggtag aatttatttt aatgagactc ctcttataaa aagtacgtat 96480 ctgtatgtgc atatgtgtat actgaatttg ctttgctttt gattctatca ttctgtcact 96540 tttctatcaa aatatctcta atggacagag gccagagaca aggactttta cagcaaattt 96600 gccacagtac cacacatttt atcttaaaag atggtatgga ttttgcataa catatatatg 96660 caaacatata tatatataac ataatatata tgtgtatata tatataacat tatatatatg 96720 tgtatatata taacataata tatatgtgta tatatataac ataatatata tgtgtatata 96780 taacataata tatatgtgta tatatataac ataatatata tgtgtatata tataacataa 96840 tatatatgtg tgtatatata acataatata tatatgtgta tatataacat aatatatatg 96900 tgtgtatata taacataata tatatgtata tatataacat aatatatatg tatatatata 96960 acataatata tatgtgtgta tatataacat aatatatatg tgtgcatata tataacataa 97020 tatatatgtg tgcatatata taacataata tatatgtgtg catatatata acataatata 97080 tatgtgtgca tatatataac ataatatata tgtgtgcata tatatataac ataatatata 97140 tgtgtgcata tatatatata acaatatata tatgtgcgca tatatataat atatatatgc 97200 gcacatatat ataacaatat atatatgtgc atatatatat aacataatat atatatgtgc 97260 acatatatat aacataatat atatatgcgc acatatatat aacataatat atatgcgcgc 97320 atatatatat aacataatat atatgtgcgc atatatatat aacataatat atatgtgcgc 97380 atatatatat aacataatat atatgtgcgc atatatatat aacataatat atatgtgcgc 97440 atatatatat aacatagccg tttggtttat tttatgtgtg tgcgttaaaa agttattcaa 97500 ttgctgggcg tggtggctca cgcctgtaat cccagcactt tgggaggccg aggcgggcgg 97560 atcacgaggt caggagatta agaccatcct ggctaacacg gtgaaacccc gtctctacta 97620 aaaatacaca aaaaattagc cgggcgtcgt ggcgggcacc tgtagtccca gctactcggg 97680 aggctgaggc aggagaatgg cgtgaacccg ggaggcggag cttggagtga gccgagatag 97740 cgccactgca ttccagcctg ggcgacagag cgagactctg tctcaaaaaa aaaaaaaaaa 97800 tattcaatta tgcttgttaa agcaaggtaa gggtcaccat ggtgataggt acagggacct 97860 ctgcagatag agattgggct aactccaaac agcgtaggca agcggaaatt tataaccaaa 97920 gagcaggctg ggaggtctgt gaatggaaaa ttaccaatga gaaacctcaa aggttagggg 97980 gattctggct aaaccagcct aacaggattt ttgctgaaga caggccaggg tgatcaaaca 98040 tcacttgggg gatggtgcag gatgatgaac ctggtaagat attaagggtg atcagatatc 98100 aaaggtaagg aagttcttgc taaagctgga tttgacaagg aagtgcacag actggagaag 98160 gttcaggtgc ctgactaatg tttgatcaag caaagaatct ttgtcagtgt acagaacgct 98220 atgtttttat aaaatgttcc tctgccccat ttgtatctcc ccttttcatg gaacacaaag 98280 cacgttttgc ataacttcta gatacatgta cttctatttt gaatgacctg atatatcttt 98340 tttctttaca attctcaacc tcagcatatg taagtggaac tcagaaggca acattccctg 98400 aacatactct tccaccagaa tctcctctac agatttttgc tgcccctttt accagtggct 98460 gaatctactt tctcttatgt aagtagaaat tttatatatc tccagcctct tcctccttac 98520 cttccacttg catgcacatc ctgtctagtc tgtgacctcc tctgttataa atgcttgtaa 98580 accttttttt ctgaatcaga aacgtgttgt gttgctcaag ccgtgttcat tttaattacg 98640 atttaactgc ataatttaat tatttcccca ttttttggat acagtgtttg cttttctccg 98700 gttactttgt tctagtatat ccctctggca agagcagtca tttccccact tgagtgtgca 98760 ttagtatcac ctgggggctt gttaaacaca gcgtgcaagc tccatcccag ggtttctaat 98820 tctcagggtt tggtttgcgg cagaagaatc tgcatttcga acaagtgcca ggactggtct 98880 gaggaacaca cgttgagaga ggtgggattc gggttcacta acctgggtta gagaaaatta 98940 cagtaatgtg ccaaatctga ggagggagca gagctgaagc ccagtttcaa tatgtgaatg 99000 agtgctttat acactcaaac cccctcaagg gctggggagt aagggagaac gtgggcgggc 99060 agcgggcgtg tatagaggca taaactcaat cccagaccta tggattcaga atcacatgtt 99120 aacaattctt ccagtgtttt gtatgtttat tatagtttga gaatgactgg accaaattgc 99180 ctccaaaatc ttaagtccca gcagtgaagc gaagctcaga catcatttgc atagctattg 99240 ctttgtgtct gtgttttagg tcagctgctg ttaaaggttt gtttcggaga gttacccagg 99300 tgtagtaccc ttccaagtag ataatgattg aaagagtatg tgctggaggt gtatgatatt 99360 ttccatccac ttcagcccat ttttctgatg ggtcagtgac agtccatgat ttgtctggtg 99420 taatacaaat tctggaagtg gcatatatcc aaggacagcc ataatattcc acttggccaa 99480 ggctcttctg acaggctcat gttcatgcag gatcagatct gacccagaat caacagaact 99540 gaagctgcaa attcagcttt gtgaaggctt cagatgtagc catggttaaa gaagattgac 99600 attaagcagg tgagcagagt ttgcttgagg ttcacccagg gaattcgtga ggatgcaggt 99660 gcgttttttt atggcctgaa aagcccagtt tttgaggagt tacagtccct ctcagaaact 99720 gttcctgcag agtagccctg gaaacatgtt tgtctgcatt caagaaagat cttccttctg 99780 ttcatataaa ggaagccaaa cttatttccc aggtaaggga gtggaagcaa ctgtgatacg 99840 gaatcctaag gcatgggggt tagttgtaat ccaggcaata tgtagggtca ggttctccaa 99900 gtcctcctgt ggttaaaggg ctccacccta ggaaagtgag ccacccaggg cttggtaaat 99960 gaccttatga tcagcccttg gcctgttaac atgtcgtaac tgaggcacag gactgggttc 100020 ttggtttgaa tttgctagtc agatggccat tgcagaaagg gaagagagca cagtccttca 100080 ggccaactca cttggcctat tgaaactggc ttttctgagc acagtctagt attgttgcga 100140 attaaataca gcagaggatg taagttacca gtattagtca ctatcagttg agtacttatt 100200 ctgtatcagc cactgttcct cttttccatt tccacctgtt atatgttagt gacgataaaa 100260 atgccataca gaccgggcac ggtggctcac gcctgtaatc ccagcacttt gggaggccaa 100320 ggcaagtgga ccacctgagg tcaggagttt gagaccagcc tggccaacat ggtgaaacct 100380 ccgtctctac taaaaaaaaa aaaaaaaaaa aaaaaaatta gccgggcacc gtggcgggct 100440 cctgtaatcc cagctactag ggagactaag gcaggagaat cgcttgaacc tgggaggcgg 100500 aggttgcagt gagccaagat cgtgccattg cactctagca tgggcgacaa aagcaaaact 100560 ccgtctcaaa aaagagaaaa gaaaaagcca tacaaaaagg ctaagagcct tgttcaacct 100620 cacacatgaa agtggcaggg ctggggtatt aattcaggca ttcacaatcc agatcctcta 100680 cacatttcac tgacatgaaa cccagaaatt tcaggtctac taccttgaac ccagaactat 100740 ttttctcaaa cttgttttct tgtgagctat atatagggaa aaattgcata caatacagta 100800 ctgctttaca aatatatcat ctaataccca agtcaagaaa gacatgatcc tgagctccct 100860 caaaactcgt gggtatccct tctgaatctt gaccttttat tctgactgag atgaatcctc 100920 catgctgctc tttgtaattt tattcctcgt gattacatac ttaagctaca ggaatacatc 100980 ttacgtagtt ttgtttattc ttaactgtat gtattttttt gtcttttcca cttgatattg 101040 cattttctgt atttatccat gttgtgtgta attccagctt cttaattttt attgatggtg 101100 ttctctcatt atatataata tatacagcat gtagcatgta tctttctcac tgtgtatgta 101160 tacagagtgt atgcatatca ctataggtat acagacatat cattatccta gtatttccat 101220 atctatgcca cagtaggcag atcctttttt tttttttttt tttttttttt gggaagacag 101280 agtctcgctc tattgctcaa gctggatgga gtgcagtggc gcaatctcag ctcactgcaa 101340 cctccgcctt ctgcattgaa gcgattctcc tgcctcagac ccccatgtaa ctgggactac 101400 aggcacctgc caccacaccc agctaatttt tgtattttta gcagagatgg ggttttacca 101460 tgttgtccag gctggtctcg aactcctgac ctcgggtgat ctgcctgcct cagcctccca 101520 aagtgctggg attacaggtg tgagacacca tgcgcggctg cagatccctt ctatacctga 101580 tgattgtttg ggttgtgtct agtctgcagt tatcaccaac actgcaatcg taatcactga 101640 agtatgtgta tcctgattta tataggtaca catctctcaa ggatctgtaa ctggtagtgg 101700 aattcatgga tcttcaattc aaatgttgct catggcagtg ttaattataa caaccacttt 101760 ggtaaactac ctgctattac ctacaaaacc atgtgtacct tacacacgca ccatccattc 101820 tactgtgtgg agtaggccac ggaaaagtac atgcacagtt gatgaaaaga catgtattta 101880 aatgtttata gcagcattat ttgtaatagc caaaactgga aataaagcag agtgggtaag 101940 taaatggtgg tataggaatt caatggaatt caactataaa taaaaaataa tgaactgtat 102000 ctacatgtaa aaaccttgat gaattttata aacacaaagt tgagcaaaat aatctaggca 102060 aaaacatact tgtctgagcc catctctgta acattcagaa gtcagtatga caagtcagga 102120 tggtggttac ctgtgacagg agagaggctg ttttgggaag ggctcacttg ggtcttctca 102180 gttgctggag ttcactgtga taaatttagg atttgtttct ttttagtgcc gtgtatgtgt 102240 gtgtgtgtgt gtgtgtgtgt gtgtgtgtat ataaacattt tttttttttt tttttttttt 102300 ttgagatgga gtctcactct gtcacccagg ctggatgcct ggctttttgt agtttagtag 102360 aaatgaggtt tcagcatgta gctctggctg atctcaagct cctgaactca ggagtctttc 102420 ctcctgtaca ggagggaaga cctttcctct actttctgag aattcaataa ttgagtcctt 102480 gaaagaaatt gacagtagtc agattaatgg gagaaaaggt atacaaatta gatatggaca 102540 cagggacatc acatgaaaga aaagcgaata tcccagaacc cagtgagatt cagaagctta 102600 tgtaccctct tcttaggaca gagggtatag gtgattaggt aacttagggg agagtaaaca 102660 gtttggggga aagataaatg gactgtcaga agaacaggta acagccggtg acaaagtctg 102720 cgtgtgttat caaggtctac tctcctctcc tgtgatagga gccaatcttc cctggttagt 102780 gagtttcctg gggaggggat tcatgacaat taagttcctt ttagataatc tgtctttaga 102840 taaggaagct cagagaaaac ctctgcctgt atgagctgct ccccacataa cctcagttga 102900 aagtaatcag cacaccaaag catcatattt tggggtggag atcctcccgc ctcagtctct 102960 caagtagcta ggaccagagg catgcaccat catgcccggc tacttttttt ttttttattt 103020 cttgcagaga cagagtctca ccatgttgcc taggctggtc tccaattcct gacctcaagt 103080 gatcctccta tctctgtctc ccaaacagct gggattacag gcatgagtta ccatgcccag 103140 gctaggggtg gcatttcctg aactccttca gccctcttgg gaaatgtgca ggcaggaaga 103200 aagaaaagaa tacccttgtc cacagccagg tcttgttgag cttatgcttg gcagaataga 103260 accttacacc cagccacgtg aaaactggga tgataaatgt ctgcatgtct gacagaaggt 103320 ttggcctctg attcagctgt ggtgattttt ccatctactt aactccaaat tctattagct 103380 agtataaact ctctattgga ctatgaacac agtaagtaca caatcatatg attattttat 103440 ctattgactt aaatagaatt gtgtatgaag gctgtactga agttattcag ggttgagtca 103500 ggaaaagcta aatttcaacc tcttttaaga aaaatattga tgcctccaaa tccatagtat 103560 atatgttgct tactagctta taaagggccc ctggaagaaa ggacatttcc ggtgttttat 103620 gtcaatcata ggaaaataag ctataagctt ttttttaatt ctttgattct caaaagtagg 103680 attgtggcca ggcatggtgg ctcacacttg tacagcactt tgggaggctg agatgggaag 103740 atcgctcaag gccaggagtt cgagaccagc ctgggtaaca aagcaagacc ccatctctac 103800 aaaaagaaaa atgtatgatt gcgtccccct accactcccc aacacttccc tggctccaca 103860 ccccagttcc tctgctctca tttctgctgt gtcttactcc atgaagcttt caaaactgct 103920 tttatagagt cctccttttc ttttttataa atttattatt gttgttgttt aattaaaaga 103980 caggatctca ctctgttgtg cagttgtgcg atcactacag cctcaatctc caagcgatcc 104040 tcccatctca gcctccccag tggctgggac cataggtgca taccaccatg cccagctaat 104100 tttttttttt tttgagacag agtctcgcac tcttgcccag gctggagtgc agtggcgcga 104160 tctcggctca ctgcaagctc tgcctcccag gttcacgcca ttctctggcc tcagcctccc 104220 gagtagcggt agcgcccgca accacacccg gctaattttt tgaattttta gtagaaatgg 104280 agtttcactg tgttaggcag gatggtctcg atctcctgac cttgtgatcc gcccgcctcg 104340 gcctcccaaa gtgctgggat tacaggcctg agccaccgtg cccggcccac taatttttaa 104400 atctttttgt agagatggga tctaactatg ttaaccaatc tagtttcaaa ctcctggcat 104460 caagcagtcc ttctgtccaa agtgctgaga ttgcaggcat gagccactgt gccaggcccc 104520 tcattcttta aatagctact ttagattcta ttgtaaggat attttaataa ttttccaact 104580 tttattatat tgagtaggtg attccttttt aaattatata tgtaaatttt tatttatata 104640 tttgaataat atgtttacat agttaaaaat caaaatatac gaaaggcata cagtaagaag 104700 tcatctcttt ccacccgtaa tgacaatata tccccttttg cctggcacag atgcacacat 104760 aaattattgt cctgacatga ttatgaataa tcctgctttc tctcagaagt gtgctagttt 104820 gaatgataaa ttatgcagac attctgcttg tatccctgct tcttcaccat gctgttatat 104880 tccttccaat tcagaggcaa atgtgatatc attgcctatg tgtcttccag aggaatttta 104940 tttatatttt gtaagtacat acatggattc tggttttttt tttgcacttt ttaacaaata 105000 gatgtatcca tgctatttta ttttaaattt ttactttgaa acaaccttaa acttacagaa 105060 gttaaaagaa tattagtagc aggtgtgctg gctcacgggt ataatcccag caccgtggga 105120 ggctgagatg ggtggattgc ttgaggccag gagtttgaga ccagcctggg tagcataatg 105180 agacctcctc tctacagaaa aaaaaaatgt aaaagttagt tgggtgtggt gttgcatgcc 105240 tatcgtccca gccactcagg aggctgaggc aggaggatcg cttgggtaca ggagttagag 105300 gctgcactag accatgatca caccactgca ctccagcctg ggtgacagag tgagaccctg 105360 ttgcttaaaa gaatatttta aaaaaaacct accctttatc cagattcaca aatactaata 105420 ttttttcaca ttatttaatc aatttttctc cttccctccc tctttcattt ctcccccttt 105480 tctttttttt tggagacatg atcttggttt gtcacccagg ctggggtgca atggcataat 105540 catagctcaa tggcatttca aactcctggg ttcaaagaaa cctcctgcct gagcctccag 105600 aatagctggg actacagtca tatgctaccg tacctggcta atttttaaaa ttttttatag 105660 agacaggatc ttgccatgtt gcctaggctg gtctcaaact cctaggctca agtgatcctc 105720 ccaccttgac atcccaaagt gttttgatta caggcatgag ccaccaagcc tggcctcctt 105780 tccctctttt ttttctccct ctgtttccca ctgcttataa agtttttaaa tttttttttt 105840 tttttttttt tttttttttt tttttttttt ttacttttga ccactttgag agaaggttgc 105900 agacatcatg tccctaatgc atttcctgag aaccgggata tacgtttgga taatcatagt 105960 aaagatatta attcaggaaa tataacattt atacaattat tttatctaat ctacaggcca 106020 taacccagtt tcttcatttg ccccaataat gttttttata gctttttcat gttaaatatc 106080 ttgtttggca ctaagtatct tatcagtctg ccataatgtt taatatcttt cctctgaaat 106140 ggttcctctg cctgcctttg cctttcatgt gtttgtgact tttgaagcat gcatgctagg 106200 tatgttacgg aatgtcctca gcttgagtcc atctgaagtg ttcttaagac tggattctac 106260 tgatgctgtt ttggttggca caacacggtg tttactattg tggtcgtcaa aatgatgttt 106320 tatggctaaa ccattctttc aacatttaat catcaaggaa atataaatca aaaccacaat 106380 gagatatcat ctcatcccag ttagaatttg ctgttatcac aaagacataa aaataaatgc 106440 tgatgaggat gcagatgaca gggaactctc ctatactttt ggtgggaatg tgaattagta 106500 tagtcattat ggaaaacagt atgcagagtc ctcaaaaaac tacaaatgga actaccctgt 106560 gaaccagcaa ttccactact gagtatttat ccaaagttaa atcagtgtat tgaagagaga 106620 gctgcactct tgtgttcatt gcagcattat tcacgatagc caagatatgg aatccaccga 106680 agtgttcatc aacagacaaa tggattaaaa aaatgtggtg catatacaca atggaatact 106740 atttagccat aaaaaaagaa tgagatctgg acattcacag cagcatggat ggaactggag 106800 gacattatgt taaatgaaat aagccaggca cagaaatata aatagcttaa aaagttgacc 106860 tcatagaagt agagagtaga attgtgatta ataatcacaa ttataaataa tggtcagtat 106920 caaaaaaaat tgtcattcta cagtgctgca gaacattaga acttgttttc tctatctagc 106980 tgtaattttc cctcttttat tttttttgaa acagggtctt gccctgtcac ccaggcatgg 107040 cataagcacg gctcactgca gctcaaacaa tcctcctgcc tcagcttctg gagtagctac 107100 aggcacatgc catcatgcct agctattttt ttttaatttt ctataaaggt ggggtcttgc 107160 catgttgccc aggctagtct caaactcctg gcctaaaaca atcttcctgc cgtggtctcc 107220 caaagtgcta ggattacagg tgtgagccat cactcccagc tccaattttt agatactgac 107280 cccatttaga tacatgacct cagaacacat tccaagctca tgttgtatct ctcttgtccc 107340 cactattaaa tcagctgtgt tttttccaag gaatcctgat ttctattgtg gagaagcgta 107400 cttagaaacc aaggtcttgg tgctactggt atgttattgc ttttaggccc ttccagatat 107460 acgggatata aagatatagc tatatgtatg tgactatatg tattgtgtat atatgtatgt 107520 agctatatgt gtgtatgtgt atatatatct tcatgtattt atagtgatat tttccatccc 107580 aatctacacc gcagggtttt tccttgcctt cctatttgta gagcttcctt ccacattaag 107640 aaccctctct cccagtgagt gtcaccccat ttctgtttca tctctttccc tactctcccc 107700 cttgcctcct agggtcccct ttcctctcat cagttgccag acaagaggag catcatcata 107760 cacacatcat agatttaata ttaaactttt aaaattttca gataaatgta agcaggcttc 107820 tgcagtgaaa ggggccaggt ctaggaagat ggggaatact tgcaggcacc tgggaagctc 107880 agggaagctg caggtaccct gtcagttggg tgtcccctca tgagggtggc agactgtctc 107940 cttgagttct gggtggcaga aatggcccag ggccctgggc tgagacccag ccaactctct 108000 atggggctgc cacacgactt cctaaaaagg cataaacaca ttttcttcca agtggagtcc 108060 agcatatttt attttcctgt tgaatggtag acagcatgag agcagggtcc atgtgatgat 108120 ttttctgtca gtatcagttt ctgcaagagc aaaaattaca tatttttatt tttcaaataa 108180 aatcaattga gacagtaaca aatttgctca aagaatcaac ctgaacacat gtacatctat 108240 tatgtatcaa taaaaaaatg gccaggcacg gtggctcaca cctataatcc cagcactttg 108300 ggaggccaag gcgggtggat cacgaggtca ggagatcaag accctcctgg ctaacgcggt 108360 gaaaccctgt ctccaccaaa aatacaaaaa attctctggg cgtggtggca ggtgcctgta 108420 gtgacagggc gagcttgcag tgagccgaga ttgtgccact gcactccagc ctgggtgaca 108480 gagcgagact ccatctcaaa aataaataaa taaaaataat aaattttttt ctagataaaa 108540 aatataaaaa ttacaccaca gtccaaaaaa aaaaaaaaaa aaactgttca agactgatct 108600 ttcatagtga ttgggtctat gagtaaatgt taaatagatg atttattagg tttcttttta 108660 tttcaatgat gagatggaga aatatattat tttacatgag ggcaaaaaat attttatgca 108720 tagatatttt ttattttgcc tatgtcctta aattctcaga atatagatta ttgccttcag 108780 aaatctgtct aggttcacct ataccttatt agaactcagc tttgctggct gtggtacacc 108840 tgtaatccca gcactttggg agactgagaa gggaggatca cctgagctca ggaatttgag 108900 accggcctgg gaaacatagg gaaaccctgt ctctacaaaa atacaaaaaa aaaaaaaaaa 108960 aaagtctggg tgcagtggct cacgcctgta atcccagtaa atcccagtac tttgggaggc 109020 cgggccgggt ggatcccgag gtcaggagtt caagaccaga ctggccaaca tggtgaaacc 109080 ccgtctctac taaaaataaa aaattagcag ggcatggtgg tgagcatctg taagcccagc 109140 tactcgggag gctgaggcag gagaattgct tgaacctggg aggtggaggt tgcagcgagc 109200 caagattgtg ccactgtact ccagcttggg cgacaaagca agagtctgtc tcagaaaaaa 109260 aaaaaaaaaa ttagccaggc atggtggtgc acacctgtag tcccagctac tcaagaggct 109320 gaggtgggga gccctagtgg gtgcagtgag ccaagatcac accactgcac tccagcctgg 109380 gcgacagagt gagactctgt ctcaaaaaac aaaaaagtga gctttaataa attctataaa 109440 acttttttct agttgagagt acgttactac aagctaactt ttaaaaaagt catattattt 109500 gattactagg aactttgcaa ttagttttgc ttcttctggt ttttattttt gcctggcaca 109560 acatttcctt ccttggcccc tgtctgtatt aataatgctg ccaggatata ctgaatgatt 109620 ttattccagt tttttctacc ttaattatgt taaagaaaaa caaaagctgg gtattagtta 109680 tagtggtaag gacacatttt aatcactaat aactattgta atcgtgaaga aagtccagca 109740 tgaactgaac tcaactttgg tgtgtacaga ggtgactggg tattttaaag gaagaatgaa 109800 gctgggtgtc tactggacac tggaatgaag ctactgcaga ggctgaggca gaaggattgc 109860 ttgagccagg ggtttgagac cagcctgggc aatacatcaa gacctaggct gggcggggtg 109920 ccacacgctt gtaatcctac actttgggag gtggaggggc ggggggtgaa tggcttgagt 109980 tctggagttc gagaccagcc tgggcaacat cgtgaaacac tgtctctaca aaaatacaaa 110040 aattagcagg gaatggtggc acatggctgt agtcccagct actcaggggg ctgaggtggg 110100 agaatccctt gaacttgagg agacagaggt tgcagtgagc caagatctca ccactttact 110160 gtagcctggg tgacagagtg agaacctgtc tcaaaaaaaa aaaaaaaaaa aaaaaaaaaa 110220 aagactttgc ttcacccaca aagggaaaat cagggaatag gagggagttg agttgtgggg 110280 tagggtatgc tcagttgagt cagagaagta aaaatttacc aaaagtggtg gttccatgta 110340 aaacctacct gggattgcta actggtgctg tttgaagtta gactatgacc ctcgcacaga 110400 ggccaggaga caggggccct atcttctgct gttggctgga acaaagagta aattcatttg 110460 ggaggcttca cttttttcag gcaggctatt taagggggat acagtcaacc aggggatatg 110520 gccttgagat gctagaatct atgttagtat tttgttcaaa tatttatagg ccagggttaa 110580 gactgacttt gtttctttgt tttttgagat ggagttttgc tcttgttgcc caggctgaag 110640 tgcaatggtg cgatcttggc tcactgcacc ctccgcctcc tgggttcaag tgattctcct 110700 gcctcagcct cccgaggagc tggcattaca ggtgctcgcc accacgactg gccaattttt 110760 gtactttagt agaaacgggg tttcaccatg atgtccaggc tggtcttgaa ctcctgacct 110820 caggtgatcc gcctgcctca gcctcctgaa gtgctgggat tccaggcatg agccactgtg 110880 cccagcgtaa gacctagttg agaaggcagc tcagaggaac ctggctagag tttggtcaag 110940 aagactatct ctgtcaatca taatgtgtat tccaccaata agagtcattg agtctgtaaa 111000 tgtttttttt tttttccttt gagacagagt ttcactcttg ttgcccaggc tggagtgcaa 111060 tgacacaatc tcggctcact gcaaccttgg cctctcaggt tcaagtggtt ctcttgcctc 111120 agcctccaaa gtagctggga ttacaggcat gtgccgccac acccagctaa ttttgtattt 111180 ttagtagaga tggggtttca cgatgttggt taggctggtc tggaactcct gacctcaggt 111240 gacccacctg ccgcagcctc ccaaagtgct gggattacag gcgtgagccc ccatgcctgg 111300 ccaagtctgt aatcttgatt gaaagtttac ttttgactgg gcatggagct catgcatgta 111360 atcccagcgc tttgggaggc tggggcagga ggattacttg agtccaggag tttgagacca 111420 gcctgggcaa cacagggaga cctcttctct acaaaaaata aaattagccg ggcttggagg 111480 tgcgtgctga tagtcctagc tacttgacag actgaagtgt gaggatcact tgagcctggg 111540 aagttgaggc tgcagttagc caagatccat gccactgtgc tctagcctgg gcgacagaat 111600 gagaccctgt ctcaaaaaaa caaaaagaaa agaaaagttg actttttgcc agctgttagg 111660 aaaacatctg tggctctgga gggcggctgg tttaaagaaa aaaaaaaaca atcagacata 111720 cctgatatct acaagaggat aatgagctta gtatggtgtg tgtaggagcc tagaggagag 111780 aggctgggag gggattcttg gggaaaacgg tggttgagtt ggggttcaga ggcaagcccc 111840 taggtcttag gctgggcacg gtggctcatg cctgtaatcc cagcacttca ggatgctgag 111900 gtgggcggat cacctgaggt caggagttcg agaccaggct ggacatcatg atgaaaccct 111960 gtttctacta aaaatagagg agaatttgat ggccattcac agtcaaggga actgaacaca 112020 tcaaagggat tgccagaagg gcagaagtcc tgacttacag gtataaggag aaacagaaga 112080 ggagacaagg tgtggggtct accaggtggg caggcccatt gagtagaggg tacatggcat 112140 tcattgaagg attttcatca aggcagtctt ctggtaagat acggggaagt ccacaggcta 112200 attggaaaac agaaagaatg agatcatgga gacaaattta gggactgact ccgtctgtat 112260 taatttatac caggggtcag ccaagtgcaa cctgtggcta aatttggact gctatgcata 112320 catgtatggc ttgtgagcta acaaagtttt ttatggtttt aaatacttga gccaggtgcg 112380 gtggctcaca cctgtaatcc catcactttg ggaggccgag gcgggcgaat cacctgagtt 112440 tgggagttcg agaccagcct ggccaacatg gtgaaacccc gtctctatta aaaatacaaa 112500 aattagctgg gtgtggtggt gcatgcctgt agtcccagct actcaggagg ctgaggcagg 112560 agaatcattt gaacctggga ggcggaggtt gcagtgagcc gagatcatgc cattgcactc 112620 tagcctgggc aacagagtga gactctgtct caaaaaataa aataaataaa tacttgaaaa 112680 aagcaaaaga atagcattta ataaaaatta tataagattc aaatttcacg gtccataagt 112740 gaagttttat tggaatacac tcatgcccac ttgtttacat attgtctgtg actgctttca 112800 cacttcacac tacaaaggtt gagtagttgt gagtgatcgt cctcaaagcc taaaatattt 112860 actctctggc tctcctctct acagaaaaag gctgctgatc tctgcctgat tcattgattg 112920 attattattt gaaatggggt ttcactctgt catccaggct ataaagcagt ggcgtcatct 112980 cagctcactg caacctccac ccgccgggct caagcaatcc tatctcagcc ttctgagtag 113040 ctggaagcag aggcgtgtgc ctccgctccc agctaatctt ttgtattttt ggtagagacg 113100 gggtttcacc atatttccca ggctggtctt aaactcctga gctcaagtga tctgcctgcc 113160 tcagcctccc aaagtgctgg gattataggc atgagccacc gtgcttggct gacctctgat 113220 ttatatggcc agatgggggc aggtactcag ttgcttgtgc atattttgtt gggagatcac 113280 aagttagcaa gataaaagtg ctttcatcac agaggtttca gtctagtaga agttaaattt 113340 ttgtgccggg ttcagtggct cacacctgta atcacagcac tttgggaggc cgttgcaggc 113400 cggttgcctg acctcaggag ttcgagacca gcctgggcaa cacagtcaaa ccccatctct 113460 actaaaatac aaaaatctag ctgggcatgg cagcatgccc gtatagtccc agctactcgt 113520 gaggctgagg caggagaatt gcctgaaccc gggaggttga ggttgcagtg agccgagatc 113580 atgccgctac actccagcat gggcaacaga gcgagacttt gtctccaaaa aaaaaaaagt 113640 tcgatttttg tttaataggt gagatcatat gaaacataaa tataagtact gatgtaggga 113700 ttgtgctttg tgaatgggtc tctgcctgca aaacattcct gagaagcttt ctgaagggtt 113760 caagctgaga acagaaggat ggagaaagag attctgtaag ttaggaggca agaatctgag 113820 ctaagatttg gatgtgacag gaccatgagt ggatagggaa tgttttgttt cttgagtggg 113880 aagtgggaag cattttggga acaaggtaag gaagagagag gaggctgcag tgtttttaag 113940 gagtcctgcc cacgccaaga agtctggact ggaggtcatt tgctttaaac atgtcatctc 114000 aagcatgtgt gatctatttg gagcaaatat aatcaaggga agttttaaac aggagagttt 114060 tcagagcagt ggagtctgaa aagttgccct aaaataaggt tgagcataag aaagtccttc 114120 ttgcttctgg aaaaagtgga ctatgggtgc tcactctttg gggccagaca gagaagaatt 114180 aaaaatcatg ggctgggtgc ggtggctcac ccctgtaatc ccagtacttt gggaggccaa 114240 ggtgggtgga tcacgaggtc agttcaagac cagcctggcc aacatagtga aaaccacgtc 114300 tctactaaaa atacaaaaat tagctgggca tggtagcgca tgcctgaagt cccagctact 114360 tgagaggctg aggcaggaga atcacttgaa cccaggaggc ggaggttgtg gtaagccgag 114420 atcatgccac tgcactcccg cctgggcaac agagcaagac tctgtctcaa aaaaaaaaaa 114480 aaattgtgtt atttctccct tttgcaccta atctcccact gaagatgact gcaactttcc 114540 tgtgaattct gaacctgctg ccaaaagata cttctttata ttccatgatt ttgtgtaaaa 114600 ctttgtggtg agaattagag aaagcttaat ttgctgcttg gcatccagaa ttaggaggcc 114660 aagttaggct cccatgttaa ttttcagaaa gcccatgttc ctgatatctg gtagggatgg 114720 cggtgctgaa ctgtgaaggt gttggaaacc agaattttgg cagaaacgga gtcagatttg 114780 aacatggtac aaatttggac caagggccta gtgatagtta ggtcaggaaa ttggggactg 114840 tattggtcca ttcctgcact gctataaaga actacccgag cctgggtaat ttataaagaa 114900 aagaggttta attggctaat ggttctgaag gctctaaagg aatcatggct ggggagtccc 114960 taagaaactt gcatcatggc agaaggcaga ggggagtcag gcacatcttt acatggcaga 115020 agcaggagag agagagcaag gggaggaggt tccacacact ttcagacaac cagatcttgt 115080 gatatatcac aagaagagca ccaaagggga aatccacccc tgtgatctag tcacatccca 115140 ccaggcccca cgtccaacat tggggattac aatttgacat gaaatttgga tgggggcaca 115200 gactcaaacc acatcaggga ccaaagaaat attttactta ttttcagtta tcaatggaat 115260 ttactgctga tgagaaataa atgtatcttg ccagtaactt ataaagtaat aaaaccggcc 115320 aggtgcgatg gctcacgtgt gtaatcccag cactttggga ggctgaggta ggtggatcat 115380 gaggtcagga gatcgagaca atcctggcca acgtggtgaa actctctcta ctaaacatac 115440 aaaaattagc tgggcatggt ggtgcgtgcc tctaattcca gctacttggg aggctgaggc 115500 aggagaatca cttgaaccag ggagccggag attgcagcaa gacgagatca tgccacacca 115560 ctccagcctg gcgacagagc gagactccgt ctaaaacaaa caaacaaaca aaaaaatcaa 115620 aacaatttcc ctagaaatgt ataattattg acacttttta gtatttaaaa aattttcagt 115680 gataccctgt atttacaaaa caaaacaaaa caaaaaaaac gaaaaagcaa gacaaaaaca 115740 aaacaggcat ggtgatgtgc acctgtagtc ccagctactc aggaggctga ggtgggagga 115800 ctgcttgagc ctaagagttc aagccatgat ctcaccactg tactctagcc tggatgacag 115860 agcaagactg tctctaaaaa tttttttaat taaaaaaaaa tttcatcttg acttgctttt 115920 catgtgaatc tagtgtattt gctacttttt gataatgctt tgcacttttt aaattgtaaa 115980 aacattacat aaaattttca tcttacccgt ttcaggggca ctaagtgcat tcacattgat 116040 gtgcaaccat caccactgtc tagctctaga actttttgtc ttacaaaact gaaaattgcc 116100 cattaaataa taactccgtt tcctcctccc cacaccccat cccctggcaa ccaccattct 116160 acttcctgtc tccatgacat ttgattagtc tggatatctc gtataaatgg aatcatacag 116220 tatttgtcct tttgtgacag gcttatttca ttctgtgtag tgtttccaaa attcatccat 116280 gttgtagcat gcatcagaat gtacttcctt tttgaggttg aatgatactc cattgcatgt 116340 atgcattaca ttttatttat taatccatca gtggatgttt aggttgcttc tgccttttgg 116400 gtaatgcaaa taatgctgct atgaacatgg gtgtgcagat acctctttga gtttctgctt 116460 ctaattcgtt tttttttttt ttgagctgga gccttgctct ttcgcccagg ctggagtcca 116520 gtgccacgcc atgatctcgg ctcactgcaa cctccacctc ccaggttcaa gcgattttcg 116580 cttgattctc ctgcctcagc ctctcaagta gctggaatta caggctcaaa ccaacacacc 116640 aggcgaactt tttatatttt tggtagattg ggggtttcac catgttggcc aggcaggtct 116700 caaactcttg aactcaagtg atccacccac cttggcctcc caaagtgctg gtattacagg 116760 tgtgagccac catgcctggc cttctgcttc taattctttt agatataacc ttgaagtgac 116820 agtgctaaat ctagcactgt ctggtcttga actcctgacc tcaagtgatc tgcctgcctt 116880 ggcctccgaa agtgctggga ttacatgtgt gagccaccat gcctggccaa ttgaagattt 116940 ttattactta cattttccca gaaagggggc atgccacact acaccacatc acgtgaggag 117000 cactaggttt tggtcaggag gcagaagata ggagtgaagg gaaaaatcta gggcaaagcc 117060 tttactgggg actccaaggg aaacacaggg caggtttgag cataggatgg gttagtttaa 117120 ataattctgg ttggctttgg gctacaggga tggtctctag tgacttggtt tgtgccctgg 117180 gtatatagaa tatgggaaat agtggccagc gagagttagc taaggagttg gctgggctac 117240 agactgggat tggttgtttg gcatatgaaa gacatgctta tagacaaatt gttattatat 117300 tcgagaatta gctagctttg ggaaggacat tctctcccat gatttgcaag gccctcaaaa 117360 gccagagcaa caaaaataca gaaaataaga tatagttaat ataattggct tggtgatgaa 117420 cggatcccaa atagtcaaac acagaagcta agaaaaccca gaacacatgg taattcttct 117480 gttgcatttt ttttaggaaa ccacatagtg ttttgcatag tggctgtaaa aattttccat 117540 tcctaccaac attatacaag gttttcaatt cctctggtct tcaccatgac ttacgttctg 117600 tttcttctgt gttttatagt agccatccaa atgggtgtga agtggtatct cactgtgatt 117660 ttgattttga ttttgatttc cctgatgatt agtgatgctg agcatctttg gatgtgcttc 117720 ttggccattt gtatgtcttt ggagaattct tattaagacg tttgcccatt tttatgtatg 117780 tatatatgta tgtatttatt tattgagatg gagtctcttt ctgttgccca ggctggtgtg 117840 caatggccca atctcggctc actgcaacct ccgtctcctg ggatcaagca attctcctgc 117900 ctcaacctca tgagtagctg agattacaga tgtgcaccac catgcctggt caatttttgt 117960 atctttagta gagacggggt ttcaccgtgt taaccacgct ggtctcgaac tcctgacttc 118020 gaatgatcca cccacctcgg cctcccaaag tactgggatt acaggcgtga gccgctgcac 118080 ctggcttggc ccattttaaa atcaggtttt tttttttttt aaagttgatt atagaattct 118140 tctttttttt tttttctttt tgatacagag tctcactcta tcgctcaggc tggagtacaa 118200 tggtgtgatc ttggctcact gcaacctcca ccttccgggt tcaagcaatt ctcttgcttc 118260 agcctcacaa gtaactggga ttacagacgt gtaccaccat gcccagctaa tttttgtatt 118320 tttattagag atgtgatttc accatgttgg ccaggctggt ctcaaaccat tggcctcctg 118380 tgattcactc accttggcct ccccaaatgc taggcttaca ggcatgagcc actgtgcctg 118440 gctgaggagt cttatatcta ttcggactat taacatctta tcaaatatat gatttgcaaa 118500 tattttctcc cattctgtgt gttgcctttt cactctgttg attgtgtcct ttgatgcaca 118560 gaaggttttg attttgatat actccagttt atctattttt gtgtttcctt agcttttggt 118620 gttgtagtca agaaatcatt gccaaatgca atgttatgaa gcgttttttc ctgacagttt 118680 tatagcttta ggtcttatat ttaggtctct gatccatttc aagttcattt ttgtatatga 118740 tgtaaggaaa gggtccaact tcattctttt gcatgtggat atccagtttt cccagtacca 118800 cgtgttgaaa aggctgtcct ttccccattg aaggtcttgg cacaattgtt gaaaatcatt 118860 tgaccatatg gaagagttta tttctgggat ctctattcta ttccagttgt ctatgttttg 118920 cattcttttt aaaaaatatt tttagtcttt acatttcaga atcagtattt caaatgtgac 118980 ttgtaggact acgtgcagtg aggaagattg ttaatcatcc tattctgacc aggagttctg 119040 acaactttgg tgctgtaggc ggtgtctaag gcaggtgtca gcaaattttc ctctaaagga 119100 gctgtgtgtg tgtgtgtgtg tttgtgtgtg tgagtgaaaa agaggtgaga tttattttaa 119160 atttatttta agaaattggc ttacatgatg gtacagtctt gcaagtcaaa aatctgcaga 119220 ctaggctggc agtctggaga cccagggaag agttgcggtg ttaagtgtta agtctgaaac 119280 tagtctgaag gcagaattcc ctctcttcct caagagatct taatctgttt tcttttgttt 119340 ttgtttttgt tttgagacag agtctcacag cccaggctgg agtgcagtgg cacaatcttg 119400 gctcgctgca accttcgcct cccaggttca agcgactctc ctacctcagc ctcctgagta 119460 gctgagacca caggtgcaca ctaccatgcc tggctaattt ttgtattttt agtagatacg 119520 gggttttaac atgttggcta ggctggtctt gaactcctga gctcaggtga tccatctgcc 119580 ttggcctccc aaagtgctgg gattataggc gtgagccact gcacccggcc taacaatgac 119640 attttatata cacacaggca catacacaaa cctatttata aaagatgaaa tactcaagac 119700 aattacagtt ctgatttctg taactggtca ggtggtcaca gctcatattt gtaattacct 119760 ttgtctacta ctcattatgt atttccattg tcctcagcaa gcaccacggc tggttgtgat 119820 tatttatctg gtggggtgac ccaaaccttt gatttctgaa gggtctaggc cagtcatagt 119880 cctgcctgaa tttcgttgtt agagttttcc atgggctttg gtcacagagc ttggttaatc 119940 ctgaaatacc ctaagggatc ccttgtactt catatgtatt cttccttact tcctttgtga 120000 agcagaagtc cagtttctcc ttggtaatca ggatgagtgg cactagccag cacaacaatt 120060 cccttctttg ttgattcaaa ggcatgagga gcctaaaagg gttagatggc agttttttgt 120120 ttttatttat ttatttattt atttattttt tagacagagt ctcactctgt cacccaggct 120180 gcagtgcagt ggcgcaatct cagctcactg caacctctgc tgcccggggt tcaaacaatt 120240 cttctgcctc agcctcccca gtagttggga ttacaggtgc ctgccactgt gcccagctaa 120300 tttttgtatt ttcagtagag atggggtttc accatcttgg ccaggctggt cttgaactcc 120360 tgacctcgtg atccacccac cttggcctcc caaagtgctg ggattacagg catgagccac 120420 cgtgcccggc ctagatggca gtcctaactt ctacttcagt ccaattactg ctatatctac 120480 tgatggaaat attcctgctg ttggaactaa gactgccaga ccagaagagt atgagatcat 120540 ggggacagga aacacaaatt ttgctagttg gtcaactagg gatatttgtg gagggctgcc 120600 actcccattt ctatcttttg gtttctagac ttgtcaaccc cgactatggg agaaacagca 120660 atatattgga cactgactca gacagtatac agcctcctga aaagccttac cccagtcctg 120720 taaagtatta ccaaatagct ggtactgtaa ctgaatcttc aaaaggcctt tccaccattc 120780 tatgaaatca tctgccttag gatggcgggg aacatggtaa gaccaccaaa ttccatgagc 120840 atgggcccat tgctgcattt cctttgctat gaagtgagtt ccttggtcag aagcgatgtt 120900 gtttggaata ctatgatagt ggttaaggca ttttgtgatt ttacagaggg aacttttgac 120960 agaagcattg catgcagtgt aagcaaatct gtatccagag taagcatctg ttctagtcag 121020 gacaaaacac tggcccttcc atgatggagg ggattcagtg taatcaacct gccaccaggt 121080 agctacctga tcactgtggg gaatggtacc atagtggaga ctcagtgttg gtctctgctg 121140 agggtagatt gggcactcag tggtggccat agttaggttg gtcttggtga atgggagttc 121200 atgtggccaa acccatgcgt aaccttcatc cctgccatca tggccacttc gtttataatc 121260 ccattgggca atgacagaaa aatgagcctg actgtacata tgaaacaggt caccctatcc 121320 actttgtcat aaaaatcctc ctctgctgag tgggcattca catggccaca aatgtcttta 121380 cctttttttt tttttggggc tgatttagag gggtctatct ataagtccat ctatctcttc 121440 ccaaggcttc cttgtcacca attttccaat catgctcctt ccacattact gaccagccaa 121500 accattgacc acggcctata aattggtata taattgtata tctggccata tgtccttcca 121560 aacaaaataa acaaccagga acactgtccc aagctttacc cactgggagg atttgtcttc 121620 accactcttc ttcagggagg tcttcagaaa ggctctgtag tgcagcagtt gtccacttct 121680 gggtggtatg tgcatgtttt gtagaaccat ctgtaaacca ggcctgagtc ttctcttttt 121740 ccatcatctg attgaaggga accccccatg agccataggt gcagctggga tagagaaagc 121800 agtgtagcag gagtgggggc cgtggacatt tgagccactt cttcatgtga cttagttgtg 121860 tcttcagatc atgttctggc tgtgtaggct taactttaca gctgggctgg taagataaca 121920 cccagttcat gaagggcagc ttaggttaca tggtaacttg gtgtcctatg gttaagcctt 121980 tagtctccac taatgcccag tagcaggcca acagctgttt ctcaaaagga gggtagttaa 122040 ctacagagga tagcagggct ttgctccaat atcctaaagg cctatgctgc aacttaccaa 122100 tgggggcctg caaaaagctc caaaagacat tactgtctgc tactgacact tcaagcatta 122160 ttggttcttt tttttttaat ttttttattt ttcgagacag ggtctcgccc tgtttcccag 122220 gctggagtgc agtggcatga tcctggctca ctgcagccgc tgtctcccag gttcaagcaa 122280 ttctcatgcc tcagcctcct gagtagctgg gattacaggg gtgcactacc atactcagct 122340 aatttttgta tttttagtag agacggggtt tcaccacgtt gactaggctg gtcttgaact 122400 cctgacctca agtgatctat ctgcctcagc ctcccagagt gctgggatta caggcatgag 122460 ccaccacacc tggctgcatc attggttctt gcagaatcat gtgaccatag aggcagagaa 122520 atttatgttg cagcctggac ctgttgcaga agcttctgtt gttttgggat ccactcaaaa 122580 ctacagcttt tcaggtcatt aatgtagcac atgagctggg tgtttgaatc cctgagctaa 122640 ttttccccct actttgttca gtgaaattag gtgcaactag acagtctcat tatacttgtt 122700 agtttgacaa aatgtttgaa ggtatcatac atgttaaccc agaaccttgc cttttatact 122760 tatttaattt aaagtatctg ggctgggcgt tgtgggatcc cagcactttg ggaggccaag 122820 gtgggtggat cacctgaggt caggagttcg agagtggcct ggccaacatg gtgaaatccc 122880 atctgtacta aaaatacaaa aagcaattag ctagtgttct tttgattact cgtaattaat 122940 gcctttaaat ctagttagtt tagagtacca atttcagaaa ccaaccccag aactaattca 123000 gaaaatttat tcttaagatc tggttcaggt agagctactc ttgctaccga aatctgtgtg 123060 tgttagggtt ctccagaaaa acaaaatgaa ctaacaggat gtgtatagtc tcagtctctg 123120 tttctctttc tcagaattgg tcatgtggtt atggaggctg gctagtccaa aatcttcaga 123180 gcaggctatg gattcaggga agagttgatg ttgtagctct agaccaaggg cagtctggag 123240 agaatttcat cttctttttc tttggtttgt tttctcttat gggtttcaat tgaatggatg 123300 aggtccaccc atattaaaga aggtatctgc tttactcaaa gtctactgat ttaaatgtta 123360 atcccatctc aaaacatgcc atcgtggcac catccaggtt aatgtttgac caaatatctg 123420 ggtaccatgg cctagcccca ttgacacata agatcactat cacagtcaga taacaaatgt 123480 ttagctttgt gggtcatatg gtttatgtta caactactca actgtgtggt tgtagtcata 123540 gacaatacat aaacaaatgg ctgtggctgt gttccaagaa cactttattt atagatacta 123600 aaatttgaac ttcatataat gttcacatca taaaataaac ttttccttgg atcctttcct 123660 cctttcctcc tctccccctt tcccccaccc accatgtaaa aaaaaaaaaa aaaaaaaaaa 123720 gtaccacagc cagttgcaat ggtaggtacc tgtgcatatc actatgcctg taatcccacc 123780 tacttgagag gctgaggcag gaggatcact tgagcccagg actgcaaggt tatattgtgc 123840 tataattaaa cctgtgatcg tgccactgca ctccagcctg tgcaatatag aaaggcccca 123900 tctctttaaa aaaaaaatat acaggcagca ggcaggattt ggcatagttt gctgaccgtc 123960 aagggctctc ttttctaaaa cataggcatg gtaagaatat gtgcaaaggc catgggtgaa 124020 gagcttttta ttttgttgct tgtgttccag ttggtgcatt ctcaagagta ggtactttct 124080 tttcttgttc attctcttcc tgagcctatc ttgggatttt ctaagaaggt tgctattagt 124140 ctagtctttt tccagctgct ccctagattg aggcgggaga ggagaaattc agcaaagatt 124200 tctctctcct catcaaggct gtcccttgcc tgctttcctg tgggacagat ggtgcatgta 124260 ggcaaaaggc tggaacatgt tggctgctcc tgttacttgg tgctttgagc agaaaggcct 124320 gttgggttag ttcctgggct ccagtgctca atgtgtgtgt gtcctgtttt gtgtttttac 124380 ccatctttct gccttggctt taggtttata tgtttgcatt tataaaaact tcttatggaa 124440 tagaattata atgaagagga gcagcaaaga gttgtggttg agagctggca gtactggaat 124500 cagaatgctt ggcttgaatc tgggctcaaa tgcttgagag ctgtgtgact ttgagtacgg 124560 ttcttttctt ttctgggcat cagtttccta atctgtaaaa gggatggaaa tagggccagg 124620 catggttcct tatgcctgta atcccaggta ctcagaaggc tgaggtggga ggatagcttc 124680 agcctaggag gtcgaggctg cagtgaccca tgattgtgcc actgcactct agcctgggta 124740 acagagtgag accctgtctc taaaaaaaat aaaaagaaaa gatggaaatg aaatagtaac 124800 tcacacggtt tttttgtttt gttttgtttt tttgagacga agtcttggaa tctcactcta 124860 tcacccagac tagagtgcag tgatgtaatc atggctcgtt gtagccttga cttcctgtgc 124920 tcaagcaatt ttcctgtccc aacttcctga gtggctggag ctacaggcac gtgctaccat 124980 gcccagctaa tttttgtatt tttagtagag atggggtctc cctatgttat gcaggctagt 125040 ctctaactcc aaggctcagg tgatccctct gctcagcctc ccaaaatatt gggattatag 125100 gcatgagcct gcagtggcca tcacatggtt tttatttttt gttttttatt tatttttaat 125160 tttttatgga tctagtcctg aatccagaac atgattttta aatgaactaa tgttaaagta 125220 cttagaaaag tatctgctgc atagtaagga tatgtggttg tacaataaat aaaaataaag 125280 agagctgctc acatagagtg cagatttcaa accatctagt ctttctcgtt ttattacatt 125340 gaatttctgc ttctgaattt ttaattttgt tataagaagg atgttagtcc ctctaaagta 125400 tcatttccaa tattttgttt atgttccata aattttaagg ttattttact tcaaattatt 125460 ttataatgta tatgcctttt atatttgttt tagttatatc aaaatgcagc tttcaaaaat 125520 attttagtgt gtataattat ttcagattac tattagtaga agtgcttttt taaaagacaa 125580 atattatatt taagagaccc tgccacaaaa gtactcctca tggaagggaa gatggactgg 125640 ggatgatgtg gcagttatac agggaaaact tcacattatt ttgtatttaa aacataacct 125700 gaggctgggt gcggtggctc acgcctgtaa tcccagcact ttgggaggca gaggcaagtg 125760 gatcacgagg tcaggagttc aagaccagcc tgcccactat ggtgaatccc cgtctctact 125820 aaaaatacaa aaattagctg ggcatggtga catgcacctg tagtcccagc tgcttgggag 125880 gctgaggtag agaattgcct gaacccggga ggcggaggtt gcagtgagct gagatcgtgc 125940 tattgcactc cagcctgggc aacagagtga gactctgtct caaaaagaaa aaaaccaaaa 126000 cagaaaaaca taacctaatt ttatattttg ttttgtcata cagttgtatt tgttttaaaa 126060 tatctttcca ccccttccaa aagtatttta tccaagtagc agcacatctt atttccatgt 126120 ctgggttgga ctttatttat acttgtctga aactaaggaa aaagaaagta atttatatca 126180 gttaaaagac ctctacttct caataagtta gggggcggag gaatgggtct caatctacca 126240 ctcacttttc tgctagaatt tttttttata ttgatacctc ccattctttt tttattttat 126300 tttatttatt attattatac tttaagtttt agggtacatg tgcacaatgt gcagattagt 126360 tacataggta tacatgtgcc atgctgtaga atttcttaat gttgcatcag tgtttcacaa 126420 tgtaatcgaa aactcaaaat agcaatcttc cttttttatt ttattttatt ttatttatgt 126480 tttgagatgg agtctcactc tgtcgctcag gctggacagt gcagtggcat gatcttggct 126540 cactgcaacc tccagctccc aggttcgagt gattctcctg cctcagcctc ctgagtagct 126600 gggactacag atgcatgcca ccatgcccag ttaatttttg tatttttagt atagacgggg 126660 tttcatcatg ttggccagga tggtctgaat ctcctgacct cgtgatctgc ccgcctcggc 126720 ttcccaaagt gctgggatta caggtgtgag ccaccgcacc tggcctcaga acagtttata 126780 tttaaaaatt atttcaaaga taggagagag ttcccatgtg tctcatatgt ttcccctatt 126840 aacatgttac gcttgtttca ttgatgtacc aatattggta catttttatt aactgaaatt 126900 tatactttat ccagatgtct ttggtttttc taaaataccc tttttctgtt ccaggatctc 126960 acccaggaaa tcacagtaca gctagtactc atgtgtctca aggttgttct tggttgtgac 127020 attttctcac tttgttttga tgaccttgac agttttgggg attactggtc gaatgtttgt 127080 agaatgtccc tcaattaggg tttttaaaaa ctgatttata attcacatag tataaaattt 127140 acccttttaa aatatataat tcagtgcttt tgagtatatt cacaacgttt cccaaccatc 127200 ctatggttgg aaaattagat aacctactaa ttccacaaaa tccagaatat tttgatcatc 127260 ccagaaagaa acctcataac caacagcaat tactctcctt tcactcctct cccatcccct 127320 gaaaatcact aatctgcttt ctgtctatat ggatttgcct attctttttt tttttttttt 127380 tttttttttt tttgagatag agtctcactc tctcacctag gctggagtgc agtggcgcaa 127440 tctcggctca ttgcaacctc cgtctcctgg gttcaagtga tcctcctgcc tcagcctcct 127500 gagtagctgg gattgcaggc acgtgccacc acacccggct attttttgta tttttagtag 127560 agacaaggtt ttgccatgtc ggccaggctg gtcttgaact cctgacctta ggtgatccac 127620 ctgcctcggc ctcccaaagt gctgggatta caggcgtgag ccaccacact tggcctggat 127680 ttgccaatcc ttaacagaac atataaaaag aaccataaaa acgcctgaca tgttgcctca 127740 tgtctgcaat cccagtactt tgggaggcca aagtgggatg attttttgag tgtaggagtt 127800 ggagacctct ctgggcaaca tagttagacc aggtctctac aaaaaaataa aaaaattacc 127860 tgggcatggt ggtgcatgcc tgtagtccca gctactaagg aagctgaggt gggaggatta 127920 cttgagccca ggagatggag gctgcagtaa gccatgattg tgccaatgca ctccagcctg 127980 ggtgacagag tgacactcta tctcaaaaca aacaaacaaa aaaccccata atatgtggcc 128040 tttttctgtc tagctgcttt cactcagcat aatgttgtca gggttcttcc atgttgtttc 128100 atgaatcaac actccattcc tttttatagc agaatgatat tccattgtac catgccatag 128160 ttgtttcctt tttcttttct ttctttcttt ttttttttgg agaacgggtc tcactctgtt 128220 gcccaggcta aagtgcaatg gtgtaatcat agttcactgc agcctcaacc tccctggctc 128280 aagcagtcct cccacctcag tttgggtagc tgggactaga ggtgcacacc actatgccta 128340 actaattaaa aaaaaatttt tagtagaaat ggagtcttgc tatcagggag atcttggact 128400 cctgagttca agcaatcctc tcgccttggc ttccaaaagt gttgggactg caggcatgag 128460 ccattgcacc tggcctcaca ttttgtttat tcattcatca gttgatgagc atttgagttg 128520 tttccagttt ttaacttttt ttttttttga gacggagtct cactctgtca cccaggctgg 128580 agtgcaatgg cagggtcttg gctcactgca acctccgcct cctgggttca agcgattctc 128640 ccacctcagc ctcccaagta gctgggacta caggtgcgtg ccctcacacc cggctaattt 128700 ttgtattttt agtagagatg gggtttcact gtgttggcca ggctggtctc gaactcctga 128760 cctcgtgatc agccagcctc agcctcctaa agtgctggga ttacagtcat gagccaccac 128820 cagtttttta gctattataa ataaggctgc tatgaaaatg catatacatg tttttgcatt 128880 aagatatgtt ctcatttctt tttttttttt tttttttttt ggtgacaggt tttgctccat 128940 cacccaggcg gagtgcagtg gtgccatcac agcttactgc agtctccacc tctcaggctc 129000 aagtgattct cctacctcag cctcccgagt agctgggacc agaggtgtgc aacaccacat 129060 ttggcttttt tattttttat tttgtagaga cgagtcttgc tatgttgccc aggctggtct 129120 cgaactcctg gattcaagcg atctgcctgc ctcagcctcc caaaggattg ggattacagg 129180 cttgagcccc tgtgcccggc ccctatgttt tccttttttt tttttttaaa tttgaaacgg 129240 agtcctgctc tgtcgcccag gctggagtgc agtggtgcaa tctccctcac cgcgacctct 129300 gcctcccggg ctcaagggag tctttagtct cagtcccaag cagctgggac tgcaggcgcc 129360 cgccaccatg cctggctaat ttttgtattt tttagtagag acagagtttt accatgttgg 129420 tcaggctgat cacgaacctc ctgatctcag gtgatccacc tgtctcggcc tcccaaagtg 129480 ctgatattac aggcgtgtga accaccgtgc ctggccgttt tcatttcttt gtgatctgct 129540 taggagtaga attgtaggtc atatggtaac ttcagggtta acatttgtaa gcattgccaa 129600 actcttccac tgtggctgtg ctgtttcaca tcccaatcag cagtgttaga gggttccaat 129660 ttctccacct cctccacaac ccttgtcatt gtctttttaa ttctagcccc aagtggcatc 129720 tcattgtggt tttcatttgt acttctctaa tgacttaacg attgtgtctt ttcatgtgct 129780 tattggccat tggtatttaa gaactatttt aatcctttgc ccattaaaaa aaaatgtttt 129840 tgtcctttta ttgttgaata gtaacacttt tttttttttt tgagacagtc tcactctatt 129900 acccaggcta gagtgcagtg gcgtgatctg ggcttactgc aatctctgcc tcctgggttc 129960 aagggattct cctgcctcag cctcccgagt agctgggact acagacatgt gccaccatgc 130020 ccagctaatt ttcatacttc taataaagac ggggtttcac cacgttggcc agaatagtct 130080 cgaactgctg gcctcaagtg atctgcctgc ctcagtctcc caaagtgctg ggattacact 130140 tatgagtcac tgcgcccagc caagtactaa cacttcttta tacattctgg atactacact 130200 cctagtagct ttatgtttag caaatatttt ctcccattct cttggctgtc ttttcacttt 130260 cttaatgtcc cttgaatcga aaacttttat gtaactgtga tgaagttcag tttatttatt 130320 atttttggtt gcttttgttt taggtgtcat atctaagaaa ctgttgccta attcaaggtt 130380 acacggattt atatatatac acacatatat ttatacatgt atacataagt atacatggaa 130440 tatatgtgta aaatatacac atacacaaat gttatatatc acatttatac ataggtatat 130500 atgtgtacct gtatacatat ataacatgta tatatatgtt ctataacaag tgacttatat 130560 tttattgatc tattttgagt taatttttgt acatggtatg atgcaagggt tctgattagt 130620 ttttctagtc tcctttgtct attctgtaca gaatagtttt attgcagttt tagtgtcctt 130680 taagtacata accttaagtg tttggcttgg ggataaatgt agactttggg aaaattgaat 130740 tgttgggaga cctatcaggg tctactagca tgtcatagtg gagtttagtg gcaatgtctc 130800 cttctctgta tcttcactcc ccagttgtag gatatgttga atcagaccta ttattaacta 130860 acataaaata taagtgagcc taatggcagt tctctttaga ttttctgtaa agcccaggac 130920 acccattgtg acctctcaga ctccaaagcg aatttcctaa tggagtagaa caaacaggaa 130980 attatgagga aaggcagtca gagtttgaaa agagaacaca ccagaaacaa tggaagatag 131040 gtccaagaaa ctagataagt gcgagttgag aattgaatat aattttattt aattttaata 131100 atactttaat tgtaaaagta attcataatc actgcaaaaa gtaccaagca ctgtaaaaat 131160 taaaaataca aaacaatctc aaattgtgac agccaagaga aacctaaaga aacatgatta 131220 taatgtttgt ggcatgtaag tttggtgtcc acaatggaaa aaggatatta ggaaaaaaaa 131280 gaaatataag atatagaaat tagttaaaac aatgagaata aaaaatgaac acccaattcc 131340 tgctcctaga agaagtagta ctctaacatt tggtgaagtt ctaagagcca acatttttac 131400 ccagcttata ctaggacctg ttctaaatag tattttagct catttaattg ttaagccatt 131460 gtataaagta aacagaatcc cttcttttgt tacagattag gaatttaatg cacagagggt 131520 tagataactt gctcaaagta acattgtggt caagagtcaa agctagaatt tgaatcaaaa 131580 gagcctgagt ccaaaggcat ggttttcatc actggactat aatggtgtgt attctttcat 131640 aattttttca gtgtaaaact gaacatacag tatgctttta ttttatttat ttttttgaga 131700 tggagtcttg ccctgtcacc aggctggagt gcagtggtgt gatctcagct cactgcaacc 131760 tccgcctccc acgttcaagc aattctcctg cctcagcctc ccgagtagct aagattacag 131820 gcatgtgcca tcacgcccag ctaatttttc tgttttttgt agagatgggt ttcaccatgt 131880 tggccaggat ggtctcgatc tcctgacctc gtgatctgcc cacctcggcc tcccaaagtg 131940 ctgggaatac aggcgtaagc cactgtgccc agcctacatt ttatttttcg attgactccc 132000 gtgatcagag tcaacttccc atgttatttt atgtgaatat gtatcaatga actattagaa 132060 attgcaatgt ttttgtaggt caaaacaatt caatattgac aattttatat gattcagcct 132120 aatacatcat tttttccatc agccatattg catgttatta tttatatata cgtttattta 132180 gttagcctat ctgttctctg tgaggaacat tacacagttt ctgagatttt gttacgatag 132240 aagtcagcat tgataagcct ctgcgcacct gttttaatgt aggatcattg ggaactgagc 132300 agtagcttac agggcttggg aggggattta accatttagt caacctccac tcacatcacc 132360 ctcccttctt cgataatggg caattgagaa agggcaaatg tgtgtaaaaa ctatgcagat 132420 gcagtttcag gattattttc ttcttttctg cagtgtcttt tcccaagcta catcagcgtc 132480 taaattttgg agttactgat gcttccgtta tttctgcaga tagaatatta tgtcgtaaat 132540 aatgtttact tgtccattag tattatataa aagtgcctgt ttctccccac tccagctatc 132600 attgattatt ggtaaaaatt ttaatgtatc caattctaat aggcaaagaa aggctctcct 132660 acttagatct taggtggggg tctaagttca tatttttgtt ttacaaaaat tgaatagcca 132720 gtgtttttga gttgaatgat ctatccattc cgtataggag agtttaatta tattgtgatt 132780 ttgggggaga taattttcac aatttacccc ctcaaaatgt agaaagtaga aaaagggtag 132840 aaaaatcgca ccaaatttga acaatgtagc atgcttttag agttagggat attttctttt 132900 ggaaggattt caagtctggc gtatttgcat tgattgtggt tatggcgcat ttaacttttc 132960 caaaccagct tttttgtacc gcacatagga agacctgagg gtgagtgtaa attaggattg 133020 tttggccagt ggtgtgtgca aaaatttatt gtagaaccaa gaattatttc tttagtattt 133080 tacacatttt aaaaaacagg tagacatgtc cattgatccc aggttgctta tggtttctag 133140 aggccccctc tcattgcaac agtgctgtgg ggccctaggg gtccagtagc cccctccccc 133200 caggtcattc cggtgaggga gggagctggg acccctgcac tgcggcaaac aagcacgcct 133260 gcgcggccgc agaggcaggc tggcgcgcat gctcaggcgg ggatgtgtgc gaagcctgcc 133320 gctgctgcag cgagtctggc gcagagtgga gcggccgccg gagatgcctg acgcatctgt 133380 ctgaggagcg gtcagtgacg cgatggagcg ggcaaggtca gctgtgccgg tggcttctct 133440 caagagacag cctggggagc ggccactttt attcatcaga tattccaagt ttttaggact 133500 tggagtactg aataaacgga atttgggccc taaagtcctt tgttctggag aaccagatcc 133560 ggaatgttca gaggcttgct gttgtgccgt tctgccccga tggtatcctg tccgctcgca 133620 ttggggcgcg tcccccatcc gcccccaact gtggtgtcgc gacaggtcct attgcgggtg 133680 tctgcggtgg gaagggcggt ggtgactggg agcatgcggg gtaaccgcag tgggcaaggg 133740 acatgggtgg aggtgggtac atcagggtga ttgcagttcc gtgtggcgag ggtacgtggg 133800 gggaccagtg catagggatt ttaggcggag gtaggtatat tggagtgatt gtggcggggc 133860 gaaggtacgt gaagtgatcg gtatttaggg ggtgttgagc gcaggtaggt gtataatagt 133920 gaccactgcg tggtggagca gggtacgtgg ggcgactggg gggggaattc gtcgcagtga 133980 ccgaggcgag gaggctatgg cagtggacca gggggatgag tcggtgtgac agtggtgggg 134040 gttgtgttgg tggtcgcggc gcggggagag tccgtaggaa gtggctggga ggtaggggga 134100 aggcggcgac agtgggtatt ggcggcggtg ggcattggca gcgggtaggc atggcggtgg 134160 tggactttgg cggcggtagg catggcggcg gtgggcatgg catggaggcg gtgggcatgg 134220 cggccgcggg gcctgtcgct gtccggagtg actaagggac gctgaatgat tgctgtgtag 134280 aggagggggc atcagaaggg gcagtagcac agtccgcagc ctttaatttt cctgtgacct 134340 gcgatggtca tctggtttgc ctactgtggt ggtggtgctt ttttattaaa actgcgcaat 134400 gcctacactg ccgcaggggc tgcagaaatg cgtggaatcc ttgcgtaccc tttaggaacc 134460 ctcgctttag aggctatggc ataagaagac tggaatgatg tgcagaactt gcatttacag 134520 atcttttgac tgataggcca ggtgatgcct gggggttact tttttttcat tgtttctctc 134580 tgttgggaac caggtcttgg aaggctatgt cgaaataacc tgggggtctg tgttgcgtca 134640 ctgccattgt gcagctcctt caagatggcc gccgctgcag cggcttagat ctgcgcaagc 134700 gcttcagcgg gggggtggcc gcttcctccc tgtagagccg ccagtgggga gggggcaggt 134760 ggtgtgtgtt cagcttctgc tgtttcggag tttcagccgt accctcttta gggtgcagtg 134820 gtaaggagag gaagccggcc aaggtgggcg gctgccccct ccccaaagtg ctgcttggga 134880 aaggatgcag gttgcgcaga cgcagcagag gtgacagtcg cctccgcttg cagtggggcg 134940 agacgtgggg caggggagcg agggcttacg cagcttttgc ctggaaggaa tggcagccct 135000 ccccttcacc tggctgatac agcagctgtt cctttccggt tgtggcgcag tagagggggg 135060 aggagggaga tgggttggcg caggctccgc ctagcaagct tggcagccac cccttaccca 135120 cggtgcagca gtagaggact ggaggggaat gtggctagag gccaggcatt tgtaccacct 135180 ccgcctgtgt gggatggcag ctgcactggg ctactgcttt tcagctctgc agtaaactag 135240 agtggtggcg gcctggaggc catcaaaggt gcagccaccc caagacctgc tgtgctgttt 135300 cagcaagcct ccattaatga tagagatttt aaattggttt tctgactccc tggaaaatcg 135360 taccttttca tttttgtagt tcctctcttg gttgtattgt gcgctaattc tctattttca 135420 aactggactt gttaacccct tttttttaac tccctgtagt ctttgatttc cattcgacac 135480 atttaataaa tgtcaccatt taagattcag ttatccttct taatctctgg atagtccatt 135540 ctgatgcact gcatactttc cttaaatggg ttgggggaga ggacatcgtg atggctcttc 135600 ccgactaagg ttgaaaggtg tttcaaacac tggacctctt catcttctgg gagttgaaag 135660 ctgcaagttt tgtgctcaaa gagaataaaa gagaaaagtg gagacaatct tattggggtg 135720 gggttgtgct ttggatcagt tactgtcttt ttttggattt ttaaattaat gatcattttt 135780 gaagttggag ctactacaaa aatttggtga gaaaggttaa tgaataactg catttttata 135840 ttccagtact tttttaaaaa atcattttat tctaaggatt ttgtcttcct ttgcaggatt 135900 ttcagtgctt gccttttctg tatttacatt ttccctctat cataactggt atgtctggtt 135960 gcactgagtt gtaattaaca gaaaagttaa atctacgaag cccgaaaagc cttgttctgg 136020 aataatctat ttttgggtag ttttaaaaat agcaggagtc tgggatttta tatgatattt 136080 ataatttacc cttttttttc tgcttgcatg aagatagcag ttcacataca tatatttctt 136140 ggtttaactt ctggtcattt ggctatttgc aagctgagta tttagtctga tccgccattt 136200 tgtagtcttg cattcaggcc cgggatccta atatggcaga tccctttgga aaggcctctt 136260 gaagtttcaa ggtctgtgtc ctactcagtg aattggctct gtgctagggc tttttggagg 136320 cagggagtgg cagcccttcc tgtgatgcag aggaaggaag cttggttgag agacccttat 136380 gttgttgtct aaggcagggt actaactgat ttggatttat tcacagacct tgccttatct 136440 tgatttcact attctatctg accagtgtgt cattgccgaa atgttttcca catttatagt 136500 tactctgtat ctttatgttt cccttaccct gttccttttc ctaataaaca tctttgtttt 136560 acaaaaaatt ttgtttataa ggtgtcaagg atgccaagat aacctccttt gtttatcagc 136620 gccctctgtt tagctatttt ttaggaagaa tcatttaagc aggttgtgag tactgccctc 136680 aattacttgg acaatgaagt tttaaaaatc ttatttagac ctgtcactgg tcctgtctcc 136740 tttttttttt tttttgtggc ccagggccag aaagcttgag tgagaattgt tactacttaa 136800 ggtagcctct ctccatttct ggatgctagc tggctcaaag tttttttttt tttttttttt 136860 tttttttttt ttttaaatag accagggtct ccctatgttg tccaggctga actcgaactg 136920 ctagactcaa gctatatcct ctccctcctc agtctctctc tggccactgt ggctggccca 136980 aattctcttt ttgttaattc tcctcagatt tgttttggag gcaatgaggt ttcttatatt 137040 catggggtac agattagcag cctatcatta accttatttt tttgttttta ggagacaggg 137100 tctggctatg ttgcccaggt tggagtgcag tgatgcagtt atagctccct gtaacctcaa 137160 actcctggat caatctagac tcctgcctca gcctcccaag tgcctgttag tacaggcttg 137220 aggtactgtg cccagctaac tttttatttt tttgtagaga ggggtctcct tatgttgccc 137280 agactggtct cgaactcctg gactcaagca gtgcccctgc ctaggcctcc caaagtgctg 137340 gcattgcagc catgagccgc tatacctggc caactttgtt tatttttatt cttgagatct 137400 tagttaaatt ttatggaaaa tttaggccgt aataaaattg ggattccatt gctttttgct 137460 tttcaatata tttccggatt attactttca gtgtaagtga tctgagggca aacatttaac 137520 accctttcta tatgatgatt ttttcatgat gtcctcagtt tcataaaatg ttggtttctg 137580 tgttggggat gcagttagat aaatgcatgt gtgtgtgtat ctagaacatt caataaagta 137640 gtgttttcaa aatcttatag atgacatttt atatgtagat taaaaataag tagatttaag 137700 ccaggtgcgg tggctcatgt ctatagtccc agcacttttg gaggccaagg cagaaggatc 137760 actggagcct gggagttcaa gcttgggtat tgagaccccg tctctacatt taaaaaaagg 137820 taaattcaga aagttgaaat aatagaatat tttggtttga tggctatttc ctcagttgac 137880 ctcagacctt tcatattgag caactgccga atgggttctt tttgtttttt ggtaagacag 137940 tgtttgcagt tgtacactat tagattaatc atggtttagt tgatagtttc tttaattgta 138000 ttatattaag gtactacatt attagctgta tttgtgtgcc caccataatg tagcactgat 138060 cagtactaaa ttccttttta tggctgaaag acattcgttt ggatatatca tattttcttc 138120 attcgtaagt tgatggacat ttgagttgtt tccactcttt ggctattatg aataatgcta 138180 ctaggaacac gtataatacg tttaatacaa agaattagtt tcacaaggtt ttacttagcc 138240 ctcgtatatg ccaggttctt gaaattttgt ctttttggaa gtatgagagt agtggtagct 138300 gggaaggctg caggtataat agaaagaaca tgaactgtct gggcatggtg gctcatgcct 138360 gtaatcccag cactttggga ggccgaggtg ggtagatcac ctgagggcag gagctcgaca 138420 tcagcctggc caacatggtg aaaccctgtc tctactataa atacaaaaat tagctgggtg 138480 tggtggtgca tgcctgtaat cccagctact ttggaggctg agtttgggtc ttgtaatatt 138540 acttcatcta gcagtagagt tagtgtcata tgttactttc atgattaaca tttttaggaa 138600 gttggcaaag tctatatata acactttatg tttccaccag cagtttcccc acatccttta 138660 caaatattgt ggtgtcagat ggtggcattt cagtgggggt tttttcattt tgaggcaggg 138720 tctggctctg tcacccaggc tggtgtgcca gtggcatgat ctcaggtcac tgcaacctct 138780 gcctcctagg ctcaagcgcc ctctcacctt agcctcctga gtagctggta ccacaggcat 138840 gcaccaccac acccagctaa tttttgtatt tttttgtata gatgttgccc aagctggtct 138900 cctgagctca agtgatcgct ggcctcagcc ttccatgaac cattgcgccc tgcctcattg 138960 ggattttgat ttgcattttt tagtgactaa tgttcagcat catttcatat agattagcca 139020 cttgtatgtg tttggaggac tgtctattca agtgttttac ccatcgtagc aatagaattt 139080 gcccttttat tgttgagttg tgagagttcc ttacatattc tggataccaa acttgaaaaa 139140 atactttttt gaggtgtgag tgacatacaa aagctgtaga tagttaatgt taaaagttga 139200 tatgctaaga gataagtaca tgcctttgaa atcattctta tcaaaattag tggcataaat 139260 gtgtctgtca cctgaaaaag tttctttgcc tctccctacc ttcttttttt tcattgtttg 139320 gattttcttt ttgtttgttt tggatactag aaacttagct gtatgttaag caaatatttt 139380 ttcctattct ggttatcctt tcactttctt tagtgttttc ggaactttat tttttgatga 139440 agtccacttt attttttata ctgcttgtaa ttcaggtgtt atatttaata gaccattgtg 139500 taatcaaaag taataaacat tatcagtgta taaaatttta ccatttagaa atcaaatatg 139560 tgtgtatggc ttgattagaa catttaaact cttgaaagaa taaaacagct gtgcgttatt 139620 ggtaagctat tttaccaatc taaaagtcta acatgactta aaaacatcta gggttcagag 139680 aattattaat agcttttggc atgtatcttt gaattttgct tttgagatat tacttgtgtt 139740 actttagtga aaggtcctgc tgacctttct gatttatcat ctttaaaggt tcataggtgg 139800 tttctgcagt ccctaatatg gctagtctgg tgtgggattt catgttctgt tcccttgagc 139860 agccatttta tgaggggttc tgcagacgta acatggcggg ttttttgttt gtttgtttgt 139920 ttttgctatg tggatagttt ttagcttgag cagctcttct attgctttgc aaatcctaaa 139980 gaaagcacca tttgcatgtt tttttaaagt agatatttta taatttaaac tatgttctat 140040 tccactatat aagtatgtct actgtatcct aaaaatattt tttgaaacca ttttggaaat 140100 caggtttact gtttttgggg ggaaggtgag tagggtagtg gtggtatgta tgtatctaca 140160 tctgcataag tgggaatttt atatgtacgt gactacaaat agaggtagat atattatttt 140220 aatttcattt tctgattttt tttaaaacca gattttctga tgtcatgggc ttctaaaagg 140280 agaaaaaagt ggttatagca tagattatga ctgtttgaag gttaaagatc ttgtaataat 140340 tttaccttgt tttaattaga tttaaaaatc cattatatta aatgtagttc taaatataac 140400 cttgacaaat agttatttca tagattgatg cagtctacca aacaaatgcc tctcttttct 140460 gtttcaggga tcgcttacac ctgagacgaa ctacagaaca gcacgtacca gaggtggaag 140520 tccaagtcaa acgcagaagg actgcctcac tgagcaacca agagtgagta cagactgtgt 140580 tgggaacaaa tgcaagtcag aatctccttt cagattagaa caaaatatca tgcaatgagg 140640 ggattaaaat gaacataatt gaagaagcag acacatctaa tacagaagat gtagtaaaaa 140700 agcaatgaaa ttcttaacca tattatccta aaataattca ccctcttaaa gattttagta 140760 taattttctt ttttcctata cgtgggtaag tgcattttat ctttataaaa ttttgtaatt 140820 acccttcaac ataagcatac ttaaattttt ctgcattatt aaatcacttt gtatgcttgc 140880 aaaatgtact gtgcgctgaa gtgattaatt tacatattca ttcttgctct gtgatattta 140940 ggtgtttgtt tttggttagt gcatttattc tgttaaaatt taaaatacat ttgtgttttt 141000 tatcctgttt taagtatata tatgtggaat gtatatatag gatgtataca cagacacact 141060 cagacacata ttttaattta gatttctaga agggaaattt taattaaaaa taggtgaaca 141120 ttttaaatga cctaatacat atttagtcca cattgaaact ttggcatttt gtcattgcca 141180 ttaaaatttt gatggcatta aaatttgatg ccattaaaat tttgatcagt aggtagcatt 141240 tttttcttag ctacaattgt tttttttaat tataagtatt aaaaattcat gaagatgatt 141300 ctttttgtaa aacagttttg cataaaaagt aagtctcatt ttaaagcaac taccaactta 141360 actggccttt tcctccccag agataatcat taagtaaata gccatcagac cttgtcctat 141420 gcattgtgtg tgtagtgggg agagaggaag ggaggacatg ggacacattt gaagtttgtg 141480 tgcatacgac accgtgctgt ctgtattttg acaatatgtc ttggtgatct tttcatatca 141540 gtacacataa atctacctta ttttacaaag tgtgcgtggt gtgataacat tattattgta 141600 atcgttagct tgctgctgga tatttagttt gtttgcattg tttggctatt aacaatgaaa 141660 agaacagtca ctttgaaaac gcagtgtagg ccaggcatgg tggcccatgc ctgtaatccc 141720 agcactttgg gaggctaagc caggcggatc acaaggtcag gagttcgaga ccagcctggc 141780 caacatggtg aaaccccgtc tctcctaaaa atacaaaaat taaccgagtg tggtggcacg 141840 tgcctgtaat cccagctact tgggaggctg aggcaggaga attgtttgag cccaggagac 141900 ggaggttgca atgagctaag atggcaccac tgcactctag cctgggtgac agagcaagac 141960 tccatctcag gaaaaaaaaa aaaagaaaat gcagtgtatg aatactaatt tattttattt 142020 ttttcaaatt aaaggttttt cctcatagta aaaactgagt agtagtttgt gtgtcttttg 142080 ttatttcctc attttatatg tgaaaagttg agctggatgt ggtggctcat gcctctaatc 142140 ccagcatgtt gggaggctga ggtggatcac ttgagcccag gaggtggaga ccagcctggg 142200 caacatagag agacctcctc tctacagaaa aataaattag ccaggcgtgg tgttgtctac 142260 ctgtagtctc agctacctgg gaggctgaag tggaagggtc acttgatccc aggaggttga 142320 ggctgcagtg agccatgttt gtgccactgt actccagtct aggtgacaga atgagatcta 142380 gtctcaaaaa gaaaaaaaaa gttgtaaaac atctgttagc aagttttaaa ttatggtgag 142440 ggtaaagatt ttttttttat tttttcctat ttattttgcc gatttttact atagtgagta 142500 tatttaagta cattttcatt ttttaaaatt gctttggaag acgtatttta tgtacgtttt 142560 gtttgtatat tggtaaatat tttgaaagta ttttgtgtaa tataatttgt cctttatata 142620 taataggtta ttcgatcatt cattttattt gatatgaaat ctcttttttc atctcttcat 142680 tctttttgag acggagtttt gctcttgttg cccaggatgg agtgcaacct ccgcctacca 142740 agttcaagtg attctcctgc ctcagtctcc caagtaactg ggattatagg tgtgtgccac 142800 catgcctggc taattttgta tttttttagt agagacaggg tttctccatg ttggtcaggc 142860 tgggctcgaa ctcccgacct cagatgatcc gcccgccttg gtttctttcc caaagtgcta 142920 ggattacagg tgtgagccac tgcgcccagc ctctcccttc attcttttgc agctctgacg 142980 tttttttaaa gtgccattac tattccctga gtttctagag gtagttcaga gatggtggtg 143040 gaggtagggc tgaggtttag gactcttagg tttaggactg ttaagtgggt gaaggttcta 143100 tcttgctata tttttgttac agtttttttc ctatgtaacc tcagtgtgga ctaaataaca 143160 ggtagtctca tcctcatctt gttgtgggat gacgttagcc ttctaggcat cttgtccata 143220 tttatggaaa cattttgatg gttttgaaga agaaataact tgagtttttc ttatctgcac 143280 tgcatatata tgtacaaata ctgcagggtc ttgagttggg ggaatgatct gagtaaagtg 143340 tagagttagg gaaatagtat aatttttccc ccttgtgcgt tttcattttg agagtaattg 143400 gattatggaa tgggtaagca ggattggtta acactgcctc attgtccatg tgtttaggat 143460 tctcaggatt ggtatactta gaatgttata ctagaagtgt tcaatattta cccattcatc 143520 tcctacttcc taccaaatca taagtagtat tgggaggcag tcttcctgga ggagttgtgt 143580 ggttattagc cctaaagatc aatgaaggag gctgggtgcg gtggctcacg cctgtaatcc 143640 cagcactttg ggaggcgaag gtgggcagat cacctgaggt caggagttca agaccagcct 143700 ggccaacatg gtgaaacctc atctctagaa aaataaaaaa atcagccggg tgtggtagtg 143760 tgcacctgta atcccagcta ctcaggaggc tgaggtggaa gaatcgcttg aacctgggag 143820 gcaaaggttg cagtgagccg agatggtgcc attggctgtg cctgggtgac atagcaagac 143880 tccatctcaa aataaagtaa aaataaaaag ttcactgatt tattttaaat tttttattct 143940 gtctttcagt gtatttgtca ctaaattagc tcttattctt tggggctgga tgatgtatcg 144000 tgagttcgaa gggaaattgg aaattggagc tggagagttg tcttaatata ttttatgcta 144060 agcttcacat gtcttttcaa attaatattc tgcactctat gaattaaatt ctgtgtaggc 144120 tgcctcattt tctcagtctt taatcttcta ttgggttaca ggttagatct gagggggaca 144180 ttgcaataga gaattatctt acgtttcaag ataacattat atatattttt ttttactgaa 144240 acacttttta gacctttatg aataataatc agaaacttag ttgtcatttg taaacagagg 144300 ttagagtgga gaatgcccaa attaagattt atttattcag tgattagact atgaattaga 144360 gtataaagta gactatgaat tagagtgtga agatttagag gtatgtgcag tgcaattctg 144420 actacttgga gttagtgcaa atttcacagt tgtctagatg ccctccagaa cattcccctc 144480 aatgcagaca ccaactccaa gctccagggt tggcagggca cccacacttc cgaccaacag 144540 tctatagatt ctgaggtcct actattttct cagactttat aattgactaa ggttttataa 144600 atgactagta gatctcaaga aagtgctata cttactagtt ttttttataa aggatacaaa 144660 tgaacagatg catagagcaa aatctgggca ggtcccacac aaatcttccc tgtcctcagg 144720 atgcattacc tgcacattag cgtatatcac caatcaggaa gctcaccaga actccagatg 144780 tcgatgattt ttgttgggga ttcattatgt tgacaagatt gaatcactgg acatgtcact 144840 gaattcagtc agcaactctc ctgccctccc aggagggctt gctcaaaacc ccaacccttt 144900 agtctttgtt tgatcttttg tggcctggtt agtcaccatc ttgagacatc tcattaccaa 144960 gaactcaggt gtgatcctag ggacccacct tgagtaacaa acacatttct ttcactgggt 145020 aaattccaag gatgtatagg atgtataggt tacttcccag gaaccaggag caaaggccag 145080 ttaaattctt tattatacag aagcaatttt aaaatgttac tgaaaaacca tagaaaaaag 145140 tccaatttcc aaatccttac atgccaacaa gggcagcatt gttggtgatc ccccagctcc 145200 tcacctcaag gcaagctgtc atttcctgta tgtcttcctt ctcatcatca gatttcacag 145260 ccaggttact gattcatagg ggtatgtcga gggcttttgt ctggaattcc ctgcttacca 145320 gtagatgatt ggtttacata ttttaagagc ccttaaatag ccctggaagt tctatatttc 145380 aggtagtgac ttgtcaggag gatcaatatg aaggacggcc taaacatctc cctgcaaatg 145440 ctttagcagc atctccctcc cctcacccct ggggagaaag gattgttcac acaggataat 145500 ttgaaagtga gtgactatat atggtactga tggtgtttct tcaaggctgc cagctcttgt 145560 gtttttagtt cttttggaaa tatttctaga cttggtaagt atcttaagta tccactagtc 145620 ccttgtacaa tctctgtgta gagattcctg ttttgtgtta taatttctca taagatagtg 145680 tcatcctctg accctaaaga aagatcttct tccctgggcg tggtggctca cgcttgtaat 145740 cccagcactt tgggaggcca aagtgggtgg atcacctgag gtcatgagtt ccagatcagc 145800 ctggccaaca tggtgaaacc ccatctctac taaaaataca aaaaaattag ccgagagtgg 145860 tggcaggcac ctgtagtctc agctactcgg gaggctgaca ctggagaatg gcgtgaaccc 145920 aggaggcgga gcttgcagtg agcccagatc gtgccactgc actccagcct gggcgacaga 145980 gtgagactct gtcttaaaaa aaaaaaaaaa aattagctgg gtgtggtggt aggtgcctgt 146040 aatcccagct acttgggagg ctgaggcagg agaatcactt gaaccccgaa ggcagtgttt 146100 gtggtgagca gaaattgctt cattgcactc cagcctgggc aacagaatga gaccctgtct 146160 ggaaaaaaaa aaaaaaaaaa aaggaatatc ttcttaaatg taagggtacc tagttttctt 146220 tcatatggtt tcctataaag acaaatgtat ttttatcatt tatatatatt gtgctcttgt 146280 tgtaggtgtc agttgtaccc gaggcgttct cagcagcagc aagtacctgt ggtggatttc 146340 caggctgaac tgaggcaggc attcttagct gagacaccaa gaggtggtta aagccatatt 146400 ggagtagcga ggaatctgat tccaagcaaa aaccaggtta gagctaatgc agcaatgatc 146460 aagaataaag aatcattaaa gaatggggtg ttgggggttc tcttaattat cagtgacaca 146520 ttaatttttt tccttagagc ttcatacaat aaacacattg cagaaagttt tagaaagttt 146580 tgcaggacct taaattttct gccctgacac tttcgtcatg tttctgtatt ccagttattg 146640 tagcgcatgc ttttcaggta gttttctttt gcgttttttt taattatata aaaatatttc 146700 actataaatg gctcttgaat accctgttac tgaatgttta taatttcctt ttgtgggagg 146760 tgtcattttt ttctgccagt agtttgaaca aagctttagt agatagcttt gtataaaact 146820 tagaataatt ttttcaaata tgcagatgtg aaaataaatt gaatcaagga atatgaactt 146880 aaggtacatt tttctaaatt atattgcaaa gtattaaatt agtattcatt gctttcgaaa 146940 aataaagggc cagttacaac atactttcac agcattattt taattcaaat atggtttatg 147000 tcagtgaatt ataaatacac agcacataat taacaatgag tattagagaa tctaaatact 147060 ttctcatgct tatttactaa ttcctttttg ttttgtcttt ttctcacttt tctgttttaa 147120 ccaatgtatt tcctctttga atcagcagac aatgtaataa aaatattatt cataattttt 147180 caatgtgatg tagatttatt tagttctttt tatgttgctt tcatttttta ggaaaaagtt 147240 attacaaagt cgattttgat ttgttttctt gtttttcctc tgtgattttt ctttttttct 147300 actttaagtt ttagaatgcc ctcatttctg agagtttact atttactttt tacaaagtaa 147360 gagcagagag gaattgggtt tactgataaa ttccttctag ccttttttta agtctgtttt 147420 tgaagtatta tccttcaact tgaatcagtt aggcttgttt atggccacca ttttgagtta 147480 ttaattaatt tatttattta gagatgaagt ttcactctgt tgcccaggct ggagtgcagt 147540 ggtatggttt cggctcactg caacctctgc ctcccaggtt caactgattt tcctgcctca 147600 gcctcccaag tatctgggat tataggcacc caccaccaca cctggctaat ttttgtattt 147660 ttggtagaga cggggtttca ccatgttctc caggctggtc tcaaactcct gaactcaggt 147720 gatccacctg ccttggcctc tcaaagtgct gggattacag gcgtgaccta ccgcgcccgg 147780 cccattttga gtttaaatca aaggagacag aaattttctg agaaatcctc ctttcttgaa 147840 tcctttatac acaacatttt ctagcaattg cataagcaaa ttggaatcta atcattgtcc 147900 aaagcttttc ccttgagtaa gggaattttt cattgaatag gtgtgcacaa ctgatttttt 147960 actttttagg aattttttag cttctcagtt cagttcacag atttttgtaa atttttaaat 148020 acaacattta agtcatacat tatagtctgc aagtaggacc atctaatttt atgatactta 148080 attatatctt attctagtct caactgctag ttctacctaa atagtaccca ttactagtat 148140 tcctgtagaa gaagggttgg taatatatct ggaccactac ctgtgtctat aaatgaaatt 148200 ttattggaac acaactcagt tcatttatta tgttatcttt ggccacattg gtgctacggt 148260 ggtgcagctt tgagtagttg tgacagattg aatgacaggc aaagcctaaa atacttagta 148320 tcttgctatt taaaagaaaa taattggctg agttttattt tagaggagca gattgaaaga 148380 agaaaacacc aaagtggggg ccagtcaata tagtcataat gtcatagaag gtgataaaga 148440 atagattata gaagtatata cgaagtatac attacagcgt agacaatcag atgaatttct 148500 tggggaaggg atcagtctaa gagtcatgtt aaagtctgct gtggaggaag atgggtagtc 148560 tttaacaaca tttaaacact tcgtacccgt tttcattaaa aatgtaaggc acacgatggc 148620 caggaaaaat aagaaaataa actattaatg tggccgggtg tggtggctca cgcctgtcat 148680 cctagcactt ggggaggctg aggcaggtgg atcacctgag gtcagaagtt cgagaccaac 148740 ctggccacat ggcgaaaccc catctgttct aaaaatacaa atattagccg ggtgtagtgg 148800 gggacacctg taatcccagc tactcgggag gctgaggcag gagaatttct tgaaccctag 148860 gggcagaggt tgcattgagc agagattgtg ccactgcgct tcagcctgcg tgacagagca 148920 agacttctat ctcaaaaaaa aattgtgtta tgaatattct gtttttcttt ggtacctaaa 148980 tatttaccag ggtacatatc caactggata cctacctagt agttgggatg cagggtgtaa 149040 tattagtatg acttttaaac gtttttgtta cattgttttc taaacacatc atgagaagtg 149100 ctgatggcca ctaaaaatta gtagaccatt agtttctcag taccaccctt tgtattctgg 149160 tgtttttttg tttttgttaa ataaaccttt ccaataaagg aaatttgttt tcttgtgttt 149220 ttaattggaa ttattgtgta ttaatatttt gcatttagtt ttcttttgtc acttgttttt 149280 gcatactctt cgatggagga tctctatgga gaccctctat aattttaaat tttaacagat 149340 caatactgat attccatggt gtgtctcatt tgctatgtgt gccttggcca accctagtca 149400 tcttatttta ctatttgcta tgtgtgcttt ggccaaccct agtcatctta ttttactttt 149460 gaattaaagt agatttacat ttttatgtag tttaatcatt tgaaagtcta cagtttccta 149520 aagtttgaaa acttgtgctt ctgtgaggga taccagttcg ttaatttgct tatgtgccct 149580 ttgatctcag aagatacact atgactgctc atccatcctt gcagtgtgat gttgctactc 149640 tcgtcgcctt tctcatgaag ttttgttttc ttgtgctgta aagataaatt tgaccactct 149700 gcagtgattt attttcttct ttcacttaca aggtcatgac tacattgtat cacatttagg 149760 gatgagagag aactgtttct aaattccaaa tctgtctctt aagggaatcc ttttaactgc 149820 tgtaggaggt caactcctat tgtgagtaaa acatatatct cttctagcta tacaggttat 149880 tattatatta tgatatatat ataaatataa aataataatc tgtccctaat tctctaggtc 149940 ttcagttctt tgggccataa ctcacatccc tagatgtgtt tcatacctct ggaccgctaa 150000 gcttgtggga gttatttata tcctattgct caaggtcatt gccaaggtct gatttttcac 150060 aaaaaaattc caacctctgg cataaatggg ttaaaaacgg ctttagtgat gtagtgctga 150120 taaacataaa attcacccaa tttaagtgca tgaagcaatg atttaagtaa atttacagaa 150180 ctgtgcaatc attgccatga actactctgg aaacattttc atcaccacag taagatctgt 150240 cttgctcatt cacagtcatg atccttgttg tctctttgga tggctgaagg tcccaagtgt 150300 tgcagtgcta taaaaatgga tattgctggc tgggcgcagt ggctcatgcc tgtaatccta 150360 gcacttgggg aggctgaggc cggcaggtca cctgaagtca ggagttcgag actagcctgg 150420 ccaacgtagc gaaattcctt ctctgctaaa aatacaaaaa ttagccgggt gtggtggcgg 150480 gcgcctgtaa tcctagctac tcaggaggct gaggcaggag aaccacttga acccgggaag 150540 tggaggctgc agtgagccga gatcactcca ttgcactcca gcctgggcaa cagagtgaga 150600 ctctgtctca aaaaaaaaaa aaaaaggata ttgctaatga gtctcatata ccatgttttc 150660 ttggatttag actgctttat aaagaatcat aagataatat tcaaaacttc taagttatag 150720 tccttaaact cttactcata tttaggacag aaactacatt taatttttgt ggaggtcttt 150780 gtttgcttat ttgaaaagtt cttttgagat ctttataggt tttatttaat acatttttta 150840 atgtacagac atcagattca tggccactga atgacagcca ggcattagag tattcttttt 150900 tttttttttt ttttgagatg gagtttcact cttgctgccc aggctggagt gcaatggtgc 150960 gatctccgct caaaaagata cttttgaatc cttttcaaaa gtaatttgtg tttcattttt 151020 taattagtat gataagcact tcaagaccct ttacaattct ggctagattt ggttgccata 151080 tttaatagca ttttataaat aatggagaaa agggaaacat tatgcatgct tgattacggt 151140 catgagctgc attaacaatt ccgttcaaca acagactgca tatgtcagag cagtccctta 151200 agattacaaa accatgtttt cattgtgcct tctctctctt ccccaccacc cccaaccctg 151260 agatggagtc ttgctctgtt gcccaggctg gagtacagtg gtgccatctc agctcactgc 151320 aaactctgcc tcctggtttc aagcgattct cctgcctcag cctcctgagt agctgggatt 151380 acaggcgcct gccaccacac ccagctaatg tttgtatttt tagtagagat agggttttcg 151440 ccatgttggc caggctggtc ttgaattctt gacctcaggt gatccgccca cctcggtttc 151500 ccaaagtgtt gggattatgg gcgtgagcca ccacacccag cctcttctct gtttaacatt 151560 gtattgtgag tgttcatagt atgcaggata gtaacatgat atacaggttt gtagcctagg 151620 atctaccata ttgcctaaga gtatagtaga ctctgtgtat cctctaggtt tgtgtaagta 151680 cactgttcat actgtgatga aatcaccaaa tgcatttctc ctaatgtgtc cccattacgt 151740 gacttattta tttattttga gatgaagttt tgctcttgtc cctccttgtt gcccaggctg 151800 gagtgcagtg gcgcgatctc agctcactgc aacctctgcc tcccaggttc aagcgattct 151860 cctacctcag cctctcaagt agctgggatt acaggcaccc accaccatgc ctggctaatt 151920 tttttgtatt tctagcagag acgggatttc accatgttgg ccaggctggt ctcgaactct 151980 tgacctcagg tgatccacct gccttggcct cccctggtgc tgggattaca ggcgtgagcc 152040 acctcacccg gccgttaacg tgatttataa ctttgtcctt cattacttga tctatgaaag 152100 ttgtttatgt gagtctatat atatatattc catagtcatg tgttctcttt tgacatggga 152160 agtcttaggc aggtttataa cacacttggc tcttagtggg gaaagattac ctgccatcat 152220 cttgaagcga atttagggga agaaagaata ttgcaaatga caacataggt atttcagaaa 152280 aaaggaaaaa tctgaatgaa agagtaattg agatgttgat acagagatga cttcatatta 152340 attctgaact agagagagag acactacctt aaataaggat ggaaagaaaa atactaaatt 152400 tgggaaaatg acgcttagtt tttgaaacat ttaggaatta ctaggtaaaa taaaattcaa 152460 tgactttcat cagtcctaag tgtgtcaaat gtgagagtta agaatgaggg actagggaaa 152520 tgtggcagtc ccttggtgag gaagctagta tgagaggaag gatgtttttg aacgtgtctg 152580 tcatagtgat tttcatgcaa aattgtctgc ctgttttaaa acatggtaga ttgcagtgca 152640 gctttaacat gctttcctct gcaggctcca tctactcttt gaagcttctg cccagcttgc 152700 attgtttcta ggagaacctg cgtcatacct ttatctatag ccttccccta ggtcttcaga 152760 agcatcaagt tttaactgtg gacattggat ttggtggaac agcaatcatg gtaagctgta 152820 tgataaggct gagggttgaa atgtgctgta agggccgaaa gaaatagttt gccagcatgt 152880 gcagtgatct tgggttctga atgttagaaa taaggataca tccatggata tggattctca 152940 ttgcattgag tatcagctga agatgagctg atttttttat ttttattttt ttcagacggg 153000 gtcttgctct gtctcccagt ctggagtgca gtggtgcggt cttggctcac tgcaaccctg 153060 ggttcaagag attctcgtgc ctcagcctct ttattagaaa cagggtttca ctgtgttggc 153120 caggctggtc tcaggctcct gacctctggt gatccaccca cctcggcctc ccaaagtgct 153180 gggattacag gcatgagatg agccactgtg cctggccatg agaaatgttt catgatgtga 153240 gaaaatacag gagtttttgg tcatgattcc accagtggtg aaggactgtc ctgcagatga 153300 tggactctca ggtcagatta caatagaaat aaagagggct ttgaaaatgg aagggttttg 153360 gcattaacag tacagagaaa agcagtctgg agagagagaa caccctacat cattgtggtt 153420 tggtttactt aggggagtgg acagtttaga gcatgcatcg tcacagagaa ggataatcac 153480 ctgtaaggag gtgaaaattg gttcttgaga tgtgaaaaaa tacttcataa tcctttgtgg 153540 tcctccaaag agccatacta aatatggaag aatgttggtg aaaaaggaga gaatatttgt 153600 ttagttaagg aaaccaggct tagattatgt aagggtggag aagaaacagg agaagattag 153660 aagactaggg tgttggcaag ctgaacatga ctcttgtctt actgcttcta gactgttggc 153720 aagagtagca agatgctgca gcacattgac tatagaatga gatgtatcct gcaagatggc 153780 cgaatcttca ttggcacctt taaggctttt gacaagcata tgaatttgat cctctgtgat 153840 tgtgatgagt tcagaaagat caagtaaggc tgatttgggc aaatgggggt tggacacaga 153900 ggcagtggga agggaaggcc agagctggag taagggattt ccgagggtaa ctgaagtagt 153960 tagggaaact atggtagagc cagtctattg tttaacctct tgacctgatc tctgaattag 154020 gtcagagtct gcatctgaac tcttttaagt ttgtaaaaca atcatggatt tattactggg 154080 agtaaaagta tatgctatgg tcagaatact cgtatttatt tttaaaattg agaaaaatgc 154140 tatattaatt aattggttgg cttctgcagc agtcttagac caaatcttgg ttgaaatgga 154200 gaagaacagt tgttcttcat ggttgaggag ttgggatatg gttgccattt ggtatcctct 154260 ctttgcctat cactgttccc attatttcag ttctgtgtca cctgtcatta tgatttaatt 154320 atttaagtaa ttttttaaag aaatttccat tttaatgtgg aaacccaggt ttcaattttg 154380 tttttcttaa aaggtatttc acaaaagaaa ttagtcttgt tgtagtgtaa catcaaagga 154440 acattctgta aaagactaaa gttagattag aaaatagctt cactatttac ccttgtatat 154500 taactgtgtt tacagatatt ttttggcttg tttttcagtg ataactcagt aaatgtttag 154560 catcagttgt cttaattgat acttgaggtt gtataaatat tttgatgagt gagtgatcac 154620 taaaatttat ctcactaaaa tttaattctg atttgtaggc caaagaatgc gaagcaacca 154680 gagcgtgaag aaaagcgggt tttgggtctg gtgttgctgc gtggggagaa cttggtatcc 154740 atgactgtgg aggggccacc ccccaaagat gtaaggaaga tgtagggcag gacagaactt 154800 taatttgcag ggacatcata ttatgtgaga tgtctgaaat cagggtagag cagacacagt 154860 tcaacatgga ttgtcaaata aaatgtgcca ggcacttaat atcaattgtt ggttgcctat 154920 gctattcggg attaggggat ttttggtgaa ttattctatg tgctgggcat tacctaggta 154980 agggtaggag ttggtgattc atgtttgctt ggtatgttta taaaagaggt gttttcacaa 155040 tttgacaaat aatgtgcatt ttatacacaa gatacctcca tggtatactt gcttgtttgt 155100 tcatttggac acagaactaa tatgagatag gtgtcatggg aaaatggtgg agagaagtga 155160 tctctgatga ataagaatac tgagaacttg taaattgttt gattttaggc tatgaatttt 155220 cttgtttcag actggcattg ctcgggtacc acttgctgga gctgctggag gccctggggt 155280 tggtagggca gctggtagag gagtaccagc tggtgtgcca attccccagg cccctgctgg 155340 attggcaggc cctgtccgag gagttggggg accatcccag caggtgagga accagcagag 155400 ggttttatat tattgggaga atatgactaa gccggaggcc gaggagattt aaaaacctaa 155460 gtgtatgtgt catacaatgt aaacagcata tggtttagga ggaaccaaaa cacagatata 155520 tgggaggaag ggaataaaac tagctgctta aaatggtcat tgggtgatta aagttaccca 155580 ggttactctt ggcaagagta acttgccact agtggtgagt gaacagaatg catggatata 155640 ccacagttga aaagaccaaa gggctttttg gatgtcagtg tactaagatt agtttttaaa 155700 atatgggaat aggccgggtg cagtggctta cgcctgtaat ccagcacttt gggaggccga 155760 ggtgggcaga tcacttgagg tcaggagttc gacaccagcc cggcccacgt ggtgaaaacc 155820 ctatctctac taaaaataca aaaatcagct gtgtgtggtg gtgggtgcct gtaatcccag 155880 ctaccaggca gggagacagg agaatcgctt gaacccagga gtgggaggct gcagtgagct 155940 gagattgcgc cattacactc cagcctgggt gacaagagtg aaactgtctc aaaaaaaaac 156000 atgggaataa tgagagaagt acattgcaac agttgtttgt aactaattgg tcatttttct 156060 catttatttt ctgtgtttga ataatgtgaa ggtttgcatc gctttgactg tttcccgccc 156120 tgccttctca ggtaatgact ccacagggaa gaggcactgt agcagctgct gctgttgctg 156180 cgactgccag tattgctgga gccccaacac agtacccacc aggacggggc actccgcccc 156240 cacccgtcgg cagagcaacc ccacctccag gtaagggatt ggtgaacacg aagacgaact 156300 tgaatctctg atgagagata gcttactgat ttaagacaca gcctgagagc ctaagaattt 156360 ggggaatatg cttccttctt ctagatactg gtttttaatg aaagacatag aagagtaatt 156420 gtcatataga agttatttga ctctatcatt gttgtctggc ccatttcttt agggattatt 156480 tgggctaaat tctaactttt ctaagccatt ttatgaggcc tttatttcta ccatttttca 156540 ctgtaggcat tatggctcct ccacctggta tgagaccacc catgggccca ccaattgggc 156600 ttccccctgc tcgagggacg ccaataggca tgccgcctcc gggaatgaga ccccctccac 156660 caggcattag aggtgagtgg gagcataggg gtttgatggt tcagccaggc ccctgaatat 156720 gtgtatcctc tttttctcaa tgtttctatt tcctttccag gtccacctcc cccaggaatg 156780 cgtccaccaa gaccttagca tactgttgat ccatctcagt cactttttcc cctgcaatgc 156840 gtcttgtgaa attgtgtaga gtgtttgtga gctttttgtt ccctcattct gcattaataa 156900 tagctaataa taaatgcata gagcaattaa actgtgaggt actgttgtat atattttttt 156960 gcctgttgat tttgatgaga tcttaagtta ctgtggatga gggtgatgcc tattaagcag 157020 ttgattcaaa tcatattctc tttaattctt aggataaaaa ggttttctgc tatctaactt 157080 tcactttgtg cattgactgg tgttggttaa taatgttttc atgacccggg ggtttaagtg 157140 gttgtgctgc ttcacacatg gcctcctgct tctcatgttg ctatgtcaca ttatctgaag 157200 ggaagtgggg atgggatgaa aggccttgta aggccaccta tatactgaag gaagttgtag 157260 tgaatcacag tccatgctca ttacatatca aggcatttga aatagaagtt actctttttc 157320 ttgggatgtt gacctcagtt gatcaggttt tacagtgtcc tatgatcaga atagaggatg 157380 tgatactgga ataatcattt tctaccattg agtaagtatt tatttataaa ttactaaatg 157440 agtggaagat cctgggtact gggaggcagg aggttgcata tttgagttga taagttgtac 157500 tactgataat aaagataact gacacactaa aacatacttg gtacactgaa atacaaatta 157560 cggttatgtc cagtggtatc accaagtgac aaactgggag ctaaatagtt cagaaatgcc 157620 ctagtctcta ggtccagttt gaattggtta tggaacaaag aagccattta taaaagggaa 157680 gagattttta ggttttgcag ctaaggttta tagtaggcag cgagggaatg attcatagtg 157740 attgtagcag ttggtttacc aagcactaaa gagattggtg ttaactccat aatactgata 157800 gactgattgg aattacattt tttctcttga atttaccagg agtggttgtg aatgtcacct 157860 tttccatctt ttaaattaca tccttgcagg tggtaatcac tcaaggaaaa ggaattatca 157920 gagtaacaat agttcctgtt actgacttga tatggtctct gccagaatag cttctcagat 157980 taatggccac tctcaggtaa ggaaaataaa gaggcgaagc cttagttgct ttaggagatg 158040 atataataca ggtgtgacat cagtgttttc agaatttgta aatgttaaaa caaacttctt 158100 gatttaccaa agccacaacc aaagtacttt acctggatct ttcaagacag agcttctcag 158160 ttcagacaaa ttgactgatg ataagacaaa cacttttcct ctacaaaccg tggggtagta 158220 tgtagagaga cctgtgattt cttcccatac tgctctggaa ctacttctaa ttatactttt 158280 ttctttgttt gtttttgaag gggaagcatt tctccttgca ttggtttgct ggtatggatg 158340 gcccttagat tttggcatga gtgattatgc agcctatttg aagaaaacct gttttcagga 158400 cctttttaat taaatatggc ctgttacatg agttaaaggt aagttataag agctctagat 158460 tctgcaagat gcttgcttct tgtagttatt ttgcttggtg ataatacatt ttcttttgtc 158520 tggagcttcc tggacttttt gagaatcctg attgtgatga tataatagga gaaaacttgg 158580 gatatagata gtataattga gtgtggtgaa tcttttgtta tggaatgcta gtctaagctt 158640 ctgtgtgttt ccactaggga cacacatcaa catatcagtc ttaaaacatt cttggtagtt 158700 aatgcttgat gttacttaaa aatcatccta cattcttgca ttaaactaca tacacgtggc 158760 tgggcgcggt ggctcatgcc tgtaatccca gcactttggg aggccgaggc aggcagatcc 158820 cgaggtcaga agatcgagac catcctggct aacacggtga aacctcgtct ctacaaaaaa 158880 ttcaaaaaat tagccgggcg tggtggcagg cacctgtagt cccagctact cgggagcctg 158940 aggcaggaga atggtgtgaa cctggtggag cttgcagtga gccgagatcg cgccactgca 159000 ctccagcctg ggcgacagag taaaactctg tctcaaaaaa aaagaaaaaa aaaaaaaaaa 159060 gaaaatacat acatgtctca tctaaaacat ggttggtcaa caactttctg atttcctgat 159120 acacatttta ttaaccggct ccttaaatat atccatgttg catatcatgt ttgacatgct 159180 ttcattgtag cttatagaat aatttcaaat agaattttgg gataaaaatt atgctacctt 159240 aaaataggtt atgaagtatt tgaggtattc tctttttata tgataggtaa acttggcttg 159300 gaattaaaaa gattttgaaa gttgcttagg gagctccctg cttttgtgaa ctcattattc 159360 cttaattatg atgtcaaatt tcagaagttt gttattaaca taccggtatt ttgcttttta 159420 tagattcttg taatagaata ttacaagtag aaactgattt acatagataa ttatgtgaaa 159480 tagtgctgct tgactaggat tttcatgatc tcatttcaaa gattagcaaa aacacccttt 159540 acctggtatg tttacctctg atactacctt cactgatttc agcaggtagt cagttataat 159600 ccatggattg aagttttgat ttatttattt atttatttga gacagagtct cactctgttg 159660 cgcaagctgg agtacagtgg tgtgatcttg gctcacttta gcctctgcct tccgggctga 159720 agcgattctc ctgcctcagc ctcctgagta gctgggatta caggtgtggg ccaccacacc 159780 tggctaattt ttgtattttt ggtagagaca gggtttcacc atgttggcca ggttggtctc 159840 aaactcctga cctcaggtga tccgcccaac tcagcctccc gaagtgctgg gattacaggt 159900 gtgagccacc gcaccccgcc atgggttgaa gtttttaaat gcatgttttc cggtagttaa 159960 tacattgctt gattctgtct tataattgca tttcagttct cttcatcttg tccatacaca 160020 taataatgct tagtatataa taaagcaagg tatattttca tgggattttt gtagtgggag 160080 aatgacatct gagcctgaaa taggatattt gtgttgtaac tttttcagtg tcatacgata 160140 ccattttttg accacttagt tgatgcctct gaaaggaaga gagaatcaga tcgctaaaat 160200 ttgatgtgtc gtcagtgtgg atcctactca gtagtgtcac aacgaggctg aaaatcatat 160260 taagtgcttt taggacagaa acgtaaactg ctcaggtaaa ataaccttat aaagagaaat 160320 aagcatatat tgcagaggcc ttggctaggt tcatgatgac acaggacctt gtctgaacat 160380 aatgatttca aaatttgagc ttaaaaatga cactctgaaa tccagtcagt gtgcctcact 160440 agacttttcg atttcaagat tttctgcaga aaatgttttg aaaactttga atacttaaaa 160500 atggcaggtg tagtattgca ctttgctagt tgctcagata ccctttttta tttgtataga 160560 tattctgagt tccttttttt ttctacatgt tgtacgttgt cgaaagctaa aaggaaactt 160620 atccttggat cacggaaggc agaggcattt ggtgagatgg aaacaaggat gtgtaaaaat 160680 gagacgacca cctctcggat taaaaaaaaa aagtgccaga gttctagggt tctaagtgat 160740 gtccaggaag gaggaggaat aatatttatg gagcatatat tatggaacac agtgagtata 160800 gtacctgcct ttaaatgaat actgttggtt ttttaggaca gttgcttttt tttctttttt 160860 cttcagctgt gtgcagttga ttaacttgta cagagcctat cacacaatag atgtttaaga 160920 aatattaagt gaatgaatga ggcagcattg ctaatttttg tatagtgaga cagtatctca 160980 cagtccaggc tggagttcag tggcattaac ataactcact gcagccttga acacctgagc 161040 tcaaacgatc ctttcacctt atcctccaga gtagctggga ctacagtcgc gtgtcaacat 161100 gcctggctaa ttttagtttt ctaatttttt tagagttggg atctcactat gttgcttaga 161160 ctggtcttga actcctggcc tcatgccatc ctcttgcctc agctggtatt gtaggtgtga 161220 gccactgtgc caggtactaa ttttttttat gttagaaaac aagtttttag gtattttata 161280 gttacttcct tatgacaata tctcatcaga atctaggcct atctgatatc tgactccata 161340 cgtttatacc gtgtagtcag ccattcccag atagaggtca tttgagttac ttagtgttta 161400 ccagcacttg tttactacct tgcgatgata tttacagtgt atttttgggt atggttttgg 161460 ggttatttgg ttgttgttaa aatgcctgta atcccggcac tttgggaggt tgaggcgggt 161520 ggatcacctg aggtcaggag ttcgagccca gcctggccaa catggcgaaa ccctacctct 161580 actaaaaata caaaaattag cctggcgtgg tggcaggcac ctgtaatccc aactacgcag 161640 gaggctaagg caggagaatt gcttgaaccc gggaggcgga ggttgcagtg agccgagatc 161700 gcgccaatgg cactccattc agcttgagtg acagaggtga gactcccatc tcaaggtaaa 161760 aaaaaaaaat agaaatcagc aactgctatt tgagtttaca ggagtgagaa gtcctctctt 161820 gcatggtgag atggggaaca tttaattcaa tagaaatatt tgagaccagg tatggtggct 161880 caagcctgta atcccagcac tttgggaggc tgagttgggt ggatcacctg acatcaggag 161940 tttgagacta gcctggccaa catagcaata ccctgtctca aagatacaaa aattacccaa 162000 gcttggtggt gtgtgtctgt aatcccagct actcaggagg ctgaggcagg agaatcactt 162060 gaacctgggc ggcaaaggtt gcagtgagcc gagaccatgc cactgcactc cagcctgggt 162120 gacagagtga gactccgtct ggaaaaaaaa agaaaaaaat gagatataaa gttcaaagga 162180 tgtatttatt aagccaatat aaagtaaaga ggtggggaat gttgtagaag tatatgttga 162240 taaagggatc aggtggttgt acaataagaa gggggttgca gacatggaga aacagttctt 162300 ctagctcttc cactttcagt atcatctgtg tgggtcactg gaatcctttt tcacaatgcc 162360 tgcttgccca tgagttttaa gaactagtac agtgtagaaa tgattagtag gaaaaacttg 162420 gctgggttaa tttgctttgc tgagccgatt caacttaaaa agcgaggtcc atactaagtg 162480 cccaagaatc aagaaggagg ctcacatttg aacttgatgt ttagttaatg tgaatcattt 162540 tctgttgaac taatgagaat acagtgacct tgagggttag gttgtacatc tgaattgttc 162600 gggctgtttc ctgtcttttg gatgttttgt ttgtatagat attttcattt tatgttacat 162660 catttgttct ttggtagcaa aaattgagtt gaaatgatac agttcctgaa atctatgatt 162720 tcatgtttcg gagatatgta tcaggaataa tagtgtgggt tctcatgaga aaatctggat 162780 tgcattactg tgctactttg gtttcttgtc agagaagtta gtagtttaga cctccttcag 162840 aatcctttct ttggactttg tgtttcttac gttgtgccag ccttgatttt atttgtctgt 162900 cctctgtctt tctataccat ttgtttacac ttaactctag aattttttga tgcatgtttt 162960 cagtgtactc tagtcctaaa attggtttac atttaattat tggggagaat agcaagttgt 163020 cgatagtatc tgtggtggca ttagtgtatt tctgtttcag ttctttggac agtttgctag 163080 tggaaatagt cattgtattt agctctgtga gacccgactg gcagattgct gtctctctct 163140 ctctctctct ctctctctgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtatgc 163200 gcgcccgcgt ttgtttcctt catgtagatt gctgtgtgtg tctttttctt cataattccc 163260 cttaattctg tgtgctttga atgacactgt tgttgttact gttgttttat atccattgtc 163320 acataaaact cttatcattt attcttccag gccagggact gtccttatgg gtagagatac 163380 actatctgca ggaatttatt tttttacgta tttttactag ttgatgggaa agacattggg 163440 aaagacctgg gctggatttg tgatgagctg tgtttactga gcatgatgaa gtaaagctca 163500 acgtgattac tctgaagtcc agccttactg tcagtctaag gactcaggat acaaatactc 163560 aaaacataaa ttcttagact ctaaatttca catggttttt cctatcagta caggttaagg 163620 ataatggcgt gttgtaggtt tttccagtgc aatacaagga agttggttct agatccttta 163680 gtacagttaa tgttttgtag agtgtgttct atgttcactg cattggtatg tctcatcttt 163740 ggcatgatct tggctcaccg caacctccgc ctcttgcatt caagcacttc ttgtctcagc 163800 ctccagagta gctgggatta caagcatgtg ccaacatgcc cggctaattt ttgtatgctt 163860 ttgtggagac aggctttgcc atgtttgcca ggttggtctc taagtgatcc acccgcctca 163920 gccccacaaa gtgctgggat tacatgcgtg agccaccgta cccagccaca cctttgctta 163980 tttctactat gcatttcaag tgatcatttc aagagaataa gtacttagga gctcctatgc 164040 tctttttttt tttaaccctg ttgcttgcat cacccggttc caaccctata tgaaagtttc 164100 atgagcatgt ttctgtcact gaggcagctt ctccatttgg catataattg agaaattgct 164160 agtttgtggc tgagacattg gtttgagagg agacgtaatt tatatattta gcagaatgct 164220 taagttacat ttccagagat taatttaatt ctacttttaa ttaagttaac cctttgctgt 164280 atctttacaa gacgtaggtg gagatttaat tttgactctt agattcagtt aaggtgatga 164340 aattggcatt atatagtttt tgatgctgag ccccacggag attaaaagat ttgctaaaca 164400 ccatgcaatt tttgaatcac atctctaatc tcacattatt ctgtactcta ttttttgctt 164460 gtatgattga tgggtctttc attatctgtg attgacattc tatgagtagg tgcttttgct 164520 ttgcctataa gtcgttatta tgaaggagga atggtgaata agaaggtaat ttagaaaagc 164580 ctatattaaa tataccatga acattgaata tagcaagatc ttattctcta gttgttatct 164640 tagttgataa attctgtatg tgttatgtgt ttgtgtatac atatgtacat attaatgatg 164700 tgggtgttga tactgtgatc acatgacaaa tgactggttt atagtgaaaa gctgttgggg 164760 ttcagagaaa tgaacattct tctaaaagtg aggtagataa gttattttat agttcttgcc 164820 tttgagtctc tgttcttctg gtagaaatgt tagtgtattt ataacctctc agatttgttt 164880 ggttctctta gtgttcttga tccaggcagt tagcgatatg ttggatgaat tgagaaaaat 164940 gagtttttcc tttcctacta actgaattag attagaaata agcagttaag tgagaaaaat 165000 agggaattag tgccagatat gttgaggtgt agtgttgaca gggggtcttt taccttcaga 165060 tgtttggtgc aacttagaga atgcagtggt agttgctggc ccagcccatc caaacaacct 165120 catttgtggg gtgatacttc acagatgact taaaataaat cccctgaaaa taagaatctc 165180 tggaagagat gacacgtgta tgtgcgtgtg tgcacgtgtg tgcgtgtgtg cacgtgtgtg 165240 tgtgtgtgtg ttttggtgga gtggtaggag gagggttggc ttaatgatga gaatcattat 165300 ttcttgaatt ggatgacact ttccattcct gcaaagggag cgtgaggtcc agccttgcta 165360 attcatgatc aaagtaattt gctgagagta gtggaaggaa tgagttagca gaagatggca 165420 aattgcatta atgagtagta ggaggaaaac aaataagcaa attttaatgt ggttggaaca 165480 tgttcctgag ttgtatgaag ggagacaggt aaattgagag taatgttatg attgtttcat 165540 ttgttggaaa taaggaaaac ttgcatggtt tgaattgtgg aacaataggt ggtgtatgtt 165600 aggagtcaga attatcattt aacatgtaag tttctgtttt acttcagata aagaatgtca 165660 gctacctttc ccatgttagc ttctatacct tttcttgagg tgaccataaa taggtaatat 165720 tgtctttcac tgagattgtt ttaattagcg aagtgtgctg attaaatgtc ttttcttgat 165780 aaattattag aatgaataaa ggatggtatt tctagatagc cttggttagt cagtgatttg 165840 tttaaattta gtgtggataa gaatcacctg agggcttttt aaacacagtt tactgggtcc 165900 tgaccttagt gtttctggct tattaggtat aagtatgaga agttgatttt tatcaagttt 165960 ctagatgcta cagatctagg aaccatactt agagtgctat tatatgtctt ttaatgtaca 166020 ctgatatgga aaaagcaatg atacatcatg ttatcgcata ttttaaaatg tgatcatgac 166080 cagggaatct tgaaagttgt cttatgtaat aatgtaaatc aatgtagaat accatatatt 166140 tttttcttgc aaggttatta ttaataggaa tgactatttg tagccaatgt gttcaaatgc 166200 atgggaggac gtaaacactt cataatttcc tggaaataca gacatatatc acttaaaata 166260 atacatttct aatataaatt taaattatct acgtgatatg aggaaacgag cttatttttg 166320 ataattttcc tagcagtgaa tcaactatac tcatttgaat ctaaattaaa ttaaatttga 166380 gtaaattcag ccatttctaa attcagtcca tataaattca ctttgggtaa aagaagacaa 166440 aattcctgaa aacagtagat taaaaaaata acattttaag agcaggtatg atctcaatga 166500 atatagtgtg gtaatttctg cctaatacct acccttttgg aggaaggaaa ggtaatcctg 166560 tttgtgttta atgttaatta ctgaactctt tataacttgt tttatttatt tattgtttga 166620 ttttaagcat ctgcttctgg tggacttaca tatgttgggt ttgggaaatt tcaacataca 166680 ggttggcatt ccagtggcta tagttgtttc ttgaaattta gtactgtttt ccaatgatga 166740 ttctctttgg gaataggctg ttctctttta cttaaaaact gtaaaattag ccacttcagt 166800 tgagactcct ccaggtttgg aagtggtgaa gaatatggat atattcagat caaatcagtc 166860 attctctgtg atacagcaac tgaacaagaa acccagactt caaacaagca gacttctttg 166920 ggttggactg aataaaatga gaagaaatta cagaggattt gaaaatgtat atggcctagg 166980 aattattgaa attattttgg agggtggcaa caaatttggg acattgtact ttctgtttta 167040 atgtcaattg tataatgtgt aactctagtg agcatggctg gataccgtgg cttcacattt 167100 taggtagact gggtgtttta tctactgagt gaattacagc cttcggcaat gatgtcaagg 167160 tagcaacaaa acccaaaaaa tccatccttt agaaattgtt ttaagtcaca atgatgatac 167220 cttctttaaa agctttgact tactgaaata atgcttttca tttgtccaag atgagtacat 167280 agcagaattt ggaaatatgg ttccaaaagg ctaaatagac tgactttttt gatatttttc 167340 ccttataggg agaaagaaac attaacggtt tatcagatgc cttgactgta ctttttactg 167400 ctttgtcttc aaggcctagt gtaataatta acatctagta tgtgtttgat ggatagccaa 167460 tttttgcttc attggtatgt tgttaccaca gtcattggta gagtcaatat atgaatgaag 167520 aaagtataac aaatttgccc tctagtagag tacaggcaaa gtatggccgt cagtttcacc 167580 ctgatttttt ttcctccatt cttttttagg gtttaggtca agaacaaggg catttcattg 167640 taccacatag ctgagagtag ggaattggga catactgtct tgctttaaat taaagttgtc 167700 tgtttcatca agtagagagg ttcctaagat attgccagat ttctgactcg gggtttgtta 167760 aaaatagaaa aggtagttcc ttaaggttgt attttattgg atgcctccac ctgcttcagg 167820 ctagctcact ggagaataaa tattccaggt taaaaaaaaa aaagcatgtg ttcacgtgaa 167880 cttgtccttt gagcaaacct gttggaaatc aagaggtcat tgctgttgga gaggataaga 167940 gggtgtactt gttggtgtgt taagagtagt tcacaacata aaaataaatg taaatgcatc 168000 tattatattt gggttggcaa aatatattgg ttatttactc tgttgattcc tgtagtgtac 168060 ataaatatga tctacaactc tgtgaacaaa aaggcttgaa aaattgttct gaaaatggac 168120 aaatcatgaa cagataattg aacaagaaaa taagcagaaa gtaaatttgt gaaatatttc 168180 aaactcattt acattcagaa acatcttttt aagatcactg tgatacattc gactgtcaat 168240 tctgaagaga cgtataaagg aaatgccagc taaggagcaa ggaaacagct ttcattcatg 168300 ggctaaattg cagcttaaaa aagatggacc aggattattt cctttagaaa cttactgtac 168360 aaaagatact gttcacccca ttagagaact gatttgaagt tactcttccc tgtgagggct 168420 ctgtcatctt aactgtattc acatactttc aactgttccc cttgctgcta acctcaggtt 168480 ctttagttca tctatctggc agagctgatt tggggaaaac aagacaaacc ttctcaggtt 168540 ttcttaataa ataagcagtt gtcatgtttc aagagtttta gaaatgagca ataatcaagg 168600 aagaggacaa cgattgcata cgtttataat atttagaaca tcttttgcca caataaacac 168660 tggaaaccac ccacttgtgg acaccaaaca tttggatttg tatattttgt ggcattccct 168720 cactctaatc ctctcatcct taaaaatttt cagaaatttt tgcagcaaca aacactgatt 168780 gcaacatatg atttagggta gatttatgaa ccattttttc actgaaatac atcaacagga 168840 gtgagtagtc tgagtgacca ccccagcatg gagaaaactg tagtttacag attcttctgg 168900 agcattttta tttctagatt gcggtggaag tctaaccccc cttggagatg tctgccttaa 168960 agggtctttg gccagggtcc tctgtagagc catagtccag atctactcta tttgtgtgct 169020 ccttacaaca tcagaacagc aactctcaat ccggattcat ccccagaatg ccgtctgagt 169080 cacagcgtgg caggtgcata aagaattatc tactgaattg agaaacattt caaatatata 169140 aaacttgaaa tattttgggt agtctgtaca aactcaagtt gacaagccaa ccctgcagga 169200 atatatggat agaaggggaa ggataacatg ttgaattcag ctacatgcct catcagctag 169260 aaaaccttgg aagaaagaaa gatagattga tacttgcctg aacttcatca accaataata 169320 ttttttttct tgctatggag agtccactcg cctttggaag atttaccagt aaaagccctg 169380 cacatgatat acttgtgtgc acatgcaata aggacatcat tccccaactc ctgctagcat 169440 tgtgaaagag ctccaaatat tcaaataata taaacttttt ttcgtggaca tttagcttac 169500 gagtttgttt aaatatgtgg gaaaattatg tttagataat agtattgaaa tgagaatgta 169560 agatacacat tgaatgataa atgtgtatga attgttcatt gtgccttagg taagccagac 169620 agtgaaatta aatgtgtaat agttgtattt ttttgcataa tcttggaatg taattagtta 169680 aaagcaaaca cttagatttt gaacatgaat ctgttaagct tgttaatgta gttgctgtgg 169740 ctaaataact ggtttcctgg ggaagcttct atttgctaga attttattct ggaacagttg 169800 ttagaaagga attctcaggt caccttttaa agatatacac aattctgtat tcactttttg 169860 agtgcataag ggtaatagaa aatgacatgg gaagcgttaa ttagaaaaaa aggcattttg 169920 tttatgtgca tttgaggata cagtgtttga agtttctaaa taattgtttt atgacatttt 169980 cttggtacat agatattgct aacaattagt ttgctgaagt atgtagaaac attttaagaa 170040 atgattttag aaatataatt gttaaagtac ctctgatgta tattaaaaat ccttttattt 170100 tggtttatat tgctatggat gtttttctgg gggaacttaa tgtatacaac ttctaactaa 170160 gaagttttat taatgctgct ttatgtatga aagtcatgga tgtggatgtt attttgtcag 170220 tggtctttct gttaaaattt acgtggtgta agattttctt ttcatgatgg aattgccaaa 170280 aaggccagcc tctagaacac ttacatgtta agggttgggt gggatttgta ttactttgtg 170340 tatataaccg acaggattgt gttactgaat cttaaccagc atagagatgg ctgacatttt 170400 gcattttggg ggacattaaa ttgttacaca atgatgtcat tggttactga taggagtgtt 170460 tagactctta gatggctttg ttagtattag gcaaatatta gatgtggatt taggagataa 170520 gagggtgggg tgttggagcc ctgtgtgcac atgagcatat gttgcagggc ctccagacct 170580 aaatccacgt gaagatggtg gtggtggtct tacctatatg ttaacattac attgtaaaca 170640 ggtagactac tttccttttg ctagtgggag tgttaaatca cctctcagaa cattaattca 170700 ttaaattgcc cctaaacatt aattgattgc tggtggatat gctaaatatt tttaacatct 170760 atttttctaa atgtatagat gtcattttta attcataggg gatagaacca gttttgcttg 170820 caaaaagcaa actgttcact ggatcattgg gcttaatttt taggttgtgg tagatataat 170880 agaaatgttc ttacaatttg tagtataata ctgtatatct ctataaatat atatgtgact 170940 gtttttctga tagatgcaac atggtggaaa tgtcatcata aatgtcggtc tgcctttgtt 171000 tatagttttc agatgtgtat atgcagtttt ttatacaaca gaaaaattgc cacatgagtc 171060 aaatagcata ggttagaaaa gttctcattt gccaaaaata tgtgactttc ataatagtga 171120 gttgtttttg atttaaaatg tttctatctg tagaggcatt ttataagttt ttatggggat 171180 actagcaatg ggatgtgaaa cctgagttca ttagatcatt gggtgataat ggaaccctta 171240 tgtgtataca atatacatgg ttatatgttt tttaaagcat aggagctatt atgtctgcat 171300 ggttctaaat atatatacac acacgtaaac acatatctat atatctatct atatagatag 171360 atagataaat acatacatat gtagtgaaag cttttgtttc ctccctcaca taggcagatt 171420 atttgtgtgt gtaaatgagc agctgaaggg gaattttgtt acatgtgtat aagacagtca 171480 caatatataa ttgttttgct ttaattgttt agtctttgat ttgtaggaat tgccaacacg 171540 tatatttgtg tgtatgcagg tttatatata aatacatatc actgtataaa caacatttat 171600 tgtcatagga tagaaatatt cttaagttgc cagagatact gtatggctgc taaatgtata 171660 gtagaaaaat gttacctttt gctttttagc atctgcatac agattactaa taggcgtata 171720 ttgtgaccag taaaccacta gacaagggca taaacacttt agtttgatca gtagaattgc 171780 tatgccatgt ttaaatggga tttatttggt tgatgcagaa tatataattg tatctagaag 171840 ataaatatta caaaaatatt ttaatataca atttctgtca tatttttgga aatatatttt 171900 tattcaaaag tagaatcatt gttgccaata gagttagcat ctttgtgtgc ttgtgaggtt 171960 tgattttgag ggttttcttg gttttgtttt gggttctgga gttctaaaaa atgagattgt 172020 ctttgtctaa acaattttta tataaaaatg tacatttttg tattattttt tcttattcca 172080 acctaatcgg tggcttgtcc cttcctgtgt ttattgggct gttgggtgcc tggatagagc 172140 tggagaccat ttaactgctg tatgaataat agataagcgt cttgaataac atctgaattt 172200 cctaggtatg tagaaacacc caccatgcac atatatgaac atacagaata tatgaatgtt 172260 aaaatatggt gaaaacaatc ttttgctaat agaagtgtta acctttattt ttaaaaaaaa 172320 tttggtgtgt atgtagaggt ttatttgatt gttagttgtg tccatgtata atatgtcatc 172380 tacctttaca gatgtgcaga aatttgttgt atttggtgga tatattttac ttaaaactat 172440 agggcagaag ctttttatgt ttgttgaagt gaaatggcat accaaacctg tgtggtagag 172500 tgggattttt agattgctgt gtgtacagtc aggttatatc tttaaaatac ctattcgtta 172560 tatattaata tgtagacatt gctgatacat atgtatgtaa aaatcagagt atttttatta 172620 atataggcat tagcttcttg attcacttgt ttgttgggaa gcacttggag aaggatgttg 172680 aatactttgt catttcatct ctgtgacgta cagttgtcat gtcaaccctc ctatctgcgg 172740 gttttgcatc tgcaagcaca tgcagctgga aagtacagca ttggcagaat ctgaaacccg 172800 agtaaagagc acctcatttt cataaccatg ggttctgaag agctaaggga gttgaggatg 172860 caccgatttt ggtatggggg tacggtacag gtacaaatcc ccgatggata tcactagaca 172920 actgtacaat cctctttagc tttttttttg ttttatagac agtgtggacg tgcatatatt 172980 gcaagcatca ctttgttaaa ctatgcttaa ccctgcaaat gattttaaga gctctgtgtg 173040 ggtggctttc ttgggtttac tattaaatat ctgtgtttat catagttgtt ctataacatt 173100 tcaactttgt aaatatgtag tttgttgata aagaggatag agacattttt cttttgttga 173160 tagattgttc tttccccttt gcttagtctt cattgtgttg ctgggattgt aaaagacaaa 173220 ttacttgcac atatttaagc ttatatatta aatgtatata tgctgtcatg ttagagaggg 173280 agagtggttc cctcccccac attttgattt aaaagtaaaa attaattttt attaaattgt 173340 ttgggtcagt ttcatgtaag aataatctct acattgaatg gtatatcttg gccgggtgcg 173400 gaggctcacg cctgtaatcc cagcactttg ggaggccgaa ggggccagat cacgaggtca 173460 ggagttcgaa accagcctgg ccaatatggt gaaaccccgt ctctactaaa aatacaaaaa 173520 ctagccggcc gtggtagtgc acatctgtaa tcccagctac tcggcagtct gaggcagaag 173580 aatagcttga acccaggagg cagaagttgc agtgagccaa gatcgcgcca ctgcactcca 173640 gcctgggcga cagagtgaga ctccctctca aaaaaaaaaa ggtatatctt attttctttg 173700 atgtactgag gttcatgatg caattcattc ttaagcatat actatagaat ctttaaatta 173760 tatggttctg tgttcatttg tggcatgaca gtaaccaaga caatttagta aataatcagc 173820 aaatgaaata tttaattttg aacatctagt atttctagat gtatagagag tctcacgaag 173880 tagatttttt aagtatcttg ttgtaaattt gttagtactg ttgtcttttg caattaatgt 173940 ggcaatgaaa ttgattattg atacacaggc tcttggagct aaacaaaatt tatcgtgttt 174000 taatttggat attagaagga ggaaatgaaa agagactctc tacattttac ctgttattat 174060 atagcttacc attatatcag atatgaattg ctttttttaa aaaacttaga ttaaatgtca 174120 tgtaaatgca tttagtcttt ccagatacac ttcttgatat cataattttt atttcctgtt 174180 aatattcaag atataaatga cttcattaaa gagattttct actacctcta ggaactatac 174240 aatattctgt atgtgttccc ttggttgcat gacaatattc aagacaactt tgtaaataat 174300 agataaaaaa ttttaatttt taacatctag tctttctaga tgtatagagt ctcacaaagt 174360 ataattttgt aaataagtca ttgtaaaatt tcatggtttc attgtgtttt gcaaatgtct 174420 tggcaaagaa cttgataaaa ttttgggctt cttgacctat acatattttg gtatctcttt 174480 attgggttgt ttagtgtaag gaaaaagttg aaagaatgta ttttcaactt tgaattgtaa 174540 tcagaaagaa aatatatttt aaccattgtt tagtgcttct gttatatatt gaaaacttca 174600 gtcttaattt tttagttaca ttgttgatag ggcattatat aaatatactt ctatagtcat 174660 tgtaggaaat gtcttttata aggaaatatt tcttctacct ctgaattaca cagttttgta 174720 tttacttgga ctgcatggca acattcaaaa aacactttga ataacagata aaaatgacat 174780 tttctaaagc tctaggtttg ctagatgcat gaagtctcag caaagtataa atttgtaaat 174840 atttcattgt aaaatatcat aaattgactc cttcaagtgt tcagtagtac aataggtaat 174900 caataattgg cctcttggga ctgactgtaa cgttttggtg tttgtatgtt ttgagacaga 174960 gcaatagatt gcctccatat cttttaaaca ttcaggtctc ttgtataaga aaaataacca 175020 ttgtggggtt tttgtgcatc ttatactaat atgaaacaaa caaaaccccc tggatatttt 175080 atccttagaa agatagagga agacaggaga agggaatggt cattgtaaat tagatagata 175140 tattgagtgt tagaagatta tttaaataat tgttcttttg ttatttgtac tctttgcaaa 175200 tttatttaaa tgcatattca tgtatatcat aagtatatat tcacatgcat gtctaaattt 175260 agtggcatag atctatctca ggggtattaa tctttcattc gtgtactgat ttgtgtttta 175320 ttttcattta aaaaattgtg gaaccagtgg ctgggcatgg tggctcatgc ctgtaatccc 175380 agcactttgg gaggctgagg cgggtggatc acctgagggt caggagttcg agaccagcct 175440 ggccaacatg gtgaaccccc ccgtctctac taaaactaca aaaattagct gggcatggtg 175500 gtagatgcct gtaatcccag ctactcggga ggctgagaca ggagaattgc ttgaaccctg 175560 gaggtggagg ttgcagtgag ccgagattgc accattgcac tccaccctag gcaacaagag 175620 caaaactctg tataaaaaaa aaaattaaaa aaattgtgga actagtgttt tatttctaag 175680 cttgcagata tttctagaat tccacttact gttacatcta aatgtatgct gatttttcgt 175740 taaataataa gcaggtctgt aaacattttc ttttctaacc tctttccata tttatatgag 175800 tatagaaaaa ctgtggttat gaatattttt tactttttga taacttttaa aaactatcag 175860 atatgtgata atcagataga tttcaagttt acttacggtg taaattagga aaatttttat 175920 aaagattcta tccagtattg atcaaaagta taaattgtgt gtctttttaa gcagcagttt 175980 ggcaatgaca atcaaattga tactatgtaa aagttttgaa atgttatagc tggctactgg 176040 ggtttttatc tattccagtt ctcgaaaatt taccaaatat aggttggctg taaaatcata 176100 actatctgag gtatctgtca ataaatcaaa gattgcaatg atgatagctt ctttaacatg 176160 aatgtaattc taacagtaaa aaatttctat atggaatatg ttttgtagtc ctaaattgat 176220 attttatatc atttttcagt gaacaagtag ttgtttacag gtgtctgtgc atatgtctca 176280 agtttttcta actaaaatat taatagttaa gtctaaaaat atgaattata cgtggggctt 176340 gtcattctga catttaatac ttcagcgtgg tgataatggt gatataatat actgtttgaa 176400 attgtaacac atgagttaaa atcaaaagat tgataagtac atatttgtat attgctacat 176460 gacaaaaatc taggaagaat atgattcaca tgaaaattct ttggaaggac atgacagact 176520 tttaacagtc ctgtatagtg aaaggagaat agaacgacta cttctacttt ctgtatctga 176580 aattttcaaa agctatttca aaatgaacat ttaaacaaca ggaaatttta gagacaacca 176640 ctttgtgcct gtcttcatcc ttgacattca acatcctagg aacaatgggc tgttgtattc 176700 aacttcttat tcccaacagc cattatgaat ggtttttgat tgatctcaca aagagcatgt 176760 gctttagaca ttaatgcagc gactaccatg aaacagagta ttggattacc taaggaaaga 176820 agcagaggat ggaatttgag gtaggtgtca aacagtgaaa tttcgtttga gaaacagatg 176880 agtgaaagaa aatagtaact gaaacattca ttctataagg agagtacatt ttaatactgg 176940 cgatgctgta tttgtgggta ctgactagat caagatgtta gaggaggtgt ctcttgggat 177000 aagttggaag ttatccttca ttaatttggt ataaactgaa aacagattgc ttctttcctt 177060 ttaaagtggt tgagtctctg atgggtttaa agtaggcctt tggggattta tagatcattc 177120 aaaattagca ggggaaattt taaatattct ctgcatcttt ctaaaaggtg tggtttaaag 177180 ttggtgagaa agtgaaatgg ttgctggttg aacttgattt tctctattca ctatgcctgg 177240 ctagcctaaa attatcctaa tgggtatgtt caggtgcctg atttgtatct aaatgtttct 177300 gtattggata ctgtttttct taggcaatca ggatgagtga aaaattgatt tgcagctgac 177360 ctgcaaatgg aatcatcagg aacatccctt tctcatggag tcccttaatt tacaagttaa 177420 ctgcaaacat aggtaagaag gttctggtgc tatttggggg tgaggtattg gtgaggtttt 177480 gcctaagctc aggaaaataa tactggtaca ggtgtatttc ttggccacct tggaattatc 177540 aaatgagtta gtctttaaaa tatattttat cgaagtgaag gtatagtttg gttcccagac 177600 caaactgagg gtcgggctgc tatttctcgt gccccaataa tgagatgcag atgaacaggg 177660 gaggaagagt tagagctagt tacaggaaga aggcctggaa attgtcacca caccaactca 177720 aaattacaaa gtttttcaga acttatatac cttctaagct atatgtgtac atgtaagtgt 177780 gtatctaaag acataagtga tctataacta aggtctgagt cttcgagacc ttcctttgga 177840 gcctcagtaa atttacatta atttaaatgg gtctgggtgc tgaggtgatt accattatct 177900 tgtttcctac taaatcatgg aggtttgggg agttccttta gaacccccaa taaacttgtt 177960 tgtggaggcc tggagagttt cttcagaccc ctaataaaac ttgtttaatc gtgctttaag 178020 gttcaagaga ggcctaggta aaacttggtg ggcttttgtg acattccaac ctttgtataa 178080 caaaatggct ctttcagctt ttagtattta acttaaccac tccgtcaata ctgaaacagt 178140 tgttatggag gcctccatta gagggacctg gcctgccaca ggtgcgcgcg cacacacaga 178200 tgagagtacc tttaattagt ttacttatct atggtcaaac acgacaatat aactaataaa 178260 agaaatgacc aggcatctaa ttactagaaa ttataaaatt gacaatatgt gtgttttcat 178320 aaatgtacag ttttcacaaa atgttttcac atacagttct ttgataaagg gtgaagttca 178380 tggaaaccac agaaagatgc tgatactgta aactattaaa gtcattactg aggttgtaag 178440 ttgactttgc tataggattg ataatgggaa gtgtttctaa atgttaacat aacctgtaat 178500 aaagttcaac atgagcattc acttaacctg ccgccttagc tgtttcatta gagtggtata 178560 tatctcacct tacagtgttt cttctttttc cttgtcagga gatgatagtt ccaagaagga 178620 acattttatc gtctttgttt ttaatctcaa gaatggtacc taccatcagt gaatgacctg 178680 ttgcagtgct ttcattgaag tgttcttcgt tccctcagca atatgattgt aagggcagtt 178740 gagtgctaac ttgactggga gaggggcggt ttggttagac aggacttgat atattctgtt 178800 tttcataagc ttgatgtttt tttctggcag ctacttgaca ttcagatctg attggttaca 178860 tattgctatg taataaatta tcctgaaaca ggggcataaa caatattgtt atgtccatgg 178920 attctgttgg tctgaccatg cccaggacag tttaggaatt gtatcctctc caaagtttca 178980 ttgtagcttc tgtgttttta gtatagttac tatttctttc tcatcaaata gactgaactc 179040 cttttgttat tatcatttaa atatttaggc attgttgtca tgtatattgt gcataaatgc 179100 atgtatactg caggtaataa ttctgtatgt gaacaagtga cctagaggta aaggaatcca 179160 aatacagaga cgtgtggata atgtgggaga ggtcagtttt tcacaagaca taggaaagag 179220 gctgggcgcg gtggctcctg cctgtaatcc cagcacgagg ccgaggtggg tgtgtcggtc 179280 acttgaggtc aagagttcaa gaacagcctg accaacatgg tgaaaccccg tctctactaa 179340 gaatacaaaa ttagctgggt gtggtagtgt aatcccagct acttgggagg ctgaggcagg 179400 agaatcgctt gaacccggga ggtgaagatt gcagtgagcc aagatcacac cattgcactc 179460 cagcctgggc aacaagagtg aaactccatc tcaagaaaaa caaacaacaa caacaacaaa 179520 aaagaaggaa agagctaaca tctgacctcc tttattatta gaatactcca aaaggaattt 179580 tgatccacat gctctttctt cataatagaa tgaatgttgc atgtcatttt acagacaaat 179640 tttattagtt cttgctgatg atataaactt tgcttctaac cttttcccat tttcccaact 179700 gtgtctctca ggtgatgact gaaaaaggga aactgtgcca ctatttgtac catcattttc 179760 accaaaatct aaaaatgctt tttatgacgt atggagacat tcttcatgtt tgtttcagtg 179820 gacactcctt gcagatgtaa aaaactgaga aaactcactt ttggaaagtg acctaaagag 179880 tgtcattgaa gtgaatttta agtaggcacg atgattgttt tcatggttgc tgttggatca 179940 tatctcagga gctggaatga cagacattat tgaacaaaga aatcaggata gtggaactta 180000 aagggcttca tctcagtgct ttcataagta tgaagtgcat atatttataa ttttcactaa 180060 tcacagggta aatataaaat tgattcatta aaaatgtttc ataagaattc aaaggacata 180120 gaattttgtg aaatgtagta tttttactta agtgcctttt ctctgcttct accccacagc 180180 caatttttta taaaccagtt gataacataa gtagtttttg ggggatgata cattacttat 180240 acattttcta tgtagtaaac atgtatgtgt atgtgtgtgg gtgtgtgtct aattactttg 180300 ttggacagat tcctgtggtt tggaactgct ggggccaagt ttatacaaaa atctacattt 180360 ttgagtaaac tccccatgac tctagtaagt ttccacagta tttgagtatt ctttatttcc 180420 taaagctgta caaacatcag ataatcaata tttgtaagga tcgataatat aatttataat 180480 gaaattgctt tatcagctat taatgttaac tacatcatct tcatatagcc ttataactca 180540 tttgtgctat tccattttcc tctgttcctt ttattttcac ttcccttgta atgttagtct 180600 ctttgtactg atttctgaag agttcattta tgattaaaca tgttaacatt ttgtctagaa 180660 ttgcaaatat gttttttctc attcatttta ctatggtgtt ttattttttg gttatacaga 180720 agttgtatat tgaaatataa tcttgttctg ttttatgact ttggagtttt gtggtttttt 180780 aaaacatgtt tacattggta tcatttattt gtattgcctt ctatttcagc agttagtttg 180840 tcatttcttt ttccattaat catcattctg gtgttaatga atgcattaaa tatttaaagt 180900 actcactttg acccgtgtag ttatctgtta agttctacca taaagaaaat ttccaggtaa 180960 aattggctac atttctgtta acttgcctta ccattttatt gacactttaa taattactaa 181020 tgatttatac tgtcttatct attccattga gttctatctc atttctcttc tttttcagaa 181080 tattccctct gtatacttgc atttttttct atcaattgac gcttacaatt atttttgcaa 181140 gttggaaaaa aatgcagtat taatttcatt tgcaacaaat ttaatagatt aattaggaga 181200 gaatagatat ctttaaaatt gagtcttctg tccaactgca aggtaggtct ttctattttt 181260 aatggaataa taatttgggg atattgctag tgcagttttt taaagtattt tttaatacta 181320 ggcatttttt agttatttgt taatttagtg atttggatta gtcattcaac ttgtctaatt 181380 ggtatgtgaa aactttttgt atgtcttttc tagtaatctt tactgaattt ctaaaattat 181440 gactttcttg aacaatctgt cattttaatt accttgatta aagtacattt gtaagtactt 181500 ctaggatata tggaagtaga aagtatactt ggcaattgga ctgttaattg caatcccctt 181560 aggtcatggt tgtttttgtt cttattggta ttttagtaat cttttagaag aaagatgttt 181620 taccaaattt ggtgacaggt ttaataaaat ttctttttgt atagttgaaa aacttgtcct 181680 tataattatt aaggttaaaa ttaacatatt ccaaaattga acattattcc atcccatgaa 181740 tgaagtaaat tatattttag tatatactcc ttaattatag ttgttataat ttcatttgga 181800 atttctgaaa tgattcctaa acaaacagct ttatacttgt tctgttatca gaggttttta 181860 atgttttact ggctctttga aaccattttg agtatttctg acacagacta gaaacaagta 181920 atatttttct ttaattattt tgaaatgttg gcttaaaaag gtgttgaaat aatagcgtgt 181980 tttttttttt aaagttattt atcttttgtc caaaatcaac taagcattta tgcaagcatg 182040 tgttttttgg aacccttttt tctgtttcct tgttctttgt gtttttcttt atgccaatat 182100 cacactgttt tgataattgt agctttgtag ttaacatttt gaaattgaga actgtgactc 182160 ttccaccttt gttctttttc aggtttattt tgctcatttc agtcctttga aactctgtat 182220 gagttttagg attttttttt taatttttgc aaaaaatgtc atgggaagtt tactagggat 182280 tgagtctgca cattgcatga gtattattga cataaacaat actaactctt ccagtccatg 182340 aacatgggat gtctttttat ttatgtcatt tatttctttc agaaatggtt tgtaaatttc 182400 attgtacaaa aaattttctt tgatcttact ggttaagtta ctttctaagt attgtatttt 182460 taaaatgcta ttgcaagtgg aattgttctt tgaacttctt ttgtgaattg ttcattgcta 182520 tttttgcatg ctgaatttgt agcctggtat tttgtggaat ttatcagttc tgagattttt 182580 ttttatgctc ccaaggaaaa ttttagcccg taataatttt tttggagaca tagtctcact 182640 gttgcccagg ctggagtgca atggcactat ctcccaggtt tgaacaattc tcctgcctca 182700 gcctcctgag taggtgggat tacacgtgtc tgccaccacg cctggctaat ttttgtgttt 182760 ttagtagaga tggggtttca tcgtgttggc caggctggtc tcgaactcct gagctcaagt 182820 gatcctcctc ccttggcctc caaaagtgct gcaattacag gtgtgagtca ctgtgcccga 182880 ccagcctata aaattttagt ggatgccaag agagatactt ctacttcttt tctgacttgg 182940 gtgtcatttc tttctttttg ttacttgatt gctgtggcaa ggatttgtaa tactgtgttg 183000 aaaagaagtg gcgaaagcag gcatccttgc ttttgtaact gatactagag gaaatccttt 183060 tagtgtttaa cctttgagaa taatgtttgt tttgagtttt tcatttatag cttttactat 183120 ggtgatgtga tttcatctat tcctaatttg atgaatgttg aattttttat tccttagtct 183180 ttgtcttgct ttggtaagag ggtaatgctg gccccataaa atgtgttggg gagtgtttcc 183240 tccttgaatt tcttagaaaa gtttgaaaac acttgttatt tgttatataa gtatttattt 183300 gatggaagat tttttttttt tttttttttg agactgagtc acgctctgtc gccccaggct 183360 ggagtgcagt ggcgcgatct ctgctcactg caagctccac ctcccgggtt cacgccattc 183420 tcctgcctca gcctcccaag tagctgggac tacaggtgcc cgccaccaca cccggctaat 183480 tttgtgtata ttaagtagag atggggtttc accatgttag gcaggatggt ctcgatctcc 183540 tgaccttgtg attcgcccgc ctcagcctcc cagagtgctg ggtttacagg tgtgagccac 183600 tgcgcctgac cggaagattt ttcattaata attcagtact gttaatagtt tcatgcgtgt 183660 ggttttgttt tggtggcctt tagtttccta ggtttgtagg aatttgtaca tttcatctag 183720 attatctaat tttttaacat tcacttgctt atagtactct tacaatctct tagttctgta 183780 gactttatgt ttctgatggt agcaatttga gtctgccctc tttttttcta gtccacttag 183840 ctgaagcttt gtcagttttc ttgatttttg tttatgaaga accaagtggt tattttgtgt 183900 tcattttctg ttttattcat ctctatatca ttctttatgt ccttcctttt cctctttgtg 183960 tttactttgc ttgtgtaatt ctttaatttg tacagttggt tgatttgaaa ttttttttca 184020 tgttacatta ataggtgtaa gattcataag aaaacatgtt ttattttcat tttcattcat 184080 tcccacatat tttctaattt tccttataac ctcttggtgt actagttgtt tgtgttttct 184140 catgtccaca aatgtgtgac ttttccaagg ctttccttct gttactgatt tctaaattca 184200 ttgtcttgct gtggtcagag aagaggcttc tttttctgtc tgttttttca aaatttattg 184260 agactgaatt tgtgaattaa ctacatttgt tgtgaaaaat atctcatgca cttgaagggg 184320 agtgtgcatt ttgttgttca gagattgttg tgtgcatatc tgttagatat aattgattta 184380 ttgtgatatt acacacttct attttctctt tttttgtggg gtgaggggtg agacagagtc 184440 tggctctatc ccccaggctg gagtgcagtg gtgtgatctc ggctcactgc aacctctgcc 184500 tcccagattc aggcgagtct cctgcctcag cctcccaagt ggctgggatt acaggtgcct 184560 gccaccacac ctggttaatt tttgtatttt tggtagagac agggttttgc catgttggcc 184620 agggtggtct caaactcctg accttgtgat ccacctgcct cggcctccca aagtgctggg 184680 attacaggcg tgagccacca cacctggccc acacctctat tttcttgttt tctggttatt 184740 ctacccatca ttgagagtag gttcttgaag tctatatttc ttagtgagga aatgtctatt 184800 tctcccttct tttatgtcaa tttttgtttc atatattttg atggtttact aggatcataa 184860 atgttggtca tctttatctt gtaattttta ttaatgtata atgtacattt ttgtttgttg 184920 taacattttg gattaaaagt ctgttttgtc tgacttaagc agtctacaaa ataactgctt 184980 ctgtaacacc ttctctccta cccctttcag ttgatgctac aaaattatat gtttaacatt 185040 gtgtatcaaa atatatatat atatttgaga tggagtcttg ctctgtcacc caggctggag 185100 tgcagtggcg tgatctgggc tcactgcaag atccgcctcc agggttcatg ccattctcct 185160 tccttagcct cccgagtagc tgggactaca ggtgctcgcc accacgcctg gctaattttt 185220 ttgtattttt agtagagacg gggtttcacc atgttagcca ggatgatctt gatctcctga 185280 ccttgtgatc cgcccgcctc ggcctcccaa agtgctggga ttacaggctt gagccaccac 185340 acccggccca aaatatattt tgtaaaattt attttttgtt aaatttttta gaagataact 185400 tgtagagtta taatcaaagt tacaataata tttactggtt ttttgcctaa tgtgtggttt 185460 tataattgat caattcaagt catgtagaat ctaaaaaagg caacaggctg ggcatagtag 185520 ctcatgcctg taatacccag cactttggga ggctaaggaa ggaggattgc ttgagaccag 185580 gagtttgaga ccagcctgtg caacatagca agaggctgtc tctacaaaac aaattttaac 185640 aacaaaaaat agctgggtat ggtggcatat tcctgtagtc ccagatactc aggaagctga 185700 gatgcaaggg tctcttgatc cctgaaggtt gaggctacgg tgagccatga tgatgccact 185760 gcattttagc ctgtgcaaca gaatcagagc ctgtttcata atgaaaaaca agtggaggga 185820 cagtacacca ttattaacct ctcataattg ctcaattatt tacctttaac cacatcttta 185880 tttctttata gggcttccat ttactattta tttcaacctt caggagtctt ttcagtgttt 185940 ctgtttggtg ggggagcaga tctaatgtaa acaaactcct gttgtttgta catctgggaa 186000 cgtatcaatt tctcccttac tttttaatta acagttttgt tggatattag attcttagtt 186060 gagtattttt ttttttttag cacattgaat gtgtcagtcc actaccttct ggccttatga 186120 gaaattgact gataatccct gttacatgat atcgtttttc tattgttgct ttcagaattc 186180 tttctctttt gctcttcata gttgaaagat attgtgtctc attgtgggtc tttgagttca 186240 tcttgcttgg agtttgttga ggttcttaga tgttagaatt catgtctttc atcaaatttg 186300 agaagtttcc atctagaatt tcttcagata ttctttctat tgcatgcttt ctcttttctg 186360 ggaatcctgc atcgtttgta ttggttagct tgggtggtgg accagaagct gtttagactc 186420 ttacctttct tcaatatttt ttctttttgt tcctcagaat tgataaaatt ctgaagtttg 186480 ctgatctttt ttgttgcctg ctgagataat gcatttgaat ccctgtagaa aatttttcat 186540 ttcagttaat tgaatgtttc atgttccaga atttcatttg gggttccttt ttgaaagttt 186600 ttttattttt gattattgat ccttccattt tgctcatgca tcattttctt aaccttctct 186660 atcacttcct ttagttcttt gagcaacttt aagacagttg ttttaaaagc tgcttacctg 186720 tcttaccatc tttgagatca gaagtggtaa actgatgaga gcacagcctc tcaatgtttg 186780 tataacagag tggtgtgttt tgttttttgt ttatgcctac catcactcct tctgcaagct 186840 gtatgtaagt tgtccaagaa atgtgtacag ctaccttgcg tgagggtgta ggagttaggg 186900 ataggtaatt tgtactttgc taagagttga tgttgagtga aattaacctc aataaatctg 186960 aatttagggt taatacaatc ctccagagtt ccaaaccagt tatatcatac cgattattct 187020 ggtgtattta tcatctcagg gggagaaaga gttctgttgc gtcctgctct gccatactcc 187080 cagaatcctc agctcaccag ttttttagtt tgtttgtttt gtttttgtat ggatacagtt 187140 tctcattctg tctcccaggc tgtagtgcag tggcactatc atagctcact gcagcctcga 187200 cttgttgggc ccaagggacc ctcttgcctc agccttctga gtagctggga ctatggacat 187260 gcccgaataa tgtttctttt ttaaagagat ggggtcttac tacattgcat agcctcatct 187320 cggagttctg cactcaagca ttcccccagt ctcagcctca caacgtcctg ggattctagg 187380 cgtgagtcac tgtgcccagc ttgttttaca gtagtgaaat gaatctgccc atttatactt 187440 tctgattatc aatgaaagtt gtgttctata attttgttgc ttttcagttg tgatagttta 187500 tgcatcacat aaaatttgcc atattaacca gatttaattg tactactcat tagcattaaa 187560 tgcactcaca gtgttgtgta actaacacca tattcaaaac ttttgtcatc ttaattggaa 187620 actctatacc tgttactcta atccctagtc ccttgtctcc ccaatcatgt tttctgcatt 187680 tgattttgcc tattgtaggt atttcttaca agttgaatca catagcatgt gttttttggt 187740 tcctggccta ttttacctaa tgctttcaag tttcatgtaa tacatgagaa cttcatttct 187800 tattatgacc gagtaaatcc attttgtgta tgtatacatg tgtgtataca tgagtgtgtg 187860 tgtatacaca tataacacaa tttttatcca tctgctaatg gatagaattt taaatctatt 187920 cctctgctaa tggacatttt atatgccagt gctcaccaaa acattcacag tgtccattaa 187980 gagatgaata catttaaaaa tatgtccatt aatatttgag tgagcattgg catacaaata 188040 tctgagttca tgtcttcgta tctgattatg tatatagggg aatgaaattg ctgagttatg 188100 tggtaattta atgaactcac tttttgagga aatatttgtt atttattatg agaaattgaa 188160 gtcaccaaaa atgagaactg aataatgaac cttctcatat ctagcaacta gagttaataa 188220 ctatgaacat tttgccatat tttgaaaatt acagttacca tggtgattta atcctgaata 188280 ggtttatatt tttatgtatc aatttttaaa ataatcacaa tatcctatct ctacctagta 188340 aaatttacta aaatccctta tgtgtcttct aaacacacaa agaaaaaaca attctcattt 188400 aaatttctca aggttgtgca tggtgtctca agcctgcaat catagcattt ttggaggcca 188460 aggcattttg cttgagccca ggagttccag atgagcgtag gcaaatagtg aaacctgttt 188520 tcacaggaaa aaaaaaaaat gaggtatggt ggcatgcact tgtgaaccca attatttcag 188580 aagctgaagc aggaggatca cttaagcagt aggctacaat cacaacactg aactccaggc 188640 tgggtaacag agtgaaacat tggctcaaaa atataaaaaa ttctcagttg tgcgaatgat 188700 acaacagttt tttgagcaaa tctggatcca agtgagtaat tcacttttat ctaggctatt 188760 tttatgttag tcttgactgt attaatttat attcaatctt aaatctctct taattaaggt 188820 atgaaagtca accctttttt ggttctatat ttaagtaatt tttaaaaaaa tcttgaatta 188880 aaaacattat ttagaagtaa ctttcatatt ctactggatt tcttatttgc tggttttttt 188940 ggggggattg attctaccct ttatttttag tattctgaat gagttttggt gagctactgt 189000 ggtccaaaat atatattgtg tatacacaat acatagtctg aattcttgta taacaaaagt 189060 acagtccata tttgtaaggg gtgcttggaa aggtatatta ggtatattac cttacatgtg 189120 tagatcttca taagtaatag ttggcaaggt ctgctataaa cttgttacat atttctatat 189180 ttgtcattat attagagaca tttttagtct ttgatgttat ttttcccatt aatatggtgt 189240 cctgacctgg tcatgctttc agtttttcat gagatcatgc taatgaaatt tcttaaaagt 189300 tttgcaaata taatctgata acgtactttg attttttgaa aaaaagtcat ctcttaccca 189360 gtaaatatca actaattgct ggttttcttt tgtgatttct tctcaatgta ttttatatta 189420 aggtttggag ataccagtcc ttttaagcct aatcctcatg ctatctggta aaaattatta 189480 acaactaaaa attacttaat gtatattaca aaggaggtag taccatctat gaaatctttt 189540 tgataaatct tactccactc tgtcttatgt atgtttaaat gagcaccaga agaattatgc 189600 attacatttc atttgattgg ttaatctttg agctcttggt ttttaatatt tgtttcttgc 189660 tgttttctct ttgaggaaat gagttatttg cgatataaaa ctttcacatt tctacattgt 189720 gcccatagta ggatgccacc cctgtggtca tgtttaatag ttttttctca gtgtttcggt 189780 gtttaatatt ttctatcatt tttttaaaaa aatattcaac attgagacat ttttctcaat 189840 gtattatatt ctcaagatct gattttttgt ctgactagtt ttatcaaatc attaattcag 189900 ccatttatta tatgaacacc ttttgtaaaa cagaagaaca ctaatttatc atgatatttt 189960 catatatatt ttgtgatatt gagaatcatt aagtatttta tcacctgctt tttacaaaaa 190020 cacaatagtc tctcatttca ctaatagtta tacatttgct ctaagtatca gtaaatttac 190080 tctgaatgat aagttcttca tttaaatagg aacttaatca acttttttgg gatttcagtt 190140 caaaaggaaa ggtaaataaa tgttttttcc cttatcttac catttatata ataatgaatt 190200 gatgtgcaag taatcttcaa aggtgactag tttttaaatt catgttcttt attcagaaga 190260 cagaaagcat tttcaggaga tttgaatatt tgaagttata ttttaaaggt gataatgcta 190320 atagcataat taaaaaacag tttctgcatg taaacacatg gtagaatata acaggtaata 190380 tatatttgta attatttttc tatttcatgt ttattcaaat gtatgtacaa tctctgtagc 190440 ttgtagtttg gctgtgttat gctttataaa atttatttat ctgagacagg gtctcactct 190500 gtcgcccagg ctggagtgca gaggcatgat gtcagctcac agcctccacc tcccaggttc 190560 aagtgattct cctgcctcag cctcccaagt agctgggact acaggcgtgc accaccacat 190620 ctgactaatg tctatgtata tattttttag tagggtcagg ttttcaccat gttggccagg 190680 ctggtcttga actactgagc tcaagtgatt aacctgcctt ggcctctcat actactggaa 190740 ttataggcat gagcctccac acccggacat aacatttatt ttttatttta tattttatat 190800 tttatatttt attttatttt tgagatggag ttttgctctt gttgcacagg ctggagtgca 190860 atggcacgat ctcgcatcac cacaacctcc agctcccggt tgcaagcgat tctcctgccc 190920 agcctcccaa gcagctggga ttacagataa gtgccaccac gcccggctaa tttttttatt 190980 tttagtagag tcagagtttc gtatgttggt caggctagtc tcaaactcct gacctcaggt 191040 gatttgcccg cctcagcctc ccaaagtgtt aggattacag gcatgagcta ccacgcccgg 191100 cccataaaat ttatttttat cccagttgtg tgtacttatt tacttatgta tttatttata 191160 tttatttatt tgagatggag tctgactctc ttccccagac tggaatgcag tggcacaatc 191220 ttggctcact gtagcctctg acaccagggt tcaagccatc atcccacctc agcctcccaa 191280 gtagctggga ttttaagcat gtaccaccat gcccagctaa tttttatatt cttagtagag 191340 acagggtttc accatgttgg ccaggctggt cttgaactcc tgacctcagg tgatccacct 191400 gcctcggctt cccaaagtgc tagaattaga gaggtgtgag cctccataag gaatatgatt 191460 tgaagggaag aggggatatg agtgtgaggt aaatgttttc ctatttaaat attgaaatat 191520 aaaaggctat tcagtttcca ttcaagtaac atttggaagc tttttatttc ataatactat 191580 tttgtgtaga aaccattact gtttgttttg tatttgtgta ggtaaaaagt attatgaaat 191640 tatgtaatta cagtattcac tctgccaaaa aaaacaaaaa taattataac tcgggtatct 191700 aatgattgaa catttagtaa ttcttccctg acaaaaagag aaaaatatta taactcaggt 191760 atctaatgat tgaacattta gtaattcttc cctgattata aaagtagcac atttatactt 191820 tggaaaataa aacagcatgt atgggaaaaa gtaataaaca tagagaaatt ccatcacctc 191880 ccttcccctc tcctccaaga aaaagtggct tacgcctgta atccaagttc ttagggagcc 191940 agaggcagga ggatagcttg agcccaggag tttgggactt gcctgggcaa tatagcgaga 192000 ccctgtttcc ccaccccacc cccccaaaaa aagaaaaacg taattccata ttttacaggt 192060 ttagtgttga cttcataaaa gatggaaggg aaggttatca gagtatccca ttgtagtgat 192120 tatagtgctc agattctagc tccatacctg ttagaacaca ttcgcaattg tcagcttaaa 192180 ctatatttgt atgtattgtt tgtctgtttt gtattaaagg caaaagctca ttatcaatta 192240 gttgtatgtt ttaaagagtt ggccacaaca tccatcataa gacctatcta aagaggaata 192300 catgatgtct tagtacaaag gagtagagat acaatgaatg tatttatttt catgtttctt 192360 aagagggaat gcactagcaa ttgacggtaa aatagataca aatcaagtaa agaaaccagt 192420 atatttttag tcattatgtc gctttgaaca acaatttgtt taatcatttt gcggtaactg 192480 gttgcttgga actgccttat tttttgtatt caatatattt atttatggga gtgtatacat 192540 attccagggt gttctagttc ctcagggaaa atctggatga catagaagaa ttttgttctt 192600 tattatgagt caatttataa tttcatcttt ttttaaaagg catttttcct acagctagac 192660 gttttgattg tcacttttgt tgtgagaaaa aaattacaaa gacgttgtaa agattgggaa 192720 tgaggaaggt gacttgatcg ggtatcacag acttacaaaa tcttgtatgt aattagagtt 192780 atgttaatgg cacatttata agcaaagtaa tgtcatggaa tggaagaccc ataagttgac 192840 atgagaaaca gaaagtgtat taaagttaat ctgcattcat gggggcagat tgttagccaa 192900 atgaataaag aattagattc atcttcatgg tatgtagcat gaagaattta aaatgaatca 192960 gaggtttaaa ttaactgcag aaattataga gtttcagaaa acgaatttct ctccaatttt 193020 gaggaaatta ctgatgatac acattgtaga agcaacaaga aacacaaaga ttgatagtaa 193080 aaatgaaatt acagagttga aaaagttgtg acatcacata agaagagtga aacccttggt 193140 gtgtaagata taatcgggga aaaataccag ttcaaaggaa aagtgacttg agcacatagt 193200 tcactgaaaa aaatacacaa agtgctgtta atcatataaa aggattcttg ggtttgctca 193260 taataaggat aatgacaatt gaaaatacaa ctaagatata attagtttct ctactattag 193320 actagcaaaa gtccagaagt ttgacaacat tttttttttt ttggcaacat gttcggaatt 193380 atggaaaatc atacgttgct tctgggcatg taaaatgtaa accatatggg taggaattta 193440 atattttgta aatttatatc tgtggcaaat acatagttca tctcctagta atatgtagca 193500 gtaagaagga ttgatggatg tttgtatacc actatgtgat aatgtcttgg atataatgta 193560 gaaatagggg agaagtcggc tacaggaagt aaaaatggca atatggtgct cagggtgcat 193620 tcatcactat aacagataac cattttgtta atggtgccct gcgcggtaac tgaaattgta 193680 ctgggctttc aacagaattt tgtcaaaatg ggacgctgca tgagctaata agttgtgaaa 193740 taaatagggt tttattgtgg agtaataagt aacacaaaga agggggtttg cagtatctta 193800 ggaagaagaa cagacgttct tggtaaagtt cctttaatat gaaaatagca tttttaaata 193860 cttggagtag tgagtgaaga agctttctct atgagagcac ggttagttcc caaataaatc 193920 ccagcctcct ctcttctgtt aatttcttcg gaaggatttg aggtagcttt tgaagtattt 193980 ggtcaaagtt gcaaactcct cgggaggagg ccaggcatgg tacctcacgc ctgtaatccc 194040 agcattttgg gaggctgagg cgggaggatc acctgaggtc aggaggtcaa gaccagcctg 194100 gtcaacatgg cgaaaccctg tctctattaa aaatataaaa atgagctgag tatggtgatg 194160 cacgcctgta atcctagcta cttgggaggc ttgaggcagg agaatcactt gaacccagaa 194220 ggcagaggtt gccgtgagat gagattgtgc cactgcactc cagcctgtgt gacaaaacaa 194280 gactcctcct ggaaaaaaaa aaaaaaaaaa aaggaaacct gagattctgc ttaacaattg 194340 taaagtcaga aggtatgaag agtatttgaa gttagacctg tggacaggct gattggatct 194400 tcagcagtat gagaaagttt agttaagcca aggtactatg taaaactcca agctgtacag 194460 agctctgcct ggccagctgg tcagcacttg ggtaatgagg aattgataaa tggcaaattg 194520 cttcattgaa tgattggatt aatagtagca tgaatggata aattaacggg aatgggtata 194580 taaatgggta tgagatcagg aatattaatg gagtcacaag tagatgatgc gtaaatggga 194640 ctatatgtgt ggattgatgg atggatggac cctgaaatgc atttttgatg gaattaggga 194700 acaagaataa atataatagg aagtgtggta tgcatgtaag catgtttgtg tgtgtatgtg 194760 tatataggtt gatgcaagag tggaagggta gtaaggacaa aaactttgga cagctatatt 194820 gacaatgcaa aataaaaaca tgaatgtatg aatgtatgaa tttgacggat atgtgcttga 194880 aagaatgaag tcagtttagg aaaggataat taacaaatct cagtaatgat tgtaatcatg 194940 tgattctcac agtaactgtt caacagtgac tgttaaggat gctgcgtgct catggcagta 195000 actcatgggc agatgtcaca aagacagtaa tacctcttat tgcttttatg acagcataag 195060 gttttatttt tcactgtggc tttgttagag ttatggaaag tcatccattg cctcttaaat 195120 acgtaatggt aaattgggta aaggaattgg gtaaatcaca tggttttcca aaacttcagg 195180 agatttagaa gctgtatttt atgttttctc aaggaaagga tgaaaaggac acgttaaaca 195240 ctgatagtgt ctactgtagg atacctttct ggtctcacaa actaggtata ctttctactt 195300 aaatggaaac tatccccttc acagtgggaa ccaataaaaa cctcacccag gtaaaaatcc 195360 agcgtctcag tgatgctatc tccctatcat gaggtaattc acagtaatct gtaccttaag 195420 tctcagtgta cctactgttg gcccagagat aggtgaaact taaagataat tgtaccttgg 195480 ctgcatgtag tggctcatgc ctataatccc agcactttgg gaagctgagg cgggcagatc 195540 acaccgtcag gagttaaaga ccagcctggc taacatggtg aaaccctgtc tctactaaaa 195600 atacaccaca ccctggtgtg gtggtgtgtg cctgtaatac cagctactca gaacgctgag 195660 gcaggagaat cgcttgaacc cgggaggcag aggttgcagt gagctgagat cgtgccattg 195720 cactccagtc tgggcaatag ggtgagactc catctcaaaa aaataataat tgaaccttat 195780 ttccttttgt acaatgtaca atgagcagag tcagggcaac tataatacaa ctccaaactc 195840 taaggtgtca aatgtgatag aaatcacttt tccattgaaa ttttgaaatc cctctggaaa 195900 tacactgtga aggctcccta tactgtgcta gagagtgttt tactagggcc tggaagatgc 195960 tcactttttc cttgttttcc ttggctgtag cttttacctc tggcacactt tcccaatccc 196020 cttatcctac ttaattattt ttaaaatagg cattgtggag gatgtttgtt catattttaa 196080 gtcttaatca tgggcttcta gtttctttgg aagtaaaagt gacccattaa aaatgtaaaa 196140 tgtgttatgt gcatcatggg cacaggagtt tcgtggccta tatgtgattc taacttatat 196200 cttaccatgg tgatcgtaga accatgtgtt gatatgtaat tttcaaaaga ggtgaatgcc 196260 cttggcacag taatctgtca tatttagcaa agcttccctg agagccatca taacagaccc 196320 acaggaatat tttcattagt aagaagtaga tgtgttcagc cagtaaaatt ttgaagtggc 196380 catgacttca atctgagtac agagggaaag ttacacacaa taattcagtg attggtggat 196440 aggtgcgttc aaggaggcag ggttggattg gtgttttcaa gcttggtagt agtagtagac 196500 aggcagacat gtgagttgat ggaaggatgc aagaatggtt actgaaattt tctttgtatt 196560 atatggttaa tgtggattta ataactagtc attgaaatta tgtgggattg gatatttaaa 196620 gcccagaaag atgaatataa taatcgtcta atataatttg aaatataata acggatgcat 196680 gcaaaattgg gtgtattgaa taatgtaaga aatagatgga aagtagaata tgagcaaatg 196740 gctggatgca agaatggaga atgcaggttt taaaaacctg ttgggtgtat gtatggttat 196800 atgcacagtg gaatcattta gtgaaggtgc agatggttat atgcctaggt gttatcattg 196860 gatggatcaa aaatggaatg ctgtatggat agatctttag attgatgagt acaaatatgg 196920 ctatctaaaa ccttggataa atgtagggat cagggttcag gtacattggt tgcataagtg 196980 atagctgcct gtttggtggc tttagagtgg cttaatagac tgatagatgg gttgattcac 197040 aaggtgatgg tacaggaatt tgatgactat gagaatgggc tgatgcaata ataaagtcat 197100 atatgtaaag ttgactggaa agatggacat ttgaaagcca atggtatatt ttcacgggca 197160 gattcattat gaaattataa aagttttgtt tttgcattct caacatgatg tgttagcaaa 197220 taagcaaaaa ctaactgcag tgggttcaca agttagttta attaaaatga tctttcaata 197280 ttttaataat ttggggactt taggaggttg aggaatgaga gaacttcacc ttctgtatat 197340 taactggtcg tatgtcacaa ttttcccata tttttcacag ttatagctga ggtggtacca 197400 gtttaagaag tgagaacttc ttcactgact gaaatttgca tatcaatcca aatcattgtg 197460 cttatttact atttttgtag acgtcattct tcaaaagtgc tggtaagaat cagtaaccct 197520 ggtgtactgt ttatttttga ccagtttgat attgaatcta atttgtaata ttttaaaatc 197580 caaaactata catgaattct ataaaacaca aagttgtgaa tttgtggagt gattatcagt 197640 taggtgaaat aaaagagata aaagggctcc ctaaattttg acacagtttt gatatgtagt 197700 ttatgcaggt tttgatttac cagtcttatc tactctcacc gtagtatgta atgtcatctg 197760 gactgagact ataacttttt atctgtatac tcagtaaatt ttatattatt tcagtaaatt 197820 ttattgaata aatgctctgg aataaattca tcagctagag ggagataaga aggaagtctg 197880 gcagcctgtg gaaaataaag aaaatggata ggctattaaa agatgtcaga gaccaaagtc 197940 attaggaatt agaatttact ataaatagta tgggttataa tgagagtagc aggtttaatt 198000 ttagttccaa gtgcatgatt taggatatca tcagtaagta ggtaaggtca gcagatagga 198060 gttgaggaat atttcaacat tgaagtggta aaagtagggt cttaacaccc tttctttcga 198120 tgagtgaatg aaaaatcttc aactattttc caacattcct gtttttcttt tttttcacaa 198180 gcatcttcaa tagtcaagga ggacaaagac atctttcctg caggtaaaat cattaaagac 198240 tatattgtga ttttgaagct gttctatttg ctacgttgag gatatattag attcttattt 198300 gagttctttg aaattaaatt tcttttctca tacatcctac tttgtggtta tgtgattatt 198360 ttgagtcgat attttaatca aggactttat agttaactct tgttaataac caacatttaa 198420 tgaaatcagg cattttcttg actttagtac cacgagaagt tgcacaagaa gcatacaggg 198480 tagcaaggag aattgatggg tggatactgg gttttagttt gtggaaagat cttaatggaa 198540 tacacagagt atcttattag tatttcctta tattgtgtct tttaaaaaaa ttcttaaccc 198600 ctgaattggt gtataaatta gaatgaagaa actacacagg aaatgctggt tcaaagaata 198660 aataggtggt tggttggcgt gaaaataatt tggaatagga gataggtatt caaatcacaa 198720 aaaaatgtgt agagaaacga aggaaaatgg cagctttatc atttgcatac agtacgtata 198780 cctggttttt gtaggttttg ggttattcca catcagattg taggagttcg gttttatgga 198840 gtattacttg acttgaagat gatatatttc tgtcaccagg catggctgtg tcataacctg 198900 ttgtttattt ccatttgcaa tctcttcttc tgtactctct caggtggtga ccatgtggat 198960 aataggatca tagacaaatg gtggttccat ctacagcatc accgaaatgc tgttgttact 199020 gcttctttct gggatcttct tgcatctttg cttctaaagg ggcacacctt ttatagaagt 199080 acgtccagga atagaagtga cctgcttttt cgcaagtaat tgcctggaat gtttttatgt 199140 acttctctgc actctcaata catttcatgc ttccctctat ttttgtatat taactcattg 199200 tatttcttaa atttatattt tactttatga atggaagtga gatttgtgta tggtaaatat 199260 aattaattca accccatgga tacgttagtc actgtccaga tgatggcaag tctttctcag 199320 aagcagaggg ccttggtgtg ccagtgattt tttttcccca tgtgtaagat actttttttc 199380 ctcatttgaa tcaggagccc acagttttta gacaagtccc aaatgaaatc ttaagcattt 199440 gtgttatctg gactagacct tctgtagtat cctttttgtt agacctagta tatctcattg 199500 cagatcagga tctgagattg actatagttc acctctttcc aagtacacaa acttggatga 199560 catgacaact gagtgtgtaa gggagagcga gacccttgca ctgccatttg agcccttgtg 199620 atctcatctt gtagaacatg ttgtacaatc attttattgg tatcattagt gttatttggg 199680 gctggaataa aaatctcagt gcaccaaaga gatttcccct ttatccacgt taccctggtt 199740 ttcctttgtt ttctgtttaa cctaaacggg cttaatataa aatagtgctt atttggtgtt 199800 ttaattgtct gcttctataa cataagctgc actgtccatt ggggaactgc tcaccatatt 199860 gcccaacctg tcttgatagg tttatacatg ggaggcattc agtaatatta attacctctc 199920 tagaccagtg ttagcaataa caaacacttg ctagaatttt aagactatat aatcaatcac 199980 tttgatgtca gttaatccta ccaacacaag attaaaggtt taaaaatctc atacgtgtac 200040 agccattagt gtctcctttc atactatatt attttgttca ttggcagcta gatttttagg 200100 tagaacttgt gttccttttt gcaatgctca tttattttac ctggacagaa ggtgctcttc 200160 tgtctcttct ccaaagttaa tttatctcat actatttctt gtgttaatat tttccaagtt 200220 cagtatgctg ttctggttat aagaagatca gtgtcctaat cacacacttt tacattatat 200280 gaaacatcat acagagtttt gtagtctgta taacaataca cagaggtagc aaaatttgta 200340 aaagagcaga ctatatagtc catactgtag taactactca acattgccat tatacgtgaa 200400 atcggctata accaattcat aaacaaatga atttggccgt gttctagtaa aacttattta 200460 caaaaacatg tgttaggcca gatttggacc acaggctgta gatttctgac ctctggctta 200520 cagcagaagt ttattatgat cctggggaag gtggatatac atggaaggca gaagcgagaa 200580 gatgtattcc atcccatgtc atttttctga accctcaacg taggaagtta aactaaaaca 200640 tggggcagaa tctgctttaa gcctttgaat tcttggctct taaagccagg ttgagggtta 200700 tgtgttttta ttcttttata tctccttttc acttaggctt ggcaactagt tcattgaaac 200760 agagccaaca agaatgagtg agtcactcag tgatatgaag caagctgtgg tcatttatct 200820 actaccttcc atacctactt cctaggtttg ataagtagtg tttgtagtgt agttgtcagt 200880 aacttttctc agcttacata agtttatgtg gaattcattt acaaatgtgt gattattacg 200940 atagatgtta ttttataaat ttcaaggttc tttaatacag catggacatg tttctaaatc 201000 aataaatata gcttacccac agacttttta tgggatgtaa agtatgtatt acaacaggta 201060 aatccatttc tctgttttgg gaaagcaggt taatgttttg tttgttttgt tgctgcatat 201120 aatgttgcac tatatatata ttctaatgca gttggtctcc taattctaca ggataaatgt 201180 ctagctgtgg cattgttgga tcatcagttt cgtttcagtt agatgctgtg aaattgctct 201240 tgaaaatggt gtcctctgcc accacagaac ggtgttgtaa tggaagtgcc aattttcata 201300 aaaacttgtg tgcaacaggt attaagaatt tttgaggtcg ggcgcagtag ctcacgcctg 201360 taatcccagc actttgggag gcctaggcag gtggatcacc tgaggtcagg agttccagac 201420 cagcctgacc aacatggtga aatcccatct ccactaaata caaaaaatta gctgggcgtg 201480 gtggcatata cctgtaatcc cagctacttg ggaggctaag acaggagaat tgcttgaacc 201540 caggaggcgg aggttgcagt gagccgagat tgcaccacta cactccagcc tgggtgatga 201600 gcgaaactcc atctcaaaaa aaaaaaaaag ctttaaattt ttagccaatc taataggtga 201660 aaatggcatt tttaacataa gtctgactta aacaattaat ggccgtggct aaaagaagaa 201720 tcaaataatg atgtgtgatt tataagataa ggaggcagta ccccattttt cctcactcta 201780 cccaaaaatc ctgtttatct gagcaagaaa tcattaatat tttctaaatc cgcttggaag 201840 ttcataaacg ccctaagtat accttatacc agcgttttta tgactttgta tttttgaaat 201900 aattttagat tcagaatcgc aagaatcatg cagagcgacc tgatttacgc ttcacctaga 201960 ttgacttttt attctgcatc gttgtgttct tcccccactt cctcttcttg ctctcgcctc 202020 cctttatatg tttatacata gcattatcat tttatgtact atttgaatga tttgccgaca 202080 ttatcttcct gtaacccaaa acacttcaac atctactttc taagagcctg agcatcttat 202140 attgacttcg gtaaaaattt caaaataatg aaatgtgtca atagtataaa agtataacag 202200 tatgcagtcc atattcacat tttacccatt tttccagagg tgttctttat agcagtttct 202260 tcccttctac aacatccaga aaaggatctt ctattgcatt caattatcat gtctctttag 202320 ttttgtttaa tctgaaacag tttcctggac tttgatcaca tcagtgttct taaaaagtaa 202380 tagctaacag atttaaggag atacctcaga ttttgaattt tgtgtttcct catgaaaagg 202440 tttaagatac tcattttgag cagaaataat tcagtattct cagtcttcct tagtgaatca 202500 tctcaggtga caaataatgt cactttgtct cactttgaat tactttgatc tcttggttcg 202560 attggtgtcc actggacttt tccactatag ttaacattcc ttcataatta atttggaact 202620 atacaggtat tctatttttc atcaaacttc cacatagtag gtttaatatg cacaggtgac 202680 ttttacctga atcagtgttg attagaaaaa aatctgttat tgcttagatg cattatttag 202740 tatcttgtac tgtaaggaag agtttgtata tcatggcctg tcagaacagt cccgcaatgt 202800 gttttatgaa ctgaaaattc tgaaagaata aggtagtgat ttatatgaga atacagggaa 202860 agggttaccc aaagagtcta atgaatttat gtctaaacca tagagtggaa tgtgagagac 202920 acacagaact ccagagttgt gatgcaaata cactgcacag tggaaggaga agaggaagtt 202980 tttggtaata gtgtttcatc taatgtagct ctgtaatgta tgtgtgcctt cattattgga 203040 agagtgttca acagttcaca gttgaataga ctgaagcatg atgctggaat ctgggttcag 203100 attctagatc cgtatcctac atatcaccaa tgcttgtttc tcaatttttg tttgtcatta 203160 ctttaagtct ctttaatgca ttagagtatc caaggttgac agtgaaggga ctgcatttgg 203220 gagctatctg aagacaaaaa cagctttttg aagtttcttt catacgtcac cttacatggc 203280 ctctcgcatt ctctgtggag aagtttgtgt agattattca gactaccgtg cagtgactgt 203340 gttgtttaaa acctatacat atccaaactc tgttttgtgt tctctataac tagggcatta 203400 gtctcccaat agtaatcctg catcttatgc tatttaaaga aggttcccag aatacagaca 203460 ttcttacttt tgaacaatga cttgggtaga ttgaggaagt ggttttaata atcactttga 203520 tatatttcaa aatctggttc attattggtg aggtgcaggc cacctggtat taatgaaaat 203580 gtgtaattag gaaccagtgc agtggaatca gaggcttgaa catgacctaa ggcttggtca 203640 aaagtggtga tctgaatgtt ccctgctctc tgtatgtaac tttgtactta gtcttcagtg 203700 gcagggttgc agcagaggcc cagtaaatat tgttcattca acgtatgaag gagaaaatgg 203760 aagtaaggcc aaaaattact gattgtaaac aaatgaagca ccaagtgaat aaatgtacaa 203820 atagacaagt agccagtagg aaaaaaaaca ataattgtta cctaaagaat gaaaaccaag 203880 tggaaaaggc cgccagggac attttaatat gcatattgtt gctttcacat ataatacagt 203940 aagggagtat cagaaaacct gaatctgcct gactaaaaca taccctgttc cacaaagcta 204000 tatatatgag agtattgaag gtggtttaat accaaattca aaaattcagc ctcagtgtag 204060 caaactttta aattttccat gatataaagt aagttttaac caacaatgga agtcacagca 204120 ctaaagtaca ttactattat atgattctct gatggtaata gaaactgtgc tgcaggacac 204180 gttttgattc aggaagaaat gtggagtaac tccacagagg aattcatcct ttctaagttt 204240 aaatctgaac ggaacccata tgcccatacc ctgaagatgc atgtaaggga acaacatggc 204300 ttggtctgtt gaaaaaagaa aagaaccttc aattaagcat tctgtgaact tgataagagg 204360 atgcagagga acgtaaatgc actctgcata tctgtgattg accttggaac acagtgattg 204420 ccctctaaag aatagccgag taagtactgt tatcattcca ccgatcaaat tagagcctct 204480 tccttccagt gggagcagag tgacatagac caaggaaagc cgaggagaag attgtagcct 204540 tttatttctc cttatatttg ttgaggttca ctgctgactg ataaacgatt tgcacaaaaa 204600 aattcaggcc tctgactctt ctggtatttg atttatctag taaagttaat tccaagacaa 204660 aagtacagtt ggttaaaaat accagtctca tgtttatttg atggtttgaa atattctgtt 204720 acattgttgt atctcgtttg tcaccttgga atatatgaca atcatgttat cttgattttt 204780 tccacaagat aatttgattc taaaatcgat tcattgttta tcttcaggaa ttagagattt 204840 taaaaatgtc atctcatgtc tcattcagtc atttccaaga tttagcgagt gttctcccta 204900 atgccttgga taagaatgcc ttgttcaatg gctgtatttt actcataatt agcattccaa 204960 ctgctttggg tttttttaga tttacaattt ttatttctgc agtacttaac tttctatatt 205020 ttatgtatat taaaacaagt taggtaggat gaagatcact ggatgatata aatactaata 205080 gcaaaagtag aaataagttg tattatataa gttgtacata ggtgttacat taggttgtct 205140 tacatgaaag tattacaaag tatgggattt ggggtgtatt ttgaaatcct tgccagttct 205200 acttgataaa gtattgaatg gtatcatgtg agaggagaag aggacggaaa caggacttat 205260 gatttagacc tcaacaactg ctagggaggg ttggttttct ctgagtgcat gattttttat 205320 aaaaatgcta ttttgccagt tttagatcca tattaaaccc acagattaag gttttggttt 205380 ttaaagtgta aataggaagc ttgagctggg ggggaatttg gaggtagaga taatacttaa 205440 tcgctgtggg aaaggatgag atctagagat agagtgtatg tgggagtagg aacatatgtg 205500 tctgagacca tgctttggat gctctagcat ttagatattg agaaaatgag gaagacccat 205560 taaaggagat tgtggctaga gttactggtg aaaaccaaag ggttgtagtg ttcctgaaga 205620 tacatgaaga gtgagattaa aaattaatgg ggcagcagtg gcttttgcat ggcattgaaa 205680 agacacagtt caatttgaaa attgagtatc attaatcgta gtgctcttat tattgaaaag 205740 gccaaatcaa acaatacctt tgagttgatg gtctgtacta taattaggtt accattgtta 205800 gcccagcata gacacatgct gatacctgtg agttgctttc atcaattagt atgtgaagat 205860 gcatcccagt tgtacaattt tagatcctct tcatcattcc acattatatg tatacaagat 205920 aaaacttgat gttttcatta catcctttca atcttctaac agcagtcctt acgtagcttt 205980 atcattggag tttccacttg cagtgtctct atctgtacct gcattcattg gccacggtag 206040 agttttcatt acggcaggat tgcatttcat tgttttggct tgtgtcagac atttagcaaa 206100 gattgttgag gaaaggaatg gatggaaggg gccagctgaa agaaaaagta acaacctaat 206160 gatggataag tgaaaaagga atgaagaaag gatggtgcta ggaatcgagg gagtaaagca 206220 agatagaatg tacaaaaggt cgaattttta aagaaagttg tagggcaagg gcaaggtgtg 206280 ttgaacctac atttaaaata caataacatc actaaagtcg aggccgggtg tggtggctca 206340 cccctgtaat cccagcactt tgggaggcca aggcaggcag attacctgag gtcagaagtt 206400 tgagaccatc ctggccaaca tggtaaaacc ccatctctac taaaaataca aaaattagct 206460 gggcgtggtg gcgggcgcct gtaatcccag ttacttggga ggctgaggca ggagaatcac 206520 ttgaacctgg gaggcggagg ctgcagtgag ccaagatcat gtcactgtac tccagcctgg 206580 gcgacaagaa tgaaactctg tctcaaaaaa aaaaaaaacc catcactaaa atcagggaga 206640 aaaaaaccat cactaaagtc agggataaag taccattgtg gaaggtgttc ttttccagct 206700 taacctgaag aattgtacag tcattgtaca ttgtcattcc ctaactaatg ggttagatat 206760 gagtctgtag aaaattgttt gtccaacata ctttatgcct cttaacattt cacttaccaa 206820 atttcatttc attccttcat tttgtgtcta acagactaga aataatgagc tcctattgac 206880 agggatattt tcctcttcat actttccttt accttacaga gccttttatg tagcagatat 206940 ttaatttcat aatgggtcta aactacttgt ttagaccatg gatgagtgaa attttgatga 207000 atgagcccca atcacctgaa gggtgagtaa aagaagaatt tctagagacc caatatgaag 207060 tagctgcttc acactttttt gagaatgtta tggcatgact gaggaaatca tagatgctgt 207120 agaccatgtt gagttggatt gtgtaaatat agattctggt attagggaac tcagcatctg 207180 ctggattaga cttcttatgg tgaaagtctt tttttaggga ttaggcataa atccccactg 207240 atatttgtgc agtaatagag tatagctcct gttttctttc ctgcttgtat agcctgtgcc 207300 attagtgtcc tctttctcac tgttttctca aaggaaaaca gtcaaagagg aagccatatg 207360 catggtagac tttgtaatcc gggaaaagtc aacatatttc atagtagtgc actttttatg 207420 tgttgtcagt ccttagaaag gattcatttt ctccatatta tatactactc tattttaaaa 207480 atttcttggg ggagaatggc tgtagacagg ccaatgatag aatcatagaa tatagtcact 207540 gtctaattac tttcaatcaa gagagggaac aataaagtac aatgtatgtc gctgacttca 207600 gtgtgaccac tcagtatttc tgtaacacag tatttatatt gctgtacggt agagttatac 207660 ttatttctgt gatccagttc atttgtttaa tattgggatt caaggagtgt tgaagaaatg 207720 tctactgatt aataacagat gggaagagtg tatgtgtttt aaataagaga ccaagagaga 207780 caataaggaa aataagaagg aagtgtttgt gaacctttca cattactctt acattcggga 207840 agtccacaag acaccgtagt ggagattctg aggaggtgaa aacctgtaga aaaatgcttt 207900 attagtaagg agctgactaa gttgtcagaa agtgttgatt tttagaagga tattgagaca 207960 ttgggtatat agggtatatg actccttgtc ttcctttcat tctggcttct taccagctgt 208020 tgtgaataag tttaagattt cttctgacgt tataaacttc agaaaaggta tggctgtttg 208080 ttcagtttga agtagtatca tatccgccaa agccttgttc aattgtcttg ttgattcatg 208140 gttctcttca gtgataatat tatatgggat tcctacccac agccacccaa tatctcagtg 208200 gagaaatgca ggtttggaga gaacatctga atagaatcac gctaagatgg tacatttgca 208260 ctgagaccat tgttatgtgg caggcagaca tgaagtatcc taggattgat cagtatgcct 208320 taatgtaaat agctgcatat agacctgatt tcttaggctc cccacttcaa gctcttgaat 208380 attgtgttga tatccttatc aatacacttt gtcttgtgtt ctgtgttgtt tttccaaaat 208440 ataacgagct cctacttgac agggattttt tctttctatt gtcttacgat aaaatgtcaa 208500 gataaaaatg tatgagtttc attaaagttt attgaataaa atttgtgatg gaatgagtga 208560 cagcgaggtc atgaatgaga gagaatatgg aaataatgga gaatgtgata ttctgatagt 208620 catgcaatat tctttttgat ataatatgta acatatatta gtatgttata ttctatgtat 208680 tatttgtcat atattattac tatatcctgt tgctatattt ggataatttg ggaatctgcc 208740 atgtttgatg atgttgaaaa gagaacataa aatgtagtga tttcttaata aggtgtagag 208800 gtgtaggtat taactcttta agaatatagt gatttatttt aaaataatga taggaaagga 208860 ccataaaaat gtctgaattt gggaaattag aaaatgtttt ctctctgggg ctttcatatg 208920 tctgttctat gtgaatgtcg ctttgccatg gctccctctt tgctaactct tcttaacccc 208980 tgcagagaag gaagtgtagt gatggtattt tgagtccatc ttcaggttta ttgggaatgc 209040 aagggaaatg agttgttacc aatgggagta aagggctagt tgctatgcca gtagctgcta 209100 cttttgacac tgcttgagca atctgaatgg ctaggtttga atctggcttc tcagtcagaa 209160 ttttaccttc actctaatgc tgcttttttt caaatcacct atatttacat aaatatgaac 209220 caacttcagt gatcttaatt ctttcccgaa gatccaagtt tctttccatc tgcctgaaga 209280 actttcttta gcacttctgg tatagcagac ctactgatga taatttttct tttagtatat 209340 ggtgattagt ttacttttta ttcaactgtg tctttttttg aagtcttctt cattgaaata 209400 tattgttact aaatatagaa ttaatggctt tctttaagca cttcaaagat aatccactgt 209460 tttctggact ccgttgatac ttaagtcttt atttttgtgt aattcttttt ctttaaatgt 209520 gccatttttc atttttctct gactcctacc tactaagata tttttaccta agtattgagt 209580 cagttttggt tatgatgtga ctcagtgtgt ttttatttat attgtttggt tgtttgaact 209640 tcttgaatct gtaaatgttg tgctttatgt taaatttggg gggatttcag ccatttaaaa 209700 tataactttt cagtctcttc cccctgggac tccaattttt acatatgtat tagacctatt 209760 aatatttttc tatggatacc tgacattctt tttaaatctt atttttggtg tttttcactt 209820 tgaacaacct aataatttgt ttccatccat gttcactcac tgtttattct attttttccc 209880 aatctgctct taagcctatc ctgtgaattt tctttttaat ttattttatt ttttagttcc 209940 agatattttc tgctttttgt ttgtttttga gacagaatct ttctctgtca cacagggtgg 210000 agtgcagtgt catggttcac cgcagccttg acctcctggt ctcaagtgat cctctcacct 210060 taacctaccc actcctaagt agctagaact acaggtgcat gccaccacgc tcagctaatt 210120 ttttattttt gtagagatgg ggtcgttgtg ttgcccaagc tggtcttgaa ctcccagact 210180 caagcagtct tcctgcctcg gcctcatgcc cgcgccaacc agttctttat ttttaatatt 210240 atgttgtatt tgatgtgcta tcctattcat ttagtataag cacatttttc tttatgtctt 210300 cagcataatt atatgctttt tcagaatttt aacatcagga ctgcttccag ggtagcttta 210360 ttgccctttg tcttaagtat ggattatagt tttcattctt tgtatgtcaa gtaattttgg 210420 attgtaactt gaactttgaa tatactgtag aaactctgaa ttctatttta ttcttctaaa 210480 acaatatttc tcagcttcag cactactgac attttgaact gggtcatttt gtttgtgttg 210540 ttgtgtgtat tttgggaggg tactgttcta tatgcattgt ggggtactga gtattatcct 210600 ttgtctccac tcactactta ccagtagcat aactctctct cctccccaca tcccctgcca 210660 aaaaatgcct tcagtccttt ctaagcgctc ttttttatgg tgttggggcc aaaatcatgc 210720 atctttactc actctttctc attgagagct atggctataa agggtagtga tacttttact 210780 tatttatttt taaggcaagc agttaactta gctggattca aactccaggc tgcctcgtgt 210840 gctgtgggaa gcagcctacg ctctattcag ttcttttctt ttcatattgg ttgggttact 210900 ttgagtctgg cctacatgat gggcagttta gaggtcaacc aaaggatttc agcagaactt 210960 atacacagaa tttcattcag gcttcccgtg tctgattggc tacagtgtgg gaatttcctc 211020 ccacttttca gccactactg aggatgcctt tcggcaaaat tccttgaaat tggaaactta 211080 cagggaaatt cctttcctcc aagagtgcgc tctcctccag tgttggcttg cttttggttg 211140 ttctccgtgg ttttagatag ctgtctttat attaattctg gagtttacag ttgatatctg 211200 ttgggggctt agtttgataa catgtattct tctattacta gtagccagac ctgtatgtct 211260 tacttgacct gatggagaaa agtttcaact tatgagacaa tactgtgcta gctagtttta 211320 ctgatttgta ctctaaagta cccaagccta aaatagtaga gctgtctatc ccacatgaaa 211380 cttctctgat tttcactgtt ttttataaaa agtatacatg ttcacatttc tgtaggtttt 211440 tttaagcatc acaattttta taaactttct atatttccaa ggtctacctg ctttgtattt 211500 tgcctagtga gagttttgta ttcatgtagg aataatctct tggtgtgagt atctattttc 211560 cactcatcca aaacagatag agcattgatt tcactaagcg ttatgttcta gtttgctttg 211620 gtattattat tagaaatacc tggtgattaa tttgagctaa gtattcttct ctaccctcat 211680 tcccagcatt atcacccgct tttaccactt ccaaggggtg gaagcattct ccacaatgca 211740 ttttttcatg ccagagaaaa atctagaaaa aaatgaataa aacgaagaaa ttctttcccc 211800 ttggtatctg tagctaactt gcctaagtgt tctttcccac agtttaagtc ttcagtccat 211860 agttcataag caaaggggtg tagcgagctc tgatcttgcc agaagagaga ataagtgagc 211920 taccccacgg tggacattct ggccatctga aatgagtcga tgcatgtggc ttttgtctaa 211980 aggctacaaa taaaatgtaa ccactttctt ctttgagtag ttgatatagc aaatagttga 212040 aacagaagtt ttgattggca aatcaggatg tggtagatac tttaacaaag agtagaacta 212100 ttaccagttt tatgtgttgc tgtttgtatc tctttcacag ttttgataat atcacatcct 212160 ggaaagtgaa acagaaaatt attattccat tttaaatgac taaatttgct ttcatggtat 212220 ttacagtgaa agagtaaatt agaaagtgaa tggatgactg ttcatgagaa aaagcagggt 212280 aaaaagattt tatttaatta attgaaaata ttagggtcaa aacataggct tatgttatgt 212340 tttgtgaatt gtgctgtgtt gtagacattt gatgagtcct aacatagaat tgatctagct 212400 cttgaaatac catttttgat tgagtataaa tgggatatag gcaccttaca acttcagaat 212460 tcgaggaaga tgatgtgaat cttccaattt tatctatttg attcaaatgg tatgtttttt 212520 cacatttctc ataatttcca cgtcaactcc catgatgatc atgcaggaaa gcagcatgat 212580 tgcacttctt gtagtgcata ccatcactaa aacatagtta ctgtctttct gtggtcttaa 212640 gaaaaattca gaaacagcat accaatgtac atataagata aataagctta tgtggtacag 212700 taagtgttct gttctgagaa ataccttgat tcgtatccta atgtctgatg ttattggtag 212760 ttctcaaact tccccaattc tgctttcatc taaattcatc ttatctatct attgttaaat 212820 aatctatcag tccattttta tctatcatct atatatctgt ctttatcaat cattcgtctg 212880 taatctatct gtgccgtttg gcataagaga cagaagggca tagcagtgga aactcaaagg 212940 agttacctcc atgtgaatgg acagtggtga tggtgatctg tgaggtggtg atgtatagaa 213000 agaaaaacta gaagagagca tgccctaact cagggacctt gtccagcagg cactctggcc 213060 ttgttatact gtgcttgaat atgaaaaaaa aaaaaatcaa aatagtgctg acattctttg 213120 tcttctgggt ctgagaaaac ttagagtaga tatgatgact ctgccatttc agtcttttgt 213180 atttccacat ttagagctca gttttaatta tgtagaatta tttctccagc ctgtgttaaa 213240 ctagaccatg gattggcaaa ctttttttgt aaattgccaa atacacattt tcagttctga 213300 aagccttgtg gtctttgttg cagctaatct actctgctgt tgtgttatga aagcagccat 213360 aggtaattta taattgaatg agtgcgctgt gcctttcttc caataaaact ttacaaaagc 213420 atcctgtggg ctggagttta ccctttggga aaccagagca ttggctaaac tggaacctga 213480 aaaaataatc acatcaactc agccacatgg taataatatt tagagtatta tttcaacatt 213540 ttcattttca taaaaatttt tttagctctt ttgccaaatt ccatctgtga gtgatacaaa 213600 tgactaccac gtgccattaa catcacctaa acagtgcaaa acaagcatag tagaagtaat 213660 tggaatgata taaacccctt gctgtaatag ttatagttga taaattatgt ttcaaaattg 213720 aacctatttc ttccaaattt catctataaa gttccaagga gttccaaaat cttgcctgcc 213780 ttcttttccc agttagcagt attgtctctg agcagccatg gtggtatcca tcctccttgg 213840 acaatgaatt tagcctattt tgacttcatt tgagcagttg taattgtttc accacatcag 213900 agtaagatta ctacatgcca gagctattct ttaactcagc ttgtaaaaac atgatagcat 213960 caacaatata catagcaaat gaatgccatc tttaatccaa ttaaatggtt tttacaaatt 214020 tgctcttgtt tgttgatgct atctgcattg cagtaattaa aggtgaggta aaaagaatga 214080 ataaactgcc aagttaaaat taaatttggg caatttctct tttgcagtaa tgtatgtata 214140 tttactcaaa acatatgcca aatttagtgt tgaaaggctc attcaaatca attgggaaag 214200 cacgtaaatg aacaattcat aaaagaaaag cattgcaaat ggccaagagc atagaaaatg 214260 tgctcaatct taccagtcat tataaggaaa taatgaaatt tgtgtatata tgaaatactt 214320 aaaatatata taaaataaaa caattatttg ccttttttca cctatcagat taacagatta 214380 tatgtgttaa caaggtgggg agaatttaca actcctgata tgttaaaatc tttcaggaag 214440 gtagtagaaa atatatgtaa gatggaaatt agcacttttg accaacaatt ttagttttag 214500 atatttacct ataaggatat aataggaggt gttcaaagat gcatgtaact caatgtagta 214560 ttaattataa ttgtaaaata gtaaataaca tttttgtcaa atcataatgt taggaaaatt 214620 agtgatggca catttaacca attgaattat attcagttct gaataccgtg atgcatgttc 214680 aaattaattg atacaaaaat ccaacaactt tagcagtttg tttaccagtt attgagtacc 214740 aactgtgttc aacattgtta tttcactcat atgaaatgat aaatgtatgt gcgtgttatg 214800 atacggtcaa taaaaccact tttataggaa gaatactcac aaaatacagc gagttctggt 214860 cattatttta ttgttgcatt tgtgtgtttg tgtgttttga atacatacat gtatttcaat 214920 taactatagc atttattgaa tttttatcac atgtaccaga tggggagatc aacactttac 214980 atgaattata agttataata taataactta tataatgtta ttatataata acttattatt 215040 ataataacag atggaataac gaatttgtct ttttaaaaga taagtaaatt gaggttgagt 215100 ttgaattttg taattcattc tattatatag aagttaaata aacctatcct aggatgtcac 215160 aacctttgga taataataat taaaaatact tatgatttat taaacccatt gagcaaaatc 215220 atgttttgtg aaagaaccca catttcagaa gtcatattca ttcttctttt gtctttaagg 215280 ccagagacat gataattatt aagtgcagct tctcaggaca gaaagtgtaa gtgttggtat 215340 attgtaggaa caggagaaaa acatgaatag gaacttgtct tttggaaatt cttacagtat 215400 aaacctttaa ggagttactt ctagaaatat ggggtgcctt tgctcaggat gtggaacaac 215460 atgttcccgg gcagaaacca tattatacac aaagctctga gacatcatgg aggcacagat 215520 gaaagtccaa agagaaatgg ccagtagaaa gaggatcact aaatggaaga agctaacttt 215580 ggaatagagc tggtgacagg taatatgatg acttaaatgc tgccaatagc agggaaaagg 215640 tccatggtaa tatctgagtg aagaaacaat tgccaactga tctagatttg aagggcataa 215700 cctcttggaa tatttttcca gtgtaatttg tgatcatatg gtctggattc tacaaaatct 215760 cccccattct acaaaatcta taatcagttc tcttccattt tcttcattca ttctaaccct 215820 tttctaaaga cggcactttg tgtcttgtga atgcaatccc ttagcagttc tcagctagta 215880 gctgaaactt tggttaaaat ggtaagcatg ggggattgtg acataaattt tgctttgcta 215940 tggcagttat tgaaatattt ttataatttt gactatttgt catgtaagga atgcacagtg 216000 ccattctaac tgtgtatatt ctggtatttg gggggttgga aattgactat atgagattct 216060 tgcagctggg tctctgacat gttgagaatg ctgaagaaga aaaagtacag aaggagaaag 216120 cagagatggg gaaagctgca tccctcaaat aggataccac tggatactga gcagtgaaca 216180 acctctggtt ttgtcggaca ccattttgga atatttggac acagtttccg gaaggatgag 216240 agacctaatc aatggtagta agatgtttaa aatattatta atacgaatga atgcttaggc 216300 aaggttgacg gtaaagctct tctgtacaat aggtagcgtt aataaagaaa tgacaagatt 216360 tggaaaatca gtatttggaa ataatcataa ttgtttcagc caggaatcat caaatgatgc 216420 taaaacttgg agaaaatttt aagagaaaca ggacatttgg tgtccttatc agttacaaag 216480 ggaaagtagt agcttcctga tggagaacat ggttgacagc acctgaatta aagaggtgaa 216540 agttaatacc acagtagtgg gaacatcagg cagcgctgat aggatgcact gagaagaaca 216600 cagtctcatt tctgtagtat tactgactaa actgcagaaa cctgagtcta cccatgagga 216660 aacatcagtc tcaaattgac tgatattttg cttttagtat tcaaacatac taatttcact 216720 gaggaaatgg tccagattat ttcagactat atagacatga gaatggaata tcacattggt 216780 tcaggatgtc tataaaagga taaggaaggt tggcaaaatt tgaagacagt ccctcaagta 216840 gattatagtg ttacgtgagt attaattgcc taagttatat aattgcctga ggttatataa 216900 cagaaaattc ttgtttttaa gaaattaaaa caatttaaag gataaaggga taatgtcata 216960 gctgtaattt tccaagcatt tggataaaat aatatacatg tttcaaaaaa aaaatgaaac 217020 agatgttgta agatgttagc aaatagggaa tccaggtgga aataatccag gaattatgga 217080 tagtcttgta tctgttcagc aggtctgaaa gtagttgatg aaaataatgc aaaagaacat 217140 gtcaaaaaga aatggtttgg gcatatggct tcaagcatac ataaatgctc aggaaacatg 217200 aaaatgtgaa ataaatggat gagtactata ataccagcag gccttgtaga tacctgcatt 217260 tgaagcattt atattagaag gaagcctttt tacccagaat ttttttcact tagcctaatg 217320 ttttcaaggt ttggccatgt tgcagcatat atcagatctc catttttttt gatggaggag 217380 tgatattcta ttgtataaat atatcacatt ttgctcatcc actcactagt ttttggctat 217440 tatgactaat cccgccagga atatttatgt ggaggttttt gtgtgtttat gttttcaatt 217500 ctattataca tgagaatata gtaactgtgt ttatttgaca ttttgaggac ctgtctgtaa 217560 gtgatgttta agataatttt tgttacattt gaaggcagat aatagtctat gcaaaatgaa 217620 tattctgttg aatattgatg tgaactattc ttattgtaaa aaaaaagtta cattgaaata 217680 gtaagtatag aagttatatc ttggtggcgg ggcgtggtgg ctcatgcctg taatcccagc 217740 actttgggag gccgaggcag gtggatcaca gggtcaggag atcgagacca tcctggctaa 217800 catgatgaaa ccccatcttt actaaaaata caaaaaatta gctgtgcgtg gtgatgagcg 217860 cctgtagtcc cagctactca ggaggctgag gcaggagaat cacttgaacc caggaggcgg 217920 agcttgcagt gagctgagat tgtgccactg tactccagcc tgggtgacag agcgagactc 217980 tgtttcaccc aaaaaaaaaa aaaaaaaaaa aaaaaagtat tggtttttgt actcaacaag 218040 cagttttatg tttttatttt tcaggaactc tccaatactg aattcaggct gggatattag 218100 agaaaaggaa aatacatgaa actcagtggt gttttatggc actttgagtt ccccaattca 218160 ccttcaaaca tttagccttc caagttctct gccaccgtat cagtgcatcc ctcctgagat 218220 tcttaattct ttgattgtgt aaagatggac tatgcttact ccatcttact tctcttaggt 218280 cttacaatgg aagtgcccta ttacattttg ttcttttcta tgatttccaa ttattttatg 218340 aaatttttca tttatttttt ctgttctttc tatctttaat ttctatgtaa ctttttgaaa 218400 tagatctcaa agattttata tatatatata tatatatata tacacacaca cacagagaga 218460 gagatatata tctactgtac tattgaagta gattcctaaa gtttttatct cttctagaat 218520 attggtttca caacacccct attatgtgta tttaatttta cccaccacat ggcgttttca 218580 aaaagtcttt atttggcgga atacaacttc agaatctgat tcgaagagaa aattgctcac 218640 agccgtgagc cactgtgcct ggccgatttt tactatttaa agaaggaaga attttagcag 218700 cgtggggtgg ctcatgcctg taatcccagc actttgggag gctgaggtgg gcggatcact 218760 tgaggccagt agttcaagaa cagcctggcc aacatgacga aaccccatct ctactaaaaa 218820 tacaaaaatt agccaggcgt ggtggcacgt gcctgtagtc ccagctactc gaaggcttag 218880 gcaggagaat cgcttgaatc agagacaggg aggctgcaat gagccgagat tgcaccactg 218940 cactccagcc tgggcgacag tgcaagactc catctcaaaa ataaagagga attggaggag 219000 gaaataaatg aataaatgac aaaggtgaca aaggaccaaa gatctgtgac ttgtgcaaag 219060 attgctctgt ggtaattatt acagaaacaa tgtttgtatc ttatttttta gggaattttg 219120 tatattgtct aatctgattt actttgtttt taatagtttg ctgcaggtct agaagatgtc 219180 acagaatttc aaggaagaga ggtgagcagc tgctgtggtg attttgaaat tgtttgtgtg 219240 tgttgtggcc agtgatgtca gaatttcagg atctgagagt tcatgatttt agaggctcaa 219300 aggagaatat ttttataact tttttctata atttttttat aattttttta tatatttttt 219360 ataatatttt ataatttttt ttgctatgtg agtatcccta ctttgttcaa ggaatctcat 219420 tatcttttcc ctttttttaa aaagggattt ttttgtagta acctgaataa attgggggaa 219480 gtattgatat atttcctttt ctcaccattt tttgttggat gaaaataatc ttttagtgaa 219540 attcagtgta ttaaatattt attttttaaa gtctagagat ggggtcatgc tgtgtttccc 219600 aggctgccct tgaactcctg ggctcaagca atcatcttgc ctcaacctcc tgagtagctg 219660 ggactacagg catgtgctgc catgcctggc ttaaatattt aaaaaatttt atctggcaca 219720 ttctgaacac agatgtttct acttatattt gtcatgtagt cacagtatat attgattttg 219780 ctacctcgcc tactcctaaa agttttaatt catttaattg gtcttaattg gacttaaaaa 219840 ttttttccct ggccgggcgc cttggctcac gcctgtaatc ccagcacttt gggaagccga 219900 ggcaggcgtt tgagaccagc ctgaccaaca tggagaaacc ctgtctctac taataataca 219960 aaattagctg ggtggggtgg cacatgcctg taatcccagc tactcaggag gctgaggcag 220020 gagaatcact tgaacccggg aggcagaggt tgcagtgagc tgaaattgtg ccattgcact 220080 ccagcctgga caacaagagc aaaactctgt ctcaaaaaaa aaaaaattcc caatagattt 220140 taatctaatt ttattagaac aattcagtca tatgtttttt catgctatgt atatgagagt 220200 tccattattc agatactaaa caaatgtcta ctgtacattt actcttctca ctgatgatgg 220260 attagataac catgcacaaa ataagcctgg ctgtggaaat gcttatttgt tgggagggtg 220320 cttgtttgga tcgatgatga gaataattgt ctgaggatgc tgagggactc attccagatg 220380 tcaatctgag gtccagatgt gtggccctcc aataggacaa ataagactct cagagcctgg 220440 ctctatttgg ggatccctca gtgacaacat agtacctctg tgagcgtgcc ttttctatct 220500 ctccgaagag ggcattagca tcctgtctta tgagtcagta tgcactttag tatggttagt 220560 gacccaagac tcactttatt ttgttcattt tgagcagaga attgtagata gatacatata 220620 tgggaaatat gttcttgatt aacaaatgaa aaaatgaaaa agtttcagtc aagaaaggtc 220680 aaggaactgt gatgtatagt gaaggcaggg aacactgcat gcctgtatta aatattgaca 220740 aaggaaccaa ttttagtgct ttgttatttt tactgttgag tattttctga gaccatttct 220800 ttttcttcta ttttgttttg ctgaggtaga ggagggctgg aatgaggtcc tccacttcag 220860 aaaatagggg tgagtagtta aaccaacatc ctttggaatt catatacgtc atgcgttcca 220920 tgccacatcc tgagatcttt ttgttgattt ttttagtggc ttactggata atatctaaat 220980 actgtatatt ttactttggt gagtctctcc accttcattt ctgaatcatt gtcctttaca 221040 tttttattct atttgaattt tgcatgaaat gacaaatgta gaattttgcc caatttattt 221100 tatttattca tttatttatt tgggaagaca aagtctctct ctgtcaccca ggctggagta 221160 cattggccca gtcagagctc acttcagctc ttcaccctgt agcccttaac tcctgggctc 221220 aagtgatcct ccaccctcag cctcccaagt atctaggaat acaggtatgt gttaccacac 221280 atagctaatt tttaaatttt ttattttgtg aagataggat cttactgtgt tgctaaggct 221340 ggtcttgaac tactgggctc aagcagtcct cttgttttgg cttcccaaag tgctaggatt 221400 acaggcagga gccaccatgc ctggcatcat tagggatatt ggtctgtgat tcacttttga 221460 tgatgtcttt ggttttgata aaaattaggg taatagtaga ctcatggaat aagttgggaa 221520 atgttttctg ctctcctgtt ttttggaaga gttgtgaagg attgatgtta tttctttaat 221580 gatttggtag aattcatcag agaaatcatt tgtgtggaat tttatttgtg gaaacttgag 221640 tagctaattc aatctcttgt taaaggtgac ttcaattttc tgtttttcct tcttgtgaca 221700 gttcctgtaa tttatatatt tctaggaatg tgcctattta atctaggtta tgtaatttgt 221760 tgacataact tgtttatata agggtgttag tctgattttc atcccagatt ttatgaaaat 221820 tgggtcttct gttttcagta gtgtagatat agttatgtca attttttaag agacagagtc 221880 ttactgtgtt gtttatgctg gccttgaact tctgagccta agcaatcctg ctacctctgc 221940 atcttgagta ggtgggagtg tgggaacaca ccaccacacc tggcctgtca ctaaacaaac 222000 aaaaaatttc agtgaaccag cttttgatat ttttattttt cttctgtatt ttttatttta 222060 tttattggca ttttattctt atatctttta ttctacttga tttagctttg ctttgttttt 222120 ctgttttctt aaggtaaaag tttagattat tgatttgaga ttttcctttt tttaatatgg 222180 acatttacag ctataaattt cccaaagaac tcttttagct acatatatat tttcttttgt 222240 tgtgttttgt ttcctttgat ttcaaactat tttataaatt ttcttatttc tcccaagaac 222300 tcccaatgat tcttagtaat gtgttaattt ccatatattg tgaattcccc ccaatttttt 222360 tcctttattt ctgatatgat tctattgtgg ttggacacca tacttttctg atttctttac 222420 tttcagattt gttgatacca gtgtgtggtc taatacctac cctgcacact gttccatgtg 222480 cacttgaaaa taatatattt tctactggtt agattgttcc atagatggat gttatgtaac 222540 tgttttatag tgttgtttgt cttctatttc cttgatcttc tgtctcattg ttatgttcat 222600 cattgaaagt gaggtattga aattttcagt tattataatg tttattttgc cttccattct 222660 gtcattttta aaatttaatt tgggggttat gttgttggat gcacgtatct ttattattgt 222720 tatatcttcc tgatggattg acagtttaat catcatgaaa tgtcctttgt ctctaccaac 222780 aatttttttt tttttgagat ggagtctcgc tctgttgccc aggctggagt gcagtggcac 222840 catctctgct caccacaagc tccgcctcct gggttcacac cattctcctg cctcagcctc 222900 ccgagtagct gggattacag gcacctgtca ccacgcctgg ctaatttttt gtatttttag 222960 tagagacggg gtttcaccat gttagccagg atggtctcga tctcctgacc tcgtgatcca 223020 cccacctcgg cctcccaaag tgctgggatt acaggcgtga gccaccgtgc ctggccctct 223080 accaacaatt tttatcttga aatttattta gcctgataat tgtagttttt gtctgactta 223140 tagcccataa actctctctg gttactgtat gcagtttatc ttgtcattat tttactatct 223200 acctattttt aattaaaaca aaatatcttt gagacaggat ctcactctct cacccatgct 223260 gtagcgcaat ggcatgatca tagctcactg caacctgaaa ctcttgtaat tcaagcaatt 223320 cttccacctc agcctcctga gtatctgaaa ctacaggcca acaccaccac acctggctaa 223380 tttttttgta ttttttttct tgtagagatg aaatcttggt atcttgccca ggatggttat 223440 tttctaccta ttttttgtcc ttgaatctaa agtgtatctt ttgtagagag catatagttg 223500 tatcatgtgt ttttttaaaa agatacatct ctgcctttta agtggagagt ttacttcatg 223560 aacatttaat gtaattactg ataaggtaaa attcacatct gccattttct attttctttt 223620 atggcatata tctgttttgt ttttcttatt gttctttatg ttaaataagt aatagtgtac 223680 tgctttaatt ttctttttaa ttttttgtgt ttacttatta gtggttgcct ttgagattat 223740 agttaatttg ttaatttata atatagctta gatttaatag ttaattttaa tagtacacag 223800 aaactatttt tcaatatagc tctgttttct cacccttcct tttgtatatt attgtcattc 223860 aaacatttat accatctttt atatttgcct aataattatt ttactggtcc tgtgcatttc 223920 ttcatatgga tcaaagttaa tgtctagtgc tatttcactt aaggctgaag tctccattta 223980 atttttctgg taggataggt attttgacaa attcagcttt tgttggttta gaatgtcatt 224040 tcttttttat ttttgaagag tacttttgct gtttcaagat ctatgggtag acagtcttac 224100 ttctttttct ttaaaatagt ttgaatatgt tatcttactg ttttatggct tcaagagttt 224160 ctgatgagaa atcagctgtt agtctcattg aggattcctt gtacctgatg ggtttgtttt 224220 tctcttcata ttttgaagac tggcttttga aatttttact atgacgtctc catgtcttta 224280 tgtgtatctc acttgagtga gtcaagttca tttgactcat tttatatgta catgtatgtt 224340 tttcccttac attaaggaaa ttttaggcgt ttgttcttca aactgtttct gcccttctac 224400 tgtgactttt atgaacatgt tgatatgctg tgttcctcag ttctctgaag ctgtttttct 224460 tttttctttc tgcttcacag aatggatctc ctcaactgtc ctgtattcaa attcgattac 224520 cttttcctgc tagctcaaat agtgtgatta aatttttcta gtgaattttt attatttatt 224580 tctctgtatc tttattgtct agtaattgat acatttttaa aaaatttaaa ttttaggttt 224640 aggagtacat gtgcaagttt gttatatagg tagattgtga gtcatgttgg tttggtgtac 224700 agattatttc attacccagg taataagcat agtacctgat aggtagtttt ttgatcctca 224760 ctctcctccc accttctacc ttcaagtgct cccagttaca agagagaatg tatggcattt 224820 agtttactgt tcctgcatca atgtgcttag gattatggcc tccagctcta ttcatgttgc 224880 tgtaaagaac atgatttcat tcttttttca tggctacata gtattccaag gtgaaaatgc 224940 tccatatttt ctatgtccag tctaccagtg tgatagttaa tattgagtgt caacttgatt 225000 ggattgaagg atgcacagta ttgttcctgg atgtgtctct gtgaaggtgt tgccaaagga 225060 gattaaaatt tgagtcagtg aattgggaga gacagattca ccctcaatct gggtgggcac 225120 aatctaatca gctgcacagt ctcatcagct gctggtagaa taaagcaagc agaagaatat 225180 agaaggacta gactgtctga gtcttccagc cttcatcttt cacccatgct agatgcttcc 225240 tgcccttgaa cattggactt caagctcttg tactcttgga cttacaccag ttgtttgcaa 225300 ggggctctca ggccttcagc ccacactgtt ggcttcccga cttttgaggt tttgggactc 225360 agactagctt ccttgctcct cagcttgcag aggaactatt atgggacttc accttgtgat 225420 tgtgtgagtc catcctcctt aataaactcc cttttatata tacatctatc ctattagtcc 225480 tgtccttctg ggaaaccctg actaatacaa ccagtcctgg gtacctgggt tgattgtatg 225540 tctttgctct tgtgaatacc acagtgatga acattgaagt gcatgtgtct tttggtagaa 225600 tgatttattt tcttttgggt atataccaga aatgggattg ttgggtgaaa ctgtagctct 225660 gttttaagtt atttgagaaa ttctcagact gttttcctca gtgaccggac taatttacat 225720 tcccaccaac agtgtttaaa cattcccctt tttcttcagg cttgccagga tctttctctt 225780 ttttgctttt aataatagcc attctgacgt tgtgagatac tatcttattg tggggttttt 225840 tttgttgtcg tcgttgtttg tttttcgaga cagagtcgcc cagggtggag tgcagtggtg 225900 tgatctctgc tcactgcagc ctatgcctcc cgggttcaag cgattctcct gccttagagt 225960 cccaagtagc tgggactgca ggcgtgtgcc accatgcctg gctacttttt gtatttttag 226020 tacagatggg gtttcaccat gttggccagg ctggtctcga actcgtgacc ttgagtgatc 226080 caccaccatg gcctcccact gctgggatta caggcatgag ccaccgcatc gggcccttat 226140 ggtggttttg atttgaattt ctctgatgat tagtgatact aagagcattt tttcatatgt 226200 ttgttgacca ttctatatct tcttttgaaa agtgcctctt aatggggttg atttttgctt 226260 gttgatttat ttaagtgccc tatagattca ggatattagg cttctgtcaa atgcatagtt 226320 tgtcaatgat ctctgttcgc caatgatatg gttctatacc tagaaaatgc cttctttaag 226380 aaaataaaat tgtattttgt ggatgtatca cattttcctt atatatctgc tttgggcatt 226440 tgggttgctt ctgcctcttg ggcattatga ataatgctac agtgaatatg gatatgcaga 226500 tgtatgtttg agatcttgct ttgaattact ttggatatat acccaaaagt gggattcctg 226560 gatcatatgg taattctatt gttaattttt caggaacctc catacatttt tccacaatgg 226620 ctgtaccatt ttatgttccc atcaacagca tgcaaaggtt ccagtttctc cacattgtca 226680 ccaacacttg ctgtttttta tttcactctt gttgcccagg ctggagtgca atggcactgt 226740 cttggttcac tgcaacctcc acctcctgag ttcaagcgat tctcctgcct cagtctcccc 226800 gagtagctgg gattacaggt gcctgccacc atgcccagct aatttttata tttttagtag 226860 agacagggtt tcaccatgtt ggccaggctg gtcttgaact cctgacctca ggtgatccac 226920 ctgccttggc ctcccaaagt gctgggatta taggcctgag ccaccacgcc tggctcgttg 226980 tttttcaatt gtatcttcta atggatgtga ggtgatacct cattatggtt ttgatttgca 227040 tttgtttagt aattagtgat actgagcatg ttttcatata cctgttgtcc atttgtttat 227100 cttctttgga aaaaaatcta ttcaattact ttgccccttt tttaaaatta gggttttttg 227160 ttgtaatctg agtttgttcc ctccctccct cactctctcc ctccctctct tccctccttc 227220 cctccctcct tccttccttc cttccttcct tccttccttc cttccttcct tccttccttc 227280 cttcctttct tccttccttc cctccctccc tgtctccctc cctgtctccc tccatgtctc 227340 cctccctgtc tccctccctc cctcccttct tttctccctt cctccctccc ttcctccctc 227400 cctttctccc ttcctccctt ccttgatcac atccacatcc ttccttcctt cgtgctgtgt 227460 tgctcagcat ggagagcagt gccaaaatca tggctcactg cagcctcaac tttccaggtg 227520 ccagagagcc tcccacctcg tgctcgtggg accacaggca catgccaaca cgtctagcta 227580 attgtttttt aatttttatt ttttggtaga tatgggggtc tcactgtgtt gcacaggctg 227640 gtttcaaact cataggctca aggaatcttc aaaccatggc ctctcaaagt gttgacatta 227700 caggcatgag ttaccatgcc catcctgcat gtgaaagcct tacgagatat gatatgcaaa 227760 tatttctctc atttggtacg tttcctcttt cattctgttg attgtttccc ttcatgtaca 227820 aacattttag gtttgatgta gtcttgcttg tctgtttttg cttttgttgg ttatactttt 227880 agtgtcacat tcaaaaactt attgacaaaa acaagaaggg tttccatgtg ttttcttcta 227940 gttttacaat gtcaagatgt atctttaagt acttaattta ttttgagttg atttttgtgt 228000 atgttgtaag gtaaggattc agtttacttt ttttttttaa tttgcggata tccagtatgc 228060 caaatatgat tagttagata aactgtgctc tgagcaccca tgtcaaagat aaattgagta 228120 gagtacatgg atttatttct gcattcttca ttcttttcca ttagattatg tctgtttttt 228180 gccagtattc tagtattttg aattactata gctttgttat atacttggaa atcaagaagt 228240 gcctccacct ttgtgtttca tgctgaatat tgatttagct attttggttc ttttgtggat 228300 ccagataaat tgtatgattt ttttctctat ttctggaaaa atgtgattgt gattttgata 228360 ggaattatag tgaatcagta gataactttg ggtagtatgg atattttgac aatattaatt 228420 agtcccagtg gtggtgttga ggccgtgttg acctggaggc actggggtca gtgatagtgt 228480 tgtcaagttg gctgcaggat gggatggtgc ctgggaggtc agtgcataaa aatcctatgg 228540 atgtgatcaa ggaaagggtg atggaaggtg atgtgtcctg tctgcttggt ccttgtagga 228600 tcaggcagga catcctgtaa taaaaggaga cattaccttc ggatgtcctg agggcatggt 228660 gcaggcacca ggactgagtg gaggggagga agctcatgtc ttgaggtcct ttggctacat 228720 ggggaagact gtctctgggc ttgatgctga gttccagact gacgtgctgg ctgttgtgat 228780 ggtgctctcc agtgctggtt gtggttggtt tttggctagg tacacctcac ctgggacagt 228840 ggccaaagac agtgtcagtt ccagacatca gaagccccat gaggaagagc atgtgctcgc 228900 gccaggagtg gtggctgtta ggggagggac ctcagaccta tgtctgcatg gcctgaggtc 228960 agagttcaca tcctactgat tgaagacctt gttcttgagc tgtccggttg ccacagggtc 229020 ggacctggag gctgcagacc atcgtggccc tttgcagtgt tcggaaacat atgcgcaccc 229080 cagggaggga cacacacaca cacacacaca cacacacaca cacacacaca cacgcaaact 229140 cacaaacaca acacacagac agaaaatgac aaataaacac acacactcac acacacacac 229200 acaggagccc acagaaaaaa gcaaatagac gcagaaacgg gcacgtgcag tagttctggc 229260 cacacatgtt ccctaggtat ccacagaatg gcatgggtat tgtatattca taaagatgga 229320 gatcagtcat ggaggccaag gacaagtagg tgcactggtt gaactacagt agagaatggc 229380 atggaagtgg tgagcaatgg acctgggcct gtttctcaag tgtgtatttg atttctttac 229440 aattccccgg agaagttgtc atgggaggcc agccgcctgc tggcaaggaa gatggttgat 229500 tcttctgatc aatggaggcc ctgcagagtc ctgtagtcac tgtggcctgg catccatggt 229560 gcacccaatg ctggtggatg gcttaggacg gtaagcattc ctctgcccca cgtgctgaat 229620 gagagtggct tttggatgtc ctataccttc aaggagctgt ttgtcagcag cgaatgacat 229680 ggcaagttcc actcctagag tggatggtct gtgcccattg ctcagtggtg cagctctggc 229740 ttccccagca tgctgaatgt ctttaaggtc atcagctcgc cccttcccag cctgtggtgt 229800 caaatgtctt gccccttgtc aaatgtgctt ggatcgatga tgagtcccct ataaaaacat 229860 tccttggaaa agctgaacaa aatgagtgag aactcataac gtcattctca tcggaactga 229920 ggtccagcat gttgcttcct ctggggcctg taggagtgag ggacaacttc cactgattcc 229980 cataggttcc accacccagg gcatccacag acaaaagtct cgtgtcacag gcacgttagg 230040 aacattccct ctgtgtgagg tacatgggtg ggagagtgat gggggattcg gccgctctgt 230100 gatggcgtgg tggccgtgga agcaggcaga aatgttgcag gcctagggga agtggaaatg 230160 ttgccagcac aggggtgtgt gctactggta agctcccaga aggaagaccc ggacctcaca 230220 gtggtcatct cagtgcagaa gaccaggtgt ctgttttcat gtcgaggaga gcccaaggcc 230280 cagacctcag gcagaccttg gtgttgattt ttgattagtt gagaacaggg gagtgccaag 230340 gtgttagggg agagtgcaga gcaataggtg tcggggcaaa cagtgaaagc ctcttcagcc 230400 taccctgcag cattggtcac caggagccct cctggaaggg atttctttgc ctcctgagct 230460 gtgagatgcc tgtggtgcag tggcagaggc ctaggtagga aggtactcca ggggaaaggt 230520 ggtagaggga tcacatggac atgagtgtca ttagcaggct tgggctgtca ttcaggggtg 230580 atgggcttcc catggatttt tctggtggaa gacaggttgg ccagcagggg tcttcgaggc 230640 caggtcctgg ggagcacgag gatcgagttg gtgcccgtgg ccctgggtca cttccagtct 230700 tcccaggaga gtaatgggct cctccattgt gcaaatcttc ctataaatgg tctcttggcc 230760 cgccattatt gggcggctcc acctgctgca gcttgtatga gcaaatactg ctctggatcc 230820 tctttcctgc ttggaaagca gcttcagtcc tgaaggtcca gagtgaatgt gccctgaccc 230880 tggctctggc ccaagtctgt gccgtaggta ctcgtcacac ttggagctat ccatggaggt 230940 ctgtgtgcat tccaggcaac acgggtgcaa tcccaggggt gctgccacag agtcctttta 231000 cttgggatgc ctcacacctc tgcatgttgg caatatttaa gtgttggagt ccactacacc 231060 ctaggggtga tgaactgttt tggctccctt aaccggtttg aagtctcagc gcagccagga 231120 cagccatgcc atgttgaagg gcatgcagat ggcttaggaa tgttggaaag gatgggtggt 231180 tctgagctcg cagctcactc actagctgca tgcatgtaga cccagtggtg gtgttcaggt 231240 agtgttgact ttgaggcatt gcggcgggta gtagtgcagt caagttggct gcataatggg 231300 atgttgcctc agaggtcagt acaggatagc cctgtgggtg tgtccaatgc aaggaaaatg 231360 aaaggcagtg tatcccatcc gcctggtcct tgggacatcg gtagggggga cgtcccattg 231420 gaaaagcagc cattccgttt gtgtgtcgag agggcatagt gcaggcacat ggactgagtg 231480 gaggggagga aggctgtgtc ttgaggtcct ttggctagat tgggaagacc acctctggcc 231540 ttgacgccaa gtttcaggct gatgtgctgg ccattgcaaa ggcgccctcc agcacaggtt 231600 gtgattggtt ttccaccagg tacgcctcac ctgagagggc ggctagagac agtgtctgct 231660 caggacatca gatgtcccgt gaggaggagt gtgtactcac accaggggag ttgactggta 231720 ggcgagccac cttgggccta tgtccgcatg gtctccaggt caaaattcac atcctactga 231780 ttgaaggcct tggtcttcag ctgttgggtt ggcgtggtgt caggccagga ggctgcagac 231840 tatgactgcc tgttgcagtg ttgggaaaca cacatgttag gaaacacatg tgcatgaggg 231900 agacacacac acacacattc atacacacac acacacacac acagaggcat gccgagccac 231960 aggcaaatac atgcagcaat gggcgtatgt gaccacgtgc acttttaggt atccacagag 232020 taacacatgt aagatatatt catggagatg gaggtcagtc gtggaagcca aggaataacg 232080 ggtgtgcaag ttgcccaacg ggaaagaatg ggattgaagt gttgaccagt ggacctgagc 232140 ccatttctca agcgtttatt tgatttcttt acacttctca gaggcagttg ctgtgggagg 232200 tgtggtaact gctggaagga agatgctcaa ttcttctgag caacgaaggc cacacggagt 232260 cctggattct gtgtggcctg gcatccatgg cgcactgtgt gctggcaggt ggctcaggac 232320 ggtaagcatt tctctgccca gtatgctgaa tgagggtgtc tttcggattt ccaagacccg 232380 caaggagcag tttctcagct aaccactaat ggcatggcga gttcctctcc tagagtggat 232440 agtctgtgct cattgctcag tggcatcgct ctagtggggc cgaaggtctt taaggtcatt 232500 ggctcaccca ctgcccagcc tgtggtgtca aatatcctgc cccttgcccc ttcaaatgtg 232560 cttggatcga tgatgagtcc ccaaaaaaaa cattccttgg aaaagctgaa caaaatgagt 232620 gaaaactcat accgtcattc tcatcggaac tgaggtccag cacgttgcct tccccgggga 232680 ctgtaggagt gagggacaac ttccactgat tcccataggt tccaccaccc aaggcatcca 232740 cagccaaagt ctcccatcaa atgctcatta ggaacattcc ctttttgtga ggtacacagg 232800 taggagagtc ctggggggaa cggctgctct gtgatggcct ggtggccatg gaagcagaca 232860 gaaatatcgc aggcctaggg tagtgtgcgc ctgatcttgg cttggtgagc tcctaggaag 232920 ggagacgcgg acctcgtggc aggcgtctct gagcagagga ctgagtcctt gttttcttgc 232980 cggggagagc acaaggccca ggcctcaggc agatgttggt cctgattttt gattagctga 233040 ggacaaggga gtgccaaggg tgatggggga cagtgtataa caaagggtgt tgtgacagag 233100 agccaaagcc tctttggccc tccacccagc atccagtcat ggaggccccc cagcagggat 233160 ttcttcatcc cctgagccgt gagatgcccc tggtgctatg gtggaagcct ggactggaag 233220 gtactccaca gaagaggtgg tagggggctt atgtggacat gtgtgtcatc agcagtcttg 233280 ggctgttgtt cagcgttgat gggctttcca tttatttctc tagtggatga caagttggcc 233340 agcagaggtg tcagagggca ggttccaggg aatacaaggg tcagacttgt gctcctggcc 233400 cttggtcact tctcgtcttc ctgacagagt agtgggctcc actgttgggc acatcttcct 233460 ggaagtcgtc tcttggcccg ccattgccga gcggccacac ctgctgcagc tcgtgtgagc 233520 aaatatggct ctggatcctc tttcctgctt tgaaagcagc ttccatcctg aaggcgtcca 233580 gagggtatgt gtcctggccc tggccaggaa ctctgctgtg ggcattggtc acacgtggct 233640 atccatggag atccgggtgc attccaggca acattctagg ggcctgccat ggagagttcg 233700 ttgacttggg atgcccctgc acctcccatg ttggtgatgt tccagtgttg cattctgcta 233760 caccctaagg gtgatgaagc atttcagctc ccttaaacag tttgatgtca cagtgcagcc 233820 aggacagcca tatcatgttg aggggcccac gactgcatta ggaatgttgg aagggattgg 233880 tggttctgca gatcgcagct cattagtagc tgtttacttg tagacctggt gatggtgctg 233940 aggcagtgtt gacttgcagg agttgggatg ggtggtaatg cagtcaagtt ggctgcatga 234000 tgggatgttg cctcagagtt ctgtgcagag aagccctgtg ggtgtaacca gtgcaaggac 234060 catggaaggc agtgtgtcct gtcaacctgg tccttgggga agggacgtcc tgttggaaaa 234120 cagccattcc cttcggttgt cctgaaggtg cagtgcgggc atgtggactg agtggaggaa 234180 gcccgtgtct tgagatcctt tggctaggtt gggaagattg cctctggctt gatgccattt 234240 tcagacctat gggttggtaa ttgtgaaggc gccctcacgt gctggttgtg gttggttttc 234300 cgccaagtga gcctcacctg ggagtgcagc cagagacagt gtcaggtcac aacatcagat 234360 gccccatgag gaggagcatg tgctcactcc aggggtggtg gctgttaggt gagggacctc 234420 aggcctatgt cctcctggcc tgattttaca tcctactgat tgaagacctt ggtcttgagc 234480 cttcgggttg caggggcttc aggtctggag gctgcagact atggcctcct gttgcggtgt 234540 tgggaaacac atgtgcatga gggaaacaca catacactat cacacacaca aacaggcgct 234600 cacagccaca ggcaaatata cgtagcacca cgtgcgtgtg gtcgttccgg ccacacgtgc 234660 ttcctaggtg tctagaaagt gacacagtca gatacattta taaagatgga ggtccataat 234720 ggaggccaag gagaagcggg catgtgtgtt gctctgtgga agagagtggc gttgaagtga 234780 ccagtgaacc tgggcccatt tctcaagcat gcatttgatt tctttacact tctcaggggc 234840 agttatcatg ggacacccgc catatgctgg caaggaagat ggtcagttct tctgagccac 234900 aaaggccccc aacatcctgg agttggtgtt gcctagcatc cacggtgcgc cccctgctgg 234960 tggatggctc aggatggtaa gcattcctcc gccgcacatg ctgagtgggg gtgggatttc 235020 caagacctgc aaggagctgt ttctcagcag gccactgatg gcatggcgag ttccactcct 235080 aaagtgaacg gtctgtgccc attgttcagt ggtgcagctc tggcttcccc agcgtgcgga 235140 gggtttttaa ggtcatcggc ttgcccactg cccagcctgt ggtgtcaaat atcctgcccc 235200 ttcaaatgtg cttggatcga tgatgagtcc cccataaaaa cattccttgg aaaagctgaa 235260 caaaatgagt gagaactcat accgtcgttc tcatcggaac tgaggtccag cacattgcct 235320 cccccgggga ctgtaggagc gagggacaac ttccactggt tcccagaggt tctaccactc 235380 agggcgtcca tggatgaaag tctcacatca caggcacaat agaaatattc cctctgtgtg 235440 aggtatacaa gtaggagagt catgggggga ttggctgctc tgtgatgtcg tggcaactgt 235500 agaagtgggt ggaaatgcag acctagggga gtgtgcggct ggccttggct tggtgagctg 235560 ccaggaaggg agaccctgac ctcctgatgg gcctctctat gtggcggacc aggtcttttt 235620 tttatgccaa ggagagcaca aggcccagac ctcagacaga ccttggtctt gattttcagt 235680 tatctgagga gaggggagtg ccaaagtgat gggggacagt ggagagcaat gggtgttgtg 235740 gcagacagcc aaagcctctt tggccctccc cccagtgttg gttacagggg cccctggcag 235800 caatttcttt ggctcctgag ccatgagtta tccatggtgt ggtggctcag cctgggcagg 235860 acagtacccc agagaaaagg tggtagaggg ctcacatgga cacgcgtgtc atcagtggtc 235920 ttgggctgtc atttggcagt gatgggcttt ccatggattt ctattgtgga tgacaggtta 235980 gccagtgggg ccttcaaggg cagatccaag gagcatgagt gttgggctgt agcccgtggc 236040 cctcggtcac ttctggtctt cccggcagaa tagtgggctc caccgttgtg cacatcttcc 236100 tggaaatggt ctcttggccc tccattgctg agcagcccca catgctgcag ctcttgtgag 236160 caaataactg ctttggatct tccgtcctgc tttgaaagtg gcttccatcc tgaagacttt 236220 cagagggaat gtgccctggc cctggccctg gctcggaact ctcctgtggg attcggtcac 236280 acttggagct gtccatgggg gtctgtgtgc agtccagaca atgcatattt aatcctaggt 236340 gccttccata gagagtccct tgatttgagt tgcctctact cctctgcatg ttggtgatac 236400 tcaagtgttg gatttagcta cgccctaggt gtgatgaact gtttcaaccc cgttagtctc 236460 agcgtagcca ggatagtcat gccatgttga agggcatgca gatggcttag gaaagttgga 236520 aaggattggt cattctgcgg ctcgtggctc acttagtagc catgtgcatg tagacctggt 236580 ggtggttgtc agatgtcgtt gagcaggtgt tggggaggat ggtcctgcat ccaagttggc 236640 tgcgtggtgg gatgttgcgt cggaggtcgg tgcaaggaag gcctttgagt gtgatcgatg 236700 caaggatgat ggaaggcact gtgtcctgtc tgcctggtgt ttggggcgtt aggcagggat 236760 gtcccatggg aaaagcagcc attccctttg ggtgtcctga ggacatggtg caggtacatg 236820 gactgagtgg aggagaggaa gcccgtgtct tgaggtcatt tgcctaggtt gggcagactg 236880 cctgtggcct tgatgctgag tttcagagtg acgtgctggc cgttgcaaag gcgccctcca 236940 gtgctggttg tgtttggttt tgtgccaggt gtgcctttcc tgggagtgct gccagagaca 237000 gtgtctggtc acgacatcag atgccccgtg aggaggagct tatgctcagg ctagggatgg 237060 tggctgttat gtgagggccc ttgggcctat gtctgcatgg cctcgaggtc agagtttaca 237120 tcctgctgat tgaaggcctt ggtcttgaat tgttgggttg gtaggggctc aggtctggag 237180 gccgcagact atgactgcat gttgccatgt tgggaaactc gtgttgggaa acacatgtgc 237240 atgagggaga tacacacaca cacacacaca cacacacaca gccactcagc aatgtgtgtg 237300 tgcgcggtcg gtctggcgcc acacacagct ccaagctgtt tgcagagtgc cactggtaag 237360 gtacattcat ggaaacagag gtcactcatg gaggccaaca gaagcaaggc gtgcaagttg 237420 ccacgcatga aagaatggca ctgaagtagt gaccagtgga cctgggcctg tttctcaagc 237480 gtacatttga tttctttata cttctcaggg gcagttgccg tgggaggccc gctgcctgct 237540 ggaaggaaga tggtcagttc ttctgaacca caaaggccct gcagagtcct ggagtctgtg 237600 tggcctggct tccagggttc acctcatgct ggtggattgc tcaggatggt aagcattcct 237660 ctgccccatg tgctgagtga cggtgtcttt tggatttcca agacccataa tgagctgttt 237720 ctcatgaggc cactaatggc atggtgagtt gcattccttg agcaaatggt ctctgccttt 237780 tgctcagtgc catggttcta tcttccccag ggtgccgaag gtctttaagg tcgtcagctc 237840 acctactgcc cagcctgtgg tgtcaaatgt cctgcctctt caaatgtgtt tggatcgatg 237900 atgagtcccc ccaaaaaaac attccttgga aaagctgaac aaaatgagtg aaaactcata 237960 ccgtcgttct cagcggaact gaggtccagc gcgttgcctc cagcagggac tgttggagtg 238020 agggagagct tccactagtc cctataggtt ccaccaccca gggcatccgc aggtaaatgt 238080 ctgccatcac acgcacatta ggaacattcc ctttgcgtga gatacactgt taggagagtc 238140 acggagggat tggatgctgt gtgatggcgt ggcagctgtg gaagtggacg gaaaaatctc 238200 aggcctagag gagtgcgtgg cactgatgag ctcccaggaa gggagacccg gaccttgtgt 238260 caagcttcct cgcacacagg accgggtcct ggttccccta ctacagagag tatgaggtcc 238320 cagcctcagg cagaccttgg tcttgatttt cagttagctg aggacagggg agtgccaagg 238380 gtgatgggga agagtgcaga gcaatgggtg ttgtagcaga tggccaaagc ctcttcggcc 238440 cttcccccag cgttggtccc agggtcaccc cagcatggat ttctttgcct cctgaaccgt 238500 gagatgccca tggtgtggtg gtggagacct gggtaggaca tattctctgg tattccagag 238560 aaaaggtggt agggggctca catggacagg tgtgccatca gtggtcttgg gctctcattt 238620 ggtggtgctg ggctttccgt gtattcctct gatggatgac aggtcgggca gcaggggtct 238680 tcaagggcag ttcccaggcg tgtgagggtt gggctgctgc ctgtggccct gggtcactcc 238740 gatcttcctg gcagagtaat gggctccacc gttgtgtaca tcttcctgta aatagtctct 238800 tggcccgcca ttgccaggcg gccccacctg ctgcagcttg tgtgagcaaa tactgctctt 238860 gatccttttt cttgctttga aagcagcatc cgtcccaaag gcatccagag ggaatgtgcc 238920 ctggcccagg cccaggaccc tcccgtgggt tccaatcatg catggggctg tctgtggagg 238980 tccgtgtcca ttccgggcaa tgcgtgtgca atcccagggg tgttgccacg gaaagtctct 239040 tgacttggga tgcctccacg cctctgcatg ttggcaatgt tccagtgttg gattccgcta 239100 ctccctatgc atgatgaagc attttagctc ccttagccag tttaaattca cagtgcagcc 239160 aggacagccg tgccactttc aagggcactt ggttggctta ggaaagttgg aaaggattgg 239220 tggttctaca gttctcagtt cacttagtag ctgcatgcat gtagacctgg tggtgctgat 239280 gcagtgttga cttgccagtg ttggggtggg tagtagtgca gtcagattgg ctgcatgagg 239340 ggttattgct tctgaggtcg gtgcagggat gccctgtggg tgtgtccaat tgaagaacga 239400 tgacaggcag tgtgtcctgt caacctggtc cttgggaatt caggtaggga cgtcctgttg 239460 gaaaagcagc cattctcttt gggtgtcctg agggaacggt gcgggcacat ggactgagtg 239520 gaggggagga ggcatgtatc ttgaggtcct tttgctaggt tgctagtcct acctctggcc 239580 ttgatgccaa gtttcagact gacatgctgg actttgcaaa ggcgccctct ggagctggtt 239640 gtggttggtt ttccgccagg tgcacctcac ctaagagggt ggccagagac agtgtcttgt 239700 catgacatca gaagccccat gaggaagagg aggagcctgt gctcctgcca gaggtggtgg 239760 ctgttaggta agagacctgt gacctgtttc cacatggccc ggaggtcaaa gttcacatcc 239820 agtgatcgaa ggccagggtc ttgagccatc ggattgctgg ggggatcagg tctggaggct 239880 gcaaactaga actgcccatt gtggtgttgg gacccacatg tgcattaggg agacaaacat 239940 gcccatttaa actaacattc tcacacatgc acacacccac acccacccat acacacacac 240000 tctcatacac tcacactcaa actcacactc tctctttcac acacacacac acacacacac 240060 aggcacagac agccataggc taatagatgc agcgatgtgc acatggtgtg gttctggcca 240120 catatgcttt taggtgtcca cagagtgacg caggtaaggt atattcatgg agctggaggt 240180 cagtcatgga ggccaaggag aagcaggtgt gtgagttgcc ctgtgggaaa gaatggtgtt 240240 gaagtgtcca gtgaacctgg gcctgtttct caagcatgca tttgatttct ttacacttct 240300 cagggacagt tgccgtggga ggtccgctgc ctgctgtcaa ggaagatggt cgatgcttct 240360 gagaaacagg ccctgcgggt tcctggattt ggtgtggcct ggcatccacg gtgcaccccg 240420 tgctggcggg tggcccagga cggtaagcat ttttctgccc cgtgtgctga gtgatggtgc 240480 ctttagaatt tctgagacct gtgagcaaca gtttcttggc aggccattaa tggcatggcg 240540 agttccattc ccaaagtgga tggtctgtgc cggttgttca gtggcgcggc tctggcttcc 240600 ctagggtgcc aaagttcttt aacgtcatcg gcttgcccac tgtctggcct gtgggtgtca 240660 aatgtcccac ctcttcaaat gtgcttggat cgatgatgag tcccccataa aaacattcct 240720 tggaaaagct gaacaaaatg agtgagaact cataccgtcg ttctcatcag aactgaggtc 240780 cagcacgttg cctcccgtgg ggactgtagg agcgagggac aacttccact ggttcccata 240840 ggttccacca ccgaggacat ccacaggcca aagtctccca tgaaatactc gttaggaaca 240900 ttccctctgt gtgaggtaca tgggtgggag atttgtgggg gcactggctg ctctgtgatg 240960 gcgtggcggc catggaagag gggagaaatg tcgtgggcct aggggagtgt gtggctggtc 241020 tcagcttggt gagctttcag gaagggaggc ctggacctca tgggtggcat ctccatgcag 241080 aggacaaggt ctcacttttg ctaccaagga gagcacaagg tccaggcctc aggcagacct 241140 tgttcttgat ttctggttag ctgaggacag ggaagtgcca agggtgatga gggagagtgt 241200 ggagcaatgg gtgccacggc agatggccaa tggctcttca gccctcctgc caatgttggt 241260 cacagtgtcc ccccagcacg gatttctttg cctcccgaaa tgtaagatgc ctgtggtttg 241320 gtggtgaagg tgtaggcagg gtggtattcc agagaaaagg tgctagaggg ctctcgtgga 241380 catgagtgtg cattgggctt taatttggca gtgataggct ttccatggat ttctctggtg 241440 gatgacaggt cagccagggt gggtctttga gggcatgtct ctgggtgagt gagtgtgagg 241500 atggtgtcca tggccctggg tcacttctgt tgttcccagc agagtagggg gctctactgt 241560 tgtgcacatc ttcctggaaa tggtctcttg gccttcgttg tcgggtggcc ccacctgctg 241620 ctgctctcgt gagcaaatac tgctctgtat cattcccgct ttccatccca aaagtgtcca 241680 gagcgaatgt gccctgtccc tggcctggga ctctcctttg ggctccagtc atgcatgagg 241740 ctacccgtgg agatctatgt gcattctgag cagtgtgttt gcaatcccag gggcattgcc 241800 acagagagtc ttgacttggc atgtctccat gtgactgtgt gctggcgatg ttccagtgtt 241860 ggactccaaa agtccctagg cgtgataaag catttcagct cccttagctg gtttgaagtc 241920 acagagcagg caggacagcc atgccacttt caagggcata cagttggcac agaaaaattg 241980 gaaaggattg gtggtcgtac atcttgcagc tcacttagta gctgcatgca tgtagaccgg 242040 gtggtgttga tgcagtgttg acttgctggc attggggtgg gtggtagcat ggtcaagctg 242100 gctgagtgat gggatattgt ctcagaggtt ggtgcaggga aactctgtgg gtgtgtctaa 242160 tgcaaggata atgacaatgt cctgtctgcc tggtctttgg ggggtcaggt ggagatgtcc 242220 ttttggaaag gcagccattc tctttgagtg tccagagggc atggtgcagg cacatggatt 242280 gagtggaggg aaggaagcgt gtgtcttgag gtcctttggc taggttggga agactacctg 242340 tggccctgat gctgtttcag agtgatgtgc tggccattgc aaaggcgccc tccagtgctg 242400 gttgtggttg gttttccatc aggtgcacct cacctggtaa aggggccaga gacagtgtct 242460 ggtcatgaca tcagatgctc tgtgaggagg agcatgtgct cgtgccaggg gtgctggctg 242520 ttaggcaagg gaccttggac ctctttcctc atggccttga ggtcaaagtt cacatcctat 242580 tgattgaagg ctggggtctt gagtctttgg tttagtgggg ttggttccgg tctggaggct 242640 gcagactatg actgcccgct ggggtgttgg gaaacacatg tgcattaggg ggacacacat 242700 ccacacagag acacactcat gcacacatgt gtgcacagcc acagacaaat agatgcagca 242760 atgggtgtgt gcaatcgtta ggccacacac acttataggt gtccatggag tgacacaggt 242820 aaggtatgaa tgggtctttg aaggcatgtt tctgggcgag tgagtgtcgg gatggtgtcc 242880 atggccctgg gtcacttctg gtcctcccag cagagtagtg gtatgaatat ggagatggag 242940 gtcagtcata gggtccaagg agaagcaggg gtacgagttg ccccgtggga aagaatgaca 243000 ttgacgtggt gaccagtgga cgtgggccta tttctcaagc gtgcatttga tttctttaca 243060 cttttcaggg gcagttgcct tgagaggccc accgcctgct ggcatgacag atggtcagtt 243120 cttccgagca gtggaatctc catggagtcg tggagtcggt gtggcctcgc atccacagtg 243180 caccctgtgc tggtggatgg ctcaggacag taagcattcc tctgccccgc atgatgagtg 243240 agggtgtctt tagaatttct gagtcccaca aggaagtttt tcagctggcc attaagggca 243300 ttgtcgaggc ctttaaggtc atcagctcgc acactgccca gcctgcagtg tcaaatgtcc 243360 tgcctctttg aatgtggttg gatcgatgat gagtcctcca aaaaaaacat tccttggaaa 243420 agctgaacaa aatgagtgaa aactcatacc gtcattctca tcggaactga ggtccagcac 243480 attgcttcct ctggggcctt tactagtgag ggacaacttc cactagtccc tataggttct 243540 aacacccatg gcgttcacag gtgaaggtct cctgtcatat tacaaacatt ccccccactc 243600 ccctcccaaa aaaaggaaca tttcctctgt gtcaggtaca caggtcagag agtcataggg 243660 tgactggctg ctctgtgatg gcatagtggc cgtggaagtg gatggaaatg tcgcaggctt 243720 aggggagtgt ggggctggcc tcggcttggt gagctcccag gaagggggac ctggaaatcg 243780 ctgcgggcat ccttgcatag aggaccaggt acgtgttcca gttctgcttt caaggagagc 243840 atgaggccca ggcctcagac agtccttggt cttgatcttt ggttagctga ggacagggga 243900 gtgccaaggg tgatagggga gagcgcacag caatggatgt tgtggcagac agctaaagcc 243960 tttctgtccc tcctttcacg gtcagtccca gggggccccc agcacagact tttttcacct 244020 ctcgagctgt gagattcctg tggtgttgtg gccaagcctg ggcaggaagg taccccagag 244080 aaaaggttgt agagggctca cgtggacatg catgccatca gtggtcttgg gctgtcattt 244140 ggtggtgatg ggctttccag ggatttctct ggtggatgac aggttggcca ttgggggtct 244200 tcaagggcag gtcctaggga gcatgagggt cgggctgatg cctgtggtcc tgggtcactc 244260 cattcttcct ggcagagtag tagaagtgtc catcttcctg gaaatggtct cttggcccgc 244320 cattgccagg cggccccacc tgctgcagct cgtgtgagca aatactgctc tggatcccat 244380 ttcccgcttt gaaagcagct tccatcccaa aggcgtccag agggaatgtg ccctggccct 244440 ggccctggcc tgggactctc cgatggggtc cagtcacact tggcgtattc atggaggtcc 244500 ttgtgcattc caggcaacac atgtgcaata ccaggggcac tgccgtggag agtctcttga 244560 tttgggatgc ctcctcgcct ttgtgtgttg gcgatgttcc agtattggat tctgctacat 244620 cctcagggca atgaagcgtt tcagctcact tagccggttt gacatcatag tgcagccagg 244680 acagccgtgc cacattggca tggcacatag ttgacttagg acagtcggaa agggttggtg 244740 gttctatgtc tcgcagctca cttcatagct gtttgcatgt aaacctggtg atggtgttga 244800 gatggtgttg acttgctgac gttggggtgg ttggtagtgc agttaagttg gctgcatgat 244860 gggatgttgc ctcagatgtc ggtgcagcga agccctgtag gtgtgtccaa tgcaaggaaa 244920 atgaaaggtg gtgtgtcctg tccaccttgt ctttaggggt tcaggcagga atgtcctgtt 244980 ggaaaactag ccattccctt tgtgtgtcct gaaggcatgg tgcgggcatg tgaactgatt 245040 ggaggaagga agtgtgtgtc ttgaggtcct ttggctgggt tcagaagact gtctctggcc 245100 ttgatgccgt gtgccgtgtt taagaccaac gtggtggcca ttgcaaaggt gccttccagt 245160 gcaagttttg gttggtttgg tgtcaggtgt gccttacctg ggagagcggc gagagacagt 245220 gtctggtcac gacattatat gccccgtaag gaggactgtg tgcttgcacc gccaggggtg 245280 ctggctgtta gtcgagggac atcaggccaa tgtctgtctg acccctaggt caaaattcgc 245340 atcctactga ttgaaggcct tgggtctcga gccttttggt tgcaggtgtg gggatggttt 245400 ccaggtctgg aggctgccaa ctatgacaac ccgttgtgct gttgggaaac atctgtgtgg 245460 gggagacaca tacacataga cacactcact ctgacataca cacctacaca tgcacaggcg 245520 tgcacagcca caggcagata gatgcagcaa tgggtgtgtg ctattgttgt ggtcacatgt 245580 gcttcctagg tgtccacaga gtgacatggg tcaggtatat tcatgaagat ggaggtctgt 245640 catggagccc aaggagaagc cggtgtgcaa gtttccctgt gggaaagaat gggattgaag 245700 tggtgaccag tggacttggg cccgtttctc aagcatgcat ttgatttctt tacacttctc 245760 agcagcagtt gtcatgagag gtctgccgct tgctggcaag gaagatggtc aattcttctg 245820 accaacagag gctgccttga gtcctgattt ggtgtggcct ggcatctatg gtgcacccaa 245880 tgctggtgag tggctcaggg tggtaagcat tcctctgccc tgtgtgcaga ggtgtctttt 245940 gaattttgag acctgcaaag agctgtttct cagcaggcca ctaatggcat ggcgagttcc 246000 actcccagag ctgattgtct gtgttcattg ctcagtggtg tggctctggg ttccccccag 246060 gatgctgaag gtgtttaagg tcatcagctc tcccactgcc cagcctgtgg tgtcaaatgt 246120 tctgcctctt cgaacgtgct tggatcgatg atgagtcccc cataaaaaca ttccttggaa 246180 aagctgaaca aaatgagtga gaactcatac cgtcgttctc atcagaactg aggtccagca 246240 cgttgcctcc tctggggact gtaggagcga gggacaactt ccactggttc ccatgggttc 246300 caccacccag ggcatttaca gatgaaaatc tcctatcaca tgcatgtgag gaacatttcc 246360 tctgtatgac atagacggat gggacagttg tggagggatt ggccactctg tgatgttgtg 246420 gcagccacgg aagcaggtgg aagtgttttg acctagggtt gtgtatggct ggtctcggct 246480 tggtgagctc ccaggaaggg agacccgggc ctcgcagcag gtgtctttat gtagaggacc 246540 aggtcacagt tcccctgcca aggagagcat gaggctcagg cctcagatag accttggtct 246600 tcattttcca ctagctgata atgggagttc caaggtgatg gaggagagca cagagcaatg 246660 ggtgtcaccg cagatggcta aagcctcttt ggccctcctt ccagcatcag tcacaggtgc 246720 cccctggcat ggatttcttt gcatccctag ccatgagatg accatggtgc agtgaccaag 246780 gcttggccag gatggtaccc cagagaaaag gtggtgaagg gctcatgtgg acatgtgtgt 246840 catcagctgc attgggctgt cacttggtgg tgatgggctt cccatggatt tctctggtgg 246900 atgacaggtc agccagggcg ggtctttgag ggcatgtctc tgggcaagtg agtgtcggga 246960 tggtgtctgt ggccctgggt cacttccggt cttctcagca gagtagtggg ctccaccgtt 247020 gtgcacacct ttctggaaat ggtctcttgg catgcattgt tgggtggcct tacctgctgc 247080 aactcatgtg agcaaataac tgctctggat cctctttccc gcttggaaag caatttccat 247140 tctgaaggca tccagaggga atgtgccctg gccctggcct gggattctcc agtgggttcc 247200 agtcatgcat ggggctatcc acggaggtct gtgtgcattc caggcaatgc gtatgcagtc 247260 ccagcggcat tgccacagag agtctctcga cttgggatga ctctgcgtgt tgacagtgtt 247320 ccagtgttgg attccgctat gccctaggcg tggtgaagca tttcagctcc cttaactggt 247380 ttgaagtctc agcacggcca ggacaggcat gtcacgctga agggcacaca gttggcttag 247440 gaaagctgaa aaggttggta gttctacggc ttgcagttca cttagcagaa acgtgcttgt 247500 ggaccccgtg gtgttgagac agtgttgact tataggcact gtggtatgta gtagtgaggt 247560 caagttggct gtgtgatagg atgttgcctc agaggtcggt gcagggaagc cctgtagatg 247620 tgtccagtgc aagaatgatg acaggcggtg tgtcctgtca accttgtcct tagggggtca 247680 agtggagatg tcctcttgga atagcagcca ttagctagga tgtcctgagg gcacggtgtg 247740 ggcatgtgga ctgagtggag gggaggaagc ccgtgtcttg agattgtttg gctaggttgg 247800 gaagactgcc tctggccttg acactgagtt tcaaactgag gtgctggact ttgcgatggt 247860 gccctccagt gctggttgta gttggttttc caccacatgt gcctcacctg agagggcagc 247920 cagagagagt gtctggtcac aacatcagat gccctgtgag gaggagtgtg tgctcatgcc 247980 aggcttggtg gctgttaggc aagggacctc gggcccatgt ccgcatggcc tcaaggtcaa 248040 agttcacatc ctactgattg aaggcctggg tcttgagctt ttgggttgtg aggaggttca 248100 ggtctagagg ctgcagacta tgaccacccc ttgtggtgtt gggaaacata tgtgcatgag 248160 ggagacacac atacacacac acacagacac actctctctc tcacacacac acacacacac 248220 acacacaggc gtgcatagcc acaggcaaat agattcagca atgggcacat gctgtcgttt 248280 cggtcacaca cgcttcctag gtctccacag agtgacacgg gtcaggtata ttcatggtaa 248340 tggaagtcaa tcatggaggc caaggaaaag taggtgtgtg agttgccctg taagcaagaa 248400 tggcgttgaa gaggtgacca gtggaccttg gtctgtttct taagcatgca tgtgatttct 248460 ttacacttct aaggggcagt tgccgtggga ggcctgccgt ctgctgaaag gaagatggtt 248520 gatgcttctg agcaatgaag gccccatgga gtcctggatt cggtgtggcc ttgcatccgt 248580 ggtgcacccc gtgctggtgg atggctcagg acggtaagca ttcctctgcc ccgcatgatg 248640 actgagggtg tctttaggat ttctgagacc cacaaggagc agttcttcag caggccatta 248700 agggcatggc tgtggtcttt aaagtcattg gctcacccac tgcccagcct gtggtgtcaa 248760 atgtcctgcc tcttcaaatg tgcttggatc gatgatgagt cctccaaaaa aacattcctt 248820 ggaaaagctg aacaaaatga gtgagaactc ataccgtcgt tctcatcgga actgaggtcc 248880 agcacatttg cctctgccgg ggactgtagg attgagggac aacttccact agttcccata 248940 ggttccacct cccagggcat ccacaggcca aagtctccca tcacacacag gttaggaaca 249000 tttcctctgt gcgatgtaga cgggtaagag agtcatgggc aaattgtctg ctttgttatg 249060 gtgtggcagc catggaagag tacagaaatt ttgcaggcct caaggagtgt gtggctggcc 249120 tcagcttggt gagctcccag gaagggagac ccagatctcg cggcagatgt cactgcacac 249180 aggactgggt ccgatttttt tgccaaggag agcatgaggt gtgggcctca ggcagatctt 249240 tgtcttgatt tctggttacc tgaggacaag ggagtgccaa gttgatgggg aagagcaatg 249300 ggtgtcccag cagatatcca aaggctcttt ggctctcctt ccagggttgg tcacagggcc 249360 tccctggcag ggatttcttg gcctcctgag ctgtgagctg ctcgtagtgc aatggcagag 249420 gcctgggcag gaaagtattc cagagaaaag gtggtagagg gctcacgtgg acatgtgtgt 249480 catcagtggt ctggggctgt catttggcag tgatgggctt cacatggatt tctctggcag 249540 atgacagctc agccagcagg ggtcattgag ggcaggtcac agtgaacatg agggtcaggc 249600 tggcacccac agcccttggt cacttctggt cttcacggca gagtagtggg ctccactgtt 249660 gtgcacatct tcctggaaat ggtctcttgg cccgccgttg ccggatggcc ccacctgctg 249720 cagctcgttt gagcaaatag tgctctggat ccactttccc acttggaaag cagcttccat 249780 cccgaaggca tccagaggga atgtgccttg gctctggctc tgccctgggc ctctcccatg 249840 ggctctagtc acacttgggg ctattcatga aggtctgtgt gtattccaga ttccaggcaa 249900 catatgtgca atcccaatgg cattgccaca gagaatcttt tgacttggga tgcctccgtg 249960 ccactgtatg atggcgatat tcaagtgctg gattctgctc catcctgggg tgatgaagcg 250020 tttcagttcc cttagccagt ttgaagtcac agtgcagcca ggacagccat gccacattga 250080 cgggcttgtg gttggcttag gaaagttgga aaggattggt ggttctacag ctagcagctc 250140 acttagtagc cacatgtatc tacacctggt gctggtgttg aggtggtgtt gacttgcagg 250200 cattgttgtg ggtgggaatg cggtcaagct gactgcacga tgggacattg cctctgaggt 250260 cagtgcaggg aagccctgtg aggtgaccag tgcaaggaca atgttaggtg gtgtgtcttg 250320 tccactcggc ttttggggca tcaggcgtgg acgtcctgtt ggagaagcag ccattctctt 250380 caggcatcct gagggcacgt gtgcgtacgt ggactgagtg gagtggagga agctgtttct 250440 tgaggtcgtt tggctaggtt gggaagacca cctctggctt tgacgtcatg tatcagtgca 250500 acattctgag cattgggcag gtgccttcca gcacaggttt tggttggttt tccgccagat 250560 gtgccttacc tgggagtgca gcaagagaca gtgtctggtc ccgacatcag aggccctgtg 250620 aggagtagcc tgtattcgcg ccaggggtgt ggtggctgtt acacgaggga catcaggcct 250680 atttccacgt ggccttgaga tcagagtgca catcctactg attgaaggtc ttgaaccttt 250740 gatttgttgg ggggatcagg tctggaggct gcagactata accgcccatt gcagtgggaa 250800 tctcacacac acacacacac acacacacac acacacgtgt gcacagccac aggcaaatac 250860 tcgcagcaat gggcacatga ggttgttcca ggcacacaca cttcctatgt gtccacagag 250920 tgacagaggt aagatacatt catggagatg gagatcaatc atggaggcca aggagaagca 250980 ggcatgcaag ttgccccaca ggtaagaatg ggtttgaagt gaccagtgga cctgggccca 251040 tttctcaagc atgcatttgg tttctttaca cttctcaggg gcagttgcca tgggaggcgc 251100 aggcctgctg gaaggaagat ggtcgattct cccaagcaac aaaggccacg tagagtcctg 251160 gtttcagtgt ggcctggtat ccacagtgca ccccgtgctg gtgggtggct caggacggta 251220 agcattcctc tgcccttcgt gctgagtgag ggtgtctttg ggattcccaa gacccacaat 251280 gaacagtttt tcagtaggcc actaatggca tgctgagttc ctctcctaga gtggatggtc 251340 tgtacctttt gctcagtggc acagctctgg gttccccagg gtgccgaaca tgtttaaggt 251400 catcggctca cccactgccc agcctatgat gtcaaacatc ctgcgtcttt gaatgtgctt 251460 ggatcgatga tgagtccccc ataaaaacat tccttggaaa agctgaacaa aatgagtgag 251520 aactcatacc gtcgttctca tcggaactga ggtccagcac attgcctcca ctttggctta 251580 ttgtggttca cgggtaactg tcatattaca tggtacttca ctacccaggc actggcattc 251640 aatttttgtg gtcgttttga ccatagtaaa attctttatc ataaatgtat ttgagaatca 251700 tacttgggta gcccatgaat ttttttagtg ttactcttct tggtgtcaag ttggtttcac 251760 ccttaatgct aggttttgga tttttgttgc atgattgatt tttagccagg ttctggtcac 251820 caatcacagc ctttcaccaa cattcatgga gaaagtttcc ttgttttttt tatatgttga 251880 ggaagtacat atttcctgaa tgtttttgct tttgttccaa tgttgggctg actggcatgt 251940 catctcttat cttatcttga actgagtagt ggtacaagtt tttggctttc agcatccagg 252000 gcaccaagtc ttttgtacac aaattgcaag tattgaagcc atggtgttga ttgggatgct 252060 ctacgcccat actctttagt ggcatgacgc cctcccaggg tacccggaat ccacatgtgc 252120 aactctgtat atgtgtttct gtgaacacag atatgtgaag ccatagataa gcagatttca 252180 tatgtaccac aggagtctat atgacatagc cttcctgacc tatgtacctg tctgtctttc 252240 tgaagcacac tcatttcctc tgcaccttcc tggtgtcatt ggcatggaag gaaggccctt 252300 gtccaagaag gatggtcttc gtcttgtgtg atctttgaga tgccatgagg cccctggata 252360 caaatggtgt gggctccttt ggaggctttt ggatttctcc tgaatgtaag tgatttcttc 252420 tgaaagcatt ctgattttcc tcacttgcag ggacaaagac tatgtgtagg ttgatgatga 252480 cttacatata tacgtttttt tttttttttt ggaaaggtga acaaaatgag tgaaaactca 252540 gtaccatcat cctcatctaa ctgaggtcca gcacgcttct ccatcagggc ctagatttag 252600 ggggccaaca tctgtttgtt atcatggtgt gcaccaaggc ttaggatgta gttgtctttc 252660 agtgaaactg agtagctgag tattttgtac tcccctggct gagagatacg tttgttgaac 252720 gacttacctg tgagaaggtg gggtagcatc ctgccagtgt gcaggagaag gtaaacctgc 252780 aggtgccaca ggaaggcggt atccagttgc ccacctctgc atggctgggt ctgtccttga 252840 ttcatacctc ttgggttcgt caccccccag aagaagacaa tttattccac atgaggagac 252900 agcacggtgc cattcctgag cacttcttca actgtctttc atctgtggcc ggggacatgg 252960 gacttcttat ggtgtttggg tagcatcaag ggctggccat cttgaagcca gtggtgatgc 253020 tgatttgctc tctggaaagg agcctggaga agctctctac agtgaacttg tacatctata 253080 agtagaattc caaatttcat ggcccaagaa gggtagtggc tgtgggaagg ggagaggtct 253140 gtgtgtgcct ttacctggca tcattccatg tgggtcgtgg agtgatgact gtgaggctct 253200 ttaagacatt gcagggtgcc caaggtccat ttcgtgatat cctcaggatg gtttgcttgg 253260 gagagcctga tgtcatttgc ctctgaaccg ctcagacatc ttgatgcagt tggggtttat 253320 aagagtgtgt cattccccac atcgtggtga cttctacttg gaaatgtgac ctgcgaaggt 253380 ctccttgctt atatacctca gcgtctcctg atattagggt attttcaaat tcctcctaat 253440 tcttcacagc agtcttcttt gtgaaatagt cgttgtgtgg taggacaggg ctaccatcca 253500 caggccaatg atggataggt gttggactct gatgttatgt tcacaggcaa gtgccttaag 253560 atcttgtttt cttagctgca gcaccttaga aatcttgtag gattcagaat gcctggtgct 253620 cttctgggtc cctgatctgt acctgtgtag tgcacatgga ggttgatttg tgatgtttct 253680 ggatgggaag agtgtgaagg acccaagggg taaaaatgcc tcaaggccaa aggaaagtta 253740 acctttgcat aggaagaggt ttcccctcca aactctcctc actgaagtat caccatagcc 253800 tttgtcttct ctgatggcca ggagaagggt ttttgagttg gaggtgttat aagagtggtg 253860 ttgagagtgt tcttcatgct tagtgctctc tagttgatgg tgccttcaaa attcatgcct 253920 gcctcctacc ttcatgtttg ggcaaaccca tgcatgtgtg cagaaagaag gggagcccat 253980 gggaggtaga tacagattac tccacaacag gacaaatgac atgacccttg ccacctatgc 254040 acctcactgc ctttctcaag cacactgttt tgcttctgca cttcttaggt ggcgttggta 254100 tggaaggaag gccagtgacc gcaagggatg actttgatct tgggagattt ttggagatgg 254160 caaagtgctt ctaaacatgt ttggcatggt ctccttcagg ctggtggata cctcaggatg 254220 gtaagtattg gttttccaaa ggcacctaat gttccatgtt tgcaggtatg aggactgtgc 254280 atggatcaat gatgacttcc atacgtgggt tccttggaaa gttgaacaaa atgagtgaaa 254340 actttatact gtcatcctct tcaaactgag gtccagcaca ctgcttcaac aggggctaga 254400 gatggaggtc tacctctcat tcattgacgt gggttgcacc aaggggtctg tccaggctta 254460 ggatggggtt ctcttttggc aaggggtagc cccaggggag tgggagctcc catgcacagg 254520 agattcctgg tgtgaaggac atctcttagt gaggccaggg tagcacacac accatcttca 254580 agactaggtg aatgtgcagg tgacacaaag gacttaggct ctgtgtcccc cagtttgttc 254640 ttgagtctta gttcttggtt ctctcatcat cgggaggaag gcaggtcctt ctcgttggga 254700 agagaggaca agcctacact tttgcctcat ttttggctca tttttatcct tgtgtatgta 254760 catagatttc tggtcacctg catgcttcac atccaggcca gagtgcctct gttgtaccct 254820 ctgtgttatg aagacataca gttggcctcc tgccctaagc tggggctgat aggcaacgag 254880 tctctggctt atctcaaacc tggtgtaggt caaaggcttc ctcgttaggg gtgcaggtcc 254940 ccgaggcttt tatgatcaac tttgcaggtg tgcacgggtg tttaaaggga tgctcaacat 255000 cagttctctc tagtgggatt atgtactcca tgggctccca ggatccagac gtgcatccct 255060 gtgtctatgc agttctgcgt ccataaacag gtgaagccag agatgggcag attgcagatg 255120 tactgcaggg ggccagatgg catggccctc ataacctctg cacatgtctg cctttctcaa 255180 acatgcccat gtttcatctg tacctcccag gtggcgttgg catggaagga aggactgtgt 255240 ctgtgaggga tgatcatcct ctcatgtgat ccttggagat gccaggaagc cccttgacac 255300 atgtggcatg ggctccttca gaggcttttg gatccgtcgt gaatgtaagc aagcccttcc 255360 caaagccctg attttcctca tttgcagaaa caaagattgt gcctggatca atgatgactt 255420 ccatatatac attccttgga aagctgaata aaatgaatga aaactctata ccatcatcct 255480 cattgaactg aggtcccagc atgctgctac attggagggc aaggagaggg ggccaacatc 255540 tgtttgttga catggtctac accttggctt aggatgtggt cctctttggg caaatgcaag 255600 cgtctgggct ttttggactt ctgtagctga gagacagctt ggttgaagga atttcctctg 255660 agaaggtggg gtaagcacac tgccagcctg cagaacttga agctgcagat ggcacaggaa 255720 gcagtagcca gtagtctctt tgtgcatgac tgtgtgtgtc cttgattcat agctttttgg 255780 tttgtcgcct ccccgcttgc acaggaatac cattgctttc ctttggggag agagcatgtc 255840 attcctggac acttgttcgg cttactttca ttctcagtcg aggatgtggg agttcccatg 255900 gtacttgggt agcatcaggg gcaggcagcc atgaggtggg tggtgagctg atttgctttc 255960 tgcagaggag cccagggagg gtatccacat tgaactcgta tgtccatagg aggaaaccca 256020 agtcctttgg tccctgcagt gtactggtgg tgggaagggg agagggctgt gcatgcatgt 256080 accaagcgac attccatgtg ggtcgtggag caatgactat gagcctcttt tgggagttgt 256140 agggtgccca tgctccattt catgatgacc ttggggtgct gggatgggaa tgagattgca 256200 agtccctgtg ttcctgccac ttcgcagact gacttggttt gagagatctg tgttcaggaa 256260 cccctgtggg atgcttgtct gtgttaggca tttgagcaga tattggccca gggtttctac 256320 ccttccatgg ttgtacatac tgctggaagg gcttgttgct ccctctgtat tgatgagggg 256380 aagttttgcc caggagagcc tgatgccatt tgcttctgaa ctgctcaggc acttcaatgc 256440 agttgaggtt aagagtgtgt cacttcccat gtcgtggtag catctactca gaaaagtgac 256500 ccgtcaaggt ctctgcactt aaattctcca ttatcttatg atgttaggtt attttcaaat 256560 tcctcctaat tcttcacaac agtcctcttt gtgaaacagt catgaagttg tatgagggct 256620 gtcatccaca ggccagtgat ggagagtttt gtactctgtg gccatgttca caggcaagtg 256680 gcttaagacg tatcgtgttc tcagggacag caccatagaa gccctgtagg attcagcatg 256740 tctgatgctt ttctggttcc ctgagctgca cctgtgagga aggccagagg tggaggttga 256800 tgtgtgattg aatgtgtttc tcaatgcaaa gtgtgtggaa ggagcttcaa ggccgaagga 256860 aagttgttct ttgtgctgga acactttttc cctgcagctc tccccattga aatatcctca 256920 tggctgttgt cttctctgat ggccaagaga atggcttttg agtcaggggt ggtgaaagtg 256980 tggtattgag agaattcttc gcgcttagtg ttctctagtt tgatggtgcc cttgaaatgc 257040 atgcctgcct tataccttca tgcctgggta tatctgtgca taagtcccca aagagaggtc 257100 acccatggga ggtagatata gaatacagca tggcaggagg aatggcatgg cccttgcaaa 257160 ctgtgtacct gcctgccttt ctcaagcaca cctgtttttc ctctgcactt cccaggtggc 257220 atgggcatgc aaagaaagac agaggctgca agggataaac ttcatcttgg gagatccctg 257280 gagatggcag ggaacccatg gacacatgtg gcatgggctc ctttgggtgc cggtggatcc 257340 cttcatacgg tatgtgttca tttctcaaaa gaccctaatg ttcttccttt acaggaatga 257400 atactgtgca tggaccaatg atgacttcca tacatgcatt ccttggaaag ctgaacaaaa 257460 tgagtgggaa ctctgtacta tcatcttagt tgaactgagg tccaccgggg gctatagagg 257520 gacaactgtc attttttttg atgcccgttg catgaagcat tcttccaggc ttaggaaggg 257580 attccgtttg ggtgaaggag agtcacaggg gagttgaggc tatgtgcaca ggacttctgt 257640 ctacaaggct ggggtagcac acatgcagtc cgtgggacta ggtgaatgtg caggttgctc 257700 agggagagtt aacctgtagc ctgcctctgg gtggccaaga ttgtccttga ctcctggctc 257760 tgggttccca caacccctgg aggaagacaa gtaattgtgc ttgggaagag agaacaaggc 257820 catacttttg cctttctttt tttcattctt agtttgagaa cagtggagtt ccaatcacct 257880 ggcatagctt tcatgttgtg ttccatgcat tgtgagtaca tgcatatggc aggaacacac 257940 aggttcccac tgcaagctga gcctgatagg caaggagtct ctagcttaac cccagcccag 258000 tgtacgtcaa tggcttcctc attaaaattg catggccctg tagcttttgt gagtgacatt 258060 ataggtatcg atgtaagggt gttgagaggg atgctcaatg tcagtgctct ttagtgtgct 258120 gatgcactac tacaagggca cctgagccct tgtccatgca tttctgtgtc caaaatcagg 258180 taaagccaga gttgggtatc aaccagatac actgcagggg atcagaggac atggcctttg 258240 tgtactgcac atctgtcaga ttttctcaag cacacccgtg tttcctcttc acctcccacg 258300 tggaagtgat gaattggcca ggaccatgtt ggtgagggac aatcatcatc tcatgttaac 258360 ctcagagaag ccaggaagct cctggacaca catggtgtag gcttccttgg aggctgttgg 258420 atctctcctg aatgtaagca attccttccc agtgcaccct gattttcctc atttgcagaa 258480 acaaagattg tgtgtggatc gatgatgact tccatatata cattccttgg aaagctgaac 258540 aaaatgagtg aaaactctat accgtcattc tcgtcgaact gaggtccagc acattactcc 258600 aacaggggct agacagagag ggccaacatt gattcgttga catgggtggc accaagggga 258660 ccatccaggc ttaggatggg gtttctttgg gtgaatggta gacacagggg agtaggatct 258720 cccatgcaca ggacatacct tgtttgaagg acttctgtgt cctagggctg gataactcat 258780 gtgctgtctg gaggactagg tgaatggcag attgcatggg aagagttaac tggtagcctg 258840 cctctgatgg ccaagtttgt ccttgagtcc aagctctggg taccgaagtc ccccagagga 258900 agacagatcc ttctggttgc ggggagagca aaaggctaca cctttgccat tagttggctc 258960 attttatcct tagctgagga tgttggagtt gtgtttaccc ggcatagcct ctgtgcctat 259020 gtgcccatgt tgtgtactgt gcattgtgag gatgtatatt tggcatgaac aggcaggctt 259080 cctctccaaa ctggggctga tagacagcga ggctctgggt tatcccaaac cagatacagg 259140 tcaatggctt cctctttagg ggtgcagggc cttgattatt ttgtgactgg cattgcaggt 259200 gttgaaacaa gggtattgag aaggatgctc aacatcagtg ctctttagcg ggatgatgca 259260 ttctgagggc tgccatcccc aagatgagca tacttgtgtc cataaatttc tgggttcacg 259320 aacaagggaa gccagagaca ggcatattcc agataaacca cagggggaag atagcatggt 259380 cctcgtgacc tgtgcacccg tctgcctttc tgaagcatgc ttctttatcc tctgcacttc 259440 gcaggtagtg ttggtgtaaa aggcaaaccc gtgtcatgag ggatggtcat catcttgtgt 259500 gatccttgga gatggcagga agccctggac atacatggtg tgggggctcc tccagaggct 259560 gttgggatcc tcctggatgt aagtgattcc atttcaaagc accctgagtt tcctcatttg 259620 cagggatgga gattgtgtgt ggatcgatga tgacttccat atatacattc cttggaaagc 259680 tgaacaaaat gagtgaaaac tctataccgt catcctcgtc aaactgaggt ccagcacact 259740 gctccatcag gggctcgaga gagaggaaca acatccattt gttgacacag actgcaccaa 259800 ggcttggggt ggggtctttt tctggcagag gagagtagct gggaattttg gacgtttgta 259860 actaagagac agcttggttg aaggcagcca ggtgtgtcgt caatttgtac cttgggtccc 259920 ttgtcctcca gaggaagact attgcttcca catggggaga cagcacaagg tcattcccag 259980 acacctcttt cactcacttt catccttgtc aagggacgta ggacttccca tggtgtttgg 260040 atagcatcag gggcaggcag gcagtcttca ggaggatggc gatgctgatt tgctttctgc 260100 agaggagccc agagagggta tccacactga acttgtatgt ccataggagg aaacccaaac 260160 cgcatggtcc cagaagggtc ctggtggtta gaaggggaga aagctgcaca tgcatttacc 260220 acacagtctt ctgtctgggt tgtggagaga tgactgtgag cctcttttgg gtgttatagg 260280 gtgcatacgg tttattttat gatgatcttg ggatgctggg atgggaatgt aattgcgaat 260340 ccatgtgttc ccgcaactcc acagacttga cttggtttgg caggtttgtg ttcaggccct 260400 ctgtggaatg cttgtcttca ttaagaattt gagatggggc tgggcacggt ggctcacacc 260460 ttctgggtgc ttgagctgca cctgtgagaa agaccccgag gtggaggctg aattgtgatt 260520 gagcatgttt cttgaatgtg aagtgtgttg atggatgctt gcagtaaaaa tgcttcaagg 260580 ctaaaggaaa attgccctat gcacaggaag agtttttttt ttcccaaaac tctccccatt 260640 caaatatctc tatggtctct gtcttctctg atggccaagg gaagggcttt tgagtcgggg 260700 caccaaatga gtggtgtcca gagttcttca catttagtgc tctgaagctt gctggtgccc 260760 tcaaaatgta tgtgtgcctc aaaccttcat gcatgggtac tcccatgcac acatcctgaa 260820 atgggtatcc catgggaagt agcgataggg tatcccacag ggggttgaat ggcatggccc 260880 ttgtgaccta tgtgtttgcc tgcctttctc aagcacaccc gtgttgcctc tgtacttcct 260940 aggtggtgtg ggcatggaag gaaggccagt ggagacaatg gatgatcttg ttcttagcag 261000 atcactggat gtggcaggga gtcctaggac atgtgtggtg tgggcttctt caggtgctgg 261060 taagtatcta ttccccaaaa ccccctaatg ttactccttt gtgggcatga agactgtgca 261120 tggatcgatg atgactttca tacatgcatt ccttggaaag ctgaacaaaa tgagtgaaaa 261180 ctctataccg tcatcctcgt cgaactgagg tccagcacat tgctcttaca ggggctggag 261240 tgagggccaa gtttcatttg ttgctgcagg ttgcaccaag gggtttgttc agttgtagga 261300 ggggctccct ttctgcaagg ggtagtcaca gggttgtgag atctctcata aataggaaat 261360 tgttttaggg acttctctct gcaaggtaac acacacacac cgtctgtagg actatgtgaa 261420 tgtgaaggtg acatgggaag acttagcctg tagcctgcct ctggtggcca tatttgtcct 261480 tgagtcttag ctctgggttc catcattccc ttgaggaaag acaggtgttt gtgcttggga 261540 agagagcaca aagccccacc tttgctgttt tttccactca ttttcatcat tgttcaagga 261600 cattgcagtt ccggttttat ccataaccag ggaagccaga gacaggcaga tagcagatat 261660 gccatagggg gccagatgac acggccctca tgacctgtga atgtgtctgc ttttttgaag 261720 cacactcgta tttccgctgc acttcccagg tggtgttggc atgaggaaag gaggtatctt 261780 cgagggacaa tcttcttctt gtgcgatcct tggagatgcc atgaggcccc tggacacatg 261840 tggtgtgggc tcctttggag gctgttgtat cccttctgaa tgtaagtgtc cactttccaa 261900 agtcctgatt ttcctcattt ttgggcatga ataatgtgca tggatcgatg atgacttcca 261960 tatatacatt ccttggaaag ctgaacaaaa tgagtgaaaa ctctataccg tcatcctcgt 262020 cgaactgagg tccagcacac tgttcatcag gggctagaga gagagacaac atccatttgt 262080 tgacacaggc tgcatcaatg cttgggatgg gatcgtcttt gggtgaagtg gagtagctgg 262140 gcattttgga cttctgtggc tgagagacag cttggttgaa gctcttccct ctgtgtggct 262200 atgtgtgtta tcgattcata ccccttggct cctgcactcc ccagaggaag acagttactg 262260 ctgcatgggg acacagcaca atgttgttcc caggcacttc ttcggctcac ttttatccta 262320 agtcggggac atgggagttc ctgtggtgta tgggtatcat caagggcagg cagtcgtgag 262380 gagggtggca atactgattt gctttctgca gagaagccca gagagggtat ccacgttgaa 262440 ttgtatgtcc ataggagggg gaaacccaag tcccgtggcc cctgaagcat cctggcagtg 262500 gaaggggaga gggccgtgca tgcgtgtacc acacagcctt ctgtctgggt cacagagcga 262560 cgactgtgag cctctttcgg gcattgtagg gtgcccatag tccatttcat gatgacctca 262620 gggtgctggg atgggaatgt aattgtaggt ccacgtgctc ctgcatctct gcagactgac 262680 ttggtttgga aggtctgtgt tgaggaacct ctgtgggata cttttccttg gtgcatttga 262740 ggtgtctgat aatgagtgtg tgggtttctg tatcctggtg acttctactc agaaatgtga 262800 cccagcaagg tctctgtgct taaatacctt agtggcttgt gatgttaggt tattttcaaa 262860 ttcctcctaa ttgtgtgtga caattcacac aagtctttgt gaaattgtcc ttgaattgta 262920 tgacagggct agtgtctgta ggccagtgat ggataagttt tggactccac agccatgttc 262980 acagccaagt ggcttaagat gtatggtgtt cttagtcata gtgccttgga agccctgtag 263040 gattcagcat gtcttgtgct cttctgggtc cccgagctgt acctttgagg aaaacccaga 263100 ggtggaggtt gatttgtgat tgagcatgtt tctcagtggg aagagtgtca aaggagcctg 263160 gggtgaaagt acttcaggac caaaggaaaa ttgcccttca ctcaagaaga ggctttcctt 263220 gaacctgtcc ccactgaaat atcctcatgg gcttcatctt ctctgatggc caaaagcagg 263280 acttttgatt cagaggtggc aaatgaatgg tgttgagaga gtttgttatg cttggtgctc 263340 tgtagctgga aggagccctc aaaattattg tgtgcatgat agcttcatgc ctgcttacac 263400 ccatgcacat gtcccagtaa gaggggctgc ctgtgggaga tacatacacg atacaccaca 263460 gtgggatgaa ttgtatggcc cttgcaatgt gtgtacctgc ctgctgttgt caaacacacc 263520 tgtttttcct ctgaactttc caggtggcgt gggcatagaa ggaaggccag tggccacgag 263580 ggacaatctt ggtcttggga gatcctggaa atgataggga gtcccttgat atgtgtggca 263640 tgggctcctt caggtgctag tggattcctt aggatggtaa gtgtccattt ctcagaagct 263700 ccagatattc ctcctctgca gggacaaaga ctgtgcctgg atcgatgatg acttccttat 263760 atacattcct tggaaagctg aacaaaatga gtgaaaactc tataccgtca tcctcgtcga 263820 actgaggtcc agcacattgc tcttacaggg gctagagaga gagggacaaa tttcatttga 263880 tgatgcccat tgcaccaagg ggttctgtcc aggcttagga tggggtctcg tttgggcaaa 263940 ggagaatggc aggggagtgg aggctatgta cacaggagat tccttgtttg aaggactcta 264000 tttgtgaggc cagggtacca cacatgctgt ccgcaggagt aggtgaatgt gcagttgccc 264060 aggaagagtt agcctgtagc ctgcctctgc atggcagttt gtccttgggt cctggctctg 264120 gatttccatg ttccttggag gaggataggt gattttgctt gagaagacag cacagtacca 264180 tacttttgtt gtttttctgc tcatttcatc gtccattgag gacaatgaag ttgtggtcag 264240 caggcatagc tttcaggcca gcgtgcccat gttgtgtccc atgcattgtg agcacatgca 264300 tgtggcatga acacataggc tgccactcca agctgagtct gataggcaat gagactctgg 264360 cttatcctga tcccggtgta gatcaaagtc ttcccagtag gattgcatgg ccccgaggct 264420 attgtgagct gcattgcagg tgtggaagca agggtgttga gagggatgct caacattagt 264480 gctctttagc gagatgatgc actataaggg caccctgaac ccagacgtgc atccctatgt 264540 acgtgcattt ctgtgtccat aaatagttga agccagacag ccagattcca gatgtatcgc 264600 agggggctgg atgacatggc ccttgtcacc tgtgtacctg tctgcctttc tgaagcacgc 264660 ttgtgtttcc tctacacctc ccaggtagca ttggcatgga aggcaggccc atgttggtga 264720 gggacaattg ttatcttgtg tgagccgcag ggataccagg aaacccctgg acacaaatgg 264780 caaaggcttc tttggaagtt gttggatccc ttctgcatgt aagcagttct ttcccagagc 264840 gctctgattt tcctcatttg cagggacaaa cactgtgcgt ggatcgatga tgacttccat 264900 atatacattc cttggaaagc tgaacaaaat gagtgaaaac tctataccgt catcctcgtc 264960 gaactgaggt ccagcacatt actccatcag gggctagaca gagagggcca acattcgttt 265020 gttgatatgg gttgcatcaa ggggtccatc caggcttagg atggggtccc tttgggcaat 265080 tggaagtcac agggaagtgg gagctcccat gcacaggaaa ttccttattt gaaggacttc 265140 tttctccctg ggcgggataa ctcacctact gtctgaagga ctaggtgaat ggcaggtggc 265200 atggaaagag tttgtgggta gtctgcctct ggtggccaag tttgttcttg agtccaagct 265260 ctggattccc agaggaagac agatcccctg gttgcgggga gagcacaagc ctacactatt 265320 ctcacttgtt agcttgtttt gtccttggcg gaggacgttg tatttccagg cacccagcat 265380 agcctctttg ccgcatttcc atgtcatatc ccatatgtta tgaggatttg tgtattgcat 265440 gatcaggcag gcttctgctc caagctgggg ctgtcaggca aggagtctct gggttattcc 265500 aaacctgatt taggtcagtg gcttcctctt tcaggattca tggccccaag gcttttgtga 265560 gcaccattgc aggtgttgaa gcaacgatgt tgagagggat gcccaacatc agtgctcttt 265620 agcaggatgg tgcacctcga gggcccctgg ccctgggacg agcatctgcg tgtccatgca 265680 tttctgtgtc catgaacagg cgaggccata gacaggcaaa tagcagatgt gtcacagggg 265740 actggataac atggccctcg tgacgtgtgc aacctgtctg cctttctgaa gcacgcctgt 265800 gtttcctctg cacttcacag gtggtgttgg catgaaaggc aggcttgtat catgaggaat 265860 gattgtcatc ttgtctgatt cttggagatg gcaggaagcc cctggaaaca catggtgtgg 265920 actctttcac aggctgttga aaccctcctg aatgtaagtg atttcattcc aaagcaccct 265980 gagtttcctc atttgcaggg atgaaacctg tgtgtggatc gatgatgact tccatatata 266040 cattccttgg aaagctgaac aaaatgagtg aaaactctat actgtcatcc tcgtcgaact 266100 gaggtccagc acattactcc aacaggggct agacagagaa ggccaacatc cgtttgttga 266160 catgggttat atcaaggcgt ctgttcaggc ttagaatgtg gtctcttatg ggtgatgggg 266220 gtcacaggag agtggtggct cccatgtata ggaaatttct tgtttgaagg actgtcagtg 266280 agggtgggta acacatgcat tgtctgcagg actaggtgaa tgtccatgtg gcctagcaag 266340 agttagctgg tagcccgcct ctggttgcca atttgttctt gagtccttgt tctgggttct 266400 caggtcccac ggaggaaaac agatctgtgt ggttgagagg tgggtacaag gccgcatctt 266460 tgtcatttgt tggctaactt tgtccttggt tgaggacatt agagttttgg tcaccaggca 266520 tagcctatgt gcctttgtgc ccgtgttgta tcccacgtgt tttgaggaca tgtattttgc 266580 acgtaaaggt gagctcctgc tccaagctgg ttctgatacc aaaggagtcc ctggcttatc 266640 ctaaactcat ggtaggttaa agccttcctc cttaggggtt cagggccgca aggcttttgt 266700 gagtggcatt gcaggcgttg aagcagtgat gttgagaggg atggtcaatg tcagtgctct 266760 ttagcaggat ggtgtactgc aggggccccc agccccgaga cgagcatccc tgcatccatg 266820 catttctgcc tccatgaaca ggggaggcca gagacaggca gatagtagat aaattgcagg 266880 ggactggatg acatggccct cgtgacctgt gcacctgtct gtctttctga agcacgcctg 266940 tgttaactct gcacctccca ggtagcactg gcatggaggg caggcacatg ttggtgaggg 267000 acaattgtta ccttgtgtga gctgcggaga taccaggaag cccctggaca caaatggcaa 267060 aggctccttc ggaagttgtt ggatcccttc tgaatgtaag cacttctttc ccagagcact 267120 ctgagtttcc tcatttgcag ggacaaatac tgtgcgtgga tcgatgatga cttccacata 267180 tacattcctt ggaaagctga acaaaatgag tgaaaactct ataccgtcat cctcgtcgaa 267240 ctgaggtcca gcacattact ccaacagggg ctagacagag agggccaaca tctgtttttt 267300 gacatgggtt ataccaaggc atccgttcag gcttaggatg gggtctttta tgggtgatgg 267360 gggtcacagg agagtggtgg ctcccatgta taggaaattt cttgtttgaa ggactgtcag 267420 tgagggtggg taacacatgc attgtctgca ggactaggtg aatgtccatg tggcctagca 267480 agagttagct ggtagcccgc ctctggttgc caatttgttc ttgagtcctt gttctgagtt 267540 cctggaagga aacagatttg tctggttggg aggagaatac aaggccacat ctttgtcgtt 267600 tgttggctaa ctttgtcctt ggttgaggac attagagttt tggtcaccag gcatagccta 267660 tgtgcctgtg tgcccgtgtt gtatcccatg tgtttggggg acatgtacat tgcatgaact 267720 agtgagctcc tgctcattgc ttctgatacc caaggagtcc ctggcttatc ctaaacccaa 267780 tataggttaa agcctttctc attaggggcc cagggtccca aggcttttgt gagtatcatt 267840 gtaggtattg aagcaacgat gttgagaagg atgctgaaca tgctctttag tgggatgacg 267900 tactctgaag gctcctgacc cccagatgag catccttgtg tccgttaact tctgtgttta 267960 tgaacaggtg aggccagaga caggcagaca gcagatgtat tgcagggagc tggatgacat 268020 ggcccttgga acctgtgcac atgcctgcct ttctgatgca cgtccatgtt ttctctgcac 268080 ctccccggtg gtgttggtat aaaaagcagg cttacatcag caagggatga ttgtcgtctc 268140 atgcgatcct gggagatggc agaagtcccg ggacacatgg agtgtgggct ctttcggagg 268200 ctgttggatc cctcctgaat gtaagtgatt ccttcttaaa gcatgctgat tttcctcatt 268260 tgcaggggca aggactggat cgatgatgac ttccatatgt acattccttg gaaagctgaa 268320 caaaatgagt gaaaactcta taccgtcatc ctcgtcgaac tgaggtccag catactgctc 268380 atcaggggct agagagaggg acaacatccg tttgttgaca agggctgtgt caacacttgg 268440 gatggggtcg tctttgggtg aagtggagta gctgggcatt ttggacttct gtggctgaga 268500 gacagcttag ttgaagcact tccctctgcg cagctatgtg tgtccttgat tcaaactcct 268560 tggctcctgc actccccaga ggaagacagt ggcttctgca tggggacacc acacaatgtt 268620 gttcctgtgc acttctttgg ttcactttca ccctcatttg gggacgtggc agttcccatg 268680 gtgtttaggt agcattgagg gcaggcagtc ctcaggagga tgttgatgct gatttgcttt 268740 ctgcagagga gccagagagg gtatccatgt tgaacttgta tatccatagg aggaaaccag 268800 tcccatggcc cctgaagggt cctggcagtg ggaaggggag aggtctgcat gtgcatgtac 268860 tggacagcat attccatgtg ggtcatggag tgatgactgt gggcctcttt cgggcattgt 268920 agcaggcccc catttcattt catgatgacc tcggggtgct gggacaggaa tgtgattgcg 268980 ggtccacgtg cttctgcaac tcctcagact gacttggttt ggaaggtctg tgttcaggac 269040 cctctgtgag atgcttgtct ccattaggca tttgagctta tatcggccca gggtttctac 269100 ctatcgtagg ttgtgcatac tttgcctctg aaccactcag gcacctcgat gcagtcaacg 269160 tgcccgatta taagagtgtg acttcccata tcctggtgat ctctactcgg aaacatggtc 269220 caggaaggtc tctgtgctta aataccttag tagctcgtga tgttaggtta ttttctaatt 269280 cctcctaatt cttcccagga gtcttctttg tgaaatagtc atcttgttgt aggacagggc 269340 tggtatccac aggcagtgat gcataggttt tgcactgcgc ggccatgttc aaaggcaagt 269400 gccttaaaat gtatggtgtt ctcagccaca gtgccttaga agccatgtgg gattcagtgt 269460 gtctggtggt cctctgagct gcacctgtga ggaagacgct gaggtagagg ttaagttgtt 269520 attgaacgtt tttctcaatc tgaaaagtgt tcaagcagcc cagggtgaaa agtcttcaag 269580 actgaaggaa aattgccttt tgtactggaa gagtttttcc ccaaaactct cctcatttaa 269640 atagccctgt ggcttgtgtc ttctctgatg accaagagga gggcttttga gtcagtgatg 269700 gcaaatgagt ggttttgaga gagttcttac acttagggct ctgtagcttg atggtgcctt 269760 caaaattaac acgtgcctgc tatcttcatt cctgggtaga cccatacacc catcccaaaa 269820 ggggagtagc ctgtgggaag cacatatggg atataccaca gtgagtcgag tggaatggcc 269880 cttttgacat gtgtacctgc ctcccgttct taagcacacc cgtttttcct ctgcacttcc 269940 caggtgttgt ggccatggaa gtaaggccag tggctacgag ggacagtctt catcttggga 270000 gatccctaga gagggcaggg agccccttga catgtggaat gtgatctctg ttgggtgctg 270060 gtggatccca caggttggta aatgtccatt ttccaaaagc ccctgatgtt ccttctttgc 270120 agggataaag actgtgcatg gatcgatgat gacctcaata catgcattcc ttggaaagct 270180 gaacaaaatg agtgaaaact ctataccgtc gtcctcgtca aactgaggtc cagcacgtgg 270240 ctccaactgg agctggagag agagagacaa cttccattgg ttgatgtggg ttgcactaag 270300 ccatccatcc aggcttagga tggggtccac tttggatcaa agggagtcac agggcagtag 270360 gtgctcctgt gcagaggaga ttccttgtgt gaaggacttc tctttgtgag gctgggtagc 270420 acgcacaatg tctgcaggac tgggtgaatg tgcaggtggc acagaagagt tagccggtaa 270480 cccgcctctg tgtggccagg tttgtccttg agtgctggct ctgggttccc ttgttcccca 270540 gaggtagata gctccttgtg gttgggaaga gagcccaagg ccacatcttt gttgttcttt 270600 ggctcatttt ttttcatggc tgaggacttt ttagtgccca tggtgttttc gtagcagcag 270660 tggaagtcag ttgtgaggag gttggtgatg cttattttct ttctggagag taccctgtag 270720 atcggctcca tttatgattt gtgtgtctcc agggagaaac tgaaatccca tggctggtga 270780 tggatactcc aggtgggaat gagaaagcgc catacatgtg ttgacttggt accctaagat 270840 ggggatggtc cgccacattt gcgcgtctgt tttgcatggt gtgtactgca catcacaaat 270900 gccatgttgg ccttagggtg ctgggaatgg aatatgatct gatgtctaca tgggagggcc 270960 tttcagcaga ttgcttttgt ttcctgacag tctttgctcc atccccagtc acacgtgttt 271020 ttctccaggg aacattttat tggagtatat caggtcgata tcagaaaaaa aaatgttgtg 271080 gttatcccaa cattaagtgt ggtgatgtaa cagcagtgtg gatggtagct caagtgaaca 271140 gtggcaaaac caaaatatat tggtttacgt aagtgaccct attctctcct atgtttgaag 271200 tctggtatgc atctctttct gcaataatct cagtgatctg gaaactttca ggaggtcttt 271260 tttagatatt ttatgtcctt gtggttgtac tcatactccc tgcagtgcta agtctgagtc 271320 attctgctat cctagtgcta ctggaatttc tattgttttg ggggcactgt ctggtcattg 271380 tggatacctc tcttggggcc ctttaataag aagtatgtta gaggtcggtt ttggggcagt 271440 gttgacctcc tgcctaaggt caaaggcagt tttcttccta aatcttattg caggattcac 271500 tgcctggggg ttgtgtgaca gggagagcac aaaattaggg tatcccatgt ggacttgtgt 271560 ccagtatcaa ggcagtgttg gataattttc tatatccaca aggctcccac tggactcttt 271620 atgtccagca gacattcaca ggccaacttt tctcttacac agggggcctc attcctgcca 271680 tgtgtagctt ccatggaacc atccttcagg ttttaagtgc aaggatttct ctcaagagtt 271740 taatttgttt ctttaagaca ccgttttctt ttctataaat tctgctttct gtggtttgta 271800 gcacagatga aattgccagg tcatattcta catttctgcc caatcttgga ttagtgagcc 271860 tttgaaatat gttccttgat cactggcaat ggttcttgga ataccagaac ttagttacaa 271920 gcattgcaga cctacagagg tttgttgtta tttttaactg catgaagcag tgggtttgtt 271980 tgtatcttgt cactcacggc tgtcagcaaa acttaggtgt tgctaaacca gaccacaccc 272040 atgaattata gtgcctctgg ttccttctgt agtagcctgt gggaagtaga tacaggatgc 272100 accacaaggg aatgaatggc atggcccttg agacctgtgt acctgcttgc ctttctcaag 272160 cacacctgtt ttgcctctaa ttcctaggtg gtctggcatg gaagaaggcc agaggctgcg 272220 atggatcatc tttgtcttgg gagattcctg gagatggtgg ggagcccctg ggcacgtgca 272280 gcatatgtgg cgtgggcttc ttcaggtgct ggtggatccc tcaggatggt aaatgtccat 272340 tttccaaaat cttctgatat tccatctttg taggtacaaa gactgtgcat ggatcgatga 272400 tgacttttat acatgcattc cttggaaagc tgaacaaaat gagtgaaaac tctataccgt 272460 catcttcgtt gaactgaggt ccagcacatt gctccaacag tgggtagata gagagggaaa 272520 acttccattt gttgacgcag gttccattga ggggtttgtc caggcttagg atggggtccc 272580 ctttgggcaa agggagtcac aggggagtgc ggcctcctgt gcacaggaga ttccttgtgt 272640 gaaggattta cctctgtgag agcagggtag cacacataac tatgcaggag caggtgaatg 272700 tgcaggtggc acaggaagag ttagatggca gcctgtctct gcacagcgag gtttgacttg 272760 tcctagctct gcattccctc atcccttaga ggaagttggt ttcttcagaa gacttaaatt 272820 tgtggaattc agtagaatat tatccacata atgttcccag tgaatgctag gcatatcacc 272880 caagatggcc aggcctctgg ccataaacca tagtaaatag tagggtgtgc atatatccat 272940 tagggagaac ctgaaaggtc cttttttggc cctccaaggt gaatgcctgc aaaagcaagc 273000 gaagcacgct atctgcctgc atgagcccca tgtacctggc gtggcctgtg ctcctcaccg 273060 tgtgtcccac ttctgctgcc ccttcgcctt gccaggtgga gtctgactga ttttttgcca 273120 ctgctgccac cacaggccac ctggagcccc agccagtttg aggaaagtgg ctctgcttga 273180 ttttcctttt ttcttttttt ttcctctttt tttctccatt tctgacttca gcaggtggga 273240 cttggagctt ctgcttctgc agccacagaa gactccccag tttggagggc tgtggttgtg 273300 ggctccctaa gcatctctct gcagagcctc tttgttttcc attttaccca ccatgtcaat 273360 aatttaacac agtggcggag gagttcatgt ctcttcctat ttgtcattac tcttctaact 273420 ttcacagctg tactcggcta ctggtcagaa taagagaaaa agcagtggaa ccaggaggat 273480 cctacaagaa atattccatt tcacttttgt ttgtgcatat accttttctg tttaaatgtg 273540 gacttcgatt tgatatgctt ccagtgcaga cacagatccc atatgtaaga gagtatggag 273600 ttgcatagaa agaagacttg tcattttcct gtactgttgg tgttctaatc tgtcttcgtg 273660 gtttttgcct cttctggctt tagaagatac accaacatgg ttttgcaaca tagcctcttc 273720 ttattttagt aagggaccaa atgtgcatgt cagtaacagg tgttaccttg aattgggatc 273780 agtgcttgtg tgactatatt cagtgatgtc attttctgtc acactcaagt cacaaaatat 273840 ttaaccactt atttttttat ctctggagga ataatccaaa agattgtact ggtaaagcca 273900 gaacaatttc caattatgct aattatttgt ataatactta gttggcttta tctgtggttt 273960 gttggcttat tttcctgtag cttttcaagg tttttctatg agttctgtta aagagtctga 274020 aaatggagcg tagaagacat gcttcgattt ccaggatggt tgtgttttcc agagaggcgg 274080 aggtaaacca ctggcgcagc cctgcctccc acagataatt ccgggtgcag tgtttcatat 274140 ctagacttgg acttctatcc taccatactt ctttgtgtgc aggtattttt ggggataaaa 274200 tccttgtttt cagctgtata gatgtcttgc acatactctt ttgatggttt gatttatcca 274260 ttgtgttcag cacgtttcag tgagcaagat atgggattta atttccaata taaaatccat 274320 gactgctggc cgggcgcagt ggcttatgcc tgtaatccca gcactttggg aggccatggt 274380 gggcagatca cgaggtcagg agttcaagat catcctggcc aacatggcaa aaccccatct 274440 ctactaaaaa tacaaaaatt acccatgcgt ggtgttgtgt gcctatagtc ccagttactc 274500 aggaggctga ggcaagagaa tcccctgatc ctgggaggtg gaggttgcag tgagctaaga 274560 tcatgtcact gtattccagc ctgggcgata gagactctgg ctcaaaaaaa aaaaaaaaaa 274620 gaatgttata attattttca gcctcatgtc tccgtgtcac acacaggtcc atgaagctgt 274680 gttctttttt tttttttttt tttttttttc agagtatttt ctttcttgtc cagattagct 274740 aaattggatt gttctatgct aaattcactt aatcactact ctattatttt tgaatttttt 274800 agttctgttt ttttcacttg gttctttttt taaaaaaact tctactacct ttctgagact 274860 tctacttttt tacttttttc aagaagcttt ataattactt gctaaagcat ttttaccatg 274920 actgttttta acttcttcag ataaccacaa catttggtta atcttgaggt tggcttggtt 274980 aactgtcttt tctcatcctg cttatgattt tccttctaat tgtgattttt ccggttcttg 275040 atagatgggt gatgttttag tttatcctgc attttttttt cctttttaag ttagaggaat 275100 ctgaatctat tcaaatgttt tattttagca ggcatgtgcc ctgtttaggt ttaatttgaa 275160 tgtcctgtcc tacttttgta ggccatgttt tcgcaggcag tcttgctatc agagctgagg 275220 ggatgctgtt ttgatcactt agtttatctg atgttgctgg gcctccaact ggtgctgact 275280 ggtacttcct gagatggcga aggtttttct gtactctgag atgccgtgta tctctatgta 275340 aggggaggag actctggacc acaggaatga agagaacatc ttaggtcagg cagctcaatc 275400 atatgcgata acctgggtca accagccagt agcctcatga agtatgggag ggaattctcc 275460 agtgtcagca ttcaaagaca tcatgagttt ttacttctca ttttctttta agtgaaataa 275520 tcgcatggaa attaaagaat aaatatatga aatatatgaa acttatatga aatataagaa 275580 tgtgagaagg cctacagcgt ggggatcccc aggctatttg aacaatgaat gtctgtgtta 275640 cacatctttg ctcacttttt ctctattttt gtagttcatt gtggaaccag cacagatttt 275700 catacgaaag ttatttcttt ttaacctcaa aaagtgacag aatggagtgt atcatgaaaa 275760 agtctgacat caaaacctca aaatgtgata ttggtaagca ttttgtcctg agaataccag 275820 catttcctct taggggatca tgacactgca gtgaccatgt gaccctggct gtgctagtca 275880 gcctgggctg ttcattgact gtgatgctgg tctccatgtg attgactagt gtgggtcagt 275940 gcctccaaag gtgacagctg tgtgctcagt gtctgccaca tatctcaggc tcaaggtccc 276000 ttttataaat gtgcctggat cgatgatgac tttaaaatgg atctcatcgg aatctgaaca 276060 aaatgagtga ccaaatcact tctgtgccac ttctgtgagc tgaggtccag cacaggggcc 276120 atgccagaca aacacatgga gggtgttttg tttggtcagc actggtacta tgaaacggcc 276180 tgtggaatta gacaactaac cagctcacat acagtacagg aaattactgg acagttaacc 276240 taccaatata tggttggggg taagacggag acttttcaaa tgcttggctg gtagcatctg 276300 tacactacag tgaccagaca ctgggagcca gcacaggagt tataggattt acaggaaatt 276360 attgtgtgaa cccacaagcc attcagacat ttgtgtgagc gcccagaata ttctggttga 276420 tggtttgttg cttgatggca aagagatgtc agcattcaaa gacatcatga gtttttactt 276480 ctccttttct tttaagtgaa ataattgcat ggaaattaaa gaataaatat cttatatgaa 276540 atatatgaaa catatgaaat ataagatatt tatttatatc atataagata taaatatctc 276600 atatgaaatc ttgtagtata ttttcatttg attgccaacc cagtcactag gactgaaaca 276660 gttgtttatt ttttgttttc ccatcaacca agcaagctat ttaatacatg tttcagtgct 276720 ggtttcaact acatgttgca gcaaacattt ttagaagtga tatttcaaat tcttggattt 276780 tcacatggat ttcattgtct actttcatat gtcctccatg tgtgaccact gtattaatta 276840 aaagttgtaa taaatgattt tgaaaggtat gtgctggagg aacttcggga caaatgtttt 276900 agaaaacatt atttccataa aatttggatc aaagatgtga gcataattgt tcttgttata 276960 cagatggtcc aatgagtgtc taatgtgaat tcttataact gtttataaca aagtagtcca 277020 tgaagcaaat tttgtttcac aactttccta atttcccctg tactctgtag attgggtgag 277080 atagaattcc atggaatttc attgccaaac cagtgaagtg ctaattttga catttgtacc 277140 agctaacgta gctgtgaaga aacacaccaa tacacttcta aggtaacatt caatttttag 277200 tgaatttatt tttgtgagtt atttttattc ttttaagtaa tcaagaattt atgttcacaa 277260 ggaattggtt aatactaaca gtttcagaca ttaatgttct gatgagctga ggcatcaatc 277320 tccttttgat aaaggttttg ttcttttctc tactttgaat aacatatgaa atgtccaaca 277380 gcagttctaa gttagtgtat attccatata tgttaatagt gaaacatcct gtcttatgca 277440 aggctaaaaa ttgtccgtgt atacttctca gatttgtata catactctct tcctacagga 277500 cagcatagac caagatctag gtttcatatg gatgaattta ttcttccctt tgaggcaaga 277560 caagaaggaa agaaagtatt gggaataatg ctgccctccc atcctcaagg gccagtggga 277620 actctaatat tggtaagcct tttgtcctga aaataccagc atttcctctt agggaatcat 277680 aacactctgc taaccgtgag actctggcta tgctagtccg ccatgggctg gtcattgact 277740 gtgatcctgg tctccatgat tgaatagtgt gggtcagtgt gtcccagagt gacagatgtg 277800 ctcagtgtct gccacatatc tcagactcaa ggtccctttt ataaatgtgc ctggatcgat 277860 gatgactata aaaaaaatgg atctcatcgg aatctgaaca aaatgagtga ccaaatcatt 277920 tctgtgccac ttctgtgagc tgaggtccag cactgggacc atgccaggca aacatgagga 277980 gggagtttac agggactagg gtattggaaa actaacctac ccatatatat tagagcaaat 278040 gaattgttct cagttctgta aatatccagc tgtggtttga catagcaact ctctttgtat 278100 ttgcttggca gcatttatag aaacagctgg tagaccctgg ggaaccaggg catagtgaga 278160 ttcatgggac gttatttcac ctactcttga gccattcaca catttgagct cgcagaatta 278220 tctggtcaat gagcagtctc ttgagggtaa tgagatggtc aacatccaaa tccaaagata 278280 ctaatgagat tttacttttt tttttgagat ggagtctcat tctgttgccc aggctggagt 278340 gcagtggcat aatctcggct cactgcaacc tccacctcct gggttcaaga gattctcccg 278400 ccccagcatc ctgagtagct gggattacag gcgcccgcca ccacccctgg ctaatttttg 278460 tgtttgtagt agagatggag tttcaccata ttggccaagc tggtctcgaa ctcccaacct 278520 caggtgatcc agccactgca gcctctcaaa gtgttgggat tacaggcatg agccgccgtg 278580 cccggcctta ctttttattt tcaattaagt gaaacaatta catggaaatt gaaaaaaaaa 278640 aaaggtactc taagtagact actctagtgt attttaattt tcttgccaat tcagccacta 278700 ggattgtgtc acttgttttt ttgattttag tttttcgtat caaaaagcaa accactgttt 278760 atatttgagt gctggtttca actgtatgct gcctcaaata aacttagatt atattacaaa 278820 ttctttttta catagatttc attggctata ttcatatatc ctcaaaggtt tccattgtgt 278880 ttgaagaggt atcctaattg taataaatgc ttttgattgg ggatgccagg gaagctttga 278940 gactaatgtc tcagattttt tttaaaaaag tttatattct atagtgatca aagatgtaag 279000 aataattttt cttgtcattc attggatagt ccagtgagtg tctactgtga attcttatat 279060 tcacttgtaa ctaaacattc catttggcaa atttcgtttc ataacttccc taatttcctc 279120 tacactttgt agattgggtg agatacaatt ccatggaatt ttaccactga accagtggag 279180 ggctaatttt gtcatttgta ccagttaact aacttgggag gaaacagaac aacacactcc 279240 tgaggtagta tccaattttt agtaaattta tttttattat ttttcaaact gtcagtgatt 279300 tggtttggtg aacaataggt taatacagac aatgttagga attattaatc tgatgcgcta 279360 tctgaagcat cagtttcctt tatttttaag atttttttct tctctgtagt ttggataata 279420 tttaaaacat ttccaagagt tataaattag tatattttct atgctgatta ataatgaaac 279480 cttttgtctt atacagattt ttaaaaaatg gacgtgtgcg tgcatgtgta tatatataaa 279540 tatatatata tataaaatct cttctcacaa gatgatgcag actaaaactg cattttacat 279600 tttatatggc taagtttatt gtttccttgt gttgtaatat gatggaaagt aatgggaata 279660 attctgcttc ctgtccttag ggaccagtag gaattttccc atgataagca ttttgtcctt 279720 aaaatactga catcctgtta agagatcatg acactccaat gaccatgaga ccctggctat 279780 gctagtcagc cagggggctg accattgaca gtgatgctgg tctccatgat taaatagtgt 279840 gggtcagcat gtcccagggt gacagaaagc tgtgtgatca gtgtctgtca catatctcag 279900 actcagggtt cctttttaaa atgtgcctgg atcgatgatg acttaaagat ttatctaatt 279960 taaatctgaa caaaatgagt gaccaaaaca cttctgtacc acttctgtga gctgaggtcc 280020 agcacagaga ccactccagt caaacatgtg ttgcctggag ttgcaactag ttggtcagtt 280080 agaagcaacc acagggactg gggtatttga aaaccacttg agtgcattta ttagaggaaa 280140 cgaattttac atttgtgtat aaaaattcaa ttgtagggta aaatggaaac tctgagagtt 280200 tggttggcgg catctatata ccatagaaac agagcctggg aagcagaaca gtgagaccca 280260 agagaaatgt tcctgcctat acttggtctg ttctcacatt tgcctgagct actgattgat 280320 cttttgaggg tgatgagatg gtcaaaatcc aaggatatga tgagttttta cttctcattt 280380 tctttttttt tttattatac tttaagtttt ggggtacata tgcagaacgt gcaggtttgt 280440 tacattggta tacacgtgcc atggtggttt gctgcaccca tcaacccatc atctacatta 280500 ggtatttctc ctaatgctat ccctccccta gcccctgacc ccccaacagg ccctggtgtg 280560 tgatgttccc tccctgtgtc catgtgttct cattgttcac ctcccactta tgagtgagaa 280620 catgtggtgt ttggttttct gttcttgtgt tagtttgctg aaaatgatgg tttccagttt 280680 cgttcatgtc cctgcaaagg acatgaactc atgctttttt atggctgcat agtattccat 280740 ggtgtacatg tgccacattt tctttatcca gtctatcatt gatggacatt tgggttggtt 280800 ccaagtcttt gctattgtga atagtgccgt aataaacata tgtgtgcatg tgtctttata 280860 gtagcatgat ttataatcct ttagatatat acccagtaat gggattgctg aatcaaatgg 280920 tatttccagt tctagatcct agaggaattg ccacactgtc ttccacaacg gttgaactaa 280980 tttacactcc caccaacagt gtaaaagtgt tcctatttct ccacatcctc tccagcattt 281040 gttgtttcct gacttttttt aatgatcgcc attctaactg gcatgagatg gtatctcatt 281100 gtggttttga tacacatttc tgtaatgacc agtgatgatg agcctttttt catgtttgtt 281160 ggctgcataa atgtcttctt ttgttttact tctcattttc ttaaagtgaa acaatttcat 281220 gtggtatctt ccaagtatat tttaatcagt tgccaaccca gctgctaaga ttgaactgtt 281280 tcttttgttc ttctcttgtt tttttctatt aatttagcaa acaattttat atatagtttg 281340 ctatccttct ccatggggcc tgcatcttca gattcaacta gccatggatt gaaaatactt 281400 gacaaaaaat tgtatggttt catctgtact gaacatgtac agtctttttc tctctttttc 281460 tctttctttc tttttttttt ttttgagaca gagtttcact ctgtcaccca ggctggagtg 281520 cagtggcacg atctcagctc actacaacct ctgtcccccg ggttcaagtg attctcctac 281580 ctcagcctcc tgaatagcta ggattacagg cgcccaccac tgtgccaggc taatttttgt 281640 gtttttagta gagatggggt ttcaccatgt tggccgggct ggtctcgaac tcctgacctt 281700 aagtgatctg cctgcatcag cctcccaaag tgctgggatt acaagcatga gccaccatgc 281760 ccagccaagt acagactttt tctttggtta ttattcccta aaacagtaca gtataacaac 281820 tatttacgca gcatttacat tgtattcagc atcatgagta atctagaaat gatttcctgc 281880 atataggagg atgtacatag gttctatgcc aatagtgcac agtgctcgct gtgtttaaag 281940 aaatatccta ggtatagaat aaataatttt gaagtcagtg tgttgagaaa acactgacat 282000 ggatagaaaa tattctgtct agaatagaaa aaacaataga atagaaaaag ttctatctgt 282060 atcagtctga tcaaagatgt gagcataatt attcttgtca tacatatagt ctaatgaatg 282120 tctaaagtga attcttataa ctgcttgtaa caaaatattt catttggcaa atgttatttc 282180 acaactttcc taattgccca tgtactttgt agattggttt tcacagaatt ccatggactt 282240 taactgctga accaatgatg cactgatttt gtcacttgta ccagctaacg catctgggag 282300 gcaacaaaac aatactctcc tgaggtaaca tcgaattttt agtaaattca tttttgtgtg 282360 ttgtttttat tattttttta agtaattgag aatttcatta ggtgtgcaag gagtcactta 282420 atacaaatag tattaggcat tcaatactct catgagatat ctgagccttc agtttctttt 282480 attttaacat tttacatttt tctcaacttt aacatcagaa acatcctata agtgtaataa 282540 aattcttata ctttacatat agttacatag taaatcctcc tgtcttattt aagtttgaaa 282600 aatgaacatg tatacttctc attcccatgt atataatctc ttcccacaga atgaggtgga 282660 ccaagaaact gggcttcata cggatgaatt tatttttttc cctgtgtgga gacataaagg 282720 aaaagtatag tgaataattc cgcctcccac ccacaagtcc ccatgggaat tctcacatgt 282780 taaaaagcat tttgtcctga aaataacaac aatttttctt agggaatcag gacactccaa 282840 tgacagtgag actctggcta tgccaggcag ccatgggctg gtcattgtgc tgctggtctc 282900 catgattgaa tagtgtgggt cattggtgac agatagctat gtgctcagtg tctgccacat 282960 atctcaggtt caaagtccct tttataaatg tgcctggatg gatgacgact taaaaatgaa 283020 tctcgttgga atctgagcaa aacgagtgag caaaccactt ctgtgcagtt ctgtgaactg 283080 aggtcaagca cagggaccat gccaggcaaa cacgtgcaga gagttcagtt tggtcagcaa 283140 ctggtaccaa aatggcctgt ggtattggaa aacaaaccca ctcacatagc ttacagcaca 283200 tgaattgtac agaggtctgt atgtgtttgt atatatttat atatgtttgt gtacatatat 283260 ctttggggat tatatggcat ttctttcagt gtttggctgg cagtgtccat actctcatag 283320 taaacagaat tacacaagag tagagggaac agtaggaaat ggttttgcct accctagagt 283380 cttttataca tgtttttagg tgctataatc ttgtgtgtga ggtcagtctc tcaggttcat 283440 tagatggaca gtgtaaaagg tattatgagg ttttacatat tatttatcta ttaagtaaaa 283500 gaaatatatg gaaattgaag agtagctttt atctattaaa gaaaagaatg tatggaaatt 283560 gaagggtact ttctatttgt ggaaagtctt aacattttaa tttccttatt gatcttgtca 283620 cagaagttgg aatttaagtt ttgcctgtca ctcaaagaga agctttttag acatttgatt 283680 aagggattct agtagatgct atagtaaaca tttctaattg taaaatgatt aaatttgcaa 283740 ttcatagagt tttatgtgga tttcattgcc tgatattcat tatttttatt agtgggtttc 283800 atagatgttt aaagggagat cctagtttta ttgtgtgata ctaagggagg ccttttggtc 283860 ttagaaaact gactttcagt actacccatt tccagggagt gagcataatt tttattctca 283920 taccacatgg gcaagtgaat atctatggtt tatttcttat aactcgtcat tagtaattat 283980 gaaagtaaga aagttgacaa atgaaactct tttaattatg agggtttcat ttgtcgactt 284040 cctacttcct cagtgtgctt tgtgtattgg aggtaatact ggaattgcat ggaattccta 284100 ctgctgctcc agtaacctgc tgattttgtc acgtgtacca gattcgttgt ctggcaatga 284160 gaacaataca cttcagaggt aatattgcaa tttttagtaa gtgcattttt cctgggttcg 284220 ttctattatt ttattttagc aagtaagatt ataattggtt tttcaagcag tctgttaatc 284280 caaatggtgt gaggccctaa taatctggtt agtcatctga agtttctgtg ttctttgtac 284340 agtattttta tacttcctct gttttcaaat aacattagga taccctacta gcaaaataat 284400 ttagtatatt ttatatactt gtgcatagta agcctgttgt atatgtacac tatttgcatg 284460 gttggcaaat tacatttgca ctttttattt ttctataatt ttttcctatt ttcaaaggtt 284520 aatgtggacc aaaaactaga tttcatataa aagagtttat tccttctact tgaggtgtga 284580 catgaaggaa agtaatggaa ataattctgc cctcccattc tcaagggcca gggggaattc 284640 aaatattggt aagcattttg tcttgaaagc accaacattc ttcttagggg gtcatgacac 284700 tccaatgaca atgagaccct ggctgtgctt gtcagtcatg agactggtca ctggctgtga 284760 tgctggtctt tgtaattgaa tactgtgggt tggcaagtcc ccaggtgaca gaaagatcag 284820 tgttcagtgt ctgccacata tctcaggctt aaggtccctt ttataagtgt gcctggatcg 284880 atgatgactt aaaaaaatgg aaaccttgga aatctgaaca aaatgagtga ccaagacact 284940 tctgtgagct gaggtccagc acagggacca taccaggcaa acccgtggag ggcgttcagt 285000 ttggtcagga actggtacca aaacgaaccc acttgcatat gttagagcag atgaattgta 285060 cagaggccta tatatcttcg ggaattacat gacaatgatt taagtgcatg gctgacagcc 285120 ttcaaacacc tagtaatcag gctttggggt accagcgtca gaggagtgaa cactgtagaa 285180 atggctgtgc cagcactcga gtcattcaca ctattttcgt agacgccaca acattcttag 285240 tgagtatcag catgtatagg tatattatgt agtcaattag aaagaaatta tcagtctttg 285300 cttgctattt attctttcac taaaagaaat atgtgaaaat tgaagagtgg gttgtattca 285360 tgggattatc ttattacatg ctggaatttg cttcctaact cagtctcaag gattagaaca 285420 gcatttgttt ttctttttcc tgtcactcag ggagcaattt tctaagcatt agatgataga 285480 ttaaattaga tgcttcatta aacattttaa tgtgaaataa tgaaatttct aattctaggg 285540 attttagatg gatattgttg gctaatagga atattccttc attgagtctt tgtatatttt 285600 aagagagatt ctaattttag taatactcgg ggcctttggc cttcgagacc aaaatcttgg 285660 aaacattgat tttctgtact taccctgttc caagcaacaa gcagattttt tagttatgtg 285720 gatagtcaag tgactatggc taattaatta caaactgttg tcaggaatca ttcagttggg 285780 aaggttttgt ttcaaaactc ctgtaatgtc ccctgtgcct tgcagaacgg aagtgatttt 285840 ggaattgcat ggaattctca ctgccatccc aaagaaatgc tgatcttgtc actcttacct 285900 gtttcattcc ctgggggcag aacaaaagga cgcactccaa aggtaacatc caagtttgaa 285960 taaatttact ttttatggct tattttgtaa ttttttctgt agtcaagtag ataatcagtt 286020 ttgtgaatga tctgttaata acagtatgag acattaatta tctggtgaat catccaaggc 286080 tttcattatc ctttatttcc aatttttttt gcgttctcct tttcagtaat atcaaaaaca 286140 tcctagtaga gttatgttag tatatttgat attaatatac ataacaaacg ctcccttctt 286200 gtgcatgttt gacaaatgga catatatact taccatcttc ccatatttgt actgttttca 286260 cagatcggca tgaaccaaga actgggtttc atataaaata ttttattctg tcctcttgag 286320 atgtgacatg agaaaagtat tgagaatact tctatcacct catcttcaag aatccgtagg 286380 aattctccca tggtaagcat tttgtcctga aaatactggc attcctctta ggagatcgtg 286440 acactccaat gaccatgaga ccctggccat gctagtcagc cattggccag tcattgactg 286500 tgatgccagt ctccataatt gaatgaatag tgtgggtcag tgtaccccaa gctgatggaa 286560 agctgtgtgc tcagtgtctg tcacatatcc caggcttaag gtacctttta taaatgtacc 286620 tggattgacg atgactttaa aaaaaaaaaa tctcattgaa atctgaaaaa aatgagtgac 286680 caaaccactt ctgtgagctg aggtccagca cacatgatag gcaaacgtgg agggatgtgg 286740 atggtcagtg cccacaggga ctggggtatt tgaaagctaa tctgcctgcg tatgttagag 286800 gaaatgaatt ggacagtcat ctataaatat cgtatttttt aataaaatgg ctattccttt 286860 ggtgcttggc tggtagcatc catccactgg tagtaaatag accctggaaa accagcacat 286920 atgtagtgag accccatgag acatgattgt gcctaccttt gagccatcca taagttatct 286980 gggacatgac agtcttttga gtgagagcag tttactaagg tcatttagat catcagttcc 287040 aaagatggtg tggatcttat cgattatttt tttaggcaga ggtaatatct ggaaaattaa 287100 gagtgatttc taaccatgag aatattttag tttgtttaaa tttgcttgct aacccagtac 287160 caagaattca gacctttttt ctgtctgtat aaagcaatat tctagacatt tgagtgattc 287220 aagtagatgt tgtgagatga ttacatttcc agtccttgga atgttatgtg gattttattg 287280 gctaatcttc atatttcatc agtggatttt cctatgcatg ttaagggaga tccttgttaa 287340 ttgatgtcta ggtggacttt acggttaacc tgaacaggtc ttggaaaaag gactttaaac 287400 attctcctgt tctgtggaat aagtatactt ttttctggac atacaccttg tcagtgagta 287460 tgtatcataa ttcctcataa cttcttatca ggaaacattc gatgtagaag atttctttct 287520 caacttctct aattgcccct gtggtttgca ggttccatgt gatactagag ttgcatagat 287580 ttttaacctt tacgccaatg aagatctgag gcaaacattg cccctttttt agaagtttgc 287640 atttgtcact gataactgta ataattgatc ttgttgaaaa gcctgggaaa tgaagatctg 287700 atatgtcact tttaccggct tcctcaactg aaaaagaata caatgaaaca cgctgaggta 287760 acatctaatt tttgatatct tttttcctgg gttattactg ttttaagtat ttaggaattt 287820 aatgggtgct atatggagtc agttaattca gatactataa gaccttaatc tggtgagtca 287880 tctgaggctt ctgtttgttc ttttccagaa tttttgtgct ttctcagtct tgctgatgat 287940 ctttctatgg gcctgaagcg tggagagtgc cagagaggct gatcctcagc agtgtggcag 288000 aggaaagttg ggtgcgacta aggggtatgc ggtgcccaca tgccactggg tcctcagcag 288060 taccacctgg tgagcgtcac tcttgagagc tgagagtagg tgggaagcag ctcatggtga 288120 gagggttcag aggccgcctt tccctctctg cgcactgccc agttcttcta gtcacatgtc 288180 ccgggacagt accatacctg tgtgtgtcct gcctgcattg ctgtgaccac ttttagtgga 288240 atcaggtgca gtgcagctct gcagcttctg caaattgcca cgctcccact ctcaagcagg 288300 ttgagtgcta cgagtgattt ttagaccatt tgtttattcc cttatcatgg ctttttgtga 288360 cttcttcctc cccagtccgt tgggtcacct ttaaaggtaa agtaatcctg aggtggttga 288420 atttacggaa atgctatgca ttattgtgaa tgggatgttc accgggccaa catcttcttg 288480 gaactttgag caaactgata gtctggttgc acatttgatt tgtctggcag taaatgttgg 288540 acagtatttg gactgatgga agctagagac aaacacattg actattgttg aataacactg 288600 gaaacatctt aggagagcag tacattagct aatttaatag gtacataaac tgaatcccac 288660 tgtcttgtgc ttgacggacc agcagacaca tatgcttgta tcgttctcat gtttctacat 288720 gtttacccta ttcccacagg tcaacaaaga caaggcacct agccccacat gaaactttat 288780 tcctttccct tttgagatgt gacatgaaag aaaataacag aaatgatttt tccatcccat 288840 cctcagggac cagtgggaat gaattttacc atcccaccct caagggccag gtcaggtcgc 288900 taagcatttt gtcactaaaa tattgccctt ttttagggat tatgtaatac tctataaggc 288960 actgtctgtg ctgggcagca tggagcctgg gtcattgctg tgttgggggc ttggtctcca 289020 tgacttaata gggtgtatca gtgtgtccca gagaagtgta ctccagagtg ctcattttct 289080 ttcatgtttc tgaagcaaac agtgccccct tttttagaag tttgcatgtg tcactgataa 289140 ctttaataat tgatcttgtt gaaaaacctg ggaaaacagt gagttaaata ataacttctc 289200 tgaacatgag gtccagccca attacctgcc ctaagcaaac tatatggaag gagagttcag 289260 tttgttcagc tatgtggtcc cagcaaggac tgtggtactg gaaaactaac cagcttacat 289320 gcactagaga agtagaattg gacagtgatc tgtaggtacc cagtttggag atgaaattgc 289380 aactctgagt tcttgattgg caacataaat acgttgatag taaacagacc ctggggaatc 289440 agcacttgag ttgtgaaaag cgggaaatag ctatgcctac actagagcca ttcacacttt 289500 tgctggagct gcaataatct tctaagtcat gcttgctctc gtgagggcaa tgagatggtc 289560 acaatccaag gagagttggg gttttcactt ttcatttctc tattaagtga aaaaagtata 289620 tgaaaattga aaaatagata ttacttatgt aatcttcaca gtataatttg cttgccaagc 289680 agtcactggg atttaatcag tttctttgtc tttcgttttt ctcataagct gagagagtaa 289740 ttttgtgtgc acagaagtac tgtcttcagc tacatgctgc attaaacatt cctagatgtg 289800 aaatgattaa atttccaagt ttttaaaatg tggatttttc tggccacttt tatatctctt 289860 caatgggttt ctaatggatt taaggagaga gcctagtcat gatgaatggt gttgtgttgg 289920 gtatgctgag gaaactttga gaccaatgtt tcagaaaaaa ttatttctat actgtcatgt 289980 ttcaagtacc gagtattgtt cttgtcatac agatggtcca gtgaacatct ctggtgaatt 290040 ccttacaacc aacctcttgt tactaaatat tccattagga atgttttgtt tctcaactcc 290100 ctgatttccc ctttatagat tggaagtgat attggtggaa gacaacattt tgccgcttgg 290160 aattctcacc tccacaccaa agaagtactg tttttgtcat ttgcaccagc ttctttctcc 290220 aggaaagatc aaaacgatgc actgcaaggt taacatccaa tttttaatac atgtaattcc 290280 ctggattatt tttgttgtgt tattaaataa cttagaattt tttttacaaa gtctgttgaa 290340 ccaaacactg taaggcatta ataacctggt gagttatttg aggccttttt tcctctccta 290400 gaatttttgc acaatttata ttttgaataa tatcagagac atcctagtag agtaatgaat 290460 tagtacattt tatatgcaga tacatagtga agcctccttt cttatgcata tttgacaaat 290520 ggacatgtat atttctcatc ttcccatatt tttactccat ttccacaggt catgtagacc 290580 aaaatgtgaa tgtcatatga aagagtttaa acattgccct tgaaatatga cagaaagtat 290640 cagaaataat tataccattc catgctcaca ggccagtggg aattctcaca gtaagcattt 290700 tgtccagaga atattcttct tagggaacta taacattcca atgataatgg tagtcagcca 290760 tgtggctgga tcatcgttcc tgtatcctgg tctctatgac ttagtgtggt gatggtgtca 290820 ttgtgtccaa gtgtgacaga attgttagtg tgtagtgtct gtctcctatc tcaggctcac 290880 agtccctttt ataaacatgc ctggattgat gatggcttca gtatcttttg gaaatctgga 290940 ctgagcaata gaattgcttc tctcaaattg atttcaagtc atataaaagg ccatgttaca 291000 catatattgt taatctgagg gaggctgtga tcatttaagt tgtattttat aaacactagg 291060 accaccagta agaaaacaat tcaaaaaata ttaaaagaac aaccaaagaa ttaaaataga 291120 ataaccgaaa agatctgttt aacacaaaag aaggcagtta aagatgaaca gaggaaccaa 291180 taagacatat agaaaacaga taggaaaatg acagacataa acccagccat atgacaatta 291240 tattaaattt ttaagagatt aggaaattcc gttgtttttt aaacatgagc aactatacgc 291300 tgtctacaga agagacactt tagaacaaaa gatacaaata gttggaaagt aaaaagatgg 291360 aaaaagctat atccagcgaa tccagaagag agcagaagtg gctattctga catcagaaaa 291420 aagagacttt aagataaagt attgctagag aggaagaagg atagtattta atgatagaag 291480 ggttaatatg gaatatgtaa caattacaat catatcagca ctaacaacag tgcccaaaac 291540 tacatacact gaaatttaac atgattgagg ggatcaatag gcaattcaac aataaaagct 291600 tttgttcata ccctcttctt aatcagtgat aagtcaatta gatagagcat cattgaggtt 291660 acaacatact tcagcaatgt tgtcaaccaa tttgacctga gatagataga tagacagtta 291720 gacagacaga cagacagaca gagaaaactt cacccaacaa cagaaataca aattattttc 291780 aagcatacct ggaacattct ccaggataga gtatatgtta ggctataaaa ctgtactcaa 291840 taaatttaag attgaaacca tgtagagtat gttgtgtgac catagaggaa ttagaaatca 291900 acacagaaat aaatttggag gtcacaagat atttggaaat taacacactt tacagagccc 291960 attggtcaaa aatatatata ttaaactaga aaggccgggg gtggttgctt acacctgtaa 292020 ttccagcact ttgggaggcg taggtgggca catcacttga ggccaggagt tcaagaccaa 292080 cctgggcaac atggcaaaac cccatctcta caaaaaaata caaaaaatga gttgagcatg 292140 gtggtgcatg cctgtagtcc cagctactca ggaggctgag gtaggggaat cacctgagcc 292200 cagcaggtag aagctgcatt gaaccaagat tgcaccactg cataccagcc tgggcgacaa 292260 agtgagaccc tgtctaaaaa ataaaaggaa tccagaaaac atcttgcata gaatttgata 292320 caactaaaga catgcttaga gggatattta tagttttaaa taactgtatc agaaaaaaag 292380 ggaagataaa taaatgacat aagcttccac cttaagaaac aagaaaaaga ctaaactaga 292440 agatgaaatc caaagcaagc agaaagaagt aaacaatagg gattggagca aaaattgatg 292500 acataaaaaa ccagacaaaa tacagagaaa aatccatgaa accaaaagtt gggtttgtgc 292560 agagatttgt gaaatttaca atcctttagc tagactgaca cagatcatta gaattaggaa 292620 tgatggagac aacatcacta ctgaccctat agattggatc aggaatgtcg ctgtttgctg 292680 cattgtgctt tcttgagggg agagctatga aggaaaacaa agttctcatt gcacttacaa 292740 ctcaacaaca cagcgttgac attttgattc tcactggctt cagtgctcat ctctgtgagg 292800 tttccagaag atcccgtagc aatatcactc attctaaatt tatctttggg ctactctggg 292860 aacgctgtct atgggttagc cctgctctgc aaggagcagt aagaaaatat atatatattt 292920 tttgaggctg agtctcgctc tatcgcccag acgggagtgc agtggcacga tgttggctca 292980 ctgcaacctc cacctccagg gttcaagcga ttctcctgcc tcagcctccc aagtagctgg 293040 gattacaggc acgtgccacc acacaccgct aatttttgtg tttttgtaga gacagggttt 293100 caccatgtgg gccaggctgg tctcaaactc ccaacctcag gtgatctgcc ctccttggcc 293160 tcccaaagtg cagggattac aggcatgatc cactgtgcct ggcaagtatg tttgtagcca 293220 gtggggaatt attttaacta ggcaataatt tgatctattt tgggaagcct cttgtaatca 293280 aatcatatat caacattaat cacatggtga gtcctccatg gttttcattc ctagagattc 293340 taggatgttt gacatttctc tgcttagctt atagcagaaa ggtattggat atcaagaatg 293400 tttgaacagt ttctcctttt tgggaatgaa gatgaaattg ggctagaatg agatgtgtga 293460 ttgagagaat gtccctgagg cctgagcagt gtgtcctttt gggtatgggc attggaagca 293520 tgtagtgaat tcttataatt ttatgttgcc tcggcatcca tcttgagtat aagtttaact 293580 ttgttatacc agaagcaagg cttactcact tttgcacagt ttccagttct acacctcctt 293640 ctcgttcctc agtgtgattg gtccagatag ctgccttatc caactgcctc ctttggacca 293700 cttcatcatg ggacagcttg atgcaatcta cttgacaaga ccctggaacc ccacacccct 293760 catggaacca gtgtccacct cccagtcaca gtgtgacccc agggaactct tgcctgcttg 293820 ctttaaaccc accacttaaa agtctccaca gaaaacctgt ttgaatagta cccttgaccc 293880 aataagggca ttggcccctg ggtgtctctc tctctctctc tctctctctc tccctctctc 293940 tccctctctc tctctcgctc cctgacctct gcgtgtggac tccaggcatg ccatataccc 294000 ctcaggacct gtaagtaata ctatctttat ttttatttta tatctctcct aatcattgaa 294060 aaggtgctct ctatcttgaa gatactatat taaataaaat gagaacttgt ccctaacaca 294120 gttagtgata ggctgaaaca cgctgattgc actctttacc catttagtga tttttctcaa 294180 gttactctac accatgtatt atcaacataa ttgatattac agaatagaat tataagacac 294240 ttcttttgcc acagaaagtt ctattggact cagattatct agagctacta catgtatgct 294300 attctatgat aaaagatgta gatgtgataa aaacatttat aaaatatctg tcttagaaaa 294360 gttagctaaa attattttgg gaaaagtatg tttgaaaata gaatcgtaag ctaccacatt 294420 gtgataaata tttctaaatg tgtctattaa cttgtcagga gacaacagag tgaattaaaa 294480 cagtagcctt gtatcagtat gtttttattc agaagacaaa tgcacgtttt aactattata 294540 tgttcttggc ttaacttttt ttgtaaagtt aagacattac acttttacat gaatctgtaa 294600 tttcaagata tcttaatggt tgacagggac aggacaattg aagaaaacct gtaaatacat 294660 ttggtaaaat ttatgatgga ttgttttgca gatggcttca gaggttatta gcacatctgt 294720 ttgagatatg cacagtttta catttgtccc ttaggtaatc aacagggctg agatcagtaa 294780 atcacatgta agccactgtt atgaggctat tctgaataga gttacatcat tttatcatat 294840 ctagactttc tagttatatt ggtgctgttg aaaatgattt tgtattacat gctttcttcc 294900 aaatcataga tcaagatatt ttatttatgt atgtctttta aatgaagagt ggttaggata 294960 gtcctgatta ttgcacataa atattgcctt tcactagatt attgttttgg gccaaatttt 295020 agactattat tttaaaaaag agtaccttag tttaatccaa cctttccaga tacttagaaa 295080 ttattgaaat gtatattttg tgaagatggt cttatgaaag ttgttgagct agaaacatgt 295140 ccttcaccag tggaattctt agaagctttc cttgggcttc actgggtgct aatagaccat 295200 gatcgtattg ctctgtatat aatggtacaa attttgtttt ataacactca gtcttaatag 295260 aatgggaata ttttatctta ctaacgtagt cattagctgg ccactctctg tgtccattgg 295320 accttatagg gtaaagggag ggcagtgcgt atttgaagcc tgtgcacgtg acacacaaag 295380 ggcttagcaa cctccgtgtt ttcccagcac aggataccca ttcttcctga atgtttcatt 295440 gttaaattag attgtgtgtg tgtgtgtgtg tgtgtgtgtg tattttatat taacatacag 295500 atgtatgtat tttagttgca ttttttttct taaaatgtta ttttttctct ttttctttta 295560 tgtcaggtga tgatagagcc cctagggaag caaaactgtc catgcccttg ccttaacttt 295620 cagatacgat aaaaacaaca tttataaaat acctgtctta gaaatattag ctaaaattat 295680 gttggggaaa gtatgtttga aaatagaatt gtaagctacc acattgtgat aaatattact 295740 aaatttgttt attgacttgt caggaagcaa aagaatgaat taaagaaaac tccagagaat 295800 gagctgacaa cctactccct ggtcagtggc tctccatgcc tacctgtggt ctcttggaca 295860 cccttgcagg tatgtgggca gggaactgca tgtttatagg aaacaggcct aggatggaag 295920 gagttaatag atcttgctct tcttgagttt gatgacattt gtttccagtt aaatagcatg 295980 aaaacccatc tgagagccag ctgagggtgg atacagttct ggggagttaa agacgagtgg 296040 tcacaacagg tcttcctcgg caatccgagc ccaaaactga atctgcctcc ataagaccat 296100 tatgtgtcag ctctttattt atatgattga ttcatccagt ggacttttaa tttcttatgt 296160 ccagatattt tttcagttct ttttttcgtg atacaagcac cttgtggatt gcctgtcata 296220 gaacaggttc tcaataaact tttattgaaa aaagatgtat aagtagattg tcttgagtaa 296280 ttttgtgaat aacctgacca actaagcagt agaagacaaa tgattttaaa acagaaagag 296340 acataacttt cagtgggatt caggtgatct agtcgggtct ggaaatgcgc aagagagaag 296400 gtccctgatg cagtgtgctg acattgaaat gtgtagttgt ggactagatg gttatggttt 296460 cagaactgtg taagtaaggg gtagattcca aattaaatca atattaaaga gtagcagaga 296520 aggaatttcc agattccagc tgcattgctt gtttcattgg aagtggtgtt tctctttttt 296580 cttttttttc tttctttttt tttttttttt ttaaacctca gaagatgact tcctgggaac 296640 tcttctggga gtgaatgtta tcagcaaatt cccaaaacaa caccccttag acaaaaagcc 296700 tcctcaccta tgcattgcct agaccaccca ctaaaggtaa gatgttagtt aaaatagtcc 296760 ttgctttctg ggagaagcca tgtcttagta gaaattgagc tgttaatttt ccgaatattg 296820 atgatgtttg attacattct aattgattct aagatttcat aatatgttaa gagatgcagc 296880 ttttcttata taccttcgtg gcttttctac atctcagtac atttactgtt aatatgaagg 296940 atttccataa cttctctcat ctagtaaact gaactccttc atggcttgat ccattgtgat 297000 gctagaaaat tgttgtacac agaagacaca gtagcctctc cataactgtt agactggaag 297060 tttgacaaac tggtctgaaa taactgatca aatcaatgaa tgacctagag ctttaagaaa 297120 ccagatggga agagacagac atgaaaccca aggttgttga tggctattac ttttgagccc 297180 agcaaaagga gaaaaagcag caccaatatc tggcatcctg gacatgagga agttttaatg 297240 tcattgtttt ggcctcatca tggacccagg tgctagaaat gagattttct ctgtgtactc 297300 tgggtatatt tgttctagca caagtagggg gaagattaaa gaggaatttc atacccccat 297360 gactccttag gaaatgtgtt tctcaccttt gccacttttc cccactgtgt ccttgcaggt 297420 gatggccaca aagaggtgga tttgttgagt tggtgccatt ccttctactg ccagcttcac 297480 caaaacaatg acacagtctt ccttccgcat ggagactctt ctctttcctg tgttgcagtg 297540 gatgcctcct gcagataaga aatgcttaac tgagaaatgc tcatgttggg atatcatcga 297600 tgagacttta atttgggcat ggtgactgtt tcccttgctg ccacttgact caatcccagg 297660 agcctcagta gaggatataa tattacacaa gatgctcaaa atggtggaat tgctcagtgc 297720 tcccataaat atacatttat aattttcatt tgccacatgg taaactgaaa aatacagact 297780 atattaaaaa gaaactgcat gatttttttt caaaaattca aagcatattt aaataatata 297840 taaattaaat gccctcctct cttccaattc tgtccctata gttttcctct attaagtgaa 297900 ctacatgcat tcttttagtg gatagatgca cacaaacaca caagccatta tggggaagga 297960 tccacgtgtg tggccatatt gtaacacatt tttctgcaaa tcacctcttt catttaacag 298020 cccttattca atggcctttt tctttttcag tagtacatac acatctgtgt catttgttga 298080 atgacgacat gaatgttttg tagataaaat ataattaaat gttttaagca tttctcactc 298140 atagatattt atgttagcac caaatttctg tgcaatgaac ctccctatat atcagtaatt 298200 ttgcatttgt ctataatatc ataataaatt acttatcagt tgaattactg ggattaagta 298260 tgtgcacact ttatatttat attttgaaaa ttattgcaag attgccttca aaaatgtggt 298320 taacaacttt atcttcaaat ggcaatgaat gagattgcca gctttcctac agcctcacag 298380 acaatggatt ttataaatat ttaacatttt tgccaatgtg atcacccaaa ctattgtctt 298440 aaattgtatc tcttttgttt ttgagtttgg tcattttttc atgtttatta gccatctgta 298500 ttttttaatt tcttctttat gtccaatttt gtgggtggga ggaggattta gtctcttcct 298560 gatttcgaag agctcattta ctatttcggg aaataagatt tggattgtca accattatag 298620 ctatttttta cacacttttc aactttgttt ttgttataag aatgtgtatg attgttacat 298680 gtccaagtat aaccatgttc gcttttatgg cttctgagtt tcatgtcatt tttggaaaga 298740 tatatatatt gagtccataa aacccttcac ctatgttaaa ttctaattct tttgtgtttt 298800 tttaattcaa attcttaaat catgagaaat ttttttgttt tgaaatctta aagttgccaa 298860 gttacttgcc attacttgcg attatttgcc aataattgcc catttatctg taccgccatc 298920 ttgcgcatat gctgtactct catctgtgac tggctccatt tttgttctgt ggatttgtgt 298980 gtctcttctt ctgcctcctg tctcgtgtct gctcgttgga agaaattaca gtttagactg 299040 caatttcatc aactttaata aatcaattga ggggagaatt ggtttttaaa aatattaagt 299100 aagtcttcgt atccaaggac aaggtatgtc ttttcttatt caataatttt aattactgtt 299160 aatattttca ctgtggtgat gggagttttt cttttaattt attttcttgt tcattttttg 299220 tatctaaagt ttttgttttg ttttgttttg ggggtaagtt gtcaccttac tgtttcttgt 299280 tgcttttcag attttttcaa agtatagact aaatccttca caaatattta aagtttttat 299340 tttccccctt catattgatc ctgattttag ttatgttgac aaagtccaca gactgttact 299400 atcagaacac ttgaacagtt atggaaatat tacctaccct tgatttaatc agagtttaat 299460 ggtatgcttc tttggtttga ctggcacatt gtcgctggtc atttcctccc aaagaccacc 299520 agaaagagct atgatcaagc aaagctgagt ttgttaaact tacctgcagc aagggaaaac 299580 accaccttga tagggtttaa taatgtttca aaatcaagaa atgaggcttt ggggtctggg 299640 cagggaacta attagaaatg ggcaaaattt gtcatgcaat accttgtggg aaagtgagat 299700 gaggttctta atgtgagtat tgatggtgaa atcattttct aggtgagctg tttgcctata 299760 taaagatgtt atcaatgaca gaagaactat ttgcctagat aaacaaactg aatttattta 299820 ttggtttaca gttttatctt gctgggcagg actctgctgg gggtggtatc aggtcttatt 299880 cccaataggt aagttatttg gatatgggtg gtcttaatca tcaatgtgta aaatgctgat 299940 tttaagtgcg aaatactttg tctaccatgt taggaaagtc tgccaccttt tatctttttt 300000 aaggaatttt aatcaaaacc aggtggtaga tataatcaaa ttgttttgca gaatcaattt 300060 tcctgttctc tttaaagact tttatcactg tgaattaatt tactattatt gcaacttcct 300120 ttaattcctt gaatgaacag accctactgg ttttaaaaat gttttattct tttaatttac 300180 tacttaattg tgggtatttt aatttgattt ggaattttta caagtataca actaagtgaa 300240 attgatctgt gatttttctt ttttgtgcta tttttgtcat gttttgatat cagatattct 300300 ggttgtgtta aaataatttt gaggattttc ttcttatact gtgttctaga gtgggtaaaa 300360 aagccctagt ctcactatca gtgtttaagt gaacacatca gtgacatcat ctggactctc 300420 ctttgttttt gctggtttgg agttaggaca tctagaagtt tttttctttt tttccttttt 300480 ttgtatggtt attgcttgtt ctttgttttg tgtcaaattt aacctgtttt ctcttagcaa 300540 atcacagctc atgcagattt tcaaacacat tagccttgtt atacaaagtg ttctttcatc 300600 attctattaa atttccattt tcattccagt tatagttatt tctgctgtgc ctttgttaat 300660 gaataagttt aaacagtgga tgtttagcat cactagcctt ccccttccat ctcccttaat 300720 caggaccttg gtataattta tcaggtattt tttaaggttc taatttactt atatatattg 300780 tttctgtatt cttttgtttc ttttcttaat aaattcttaa acctgtgtaa cacattcata 300840 ttcacttgtt cttggcaatg aaagatttac cctgctgtgc attttataaa acttgtcatt 300900 atgaacacat tgtaaacata cagtgtatga agagaagaaa acagtgaact agcacataca 300960 aggaactgga actggttcca tcattatcag tattttgcca tatttacttt gtgtttattt 301020 taagtatttt caaataagct agagaaatct taacgcttct tattctccca taaacatttt 301080 tacaatttta tttttgaatg tgtatgtata cacattcgta tgcttttata ttgttctata 301140 actttctttt atatcatgta atatataaat attttaatat ttctatctga ttattacata 301200 tccatagatg tgaagcttcc ctatttttaa taacttatat ttttacataa gtaaaattta 301260 catagttaaa tgcattgata tatagtaatt gtataattca ataagtttct taaaagtaat 301320 tactatccca ttcaggagat agaatatttt tattacttga gaacctaccc tattgcctct 301380 ttccaaccaa gcaccttctc aaaaaaacaa tgttgtgatt tttatgatca tagataagtt 301440 ttgcctgttt ggaaattaat ataaatggaa tcacacagtg tgtgtctggc ttcttgcact 301500 catcataatc atgttgagat ttatctgtgc tattccctat atcagcagtt taaaaaagtt 301560 tctatagttg taatatttca ctaaatggtt atattgcagt ttatctattc tcttgttgac 301620 ggacacctga gtagtttcta gtttttagct gttttgaatg ttagcagatc tcttatgtaa 301680 atacctaaaa attgaattgt ttgatcataa gacagatttt gcttaactta taggaaactg 301740 ctagagagtc ttctaaagag atggacactt ttcgcactcc caaccagtga tatgagattt 301800 ttagttgctg tccatttttg ccaacattgg aaattgtcag tcttatctat taagtgggtg 301860 tgaggtgata ttttgttgtg acttcaattt gaaatttgac cacttaagaa ggcaaccagt 301920 ttttcatgaa gttatccaat tgtaaatctt ctttagtaaa atttgtatat ttttcccaac 301980 ttttaaatta caattttgaa gtaattttgg acttacggga aatttgcaaa aatagtagag 302040 ttcctgtgta ttctgtaccc agctttctgg atgttagcat tttatataat cattattata 302100 acattattac atacaatgat aattgaaatc aggaaattaa tataatactg tcaaccaatc 302160 tgcagactat attcaggttt ttcaagttat gctactaatg tcctttttat ctagtccagg 302220 atccaattca agatctctta ttttatctgg catgtttcct ttgccctctc tcctgactac 302280 aaatctggga gagctccctc agtctttctt tgtatttcat ttaattgaca catttgagaa 302340 atactagacc ataatttggt acactagtcc tcaatttgga tttgtccgat atttttatta 302400 ttagattaag gttatgcact tttgacaaaa gataacacag tagtaacagt gtgccctttt 302460 cagtggatca tctggagtac atgaagttaa tgtcttattt ctgctgatac taaatatgac 302520 gcctttatta aggtagtgtc tgccaggttt atccactgca aagttactgt tttcctttct 302580 ttgtaattaa tattttatga gaaaataatt tgagactatg caaatatttt atttcatcta 302640 atttcagtat taattgaaga ttcttgcctg cagcaattat gattatggtg tttacctagt 302700 aatggtttct atttccatga tactttctct acttactaga atttgactgt aaggaagatc 302760 tgtccttctt ccccatttat ttgtactcag ttgttatttt acatcagtat ggatttgtgg 302820 atatcttatt ttatggattg ttatatattg caatcattgt ttgtgtttga ttttcaattt 302880 tttttctgga tttgatcatt gggagctcct taaagttggc ccctgtgttc ttttaataca 302940 acctcataat tttttgacca cttcttattt tcgggtatca caagatattc taggtttatc 303000 ttgtattttc cttccccacg cctgtaatca accatttcct caaggggttc tagttcttca 303060 tattggaaaa tagtatttag aaaccaagat cttggtatta agtgtattaa ttgctaatgg 303120 ggttttattg cttctaggcc tagagctggg agctgtgtgt ccgtttacac acatacacat 303180 acacacacac ccctatattg tctctattca tttatctatc ttaaatatat atactaatag 303240 tatgtagaat actatagata gtatatatct atctttatta aaaatcacaa gttcatactg 303300 ttgtggatca taatccatca tcatatggtt cattttattc ttccctcttg gcttatttgt 303360 gatttgcttc ttcaacagtg agaaacctac ctttcattat ctacaatatg ttttgttatt 303420 tcttcagtgc agtatacact taaataattt cagaattgct aaattatacc cctttaaaaa 303480 tgaaatcact aactacagca cagtatttaa atatagttct tttgtcttta tccttaacag 303540 cgttcagtca acatactatt atttctaaac gtatttaggt tagttatctt ttttttccta 303600 tcccctgcca tatggttaca ttaatcatat aatcaagcag gtttttttat tgtttatatt 303660 ccattttgag ttccctcacc ttttggatta ttttaactat attttgtata tgtgaaatat 303720 tactatgttt ctaaaaatta ggactgtgag aaataccact ctcccatcat ccctgctaca 303780 ctgattctat tcctcccttc tttccaccct aatctcaccc aacccttaga gttaactagt 303840 ctaatagttt ctggtttatt tttttctctt gttattcttg ttcacaagtg ggcagataca 303900 tgtatatttt atcatatatc acatgtatat tttatatccc cttccttctt acatgattag 303960 tggcatacta tagatttttt tttgttgcag ttttcttttt ccgcttaata tgtcctggaa 304020 atcacttcat gtgtattcaa agagatattc ctcattctgt catgcttagt gcttaactcc 304080 atggatgcac cacaatttat tcaacccctc tgctctatga gaattgtttg caatatgtgt 304140 aaagtatcac actacaaata gttttacatt ggattgttta tttgctcttc gtttggaagt 304200 gttctttgta ttactgggac atacatttct tgttcaatat atgtgttgca aaggtttctt 304260 tcattaagta tcttagcctg cctgccttcc tttccatttc ctttcttttt cttttctttc 304320 ttctcctttt aatgctgtta tgctctaaat tttaaaatgg cccgaatttg ccagtggctc 304380 atcccttatt gctatttatt cttcctctcc ttttctcccc catctctttt cctttaattt 304440 acgtgaaatt aacataacgt agccatttag tgcattcaaa atgttttgca actgccatcc 304500 ttaactagtt ccaaaacatt ttcagcaccc caaagacaac ccatacccat taagcagtca 304560 gtcccaactc tctttcccca tcttttcatt tttgtttttt ggagtttttt tgagacaaag 304620 tctcactttg cacccaggct ggagtgcaat ggcacaatca tagctcactg cagcctcaaa 304680 ttcctgggct tatgcaatac ttccacctta gcctcccgag cagctaggac tacaggcata 304740 tgtcaccaca ccaggctaat ttataaaaaa aattttttag acacagagtc ttgcagtgtt 304800 gcccaggctt cttgtgtctt tcgataaaca gacattgaaa atttttaagt ccagtatatc 304860 agtttgagtc tcttattttt agtgcttatt acttactatt aaatctttgc ttactccagg 304920 tttgcaaata atagttttct aagttttctt ctagaagctt tgggacataa gtataacatc 304980 tatctcaaat cattttcaaa tgtagttgaa gttacttgtt ttcatcaatc tccagttgtt 305040 gcagaaccat ttgatcaaaa gatttttctt tttctactga attatctaat gccattgttg 305100 aaaataagtt ggccatttac gtatggatct tttttgaact ctctgttttt ccttctttat 305160 gccattcttt ttcactgaag tttaatagta aatcttgaga ttaagtagtg tgagtccaaa 305220 attttgttat ttcaaggctt tatagaggaa ggagatggct acactgggtc ctttgtatgt 305280 tcacttaaat tttaaaatta tcttgtcaat ttcctaaaaa gcccaaccga gaaattgatt 305340 ttgattacat caaaactata gataaattta ggggggattg acatcttaac aatgttgagt 305400 ctgtagttct ccatttatta ggtcgtctat aatttctcat agatgtcttt tatggtgttt 305460 agtatagaag cataccttgt agttttcaat atagaaacat tattaaaatt taacatttaa 305520 taaactagat taaattgtta aatttatttg ttttgttgtt ttgatgctat tgtaaatgaa 305580 tatgtttaaa tttcgttttc cagatttgtt actattatat gaaaacagta atattttcac 305640 attgcaactg cttttcagtt gggttgtctt cttttcagtc ttaggagaaa atatgtaatt 305700 tcttaccatt aagaaagata ctagctgtta tttttttgta gatgcccatt accaaattga 305760 gcaagtttta ttctagtgcc agtttgctgt taatttttat aataataatg tgataaattt 305820 gctgaatgtt tttctacatt tattaatata atcatgtttt cccccttatt ctcttattat 305880 gggagactgc attggtcagc ttttgaatgt tagcccaaca ttgcattctt gatgtaatcc 305940 aattggtcac tgttatcctt cttgtatata tattactgta ttcaattttt ctgctagtta 306000 tttaagagtt attcacctat gtccgtgatg gccattatcc tgtggtttcc tttttaaaaa 306060 ttatttttgt cagatgttgg cattaggctt cataaaatgt atttagtata gtgctctatt 306120 tgctagtaca cttgaccctt gaacaacaga catggagatt aggggttcag actcccccat 306180 agttgacaat ctgtggacaa ttgtttgctc tccagaaact taactacgaa tagcctactg 306240 ttgactgaaa gccttacaga taacataact agtcaattaa cacatatttt atgttatatg 306300 tattacatac tattttatta acaataaagt gaatgagaga taaaatgtta ttacgagaca 306360 taaggaagag aaaatatatt tactattcgt tacgtgaaag tagatgatca taaaggtctt 306420 cattctcatt tttatgttga ataggctgag gaggaggaag aagaggaggg gttgttctta 306480 ctgtatcggg gtggcagaag cagtacactt ggtgtaactg tatggaaata tagtttctag 306540 cttttttgat ttttcatttc tctaaaaatg tttctatatg gtacagtcct tcttccactg 306600 tttacttatt tgtagtaccc acatcataga aggagccata ttgtaaagaa gtcaaatgca 306660 gacttaaata attagaaacc ttctgccagc gtgtttttct ggcactcctt ctgtgtcgtc 306720 ttccttatcg tctggtactg gttcagaagc acttgtctcc atcacgtcat cttctgttaa 306780 ttcctctagt gtgttatcta ttagctcttg aatttctcca aggtgtatat cttgaaagcc 306840 ttcactcacc accctttttt ccgtgttcac gatctctttc gtgatttcct tggttggctg 306900 tattgtaaat cctgtcaagt catgcacaac atctggacac agtttcctcc agcaggggag 306960 tgtgttgtgt tgggcttgat gctttcacag ctttttgtgt aacgatggca tcttcagtgc 307020 tgtgatcctt ccagactttc atgatgttct atcagggttc tcttgcatag tgttagataa 307080 tcctttccat aaagtactgt gtgtaatgag ccttaatggt ccttatgact ccctgatcta 307140 gaggatgatt tagagatgtt atgtctgggg gcaaatagac cactttgaca ccttcagtat 307200 tgaactcatg gggtcaggga cattgtccaa tcaaaaaaaa aaactttaaa aggcactcac 307260 ttactgcaag gtacttcttg acatcagggt caaaacatca atgaaaccaa tacagaaaaa 307320 aagacttctt attgtccagg cctttttgtt ttacaatcaa aagaccggca gctggtgttt 307380 taacttttcc cttcgaggct caggagttag ctgctttata gataaggtca gtcctgatca 307440 taaacccaat tacatttgca caaaacagta gaattagccc atcccttcct gccttaaatc 307500 ctggtgctca cttctcttcc ttactaataa atgtcctttc tggcattttt tttttttcag 307560 agtagggcac tttcgtcagt ttaaaaacct gttcaggcag atatcctttc tcctcaatga 307620 ttttcttaat ggcatctggg aactgcttct cctgcttgac tgtttttaag ccagacttct 307680 ttctaaaatt atcaaaccat cctttgctgg cattaaattc tccagattta gaaccttcac 307740 cttccttttg cttaggatca tcttgcaccc tagaggtatg ccttacagca atcctgtacc 307800 cgcagaaaag atgcattttc aatagataga tactttgcaa aagtgcaagg ttttcacagt 307860 gttggtacag ctgcaacaat ggcttcatga atttcctttt tttttttttt ttttttaaca 307920 attgtcctca cactggattt acttatcttg aaatggcaag tagcccctgc tggagacctc 307980 aatctgtggt accttttaag caattaaacg ttttcttgta atgtcatgac tttcctctgc 308040 ttcttaggag tacttccagt atcaccagtg gcacttcata tgggtcccat ggtgttaagg 308100 tttatggtat tacacaagac actatgaaaa gtaatatgag aactgtgaaa gcttttgttt 308160 tgctgccaca tgcaatttac tggagggaga aactgtttcc tggcatgatt tcgggtcacc 308220 tggcacttta agcagatgca attgagctcc ccactgtagc aaaaggaggt ggctacaaaa 308280 ttattacaat aatgctgggt gtactacagc taattttatg cagttaggat ttaataccac 308340 atatttacat ttctctcaac tgcaaatggc accatgtagg atctgtgagt atgtgtgagt 308400 aggttttgat aaattttaac tttttataat ttgtgtatat tttatggtaa taaatgataa 308460 aaataggcta gtatctacat ctattttatg cattcatgac ataccttttt cttaattttt 308520 ttggtatttc tggactacgc agttgagttt tttcaaattg tcacaaattt ccaaaaatgt 308580 atccaatgta tttattgaaa aaagtctgca tataaataga tcatatgcag ttcaaacttg 308640 tgctgttcaa aggtcaaatt tctttgtgga atgtttgata gaattcatta gtgaaatgat 308700 ctgggcctgg agtttccttc gtgatatttt aatgaacaat ttcagtttat ttaataatac 308760 aggattgaga gtttctgttt catttaatgg cagctttagt actgtttttc aaagagtata 308820 gtccatttta tcagatttgt caaattcagt agtataaagt tgctcatgat agttccttat 308880 tacccttata ctgtctgtaa gatctcacct ttccaattct gatataggta atattatttt 308940 ttctcaggtt ggtctttttt tttttttttt tttttaacta tcttgtcatt taaaagaatc 309000 aatctttgat ttgctaattt tctctttatc tgttttttat attattgatt tctttccttc 309060 atcttacctt ggttttaata tgctcttttt tttggtagct tcttaatctt gagactatta 309120 agtcttctat tatgtacctt acttattttc taatataacc attgaaggct ataagcacta 309180 cattgataga ttccacaaac tttgatatat tgttttaatt accatttaat tcaattattt 309240 tcttcctttg tgttttaatt tgatctgtta tttttaagtg gagtatttaa tttccaaata 309300 tttggggctt ttctgtgtag tttgttacaa cttctgtttt agttttgttt tggttctaaa 309360 aagttactct gatatttcag ctttccaaat ttattgagac ttatggtcta gcatatgatc 309420 tgtcttgaca aaagtttcac atgcacagga atatatattt aaactcaagg tgtgcagatt 309480 ttgttcagat agatagtgtc tagattttct agattgtcag tgaattttta caattgtttt 309540 ataagttaca aagagaatag tgtaaaaaat ttctgctgtg attatgattt tctttatctt 309600 tagttctctc agttcttcgt gtatttggaa atatcttatt gtttatactt ttatgaacat 309660 catgactgta ataaatttta tcttttccta atttggcctg tcttacctta tgtaatattt 309720 ctggtcttga tgtctgcttc gtctgatatc tgaataatat taccagtttt cttgggtttg 309780 cagtatgtct ggtgtatctt tttctgttct ttaaatctgt cttcatagtg cttccattat 309840 agagagcata gagatggatc ttttttgtcc aatttaacca tcagtgactt ttaagtcttt 309900 ggggtcttaa gtccctttgc attaaacata ctaacgtgac tagacttatg cctactattt 309960 agctattgtt tttccatttg tcccctctag tttgttcctc tctgcctgct ttgcttcgtt 310020 cttttgggtt aattgaatat ttttagtatc ctacattaac ttctctgttt acatttcggc 310080 tccacctctg ggtattttgt atgggttata aaatgtaccc ttaatttatg acaatctgct 310140 tagagttagt attgtacact tctcatgaag taaaatttta tatatatata tatatatata 310200 tatatatata tatatatata tatatatata tatgagggag tctcaatctg tcacccagac 310260 tggagtgcgg gggcatgatc tcagctcact gcaacattag gtggaactgt attaactcta 310320 aaaggactgt gataatttaa agatgtatat tataaccata gaataatcac taaaaagtac 310380 agagaaatat agctaaaaaa gcaacagcag aattaaaatg taatagtaaa aatacttgat 310440 taaaagaata caggaaagaa tgaagaaaag aacaaagtaa actgtataga aaacagatgg 310500 caaaatggta gacctaaaca cagtcatatt ataaattact ttaacggtac acttgttttt 310560 cattgcttta attgatcaaa tgataggtaa agtattttaa agtctctttg tagttttctt 310620 taaatcttaa cattttgtgc aatgtttgct ttgtgaagat tgatgctatg atatttacca 310680 atcatttaga agagatattg ctgggtgttt tggtaagttt aggttactta catatcttat 310740 atgatgaaat caacattttt tatttgatca acttaataga ggcatcctgt ttgaaagaag 310800 aaaataacag atctacaaaa ttctgattca tgtaataagt aaccattatg ataataaatg 310860 tttttattta ttgagtgcat actgaaaagt ggtaggaaga ttttgtgctg aaatatttgt 310920 aaacctagta attaaaaaat gttttggctg ggcttgttgg ctcacgcctg taatcccagc 310980 tctttgggag gccgaggggg gtggatcact tgaggtcagg agttcgagtt cgagaccagc 311040 ctggccaata tggtgaaacc ctgtctctac taaaaatata aaaattagcc aggcatggtg 311100 gtgcacgcct gtagtcccag ctactcggga ggctgagatg ggagagtcgc ttgaacccag 311160 gaagcagagg ttgccgtgag tcaagattac accattgcac tccagcctgg gtgtcgcagt 311220 gagactctgc ctcaaaaaaa aaaaaaaaaa aaaagctgct aattacccca tgctaaatgt 311280 gttgtaatgg tattaatttg atatataaca tatatgtaac attttatata tgtgctcata 311340 tgatgatact gataatacct ccctcaaatt gctcttttga gtattaagaa aagtttatat 311400 agaaaaacca gtttggaaag gtttggaaca taaggctaca gtgattagat gttgagaaca 311460 gcagcaataa tagttgtcat tataatatct gattaaggca atatttgcac ccaggtatac 311520 cttgcttcag aactgtgtga ttaaccatta taccttgagg ctattcatac cctaccttca 311580 ctttgttggc ataatctgaa gttttaaacc ataatcacat attgcatttg cacaattaaa 311640 ttttaaaata tatacaaatt acagtcaaat tattgcattc atttcatgac tatattctgt 311700 ttccatccat aagtaccgta tggtcaacaa taacatgtca aagagaattt tgttgtcacc 311760 tcgtttcatt gtaccatgtt cacactgttc tttatctctt ttttccattg gcagtattgt 311820 gttctcaaga agaattattc cagaagcacc cctgaaataa tatatttcct taattttggt 311880 attattagcc cttctttgct tttctctata aattgtcctg atcagtcacc tctctcaatt 311940 atatacaaca caaagtagct taaaggagaa aaaaaaggag ataaataacc atgttgggtc 312000 tggcgtcagg cttaatggag tccagtagtc cagaatttaa agacacatat gaccgtttgc 312060 tcccttatct cttagttctc catttcttgg tttggcttaa atcttcagtc actttttctt 312120 tatgtgaatt tgcaaaggga tcatttgaag ccctagatgc aattattacc tgccttgcaa 312180 tcttggtagg atgtgtcctc cttccctcct ccttgtccat gtaaaagttg gtgggtgaag 312240 agatggacaa ggcttgagtc actaagacat tcactgacct gggaataact caggataggt 312300 ctggtcatat ccccaatgga ggcaatgtac cctaatgaaa aggtcagggt cactggtctc 312360 attgtccaag gtgttatctg agctcatggt ctcacaacca agaaaattaa ggagtatgga 312420 cacagggtga ggttggttgg agcaaaagtt tagtaagcga aagaagaaag ctctctgcag 312480 cagagagggg agtccaagtg gattgccgtt tttacagtca ttcaaaagct tttttaagaa 312540 actcctctca tctctgtagc actttgagta acttctctta tcagcaaagc tgtctgtaca 312600 actcccctta tcttatgcag ctgtgggtat gtctctaggc aagcacaaag cgccgcttat 312660 ttttgtttgt gtaactgagg gtttgtttta ggtaagcccc ctcctttctg tgcaggcttc 312720 cagggagccc accatgtaca tatctgaaaa gggaaggaaa ctttttgctg ggagcttgtt 312780 aatcatacaa agaataaagg gcttccatgc cagactttgc ctgcctgctt atctatggct 312840 tatctgtgca gctatagcct gagtttcccc tggctgctct gtttttgcct gtagctgtga 312900 ttttttcagg cagacagctt ctctgaggac tagtctctta gctgtttact caagtaattt 312960 ttcctgtcct tttccctcac tatgattacc agctccccta ggacttcatg gtctggaatg 313020 aaatattccg tgggagtcag ggaaagggag tttgttgcaa acatgtccag gccagacact 313080 ttatataaag tgtcaaagta aagtacactt acataaagtg taagtgctgc caccaccact 313140 agggtgccag gtactctaac acaagtcttt attcccatag atgtgagtta acatttatac 313200 caccagctca cactatcaaa caatcccacg taccccaaat aaacactggt gcctggtggg 313260 cagcaacaag ccctccttca aggaaggagt tcatttgttg gtttatccag ctgctcccgc 313320 tttgcttatg gaagcgctcc gttttctagg ggtcttagaa gctgtagcag tggtagaaag 313380 cccctttttt gtggactatt atgacttagg cttttatcag agcctcagag aattgctgtt 313440 gttttgttgg ttaggcttta ggtttccaat ctgcatacac aattcctttg aagcaccagg 313500 cttccaggca atttggttga gggaacttat tgggatatga aatattatca ggcaccattt 313560 ctaatcaatg tacctaagtt atgacttcag gtttagagaa aaaaaaaatt tttttccctt 313620 ggcttcaggc ttccttctgg aggtgataac ctcctaaatg gactgtcttt aagggcctgt 313680 ggcatgtgcc ctcctttcag gaaactagtg tatgcctgga ggcattggta atggcttctc 313740 tcatcttact gtggcttggg aagaatatgg ctattgcaga ttttctagtt tcattaccac 313800 ctgaccttca ggctccttac atgttatagg cagaaaaggt gcctccacaa agttgtgggc 313860 tattctctgc tttcagaagg acagctggaa atggtactta attctttgta gcagcaccat 313920 catgaatagc tgcccacacc catatacatc attatctttt ttggtgaaga ctctaagact 313980 tcaggccatg atatccacaa ggctatgttc atgcactact tcggtataat ctcaaaataa 314040 ttgccagctc cccagtggaa cgcctgcctt ggtccatgtg gaatgtgggc atatggtagg 314100 atttccttgg aggaactaga agaggaacat aaagaatgtt aggcatataa attattgttt 314160 ctttttcttc ttgtttcttt ccactgagtt atgtgtgagc ccccacaccc accctacctt 314220 cctgtcctct accttactga tgctattttc aggctgttgt agaattgggt gtgtaaaatt 314280 aaattagcct ttctcctctt aatatctgta aaatgaacaa atttgacaaa gaaactacct 314340 atctgatata taagaaggtt attagcctgt accacaagtg aaaaagtttc atcctgatat 314400 atcaaaatag taccacttga aggaaaacgt tggggccatc tgtttctctc attgtagtta 314460 gagtacagat ttttaaaata tgagcctcag gcataaaaat gcagtattag caactcaact 314520 tgaagaagca gttactagtg tcctgggtgg gccccaggga aaatagtacc aactgcctgt 314580 tatatttaac tgcaattaaa aatggcagtg ctgggtatct tctgtctctg ggtcatctcc 314640 taaagatcct gcagagggag ccatagctag tgtagaggcc agccataact agccatggca 314700 aagaccacag ggaacgctct tcaacatgct ctgcactgat cctctaccct ggtgtggaga 314760 aatgtcagat tcatcactaa caaggttaaa ggtgtaaatt gagggaaaaa aatgagaaaa 314820 gttatctttc acataagact tcagaaagaa attgcgtcgt caggtttgga actggtttgt 314880 aatttcatcc agttattttc attttaatta ctgtcactgt tttcttcatc cttgataaac 314940 tatgagctct ttgagattgt ctttttcata tcctgatgtc agagcttcct gtattttctg 315000 atcatggtat gtgctaagta aatgcaattt ttagcatttt gaatggttta tcaaatgatt 315060 gaaggagtgg gtaataatat agattacata tacagtcagc cacatatgtg tatgtatgtg 315120 tatttgtgtg tgtgtgtgta tatgtatata ctgttgaccc tccgtatcaa tgggtttcac 315180 atttgtggat tcatccaatc atggatcaaa aatattcttt aaaaatatgg ttgcatctgt 315240 actgaacagg cacaaacttt ttttcttatc attattccct aaacaatgca gtatgacaac 315300 tatttatcat agcattgaca ctgcattaga tatgataagt aatctagaga ttaaagtata 315360 taggaggatg catgtggatc atatgcaaat aatacactac atcttatata agggacttga 315420 acatccatgg agtttggtat gtggtgggtg atacctcctc tttgaggagg tgagtatcag 315480 agacgcaggt aaatatgatc cagagggcaa agaggcattg ccagcctcac actggctgtc 315540 aacaccatgc tgagttccac gaaagcagcg aggagagggt ggtgttcttg tttctggtac 315600 aatacctggc atagagaaga tgtcacagca atgttcgtct attgaataag tcaccaaaat 315660 tgtgaatgac tgaataaatg ggcaaaggga tttgttccct acttgctgtg ggaagtttct 315720 tgtagttatg acctccatga aagagagact cgtatctgga gaaagttcat agctgaaacc 315780 atgagattta acttttgaag ttataatgga tctatttttt taacatcata aatgaagatt 315840 atgcaatact gtatgtgctt caattgacac aaccccttcc cattcagggc tgatttatgt 315900 tctgtactga atgacaggca cagaagtaaa tgtgataatc ctgtcccgtc gttacccttt 315960 attgtggtct tgctgtgtcc cagccacaca cttcatactg tatctgtgtc atcattctca 316020 tatacatcta tataggtaca cttccataga cttaggccca tttaatggag gagcaactcc 316080 aacatttaga gatcatgaaa ggtacctcat gacatatatt gacctagtgg cagagctgct 316140 tagttctaca gcctctgagt ggaatcctca cgacagtaaa aacacaagct tggtttctca 316200 cacactctac ctgctttttc tcatcccctt tagtctctat tccttgctga gatgtgttag 316260 gcattaaatg gttacagtct acttctgtgt gtagtctcca aacactcaga aacctcaaaa 316320 tttaaaaaaa tacagaacaa tatgttatta aataatcagg gacaagttaa aatggtaaag 316380 agaataggcc actttgtgaa atcatatgca gggaagaaaa aaatactgga gtgaaaacaa 316440 tataaaaata atactagatg ctgtttcgta gcaccaagtg tgttctagct tctgtggttg 316500 ttgctttata tcattttata taatctttac acaaaaccta caagcagata ttatttcccc 316560 tatttcaaaa atgagaaaac caaggcaaat agttggtaag tagtacatat atattatcct 316620 aactctgaac ttctggattc aaagaccatg ttctaggata ccattttgtg taccagcatg 316680 gaatatgttt ttagttcatc tatttactct aaaaatgtgg agcatgtagt gtgagacaga 316740 actgttctag gctgtgagga agtagctgtg aggatggtag tatgggtccc tgtaataatg 316800 aaaatggaat atattggtat gtacaagtac atgctcatta aaggaaattg atgttggcat 316860 agattgcctg ggttcaaatt cccatttacc atgttttcct agttgtctct gtggtgagag 316920 gaggtggaat gtactagcca ttaccaaaat taagagagat tgttggaaaa agtctcattt 316980 agcacaataa cacattaaat gtattcaata aatgttactt atgactcttt gagaaaacat 317040 acgtttaaaa aacatggctt atgttacaca tactatatgc tggctcccaa aaataaacat 317100 atttcccaag aagtgtctgt tgataaagcc aaatatattc ttactacact aaggggaagc 317160 ccatcttagc agtgtctcag cagcatatta ggggcgtggg ggacaaaaca ggatatctgg 317220 gatcttgaag tttcatttta gatgggtctt tcagtgtggg agcttgatta ggattgggtg 317280 agggtcatga cacagcattt taagattgaa cgttaggatt ttgagatgag ggattctaca 317340 gtgtggaggc ataagctgtg gtctgatgct ttctgttgat gagttgatgg tctttgggaa 317400 gttcccagga tgaacaaaaa tatttgcaac ttttatcttc ctgggcaaga gtctcagaac 317460 atctacactt atatcaatga aggtaaaatg ataataatgt ccccagcgaa gacaggaagc 317520 catgtgggta gataatgtaa gttgtgtcat ttcatggttc catggataag cagctgtact 317580 taagctgctt atcctggtgg attctggaga tccacacttg aaggtatcaa cacagaaata 317640 tactaagagg attgtggtca gagtttgttg tcagctactg agtgaggagc caggaacata 317700 cagcttttac caagaaaatc tataccatcc acactgtgat gagcccacaa gaccagatat 317760 gggactttag ccaaattacc taattttatt atgtctttga ttgctttctg gtccttatct 317820 gggatatcag agatcccaga gagatggcag ggatgcaaat taaacattct tcccccaaaa 317880 acaacacatt tttcccttat aaaattacta tattctgaaa aatttcatga acctccaagt 317940 caagatgggg cattgtctaa cttgcctgct gtttgctata caatagcatg gagtcagctc 318000 caggcttccc aaccctttcg aaaagcatga attgaagagg cttaaggaga gaagaaagca 318060 acccagaatt ccctgtgtgg ttacagtttg ggttcttgcc tcaaggcctg gtttttctct 318120 ttttggagta aagttatctg aagacctctt tttctaagag aagaaactaa tgggtcaaaa 318180 tggaccctgg gggatgtcag ggactacagt gaaggcagac gttagttcac ccctgaaata 318240 aatttctgtc cagtgtgcag acagtagcca gcagaccttt gtctccatca tccaatacca 318300 gtcttttcag atctagtcaa tgatctattt aaagccaaaa tatccttatg agactgtcaa 318360 atagtattgt atttttttgt atcactcgtc aagaatagct tagtacccgg caataaattt 318420 tatagtactg atattaatag atctcaggtg aaagaaaagt catgtgtctt ataagatggg 318480 tgaaagccac ctccaaatag atactctgtt ctctagttgt ttttcatgtt ctattcctct 318540 gtaagttcag ttacaaaagc tgacttccac aaaaagttct ccagtattgt tttggaacct 318600 tattttctaa tatcttgtca tatacgagtt gagtcccaat taatgattca ttatgaggaa 318660 ctggaaacga gaaactgagt ggctcaccaa ggaaaatatg tgcaaaccta acggacaatt 318720 tggttatatg atttaaccac tgcatgcata aattataact aggtattgga ctcatactga 318780 ggagtgatta aaatgtaact atgccttata agcaacataa ttaaatgtag ctttaagcca 318840 gataggcaag aaaataacaa aaggacgcag attaaaacat gacaatatat ggtattgttc 318900 tatgagtctt gagtggaaac tctacatttc atgcagtcat ctacttgggc taaaaatcat 318960 gtgtagtggc catctccttc caaagaccat cttacttcta atgagttctc attgaggtct 319020 cacgttctca gtctgaggtc tccaggtctc aagatttctc agcttgaggt ctccagtaat 319080 gatttaagat ggtttatgcc tctttgattg gaagacatca ctctcagtat caactccctg 319140 gaattttact tctggatgag tcgttaacag tatccgatag ggtcttttcc atcagggttc 319200 gagggctttc tttctcaggt atctctcctg gagatacctg agaccaagcc tctgaattta 319260 gaccatgtga gggtcattta gtagaggaaa agctgcttgt ttacctctta ataagactgg 319320 ataaattgcc tgagttacct gcaatatttg gctgtgatca cttccaataa tgtagagtct 319380 agaagcagag gagatattcc tagactcgtg ggttggcctg ttgctaactc aaaagggaag 319440 atttgatgaa ccccagaagt tgagctcatt gtcattaaag caaacattag gccatgtgag 319500 tttgagagtc tttgatagtt ttgctaattt gagcttaaac tttttgttta ttctttctat 319560 atttcctgaa gattagagta atatggacag cagcgtttct gtgtggactg gcagagctgt 319620 acaaagctct ttatcatctc agtaaaatgg agatagttta tacttgtact agagagagag 319680 tttgggaaca taaaatcatg tcaaattttg ctctggcaga gctggaaatc tccaaacaag 319740 gcctcaatct atcctccaaa taagcgaaca attaccatac atactcaaaa cccattgcag 319800 aaggtactta caaaatctgt aagtgttcta aggggccctg agattcttgt tcatgcccca 319860 tctttgcatt tttaccaaga ttatactggt aacaaataag acaccgcatg caacctcaat 319920 aatcttagtg aaatttctcc atcaatgttg attgagtgca gtagccaatt tttctttgct 319980 taggtagtta attgcatatt aaatgtttga aacatcccgt ttaaggtcct ctggcgctac 320040 taagcatcta tcctagagtg tgagagattt tcctcttgca atttacctgc agatttatat 320100 tagtaacggt ttgccaactg tggaaccaat tgttgacatt ctataagaac ctgtttgaac 320160 ccgtcagaag gtttgattat gaggaccagg atcttagtga gggctccatg ctggggcctc 320220 ctggtatccc catcttgtat tagtgtttgt ttttttaata gccacatctt tagcaagctt 320280 tacaatactc aaaagttctt ttatttgctg accattttta gtagaggctc ctgctgagat 320340 tgagaactct gtttgttcac aaacaagacc aagaactaca cacaaagcat acctgccacc 320400 agcactctcc tatctcactc aaactgacca gatctgtaga gcgaaatgag tcctgtcatc 320460 tggcagattt tgcctctggt agtgattata agggtgaagt atgtcacatc atgtgccatc 320520 tgatattctt ttgtcccagt cttaaagtac agcacatcaa agaacaagat gaaacatgga 320580 tttttaaaaa gagattacta atacatctat ttagggcata gtttgtaaac aaagacagta 320640 cacagcttct tcttaaggta atggaaaaag tagcaatttt gaaagtattg ccataagtaa 320700 taaagatgtg aggtgctgat gtgaagtaat atttcatagg aatttaagcc tctatgctga 320760 aaagtatgta ttttcaattt tgtgtatttt cagtaaaggt tatccagcaa gagggactat 320820 gaaacttaaa ggagacccta acctaaacca agccagcaga ggcttccagt aatttagctg 320880 ttgtggctat tgccactggg tgaagataca gacttcaatg agctggcccc tgaggattct 320940 cctgaaatgc atttagaaca ccaagagctt atccccagca ctcatataca aactggtaga 321000 gagttctgtg ataattaggt aggcctaaag tgggaggtca ttggaaggct aattttaact 321060 cacaaaaatc tctttgtgat taggttctta gggctcagtt ttggctactc ataaagtggg 321120 taagtcagag agatgggaaa ttttggaaaa ttttggaatg ttctgcaata agcatccaag 321180 gaaacccagg aatcctctta atgatctctt aactactagc ctgaaaagtt ttggatagct 321240 tataatctat caggcataaa ggattcatct tcttgggata aatcacatca taggtaacga 321300 acttaaacaa aattctaact tctctttgga aattgtatga cctttctgag ctaaaacaaa 321360 gtagataggt agaataagtc ttagaacttg ctttgtcttt agaacacagt cactggtcat 321420 tcatattatc tattgataag agtggaatca cagaaattta gggtccttga aatcgttgtg 321480 aaaagtagga aggtatctaa gtaaatccag gggatatagt acaagtatgc tgttgatttt 321540 gcctagggtg taccaacaag tatagagtat tttaatacaa aggcactata acaaaaaagt 321600 agaacacaaa tctgccacta taagatatgc agcctcaagg actcagtgga aataagatgg 321660 tatttgggtg gggtatgata aacagcgatt attctattta tggttctgaa gtcctgaaaa 321720 aatctgctat ctctgccact gggtttttga gcatggagtg taaaagaatt ataagggctg 321780 ttacaaagtt tttagctatt attttagtcc tttagtcctt tttaatctct tggttttaga 321840 agagattgtg caagttgggt agcagttaag gtggataaat ctgagtctta accgggttta 321900 tccataagaa tgtcaagcac ttccttgaga tcttcaattt tggcttgatt tagattcaat 321960 agtagtcgtg aatcaatgtc cagattatct atggtttctt tatgagtgag ggagtcagag 322020 actcaaggtc tagaccatcc agatagcatt taatttacag ttccacccac gtagtaactt 322080 cctacctatc atgtgagtga atatggtatt acagagaaag aaagagtgta atttagttaa 322140 agtccaaggg tggctgtaat gggctgggat gtgaggaata tttgataatt attgcagaaa 322200 cctaccatgt gagtagttta ttttcaatga agaggttgtg taatagtgat aaggtttaag 322260 gttgatgata tttagcaccc atatcagtta aaaaaatttg cagagttgtc atttaatatt 322320 tagagaaagt tttctttttg acttgaaaga tgaaatgttt tgtgcttgat acccaccgga 322380 agcaccttga tttgtcactt atttcatgtt ttgccctttg attctgagct aatgcaaaac 322440 aagtgttttc caatttcctt actgcttaca ggcgtcttta tcaagagact tccttattcc 322500 gggtttaatg tctgggatag gaggatgtaa ttttatctct actttgattt tttttaatga 322560 aactctttca aaatgtttag tgaggtgcta gagatctgat aatgggaata atattgctca 322620 ttgtagtttt tttttacata ttaaatcctg tttttttggc ttcagttcct ttctgcaaaa 322680 tggggaaaga tgtgtgtggg ctcatatctg cttcaaggtc tactgagtcc ttcctaaggg 322740 tattaaagag cctatcttca atttctccaa tggacacatc ctttctttgc ttgcaggact 322800 ggattataaa acaatctatt ttcacaggga agactttagg ggtagtctcc aaaagacctt 322860 gtccaatatc ttcagttttt ctaaaattct ttgtttcctg taaaatttga aactctttgg 322920 tttcctgtgg tcttttatgt caccactgag actgacccat tttgcctttt tcatgtactt 322980 ttttgcatct agggttatca ctaaaatatg aactccttgg tatagatttg ggagccctgg 323040 attctaactt cctaaagatg ttttataatc ctcgcaagtt ttcctctatt ctgcctgtgc 323100 tttgaagagc ctttgacggg gtctctcatc tcagagttag atggcttaaa atcaaccaca 323160 gatgtttccc tgttgtgagg gtagtttaac atgaagaggt cattgagctt tggggttttc 323220 tggctgtctg aaagagaaga aaaattgttc agagggagag atgggggaga gaataataat 323280 aggataaagt ctatttggtt tgagttatga tttgttggta tctaaaacag agagagagtt 323340 ttttttttct tttgccctgg ctaacaaatt tcataagaaa gcagttttga aatctgaatt 323400 gcctttggat gtttctcaga ttaattaaaa atgtagacta ctggatgttt gaaattttga 323460 tctattttta ttttaatgta ctcttaaaaa attttgttca tagaaaaact tcccccaaag 323520 tggctgctat aattgtaact catctctgtt gaaattatgc catttaaata agtatatgaa 323580 tgtggattat cttataaaca tatggaagaa gaagtccaga gggcgtttgg aattagaatg 323640 agactggagg cataccctga aagtgtggta aaactctgaa aaaaatgttg cttatgaccc 323700 cttgggtctc tcaacctgat ttctacattg tctaactgta gacctgaagg aatttgcagt 323760 ttcttggggg tacataagat gttaataggg gatttctctt agaaccagac tgatgatcaa 323820 gacaagattg aggaaaattg tcataggttt tgataaggac ctagggaaaa atttctccaa 323880 aggacagcag gctgagaaga aatcttacaa acttctccat ccctggggct gtcttgaggg 323940 atccacttac ctgggtctct ctcactctct tccctatgaa cattccttat atatacacat 324000 gaagtggcaa agacaaaggc gaagagtagc atcactagta ataaggcagt ttcaccaaag 324060 ataaattttt ttcaagtctg atcaaagtgt tcctgaaaag agttccttac ccttaggaga 324120 caaaataatc tcagtatact gggagttcaa tgaaaatata ctggggctca gtccaatttg 324180 atttacttaa tacactgttg cactaagaga tagtcctgac caggaagcta aaaggatatc 324240 tgaggaggac aatgaattaa ggttctgaat taaggttctt gtgcctaggc tgcaaagagg 324300 tctcaatctt tatggatctt ggtgagatct ccaagattgt tcaatactga attcctagaa 324360 atacaacctg aagaatattt tgataaggca aagctgagtt tattcttaat gtggtaagag 324420 aaagcaatcc cctaatagat attaataaca ttttggacaa ggaaggacaa agttagaata 324480 tttatgagac tttaaaggct catttaagat gggtctttaa atgccagggc ttgattagga 324540 tttggcgagg attatgataa aagagtttac tgttggtgga cacagcaaag taaagatttg 324600 gaggtgaggg attcaaaaac tcttagaata taagctattg tctgatgttt tctactgatg 324660 agttaataag tttctaagga agttcttgta ataaataata aacattattc acaactttta 324720 tttttctgag caagaattta ctggaatagt aaagtgaaaa tagtgccagt gaaaatagtg 324780 gaaaatttaa attggaggca attagccatg agagtgtaca tgattttgtt tctcacagtg 324840 tcagttaaca tttcccctct gtgcaaatcc ttcaatagtt tacaatttgt ttataataaa 324900 tgtccgtaga atggcccaca aaactggacc tggtcaagcc actttctgtc acctcttacc 324960 tcttagctac tacttgctgt tctggaacca ctgggccagc ttctgcacca gattctctct 325020 tggccccaag catttttcca ccgtctctct ctctctgctt actcctctgc catcatcagt 325080 tgtcaactag gctaacctgg tacacttctc taagtatcaa tatcactaca atgttgctct 325140 ttaccccttt ccactatttt caacactgat catgtaatat aaaatattat ttaatatttt 325200 aaatgattat ccatctcctt gcactagaat gtaaacatgc tgactgtaga gatttttgtc 325260 tttgtctttt actgctccaa caccaattct ctgactttga aggcaataaa aactgacttt 325320 aaacctgaaa agaaagagct aaattgcctt ccagttcttt gaagtaaaag tttatacttc 325380 aaaagaattg ctctggaaag ggagaaactg caagagaaat ttcaacttct tgcttctcaa 325440 agagaaaggc aaaattatat aaaattttga ggaagggtgg catttaggtt aaatttataa 325500 taaacagtat agctgggtta gatggaagca aatggagttg gtcagatggg gttgatttga 325560 tcaaagccaa gtggaaatga ttggaaggat tagagagcag accagtacaa gcagtgcttg 325620 ctgatgtgga catttaagtg aaaactcatt ttgaccaatt ttgcagcttc ctgagtatgg 325680 ggtgaggata tcctgttctt taggggataa taagattttc agcttctttt gtacatgtga 325740 tgatgccttt aggcaagggt gatatttttc attctcatga ccaaagcaca gaccataagt 325800 ctgaacacag aacactatac atggtaatct aggtactcta tttgcctttg taggtgattg 325860 caattttttc cttatttaaa attttaagac cataaagaat acttgaaaag taacttttta 325920 ccaatcattt aaaaaatact gattaaatga taaaatccct taaaaacaca gttaatgcaa 325980 aagccacaaa aagaaatata aaatatagct ttacatctgt taaagacact gaacacataa 326040 ttaaaatatt cccaaacaac aatgctccat gctgaaatgt tccactagta aatttttaca 326100 aatatttaag ggaaaaatgt ataattttca ttttctcagg atagctgact tctagtaact 326160 aaacatgaca aagaactata aaaattgaat ttacagaaca tggctactag gaatatagat 326220 ccaagtagcc tgaacacaat aatagtaaat caaattatgt gaattttttt ttttttgaga 326280 tggagtcttg ctctcttgcc catgttggag tgcagtggca cgatctctgc tcactacaac 326340 cttacaacct ccacatccca ggttcaagtg atcctcctgc ctcagcccca ctagtagctg 326400 ggattacagg cacttgccac catgccagtt taatttttgt atttttagta gagacagggt 326460 tttgccatgc tggccaggct ggtcttgaac tcccgacctc aggtgatcca cctgcctcgg 326520 cctcccaaag tgctgggatt ataggcatga gccaccgcac ccagccaaaa tattttttta 326580 aaaggtcact gcattataat catttggggt ttacttgaga aatgaagatt ttttttttaa 326640 acattcaaaa aatcattcaa cacttctggt ttcagctctg atatgtgagg aacttgtaag 326700 ttataattac tgtccttata acaagataaa gcagaacaaa ttgaaaaaaa aatcaattat 326760 ttcctttaac ccatcagaga actgaggctt cagggaaagt tgccacccca aagtctgggg 326820 acaccgattg atacacagct gaaatttgct tagctggaac agaagccact ggagccacaa 326880 attgatagga acatttaaat agcaatttag atgaatagct gggctgaatg tgggctagag 326940 tgaaaggaag aaactcctgg gaacccccac atttttgtgg gttctacctc cagaacctca 327000 acaatttctc atggtaaaga tttaagaaag atcccctcct cctttggaaa gggagagaag 327060 agtaatcatt gtgaaataca cccagagcat tcttcataac aaagacctaa cctccagggg 327120 aaaaatttta tctgagccat atctcagtaa gggataaggg gaagggcatt cctttcattt 327180 cagccttctc tagctttcct gttttaccaa tcaggaaata aaaaacccac aattgtcaat 327240 agagatcagc acttcaagga aatagattgg aagcaaaaga aggagggaaa agagtagaga 327300 ggtcaggtgg agttgaggga gaggttctgc cactgaagga atgtttgtga tggttgtaac 327360 accaagacac aggcacacag agacttattc aaaagatcat agaacactct cccctatgtc 327420 ttacgacccc accagcagtg ttctgtgtaa tagtagatta cagttgaaat agctgtaaga 327480 caccaattct ctcagaggag tacttaggga agtccaaagt caagagcaga aacaaaagac 327540 actagaggaa tttggcattt ctggtgcctc tagtaacagc aaacattaaa caaagcccaa 327600 ttcctcatca gatttctgta aatagcattc taaagctcca tttacctcag tacttactac 327660 cagatacagt tcaacaaaaa attacaatgc acatcctatg acaagaaaaa acagtctgaa 327720 gagagaaagc aattagcaga accagactca gaacaaagat gttggaatta ataatagaga 327780 tttaaaataa ctatgattaa tatgttaagg actcttagac atgcaaaaat agattatata 327840 agcagagaga tggaaactca aaagaagcaa gaggaaatgc tagaaataaa aaacactata 327900 acataaatga agaatgcctt caacaggctc gtaagtagat tcagcacagc cgaggaaaga 327960 ttcagtgatc ttgaagttag gtcaatagaa attttgcaaa ctaaaatgca aatacagaaa 328020 aagaaaagaa tgaagaaaat gggacagaac atccaagaac tgtggaacaa tttttaaagg 328080 tgcaacatag atgtaatggg gatactaaaa gaatggagta tagagcataa tatatgtttg 328140 aagtaaaaat ggccaagaat ttttcaaaat taataacaga caccaaacca caggcccaga 328200 aatctcagag aacacaaaac agtaaaaatg caaaaaaagc aaaaacaaaa acaataaaac 328260 ctacaaatat catattcaac ctgcggaaag acaaacacag aaaaagaaat ctttaaagaa 328320 ggtagataaa acatcctcgt cttctcatca ggaaaaaaaa tccgaaagta gtaatgtggt 328380 agtcaattat ggcatatgga tgtgtgaaaa caatggcagc aatgccacca gagataggaa 328440 aaaaaatgga aatcctctgt tataaggcac ctgcactaag cgtgaagtgg tatggtgtaa 328500 tttgaagatg ggtttagatt agttaaaaat gtatattgta gccagggtga catagcaaaa 328560 cccagtctta actaacaata caaaaattag ccaggtgtgg tggcacacat ctgtagttcc 328620 agctacttgg gaggctgagg tgggaaagtt gcttgagccc gggaggcaga ggttgcagtg 328680 agccgagatt gcacccctgt actccagcct gggtgataca gcaagaccct gtctcaaaac 328740 aaacaaacaa acagaaatgt atattgtaag ttctagctca accagttaaa caaataagaa 328800 aagataattg atatgctaag aaaggagata aaatggaatc atgtaacatg atcaagtaaa 328860 agtagagaac acagtaaaat agaggtctta aagaaatagt aatgcaatga ctagaaagca 328920 gttgcaaaca tggaatatat tgatccaact gtataaataa tcacttcaga tgtgaattat 328980 ctacattgaa aaacagaaac tctcagaatg gactaagaca agaccaaact aaatggctac 329040 aagaagccta ctttaaaatt aaagatttgg atactctgaa agtaaaggga tggagaaaga 329100 tataacatgc ttacagtaat caaaagacag ctggagtagc tatattgatt ttcagacaca 329160 gcagaattca gaacaaggaa ggttaccagg catgaaaagt ggcaatacat agtgagaaag 329220 ggccaattct acaagaatat ctaaacgtgt atgcacctat taacagtgtc aagatataca 329280 tgaggtaaaa gttgataaaa ctgaaaaaag aaatagataa accctattta tagtcagagg 329340 ttccaacatc cctctggcat agacataaat aagaatattg ataacctgaa cagcattatc 329400 agttaagttg tttgatgttt atagagtact ccaacaacag aagaatttac atgaatatac 329460 attattccaa agtttacatg aaatattcat gaaaacatca tattatgtgc cataaaacaa 329520 atttaaaaga ttataaatca tactaagtac tcaggtcaca atgtaataaa actagaaacc 329580 aataaagaaa gacatagctg ggaaatctcc aaatatttgg aaactaaaca acaaacttgt 329640 atataataga cacatcaaag aacaagtcat tagagaaatt aaaaattatt ttgaactaat 329700 tccagctgga caatactggt tacaatttgt gggatgcagc taaagtagtg cttgcaagga 329760 aatttttagc attaaataca ttaaaaagaa aaagaccaat aatcaatctg accttccacc 329820 ttagaaaaat acagaacagt ttaagcaaac agaagaacct taagcaaaca gaagacaaga 329880 aataataaaa gaataaaaat caatgaaatt taaaacagaa aaacagtatg gaaaaccaag 329940 aaaaccaaaa gttgatttgt ttaaaagatt ggtaacattg ctaaacttct agtcaggcta 330000 agcaaagaaa agaaaaaaga caaatgacca atatcaggag taaaggaggg gacatcagta 330060 ttgatcccat ggacgtgaaa aggataacag aatactaaga acaactctat gcctccagat 330120 ttgataaatg aaatggacca ataccttgaa gtaaactacc acaacctcca aaaggaaaaa 330180 taggtaacct gaatagcaat atatctatta atgaaattga aataataatt aaccttcccc 330240 caaaatagca ccatgcccag agagttttac tagtgatttt tactaaacat ttaaggaaga 330300 tgcaatacca gttctccacc attacttcca gaaaatagaa acagagggaa gacttcccaa 330360 ctcattacat cacaccatca ttaccctaac ataataacca gataaaaaca ttaaaagaaa 330420 gaaaaactac agaccaatat ctctcatgaa gattgacgta aaactccttg acaaaatatt 330480 atcaaatcga attcaacaat gtatagaaaa aattagtacc attatgtaca ttatgggatt 330540 tattccaggt atgcaaggct ctttgaacat tcaaaattca gccaatgtag tagaccgtat 330600 caatagccta cagaagaaaa attatattat tatatcaata gatgcagtaa aagcatttca 330660 caaaattgaa tattcatgat ttttaaaatc tcagcaatct aggaatacaa ggaaatttcc 330720 tcaacttgat gaaaaaattc tacaaaaaac cccatagcta atatcatact gaaatgtaag 330780 agactgtatg ttaatttcag gagcaaggcg aggatgtcct ccaattctat gcaacatcat 330840 actggaagtc ttagctagtg caacaagaca agaaaaggga atgaggcata cagattgtga 330900 tggaagaaat aaaacagtct ttactcaagg atgacatgga gaaaatccca aagaatccac 330960 aaaagaaaaa cttggagcta ataagtgagt ataacaaagt taaaggatat aaggttgata 331020 tacaaaaacc aattgcttac ctataaacca gtaatagtct attgaaatta gaaaaaaact 331080 ataatagcac cataacaaaa gcaaataaaa cccttactta taaacctaaa gaaaaacagg 331140 ttcaggatct atatgtctat atgtagaaga ctataaaact ttgataagag aaatcaaaga 331200 agatcaaaat aaatgaacag atatatcctg tatccataga tagaagactc aatattataa 331260 aaatgtcagt tcttcctaac tttatagact caattcaatt ctattcaaaa tcccagcagg 331320 ctattttgta gatgttgaca aagaataacc aacataacac tgaagaagca caaagacaga 331380 ggagaaatac tacctgattt taagactttt actagaagct gcagtaatca agactttgtg 331440 gtactggcaa aagaacagat acataagtta atagtacaga atagagagcc cagaaataga 331500 caccacacaa atataattaa ctgacctgtg tcagggaaca aagacaatcc aatgcataaa 331560 agaatagtct tttcagttaa tggtgctgca acaaggagat gtctgtatgt gaaaaagtga 331620 acctagacat aggttttaga tatttcacaa aaattaactc aaaatagacc atagaactaa 331680 atatgaaatg caaagtgtta ataattctaa aagaatacaa gagaaaatgt atttgatctt 331740 gggttttgtg atggggaaca ccaaagacac agaccatgaa gggaaaaaaa tggtaagctt 331800 ttaaaatata agttctgttt ggaaaaaggc acttaattaa aagataagcc acagattggg 331860 ggaaaatatt ttcaaagtac atatctaata aaggtattct agtcaactgt atagagaact 331920 cttaaaactc agcaataaga aaacaaatga ccaattaaaa aataggcaaa agatctgaac 331980 agacaccata ccaaaaaaca aaaacaaata caaatgataa atacacttat gtaaagatgc 332040 ttaacatttt ctgtcactgg agataaaaaa taataaaata ccactacaca tgtactcata 332100 tacatgtaca cagtacacat atacactaca cacagtacac atgtattccc atgtaataga 332160 atggctaaaa tccatccaaa gcctgatcat gccaacttct gttgaaaagg caagcaacat 332220 taattggtga tggaaatgca aaatagcaca gccacttttg aagacagttt ggcagtttct 332280 tagaaagcta aatgttgtcc tgccatatat ctagccacta cgctccttgg tatttaccca 332340 actaatctga aaacttacgt ccacataaat gccagcacat gaatattaca gctttattca 332400 taatgaccaa aacctgaaat taactaaaat atcattcaat aggtggatgg ataaactgtg 332460 atacatttat acaatagaat actatcaagc aataaaaagg attaacccat caagccacac 332520 aaaaacatgg ataaatcata gatgcatatt gctgagtaaa agaagccaat ctgaaaagaa 332580 tacatacaat attcttcatt tttgtaacat tctgggcaag gcaaaactat agatatcaat 332640 ggttggcagg gttcaggcga aggggcaggg atttaataga taaatcacag caaatctatt 332700 ctgtatggta ctgtaatagt gtatacatta tactgtgcgt ttgtcaaaac acagtgaact 332760 ttaaagcaca aatgaacctt aatgtacaca aattttaaaa aatcatttag gagtttgggg 332820 gatccaagat ggaacacagt gtctgacaaa agaatccagg tgttttacaa atgtattaga 332880 caagcttacg aataatgttg gggagaaaag ataatgactt aagtaacttt gaaaatgagt 332940 ggaatctgtt aagactagag gcaaagtgac tgtacaggag cactgcacac tatttgataa 333000 agttgttttc tgtaggtgta tgagttagca attctaaatc atgatacata tgtatattgg 333060 aattgaacaa ttaagtaaat ggttggcaga tggtgtacat tttcttattg ttggaatgaa 333120 aagttacaga caagaagaaa agaatgattt gtgttgtaat ggattagagt tggaaacgtc 333180 agtgtaaact tatgtttagt ttaatatgca gacagatggt tacacataga aatatagatg 333240 catgtattta catagttatt gtacacaccc tgtgtcaact gagaatgctt agaagcaatg 333300 acactctagt aacaatgggc acacctagaa cccagccctt agtttctaat accattctcc 333360 aatagaacaa atcagggatc cttgtagaaa tggctgattc taagactggt taggaaatgt 333420 acaagatgag cctggagcat catatagtgc cagagagtaa ggaagtacta aaacaagaac 333480 cccacattga tgaaagtata tcaaagggac tcaggaacca accaaaagag cttccagtgg 333540 tcaaatctgg aacaaatttt taaaaataaa tagcataata ttagattaca acccaaagta 333600 taaaatatcc atgaatccat attgatgtaa ataatcaaat gaataaataa actggggaga 333660 acatagattt tttgtgcaga ataatttcat atagttttta tagatacttt tgcccttaag 333720 gaggttgaac tccttactcg tcaagtgtgg gaagaaagtc attaggcaca ttggtgactt 333780 tctttcaaag agtacagggt ggaaatgggg gatggaaggg aagagtaact gtgcagggga 333840 gaaacctgac aagcactatc tctacatggt aatcaaggtt aacatcagta gtgataaatc 333900 atgctgatag tatatacctt tgatatgacg tgataaaaat tgcactttac ctctacagtc 333960 ttcctcccaa aaacccataa gatcagtatc attatgagaa aaatcatcaa acaaatccca 334020 catgagatat actctacaaa atacttgact agttttgctc aaaactgtga aggtcctcaa 334080 aaaggaaagc ttgagaaagt gtgacagtca agaagagcct aaatagacaa gacaactaaa 334140 tggaatatgg catcctatat gggatcctag aagagtaata gtacattatg taaaactatg 334200 gaaatctgaa taaagtgggc tttagttaat aataatctat caatattggt tcgttgagtg 334260 tgacaaatgt gccatattaa tacaagatgt taacaggagg ggaaactggg tatagggtat 334320 ttgggaactc tgtttcagct tcacttttta aaaaatcttc aaatgtttac ttcaaaaatg 334380 aattcaaaat cactcaatgt aaatcactat ggtaacataa gagagaagaa aagttatatg 334440 atcatctcaa aagagaaaaa gcatttgata aaatataaaa actattcttt ataaatctct 334500 ttattggaac tacgaattta tgggaactaa aaattgaaaa aaatttaatg agataaaggg 334560 tatttacaaa ataaattaat tgtaaaatta ttgacagtgg agatagagaa agctttttta 334620 tgagattggg aataaaagag gatttttttt catcatttct attcattact atactggatg 334680 tcctaactag gggagtagag tcatagaata aggattggaa atggaaaggt ataagtttca 334740 ttatttactg acaagaaaca agtctgaaca tgatcaatta aaattaggaa gttaattgag 334800 caagattgct gggttaaaaa gcagataact aaaatgtatt tctatgtaaa atgacaaatg 334860 aaaaatgaag tttttaaaag ataacatttt tgggaacatc agaaacatca attccatagg 334920 aaaaaattca cacaaaatat tatgaaacat tatggaaagg aagcaagtaa taccttacaa 334980 atggagggat ataatatatt cacagtggca aattcaatta catatactat acatgttaat 335040 tctcccccaa attcacttaa agatcccaac gtaagagcat tctaaatctg aatgccattt 335100 attaaatgtt caatctaatt tcaagaatta tatatgacac aaaaagtcaa gaagagccaa 335160 gatagtcttg atgaagatga caattttgca tgagttacat ggccaaaatt taaggcctac 335220 tattgcaagg ttacagttac tgacaaaaga cagaaaacta gcctaatgga gcaaaataga 335280 gactccactc cacaagcaga tcaatagata tatgattact tgctttatga taaaagtgcc 335340 actcctgcat gatgaggaaa gaatggtttg ttcaatagtt agtgctggat atcaatacat 335400 aaaaaagtga attccttttc aaaccataca gatccatcat ttctaggtgt aatgttggtc 335460 tattcatgaa aggcaaaaca gtaaagcttc ttgagcatag cataacatag gagggtgtca 335520 tcataatttg gcagaaagtg aaaaatacca ataacactaa gcataaagga aaatattgat 335580 gaattagtct gcatccaaat taaaattttt atttctcaaa gtatataatc agtgaagaag 335640 catcgtataa aagatacaac ttgtacatgt caaaaagtta gaaaacactt aaatgggtac 335700 ttcacaaaag aggatatctg aatggccaat aagcctatga aaaggtattc aaggtcatta 335760 gccatgagaa aaataattca gacaacaatc agataaacat cttccagtat atctagacag 335820 tccccaattt ataatggttt gatttatgat ttttccactt tatgatgttg tgaaagtggt 335880 atgcattcag tagaaaccat accttggatt ttgaattttc atttcccggg ctagccactg 335940 gcagtatgat actctagtga ggctaggcag cagcagtgag ccatagctcc tagcagtcat 336000 gcagttatga aggtaaacaa ccaatacttc atcgcgtact gtgctgccac cattttgacc 336060 cactgtaggc taatgtaagt gttctgagca catttaaggt aggctaggca aagctatgat 336120 gttcagtaca ttaggtgtac taaaagcatt ttttatttac agtgttttta acttatagta 336180 ggtttattag gaggtaactc cttcataaat caaggatcat ctgtttaaaa tttgaaagtg 336240 tgtgtttttt agaattctct tagtattcac tgaagttgaa tggaggcaac atactctcag 336300 gtatatggtt aacaaaaatt catgcatgat tgacccaaaa tatgtataca tgaatgctta 336360 tcatggtgcc atatctaata gcaaaaattg aaaacaaagt gcccaggagg agttgaagga 336420 taagtaaacc ttaaaatatg cacatattct ctcaaggaac gtggatagta ttgtgactga 336480 ttcttctcca tgtgtgatcc acatagatga taagatcatc atgagaagaa cttaatttta 336540 tacttgagct ttgctttgac tgaaagatga gaaattttgt gattattggt atcatctcta 336600 tgatgtcata ttacctagat tcacatattc ttaactccat taaaatagaa attatatttg 336660 tgggcgggga acttattttc atccatctct gtttccttcc aattgagcaa ttccttattt 336720 tatgttaacc tgattttagt ggttcattgc cataattctt agaaattata tctcattttt 336780 tcctgtgatt ttactgtatt gaagtaaatc tggttggcag gatatacaat attacatgaa 336840 tgaaatttgc ctttggtaac tgagaaagtt caaatagacc ttggttctag cgaagacttg 336900 tttctaagga atttagattc attctttcag acagtatgaa tatcattatg gggtcttctt 336960 catgagttat gtatgtgatg ggattcttgt aagattttca ccttttacct gagcttgcct 337020 tgactgaaag ttgagaaaat tttgtgattc attggtataa tttctacagt gcaatattta 337080 tttggatcta agcatgcaag taaaaaaatt catccctgtt atagtatttc aggtttgcag 337140 tacgttatga catttgtaga tcattgatgg actatgaata ttcaagggac ctggcaattg 337200 tacccagggg attgagatcc agatacttgt ttgtttgccc atagatataa aattaggagc 337260 ttcctgatat ctaatttact tttttaggaa taacacccat gagatacagt tctcatctac 337320 tgccctactc ctgtccttag ataaataaca ccggaagaag aagactctct ggcctcttac 337380 atcagggaca catgaaaagc cacactgaat atgtatgaac tccaatatac tttcacagaa 337440 gggtttaagg atgccatccc tggttataat ttttaggacc aaatatatat atatatacac 337500 acatacacac acatttagga tagatatata tttaggatat ataggataaa tatatatatt 337560 tagtgccatg gtttgggtca tgaggaggtt tgatgacata aaaattatgc tcataagtat 337620 tatgctgaga cccattcttg ggaggagatg tgggggtgtc ctaggctgtg caaaacatag 337680 ctatggaaac agaagttatt aagagaaaag aacaagcagt cagtgagaat ttagataaga 337740 gactgtaata gaataaaagt atcagattag tgaatggttg tcctagtaat ttggaagaaa 337800 aggaataaaa aatggagtca gactactaaa tggcaaaaat aaagacttga agaacttaat 337860 tttatacctg agctttgctt tgattgaaag ttgagaaatc ttgtgatttg tcggtatcat 337920 catctcaaat caacttattt ttcatctcaa catgaagaat atcagctcta gccttttgga 337980 atttcagcaa ctcagatgct tgttagaact tatccaggac tgcttgcagg acccaaaata 338040 ctaataatcc atatgccttt ttttccagct gaaattagct gtcttaagag ttgtttttca 338100 gtgctctgag gatatccaca aatatatccc aaggcactct gaagtgtgtt ttcaatcttt 338160 ggccctgcac actggggatg cccactggat gttgcatgga gtgttgcctc cagttgactt 338220 tgatagacac aataaacacc acgtgagagc cccctcatga aggagggctg aggacttgga 338280 gtccaattct ccacctcccc tgacagatag gctattcaat gccttgggaa tccgacatga 338340 aggactgctt atagcagtcc ttgaaaactt tctacagaat gtgaactggg agaagctaaa 338400 tgctgtactc acaagctggg tgacttctcc attgattttt accatagctc actgaaacat 338460 tttctaaatt aacaggtata aattcacaga cagatcagaa tagatccttg gtcctttcca 338520 tttttctggc acttttgttg ccaggaattc aaatacaact aagagaaaaa gtgggtagct 338580 agcaagaaca gatagtttct caaatattag tggcagtaac ccaactttga gaaaatatgg 338640 agaaagagaa gaaaaaaccc ttaagactgc agtgttagct gcccagttac aattattcac 338700 aaagtgagca aatacttatt tgggccacca ataaataaga gggcacaagc taacgggaaa 338760 ttaatacgtc actcatgtaa aaagtcaaca cattagaaaa aggaatcttg gatgagattg 338820 agaaagatgc aagggataaa acctgacaag ctttacaacc tccttgagga ggtcttccct 338880 actctgtaaa atcagacaga aaatcattgg caaatggagc aaagcatggg caaaactgat 338940 ataatgagga aacagagctg ggaaaggata aatttatgtg tctgtttctg tttcctatct 339000 tttaatcctt ttttaccctt tcttctggat actggagcaa cgtattctgc aatttctaca 339060 ggccttttct gttttatcct aaactaggaa aatatccaga tataagtatt tctggactat 339120 ctgctacctc ttctttctcc tctgaggttt tcatgcaaat aggcgaggtc ctatttgcat 339180 aaaataggaa gaatatgcct tgtctcctaa tatgcccaat aatcttttaa gaaagggcct 339240 gctgtgtaaa ccaagggcta tgatcttctg tactctgaag agagtgcttt tggagcttct 339300 gggatgcaag gtatctacat tgctaaatat gtgctttctg aaacaaaaga tggctgtggg 339360 agagtaggag tctcactcaa tgctggagaa gcactcccaa gttacagaaa ataaacccat 339420 atctatgagt cctaggaaca aatgataaag atttaacaaa agagatcaat accattgttg 339480 taacttacaa cagagaaaaa ccttggccat gtatagaaca ttttctctat ttttacctca 339540 aatatgatgt aattagaaaa attttaaaaa acgtggcata gttaaaaaaa aatggcacat 339600 tcacttcata atgcttccat attgcctgtg ggaaagttag gaaaacttga cagggaaggt 339660 caaactgttt atagatttat gcatgatctt agagaaacaa gttgtgattc ctctgacact 339720 tgtaattccc agccttgcca ctgttttaat atctgttcct gagttatcta agtatttttc 339780 tgtcatggat ttatgttcaa tgttttgttc tccatgttta gctggggagt cgaggttcct 339840 gtttgagttt acctgtggag cgggaggctt tcaatatttg tggcaacgga tcttcctgga 339900 attcagagag tcacctactc cattctctgg gcatttataa gaaaatataa agaatattcc 339960 tcacattagg attccatact aattgttatt gatagctgct aataacttac atgctagtaa 340020 agaagacatt ttagctttac taaatttctt agactcccag gacgtaaaac ctcgctagct 340080 aagttgcaat attaccaact gaagtaaaat atttgggatc tgtgttattg gcagatggaa 340140 ggtggttgca tcttgaagtc agcctaatat acaaatgaaa caacatgcca aaaaaaaact 340200 tcaccgattt tgaggattaa ttgtagatct ttgcgtttta tgaaaaggct aagcctctca 340260 ctgagatgtt acatgaaaca tcactagaac tctttattaa agtcaaaata aggctgaaga 340320 agtcttttat gcccttaaaa tagctgctat ttcttcactt gtattacttt tttaaccttg 340380 ttaaaaaagg agttctacct tttctgtctt gagattaagg gttactccaa aattaggcct 340440 tgattatagg cacattgctt actttcccag gttcttgtat tttgtctctc tggaaatgcg 340500 atgatattta taaggtacag tggcaaccac tcccctgatt aaaaaggctc attcagtcct 340560 tgactctgag aaatttaact tacttacagg tacttcatgt tgttactgct attttacaag 340620 ttcataagac acaacacttg tcagtatgct gtcaaacgag ctaagaacaa gtcttattgt 340680 gtgatcctaa tgctattcta ggaaggtgta accttttgac agctattctg tggccagatc 340740 ttgacagaat aagttgaact tgactgtctc agagtgattg aggaagacac tggagcatgg 340800 tctaattttt gtaatattcc tattcccaat gttgactgaa tattcatgaa tatattctgt 340860 gtgaaagacc cacaaaggaa tataaaagca tgttctacgg taatcaaccc tcatgaagct 340920 tagaggcttc tgtttttcga aacataaaat cagcccaagt ggcagaattg tagttattat 340980 accagctgtt aaattagcca ccagttataa agcagatatc tatactggta ataactatat 341040 gtttgtggtc tgttatgtga ctagccaact ttggaagaat agatgctaac gtcaatagga 341100 actaaaatat tacatgagaa gctaatttct gatttagtag agtcattcaa acttctctaa 341160 cagatttatg taatttattg tagagctcac agtggaaaac aagattaact ctttaaaaag 341220 aaattaattt gcagacctag ctgtgaaggg cttctgacgt ttagactggg gaaatcaaac 341280 ctctatcact tctgtccaaa acctcctatt cataatttca gaaatagcca actctcttaa 341340 gaattagaaa attaggaatg aaggagaact aagatgaaca ccataggaaa atgagaatta 341400 cataatgaaa tctttccttt attccgattg ttatatgatt gagtggcttt ttcatgccac 341460 caacaagttc gttcaagcaa aaggaatatg ctgacaactt gaaatctttg taatagcatc 341520 atataattca ggaaataata tgaagatatg ctctttgtca gaaaaattct ttccttacct 341580 aaaataagtc aagaaagcct actaaggccc atgataccta ggatctgctg gcacaagaac 341640 tttatagaac ttccaccttt agaagatagt aaatattttt accagtgttg tgtattggtg 341700 tctggatagg ctaaagcaga tgctcaaaca gtgatcaagc tcttactgaa tcatatcatc 341760 tcaaccactg gaattcctga atatctggaa ttcagtaggg gaatcattct gtatttgtgg 341820 gaattcggga attttgtaat actctacaaa taccaataat ttacctacct gttatcccca 341880 gtcttctgaa caagtggaat gagtgaacca cataccctaa agaattattt agctgaatta 341940 tttagctaag ttatgtaaaa ccttaccatc cgtttcattt aaaataagat taaatccctc 342000 tagcaagccc aacattactc cctttgagtt tggaaggtct actaatcttg ggcttaagcc 342060 taaccctttc tctgatacaa tggaaaatcc tcatgaccat atatgatact taaagagttt 342120 gtgggtttcc ctaggctcac cttgccaaca tgtggccaga tgctgaaaaa gccgcctggg 342180 gaagtgtgtc attgatattg aacaggagat tcagtctata tcaaagtgtt ctgatgacag 342240 actgtgacca cactggacag aaccctatca agtgtggttg agaattcata gtgctatcaa 342300 gatgaaggag aaacccaagt ggatacacgc ttcacatgtg agaccaacat ccaccatcga 342360 gtggggtata attcccattt aggaccttaa ggataaattc tctagatagt aaccttgaat 342420 aatatgcaag ctaaagagaa aaacttattt gatagacagc aggagagata gactgttttg 342480 ttattaatac gttcttctta attattttga ccattataat tttgatactt agtttgtatt 342540 aattttgata cttagtttgt atcaattgaa cataaagctt attattagtc tttcttttaa 342600 aagttagtat ctcaacctca aggaattttg tggtaattaa aaattgtcct gaatatgaga 342660 tcaggactta agaaacccct ttctttgtca taatacttca aactcaccaa ctggatgatt 342720 taaattcaga agacatgaaa aatttcaaat cttcccactg attagtcaat attacaaaaa 342780 tcttaaatat catcaccctt tgtgttattg aagatactga tgagaagaaa tttttaacta 342840 attaagttga acgtaattat attcaaattg aaagtccctg aagggtatca caaaactcca 342900 acaactctgt atcttttttt tttttgagca gagtttcacc ttattgccca ggctagagtg 342960 caatggcacg atcttggctc accacaacct ctgcctccca ggttcaagcg attctcctgc 343020 ctcagcctcc tgagtagctg ggattataga catgcaccac catgcctggc taattttgta 343080 ttttttgtag agatggggtt tctccatgtt ggtcaggatg gtctcaaact tccaacctca 343140 ggtgatccac ccgcctttga ctcccaaagt gctgggatta caggtgtaag ccaccacgcc 343200 cggcccaact ctagatctta aatagccatg ggggtccaat ttaataaagc ttaaatagac 343260 acacagatga gaaaatatcc cagcccaaat ggtgagggtt agtttcttca aaacccccaa 343320 aacgtatcat cacctaaaaa tgagcttacc ctgtttagaa cctggcagtc tccagtcccc 343380 atacttacaa actcgaggat aattaaatgg tctgtatcat ttaatattac aatagctaat 343440 gtgagtaaac tgaattctac ttgtacatga taggctttac cactatgaaa tgtttttaca 343500 cagggactaa aatggcacta tgatcaaact gaaagagatt tcttttttta atagatgggg 343560 tctggctttg ttgcctacac tggagtgcag tagcacaatc atagctgtct atcgcctgta 343620 actcctgggc tcaagggctt cctccgtctc agcttcctga gtagctggga ctacagggac 343680 atgccaccat gcctgcctat ttttttttgt agagtcaggg tcttgctcag gctggtttcg 343740 aacttctggc ctcaagtgat cctgctgcct cggccttccg aagcactggg ttcgcagaca 343800 taagccacca tacctggcca gagattatta aatacagtat tagggggaat aaaactagga 343860 ctacaattgt aaactcttct gatatagaaa caattactga taaacagtgc attggacaat 343920 ttgcagaaag atgcaaacat gatagaatca aaatctaaac aagatatgac aaagaaaaac 343980 aaaaatggaa ttgggaaagc atttggaatt ggacatctgg taataaaatt ctattgcaaa 344040 aaaatatata gtaaagaatt ttcagaagcc ttcacttgca ttagtgcaca accactggtt 344100 attcaacaac tacaatgtat acttgctggt actgaagtac aagattatac ctactcagac 344160 aaacaattag gtattggaca tactactgtc tatgtagaga ttaaatgata gtgtaaaaag 344220 gttgatcata ttataggtaa aagagctgaa atctggcatt gcagattgaa atttctgaaa 344280 actgaaataa taaaactaat ttcactaaag tatgtacatt ttcttattta catagtttat 344340 aatgtgttat ataattcatg aatcttcaaa agaaatatac tgagctattc aataaaaatt 344400 tacattacag ctttaggcca ccaagcccca tctattgatt atgtacttgg tgtaaattgg 344460 cggggggaac aaaacaagag tgaaaactga gcctcaaaat acaaagcatg tagcaaaaca 344520 gactactaaa attattctca atttctaagc ccattatatg atgcaggaga attcttatgt 344580 gtaggtaata aagaatctgt tcaaatatgc atcagtggta tgacagtttc aaataaccca 344640 ctgaactagg aaatattcac caccaaggag gtcaggtata ctgatttggt caacctggat 344700 attgacatgg gatgttctta cggattgaca gctccacttg atgctatcct atcacaaaat 344760 attattacct gatgttgata taattaacaa gtcaatacaa aaagtaaggt ctctctacaa 344820 gacaagacta acatctctgt aatataaatg ggactctgag tgtaatagat ttagggtttc 344880 tgcaagaatt ttgaaagtta aggatccaac gcctgtaatc ccagcacttt gggaggccga 344940 gacgggtgga tcacgaggtc aagagattga gaccatcctg gccaacatgg tgaaaccccg 345000 tctctaataa aaatacaaaa aaaaaaaaaa aatagctgga catggtggca cacacctgta 345060 atccccgcta ctcgggaggc tgaggcagga gaatcgcgtg aaccagggag gcagaggttg 345120 cagtgagccg agatcgtacc actgcactct ggcctggcaa cagagcgaga ctctgtctca 345180 aaaaaacagg aaagcaaaag aaaaagttaa ggatcctacc aacaaaattg gaatatgaga 345240 ctgaggaaat tcctattcca gctaaaccca gaattgatta tgttgatgaa cacatgaatt 345300 tcatgtgtgt gaaaacatat gaactcctca ttgtcagtct aatgagagtg aaaacaacac 345360 atcgaagatg cggggagacg acaatacaga gtgggctcat aactgcattc tagatactgg 345420 gattactttc cattaaggta tataatttta gaatatctca caaatagccc atgcaaaatc 345480 ctgcggaaag gcaaccataa atatagagag aatatgtaaa aaagtggcat ggtctagtat 345540 atgccaaaca aggcaagggt atacaaaaac ctcaaggtcc cagtatgaca aatcatgctt 345600 gtattgcaca cccattaaaa agtcttctaa aaagtttttt taatggtgtg caggcaggtt 345660 tattcagaaa aagctcggat tcatacttgt aaaagtctga gaaaagcatt aaaatgctat 345720 tatgatacag ttgacccaaa caacacaggt ttgagctgtg caggtccact tatctgtgga 345780 ttttcttcta cctctgccac tgagacagaa agacaaactc ctcctgctcc tcagactact 345840 cagcatgaag atgaggatga agacctttag gatgattcac ttcttcctaa tgaatagtga 345900 atgtattact tccttaataa cgtttttttt tctctagctt cttgtaagaa tacagtatat 345960 aatatatgca acacaaaaaa tacgtgttaa tcaactgctt tatgttatca gtaaggcttc 346020 cagtcaatgg gagactaact actaattaag tttttgggga gtcaagttat atgcagattc 346080 tccactgagc aaatgttcag cactcttaac tcctgtggtg ttcaagtgtc aactgtatat 346140 atgtttaaga gttattgttt acccagtaga tcaagccaag accaagttag gtttatgtgt 346200 ttttggctta acctaagaaa atgttcagac taaagcagtc catcaataga acagactgcc 346260 ttttaaacca gggaacaact tgtctttgta ggtattttag gtatatgaat gaccatatgt 346320 gatctgcttt gggtcatcta tggtcccttc caacttaaaa cttctctatt catgaacatt 346380 gcataactga attgtggatt tcatataaat aatatcttgt tgcctacttt aggtttgaaa 346440 tgttttcctt ctcagttgca tagatatgta tagcaccatc cccactatga actctcatgt 346500 agaaaatacc agattctaaa gtcatctgtg aggctaaatg tcagacttag gcacttccac 346560 ataatgctgc aaaaagcaac agcttaaagg tattacttgc tcaacatgtc attccaaaca 346620 catacactat gattagcagc tgaatttaac agtatctttc cactttgaaa aacactttat 346680 atacctttac aaagaagcca tagtatctca gggtagaaaa actcaacagg tagaaaacat 346740 ggccttctct tagaaatgag ctacgtaatt ttgagtactt atctcaaaat cattgcagaa 346800 acatatctag tgcttatgga aaaagaatca aaagatcttt ttttttagct aaagattttg 346860 agtttttctt gtgacattta agtcttttaa tgtatgctga tttttatgat tatctaactg 346920 tttcataatg gttattcttg cctccatgaa agggaagact agaacaaaaa cctgacaaga 346980 acaagttcta gctccatcac cgacttactg agtgacccta ggcaaatcat gtgggctctt 347040 tcttgtgttt taagttttac ctccaatgaa gtaactgcct cagactagct gtgaagctct 347100 cataaagtga tggatttgaa aatgccttgc aaagaatgag cagttaatac atagaaagtt 347160 tcatgtactt ccgtatattg catgatgccc acccagggtt aggttgataa cagttgttga 347220 tccaataatg aaagaaataa aaagaactct ttaaaataac gaagtaaaat agctaatttt 347280 cctgttgtag ttttaaaaat tatataaact atataactaa acatatttat gtttattata 347340 tataatatga tatgcaatta cataagacat tattatataa tgtttttata taatgcttaa 347400 gtaattaaac aattatattt aaatataagt tatactttcc ttccccagat aagacaaaga 347460 acctgtttac ttctctgagg gatttattgg ttcctgtgaa atctgtggag gccgctaaca 347520 ctccatagcc agagaatgac aacatatgat tttcttttca gtcttgtagt atccacagta 347580 gtgatgtctg tccatgtaca agtgtctgtc caggacatcc attaaattcc atgcctgctc 347640 tgtgtgttat gagggcaggg acagaagaca gattcactgg tggtactttc aaacaatgtg 347700 gtaggccttc cttttggggt ctgccatgac aatgataccc caggcggcaa tgctaaggcc 347760 catgaccatc ttcataatgg tccatggacc cggggggtat cccatcttca tgggcttctg 347820 tgccacccag tacacatacc cgcctgcccc catcagccgc aacccagaaa gcacgtgaca 347880 gctccagcag gtctccaaca ggtggtgttc tgctggtgag gtcggcgatc cgggtgtagc 347940 tggggttgca ggcttggcag gcacggcggc ggtatcggga ggcacagcga tcttgaggga 348000 ctcaaaaggc tgggacaact gagaccccgt gttctggaac tcggcctccc taaaaattat 348060 gttttaaaaa atacatagaa tcggtaagat gaggaaaaag cataaaacgg tcaaaaacac 348120 tgggataatt caaggttcat tttgacaatg gtaatacaaa tagaaaaact gacaaaaaag 348180 aaaatacatc ttacattaga aaacatacaa gagtagttgt atacaaacga agacacgtac 348240 caaaaataag ttacaaaata tgaatgcata tacataaaaa atgtagtttc aaacaattca 348300 aaagtaaaat gatgcaagac attaaaatat tcacaaacac gctcgaaaaa taagagctga 348360 cgcccaaatt agaccagttc aacggaagtg tggggtgtgg ttggggatcc gccgcagaaa 348420 tcacgtggcg cccaggccaa ggctgcaatt tcccatgctg cttggagaag acgcctggga 348480 gggctcccac catgcccagg ggcaggctat gtgactgccc ggtctgcagc tgtaagtggt 348540 ttctgggcca gtctctttgt ctggtcatga cctggttggt ggccctagct tgtgccgagt 348600 ggtcccggag tggcccaggg ggttgtgtgt ggggagccag cgtgggcagc ggaggtgctc 348660 cctggggcct gcagtagggc acagcctctg catcttgtgt gagcccagtg acccgcctgt 348720 cctgtccttc cagggttggg tggcagggag ggccaagggt gccctgcgtc cgtgacgggt 348780 cagcgtttcc agcaaatggg tccatggagg gagagcctag ctgagccggc gggctctacc 348840 accttcatga ggttctgttt ggacacctgt cctactcctg ttcccccaga tggtgaccat 348900 ggaggaagac ttgtgttggg cccaatggcc ctcggccagt gtccgtctgc caggtgccag 348960 cccccggtgc gctgaagctc aggccattcc tgatgccctg gcctcctgca ctgagctgtg 349020 gtgagcccat ccgggtcctg ctggatacat gggcggggag gggggtgccc tgggttgtgt 349080 tgatgatgag aaccttatat tatcctgaag agaggtgatg acttaaaaat catgctcaat 349140 aggattacgc tgaggcccag cctaggtgag aattttggaa gaggatgctg ggatccagag 349200 gcccccgacg gggccactgt atttcgggct gcagacctag aggccctgaa gggcatctga 349260 aggtggccca agcctatctc tgagcaaccc cgtgaggcag tcaaggatcc ctgtgtgggc 349320 ataggctggg gctctggttc cctaggggca gggcatgtgg gtggctcctc cctgaccccc 349380 attctcccct gtgtctttca gtgagctctt ctgcccaggc aggccccctg gcattgaccg 349440 gcataggtga gtggatcctg ctggggtcat gggccatgag ccaggctgct ggggtcgcca 349500 agggtcagcc tttgggacag gagggtttcc ttagggagcc aacctgaatc cccactgggg 349560 agggctaggt tctccaggag ggcagcttcc ttgggagtct gacccaagga ggatatcttc 349620 tctaaagccc tgcagtggtg agggtggtcc aggcagcaaa gggttccttc aaccccaccc 349680 aggacagcgc ccagctgaga ctcagtgtgc aggtctggcc atgaggactg cccaggtcac 349740 ataagggggt ccataggagc tccggggcac cacaggggtc acacaggagc tctccttccc 349800 cagagagggg tgagcgattg ggcctatggg gtcaggcctt tggagatcaa ggattgggcc 349860 ccacccatga acctgaatgg gactgagcct ttgagcaatg gaccatccca gtggtgcctc 349920 ggagcctagt cgggggtgat gtggcttcaa gggggttggg tcaaggctga gctctggccg 349980 gtgcctggta gtgctgcagg ctggccctgg gactcgctgg ctttgggcaa aggggccagc 350040 ccgtgtccca ctggaggtca ccccttccct gtgggcaact agcaggaagg gtggcatcct 350100 tagctgggaa ggcccactgt cgagggtcct gtccagggaa tttgcctccc aggcttcttc 350160 tgatccacgg actcacctcc agggtggtgg ggtcttgggc ccgaggaaag gagaagatac 350220 cctgtgttcc ccagttggct gagtgtggct tggctctgtg tttgggaggt gtgtagggta 350280 tgaatgggga cccaccagag aacacacatg gcccagggcc ccaggttatg atttcccatg 350340 cacacttgga gagaactctg ggtgagtgcc ctccactccc aggcacaggc tatgcaactg 350400 ccaggtctgc agtggcatgt ggcttccagg tcagcctcct tggttggcca tgagcaggtt 350460 ggttgccctg tcctgtgccc agtggtcttg gagtggccca ggggtcctgc aggggagctg 350520 gtgtgggtag tggaggtgct tgtggggcct gcaatagagc gcagcctagg tgccttgcac 350580 gagctcagtg acccacctgc cctgtcctag tcctagctca gtgacccacc cccgctttgc 350640 agtgatgggg agtaccaagc gtctcctgcg tctgtgatgg gtcagtgttc ccatcacatg 350700 ggtccatgga gggagagcat gcatgagctg gcaccaccca ccaccttccc actatggagg 350760 cgtgaggcca tgtttggaca catgtcttct tgtcccccca gacagtgagc ctggaggaag 350820 acttgccctg gtcccactgt ccctgggcca gtgtccatca gccaggtgcc cagaccccag 350880 tgcgctgaag ctcagccctc cctggcactc tggtctcctg cactgagctg tggtgagcac 350940 atccaggtcc tgctggatgt ttgcatgggg aggggctttc cccgggttgg gtcgatgatg 351000 agaagcttct gttttcttga agagaggtga tgacttaaaa atcatgctca ataggattat 351060 gctgaggccc agcctaggtg agaattttgg aagaggatgc tgggatcccc ggcaggaggg 351120 attttgggct ggagacctgg aggccctgaa gggtatctgc aggggcccca tccctgtctc 351180 tgcacttgtc tgtgaggcag cccagtttcc ctgtgtgggc ttcgtgtcag tgctctggtt 351240 ccctggagca gggcacgtgg gtggctcatc cctgaagtca cgttctccct ttgtgtcttt 351300 cagtgagctc ttccgcccat gagggccccc tggccttgag cagcataggt gagcggatcc 351360 tgctgggctc atggaccagg ccacatgggg tcactgaggg tcagccttca ggacaggagg 351420 gattcctcag ggagacaacc tgaatcccca ctggtgaggg attggttctc caggagaacc 351480 acctccttgg gaatctgacc caaggaggac accttccctg aagccctgca ggagtgacag 351540 tggtccaggc aggaaagggt tccattagtc ccatgcaggg cagctcccag ctgagacttg 351600 gtgctagggt ctggcctcga ggactgccca ggccacatga ggcagggtct caggctgcta 351660 tttccagtgc atgcttggag agggagcctg ggtaggcccc ctccctgtgc aggggcaggc 351720 tgtgcatctg ctggggctgc agcggtgcct gccttcagga ccagcctcct tggttggctt 351780 gagctggata gtggccttgg ccccacccag gggtcatggt gcagcccagg aattgcaggg 351840 gagctggcat ggggagtgga ggtgctccag gggcttgcag tagggcacag cctgggcatc 351900 ttgcttgagc ccagtgacca gcctgccctg ttttccaggg ttcagtggca gggaggacca 351960 agggtccccc acgtccatga ctatcactgt ttcacatgga tcccatcagg tgggtccatg 352020 gagggagagc atgtgtgagt cagcaccccc tgcctccttt cccgcatgga ggcatgaggt 352080 tctgttcgga cacttttccc tgtctctcca gatggtgacc ctgaaggagg acttgtgttg 352140 ggcccaatgg cctggggcca gtgtctgtca gccaggtgcc cagcccctgg cgtgctgaag 352200 tttgggccct tcctggtgcc ctgttctatc gggggaaccc gcccccaata attcaacgta 352260 ggtccttttc tattttccct aagtgtcggc cggtctgaga aataaaggga aagagtacaa 352320 aagaaagaaa ttttaaagct gggtgtccgg gggagacatc acatgtcggc aggttccatg 352380 atgccaccca agctgcaaaa ccagcaagtt tttattagtg attttcaaag gggagggagt 352440 gtacaaatag ggtgtgggtc acagaaatca catgcttcac aaggcaataa aatatcagaa 352500 ggcaaatgag ggcagagcac cagggccaaa ttgaaattgc taatgaagtt tcgggcacgc 352560 attgtcattg ataacatctt atcaggagac agggtttgag agcagacaac cggtctgacc 352620 aaaatttatt aggcaggaat ttcctcgtcc taataggcct aggagcgctt cgggagacca 352680 gggcttattt catcccttat ctacaactgt ataagacaga cattcccaga gcggccattt 352740 tagagacctc cccctaggaa ggcattctct ttctcagggt tgttccttgc tgagaaaaat 352800 aattcagcaa tatttctcct attcgctttt gtaagaagag aaatatggct ctgttccgcc 352860 cggctctcag gcagtcaggc ctgatggttg tctcccttgt tccctgaaca tcgctgttat 352920 cctgttcttt tttcaaggtg cccagatttc atattgttta aacacacatg ttttacgaac 352980 aatttgtgca gtgaacgcaa tcatcacagg gtcctgaggc gaaatacatc ctcagcttac 353040 gaagatgacg ggattaagag attaaagtaa agacaggcat aggaaataat aagagtattg 353100 atttgggaag tgataaatgt ccatgaaatc ttcacaattt gtgttcttct gccatggctt 353160 cagcaggtcc ctccgtttgg ggtccctgac ttccctcaac actggtctct tccactgagc 353220 cttggtgagc ccatctaggt cctactggat gcatgtgtgg ggaggggggt gccctgggtt 353280 gggtcaatga tgagaacctt atattgtcct gaagagaggt gatgacttaa aaatcatgct 353340 tagtaggatt acgctgaggc ctagcctagg tgagaatgtt ggaagaggat actggatgct 353400 gaggtccctg gctgagctac tgtattttgg gatggagatc tggtgactct aagggcacct 353460 gaagggccag accctgtctc tatgaggcag cccaggctcc ctgtgcaggc ttgctgttgg 353520 cactctggtt ccctggggtg ggacatattg gtggctcctc cctgagccct gttctcccct 353580 tgtgtctttc agtgagctct tccaccaagg agggccccct ggcattgact ggcataggtg 353640 agtggatcct gctggtgtca tgggccatgg gccaggccac gtggggtcac caagggtcag 353700 ccttcaggaa agaagggttt cctcagggag ccaaactgaa tccccactgg gaagagatgg 353760 gttctccagg agggcggctt cctgggaaac aggaaccaag gaggacgcct tccctgaagc 353820 cctgcagggg tgacggtggt ccaggcagga aagggttcct tcaattccac ccagggcagc 353880 tcccagctga gtctcggtgc tcgcgtctgg actgccctga ctatgtgggg ggccacaggg 353940 gctctggggt gccttggggg tcacacaggt gctctttgtc cctggagaaa ggtgggtgat 354000 caggcccatg gagttgagca gtggagattc aaggattgca cctgacacat ggtcctgaat 354060 ggaacccacc ctgttgagca atgggccatc ccatgggcct cttcaagcct gaagaggggc 354120 ggtgctgttt cactgggttt aggtcaaggc tgagctctgg ccggtgcctg gtggtgctgc 354180 agtctagctg ttggactcgt gggctttggg ccagtggggc agcctgcatc cctctggaag 354240 tcaccccttc cctgtggctg gaagttaccc cttcccagtg ggcgaatgtg gggaagggtc 354300 acctcctgaa gtgagaaggc ccactattga gggtcctgtc ctggcaattt gctgcccatg 354360 ctgcttctga gccatggaga cacctccagt gtggtgggat cttgggccca aggaagggag 354420 aagacactgt gccccccgat tagctgagtg tggccaggct gtgtgtttat gaggtgtgag 354480 gggcatggat ggaaactcac cagagaaagc atgtggccct gggaccccag gtcgtggttt 354540 ccagtatgtg cccagataca gcacatgggt gggtgcccac catgcacagg gactggctat 354600 gtgactgcca gctgtgcagc agcatcaggc atatgggcca gcctccttgg ttgacaatga 354660 actggttgct ggccctggcc tgtgcccagt agtcctgggg tgaccctggt gtcatacagg 354720 ggagctggca tgtgtagtgg aggtgcttgt ggggcttgca gtagggcaca gccctggctt 354780 ctagcctgag cccagtgacc tgcctgtcct atcctttcgg tgttcagtgg cggagagagc 354840 attgggtgcc ctgcatccat gatgggtaag tattccacat ggatctcatc acatgggtcc 354900 atggaaggtg agcatccctg agctggcaca ccacaccttc tgtccacatg gaggggtgag 354960 gttgtgtttg ggcacttgtc ctcttcctgt tccttgagat ggtgacccca gaggaggaca 355020 tgcgttgggc ccgctgtccc tggccagtgg ccatcagcca agtgcctagc ccctattgca 355080 ctgaaactcg ggcccttcct gtcaccttgg tctcctgcgt tgagcttggg tgagcccatc 355140 cgggtgccac tggatgccta ggcagggagg ggggtgccct gggttgggtc gatgatgaga 355200 actttatatt gttctgaaga gaggtgatga cttaaaaatc atgctcaata ggattacgct 355260 gaggcccagc ctaggtgaga attttggaag gggacactag aatcccgagg tccccagcag 355320 ggctgctgta ttttaggctg gatacctcga ggccctgaag ggcacctcat ggaggggccc 355380 aatcctgtct gtgctcctct attaggcaca ccagactttc tgtgtgggct tggtgtccac 355440 gctcagcttc cctggggtgg gacacgttgg cggctcctcc gtgagcccca ttatcctctg 355500 tgtctttcag tgagctcttc cccccagcag acccctggga ttgacgagca taggtgagtg 355560 gagactgctg gtgtcatggg ccatgagcca agctgcgtgg ggtccccaag ggtcagccct 355620 cgggccacct gggtttcctc aggagctgat ctgaatccca actggggatg tgttctccag 355680 gagggcagct tccttgggaa tcagacataa ggaggaggcc ttctctgaag ccccgcaggg 355740 gtggcagttg tccaggcagg aaagggtttc ctcagcccca cgcagggcag tgctcagctc 355800 agacttggtg cttgggtcag gcctctaaca tggccaggcc acatgagggg ggcaacaagg 355860 gctccgggga gccaagggca tctcacgggg gctctccaac cctggagaag ggtgggtgat 355920 tcggtccatg gggtcaggcc atggagattc atggattgca gcaaacccag gaccctcaat 355980 gggactgacc ctataagcag tgggccctcc cagtggcacc tctttgagcc atttgtgggg 356040 cggcgctgtt tctctgaggt tgggtcaaga ctagctctgg ccagtgcctg atggtggtgc 356100 aatccactcc tgggactcgt gggctctggg ccaaggctgc agcccatgtc ccgctggggg 356160 tcaccccttc attgtgggcg agtggcagta atggcctcct gagttgggaa ggcccgcagt 356220 ggaaggacct ttcctggaaa tttgcagtcc aggctgcttc tcagccatta ggacaactcc 356280 agcgggttgg ggggcagggg cgggtcttag gcccaaagaa aggagaagat accatatgtc 356340 tcccggttgg ctgagtgtgg ccctgctgtg tgtgtgggag gtgttgtgtg gggcatggat 356400 tgggacacac cagagaaagc ttgtggccct ggagccccag gctgcgattt ccagtgcacc 356460 ttgaggaaag gagggtgggt gccctccatg cacagggcag actgtgcaac tgccaggtag 356520 gcaacagcac gtggtgtccg ggccagggtc cttggtttgc tgtgagctct ttggtgtccg 356580 tggcccctac ccaaggatcc agataccacc cggggtcatg caggggagct agcatgggca 356640 atggaggtgc tcaaggggcc tgcagtaggg cacagcccag gtgtcttgcc tgagcccagg 356700 aacccacctg ccctgtcctt ccatggttca gtggctggga gagcaaaggg ttccgctgat 356760 ctatgacaca tcagtgtttc ccatggatcc catcacatgg gtccacggag agagagcatg 356820 tgtgagctgg cacccccaac cccattccct gtatggaggc gtgagcccat ggttggacac 356880 atgtcctcct cctgtccccc cagatggtga ctgtggaaga agacttgctt tgggaccgct 356940 ggccccaggc cagtggttgt catccaggtg cccagccctt ggtgcacttg agctcaagcc 357000 cttcctggtg ccctggcctc ctgccctaag ctgtggtgag cccatccagg tcccactgga 357060 tgcatgcatg gggaggaggg tgccctgggt tggatcgatg atgagaacct tatattgtcc 357120 tgaagagagg tgatgactta aaaatcatgc tcaataggat tacgctgagg cccagccttg 357180 gtgagaattt tggaagagga tgctgagatc ccaaggtctc tggcagggcc actgtatttt 357240 gggctggaga cctggaggcc ctgaagggca tcttaggggt gcccgacccc atctctgcgc 357300 tcctccttga ggcagcccag gctcccttgc gggcttggtg tcagccctcc agttccctgg 357360 ggttgaggca cattggaggc tccttcctga gcccccattc tcccctgtgt ctttcagcga 357420 gctcttctgc ccagggggac ccctggcctt aagtgggata ggtaagtgga tcctgctggg 357480 gtcgtggacc atgagccagg tcgctttggg tcactgagag tcacccttca ggccacgagg 357540 gattcctcag ggagcccatc tgaaacccac cagggacgga tggtttctcc aggaggacag 357600 cttccttgga agtcggtccc aagaaggatg ccttccctga agccgtgcag agatgatgga 357660 cgtccaagca ggaagggctt ccttcaactc aatgcagtgc acatcctagc tgagactcag 357720 tgcacaagtc aggcctggag gacttcccag gccacatgag ggggtccaca gggtctccag 357780 gggccacggg tgttatgagg gtgctctctg tccccgaggc ttgcagaggg gcagggtgtg 357840 ggtgatcgga cttatggagt caggccgtga agattcaagg attgggccca acccatggcc 357900 cagcatgggc cgaacctgta gagcaatggg ccatcccggt ggtgcatcct tgagccttgt 357960 gggggtggtg tgaccttagt ggggttgggt caagcctgag ctctggcctt cacctggtgg 358020 tgctgcaggc tggccctggg aatttgggct ttgggccaag ggtgcagtct gtgtcccgct 358080 aaaggtcacc cctccccaaa gtggagtggc cagaaggatg gcatcctgtg gtagaagtcc 358140 cactgtcaag ggtcctgtcc tggcaatttg ttgcccaggc tgcttctaag ccatgggttc 358200 acctccaaag tggcggggtc ttgagccgaa ggaaagggga agacatcatg tgttccctga 358260 ttgactgagc atggcctggc tctgcatttg gaggtgtgcg gtgcacgaat ggggacccat 358320 cagagaaggc atgtggccct ggggctccag gatttgattt ctggtgtgag cttttacagg 358380 gggtctgtag tggcacgtag cattcaggtc agcctacttg gtttgctctg agcttgttgg 358440 tggtcctggc cctgcccagt ggtcccattg tggcatagag tcatgtgagg gagctgtggc 358500 aaggagggcc aagggttccc cacattcatg atcgttactg tttacatgga tcccatctct 358560 tgagtccatg gagggacagc atgtgtgagc cagcaccccc tgcccacttt cctgcatgga 358620 ggcgtgaggc cgtatttcta tacgtgtccc ccacccctcc agatggtgac cccagaggaa 358680 gacgtgcatt gggtccgctg gccccaggcc agtgtctctc agccatgtgc tcaacacctg 358740 gtgagctgaa gctcaggccc ttcctggcat cctggtctcc tgcactgagc tgtggtgagc 358800 acatctgggt tcctctggat acgtgtgcag ggagggggat gcactgggtc gggtcaatga 358860 tgagaacctt atattgttct gaagagaggt gatgacttaa aaatcatgct caataggatt 358920 acgctgaggc ccagcctagg tgagaatttt ggaagaggat gctgggatcc caagttcccc 358980 agcatggcca gtatatttta ggcaggagac cctgaggctc tgaacggcat ctccgggggg 359040 cacaaccctg gctctgggct cctctgggag gcagcccagg ttccctgtgc aggcttgggc 359100 tctggttccc tgagccccca ttctccctcg tgtgtttcag tgagctcgtc ctcctaggtg 359160 gggcccccag gcattgaccg gcataggtga gtggtcctgc tggggtcatg ggtcatcagc 359220 aggttggagt caccaagggt cagcctttga gacaggaggg tttccacagg cagccgacct 359280 gaatccacac catggaggga tagattggtc ctccaagagg gctgtttttt ttcggaatca 359340 gacccaagga ggataccttc cctgcagccc tgcggggatg acggtggtcc aggcagggaa 359400 gggttccttc agtctcacgc aggtcagctc ccagctgagt ctcagtgcat tggtctggcc 359460 tccaggactg accaggccac gtgagggggg caacaggggc ttcgggatgc agtggggtca 359520 cacaggatct ctccatcccc agagaaaggt gggcatagaa cccatggatt cgagctgcag 359580 agattcaaga atcgcacacg aattattgcc ctgaatggga cccaccctgt tgagcaatgt 359640 cccatcccag ggcacctctt tgagcctgaa gggggtggtg ctgtttccct aggtttgggt 359700 caaggctgag ctctggccag tgcctggtgg tgctgtagtc ctgtcatgga ctcgttagct 359760 ttacgccaag gggtcagccc acgtcctact ggggatctcc ccttccctgt ggctggaagt 359820 caccccttcc ccattggcaa gtgtcaggaa gggtgacctc ctgaggtgga agtcctgttg 359880 agggtcttgt ccctggaata tgccacgcat gctgcttctg agccatgggg tcacctccag 359940 ggtagcgggt cttgggccca aggaaaggag aagtcaccat gtgtcccccg attagccaag 360000 tgcggccctg ctctgtgttt aggaggtgtg tggggcatgg atggggaccc accagagaaa 360060 gcatgtggcc cagggacccc aggttgcaat ttctaggaca tgctgggata gggcacctgt 360120 gtgggtgtcc acagtgcaca gggataggct atgtgacttg caggtctgca gcggcatctg 360180 gcatccaggc cagcctcctt ggtgggccgt gaactgaatg gtggcgctgg cctgtgccca 360240 gtatatctgg tatgaccctg gggtcgtgtg ggggagccgg catgggcagt ggaggtgctt 360300 atgggacctg cagtaggaca cagtcggggc ttcttgccca agcccagtga cccgcttgcc 360360 ctgtccttcc agggttcggt ggctgagaga gcttttgttg ccctgtgtcc gtgacgggcc 360420 agtgttctgc atgcatccca tcacatggat ccatggaggg tgagcatccc tgggctgaca 360480 caccccacct tctgccccca tggaggggtg aggttgtgtt ttcacacctg tcttactcct 360540 gtttccccag atgttgagcc cagaggaaga cttgcactgg gcccaatggc cccaggtcag 360600 cgtccatcag ccaggtgtcc agcccctggt gcactgaaga tcgggccctt cctggtgccc 360660 tggtctcctg cattgagctg tggtgagcac atccggatcc tgctggatgc gtgtgcgggg 360720 aagggggtgc cctgggttgg gtcaatgaga accttatatt gtcctgaaga gaggtgataa 360780 cttaaaaatc atgctcaata ataggattac gctgaggccc agtctaggtg agaggtttgg 360840 aagaggatgc tgggattccg aggtccccag gagggcccct gtatttttgg ctggagacct 360900 ggaggccctg aagggcatct tgtgggtgcc caaccctgtc tctgcgctcc tccttgaggc 360960 agcccaggct ccctgtgcag gcttggtgtc agccctccag ttccctgggt ttgaggcaca 361020 tgggaagctc ctttctgagc cccgttctcc tcttgtgtct ttcagtgagc tcttccacat 361080 ggaagacccc tgtcattgac tggcataggt gagtggctgg catcatgggc catgagccag 361140 gccgcgtgag gtcgccaagg gtcagccttc gggaaagaag ggtttcctca gggagccaac 361200 ctgaatcccc actgggaaga tatgggttct ccaggagggc gacttcctgg gaaacaagaa 361260 ccaaggaggt ccccttccct gaagccctgc aggggtgacg gtggtccagg caggaaaggg 361320 ttccttcagt tccacccagg gcagctccca gctgaggctc ggtgcttgcg tctggactta 361380 aggactgccc tggccatatg aggggtgcca cagtggctct ggggtgccat ggggtcacac 361440 aggcactctc tgtccctgga gaaaggtggg tgattgggcc catggagttg agctgttgag 361500 atgcaagttt tgcacctgac acatggccct gaatgggacc caccctgttg agcaatgggc 361560 catcccatgg gcctcttcga gcctgaaggg gggcggtgct gtttcactgg gtttaggtca 361620 aagctgacct ctggccgcca cctggtggtg ctgcagtcca gcccttggac tcgtgggctt 361680 tgggccaagg gggcagcctg catcccactg aaagtcaccc cttccctgtg gctggaagtt 361740 atcccttcct catgggcgag tgttgggaag ggtggcctcc tgaagtggga aggcccgcta 361800 ttgagggtct gctcctggca atttgctgcc catgctgctt ctgagccatg gagtcaccac 361860 cagtgtggtg gggtcttgga cccgaagaaa ggagaagaca ctgtgccccc cgattagctg 361920 agtgtggcca ggctgtgtgt ttgcgaggtg tgaagggcat ggatggagac tcaccagaga 361980 aagcatgtgg ccctggggcc ccaggttgtg gtttccagta tgtgcttgga tatggcatat 362040 gggtgggtgc ctaccatgca cagggactgg ctatgtgact gccagctgtg cagcagcatc 362100 aggcatacgg gccagcctcc ttggttgacc atgaactggt tgctggccct ggcctgtgcc 362160 cagtagtcct ggggtgaccc tggtgtcatg taggggagct ggcatgtgta gtggaggtgc 362220 tcgtgtggtc tgcagtaggg agcagccctg gcttctagcc tgagcccagt gacctgcctg 362280 tcctgtcctt tcagggttca gtggcggaga gagcatcagg tggcccacgt ctgtgatggg 362340 ccagtattcc acatggatct catcacatgg gtccatggaa ggcgagcatc cctgagctgg 362400 cacaccccac cttctgccag catggaaggg tgaggttgca tttggcacct gtcctcttcc 362460 tgttcctcga gatggtgacc ccagaggagg acttgcattg ggcccactgt ccccgggcca 362520 gtggccatca gccgggtgcc tagcccctgt tgcactgaag ctcaggccct tcctgttgcc 362580 ctggtctcct gcattgagct tgggtgagcc catccggttg ccactggatg cctaagcagg 362640 gaggggggtt ccctgggttg ggtcaatgat gagaacctta cattgttctg aagagagatg 362700 atgacttaaa aatcatgctc aataggatta cgctgaggcc cagcctaggt gagaattttg 362760 gaagaggacg ctgggatccc taggtccctg acagggccac tgtattttgg gctggagacc 362820 tggagtcctt gaagggcatc tggagggggc ccaaacctgt ctctacgttc ctccatgagg 362880 cagtccaggc tccctgtgcg agcttcgtgt cggtgctcag attccccttg gtggtgcatg 362940 tgggtggctc atccctgagc ccctgttctc cccttgtgtc tttcagtgaa ctcgtttgcc 363000 caggaggacc cctggccttg agcagcatag gtcagtggat cctactgggg tcatgggcca 363060 tggaccaggc cacgtggggt cactgagggt cagctatcag gacaggaggg attcctcagg 363120 gagacaacct gaatccccac tggtgaggga ttggttctcc agaagggccg cctccttggg 363180 aatctgaccc aaggaggaca ccttccctga agtgctacag gagtgacatt ggtccaggca 363240 ggaaagggtt ccattagtcc catgcaggtc agctcccagc tgagacttgg tgctagggtc 363300 tggccttgag gactgcccaa gccacatgaa ggtggcccca ggctgtgatt tttggtgcgt 363360 gcttggagag ggagtctggg caccctccct gcacaggggc aggctgtgcg tctgccaggt 363420 ctacagtggc gcctagcttc agagcaagct tccttggttg gccttagctg gttggtggcc 363480 ctggctccta cccaggggtc acaatgcagc ccaggaagtg cagggaagcc ggcttggaca 363540 gtggaggtgc tccaggggcc tgcggtaggg cacagcctcg gcatcttgcc tgagcctagt 363600 tactcgcctg tcctgtcctt ccagggtttg gtggtgggga gatacaaggg ttccccaggt 363660 ccataactgt cctcgtttca catggatccc atcacatgag tccacggatg tagagcatgt 363720 gtagccagca gcccctcccc gctttcctgc atggaatctt aaggccctat ttggacacct 363780 ttccccgtcc ctccagatgg tgagcacaga ggaagaattg cgttaggccc tttggccccg 363840 gaccagtgtc tgccagccac gtgctcagcc tcccgtgcgc taaagctcag gtccttcctg 363900 tcatcctggt atcctgcact gaggtgtggt gagtccatcc aggtccctct ggatgtgtga 363960 gtggggatgg gggtgtcctg ggttgggtcg atgatgagaa ccttatattg tcctgaagag 364020 aggtgatgac ttaaaaatca tgctcaatag gattacgctg aggcccaact taggtgagaa 364080 ttttgaaaga ggatgctggg aatcacaagg tccccggcag gaccactgta ttttaggcgg 364140 gagacctcga ggccctgaag ggcatatcat ggaggggtac ccaacccagt ctgtgctcct 364200 ccattaggca caccaggctt cctgtgtggg cttggtgtct gcactcagct tccccggggg 364260 tgggacacat tggtggctcc ttcctgagtc gcattctcct ctgtgtcttt cagtgagctc 364320 ttccccccag caggccccct gggattgact ggcaaaggtg agtggatact gctcgtgtca 364380 tgggctgtga gccaagctgc gtggggtccc caagggtcag ccctcgggtc acctgggttt 364440 cctcaggagc tgatctgaat cctgactggg gatgtgttct ccaggagggc agcttccttg 364500 ggaatctgac acaaggagga ggccttctct ggagccctgc aggggtggtg gtggtccagg 364560 caggaaaggg tttcctcagc tccacacagg acagtggagc tgggcagtgc tcagctcaga 364620 cttggtgctc aggtcaggcc tctaggatgg ccaggccaca tgacgggggc cacaagggct 364680 ccagggcacc acagacatct catgggggct ctccaaccct ggagaagggt gggcaatttg 364740 gcccattggg tcgggtcatg gagcttcaag gattgcacca aacccatatc cctcaatggg 364800 accgacccta ttaagcaatg ggccatccca gtggcacctc tttgagccat gtggtgggtg 364860 gcgctgtttc tctgaggttg ggtcaagact agctccggcc agtgcctgat ggtggtgcag 364920 tccagtcctg ggactcgtgg gctttgggcc aagggtgcag cccgtgtcct actggggatc 364980 accccttcct tatgagggag tggtgggaag ggtatcctcc tgaggtagga aggcccgctg 365040 tggaaggaac tttcctggaa atttgcagtc cagactgctt ctgagccatg aggtcatctc 365100 cggggtggcg gggtcttggg cccaaggaaa ggagaagaca ccatatgtct cccgattggt 365160 tgagtatggc tccactctgt gtgtgggagg tgttgtgtgg ggcatggatt gggacccacc 365220 agagaaagct cgtggcactg gaaccccaag ctgcaatttc cagtgcacct tgggaagggg 365280 actgggtgct caccctccat gcacagggca ggctgtgcag ctgccaagtt ggcagtggtg 365340 cgtggcatcc gggccagcgt ccttggttcg ctgtgagctg gttggtgtcc ttgacgcctg 365400 cccaggggtc ccagtgctgc ttggggtcat gaggggagcc agcgtgggca agggaggcct 365460 gcagtagggc acagcccggg ggtcttgcct gagcccagga tcctgccggc cctgtccttc 365520 catggttcgg tggctgggag ggcaaagggt cccccacgtc tgagacacat cagtgtttca 365580 catggatctc atcacatggg tccatagaga gagagcaagc gtgagctgac accccccacc 365640 cccttccctg tatagaggtc tgagcccctg gttggacaca tgtcttcctc ctgtcccccc 365700 agatggtgtc tgtggaggaa gacttgccat tgggttgctg gccccaggcc agtggttgtc 365760 atccaggtgc ccagccttgg tgcactgaag ctcaggccct tcctggtgct ctggtctcct 365820 gcactgagct gtggtgagca catccgggtc ccactggatg ggtgtgtgtg gtggggggtg 365880 ccctgggttg ggtcgatgat gagaacctta tattgtctga agagaggtga tgacttaaaa 365940 atcatgctca ataggattac gctgaggccc agcctaggtg agaattttgg aagaggatgc 366000 tgggaattac aagttccctg tgaagtccac tgtattttga gctagagacc tggaggctct 366060 gagggcatct ggagggtgcc caaccctgtc tctgcactcc tccatgaggc agcccaggct 366120 cactctgtgg gcttggtgtc ggcgctcctg ttacccaagg gtggggtact ttggcatctc 366180 ctccctgagc ccccattctc ccctgtgtct ttcagtgacc tcttttgccc ggcagacccc 366240 ctggcattga ccagcatagg tgagtggatc ctgctggggt catgggtcat gagccaggct 366300 gtgtggggtt gccgagcatc agcctttggc tgcaagggtt tcctcaggaa ctgacccgaa 366360 tgcccacctg ggatgggttc tccaggaggg cagcttcctt aggaatcgga cccaaggagg 366420 ataccttcca tgaagccctg caggggttgt ggtggtccag gcagtaaagg gtttcctcag 366480 ccccatgcag ggcagcaccc agctgaaact cggtgcttaa gtcaggcctc taggatggcc 366540 cgtccacatg aggggaacca caagggcact ggggcgccaa gggggtctta tgggggctct 366600 ccgaccttgg agaggtatgt gtgattcggc ccatgaggtc aggttttgga ttttcaagga 366660 tctctccaaa cccatggccc tgaatgggac cgaccctatt aagctatggg ccatcccagt 366720 ggtgcctctt tgagccaagt gtggggtggc actgtttcca tgaggttggg tcaagactag 366780 ctctggtgac cccatgatgg tgctgcagtc tggccctggg actcgtgggc tttgggccaa 366840 gggtatagcc catgtcccac caggggccac accttccttg tgggcaagtg gcggacaggg 366900 tgtcctcctg aggtgagaag gcctgctgtg gaaggacctg tccaggctgc ttccaagcta 366960 tggggtcacc tacagggtgg tggggtcaag gaaaggagaa gacaccatgt gtctcccgat 367020 tggctgagtg tggccccact ctgtgtgtgg gaggtgttgt gtgaggcatg gatggggaca 367080 tatcagagaa cacacgaggc cctgggtccc caggctgcaa tttccggtgt ggtgtggagc 367140 agggcctggg tgcttgccct ccacacacag gggcaggctg tgctactgcc agattggcag 367200 cagtacgtgg catccaggcc agcctccttg gttggccgtg agacggtagg tggccctggc 367260 tgacacccag gggccagtac agccctgggg tcatgtgagg caactggagt gggtagtgga 367320 ggtgctcaag gtgcctgcag tagggcatag ccagggcgtc ttgcctgagc ccagtgacct 367380 acctgccctg tccttccagg gttcagtggt gcagagggcc aaagttcccc tgtgtccatg 367440 acacatcagt gtttcacatg gatcccatca catgggtcca tggtgggaga gcaatcgtga 367500 gctagcatcc cccaccccct tcctgcatgg aggcgtgagg ttccatttgg acacatgtcc 367560 acctcctgtc ccccagatag tgagactgga agaaaacttt cattgggccc gctgtcccgg 367620 ggtgagtggt catcagtcag gtgcccagcc cttggtgtgg tgaagctcag gctcttcctg 367680 gcgccctggt ctcctgcacg gagctgcggt gagcacatcc gggtcccgat ggatgcatgc 367740 gtggggatgg agggcgtgcc ctgagttggg tcaatgatga gaaccttata ttgtcctgaa 367800 gagaggtgat gacttaaaaa tcatgctcaa taggattacg ctgaggccca gcttaggtga 367860 gaattctgga agaggatgct gagatccgaa gtcccctgga agggccactg tattttgggc 367920 tggagtcctt gaggccctga aggacacctt cggggtgccc aacccagtct ctgcactcct 367980 ctgtgtggca gccaaggctc cttgtgcagg cttggtgttg gcattctggt tccctggggg 368040 tggagcacat cgacggctcc tccctgagcc cccgttcttc tctgtgtctt tcagtgagct 368100 cttctaccca ggcgggcccc tgcccttgag cggcataggt gagtggatct tgctggggtc 368160 acgggccaag agccaggcca cggggggtcg ctgagggtca cctttcaggc cacgagggtt 368220 tccttaggga gctgacctga atccccacca gagatggatg gtttctccgg aagggcagct 368280 tccttgttaa ttgatcccaa gaaggacgcc ttccctgaaa ccctgcaggg gtaatggagg 368340 cccaggcagc agagagttcc ttcaacccaa tacagtgcag cagcttgttg ccttgatgct 368400 ccccctccct ggagaaaggt gggcataggg cccgtggagt tgagttgcag agatttaagg 368460 atcgcacagg acttattgac ctaaatggga ctgaccctgt tgagcaacgt gcacttggtg 368520 catgggtcag gtgtggagca ctgcccaggc cacatgaggg gtccactggg tctctggggg 368580 ccacgggtgt tatgcaggag ctctccgtcc ccaaggcttg caggggggta ggatgtcggt 368640 gatcgagctt atgcagtcag gccgtgaaga ttcaaggatt gggcccaacc catggccctg 368700 atgggaccga ccctgttgag caatgggcta tcccactggt gcctccttga gcctggtggg 368760 ggcagtgcgg cctcagtggg cttggatcaa ggctgagctc tggccagcac ctggtgtttg 368820 gccctgggaa tcgtgggctt tgggccaagg gttcagcctg tgtcccactg gagttcatcc 368880 ctaccggaag tggagtggat ggaagggtgg catcctgtgg tggaagaccc accgttaagg 368940 gtcctgtcct ggcaatttga tgcccaggct acttctgagc catggagtca cctccagggt 369000 agcagggtct tgagccaaag gaaagttgag gacatcatgt gtcctctgat tggccgagcg 369060 tggcccagct ctgtgtttag gaggtgtgcg gtgcatgaat ggggacccac cagagaaggc 369120 atgtggccct ggggccccag gatgtgattt ctggtgtgtg cttataaagg gtgcctggat 369180 gggttcattt aatgcccagg ggcaggccat gtgactgcca ggtctgcagt ggtacgtggc 369240 atccaggcca gcctccttga tttgctgtga gctatttggt gcccatggcc ctgcccagtg 369300 gtcctgatgc agcccagatt cgagcagggg atttggcgtg ggcagtggag gtgctccagg 369360 gtcctgcact agggtgcagc ctgggcgttt tgctcgaacc ctgtgaccct cctgccccgt 369420 ccttccaggg ttcagtggcc aagggttcct cgcgtaaatg accatcactg ttttacatgg 369480 atctcatctc atgagtccat ggagggagag catgtgtgag ccagcacccc ctgcccactt 369540 tcctgcatgg aggcatgagg ccttgtttgg acacctgtcc cccacccttc cagatggtga 369600 ccccagagga agacttgcgt tgggcccact ggctctgggc tcagcccctg gtgagctgaa 369660 gctcaggccc ttcctggcac cctggtctgc tgcactgagc tgcggtgagc ctatctgggt 369720 cccactggat gcatgggttg cggggcagtg gagggtgatg ccctgggttg ggtcgatgat 369780 gagaacctta tattgtcctg aagagaggtg atgacttaaa aatcatgctc aataggatta 369840 cgctgaggcc cagcctaggt gagaattttg gaagaaggtg ctgggatccg gagttccctg 369900 gaatgaccaa tgtattttgg gctggagacc ttgaggccct gaacagcagc atctcgtggg 369960 ggcccaaccc cttctccgtg ctcctctgtg aggcagccca ggctccctgt gtgggcttgg 370020 tgttagtgct ccggttctgt gaacccccat tctccccttg tgtctttcag tgagctcttc 370080 cacccaggtg caaccccctg gcattgacca gcataggtga gtggtcccgc tggggtcatg 370140 ggtcatcagt catgcagtgt ggggtcacca agagtcagcc tttgagacag gagggtttcc 370200 acaggcagct gacctgaatc cacaccatgg aagggtaggt tggtcctcca agagggctgt 370260 ttttttggga atcggaccca aggatgatat ctttcctgca gccctgcagt gatgacggtg 370320 gtccaggcag gaaaagtttc cttcaatctc atgcagggca gctcccagct gagtctcagt 370380 gcactggtct ggcctcgagg actgaccagg ccacgtgagg ggggccacag gggctttggg 370440 atgccatggg gtcacacaag agctccccat ccctggagaa aggtgggcat agagcccatg 370500 gagttgagct gcagatattt aaggatcaca caggatttat agccctgaat gggaccgacc 370560 ctgttgagca atgtgccatc catcctatgg tacctctttg ggcctggatg gggtgttgct 370620 gtttccctag gttttggtca aggctgagct ctggccagtg cctggtggtg ctacagtcca 370680 gccacggact tgttagcttt aggccaaggg atcagtccac gtcctgctgg ggatctcccc 370740 ttccctgtgg ctggaagtca ccccttcccc attggcaagt gtgaggaagg gtggcctcct 370800 gaggtggaag gcctgctgtt gagggtcttg tccctggaat atgccaccca cactgcttct 370860 gagccatagg gtcacctcca ggatagtggg tattgggcca aaggaaagaa gtcaccatgt 370920 gtcccctgat tagccaagtg tggccctgct ctgtgtttag gaggtgtgtg gggcatggat 370980 ggggacccac cagagaaagc atgtggccct gggactccag gttgtgattt ccagttcatg 371040 ctgggatagg gcacctggat gggtgcccac aatgcaccgg ggcaggctat gtgactgcca 371100 gctttgcagc ggcatctggc atccgggcca gcctccttgg ttggccatga actggttggt 371160 ggccctggcc tgtgcccagt agctctgtcg taatcctggg gtcatgcgag ggagccggca 371220 tgggcagtgg aggtgctcgt gggacctgcg gtaggacaca gccaggtctt cttgcccgag 371280 cccagtgacc cacctgccct gtccttccag ggttcagtgg ttgagagtac agggtgactt 371340 gtgtctgtga caagccagtg ttctgcatgg atcccatcac gtggatccat ggacggcaag 371400 catccctgag ccgccacacc ccaccttctg cctccatgga ggggtgaggt tgtgtgtgga 371460 cgcctgtcct actcctgttt ccccaggtat tgagcctgga ggaagacttg aattggtccc 371520 aatggtccca ggccagcatc catcagctag gtgctgagcc cctggtgcac tgaagattgg 371580 gcacttcctg gcaccctggt gtgctgcacc gagctgtgat gagcacatcc gggtcctgct 371640 ggatgcatgc gccgggaagg acgtgccctg agttgggtcg atgatgagaa ccttatatta 371700 tcctgaagag aggtgatgac ttaaaaatca tgctcaatag gattacgctg aggcccagtc 371760 taggtgagag ttttggaaga ggatgctggg atcctgaggt cccctggtag agccaattgt 371820 attttgggct ggagacctgg aagccctgaa gggcatctgg gaggcccaac cctgtctctg 371880 tgctcctcca tgaggcagcc ctggctcccc atgtaggctt ggtgatggcc ttcctgttcc 371940 ctgggggtgg ggcacatggg tagctcctcc ctgaccccca ttctctcctg tgtctttcag 372000 tgagctcttc cccacaggtg ggccccctgg cattgactag catcggtgag tggatcctgc 372060 tggggtcgtg ggccgtgcac caggctgcat ggggtcacca agtattagcc ttcaggacag 372120 gagggtttcc tcagggagtc gaccttaatc ctcacctgtg gagagatggg tttgtcctct 372180 aggagggcag cttcctggga aatcagaccc aagacgatgc cttccctgaa gccctgcagg 372240 ggtgacggtg gtccagtctg gaaagggttc cttcagtctc atgcagggca gctcccagct 372300 gacacttggt gtgagagtct gtccttgagg actgcccagg acaaatgagt gggacaacag 372360 aggctcccgg ataccacagg gatcactcag gggctctccg tccctggaaa tgggtgggcg 372420 atcgggccca tggggtgggg ctgcggagat tcaaggatcg tgccctgctc atggccctga 372480 atgcaaatga ccctgttgag caatgggtca caccagtagc tcctttttga gcctggtggg 372540 tggcggctca gcttcaactg gttgggtcaa ggctgagcca tgactggtgc tttgtggtgc 372600 cgcaggccaa ccctgggact catgggcttt gggtcaaggg tgcagcccgc ctgctgctgg 372660 gggtcacccc ttcttcgagg tcagtggcgg gaagggtcac gtcccgaggt tggaaagccc 372720 cctcatgagg gacctgtcct gggaatttgt tgcccaggct gcttctgagc catgtggtca 372780 cttccgggtg gcggggtctt gggcccaagg aaaggagagg gcaccatgtg gctcctgatt 372840 ggctcagtgt ggcccagctc tgtgtttgac aggggtctgg ggtgtggatg aggacccacc 372900 agacaaagca cgtggccctg ggcccaggct gtgatttctg gtgcgtgctt ggagaaggat 372960 cctgggcagg cattctctcc aaacaggggc aggttgtggg actgccagat tggcagcagt 373020 gcctggcatc caggccagca tccttggttg gctgtgagct ggttggtgac cttggaccct 373080 gcccagggtt tccgttgtgg tccagagtca tgcagtgggg ccagtgtgag cagtggaggt 373140 gctccagggg cctgctgtat ggcacagcca gggcatctta cccaagccct cctgcactgg 373200 tctcctgcac tgagctgtgg tgagcccatc tgggttcctg tgatgcctgt gcggggaggg 373260 ggttgccctg ggttgggtcg atgatgagaa acttatattg tctgaagaga ggtgatgact 373320 taaaaatcat gctcaatagg attacgctga ggcccagcct aggtgagaat tttggaagag 373380 gatgctggga attatgagtt ccctggcaga accactgtat tttgggctgg agacctggag 373440 gctctgaggg catctggagg gtgcccaacc ctgtctctgc gctcctccgt gaggcagccc 373500 aggctcacta tgtgggcttg gtgttggcac tcctgttacc cgggggtggg gcattttggc 373560 atctcctttc tgagccccca atctcccctg tgtctttcag tgagctcttc tgcccagcag 373620 cctccctggc agtgaccagc ataggtgagt ggatcctgct ggggtaatgg cccatgagcc 373680 aggctgtgtg gggtcaccaa gcatcagcct tcagccataa gagtttcctc aggagctgac 373740 ccgaatgccc acctgggatg ggttctccag aagagtggct tccttggaaa tcatacccaa 373800 ggaagatacc ttccctgaag ccctgcaggg gttgcagtgg tccaggcagt aaagggtttt 373860 ctcaacctca tgcagggcag tgccccacta agactcagtg ctctggtcag gcctttagga 373920 tggccaggcc acatgagagg ggccacaagg gctctggggc accaaggggt tcttgcaggg 373980 gctcttcaac cttggagagg tgtgtgtaat tcagcccatg aggtcaggct gtggattttc 374040 aaggattgca ccaaacccat ggccctgaat gggacaaacc ctaataagtt atgggccatc 374100 ccagtggtgc ctctttgagc caagtgtggg gtggcactgt ttcctaaggg tgagtcaaga 374160 ctagctctgg ctggcacctg atggtggtgc aatcctgccc tgggattggt gggctttggg 374220 acatgggtac agcccatgtc ccattggggt caccccttca ttgtggacag gtggcgggaa 374280 gcatgtcctc ctgaggtggg aaggcctgct gtggaagacc ctgtctcaga aatttgctgt 374340 cttggctgct tctgagctat ggcgtcacct ctgtggtggc gggagtctcg ggtgaatgga 374400 tcctgctggg gtcatgggcc atgagccagg ccggggtggg gtccctgagc gtcacctttc 374460 gggtcatgag ggtttcctaa gggagccgac ctgaatcccc accagggatg aatggtttct 374520 ctgggaagca ggtttccttg gaaatcagtc ccaagaagga caccttccct gaaaccttgc 374580 aggggtaaca gaggtccagg caagagaggg ttctttcaac ccaacgcagt gcagatccta 374640 gctgagactt ggtgcacagg tgagtcctgg aggactgccc aggccacatg agggcatcca 374700 cagggtctcc gtggccagga gtcttatacg ggagccctct gtccccgagg cttgcagagg 374760 ggttgggtgt gggtgatctg gcttacggag tcaggccgtg aacattcaag ggtcgggaac 374820 cacccatggc cctgaatggg accgaccctg ttgagcaatg gccatcctgg tggtggcacc 374880 ttgagcctgg tgggggtggc gctgcctcag tggggttggg tcaaggctga gctctgcctg 374940 tcaccttgtg gttggccctg ggaatcatgg gctttgggcc aagggtgcag cctgcgtccc 375000 gcttgaggtc actcctacct gaagtggagt ggccggaagg gtggcatcct gtggtgggag 375060 acccacggtc aaggatcctg tgctggcaat ttgctgcgca gcctggttct gagtcatggg 375120 gtcacctcca gggtgacagg gtctttgtca aagggaagga gaggacatta tgtggcccct 375180 gattggccaa gcatggccca gctctgtgtt tgggaggtat gcggtgcctg aatggggacc 375240 caccagagaa ggcacatggc cctggggccc caggatggta tttctggtgt gagcttataa 375300 agggtgcatg gatgggtgca ttccatgccc agtggcgggt tatgtgactg ccaggtctgc 375360 agtggcacat ggggtccggg ccagcctcct tggtttgcca tgagctggtt ggtggcccag 375420 gccctgccta gtggtctcat tgcagcccag agtcatgtgg gggagctggc gtgggcagtc 375480 gaggtgctcc agggtcctac agtagggtgc agcctgggcg tcttgctgga atcccatgac 375540 ccacctgccc tatccttcca gggttgagtg gcagggaggg ccaagggttc ctcgtgtgca 375600 tgactgtcac tgttttacat ggatctcatc tcatgagtcc atggtgggag agcatgtgtg 375660 agccagcaca ccctacccac tttgccctat ggaggcacaa ggccctgttt ggacacctgt 375720 cccccacccc tccagatgct gaccctggag gaagaattgc actgggccca ctggccccgg 375780 gaaaatgtcc ctcagccagg tgcttagccc ctggtaatct gaagctcagg cccttcctga 375840 tgccctggtc tcctgcactg agctgtggtg agcacatctg ggtcccaatg gatgcatgca 375900 tgcgttgtgg ggtggtggtg tcctgggttg ggtcgatgat gagaacctta tatgttctga 375960 agagaggtga tgacttaaaa atcatgctca ataggattac gctgaggccc agcctaggtg 376020 agaattttgg aagaggatgc tgggatttct aggtccctgt catgggcact gtattttgga 376080 ctggagacct ccgggccctg aacagcatct cgggggggac tctaccctgt ctccacatta 376140 catgtgaggc agcccaggct ccctttgtgg gcttggtgtc tgcactctgg ttccctgtgg 376200 tagggcagct tgctgggtcc ttcctgagcc cctgttctcc ctttgtgtct tctgtctttc 376260 agtgagctct tcagcccagg tgggctccct gacactgatg cgcataggtg agtggattct 376320 gctggcatca tgggccatga gccaagctgc gtagggtcac caaaggtcac tctttaggcc 376380 acgtgggttt cctcagggag ccgacctgaa tccccaccag gttgggacag tttctccagg 376440 aggctggctt ccttgggaat cagacccaag acaatgcctt ccctgaagcc ttacaggggt 376500 aacagttgtc cagacaggaa agggtcccct cagtcccatt gaaggcagct cccagctgag 376560 actcagtgtg cgagtctggc ctcaaggatg gcccaggcca catgaaggag gccacagggg 376620 ctctggggtg ccacaggggt cacacgagag ctctctttcc ctggagtggg gtgctcgaat 376680 gagcccatgg ggtcaggctg cagagattca aggatcgcat cccaaccgtg gccctaaatg 376740 cgaccgacca tgttgagtaa tgggccatct cagtggggcc tctttgagcc tggtgggggg 376800 cggggctgtt tccctgggtt tgggtcaagg ctgagctctg gccagcgcct ggtgatgctg 376860 caggccagcc caggttcttg tgggcgttgg tccattcggc agccctgtcc tcctggaggt 376920 caccccttgc ctattggtga ttggctggat cctgaggtgg aaagacctgc tgttgatggt 376980 cctgtcccag gaatttacca cccaggctgc ttctgagcca tggggtcacc tccagggtgg 377040 cggagtcttg gggctaagaa aaaagaggac actatgtagc ccacggttgg ccaagggtgg 377100 cctgactctg tgtttgggac atgtgcgggg catggatagg gacccgccag agaaagcacg 377160 tggcccgggg actccaggct tcgatttcag gtgtggcttg caaatagcac ctaggcaggt 377220 gcccaccacg ccctggggca ggctatgcaa cttccatctc cacagtggcg catggcttct 377280 gggccattct ccttggttgg ccatgagctg attggttccc ctggcctgtg ccctgtggtc 377340 ccggagtggc tctgggatcg tgtggggcag ccagcatgga cagtggagat gctatcaagg 377400 ccttcagtag ggtgcagccc aggtttcttg cctgaaccca gtgacccacc taccctgtgt 377460 tttcagggtt tgctgacagg gaaggccaaa cgtgccccac gtccatgcta ggtcagtgtt 377520 cctcatggac cccatcacat gggtatccct taccccttcc ccacatggaa gtatgaggct 377580 ctgtttggac acatgtcctc ttcctgtccc cccagatggt gagcctggag gaagacttgc 377640 attgggccca atggacccag gccagtggcc atcagccagg tgcccaccct ggtgtgctga 377700 agcgcgggac ctacctgttg tcctggtttc ctacactgag ctgaggtgag cacatctggg 377760 tccctctgga tgcatgcatg gggcgggggg tgccctggtt tgggtcaatg atgagaacct 377820 tatattatcc tgaagagagg tgatgactta aaaatcatgc tcaataggat tacgctgagg 377880 cccagcctag gtgagaattt ggaagaggat gctgggatcc caaagtccca gtaggggact 377940 ttatttattt attttgggct ggagccctgg aggccctgaa gggcatctgg ggggcccagc 378000 cctgtctctg tgctcctccg tgaggcagcc cagcctccct gtgtgggctt gctgttggtg 378060 gtccagttcc ttggggcggg gcacgtggac agctcctcct tgagcccccc tgctccactt 378120 gtgtctttca gtgagctctt caacccaggc ggggcaccct ggcattcacc agcataggtg 378180 agtggatcct gctgccatcg tgggccatgg gccaggctgg gtagagtcac tgagggtcag 378240 ccttcgggac aggagagttt cctcagggag cgaacctgaa tccccaccag ggagggatag 378300 gttggtcctc cagaagggtg gcttcctgag aaatcggacc caagggggac gccttccctg 378360 gagccctgca gtgatgacgg tggtccaggc aggagagggt tccttcagtc tcacacatag 378420 tagctcccag ctgagtctag gtgttcgagt ctggccttga ggactgccca ggccacctga 378480 ggggccaaca gggactctgg gacaccatgg gggtcacata ggagctctcc attcatggag 378540 aaagatggat gatagggccc atggagtcga gctgtggaga tttaaggatt gcgcccaatg 378600 tatggccctg aatgggacag accctgttga gtaatgagcc attctatggg cctcatcgag 378660 ccttgagcgg ggcggtgctg tttccctatg tttgagtcaa ggctggactc tggccggtgc 378720 ctggtggtgc tgaggtctgg ccatggactc gttggctttg ggccaagggg tcagcctgct 378780 ccccctggaa gtcccccctt ccccgtggct ggaagtcatc ccttcccaag gggcaagtgt 378840 cgggaatggt tgcctcctga ggttgcaagg cctgctatct agggtcttgt ctttggaata 378900 tgctgcccat gctgcttctg agtcatgggg tcacctccag ggtagcggat cttgggccca 378960 gggacagaag atgccgtgtg tcccctgatt agctgattgt agccctgctc tgtgttcagg 379020 aggtgtgtgg ggcatggatg cagacccacc agagaaaact gtggccctta gaccccaggt 379080 tgcaatttcc attatgtgct gggatagggc atctgggtgg gcacccacta tgcacagaga 379140 taggctatgt gactgccagg gctgtagcgg catctgacat ctaggccagc ttccttggtt 379200 tcctgcgaat gagttggtgg ccctggcctg tgcctagtag ttctggggtg accccgggtc 379260 gtgtggggga gccagcaggg gcccagtgac cagcctgccc tgtccttcca gagttctgtg 379320 gctaagagag cactgggtac cctgtgtccg tgatgggcca gtgttccgca tgcaaacgat 379380 cacatgggtc catggagggc aagcatactt gaactgccac accccacctt ctgctcacat 379440 acaggagtga ggttgtgttt ggacagctgt cctactcctg ttcccctaga ctgtgaaatg 379500 ggaggaagaa ttgtgttggg cccaatggcc ctgggccagt atccgtcagc ctggtgtcca 379560 gcccctggtg tgctgaagct catgcccttc ctggtgccct agtttcctgc actgagcttg 379620 gtgagcccat ttgggtactg ctggatgcat gggtggggag ggaggtgccc tgggttgggt 379680 cgatgatgag aaccttatat tgtcctgaag agaggtgatg acttaaaaat cattctcaaa 379740 aggattatgc tgaggcccac cctaggtgac aattttggaa gaggacactg gaaatcaatg 379800 aggtccctgg cagggccact ataatttggg gtggagacct ggaagccctg cagggcacct 379860 cgtgggggcc caaccctgtc tcttcactcc cctgtgaggc agcccaagct ccctctgtag 379920 gcttggtgtc ggcactctgc tttcctggag gcggggcatt ttggctgctc cttcctgagc 379980 ccctgttctc ccctgtgtct ttcagtgagc tcttttgccc agaagactcc ctggcattga 380040 tcggcatagg tgagtgtctc ctgcttgggt catgggccat gagccagacc atagggttgc 380100 cgagggtcag catttgagcc atgagggttt cctcaggagg cgacctgaat ccccacctgg 380160 gatgggttct ccaggagggc agcttccttg tgaatctgag ccaagtaaga tgccttctct 380220 gaagccctgc aggggtgcca gttgtgcagg caagaaaggg ttccctcagc cccaggcagg 380280 gcagcgccca gcagagactc ggtggttggg ttaggcctct aggatgacca ggccacatga 380340 ggggggccac aagggctctg gggcacaaca ggggcttcgc agggtctctg cgaccccaaa 380400 gagtggtggg cgattcggcc catgggatcg ggccccagat tcaaagatca caccacaccc 380460 atggccctga atggaaccga ccctgttaag cattggggca tcccaggggt gccactttga 380520 acctggtgtg gggtgccgct gtttgcctga ggttgggtcg agactagctc cggccagcac 380580 ctgatggtgg tgcagtccgg ccctgagatt agtgggctgt gggcccaggg tgcagcctgt 380640 gtcccgctgg gggtcacctc ttccttgtgg gcgagtggtg gaagggcatc ctcctgaagt 380700 gggaaggccc gctgtggaag gaactgtcct ggaaatttgc catccaggct gcttctgagc 380760 catggggtcg cctccagagt ggcagggtct tgggcccaag gaaaggagag gacactgtgt 380820 ttccctcaat tagctgagtg tggccctgct ctctgtgtgg gaggtgttgt gtggggcatg 380880 gatagggacc caccagagac aacacatggc cctcgggccc caggctgcaa tttctcagtg 380940 catgcttgga gacggtcctg ggcctcctcc atgcccaggg tcaggctgtg caactgtcag 381000 gttagcggcg gcatgtggtg tctgggcctg tctacttcgt tgtccgtgag ctgctggtgg 381060 ccctagccct ttcccagggg ttcaggtgca gccctggggt tgtgtgggac agccagtgtg 381120 ggcagtggag ctgctctgga ggcctgcttt agggtgcagc ctgggtgtct tgcccgagtg 381180 tagtgacccg cctgccgtgt cctcacgggg ttccctagca ggaagggcca agggtcccct 381240 gtgtctgtga cacgtgagtg tttcccatgg gtcccatcaa atgggtccac ggagggagag 381300 catgagtgaa ctggtacccc ccacccccac cctcttcccc acctggaggc atgagcccct 381360 ggttggacat atgtcctcct cctgtacccc cagatggcag cgctggagga ggacttgtac 381420 tggggccgct ggccccacat cagtgtccgt catcccggcg tccagcccct ggtgtgctga 381480 agctcaggcc cttccttgtg ccctagtctc ctgcactgag cttggtgagc ccattcggat 381540 actgctggat gcatgggtcg ggagggaggt gccctgggtt gggtcgatga tgagaacctt 381600 atattgtcct gaagagaggt gatgacttaa aaatcattct caaaaggatt atgctgaggc 381660 ccggcctagg ttagaatttt ggaagaggat gctgggatcc tgaggtcccc aggagagccc 381720 ctttattttt ggctggagac ctggaggccc tgaagggtat ctggggggcc cagccctgtc 381780 cctatactcc tctgtgaggc agcccaggct ctctgtgtgg gcttggtgtt ggcactctgg 381840 ttttctgggg gcggttcagg ttgctggttc cttctgaacc attgttctcc ccttgattct 381900 ttcagtgagc tcttctgctc aggcgggtcc cctggcattg accagcatag gtaagtggat 381960 cctgctgggt tcatgggcca tgagccagac cacatggagt gactgagggt cagccttcag 382020 gacaggaaga tttcctcggg gagccaacct gaatccccac cgtggaggga tgtgttagtc 382080 ctccaggagg gtggcttcct agggaatctg accccaggag gacacctttg ctgaagccct 382140 gcaggggtga tggtggtcca ggctggaaag ttttccttca gtctcatgtg gggcagctcc 382200 ctgctgacat tccgtgcctg cgtctgacct tgaggactgc ccgggccaca tgagtggggc 382260 aacaagggct ccagggtgcc acggggatta tgagtggggc tctccatccc cggagagagg 382320 tgggcaatca ggcccatgtg gtcaggcttg tagggttcgg tggtggggag agccaaggtt 382380 tccctgggtc cattaccgtc actgtttcac ctggatccca tcacatgggt ccatggaggg 382440 agagcatgtg tgaacaggca ccccttgctc cctttcccac atgagcccct ggttggacat 382500 atgtcctcct cctgtccccc cagatggtgg ccctggagga ggacttgtat tggggccact 382560 ggccccacgt cagtgttcgt cagcctggca tccagcccct ggtgtgctga agctcaggcc 382620 cttcctgttg ccctagtctc ctgcactgag cttggtgagt ccattcgggg actgctggat 382680 gcatgggcgg gtagggaggt gccctgggtt gggtcgatga tgagaacctt atattgtcct 382740 gaagagaggt gatgacttaa aaatcattct caaaaggatt atgctgaggc ccggcctagg 382800 ttagaatttt ggaagaggat tctcggatcc tgagatcccc agccaggcca ctgaattttt 382860 ggctggagtc cttgaggccc tgaagggtgt ctgagggctg ctgaaacctg tctctgtgct 382920 tgtccgtgag gcaacccaca ttcgctgtgt ggacttggtg ttggccttcc cgttctccgg 382980 ggatgggaca tactgtcagc ttgtccctga gtacccgttc tcccctgtgt ctttcagtga 383040 gctcttctgc ccaggtggtc cccctggtct tgatgggcat aggtgagtac atcctgctgg 383100 tgtcctggtc catgagccag ggtgcgtacg gttgccggag gtcaccttta ggccatgtgg 383160 gtttcctcag ggagctgacc tgaatcccca ctgggaggga tggtttctcc aggaggatgt 383220 cttccataga aactggttcc aagaaggatg ccttccctga agctgtgcag gggtgacgat 383280 ggtccaggca ggaaagggtc cattcaaccc aatgcagtac agcttctagc tgagactcgg 383340 tgcacgggtg agggcttgag gactcccagg caacatgagg ggttccacag gatctccgga 383400 ggccacaggt gttaagcagg aactctccat ccttgaggct tgctgggggt ggcgggatgg 383460 cagcagggtg tgggtgatcg agtttatgga ttcaggccaa gattcaaggg tcaggcccca 383520 cccattgccc tgatgggacc aaccctgttg tgcaatgggc tgtcccactg gtgcctcctt 383580 gagcctggtg tgggcagcgt ggcttcaatg gggttgggtc aaggctgagc tctggcccgc 383640 acctggtggt tggccctggg aattgtggac tttgggccaa gggtgcagcc cgcctgcctc 383700 tggaggtcat cctacccaga ggtggagtgg ccggaagggt ggcaggcatc ctgtggtgaa 383760 aggcccactg ttgagggtcc tgtcccacca atttgctgtt caggctgctt ctaagccatg 383820 ggttcacctc cagagaggcg ggatcttgag cccagggaaa ggagagggca tcatgtgtcc 383880 cctgattggc tgagaatggg gagagtgttt gggtggtatg tggtgcatga atggggaccc 383940 accagagaag gcgcgtggcc ctgggcccca ggatgcaatt tccggcgtgc ttatagaggg 384000 cgtctgagtg gacactctcc atgcccaggc gcaggctatg tgactgccag gtctgcagca 384060 gtttgtggca tctgggctag cctccttgat tgcttatgag ctggttgata gccctggcct 384120 gtgccgaggg gtcctggtgc ggccctgggg ttgttcaggg gaagccggca tgggcagtgg 384180 aggtgctctt ggggcctgca gtagggcaca gcccaggtgt tcttgcttga gcgcagtgaa 384240 ccacctgccc tttccttcca gggttcggta gcagggaggg ccaagggtcc cccacgtcca 384300 tgacaggtca gcgttcctcc tggatcccat cacatgggta catgcaggga gagcatgtgt 384360 gagccggcac tccccactct cttccccgca ttgcagggtg aggccctgtt tggacccatc 384420 ttccagctat ctcaccagat ggtgagccca gaggaagacc ccgtggctct gggccagtgt 384480 gcgtcagcca ggtccccagc ccccagtgtg ctgaagctca ggcccttccc aacgccctgg 384540 tctcctgcac tgaggtgtgg tgagcacaac caggtcccac tggatgcatg cacagggagg 384600 gatgtgccct aggttgggtc gatgatgaga accttatatt gtcctgaaga gaggtgatga 384660 cttaaaaatc atgctcaata ggattatgct gaggcccagt ctaggttaaa attctggaag 384720 aggatgctgg gatcccaagt tcacaggcag ggccactgta ttttggacta gagaactcga 384780 ggccctaaag ggcatcttga gggggtccaa cctgtctctg tgctcctcca tgaggcagcc 384840 ctggctccct gtgtggcctt ggtgttggtg ctctggttcc caggcgtggc atgtgggcac 384900 ctccttccag agcccccatt ctcccctgtc tctttcagtg agctcttccg cccatttggg 384960 ccctctgaca ttgaccggca taggtgagtg gatcctcttt gggtcatggg tcatgagcga 385020 ggcaaagtgg ggtcaccatg catctgcctt cgggccatga gagtttccta aaagtgtgga 385080 cctgaattcc caccggggat gagttatcca gaagggccac ttccttggga atcggaccca 385140 agaaggacgc ctgtcctgaa gcccagcagg ggtggtggtg gtccaggcag gaaagggttc 385200 attcagcacc aagcaggcag ctcccatctg agacttggtg catcggtcag gccttgagga 385260 ctgcccagga cacatgaggt ggccacaggg gctccggggc actacagggg gtctgcagag 385320 aggggtaggc gattgggtcc gtgggggtca tgccgcggag tttcaaggac acccatggcc 385380 ctgaatggga ctgaccctgt tgagtaatgg gccatcccaa tggcacctcc ttgagtctgg 385440 cggtgggtgg tgctgtttcc ctggggctag gtcaaggctg agctctggct agtgcctgtg 385500 gtgctgcagg ctggccctag aactcatggg ctttgggcca tggggacagc ttgtgtcatg 385560 cttggggtca ccccttcccg gaggttgaat ggcgggagtg gtggcttcct aaggtgggaa 385620 gtcctgctat tgagcaacct gtcctgggaa tttgccaccc aggctgcttc tgagacatga 385680 ggtcacctcc agagtggcag catcttgggt ccaaggaaag aggagcataa catgtgtccc 385740 cagattggtt gagtgtggcc tagctctgtg tttgggaggt gtgcagggtg tggatgggga 385800 tgtatcaaag aaagtacata gccctggagc cccaggctgt gatttccagt gtgtgcttgg 385860 agaggggcag gagcaggctc tcgactgcca ggtctgcagc agcgcgtggc atccgggcaa 385920 gccttctggt tggccatgtg ctggttggtg gccctggcct gtgcccagtg gtctcagggt 385980 agacctggca ttgtgcaggg cagccagcag ggcagtggag gtgctctcag gacctgcagt 386040 agggcgcagc ctggactttt tgtgtgagac cagtgaccca cctgcactgt ccttccaggg 386100 ttgggtggct gggagggcca agggtggtcc atgtttgtct ccgtgacaca tcagtgctct 386160 gcatggatcc tatcacatgg atatccccta cccaccttcc ccacatggaa gcatgaggcc 386220 ttacttggac atgtgtcctc ctgtcctaga tggtgagctc ggaggaagac ttgcattggg 386280 cccaatggag ctgggccagt ttctgtcagc caggtcccca gctcctgatg cactgaagct 386340 caggcccttc ctggagccct ggtctcctgc cctgagctgt ggtgagccca tctgggtccc 386400 actggatgca tgcatgggag ggggttgccc tcggttgggt cgatgatgag aaccttatat 386460 tttctgaaga gaggtgatga cttaaaaatc atgctcaata ggattacgct gaggcccaac 386520 ctaggggaga attttggaag aggacgctgg gatcctgagg tccgtggcag ggccaccgta 386580 ttttgggctg gagacctcaa ggccctgaag ggcatcttgg cagcccccag ccctgtctct 386640 gcactcctcc gtgaggcagc ccaggctccc tgtgtgggct tggtgtcaga gtcccattcc 386700 ccaggggcgg ggcaggttgg cggctcctcc ctgagtcccc tttctccctt gtgtctttga 386760 gtgacttctt ctgcccaggt gggccccctg gcgttgacca gcataggtga gtggaacctg 386820 ctggtgtcat gggccatgag ccaggccatg tggggactcc aggtcagcct tcaggacagg 386880 agagtttcct cagggagcag gggaatcccc actggggagg gatgggttct cccagagggc 386940 cactttcttt tgaatcggac ccatggagga catcttctct gaagacctgc agaagtgatg 387000 atgtttcaag cagcaaaggg ttttttcagc ccctgcaggg caggcagctc ccagatgaga 387060 ttctgtgcat gggtcaggcc tcaagaactg cccaggccac atgcggggtg ccacacaggc 387120 tgtgaggcac cacaggggtc atgcaggagc tctcggtctt caggcttgtt gtgggggtgg 387180 tgacagagtg atcaggccca cagggtcagg ctgcagtgtt tcaaggatcg cgcccacctg 387240 tggccctgaa tgggaccgat gctgttgagc aatgagccat cccagtggct ccacattgag 387300 cctggtgggg gcgccactgt ttcagtgggg atgggtgaag cttgagctct ggccagcacc 387360 tgatggtgtt gcaggctggc ccagggactt gtgggctttg ggccaggtcg gcagcctgag 387420 ttctgctggg ggtcacatct ttcctgagtt tcagtgtcag gatgcatggc ctccttaggt 387480 gggaaggcct gctgtggagg gtcctgtcct gggaatttgc tgcccaggct gcttctgagc 387540 catggcgtca cctccaggtg gtggggtctt gggcccaagg agcagagaag acaccatgtg 387600 gcccctgatt ggtcgagtat ggcctggctc tgagtttggg aggtgtgcag ggcatggatg 387660 gggacccacc agagaaagca cgggccaatg aagccccagg ctgcgatttc tgatgcgcac 387720 ttggagaggg cgcctggttg ggcgcccacc atgcccaagg gtaggctatg caactaccag 387780 gtctgcggca gtgcctggca tcaggaccag cctcctttgt tggctgtgag ctggttggtg 387840 gccctagccc gtgtccagtg atctctgtgc agccctgggg tcatgtggag cagccagtgt 387900 aggcagggga ggttatcttg aggtgtgcag taggcacatc ccaggcatct tgcccgagcc 387960 cagtgacctc cctgccctgt ccttccaggg ttcggtggcg gggaggccca agggtaccct 388020 gtgtccatga caggtcagta tttcatgtga atcccatcac atgggccctc ctcctgtccc 388080 cccagatggt gagcctggag gaagacttgc actgggcctt ctgtgcgccg gccagaggcc 388140 atcaaccagg tgcccaggtc cttttgtact gaagcttggg cccttcctgg caccctggtc 388200 tccttcatgg agctggtgag cccatccggg ttcttctgga tgtatgcatg gggagcgggg 388260 tgcactgggt tgggtcaatg atgagaacct tatattgtcc tgaagagagg tgatgactta 388320 aaaatcatgc tcaataggat tacgctgagt cccagcctag gtgacaattt tggaagtgga 388380 cactgagaat cacaaggacc ctggcagggc cactgtattt tgggctggag acctggaggc 388440 cctcaagggc ctctcacagg gacccaaccc tgtctctgca ctcctccgtg aagcacagca 388500 ggctccctgt gcggacttgg tgttggcact gtttcccagg ggcagggcac attggtggct 388560 tttccctgag tccccattct tgccttgtgt ctttcagtga gctcttcagc tcagaagggc 388620 cccttcacct tgattagcct aggtgagtgc atcctgctgg tgtcatgggc catgagtcag 388680 gccgcgtggg gtcaccaagg gtcagtcttt aggacaggag ggtttcctca gggagccaac 388740 ctgtatttcc accggggagg gatggtttct acaggagggc ggcttccttg ggaactggac 388800 ccaagatgtt gccttcctga agccctgcag ggatgacagt ggtccaggca gcaaagactt 388860 ccttcagccc cgtgcaggag agctcccagc tgagactcag tgcatgtgtc aggcctcgag 388920 gattgccgag gccacatgat gggggccaca gggcctccgg ggcaccacgg gggtcatgca 388980 agagttctct ttccctggag aggggtgctt gaatgagcct atgggattgg gccgtggaga 389040 ttcaaggatt gtacccaact atgtcccaaa atgggactga ccctgttgag ctatggacca 389100 tcccatggtg cctctttgag cttggtgggg ggcagtgctg tttccctggg tttgggtcaa 389160 ggctgagctc tggccagtgc ctggtgaggc tgtgggccgg acctgggact cgtgagcttt 389220 aggccaagtc gacagcttgt gtcctgctgg aggtcacccc ttccccatgg gtgagtggct 389280 ggaagagtgg aatgtgcggt gggaaggccc gctgttgatg gtcctatcct gagaatttgc 389340 tgcccagact ctctgtgcca tggggtcatg tccagggtgg cagggtcttg ggcctaggga 389400 aaggaaagga caccatgtgg cccaggattg gccaagggtg gcccggatct gtgtttggga 389460 catgtgtggg gcatggatgg ggacccacca gagaaagcac atggccctgg tactccaggc 389520 tgtgatttca ggtgtggctt ggagagagtg cctgggcagg tgcccaccat gcccagcggc 389580 aggctatgca acttccatgt ccacggtggc acatggcttc tgggccaggc tcctcggttg 389640 gccatgagca tgtcggtgac cctgtcccat gctcagtggt cctggggcag ccctgggatc 389700 gtgtgaagga gaagtcagag ggggcactgg atgtgccctc aaggtctgca atagcatgaa 389760 gaccaggggt cttgcccaag cccagtgatc cacctgccct gttttttcag ggtttggtga 389820 tggggagggc cgagagtgcc ctgtatccgt gacaggtcag tgttccacat ggatcccatc 389880 acatgggtat cccttacccc attccccacc tggaggtatg aggccctgtt tggacacatg 389940 tcctcctcct gtccatccag atggtgagcc tgaaggaaga cttgcatcag gaccaatgga 390000 ccctggcaag tgtccgtcag ccaggtgctc agcccctggt gcactgaagc tcaggccctt 390060 cctggcccct tgatctcctg cactgagctg tggtgagcac atccgggtcc cgctggatgt 390120 atgtgtgggc agggggggtg ccctgggttg ggtcaatgat gagaacccta tattgtgttg 390180 aagagaggtg atgacttaaa attaccatgc tcaatgatta cgctgaggcc caacctaggt 390240 gagaaatttg gaggaggatg ctgggatccc gagatttccg gcagggccac tgtattttgg 390300 gctggagccc tggaggccct gaaaggtatc tggaggaggc ccaactctgt ctctgcactc 390360 ctctgtgagg cagcccaggc tccctgtgcg ggcttggtgt tggcctttct gttccccagt 390420 gaagtggcac gtgggtggct cctccctgag ccccagttct ccccttgtgt ctttcagtga 390480 gctcttctgc caaggggggg cctcctggca ttgaccaaca taggtgagtg gatcctgctg 390540 gcatcatggg catgggttca ctgagggtca gacttcaggc catgagggtt tcctcaggga 390600 gctgacccca attcccatca gggagggatg gtttctccag gagggcggct tccttgggaa 390660 tcttacctga ggaggatgcc ttccctgaag atctgcagga atgacaatgg tccagatagc 390720 aaagggttcc ttcagcccca tgcaggacat cgcccagttg agacttggtg tgcaggtcag 390780 gccttgagga ctgcccaggc cacatgaggc gggccagaag ggctccaggg tgccacgggt 390840 ttcacttggg agctctcggt ccccgggcat gttcctgggg ggggtggtga tggggtcggg 390900 ccatggaggt tcaaggatct catcccacct gtgaccctga atggggctga tcctgttgaa 390960 caatgggcca tcccagtggc acgtattgag cctggtcagg ggtggtgcag tttcaatggg 391020 gttgggtcaa ggttgagatc tggccagctc ctggtggtgc ttcaggccag tcctgtgacc 391080 catgggcttt gggctaaggg ggcatcccat gtcccatggg ggtcacctgt tctccatgtt 391140 tgagtggcag taacagtggc attctgaggt gggaaggtcc actgtctagg gtgttgtacc 391200 gggaatttgc caccccgcct tcttagccaa ggggtcacct ccagggtctc gggatcttgg 391260 gcccaaggaa acgagaagat accatgtggc ccttgattgg ccgagtgtgg cccagctctg 391320 tgtttgagag gtgtgggata tgaatggggt cccaccagtg aaagctcatg gcccaggtcc 391380 ccaggctgtg atttttagtg cacacttggg gagggctcct cagtgggtgc ccaccacgcc 391440 cagaggcagg ctatgtgact gccaggtctg caacggtgca tagcttccag gctaccctcc 391500 ttggttggct gggagcgggt tggtggccat ggcccatgcc cagtggtcac agggcaaccc 391560 tgggatcatg caggggagct ggtgagggca gtggaggtgc tctccggaac ggaagtatgg 391620 ctcagcccag gtatctggcc caaacccaat gaccagcctg ccttgtttct cagggtttgg 391680 tgatggggag ggccaagggt gccctgcatc tgtgatgggt ctgttccaca tagaacccat 391740 tacaggggat cccttctcca catggagatg tgaggcccta tttggacaca tatcctcctc 391800 ctgtcccccc agatggtgag cctggaggaa gatttgcatt gggcccaatg gccctgggcc 391860 agtgtctgtc agccagtttc ccagcccctg gtgcactgaa gctcaggcct ttcctggcat 391920 cctggcctcc tgcactgagc tgtggtgagt atatcatggt cctgctggat gcatgtgcag 391980 ggagggaagg tgccttgggt tcagtcagtg tcgagaacct tatattgttc tgaagagagg 392040 tggtgactta aaaatcatgc tcaataggat tacgctgagg cccagcctag ttgagaattt 392100 tggaagggga cagtaggatc ccgaagtccc tggcagggcc cttatatttt aggctggaga 392160 cttcaaggcc ctgaagggca cctggaggtg gctcaacctg tctctgtgct cctccatgag 392220 gcagtccagg ctccctctgt gggctttctg ttggcactct ggttccctgg gccagggaac 392280 gttggtggct cctccctgag cccctgttct ccccttgtgt ctttcagtga gtgcttctgc 392340 ccaggcaggc cacttggcat tgaccggtat aggtgagtgg atcctgctgg ggtcatgggt 392400 catgagcaag gccacatggg tcgccgaggg tcagccttac agccataagg gttttctcag 392460 ggagcccacc tgaattccca ccggggaggc ataggttctc caggagggcg gcgttttggg 392520 gaatcagacc caagggggac accttccctg aagccctgca agggtgatgg tggtccaggc 392580 aggaaagggt ttttttcagc cccacacaag gcagctccta gctgagaatc ggtgcttggg 392640 tcagacctca aggattgccc aggccacatg agggcgactg agagcctccg gggcaccaca 392700 ggggtcacgt gggagctctc ggtgcctggc gtgtgatgca caaatggacc tcttgggttt 392760 gttcatggag attcaaggat cgcaccccac catgcccctg aatgggatgg tccctcttga 392820 gaaatgggcc atcccagtgg gtctcctgga gcctggttgg ggggtggcat tgtttccctg 392880 gggttgggtg aaggcagagt tctggccggc acctggtggt gctgcaggtc agcactggga 392940 cccgtgggcg ttgggccaaa ggagagcccg aatcccactg ggggtcaccc tttttccaac 393000 atcaaatgtc tggaagggtg gcctcctgag gtgggaagtc ctgctgttga gggacatgtc 393060 ctgggaattt gtcactcaag cttcttctga gctttggtgt cacatccagg gtggcagggt 393120 cttgggtcca agcaaagcag agggcaccat gtgtctcctg attggccaag tgttgctggc 393180 tctgtgtggg aggtgtgcag agtatggatg gggacccacg agagaaagca cgtagcactg 393240 caactccagg ctatgatttc tgttgcatgc ttggagaggg tgcctggaca agcgtgccat 393300 gcccaggggc aggctgggca actaccaggt cttcagcgga gtgtgacatc tgggccagcc 393360 tccttggttg gccgtgacct ggttggtggc ccggctctgt gcctactggc cccagggcag 393420 ccctgggatc atgcagggga gccattttga acagtggagg tgctcttggg gcctgtagta 393480 tggcacagcc taggtgtttt gctcaagccc agtgacccac ctgccctgtc ctctccggga 393540 tcggtggaag ggagggccaa aggtgctccg tgtacttgat gagtcagtat ttcacattga 393600 actcatcaca tgtgtccatg gagggtgagc aagggtgaga tggcactgct gacccccttc 393660 cccacgtaga ggtcagtttg gacacttgtc ttcctcctgt ctccccacat ggcgacccca 393720 gaggaaaact tgtgttgggc ccgctgtcac tgggccaatg tcagtcagcc aggtgcccag 393780 cccctggtgc gctgaagctt gggcccttct ggcacccttg gctcctgcac tgagctgtgg 393840 tgagcccatc tgggtcctgc tggatgcatg tgcagggagg gggatacctg ggttaggtcg 393900 attatgagaa ccttatattg tcctgaagag aggtgatgac ttaaaaatca tgcccaatag 393960 gattacgctg aggcccagcc taggtgagag ttttggaaga ggatgctggg attctgaggt 394020 ccctgacaga gtaaatgtat tttgggctgg agaccttgag gccctgaagg gcatctggtg 394080 ggcccacccc tatctctgtg ctcctccgtg aggcagccca ggctccctgt gctggcttgg 394140 tatctgggct ccggatccct ggttatgggg catgttggag tctccttcct gagtccccgt 394200 tctcccctgt gtcttttggt gagctcttct gcccaagtgg tccccgcggc cttgagcggc 394260 ataggtgagt gcatcctgtt tcggtcatgg gccatgagtg atgcagcatg gggtcctcga 394320 cattcagcct tcgggccact agggttttct caggctgcca acctactccc caccagggag 394380 caatggtttc tccaggaggg ccacttcctt gggaatctga cccaaggagc acatctttcc 394440 tgaagccctg caggggtgac agtggtccag gcagcaaagg gttccttcag cccaatgtag 394500 ggcagctccc agctgaaact cggtggacag ctcaggcctg gagtactgtc cagggcacat 394560 ggggaggagg ggcacaggga atgtggcgca ccctagaggt tacactggag ttctctctcc 394620 ctggagaggg gtgagtgatt gggcccacac agtcaggctg tgaagattca aggaatgctc 394680 cacacccatg gccttgaatg ggaccaaccc tgttgagcag tgggccatct tatggtacct 394740 ccttgagtct ggtgagggat ggcactgttt cagtgaggtt gggtcaagac tgagctctgg 394800 ctggcacctg gtgctgctgc aggccctggg acttgggggc cttcagtcaa gggggcagct 394860 ctgatcctgc tggggacaaa ccttccttga ggtccagtgg tgaagagtgt cctcctaagg 394920 tgggaaggcc tgctgtcaag ggaatttgcc acccaggctg cttctgagcc ttggggtcac 394980 ctcagggtgg cagggtcttg tgcccaagga aaggagaaga caccatctgg ttcctgattg 395040 gctgagtgta gccgggctct gtgtgtcgga gttgggcagg gcatggatgg ggacccacca 395100 gagaaagtgt ggcccagggg ccccccaggc ttggagaggg caccagggcc ggtgcccaca 395160 atgctcaggt gctggctctg ggagggccag gtctgcagcg gcttttggca tctggccaac 395220 caccttggtt ggccaggagc tggttgatgg ccctgtcctg tgtcctgtgc cctgtgccct 395280 gtgtccctgg tatggccctg gggtcatgtg tgggagctgg cctgagcagt ggaggtgctc 395340 ttggggcctg cagtagggta cagcctaggc atcttgcctg agccagcact gtcttttgct 395400 ttccctgtct ttccagggtt tggtggcaga gagggcaaag gatgccccac atctgtgttg 395460 ggtcagtgtt cagcatggat cccatcacat gggtatccct tagccccttc cctgcattga 395520 tatgtgaggc cctggttgga cacatgtcct ccttctgtcc ctctagatgg tgagcctgga 395580 ggaagatgtg tgggacccgc aggccgaggg ccagtgtctc tcagccaggt gctcagcccc 395640 cagtgggctg aaactctgac ccttcctggc accctgctct cctgcactgt gctgtggtga 395700 gcacatccgg gttccactgg atgtttgtgc agggaggggg ttccctgggt tgggtcaatg 395760 atgagaacag ggccacatga ggggggccag aggggctaca gagtgccatg gggtaacaag 395820 ggagctcttg gtccctggag tgtggtgtgt gaatgggccc atggggttgg gtagcagaga 395880 ttcaaggatc ctgctctacc catggccctg aatgtgacca tcgctgttga gcaatgggcc 395940 atcccagtgg gtctcctggg gcctggttgg ggggcggagt tgtttccctg ggattgggtc 396000 aaggttgact ctggctggca cctggtggtg ttgcaggtca gccctgggac tcatgggctt 396060 tgggccaggg acagcccgca tcccgctggg ggtcacccaa gtgttgtgaa gggtggcctc 396120 ctgagttggg aaggcccgct attgaggcat ctgtactggg aatttgttgc tcacgctgca 396180 tgggagccat ggtatcacct ccagggtggc agtcttggga ccaagcaaag gagggggcag 396240 catgagactc cggattggct atgtgtgact ggctatgtgt cttggaggta tgtggagtat 396300 ggatggggac ccaccagaga aaacaagtga ccctgaggcc ccatgctgtc ttttctggtg 396360 cctgcatgga gagggtgcct gtacgcatgc ccaccatgcc caggggcagg ctgtgccact 396420 gtcaggtctg cagtagcatg tggcatctgg gccagcctcc ttggttggct gtgacctggc 396480 tggtggcccg gacctctgcc cagtggtccc agggcagccc tagggtcatg cggaggagca 396540 gttttggcca gtggaggtgc ccttgggtcc tgcagtcgtg cataccctgg gcgttttgcc 396600 tgagcccagt gacctacctg ccttgtcctt cccgggttcg gtggcaggga gagacacttg 396660 cataggtgat gagtcagtat ttcgcatgga tctcatcaca tgtgtccatg gagggggagc 396720 aagcgtgagc tggcacccaa cacccctttc tccacatgga gggtggtcac atgttctcca 396780 cctgttcccc tagatggtga gacttctgtt gggcttgctt ttcctgggcc agtgtccatc 396840 agccaggtgc tcagccatcg gtgcgctgaa gctccagccc ttcctggtgc cctgatctcc 396900 tgcactgagc tgtgatgagt acatccgggt tccactggat gcatgtgcgg gaaggggggt 396960 gccctgggtt gggtcagtga tgagaacctt atattgtcct gaagagaggt gatgacttaa 397020 aaatcatgct caataggatt acgctgaggc ccagcctggg ggagaatttt ggaaaaggat 397080 gctgggatcc cagggtcccc aacagggcca ctgtattttg gacctgggac ctggtggctc 397140 tgaagggcat ctggaggtgg cccaacctgt ctctgcactc tagtttccct gtgtgggctt 397200 ggtgtcggtg ctccagttcc ctgggggcag ggaatgttga tggctccttc ctgagtccct 397260 gttctcgcct ttgtctttca gtgagctctt tcacctagga gggccccttg gcattgactg 397320 gcataggtga gtggatcctg ctggtgttat ggatcatgag ccagaccata tggggtcccc 397380 aaggatcagc ctttgggcca caagggtttt ctcagggagc tgacctgaat ttccacctga 397440 gacggaaagg ttctcctgga aggcaggctt tttggaatcg gacccaagga ggacaccttc 397500 tctgaagccc tgaaggggtg atggtggtcc aggcaggaaa gggttccttc tgcctaacat 397560 aggacagtgc ctagttgaga ctcggtgctg cagtaaggcc ttgaggactg cccaggctac 397620 atgagggggg ccagaggggc tacggggcac cacagggtta atggtgacct cttggtcccc 397680 agagtgtggt gcgtgaatgg acccatggtg ttgggttgtg gagattcaag gatagtgccc 397740 cacctatggc cctgaatgca actgtccctg tttagcaatg ggccatctca gtgggtctcc 397800 tggagcctgg tggggggcag agttgtttcc ttgtgactgg gttaaggtag agctctggcc 397860 agcacctggt ggtgtggcag gtcagccctg ggactcttgg gcttttgacc aaggggcagc 397920 ctgtatcccg ctgggggtca tcctatctct gaggtcaagt gtcgtgaagg gtggcctcct 397980 gaagtgggaa ggctcgctgt cgagggacct gtcctaggat tttattgctc aggctgcttc 398040 tgagccatgg tgtcacctct agggtgatgg ggtcttggga acaagcaaag gggagggcac 398100 catgttgctc cggattgggc aagtgtggcc cagctctgtg tgtgtgaggt gtgcagaaca 398160 tggatggtga cccaccagag aaagcacatg gccctgtagc tctaggttgt gatttccgtg 398220 cacacttgga gacagcatct tgatgtgtgc ccaacacgcc caggggcaga ctatgcgata 398280 gccaggtctg cagcggtgtg tggcatctgg gccagccacc tttgttggcc atgagctggc 398340 tcatggccct gacccatgcc cactggtgtc agggggccct ggcgtcgtgt gaggagccat 398400 ctgtggcagt ggaggtagac tcagggcctg cagtatggcg caacccatgc attttgcctg 398460 agctcagtga cctacctgcc ctgttcctcc agggtttggt ggcaggggga gccaagggtg 398520 ccccacattg gtgacgagtt agtacttcac atggatctca taacatgtgt ccgtggaggg 398580 caagcaaatg tgagcccgca cccactactg ccttccccac atggaggtca gtttggacac 398640 atatcatcct gctgtccccc aaatggtgag accgaagaag acttgccctg ggccctctgt 398700 tcttgggcca gtgtcagtca gccaggtgcc cagctctaag tgcgctgaag cttgggcctt 398760 tcctggaatg ctcggctccc gcactgagcc agggtgagca catccgggta ctgctggatg 398820 catgtgtggg gcaggggtgc gccctgggtt gggctgatga tgagaacctt atattgtcct 398880 gaaaagaggt gatgacttaa caatcatgct caataggatt acattgaagc ccaggatagg 398940 taagaattag ggaagatgat gcagggatcc caagatctcc agctagacca cacttatttt 399000 gcactggaga acttgagaac ttgaagggca tctcagggga gcccaaccct gtctctgagc 399060 tccttcgtga ggcagcccag gctccccttg cgggcttggt gtctgtgctc cgcttctcca 399120 gggacagggc aatttggtgt tccttcctga atgctccttc ttccctgtgt ccttcagtga 399180 gctcttctgc ccaggtgggg tccctagctt tgagcggcat aggtcagtgc atcctgttgg 399240 ggtcatgggc catgagtgag gcagcatggg gttggtgaga gtcagccttc aggccactag 399300 ggttttctca gggagccaac cgattactca ccgggaggga tggttcctcc aggagggtca 399360 cttcttggga atctgaccct aggagcacac atttcctgaa gctcggcagg gagatggtgg 399420 tccaggcagg aaagggttcc ttcaacctaa cgtagggcag ttcccagctg aaactaggtg 399480 ggcaggtgag gcttgaggac tgcccagtcc acatgaaagg ggccacaggg gctttggggt 399540 gccctgggag tcatgctgga gttcttcccc caagagggat gggtgatagg gtccacgtgg 399600 tcaggctgcg gagattcaag gaatgccacc cacccatggc cctgaatggg accaaccctg 399660 ttgagcaatg ggccattttc ggcatgtttc aatgcagttg ggtcaaggct gagcgctggc 399720 tggtgcctgg tggtgctgca ggccggccct ggggctcatg ggctttatgc caagggggca 399780 actcccatcc cactggggta atcccttcct tgaggtccag tggtgggaag ggtggcctcc 399840 tgaggtgggc agacctgctg tcaagggacc tgtcctggga atttgccacc taggctgctt 399900 ctgagccatg gggtcacctc caggatggcg gggtcttcag cccaaggaaa ggagaggaca 399960 ccatgtggtt tctgattggc tgagtgtggc ctggctgtat gtgtgggagg tgtgcagggc 400020 atggatgggg actcatcaga gaaagaatgt ggccctggag gcccccaggc tttgatttct 400080 ggtgtgtgct tggagtgggc accagggtgg ccctaccatg cccaggggca aggtctttgc 400140 ctgccaggtc tggagtggct cctggcatca ggaccaccct ccttggctca accaaccttc 400200 agcaggttgg ctgccttggc ccgtgcccca tggtcccggt acgaccctgg ggttgttcgg 400260 gggatctggc ccaggcagtg gaggtgctct tggggcccac agtagggcac agcccaggcc 400320 tcttgcccca gcccagtaac ccacttgccc tgtctttcca gggttttgtg gcagggaagg 400380 ccaagggtgc tctgcgtcca tgttgggtca gtgttctgta aggattccat tacaagggta 400440 tcccctaccc accttcccta cattgataca tgaggccctg gttggacaca tgtcctcctc 400500 ctgtccctac agatggtgac cctgaagaaa gacttcagtt gggcctgaag gccccgggcc 400560 agtgtccatc atccaggtgc tcagctccca gtgcactgaa gctcagaccc ttcctggttc 400620 cctggtctct tgcactgagc tctggtgagc acaactgggt gctgctggat gcatgcatgg 400680 ggaggggggt gccctgggtt ggggtggtga tgagaacctt gtattcttct gaagagaggt 400740 gatgacttaa aaaccatgct caataggatt acacttaggc cgaacctagg tgagaatgtt 400800 ggaagaggac gttgggatcc tattatccct ggcagagcca ctgtattttg ggctggagac 400860 ctggaggccc tgaaagggca tctggagggg gcccaaccct gtctctgtgc tcctgcatga 400920 gggtccccag gctccctgtc cagccttggt gttggtgctc tggtaccctg gggatggaac 400980 aagttggtgg ctctttcctg agcccccatt ctccctttgt gtctttcagt gagcttttct 401040 gcccaggtgg gcaccctggc attgattagc ctccttggtt gtccatgacc tggctggtgg 401100 cccgatcctg tgcccagtgg tcccagggca gccctggcat catacggggc agctgttttg 401160 ggcagtggag gtgctctcca ggcctgaagt atggcacagc ctgggcattt tacctgagac 401220 cagtgacctg cctgccttgt ccttcctggg ttcggtggca gggagggcca agggtgccct 401280 gcgtcagtga tgagtcagta ttttgtgtgg atctcatcac ctgtccatgg agggaaagca 401340 agcatgagct ggcacccaac acccccttct ccgcatggag ggtggtcaca tgtcctccac 401400 ctgtgccccc agatggtgag acttgaggaa gacttccact gggcctgctt ttcctgagcc 401460 agtgcccatc acccaggtgc tcagtccctg gtgcactgaa gctccagccc ttcctggcgc 401520 cctggtctcc tgaactgagc tgtggtgagc acatccgggt ttcactggat gtttgtgcgg 401580 ggagggggtt ctctgggttg ggtcaatgat gagaacctta tattgtcctg aagagaggtg 401640 atgacttaaa aatcatgctc aataggatta cgctgaggcc cagcctaggg gagaattttg 401700 gcagaggatg ccgggatccc aagatttccg ggagggccac ttgtattttg ggttggagac 401760 ctggaggccc tgaagggcgt ctggaggtgg cccagtgctt tctttgcgct cctctgtgag 401820 gcagcccagg ctccctttgt gggcttggtg tttgcgctcc tcttctccag tgatggggca 401880 cgttgggggc tcctccctga gtcctggttc tccccttgtg tctttcagtg agctcttctg 401940 ccaagcggtt cccctggcat tgaccaacat aggtgagtgg atcctgctgg catcatgggc 402000 tatgagctag gccgcatggg tttgctgagg gtcagacttc aggccccaag ggtttcctca 402060 gggaaccgac ctcaattccc accatgtgac tgccaggttt gcaacagtgc atagcttccg 402120 agctaccctc cttggttggc cgggagctgg ttggaggctg tggcccatgc ctagtagtca 402180 cagggcaggc agactgccct gttttttcag ggtgtggtga cggggagggc caagggtgcc 402240 ctgcatccat gatgggtcag ggatttcagg agggatggtt tctccaggag ggcagcttcc 402300 ttgggaatct tacccaagga ggatgtcttc cctgaagccc tgcaggggtg acgatggtcc 402360 agatagcaaa ggtttccttc agccccatgc aggacatcac ctagttgaga tatggtatgt 402420 gggtcaggcc ttgaagactg cccaggccac ctgaggggcc cagaagggct ctggggtgcc 402480 acaggtgtta tgtaggagct ctcagtcccc agacttgttt cgtggggttg gtgacggggt 402540 tgggttgtgg aggttcaagg atttcatccc acctgtgacc ctgaatgggg ccaaccctgt 402600 tgagcaacag gccatcccaa tggcacgtat tgagcctggt ggggtgtggt gcagtttcaa 402660 tagggttgag tcaaggctga gatccatctg gtgcttggtg ctgctgctgg ccagccctgg 402720 gacccgtggg ctttgggcta agggggtagc ccacatccta ttgagggtaa cccattctcc 402780 gagtttgagt aacggttaac agtggcattc tgaggtggga aggcccactg tctagggtcc 402840 tatactggga atttgccacc ccgggttctt ctgagacaag tggtcacctc cagggtcatg 402900 gggtcttggg cccaaggaaa ggagaagata ccatgtggcc cttgattggc tacatgtggc 402960 ccaggtctgt ttgggaggtg tgtgggatgt ggatggggtc ccaccaatga aagcacatgg 403020 cctgggtccc caggctgtga ttttcagtgc acacttggag agggtgcctc ggcgggtacc 403080 taccacatcc atgggcaggc tatgtgacta ccaggtttgc aacagtgcat agcttccaag 403140 ctaccctcct tggttggtcg ggagctggtt ggaggctgtg gcccatgcct agtggtcaca 403200 gggcaggcag acggccctgt tttttcaggg tatggtgatg gggagggcca agcatccatg 403260 atgagtcggt gttccacatg gaacccatta cgtgggtatc tcttacccct tcctcatatg 403320 gagatgtgag gccctatttg gacacatatc ctcctcctgt acccccagat ggtgagcctg 403380 gaggaagact tgcgttgggc ccaaaggccc tagaccagtg tctgtcagcc aggttcccaa 403440 cccccgatgc gctgaagctc aagcctttcc tggcaccctg gtctcctgca ctgagctgtg 403500 gtgagtatat cctggtcctg ctggatgcat gtgcagggag gtgggtgcct tgggttgggt 403560 caatgatgag aaccttatat tgttctgaag agaggtgatt atttaaaaat catgctcaat 403620 aggattacgc tgaggcccag cctagttgag aattttggag gaggacactg ggataccgaa 403680 gtcccccgca gggactctgt attttgggct ggagaccttg aagccctgaa gggcatctgg 403740 aggtggccca acctgtctct gtgctcctcc ctgaggcagc ccaggctcct tttgtgggct 403800 tggtgttggg gctccagttc cccaggtcag ggaatattgg tagctcttta ctgagcccct 403860 gttctccctt tgtgtctttc agtgagctct tctgcccagg cgggccccct ggaattgatg 403920 ggtataggtg agtgcatcct gctggggtca tgggccatga gccaggccac gtggggtcac 403980 caggggtccc ccttctggcc atgagggttt tctcagggaa ccgacctgaa ttaccactgg 404040 ggaggcatag gttctccagg agggcggcta ttttgggaat cggatccaag ggggacacct 404100 tccctgaagc cctgtgggtg tgatggtggt ccaggcagga aagggtccct tccaccccac 404160 acagggcagc tcatagctga gagttgatgc tcaggtcagg cctcaaggat ttcccaggcc 404220 acatgagggg gacagaggag ctctgggtgc cacgggggtc acataggagc tctcagtatt 404280 cggtatgtca tgcacaaatg ggcctcttgg gttggattgt ggagattaaa ggatcgcgca 404340 ccaccgtggc cctgaatagg accatcctta ttgagcaatg ggccatccca gtgagtctcc 404400 tggagcctgg tggaggggag ggggtggcat tgtttccctg gggatgggtc aaggcagagc 404460 tctggccagc accttgtggc ttctgcaggt cagccttggg actcatgggc attgggccaa 404520 gggggagccc gcgtcccact gggggtcacc ctttttccga cgtcaagtat ctggaagagt 404580 ggcctcctga tgtgggaagg cctgctgtcg agggacgtgt cccaggagtt tgtcgctcaa 404640 gtttcttctg agctttgggg tcacatccag ggtggcgggg tcttgggccc aagcaaagca 404700 gagggcacca agtgtctcct gattggccat gtggctgtct ctgtgtgtgg gaggtttaca 404760 gagtatggat ggggacccac cagaggaagc acgtggccct gcagcaccag gctgtgattt 404820 ctgttgcaca cttggagagg ttgcctggac acgtgccctt catgcccagt gacagactat 404880 gcaactacca ggtctgcagc agggtgtgac atctgggcta gcctccttgg ttggccgcca 404940 cctggctggt ggcccggatc tgtgcccaac agtcccagtg cagcactggg gtcatgcagg 405000 ggagctgttt tggacagtgg aggtgctctc ggggcctgca atatgatgca gcctgggcgt 405060 tttgctcaag cccagtgacc cacctgccct ttcctttctg ggttcagtgg aagggagggc 405120 caacagtgta gtgcgtactt aacaagtcag tatttcacat tgaactcatc acatgtgtcc 405180 atggagggca agcaaaggtg agctggcacc cccgaccccc ttccccaaac ggaggtcagt 405240 ttgggcacac gtctccctcc tgtctcccca gatggtgacc ccggaggaaa atttgtgttg 405300 ggcccactat ccctgggcca atgtcagtca gctaggcacc cagcccccag tgcgctgaag 405360 ctcaggacct tcctagtgcc ctcggctcct gcactgagct ctggtgagtc catctgggtc 405420 ctgctggatg catgagctgg gggcgggagg gtgccctggg ttgggtcagt gatgagaacc 405480 ttatattgtc ctgaagaaag gtgatgactt aaaaatcatg ctcaatagga ttacactgag 405540 gcccagccta ggtgataatt ttggaagagg atgctggaat tctgaggtcc ctgacagagc 405600 agctgtattt tgggctggag accttgaggc cctgaagggc atcttgtggg cccaccccta 405660 tctctgtgct cctctgtgag gcagcccagg ctccctgtgc tggcttggta tccgggctct 405720 gggtccctgg tgacggggca tgttggaggc tccttcctga gcccctgttc tcccttgtca 405780 ttcagtgaac tcttctgcac aagtgacccc cccagccttg agcggcatag gtgagtgcat 405840 cctgttttgg tcatgggcca tgagtgatgc agcatggggt ccctgacatt ctgcctttgg 405900 gccaccaggg ttttctcagg ctgccaacct actccccacc agggagcgat ggtttctcag 405960 gagggctgct tccttgggaa tctgacccaa ggagcaagtc tctcctgagg ccctgcaggg 406020 gtgacagtgg tccaggctgg aaagggttcc ttcagcccaa tgtagggcag ctcccagctg 406080 aaactcagtg ggcaggtcag gcctcgagta ttgcccaagg cacatggggg agtgaggcac 406140 gggggataca gtgcgccgtg gaggtcacac tggagttctc ccctccctgg agagggatga 406200 gtgactgggt ccacacggtc aggctgtgga gattcaaggc atgctccaca cccatggcct 406260 tgaatgggac caaccctgtt gagcaatagg ccatcttagt ggcacctcct tgagcctggt 406320 gggggacggc actgtttcaa tgaggttggg tcaagagtga gctctggctg gcacctggtg 406380 gtgctgcagg ccctgggact tgtggacttt gggccaaggg agcagctctg atcctgctgg 406440 ggacaagcct tccttgaggt ccagtggtga aaagagtgtc ctcctgagat ggcaaggcct 406500 gctgtcgagg gacctgttct aggaatttgc tgcccaggct gcttctgagc cttggggtca 406560 cctcaggggg tggcagggtc ttgagcccaa gaaaggaaaa gacacgatgt ggttcctgat 406620 tggctgagtg tgacccggct ctgtgtgtca gagttgggca ggacatggat tgagacccac 406680 catagaaagc atgtgatcct ggaagcccct aggcttggag agggcaccag ggccagcgcc 406740 caccacgcct aggtacgatc tctcggactt ccaggtctgc agcggctctt ggcgtctggg 406800 ccagcatgct tggttggcca ggggctggtt ggtggccctg tcttgtgccc tgtgtccccg 406860 gtatggccct ggggttgtgt gtggtagcag gcctgggcag tggaggtgct cttggggcct 406920 gcagtagggt gctgcccagg catcttgccc gagccaggtg acacgcttgc cctgtctttc 406980 cagggtttgg cggcagggag ggccaagggt gcccagtgtc cgtgagggat cagtattcag 407040 catggatccc atcacatgag tatcccttag ccccttctct acattgatgt gtgaggccct 407100 ggttagacac atttcctcct cctgtccctc cagatggtaa gcctggagga agacttgtgt 407160 tgggcccaca ggccccaggc caatgtctgt cagccaggtg ctcagcctct ggtgcgctga 407220 aactctgacc cttcctggca cactggtctc ctgcactgag ctggggtaag cacatctggg 407280 ttgcactgga tgtttgtgtg gggagggggt tccctaggtt gggtcaatga tgagaacctg 407340 atattgccct gaagagagat gatgacttaa aaatcatgtt caataggatt acgctgaggc 407400 ctagcctagg tgagaatttt ggaagcagat gctgggatcc caaggtccct tgcagggcca 407460 tcgtatgttg aactggagac ctggaggctc tgaagggcat ctggaggtcg tgcaacctgt 407520 ctctgcactc ctctgtgagg cagcccaggc tccctgtgtg gggttggtgt tggtgctatg 407580 gttccctggg ggtggggaac attggtggct ccctccagag cccctgttct caccttgtgc 407640 ctttcagatt ttccacctag gaggtccacc tggcattgac tgacataggt gagtggatcc 407700 tgctggggtc atgggtcatg agccagacca tggggggatc ccagagattc agtctttggg 407760 caacagtttt ctcagggagc agacctgaat ttccacctgg gagggaaggg ttctcctgga 407820 gggcgacttt tttgggaatc ggacccaagg aggatgcctt ccctgaagcc ctgccggggt 407880 gatggtggtc caggcaggaa agttccttct gctcaatgca gggcagcacc cagctgagac 407940 tcggtgctcc ggtaaggcct ccagaactgc ccaggtcaca taaggggggc cagaggggct 408000 acgaggtgcc acggggtaac aggggagctc ttggtcccca gagtgtggtg catgaatggg 408060 cccattccgt tgggtctcag agatttaagg attgcaccac accatggccc tgaatgcaac 408120 cgtccctgtt gatcaatggg ccatcccatg ggtctcctgg agcctggtgg gaggcagtgt 408180 tgttttcctg gggttgggtc aaggcggagc tctggctggt acctggtggt gctgcaggtc 408240 agccctggga cttgtgggct ttgggccaag gggcatcccg catcccgctg ggggccaccc 408300 tttctccatg gtcgagtgtc gtgaagggtg gcctcctgag ttgggaaggc ttgctattga 408360 ggcacttgta ctgtgaattt gttgctcagg ctgcttggga gccatggtgt cacctccagg 408420 gtggcagggt cttgggacca agcaaaggag tgggcaccat gtcactgcag ataggccatg 408480 tgtgactggc tctgtgtctg ggagatatgt ggagtatgaa tggggaccca ccattcatag 408540 agaaagcaag tggccctgca gcccgaggct atgatttccg gtgcacactt ggagagggtg 408600 cctttacacc caagtaccag gctcagaggt aggctatgcc actatcaggt ctgcagtggc 408660 acgtggcatc tgggccagcc tccttggttg gccatgacct ggctggtggc ctgggcctgt 408720 gcccagtgtt cccagggtag ttctagggtg ctgcggggga gctgttttgg ctagtggagg 408780 tgctcttggg tcctgcagta cagcacagcc tgggcgtttt gcctgagccc agtgacctgc 408840 ctgccttgcc cttcccagga tcggtggtag ggaagaccag gggtgcccgg cataggtgat 408900 gagtcagtat ttcacatgga tatcatcaca tgtgtccatg gagggggagc aaacatgagc 408960 tggcacccgc cacccccttc tccacatgaa gggtggtcac acgttctcca tctgttcctc 409020 cagatggtga gacttctgtc ggcctcgctt ttcctgggcc agtgtccatc agccaggtgc 409080 tcagccccag tgcactgaag ctccagccct tcctggcgcc ctggactgag ctgtggtgag 409140 cacatccggg ttccactgga tgcgtatgtg ggaagggggg tgccctgggt tgggtcaatg 409200 atgagaaccg tatattgtcc tgaagagcgg tgatgactta aaaataatgc tcaataggat 409260 tacgctgagg cccaccctaa gtgagaaatt tggtagggga tgttgggatc ccgagatttc 409320 tggcagggcc actgtagttt gggttggagg cctggaggcc ctgaagggca tctggaggtg 409380 gctcaactct ttctctgtgc tcctccgtgt agcagcccag gctccctgtg cgggcttggt 409440 gttgttgctt ctgttccttg ggggcagggc atgtgggtgg ctcctccctg agccccagtt 409500 ctccccttgt gtctttcagt gagctcttct gccaaggggg tcctcctggc attgaccaac 409560 ataggtgagt ggatcctgct gctgtcatgg tccgtgagcc aggctgcttg gggttgccaa 409620 gggtcagact tcgggccatg aaggtttcct cagggagctg accctaattc ccatgaggga 409680 ggcatggttt ctccaggagg tcagcttcct tgggaatctg tgacttgaca gggttgagtc 409740 gcagaggttc aaggatctca tcccacctgt aaccctgaat ggggcccacc ctgttgagca 409800 actggccatc ccagtggcac atattgagcc tggtgggggg tggtgcagtt tcaatggggt 409860 tgggtcaagg ctgagatatg gctggtgcct ggtggtgctg cagtccagcc ctgggatccg 409920 tgggctttgg gctgaggggg aagcctgcat cctattgggg gtaacctgtt ctccaaattt 409980 gagtgattgg tgggaaggcc tactgtctga ggtcctgtac tgggaatttg ccacctcagc 410040 ttcttctgag ccatagggtc acctccaggg tcatggggtc ttgggaccaa ggaaaagaga 410100 agataccatg tggcccttga ttggccgagt gtagcccagc tctgtgtttg ggaggtgtgt 410160 gggatgtgga tagggtccca cctgtgaaag catgtggccc gggtccccag gctgtgattt 410220 tcagtgcaca cttggagagg gcaccttggt gggtgcccac catgtccagg ggcaggctat 410280 gtgactgcca ggtttgcaat ggtgtgtagc ttccttctac cctccttggt tggctgggag 410340 tgggttggtt gctgtggccc atgcccagtg gtcacagggc aggcagactg ccttgttttt 410400 tcagggtatg ctgacaggga gggccatggg tgccctgcat tcatgatgag tcagtgttcc 410460 acatggaacc cattatgtgg gtatctctta ttccttctac atatggagat gtgaggccct 410520 atttggacac atgtcctcct cctgtacccc caggtggtga gcctggagga agacttgcat 410580 tgggcccaat ggccctggac cagtgtctgt cagccaggtt cccagccccc gatgcgctga 410640 agctcaagcc tttcctggca ccctggtctc ctgcactgag ctgtggtgag catatcctgg 410700 tcctgctgga tgcatgcgtg gggaggggtt gtcctaggtt gggtcaatga tgagaacctt 410760 ataatgttct gaagagaggt gatgacttaa aaatcatgct caataggatt acgctgaggc 410820 ccagcctagg tgataatttt ggaagaggac actgggtccc gaagccccct gcagggcccc 410880 tgtgttttgg gctggagacc ttgaggccct gaaaggcatc tggtggaccc aactctatct 410940 ctgccctcct caatgaggca gcccagcctc cctgtactgg cttggtatcc gggctccggg 411000 tctctgggga cggggcacat tggaggctcc ttcctgagcc cccattctct cctgtgtctt 411060 tcagtgagct cttcggccca agtggtcccc ccggccttaa gcggcatagg tgagtgcatc 411120 ctgttttgat catgggccat gagtgttgca gcatggggtc cccgacattc agccttcagg 411180 ccactaggct tttctcaggc tgcaaaccta ctctccacca gggagcgatg gtttctcagg 411240 agggccactt ccttcggaat ctgacccatg gagcacgcct ttcctgaagc cctgcagagg 411300 tgacagtggt ccaggcagga aggggttcct tcagccccaa tgtagggcag ctcccagctg 411360 aaacttggtg gacagatcag gcctggagta ctgcccaggg catatgggga ggagggacac 411420 agggaatgtg gcgcacccta gaggtcacac tggagttctg tctccctgga gaggggtgag 411480 tgattgggcc cacatggtca ggctgtggag attcaaggaa tgctccacac cgatggcctt 411540 gaatgggacc aaccctattg agcaatgggc catcttagtg gcacctcctt gaacctggtg 411600 ggggatggca ctctttcaat gaggttgggt caaggctgag ctctggctgg cacccagtgg 411660 tgctgcaggc tggccctggg acttgtgggc tttgggccaa gggggaagct tccatcctgc 411720 tgggaacaac ccttccttga ggtccagtgg caggaagggg ggcttcctga ggtggaaagc 411780 cctactgttg agggacctgt cctgggaatt tgctgtccaa gctgcttctg agccatgggg 411840 tcacctctag ggtggtgggg tcttgagccc aaggaaagga gaggacacca tgtggttcct 411900 gattggctga gtgtggcccg gctctgtgtg tcggagttgt gcagggtatg gattgggacc 411960 caccagtgaa agcacatggc cctggaggtc cgcaggcttg gagagggcac cagatctggc 412020 acccaccatg cccaggtaca ggctctggga ctgccaggtt gcagcagctc ttggcatctg 412080 ggccaccctc cttggttggc caggagctag ttggtggccc tgtcccatgc cccatgtccc 412140 tggtatggcc atggggtcat gcagaggaac cggccctggc atggaggtgc tcttgcaaca 412200 tgcagtaggg tgcatcccag gcatcttgcc tgagccaggt gacccgcttg ccctgtctct 412260 ccagggtttg gtggcaggga gggccaaggg tgccccgtgt ccatgttggg tcagtgttca 412320 gcatggatcc cattgcatga gtatcactta gctccttccc agcattgata tgtgaggccc 412380 tggttggaca cttgtcctcc tgtccctcca gatggtgagc ctggaggaag actcgtgttg 412440 ggcccacagg ccccaggcca gtgtacgtca gccaggtgct cagcccatgg tgtgctgaag 412500 ctctgaccct tcctgactcc gtggtctcct gcactgagct gtgatgacca tatccaggtc 412560 ctgctagatg catgcgtggg gaggcagggt gccctgggtt gggtcaatga tgagaacctt 412620 gtattatctt gaagagaggt gatgacttaa aaatcatgct caataggatt acactgaggc 412680 ccagactagg tgagaatttt ggaagaggat gctgggatcc tgaggtcccc aacagggcca 412740 ccatattttg ggctggagac ctggaggtcc tgaagggcat ctgtaggggg cccaaccctg 412800 tctctgcact cctccctgag gcagcccatg ctccctattc gggatcggta ttggtgctcc 412860 acttccctgg gggcaggaca cgtgggtggc tactccctga gcccccgttc tccccttgtg 412920 tctttcagtg agctcttcca aacaggtggg ctccctagca ttgaccgaca gaggtgagtg 412980 gatccttctg ggattatggg ccatgagcca ggccatgtgg ggtccccaag gttcagcctt 413040 tggatcccga gagttgtctc agacagccaa cctgatttgc cacctgggag agatggcttc 413100 tccaggaggg tgggtttttg ggaattggac ccaaggagga cgccttccct gaagccctac 413160 tgggatgatg gtggtccagg caggaaaggg ttccttcacc cagctgagac tcggtgttcc 413220 agtaaggcct caaggacctc cctgccacat gaaggggccc agaggggcta cgaggcacca 413280 caggagtgac aggggagctc ttggtcccca gagtgtggta catgaatggg cccatggggt 413340 tgagtcgcag agattcaagg atgctgcacc acccatggcc ctgaatgtga ctctcctcct 413400 ggagcctggt ggggggtggc gttttttccc tggggttcgg tcaaggtgga actctggtca 413460 gtacctggtg gtaatgtagg tcagccctgg gactcgtggg ctttgggcca acggacagcc 413520 cacatccctc tgggggtcac cctttctctg aggtcgagtg tcgtgaaggg tggcctcctg 413580 aggtgggaaa gcccaatgtc gaaggacctg tactgagaat ttgttgctta ggctgcttag 413640 gatccatgtt gtcacctcca gggtggtggg atcttgggac caagcaaagg agagggcacc 413700 atgtggctgc cagtggctat gtgtgactgg ctctgtgtct gagaggtgtg tggatgggga 413760 cccaccagag aaagcaagtg gccctgcagc cccaagatgt gatttctggt gcaggcttgg 413820 agagggtgcc tatacctgct cccaccacgc ccaggggcag gctttgccac tgcaggtctg 413880 cagtgccacg tggcatctgg gccagccacc ttggttggcc gtgacctggc tggtagcccg 413940 tgcctgtgcc cagtgttccc agggctgccc tggggtcttg ctggggagct gttttgggca 414000 gtggaaatgc tcttggggcc tgcagtatgg cacagcctgg gggcattttg cctgagccca 414060 gtgacctgcc tgccttgtcc ttcctgggtt cggtggcagg gagggccaag ggtgccctac 414120 attggtgaca agtcaatatt ttgcatggat ctcatcacgt gtccatggag gtgggggcaa 414180 gcgtgagctg gcacgcaccc cattctcccc atggagggtg gtcacatgta ctccacctgt 414240 gtccctagat ggtgagactg gaggaagact tccattgggc ccacttttca tgggacagtg 414300 tccatcagcc aggtgctcag cccccagtgc attgaagacc cagcccatcc tggcacccta 414360 gtctcctgca ctgagctgtg ctgagcacat ctggcttcca ctggaagttt tttttgcgag 414420 gaggggcttc cctgggttgg gtcaatgatg agaaccttat attgtcctga agagaggtga 414480 tgacttaaaa atcatgctca ataggattac gctgaggccc aacctagggg agaattttgg 414540 aagaggatta tgggatccca aggtccccaa caaggccact gcattttggg ctagagacct 414600 ggaggctctt aagagcatct ggaggtggcc caacctgtct ctgctccttc gtgatgcagc 414660 ccaggctccc tgtgtgggat tggtgttggt gctccatttc cctggcatgg ggaatgttgg 414720 tggctccttc ctgagctcct gttctcgcct tgtgtctttc agtgagctct gccacccagg 414780 acatccccct ggcattgact ggcataggtg agtggatcct gctggggtca ttggtcatga 414840 gccagaccat gtggagtccc caaggttcag cctttgggcc acaaaggttt tctcagggag 414900 cagacctgaa tttcacccgg gagggaaggg ttgtcctgga gggtggcttt tttgggaacc 414960 taacccaagg aggacccatt ccctgaagcc ctgcaggggt gatggtggtc caggcaggaa 415020 agggttcctt ctgctcaatg cagggcaaca cccagctaag atgcggtgat ctggtaaggc 415080 ctccagaact gcccaggcca tatgaggggg gccagagggg ctacagggtg ccacaggggt 415140 aacaggggag ctcttggtcc ttggagtgtg gtgcctgaat ggacccatgg gattgggttg 415200 tgtagattca aggatcacac cctacccaca gccctgaatg tgactcttcc tcttgagcaa 415260 tgggccatct cagtgggtct cctggagcct ggtcgggggg tggtgttgtt tccctggggt 415320 tgggtctagg tggagctctg gctggtacct ggtggtgctg cagatcatcc ctgggacttt 415380 tgggctttgg gccaagggac agcccgcatc ccgcttgggg tcagcctatc tccatggtca 415440 agtgtcatga agggtggccc cctgaggtga gaaggcctac tgtcaaggga tctgtcccag 415500 gattttgttg ctcaggctgc ttctgagcca tggcgtcaca tccacagtgg cagggtcttg 415560 ggcctgagca tagcagaggg caccatgtcg ttctggattg gccaagtatg gcctagctct 415620 gtgtgcggga ggtgtgcaga gcatggacgg tgacccacca gagaaagcac gtggccctgc 415680 atcccaggct gtgatttcca atgcacactt ggagagggtg tcttgatttg tgcccaccat 415740 gcccaggggc agactacgtg atagccaggt ctgcagcctg agccacgtgt ggcatctggg 415800 ccagccacct tggttggccg tgagctggct ggtggccttg gcctgtggcc agtggtgcca 415860 gggcggccct ggggtcgtgt gggggagcca tgttgggcag tggaggtgct gtcagggcct 415920 gcagtacagt gcagcctggg catttggcct gagcccagtc acccgcctgc tctgttcctc 415980 cagggtttgg tggcggggag ggccaagggt gccccgcatc cgtgacgact cagtaattca 416040 catggatcac atcacatttt tccttggagg gcaagcaaat gtgagccccc accccccact 416100 gccttcccca catggaggtc attttggaca catatcctcc tctagtcccc ctagatggtg 416160 agactggagg aagacttgca ttatgcccgc tgttcctggg ccagtgtcag tcagccaggt 416220 tcccagctcc aagtgtgctg aagctcaggc ccttcctggc accctcagct cctgcactga 416280 gctggggtta catccgggtt ccactgtttg catgcaaagg gaggggtgta ccctgggttg 416340 ggctgatgat gagaacctta tattgtcctg aaaaaaggtg atgacttaaa catcatgctt 416400 aatagtatta tgctgaagcc caagctaggt gagaattttg gaagatgagg ctgggatcct 416460 gagatccccg gcagggccac acttattttg ggctggaaaa tttcaagacc tgaagcgcat 416520 cttgtggggg ggcaatcctg tctctgtgct tctccgtgag gcagcccagg ctcccgttgc 416580 gggcttggtg cccatgcttc gcttccccag gggtggggca atttggcatc ctcttcctga 416640 gccctccttc ttccctgtgt ctttcagtaa gttcttcttc ccaggtgggg cccctggctt 416700 tgagcggcat gggtcagagc atcctgtcag ggtcatgggc catgagtgag gcagcgtcgg 416760 ttcgtcgaga gtcagccttt gggccactgg ggttttctca gggagccaac aggttaccca 416820 tcaggaggga tggttcctcc aggagggtcg cttccttggg aatctgactc taggagcatg 416880 catttcctga agctctgcag ggtgatggtg gtccaggcgg gaaagggttc cttcagccca 416940 acataatgca gttcccagct gaaactcggt ggcagatcag gctcaaggac tgctcgggcc 417000 acatgatggg ggccacaggg gatttggggt gccctggggg tcatgctgga gttcttgccc 417060 caagaggggt gggtgatagg gcccatgcga tcaggctgcg gagattcaag gaatgctacc 417120 cacccatggc cctgaatggg actgaccctg ttgaacaatg ggccatttta atggtgcctc 417180 cttgagcctg gtaggtagtg gcattgtttc aatgcggttg ggtcaaggct gaactctggc 417240 tggtgcccgg tggtgcccac atgggctttg ggccaagggg gcagctcata tccctctggg 417300 gtcacccctt ccttgagatt cagtggcagg aagggtgttc tcctgaggtg gaagacctgc 417360 tgtcaaggga cttgtcctgg gaatttgcca cctaggctgc ttctgagcca tggagtcacc 417420 tccagggtgg cagggtcttg agcccaggga aaggagacac catatggttt ctgactggga 417480 gtgtggcctg gatctgtgtg tgggaggtgt gcagggcatg gatggggacc catcagagaa 417540 agcatgtggc cctgtaggcc cccaggcttt gatttctggt gtgtgcttgc agtgggcacc 417600 agggcagccc taccatgccc aggggcaggc tctgtgactg ccaggtctgg agtggctcct 417660 ggcatgaaga ccacgctcct tggttggcca tgagcaggtt ggttgcccta gcctgtgccc 417720 tgtggtcctg gtgcagccct ggggttgttt ggggagacag caccggcagt ggaggtgctc 417780 tcaaggcctg cagtagggcg cagcccaggt gtcttgcccg agcccagtaa cccacttgcc 417840 ctgtctttcc agggtttggt ggcagggagg gccaactgtg ccccgcatct gaaatggatc 417900 agtgttctgc atggatccca tcacaagggt atcccctacc caacttctgt gcattgttat 417960 gtgaggccct ggttggacac atgtcctcct cctgtccctg cagatgctga ccctggagga 418020 agacttgtgt cgggccccca ggccccaggc cagtgtccat cagccaggtg ctcagctccc 418080 agtgcgctga agctcagacc cttcctggca ccctggtgtc cagcactgag ctgtggtgag 418140 cccatccggg tcctgctgga tgcatgaatg gggaggggcc tgcccagagt tgggtcaatg 418200 atgagaacct tacattgtcc tgaagagaga tgatgactta aaaatcatgc tcaataggat 418260 tacgctgagg cccagcctag gtgagaattt tggaagagga cggctgggat cctgagatcc 418320 cagtcagggt cactgtattt tgggctggag acctggaggc cctaaagggc atctggaagg 418380 gggcccagcc ctgtctctgt gctcctccgt gaggcaaccc acactccctg tgtgggcttg 418440 gtgttggtgc tctggttccc cagggacagg gcgggttggt ggctccttcc tgagccccta 418500 ttctcccttt gtgtctttca gtgagctttt ccacccaggt gggccccctg gcattgaccg 418560 acataggtga gtgcatccta ctgggataat gggccactag atagtctgtg tggggttgct 418620 gaggtttagc ctttgggcca caagggtttt ctcaggcagc caacctgaat tcccacctgg 418680 gagagatggg ttctccagga ggcagctttt ttgggaatca gacccaagga ggacaccttc 418740 cctgaagccc tgcaggggtg atggtggtcc aggcaggaaa gggttccttc tgcccaactc 418800 gaggcccaat gcagggcagt gcccccctga gaattggtgc tctggtaagg gctcgaggac 418860 tgcccaggcc acatgaagga ggtcagaggg gctatgggga accatggggg caacagggga 418920 gctcttggcc cccggagtgt ggtacatgaa tgggcccatg gggttgggtc acggagattc 418980 aaggattgca tctcacccac ggccctgaat gcgaccatcc ctgttgagca atgggccatc 419040 ccagtgggtc tcctggggcc tggtgtgggg tggcattgtt ttcctggggt tgggtcaagg 419100 cggagctctg actggtacct gatggtgctg caggtcagcc ctgggactcg tgggctttgg 419160 gccaagaggc agcccgcatc ctgctggggg tcgccttttc tccgaggttg agtgtcgtga 419220 aggatggcct cctgaggtgg gaaggcccac tgtcaaggca cctagactag gaattgttcc 419280 tcaggctgct tgggagccat ggtgtcacct ccagggtggc gggatcttgg gactaagcaa 419340 aggaggggac actacgtggc tcccaattgg ccatgtgtgg ctggctctgt gcctgggaag 419400 tgtgtggagt atggatgggg acccaccaga gaaagcaagt ggccctgcag tcccagaatg 419460 taatttctgg tgtaggcttg gagagggtgc ctatatgcat gcccaccatg cccaggagca 419520 ggctatgcca cttcagggtc tgcaggggca cctggcatat gggccagcct ccttcgttgg 419580 ctgtgacctg ggtggtggcc tgtgcttgtg cccagtggtc ccagggtagc cctggggtcg 419640 tgcaggggag ccgttttggg cagtggatgt gctctcgggt cctacagtac agcacagcct 419700 gggtgttttg ctcaagccca gtgacctgcc tgccttgtcc ttcccgggtt cagtggcagg 419760 gagagccaag ggtgccccac attggtgacg agtcagtatt ttgcatggat ctcatcacac 419820 gtgaccatga aggacgagca agcatgagct ggcaccagcc acccccttct ccgcgtggag 419880 ggtggtcaca tgtcctccac ctgtgccccc agatgatgag actggaggaa gacttccatt 419940 gggcccactt ttcctgggcc agtgtccatc agccaggtgc tcagcccctg gtgtactgaa 420000 gctccagcct ttcctggtgc cccagtcttc tgcactaagc tgtggtgagc acatccgggt 420060 tccactggat ttttgtgcgg ggagggggtt ttctacgttg ggtcaatgat gagaatctta 420120 tattgtcctg aagagaggtg atgacttaaa aatcatgctc aataggatta cgctgaggcc 420180 cagcctaggt gagaattttg gaaggggatt atgggatgct gaggtcctca gcaaggccac 420240 tgtattttgg gctagagacc tggaggctct gaagggcatc tggaggtggc ccaacctgtc 420300 tctgcgctcc tccatgaggc agcccaggct ccctgtgcag ggttggtgtt ggtgctccgg 420360 ttctctggtg tggggaatgt tggtggctcc ttcctgagcc ctcattctca ccttgtgtct 420420 ttcagtgagc tcttccaccc aggagggccc cttggcattg actggcatag gtgagtggat 420480 cctgctgggg tcattggtca tgagctagac cgtgtggggt ccccgaggtt cagccttcag 420540 tccacaaggg ttttctcggg gagcagacct gaatttccac ctgggaggga agggttctcc 420600 tggagggtag tttttttggg aatctagccc aaggaggatg ccttccctga agccctgcaa 420660 gggtgatggt ggtccaggca ggagagggtt ccttctgccc aatgcaggac agctcccagt 420720 tgagactgag tgctccagta aggtctccag gactgcccag gccacatgaa ggaggccaga 420780 ggggctatgg agcaccactg gggtaatagg ggagctcttg gtccctggag tgtggtgtgt 420840 gaatggggtt tggtcacgga gattcaagga tcacacccca cccatggccc tgaaagtgac 420900 catccctatt gagcaatggg ccatcccacc gggtctcctg gagtctggtg cagggcgacg 420960 ttttttccct ggggttgggt caaggtggag ctctggtacc tggtcatgct gcaggtcagc 421020 cttgggactc gtaagctttg ggccaaggga cagctggcat cctgctgggg ggtcacccta 421080 tctctggggt cgaatgtcac gaagggtggc ctcctgaggt gggaaggccc attgtcgagg 421140 gacctgtccc aggattttgt tgctcaggct tcttctgagc catggtatca cctccagggt 421200 gacagggtct tgggcccaag caaaggagag ggcaccatgt cgctctgagt tggccaagtg 421260 tagcctagct ctgtggtggg aggtgtgcag agcatggctg gtgacccacc agagaaagca 421320 cgtggccctg cagccccaag ctgtgatttc cagtacatgc ttagagaggg catcttgatg 421380 tgagcccacc acacccaggg gcagactacg tgactgccag gactgcagtg gcacatggca 421440 tctgggccag ccttcttggt tggccatgac ctagctaatg gccctggccc gtgccttggg 421500 gtcatgcagg ggagccctct tggacagtgg aggtcctctc agggcctgca atatggcgca 421560 ggctgggcat ttggcccgag cccagtgacc tacctgccct gtccttccag ggttgggtgg 421620 cagggaggga caagggtgcc ccatgtcagt gacaagtcag tatttcacat ggatctcatc 421680 acatgtgccc atggaggacg agcaagcggg aactggcacc cgctacttcc ttccctacat 421740 agaggccatt ttggacacat gttctccacc tctctcccag atggtgagac gggaggaaga 421800 cttgtgttgg gcctgctgtt cctgggccag tggccatcag cctgttgccc agcccctgag 421860 gcgctgaagc tcaggccctt cctcacaccc tggtctcctg cactagctgt ggtgagcaca 421920 tccgggtccc gctggatgca tgcaagaggt ggttggtctc gtgggttggg tcgatgatga 421980 gaaccttata ttttcctgaa gagaggtgat gacttaaaaa tcatgctcaa taggattacg 422040 ctgaggccca gcctaggtga gaactttgga agaggatgct gggatcctga gatcccaggc 422100 agggccacta tattttgggg tggagaactc aaggccctga agggcctctc agggggtgcc 422160 accctgtctc tgtgcccctc tgtaaggcag cccaggctcc ctgtgtgggc ttggtgtctg 422220 gtctctggtt ccccgggggc ggggcatgtt ggtggctcct tcctgagccc gctttctccc 422280 ccatgtcttt cagtgagctc ttctgcccag gtggggccca tggccttaca cgacataggt 422340 gagtgtatcc tgttggggtc atgggccatg aatgaggcag catggggcca tttagggtca 422400 gccttcgggc cactagagtt ttctcagggt gcgaccgggg agggaacatt tctccagtag 422460 ggtcacttcc ttggaaatct gatcctagga gcacgcattt cttgaagtcc tgcaaaggtg 422520 atggtggtcc agacaggaga gggttccttc agcccaacat agcgcagctc ccagctgaaa 422580 ctcggaaggc tggtcaggcc tcgaggactg cccaggccac atgaggtggg caacaggggc 422640 tctggggcaa cctgggggtc acgctggagt tctccctctc tggacagtgg tgggtgattg 422700 ggcccacgca gacaggcccc ggagattcag gactgcaccc catccatggc cctgaatggg 422760 accgaccctg ttgagtaatg ggccatctca gtggtacctc cttgagcctg gtagggggag 422820 acactgtttc aatgcagttg aatcaaggct gagctctggc tggtgcctgg tggtgctgca 422880 ggcagccctg agggttgtgg tctttgggac aaggggtagc tcacatccca ctggggtcac 422940 cccttccttg agattcagtg gccaaaaggg tgtcctcctg agatgggaag tcctgctgtc 423000 gagggacctg ttctgggaat ttgccacaca ggctgcttct gagccacggg gtcacctcca 423060 gggtggtagg gtcttgatcc caaggaaagg agaggacacc atgtggtttc ttattgacca 423120 agtgtggcct ggctttgtgt gtgggaggtg taacgcaaga tgaggaccca ccagagaaag 423180 cacgtggctc tggaggcccc cagggtttga tttccggtgt gtgcttggag agggcaccag 423240 gttgggcacc caccacgccc agggcaggct ctgcgactgc caggtctgca ttggctcctg 423300 gtgtcagggc cagactcatt ggttggccat gagcaggttg gttgccctga cccatcccca 423360 tggtcccagt gtggccctgg ggtttttcag gggagccggc tcaagcagtg gaggtgcgct 423420 tagggcctgc agtagggaac agcccaggca tcttgcctga gcccagtaac ctgcttgcct 423480 tgtctttcca gggtttggtg gccgggaggg ccaatgatgc tctgcgtctg tgttggatca 423540 gtgttcttca tggattccat cacgtgggta tcccctaccc accttcccct tgctcatacg 423600 tgaggccctg gttggacaca tgtccttctc ctgtcacccc agatggtgag ccttgaggaa 423660 gacttgtatt gggcccccac aggccccagg ccagtgtccg tcagcctggt gctcaccccc 423720 agtgtgctga agctcagacc ctccgtggca ccctggtctc ctgcactgag ctgtggtgag 423780 cacattcagg ttccgctgga tgcatgcatg gagaggggct tgcccttggt tgggtcagtg 423840 atgagaacct tctattgtcc tgaagagagg tgatgactta aaaatcatgc tcaataggat 423900 tacgctgagg cccaacctag gtgagtatgt tggaagaaga cactgggatc ccgagatctc 423960 caacagggca ctgtattttg ggttggagac ctggaggccc tgaagggcat ctggaaggag 424020 gcccaaccct gtctctgtgc tcttccttgg ggcagcccag gctacctctg cgggcttggt 424080 gttggtgctc cagttccctg gggccaggga acattgctgg ctccttcctg agcccccatt 424140 cctcccttgt gtctttcagt gaacttttcc tcccagatgg gccccctggc attgactggc 424200 ataggtgagt gcatcctgct ggggtcatgg gccatcagcc aggccatgtg gggtcgctga 424260 ggttcagcct ttgggccaca agggttttct caggcagccg acctgaattc ccacctggga 424320 gagacgggtt ctccaggagg gcagcttttt tgggaattag acccaaggag gatacctgaa 424380 gccctgcagg ggtgacggtg gtccaggcag gaaagggttc catcagcccg ggcaaggcag 424440 ctcctagctg acactcggtg ttcgggtcag tccttgagga ctgcctgaac acgagggggt 424500 ccagaggggc tctgggtgcc acgggggtca catgggagct ctcagtccct agagtgtggt 424560 gtgtgaatgg acccttaggg ttaggtcttg gagataaaag gattgtgctc cacccatggc 424620 ctggaatgtg accgtccctg ttgagtaatg ggccattcca gtgggtctcc tggagcctga 424680 tgggaggtgg cgttgtcttc ctggggttga gtcaaggcag agctctggcc catacctggt 424740 tgtgctgcag gtcagccctg ggactcgtgg gctttgggcc gaggggcagc ccgcatcccg 424800 ctggagatta ccctatctct gagatcaagc gtcatagagg gtgacctcct gagaagggaa 424860 ggcccactgt cgagggacct ttcctaggat tttgttgctc aggctgcttg gaatccattg 424920 tgtcacctcc agggtgatgg aggtttgggc ccaagcaatg gagagggcac catgtgtctc 424980 ctgattgttc aagtgtgtcg gagatatgcg gggtatggat ggtggcccac caaagaaagc 425040 atgtgactca agctgtgatt tccagtgcat gcttagagag ggcgcctgta tgcgtgcccc 425100 acatgcccgg ggtaggctat gcaactgcca ggtctgcagt ggcgcatggc atcttggcca 425160 gccttcttgg ttggccatga cctggctaat gaccctggcc tgtgcccagt gatcccaggg 425220 aagccctggt gtcatgcagc ggaggcctct tgggcagtgg aggtgctctt aaagcctgca 425280 gcatggcacg gcctgggcat ttatcccaag cccaatgaac tacctgccct gtccttccag 425340 ggttcggtgg caggcagggc caagggtgcc ccgtgttggt gacaagtcag tatttcacat 425400 ggctctcatc acatgtgtcc gtggaagata agcaagtgtg aactggcacg tcctacctcc 425460 ttccctacat ggaggtaact ttggacacat gttctccacc tctctcccag atggtgagac 425520 cggaggaaga cttgcattgg gcctgttgtt cctgggccag tggccatcag cctgttgccc 425580 agcccctgat gcgctgaagc tcgggccctt cctcgcgccc tggtctcctg cactgagctg 425640 tggtgagcac atccgggtcc tgctggatgc atgcacgagg tgattgatcc cctcagttgg 425700 gtcgatgatg agaaccttat attgttctga agagaggtga tgacttaaaa atcatgctca 425760 ataggattac gctgaggccc agcctaggtg agaattttgg aagaggatgc tgggatcccg 425820 agatccctgg cagggccact atattttggg ctggagaact tgaggccctg aagggcatct 425880 caggggggtc caaccctatc tctgtgcccc tccatgaggc agcccaggct ccctgtgtgg 425940 gcatggtgtc cgggctctgg ttccctgggg gtggggcatg ttggtggctc cttcctgagc 426000 ctgctttctc ccccatgtct ttcagtgagc tcttctgccc aggtgaggcc catggcctta 426060 agcggcatag gtgagtgtat cctgttgggg tcatgggcca tgaatgaggc agcatggggc 426120 catttatggt cagccttcgg gccactaggg ttttctcagg gtgcgaccgg ggagggaatg 426180 tttctccagt agggtcactt ccttgggaat ctgaccctag gagcatgcat ttcgtgaagc 426240 cctgcaaagg tgatggtggt cccggcagga aagggttcct tcagcccaac atagagcagc 426300 tcccagctga aactcagcgg gctggtcagg cctcgaggac tgcccaggcc acatgaggtg 426360 ggcaacaggg gctctggggc aacctggggg tcacgctgga gttctccctc tctggacagt 426420 ggtgggtgat tgggcccacg cagacaggcc ccggagattc aggactgcac cccatccatg 426480 gccctgaatg ggaccgaccc tgttgagtaa tgggccatct cagtggtacc tccttgagcc 426540 tggtaggggg aggcactgtt tcaatgcagt tgaatcaagg ctgagctctg gctggtgcct 426600 ggtggtgctg caggcagccc tgggggttgt ggtctttggg acaaggggcc agctcacgtc 426660 cctctggggt ctccccttcc ttgagattca gtggccgaaa ggatgtcctc ctgaggtggg 426720 aagtcctgct gtcgagggac ctgttctggg aatttgccac acaggctgct tctgagccac 426780 ggggtcacct ccagggtggt agggtcttga tcccaaggaa aggagaggac accatgtggt 426840 ttcttattga ccaagtggga cctggctctg tgtgtgggag gtgtagggca agatgaggac 426900 ccaccagaga aagtacgtgg ccctggaggc ccccaggctt tgatttctgg tgtgtgcttg 426960 gagagggcac cagggtgggc acccaccatg cccagggtag gctctgcaat ggccaggtct 427020 gcattggctc ctggtgttag ggccagactc gctggttggc catgagcagg ttggttgccc 427080 tcacccgtcc ccatagtccc agtgcggccc tggggttgtt cgggggagcc ggcccgagca 427140 gtggaggtgc tgttggggcc tgcagtaggg catcttgccc cagcccagtg acccaccttc 427200 cctgtctttc caaggtttgg tggccagcag ggccaatggt gccctgtgtc tgtgatgagt 427260 cagtgttctt catggattcc atcacatggg tatcccctac ccacattccc ctcgctcata 427320 tgtgaggccc tggttggaca catgtccttc tcctgtcacc accccagatg gtgagcctgg 427380 aggaagactt gtattgggac cctacaggcc ccaggccagt gtctgtcagc ctggtgctca 427440 tcccccagtg cgctgaagct cagaccctcc ctggcaccct ggtctcctgc actgagctgt 427500 ggtgagcaca tccaggttct gctggatgca tgcatgggga gggccttgat tgggtcaatg 427560 atgagaacct tatattgtcc tgaagagagg tgatgactta aaaatcatgc tcaataggat 427620 tacgctgagg cccaggctag gtgagaattt tggaagggag cgctgggatg ccaagatccc 427680 cggcagggcc actagccact gtattttata ctgaagaact tgaggcccca aagggcatct 427740 caggggtcct agccctgtct ctgtgcccct ccgtgaggca gcccaggctc cctgtgttga 427800 cttggtgtcc aggctctgct tcctggggat agggcatgtt ggcagctcct tcctgagccc 427860 acgttctccc ctgtgtcttc tattgagctc ttctgcccag gtggggccca tgcccttaag 427920 cagtataggt gagtgtatcc tgttgcggtc atgggccata aatgaggcag tgtggggtca 427980 tcgagggtca gccttcaggc cactagcgtt ttctccaggt gcccccgggg agggaacatt 428040 gctccagtag ggtcacttcc ttgggaatct gaccctagga gcacgcattt cctgaagccc 428100 tgcaaaggtg atggtggtcc aggcaggaaa gcgttccttc agcccaacat acagcagctc 428160 ccagctgaaa tttggtgggc tcgtcaggcc ttgaggactg cccaggcttc atgatggggg 428220 acacagaagc tctggggctc cctggggctc acactggagt tctccctccc tgaagagtgg 428280 tgggtgattg ggcccacagt caggtggcgg agattcaagg aatgccccca cccctggccc 428340 tgaatgggac caactctgtt gagtaatggg ccatcttaat ggcgcctcct tgagcctgtt 428400 gggggtgggt tgctgtttca ataaggttga gtcaaagctg agctctgact gggcgcctgg 428460 tggtactgca ggccggccct tccttgggcc aagggggcag cttgtgtccc gctggtgtca 428520 tcccttcctt gaggtccagt ggtggaaagg gtagcctcct atggtgggaa ggcctgctgc 428580 tcagggacct gtcctggaaa tttgccatcc aggctgcttc tgagccatgg ggtcacctcc 428640 agggtagtgg ggtcttgagt ccaagaaaag gagaggacac catgtggttc ctgattggcc 428700 aaggctcctt ggttggccag gagcaggttg gttgccctgg cccatgcccc atggtcctgg 428760 tgtggccctg gggttgttca ggggagctgg cccaggccgt gaaggtgctc tcagggcctg 428820 cagtagagtg cagcccaggc atcttgcccc agcccagtga cccacttacc ctgtctttct 428880 aaggtttggt ggccaggagg gccaatggtg ccttgtgccc atgttgggtc agtgttctgc 428940 atggatcccc atcatatggg tattccctac ccaccctccc tgcactgata tgtgaggccc 429000 tggttggaca catgtcctcc tcctgtccct tcagatggtg agtctggagg aagacttgtg 429060 ttggaccccc acaggcccca ggccagtgtc catcagcctg gtgctaatcc cccagtgctc 429120 tggagtttgg accctccctg gcaccctggt ctcctgcact gagctgtggt gagcacatgg 429180 atgcatgctt ggggtggggg ttgcccttgg ttgggtcaat gatgagaacc ttatattgtc 429240 ctgaagagcg gtgatgactt aaaaatcatg ctcaatagga ttacgctgag gcccagccta 429300 ggtgagaatt ttggaagagg acactgggct ccccggaatg gccactgtat tttgcgctgg 429360 acacctgcag gccctgaggg ccatctggaa ggtccaaccc tgtctctctg ctcctccagg 429420 aggcagccca ggctccctga gggggcttgg tgtcgggctc ctgttccccg gggttggggc 429480 cggttggtgg ctccttcctg agcccccatt ctccccttgt gtctttcagt gagctcttcc 429540 acccgggcgg gcccccggca ttgactggca taggtgagtg gatcctgctt gtgtcatggg 429600 ccatgaaccg gtccatgtgg ggtcaccaag ggtcagcctt tgggataaga gggtttcctc 429660 agggaaccaa cctgaattcc catcagagag gtatgggttc tccaggaggg ccgctttttt 429720 gggaattgga cccaaggagg ataacttccc tgatctctgc aggagtgacg gtggtccagg 429780 caggaaagag ttccttcagc cccacccagc gcagcgttct gttgagactc agtgctcagg 429840 tcaggcctgg aggatttctc aggccatctg agggggttag aggggagctc tttgtccatg 429900 gagtgtggtg cttgaatctg cccttggggt tgggtcatgg agattcaagg atggtgcctc 429960 acccatggcc ctgattggaa ttgtccattg agaaatacgc cattccagtg ggcctcctgg 430020 agcctgatgg ggggtggtgt ttttttccct ggggttgagt cgttgatggg gactcaccat 430080 agaaagcatg tggctctgga ggcccccagg ctttgatttc cagtgcctgc ttggagtggg 430140 caccagggcc ggcacccacc atgcccaagg gcaggctctg cgactgccag gtctgcattg 430200 gctcctggca tcaggaccag cctccttggt tggccatcag ctgcttggtt gccctggccc 430260 atgccccgtg gtcctggtgt ggccctgggg tggttgagtg gagctggccc aggcagtgga 430320 ggtgctcttg gggcctgcag tagggtgcag cccaggcatc ttgcctgatc ccagtgacct 430380 gcttgccctg tctttccagg attttgtggc agggagggcc aagggtgccc tgcatccgtg 430440 atgggtcagt gttccacgtg gatcccatta cgtgggtcca tagaggatga gcatgcgtga 430500 gccagcgccc ccttcccact tcttctcatg gagctgtgag gccctgtgtg gacagctgtc 430560 ttcctcttgt cccaccaggt ggtgagcccg gaggaggact tgcgttcggc ccgctggtcc 430620 cagtgtgtcc ggaattggtg ggttcttggt ctcactgact tcaagaatga agctgcggac 430680 cctcgctgtg agtgttacag ctcttaaggt ggcatgtctg gagtttgttc cttctgatgt 430740 tcggatgtgt tcggagtttc ttccttctgg tgggtttgtg gtctcgctgg cttcaggagt 430800 gaagctgcag accttcgcgg tgagtgttac agctcataaa agcagtgtgg acccaaagag 430860 tgagcagtag caagatttat tgcaaagagt gaaagaacaa agcttccaca gtttggaagg 430920 ggacccaagt gggttgccac tgctggctgg ggcagcctgc ttttattctc ttatctggcc 430980 ccacacacat cctgctgatt ggtagagctg agtgatctgt tttgacaggg cgctgattgg 431040 tgcgtttaca atccctgagc tagacacaaa ggttctccat gtccccacta gattagctag 431100 atacagagtg ttgacacaaa ggttctccaa gtccccaccg gagtagctag atacagagtg 431160 tctattggtg cattcacaaa ccctgagctt gacacagagt gctgattggt gtgtttgcaa 431220 accttgagcc agatacagag cgcggattgg tgtatttaca gtccctgagc tagacataaa 431280 ggttctccaa ggccccacca gagaagctag atacagagtg tcgattggtg cattcacaaa 431340 ccctgagcta gacacagggt gctgattggt gtgtttacaa accttgagct agatacagag 431400 tgccgattgg tgtatttaca atccctgagc tagacataaa ggttctccaa ggccccacca 431460 gactcaggag cccagctgtc ttcacccagt ggatcccgca ctggggctgc aggtggagct 431520 gcctgccagt cctgcgccat gcgcccgcac tcctcagccc ttgtgtggtt gatgggactg 431580 ggcaccgtgg agcagggggc ggcactcgtc ggggaggctc tggctgcaca ggagcccatg 431640 gagggggtgg gaggctcagg catggcaggc tgcaggtccc gagccctgcc ccgagggaag 431700 gcagctaagg cccggtgaga aatcaagtgc agcgccggtg ggctggcact gctgggggac 431760 ccagtatacc ctctgcagct gctggcccgg gtgctaagcc cctcattgcc tggggccggc 431820 agggccggcc cgctgctccg agtgtggggc ccgccaagcc cacacccacc cggaactcca 431880 gctggcccac aagcgccccg cgcagccccg gttcccactt gcgcctctcc ctccacacct 431940 ccctgcaagc tgagggagca ggctccggcc ttggccagcc cagaaagggg ctcccacagt 432000 gcagcagtgg gctgaagggc tcctcaagtg ccaccaaagt gggagcccag gcagaggagg 432060 cgccaagagc aagtgagggc tgtgaggact gccagcacgc tgtcaccttt catcaggaca 432120 gtgtctgtca gccaggtgca cagcccttgg tgtgctggag cttgggcttt tcttggcagc 432180 ctggtgtcct gcattgagcg gtggtgagct tgtccaggtc ccgctggtta cctgcacggt 432240 gacgggggtg ccctcggtta ggttgatgat gagaacctta ttttgtctcg aggagaggtt 432300 atgtgatggg tgttgtggca gctctttgta tttcattttc ttcagtgctt tttgtgtgtt 432360 ctctttgtat tttttaccgc tttgtgtatt ttactttcac aaaggcagca gcaaatgttt 432420 tattggtggt ggtatttttc atttttattt acttcctaat ttgatagtgt tttagttgga 432480 atacacagtc tcattgtagt tgttcagaaa tatgcttttt ttctgtacat tatatgattg 432540 tgcataattt ttgccagttt tttttttaat tggggactac agttgaatgc actgcctatc 432600 tcctacttta ctgaaacaga ttgtatggaa atctaaagac gagaaagtag acaagcacag 432660 cagaggacat ttattttgat ataaccacag aaattcattg atatgacctt atcatattga 432720 tggtttttca aagaaatata aaatctttcg ataatggatt gtctcagttg cgtttctcct 432780 tatatcatgt tttgccttca atacaaattg caatgcttag aaatttaaag aacaccttct 432840 gaagtggaag atctagctaa agaattagat tggtattggc tgaaatgttg cagtaatcac 432900 atgatagggt taatacaaca tgagttacat gctgagtgct ctaaggtaga aagtaggtaa 432960 caaggaataa caggtaggta atgtaagtcg ggagaaggaa actctaggac agaatcatta 433020 gaaaaggctt gacgtcaaca gcagtgtata gaatttacag tgtatagaat ttacagtgca 433080 tagaatttac aataagtgcc tttttttgtg ctcatcaatg ctcttgctta tattgtagga 433140 ggagttagtt cccttgaaga aatatcaata caaatttcca aattgcaatg cagagggaaa 433200 aaagaatgag aaagtaaaaa atatccaaga actctggaag catttcaaaa agtgtaaaaa 433260 tgcatagtga caatgtcagg agaataagga gataaaggaa aagaaatatt tgacacaaca 433320 atgacttgag cactttctaa aattaatgat ggacagaaac ccacatgttc aggaagctca 433380 gagagcactc tgcagaataa aaatatttta caaatcgaca cctttgcatt tcatatttaa 433440 agtccagaaa atcatagact aagggaaaag cttgatagga gcaataggaa gaaaaccatc 433500 ttacctatgg agcaacaaga ataaaaattg ctttgaaatt atcttcagaa tccatgaaag 433560 caagaagtga gtcagggtga aatatttagt gttaaaagta agaaacaaaa aaaagtacca 433620 actttgaatt ttctgctcat caaaattatt cttcaaaagt gaaggagaaa tactctctga 433680 gaccaacaaa aattgctaga acttcttgcc actacaccaa ccttttaata aacgtaacaa 433740 gaaattcttc agaaaggata aaaatgacat aggtcggaaa atctaattta cataaagaaa 433800 tgaaaagcat tggagaagaa atatatgaag aaaaattaaa tatatatgta ttttttgatt 433860 cataattgat ctttcaacaa tttgttcaaa ataataacaa gattatattt ggtgattata 433920 ggttatggaa aagtgaaatg aatgacagca atattataag tcatccggtt ccaagatggc 433980 cgaataggaa cagctccagt ttacagctcc cagtgtgagt gacgcagaag acagttgatt 434040 tctgcatttc caactgacgt accaggttca tctcactggg gcttgttgga cagtgggtgc 434100 agcccatgga gtgtaagccg aagcaggacg aggcatcacc tcacctggga agtgcaagag 434160 gtcagggaat tccctttcct agccaaggga agcgtgacag atggtacctg gaaaattggg 434220 acactcccac cctaatactg tgcttttcca actgtcttag caaacggcac accaggagat 434280 tatatcccgt gcctggcttg gagggtccca catccacgga gccttgctca ctgctagcac 434340 agtagtctga gatcaaactg caaggcagca gtgaggctgg gggaggggca tccaccattg 434400 ctgaggcttg agtaggtaaa caaagcggct gggaagctcg aactgggtgg agcccaccac 434460 agctcaagga ggcctgcctg cttccgtaga ctccacctct aggggcaggg catagcagaa 434520 caaaaggcaa cagaaacttc tgcagactta aacatccctg acagctttga agagagtagt 434580 ggttctccca gtacagagtt tcagatctga gaacagacag gctgcctcct taaatgggtc 434640 cctgaccccc aagtagccta actgagagac acctcccagt aggggctgac tgatacctca 434700 tacagctggg tgcccctctg agacgaagct tccagaggaa ggatcaggca gcaacatttg 434760 ccgttctgca atatttgctg ttttgcagcc tccactggtg atacccaagc aaacagggtc 434820 tggagtggac ttccagcaaa ctccaacaga cctgcagctg aggatcctga ctgttagaag 434880 gaaaactaac aaagagaaag gacatccaca ccaaaacccc atctgtacgt caccatcatc 434940 aaagaccaaa ggtagatgaa accacaaaga tggggagaaa ccagagcaga aaaactgaaa 435000 attctaaaaa tcagagcacc tcttctcctc caaaggaatg cagctccctg ccagcaatgg 435060 aacaaagctg gacggagaat gactttgacg agctgacaga agtaggcttc agatgatcgc 435120 taataacaaa cttctctgag ctaaaggatg aggttcaaac ccatcgcaaa gaagctaaaa 435180 accttgaaaa aagattagat gagtggctaa ctagaataaa cagcatagag aagaccttaa 435240 atgacctgat ggagctgaaa ccatggcaca agaactacgt cacacatgca caagcttcag 435300 tagccgattt gatcaagtgg aagaaagggt atcagtgatt caagatcaaa tgaatgaaat 435360 gaagcaagaa gagaagttta gagaaaaaag agtaaaaaga aacaaagcct aaaaaagtaa 435420 aaaagtaaaa caaagtaaaa aagaaacatg ggactatgtg aaaacaccaa atctacgtct 435480 gattggtgta cttgaaagtg atggggagaa tggaaccaag ttggaaaaca ctctgcagga 435540 tattatccag gagaactccc ccaacctagg aaggcaagcc aacattcaag ttcagaaaat 435600 acagagaatg ccacaaagat actccttgag aagcgtaact ccaagacaca taattgacag 435660 atacaccaaa gttgaaatga aggaaaaaat attaagggaa gccagagaga aaggtcaagt 435720 tacccacaaa gggaagccca tcaaactaac agcaaatctc tcagcagaaa ctctacaagc 435780 cagaagagag tgggggccaa tattcaacat tcttaaatga aagaattttc aacccagaat 435840 ttcatatcca gccaaactaa gcttcataat tgaaggagaa ataaaatact ttacagacaa 435900 gtaaatgctg agagattttg tcaccaccag gcctgcccta caagagctcc tgaaggaagc 435960 actaagcatg gaaaggaaca accagtacca gccactgcaa aaacatgcca aattgtaaag 436020 atcactgatg ctaggaagaa actgcgtcaa ctaacgagca aaataaccag ctaacatcac 436080 aatgacagga tcacattcac acataacaat attaacctta aatgtaaatg ggctaaattc 436140 tccaattaaa agacacagac tggcaaattg gataaagagt caagacccat cagtgtgctg 436200 tattcaggag acccatctca tgtgcagaga cacacatagg ctccaaataa agggatggag 436260 gaagatctac caagcaaatg gaaaacaaaa aaaagcaggg gttgcaatcc tagtctctga 436320 tgaaacagac tttaaaccaa caaagatcaa aagagacaaa gaaggccatt atgtaatagt 436380 aaaggggtca attcaacaac aagagctaac tatcctaaat atacatgcac ccaatacagg 436440 agcacccaga ttcataaagt aagtccttac agacctacaa agagacttag actcccacac 436500 aataataatg ggagacttta acaccccact gtcaacatta gacagatcaa caagacagaa 436560 agttaacaag gatatccagg aattgaactc agctctacac caagcagacc taatagacat 436620 ctacagaact ctccacccca aatcaacaga atgtacattc ttctcagcac cacatcgcac 436680 ttattccaaa attgaccaca tagttggaag taaagcactc ctcagcgaat gtaaaagaat 436740 agaaattata acaaactgtc tctcagacca cagtgcaatc aaactagaac tcaggattaa 436800 gaaactcact caaaaccact caactacatg gaaactgaaa aatctgctcc tgaatgacta 436860 ctgggtacat aatgaaatga aggcagaaat aaagatgttc tttgaaacca atgagaacaa 436920 agacacaaca taccagaatc tctgggacat atttaaagca gtgtgtagag agaaatttat 436980 agcactaaat gcccacaaga gaaagcagga aagatctaaa attgacaccc taacatcaca 437040 attaaaagaa ctagggaagc aagagccaac attttcaaaa gctagcagaa ggcaggaaat 437100 aactaagatt ggagcagaac tgaaggagat agagacacaa aaaacccttc aaaaaatcaa 437160 tgaatccagg aactggtttt ttgaaaagat aaacaaaatt gatagaccac tagcaagact 437220 aataaagaag aaaagagaga agaatccaat agatgcaata aaaaatgata aaggggatat 437280 caccaccaat cccacagaaa tacaaactac catcagagaa tactataaac atctctatgc 437340 aaataaacta gaaaatctag aagaaatgga taaattcctg gacacataca ccctcccaag 437400 actaaaccag gaagaaggtg aatctctgaa tagaccaata acaggctctg aaattgaggc 437460 aataattaat agcctaccaa ccaaagaaag tccaggacca gagggattca cagctgaatt 437520 ctgccagagg tacaaagagg agctggtacc atgccttccg aaactattcc agtcagtaga 437580 aaaataggga atcctctcta actcatttta taaggccagc atcatcctga taccaaagcc 437640 tggcagagac acaacaaaaa agagaatttt agaccaatat ccctgatgaa catcgatgca 437700 aaaatcttca ataaaatact ggcaaaccga atccagcaac acatcaaaag ctaatccacc 437760 acgatcaagt tggcttcatc cctgggatgc aaggctggtt caacatacac aaatcaataa 437820 acataatcca tcatataaac agaaccaaag acaaaaacca catgattatc tcaacagatg 437880 cagaaaaggc ctcgacaaaa ttcaacagcg cttcatgcta aaaactctca ctaaactagg 437940 tgttgatggg acgtatctca aaataataag agctgtttat gacaaaccca cagccaatgt 438000 catactgaat gggcaaaaac tggaagcatt ccctttgaaa actggcacaa gacaggaatg 438060 ccctctctca ccgctcctat tcaacttagt gttggaagtt ctggccaggg caatcaggca 438120 ggagaaagaa ataaagggta ttcaattagg aaaagaggaa gtcaaattgt ccctgtttgc 438180 agatgacatg attgtatatt tagaaaaccc catcgtctca gcccaaaatc tccttaagct 438240 gataagcaac ttcagcaaag tctcagaata caaaatcaat gtgcaaaaat cacaagcatt 438300 cctatacacc aataacagac aaacagagag tgaaatcatg agtgaactcc cattcacaat 438360 tgcttcaaag aataaaatac ctaggaatcc aacttacaag ggatgtgaag gacctcttca 438420 aggagaacta caaaccactg ctcaacgaaa taaaagagga cacaaacaaa tggaagaaca 438480 ttccatgctc atggatagga agaatcagta tcgtgaaaat ggccatactg cccaaggtaa 438540 tttatagatt caatgccatc cccatcaagc taccaatgac tttcttcaca gaattggaaa 438600 aaactacttt aaagttcata tggaaccgaa aaagagcctg cattgccaag tcaatcctaa 438660 gccaaaagga caaagctgga ggcatcacac tacctgactt caaactatac tacgaggcta 438720 cagtaaccaa aacagcatgg tactggtacc aaaacagaga tatagaccag tggaacagaa 438780 cagacccctc agaaataata ccacatgtct acaaccatct gatctttgac aaacctgaca 438840 aaaataagaa atggggaaag gattccctat ttaataaatg gtgctgagaa aactggctag 438900 ccatatgtaa aaagctgaaa ctggatccct tccttacacc ttatacaaaa attaattcaa 438960 gatggattaa agacctaaat gttagaccta aaaccataaa aaccctagaa gaaaacctag 439020 gcaataccat tcaggacata ggcatgggca aggacttcat gactaaaaca ccaaaagcaa 439080 tggcaacaaa agccaaaata aacaaatggg atctaattaa actaaagagt ttctacacag 439140 caaaagaaac taccatcaga gtgaacaggc aacctacaga atgggagaaa atttttacaa 439200 tctactcatc tgacaaaggg ctgatatcca gaatctagaa agaagttaaa caaatttaca 439260 agaaaaaaat caaccccatc aacaagtggg caaaggatat gaacagacac ttctcaaaag 439320 aagacattta tgcagccaaa gacacatgaa aaaatgctca tcatcactgg ccatcagaga 439380 aatgcgaatc aaagccacaa tgagatccca tctcacacca gttagaatgg caatcattaa 439440 aaagtcagga aacaacaggt gctggacagg atgtggagaa ataggaatac ttttacactg 439500 ttggtgggat ggtaaactag ttccaccatt gtagaagaca gtgtggcaat tcctcaagga 439560 tctagaacta gaaataccat ttgtcccagc catcccatta ctgggtacat acccaaagga 439620 ttatatatca tgctactata aagacacatg cacatgtatg ttcattgtgg cactattcac 439680 agtagcaaag acttggaacc aactcaaatg tccatcaacg atagactgga ttaagaaaat 439740 gtggcacata tacaccatgg aatactttgc agccataaaa atggatgagt tcaagtcttt 439800 tgtagggaca tggatgaagc tggaaaccat cattctcagc aaactatcgc aaggacaaaa 439860 aaccaaacac tgcatgttct cactcatagg tgggaattga acggtgagaa cacttggaca 439920 cagggtgggg aacatcacac acgagtggct gccgtggggt ggggggaggg gggagggata 439980 gcattaggag atatacctaa tgtaaatgac gagttaacgg gtgcagcaca ccaacatggc 440040 acatgtatac atatgtaaca aacctgcacg ttttgcacat gtaccctaga acttaaagta 440100 tgaaatatat atatatatat atatatatag tcatgaggga gagaaaatac tcttagttac 440160 ttggactaac ccacgaagta ggacagtata atttgaaaaa ggacttggat tagttgtaaa 440220 cgtataatgt aatatccagc acagccacta aaaatgattt tgaaaaaagc agtataatca 440280 atatactaac agaagaaaaa gcagaatcag gccagacatg gtgactcatg tctgtaatcc 440340 cagcactttg ggatgctgag gcaggaagat cacttgagcc ccggagttca agtccagcct 440400 ggcaacgaat aagagcccat ctctaccctc cacccccccc aaaaaaaaaa agaaaaagaa 440460 aaagaggccg ggcacggtgg cttactcctg taatcccagc actttgggag gccgaggtgg 440520 gtggatcgcg aggtcaggag atcaagacca tcctgcctaa cacggtgaaa ccccgtctct 440580 actaaaaata caaaaaaaaa aaaaaaatag ctgggcatgg tggcgggcgc ctgtagtccc 440640 agctactcag gaggctgagg caggagaatg gtgtgaacct gggaggcaga gcttgcagtg 440700 agccgagatt gcgccactgc actccagcct gggagacagc cgcaagattc tgtctcaaaa 440760 aaacaacaac aacaacaaaa aaaaacaaaa acaaaaacaa agaaaacgaa aagaaaaagc 440820 agaatctttt tttttttttt tttttttttt tttttgagat ggagttttgg tcttgttgcc 440880 cgggctggag tgcaatggca cgatttcagc tcaccacaac ctccacctcc caggttcaag 440940 caattctccg ggctcagcct cccgaatagc tgggattaca ggtgtgcacc accatgcctg 441000 gctaattttt tgtatgaaaa agcagaatct tatacaatgc tcaattaaaa tcagggagag 441060 gagaaaaaga gtagaatacc aaaaaagtaa caaattacaa ggttgatata aatagaaaac 441120 aatcacaaat actgagtata ctaatctaag tatatcaata atcactttaa acatcgctta 441180 aaagacagag attgtcagtg gattaagaac aagacccaaa tatatgttgt ctatgagaaa 441240 tgcactttaa atagctgggc atggtggtgt gcacctgcag tccttaggag gccaaggcgg 441300 agtgtcacct gagcccagga ttttgggact acagtgagct atgatcatgc cactgcactc 441360 tagcctggtt gacagaataa gacctcatct ctatagaaaa aagtaagtaa atctacttta 441420 taaaggcaca aatatattca cagtaaagga atagagaaag atatcccatg ctaacattaa 441480 tcaaaataaa gtgaaatagc catattaatt tcagacacaa ccgactttag aacaaggaat 441540 attatcagag atcaaaaggg acattcctta atgataaagg gatcagtttt ctaagaagac 441600 ataacaatcc ttaatgtgta cgcactgaac agcagatcat caaagtacat gaagctaaat 441660 ctgatagaac tgcatagaga aatagataaa ttcactctta gagttggagg cattggcatc 441720 cctctatcag aaatggacag gtttagcaag cagaaaatca gtaagggcat aacatgatca 441780 atcatgatca aaaacttgat tcagtcaact atatgtaact gacatctatg gaccacttta 441840 cccaacaaca gcagatgaca cattttctca cacacacatg aaacattcag cagaatagac 441900 cacattctgg gctagaaaat gcacctcaac aaatttaaaa gaatagaaat catacaaagt 441960 atgttctcag actacaatgg aatgaaagta aacaaaaatc actaaaaaag atagctgaaa 442020 aacatgaaaa tacttggagg ttaaacaaca gactgaaata actgaaggtc acagaagtct 442080 caagataaat ttttaaaata tttcaaacta aatggaattg aaagcacaac ttatcaaaaa 442140 tttaggaacg caacaaaggc agtgcctact gggaaattta taccactgaa tgtatgttaa 442200 aaagaacaaa gatctaaata aataatcctt cccattggaa agctaggggg aaaattcaaa 442260 ttaaattcaa agtaagcaag taaaagaaat aataaaatat gaatacaatt ctgagtggcc 442320 tgatatctga tttctggaag ctgagtttta tgtggcttta gaagtttcat gttatgagtg 442380 tgaaatggca agtgaccatg gcgattgctt ctgatatggc cacctcaatt acatagagaa 442440 gggatgatca gtggcatcat cccagttctg catgatacca caccagtgat tctccaaagt 442500 caagaaacct gtatatgttg tccttgtgtt tggtgaatct gtggtctata gactacataa 442560 tgggctattt ctggggtact gaccattttg ctccattaag gaaaaccatg catgagccat 442620 ataactatgg gaaacaatgt tttccttttt gacacctggc ctactctctt cttaggtgag 442680 agcaaaggaa gagcaccact tggcctgctg cacccagggc aatttatacc atccagatat 442740 ccagcactga atatgtagca actccaatcc accatagaac attaatctat ctctgataag 442800 catgctaata tctatgattc tgcctttgtg gggagatgac tccatagatt aaccccctgg 442860 cttggggcaa tatggagatg ttatattgtc ttcgacaggg aagatgacat aaaaattatg 442920 ttcaatagga ttatgtggag acttaacata agtgacaaac ctaagacaag aagttagaaa 442980 tccttgtttc ttttaggtga ataattttgg agcttgagaa aaagacacca ttgtggcgaa 443040 cttgctttgc caaaccctgt gtatgcattt ttgggtaaac aacacatttt catcctttaa 443100 gcattgtttc cattatttat aattcctaat agtatgagac atttaggact cattccttgg 443160 ttcttcttct ctcattgtat ctttcattgt atctttcagt gctgcaagag atgcaatcat 443220 cccattaatg aaagcagagt gactgccttc gtcacacata cattcaaaat agatcactag 443280 gctagtgatg attctctctt aaggctatta tgtttactca tttaaaaaat ctggatctca 443340 gtatagattt tcttctcagt gagtgactga cctatctgat atgatgctat gacaaaatct 443400 ttacttttta cctgaatttg gtgggattga aagttgagaa catattaatt tattttctgt 443460 ttcacttgat taataatgcc caatctaaca tgcagtgttc acttgggtac atatatacaa 443520 ctacatcaaa ttttttcttg ttttacctta aaagtgttaa gatattgtaa tggtatggcc 443580 agtttactca ctggtaaact tttcataaca gaaatatcat gccagtggac acaaatatgt 443640 aacatcagta atttgctttc ctcatgaaac agagaactga ataagttgat gggtaaacta 443700 gtatctgaat tataaacccc aaatatcatg tgacttcatc attttcagta taatgaaaat 443760 acaggctgtg aatgcttcca gttggtcctg aaagggcctt tgaggtgagt aggttcacca 443820 aagcggcaac atatgtgtcc cagtgggcat tctactcctc agtaagtgac ttgacattct 443880 ttatggcttc ctcatgatta aaacaagtct ttttattgaa attttactga aataatgatg 443940 aaacaatgta atattctttt catctacata taagagtaga catagattaa cctctacctt 444000 tttttttttt ttttttgaga cggagtctcg ctctgttgcc caggctagag tacagtggtg 444060 cgatctcagc tcattgcaac ctctgcctcc caggttcaag cgattctcct gcctcagcct 444120 cctgagtagc tgggattaca ggcacgtgct accattcctg gctaattttt ttgtaatttt 444180 agtagagaca tggtttcacc atgttggtca ggctgttctt gaactcctga ccttgtgatc 444240 tgcccacctc tgcctcccaa agtgctggga ttacaggctt gagcccccgt gcctggcctt 444300 cacctctacc tattataata ttttcatgtt attccatttt gtcatgtttg tgggtcattt 444360 gatgagggtt cacaatatga aaactgggca ttttggccaa gatgcatgta aatgaataca 444420 actccatgtg ccctgataac tgatttctag atcctgagat gcaagtggct tccagagtgt 444480 ctgtatttta tgaaagttca tatacagtaa accatgctaa ttgttactga tacagcttcc 444540 ttgaatatat aaagcgatga ttaatgggat gttttgtttc tgcagaaaac cactgaattg 444600 cttctccaaa gccaagtgac ctgtatgatt tgtccttatt atattttgtg aaccagtgga 444660 ctaaaacctt tataatgggt cattttttta gtattgtcaa tattgctcaa ttaacaaaca 444720 tgactcatat acacaggtga gatgtagttc tccctttgac atttgctcta catctgtccc 444780 ttagatgatg atatggaaga aaagcactct ttggcctgtt gtgactggga cagttgacag 444840 cacccaggtg tcctttaatg aaaatgctct tgacaccaat gcatcctagc atcacagctt 444900 caggaagcct tctcaagtgt gcatggggag tactatgtct ttcatcaata atgaaatctt 444960 ctgatttggt gagaaataat gccttaaaat tacactcaat aggattatgc tgaggctcag 445020 cctacctaga tgaaaatgct gaaacagata atagtgactt cttatttccc ttcaagggga 445080 attttatttt gaacttgaaa taacaaaatc tttatgggta acttgtttgc ccaactgtat 445140 cagtgcacct ataaatgaac aaaaaattct cagcctataa gctttgcttc agtgaccttt 445200 aatttctaat agtaaggtat attcaggtct cattctttgg ctttttctct tattgtgtat 445260 ttcagtaaga catgctgcca agagatgtgc cattctatta taaaagatca gtagcttcct 445320 ttaccgacgt gtatattcta tctagaacat tgagctatgg aagactccca cctaagggaa 445380 ttagttttac accttcaggt aatctgaact tcaatatgag ttttgcttta tgatataatc 445440 cttatgacaa aatctttact ttttatctga acttcataca atcaatattg aagatttttt 445500 aaattcactg ttacctagtc caatatttaa tatacatttg gctgtagata catgactaga 445560 caaaaatttt ttatattatt attgtggggg ctctaacagt gtttcactgt tttgagttac 445620 tgatgaactt tctgtaactg tgagaccatg gtaatggaag agaccgtggt aatggggagg 445680 agaatgtgag gatcagtatg tactttgcct ataaaactta aatatttagt aatttgatca 445740 ccaaattgat actcaaattt cagttcctat catgtgtaaa ccaaaaagta tctgagattt 445800 agaagtttat ttagaagtgg attttgccaa ggttaagcac atgctcagaa gaaataaacc 445860 caaaatcaca gaaaccgtct ggggtctatg tctttctcca aagatgattt tgagggcttc 445920 agtgtttaaa ggggaaaagt gggctggagg gggaaaaggg agggtatgat aatccgtatg 445980 ttccaagaca aaaggagcag gtaggggtat agtcaataat gtattcatct catgctcagt 446040 aaatcagcac tttacataag ataaggtgaa catagagaag ctacctgtgg agatctttaa 446100 cctttaatct gtagctatct gcttaagatc aaaaggaaat tcttgcatga ctcagctttc 446160 agcttatttt ttttttctct tggcgtagta aattggggtc ccaagtttat tttcctttca 446220 cacatgtgac cccactattt tcagaataat gaaagcacat gttagaaatg atgacactta 446280 ttcctaatat ggactttgaa atgactgggt tcacaaattt agaatcatgg atctcattat 446340 aggtttttat tttcaatgag tgactggcct acttgatgga attctttcaa aaaatgttca 446400 ctttttactg agattatatt aaaataatgt tggaatgtgt tcagtcatgt ttaccatctc 446460 tatagtatga tatatgataa tatcgcagat tactcagtgt caaaaacctg gcataccttg 446520 tccttatgat gttgatgagt caatggtcta gagccttagt aatatgtctt tttgtggtag 446580 tacggaccgt atctgtccac taagaaatag cctgtgtaag ccatatacac atgaacaatt 446640 tatgtctgat tttgaactat ggtcccattc ctatgcctgt agataaagac tgctgagaag 446700 agcaccctct ggtgttgtca cagaggcaag tgctaccgca caggcatgct gcagtgaatt 446760 taactgatcc tctgtccctg caaccgttgt ttaaggatgc tattctggta agggtttaca 446820 agacaacgta aatatatgta taaagagtat cttcaggaga cgtaataatg taaaaatcat 446880 gctcaataga attaagctga ggctcaaaat agtgccaatc cttgcaagaa ggtgtgagaa 446940 gtcattagat ttggggggta tgggttattc cattttgaac ttggtaggaa gaaacccttg 447000 ggggaatctt acatcatttg cctctaccta cttctaaagg aacttttaaa attcttttat 447060 cttgtcttta ttcttaatac tcatacatta ttagagagaa tatcttggtt tattttttcc 447120 tcatggtgtg cttcagaatg ttcatccagc aagaggtgtg tcattacacg gattatatat 447180 atgagttctg tctttcgtaa ttaaaaaatt tcaagtggac catttgaata ttaaacattg 447240 gccttcaaaa tgattacatt tacctgttca tacaaaatta gtgagcaatg atctattctt 447300 tccaatgagt gactgatcta atgaggtcct cattaaaact cctttttttt tttttttttt 447360 ttttgcctga acgtactttg atttaaagat gtgacattta gtaattcatt gcaatcaact 447420 ctttagtgat tgcacaaata gacaatcctt ttctattatt ttattttttg gttgctgtgt 447480 atggtgttat gatgtttgtg gatcattgag gcactactca caactgaaag actttggcaa 447540 ttttagggaa tggcttgaga ttcagctata ggttaccctt gattgaaatt gaatacaata 447600 caggtagtct gaaatctcat ttccttatcc tgagtctcac tcaggtgtca ttagattcat 447660 tataaagaaa tgcatacact atgtatgatg ccagttgtta ctgatatgaa gacgataaga 447720 agcttttatt tctgcaggga aataatccct taccaggtca tcaaaagaca tgatacctat 447780 gtgcttggcc cttactgtac acggggaatc agtggtctac cacagcttaa gtaacgggtc 447840 atatttggag tatcacacat ctcagtcttg tagaaattag gaacagcaat taggagtcat 447900 gcacatataa gagatgtaat cccacccttt gactatagcc tactcttgtc ttttacagaa 447960 aagactgtgg aggaagaaaa ccctttaccc tgttgttcag ggagaaactg acaccactca 448020 actgcctggc actgaaaatg tggcatccag tccactttac catcagtgtt taaggaaacc 448080 atctctggta agcatatttg atccaagtgt gcatatgcac atgagtgcca tgggctgggt 448140 caatgatgag atgttacctt gaagagaaat gatgacgtaa aaattaagtt cagttggatt 448200 acgctgaggc ccagcctagg taacaattgt gagacaagaa gtttggattt cttagtttcc 448260 ttccattggg gactttattt tgggattctg gcaatggaat cttattgcga aacttgtttt 448320 gcacgcttct atctgtgtgc ttctaagtaa actataaatt ctgattcttt aagtgctatt 448380 taagtttcct acaattccta attttcttgg atatttggca ctaagaccct tgctcttttt 448440 ctctcattgg atgatttagt aagtcctact ggcactattc tattgagtgg aggtgagagg 448500 ctgcctttgc tgactgaaaa atttcaaata gataattgaa ctagtgaaga ctgagctcta 448560 taataattag atttattcat tcagacaaca tgaatatcac gatagggttt tcttctcaat 448620 gattgactga cacatgtgat gcaatcctca tgagaaaatc cttacttttg ccctacgatt 448680 gattgttttc agggttgaga aatatgatac attggaattt tgctcaatgc gctacagtta 448740 tcgtggtcta aatatacaga caaaattttc tgtaatgtta gtataatatt ttaacagtgc 448800 taggatatgt tttgatcatt aatgaatctt tatgacttaa gggtccttgc aattgggata 448860 aaaatgtgag tttcaataat atgtgtttgc ccatgaaact tgaaattaga taaattgatg 448920 agcaatctgg tgcctgactt ttctttctca agtacctttg gcttcgtttt cattatgatg 448980 aaagtgtgtg ctgtgaataa tgccaatggt aaataagacc tttatggaca cttatatgaa 449040 tgacagtcag ggccgttcct tcaggccaca tgattatcgt tatgcattct tcttctcaat 449100 gagtgactag catacttgcc aggatctaca agagggaaac tttatttttt actaaaattg 449160 catcgatata atgttgacaa gttttgtgat tattggtatc atctctaaga tgtgatgctc 449220 atttggtcta aatatagaag ttaacatatt aacttctaat ttatatatgt caggttgcta 449280 tgtttttaca atgtttgtgg tttattgatg atgactcaca acataaagac tatggcatta 449340 tggctacatg ttctaattct gatatataca tatcccatca ttcattaaat taaatacaat 449400 tatgagtagt atgatgtctg ttttctaaaa tctgagtttc acctggctcc agtatgatca 449460 ttatatgatg gagtgcaagc aacatgttaa tgccaattgt tattgatatg gcttccttga 449520 atatgtaaac aagactgatc aattgaaggt cttatttctg cattaaacta cctgagatat 449580 tctccaaatt caagagacct gtatagttag tctttattct gtttgatgaa taaatggcct 449640 atagcctatc taatggatca gtttttccag tactaatcat atctcttcat taagaaatag 449700 catgcataag ccatacatac aggaggtaat atttgtcatc ttgatctact gtcttatcct 449760 cctcccctta gataaggatg actgaggaag agtactcttt ggcttgttga caccagcaca 449820 gctgacacac ccagatatct gtttggtctc ctgtgaactt tcaaccagga tttaaggatg 449880 ccactctggt aggtattttc agacaaagtg aatatgtgat tgtagagttc catggcttgt 449940 ttcaacaata agaccttatg ttgtcttgag gacatgagat gacatgaaaa ctagactggc 450000 tggtccttat cttttctggg gtattctagt ttgagcttaa gataaagaaa tatatttggg 450060 atatagtttc tctcacctgt ttctattagc ttctagaaga ccacttatca attctttcct 450120 cctgatttag tggaaaacat tttggcagtt cctcaaaaag ttaaagataa aattaccatg 450180 taacccaaca attctgctcc taagtacaca ctcaaaagaa ttgaatacaa atgttcaaat 450240 gaatacatac acatgaatgt tcatagcagc actattcact ggctggagtt ccagaccagc 450300 ctggccaacg tggcaagacc ctgtctctac taaaaataga aaaattagct gggcatggtt 450360 gctcacgctt gtagtctcag ctactcagga ggctgaggca caagaatcac ttgaacccag 450420 gaggcagagg ctgcagtgag ctgagatcac accattgcac tccagcatgg gtgacaagtg 450480 agattctgtc tcaaaaaaaa aaaagtgaag gtatgatgac aatgtcacac aaaatagtga 450540 ataccaataa aaagatagaa attattaaaa agaaccaaat gaaaattctg gagttgaaaa 450600 gtacaataac taaaatttaa aaatttatta gaaaggctca atagtagatt tgaactggga 450660 gaagaaacaa gaagtaaact tgaagataga acaatagaga ttatgttcaa aagaacagaa 450720 agcataaaga ataaagaaac aaagagagtc tcagagaatg tggaacatca ttaagcatac 450780 cagcatacac atatgggagt accagacagg caggggagat acaaaggatc agaaaaaaat 450840 atttgaagga ataatggctg aaacctccca tatttgtgga aaacaataac tgacatatcc 450900 aggaagctca atgaattcca atgaataaat gcaaagattg acaaatggaa acatcacagt 450960 aagatatctg aaagtcaaaa acaagaagaa agtcttgaaa gcagtgtgag aaaaatgatt 451020 tgttacttac aagggaaccc caggaagatt aacagctgac ttcagcagaa gcaatggagg 451080 ccagaagcaa aggcataaca tattaaaaat gctcaaagaa aaaagaacct gtcacctaag 451140 aattctgtac ctggcaaagc tgtctttcaa aaatgaaggc aaaataaaga cttcctcaat 451200 taaaaaaaaa aaagttggag aatctactgc tctcaaaacc cccttaaaag agttctctaa 451260 atacttaaag aagttattca agctgaaagc aagtgagcct aggtagttat tcaaatcaac 451320 aactacaaag caaatgcttg taaaggtaat tatataaata taaaagacag tagaaatgta 451380 atttttctct gaagtgattt taaaataaat tctataaaat aatatgtata taatgtattt 451440 tggggtctat aacatataaa agtgtaatat atttgccaaa gaagataggt ggatgcaaag 451500 caatacaaga ctaaggaaat gactacagat ggtagattaa tatttattat aatgtctttc 451560 ttggcttata gcatcaataa atgtaatatg tataataata ccacaaaaga tggcaaaaag 451620 ggaatagagc tatataggtg taacatttct gtataagact gaaattaagc tagtgtaaat 451680 tagaaactta tttgggtgag ttaagatata tgcagtaaac cctagagcaa ccactgaaaa 451740 aattcaaaac atatagtgaa aaaaattatt aaggaagttt aaatgctaca ttataaaata 451800 attacttaat gaaaaagaag taaagaggaa tagaggaaca aaaacacatg agacacagag 451860 gagaagaaga atgacataat aaactcaact aaataataaa attacatgtg aatacagtaa 451920 atatgtaaat taaaaggcag agattcccag gctggataaa atctccaggt ttaatatccc 451980 tttgccccaa ataaactcca gctttttttc ctatgatgta tttgatcatt gtgctggttt 452040 acaaaagatt tctaaccttt ctaaaatctt taaaatcagc ggcgaagtgt tctatctcat 452100 ttcacccata tatatcagag actcaaatcc tgaaaaatac caagttgacc tgcccattct 452160 tgagttctgc tgaatggtgt gttcccagat cactatggat attgctgttt acttgaccaa 452220 ttacttttag tcaacaagat ttgaacaatg cttttgattc acacagcgtg agacctagac 452280 ttccctcata ttgaaatagg agcattagca tcctggattc ctgcaccggc ttttgaacct 452340 tatgtttcct gcaccccaag aagccatgtt atctggacat tgtcctctct gtgatgggaa 452400 agaagagttt tttcaacaaa tgttgctagg acaactggat atctagatac aaaagatact 452460 gcatttatgt taccagtttt ctgtgtcagt ccattttgct ctgatgtaac agaatactgc 452520 agactgggta tttgtaatga gtggaaactt attggctcac atttctggag gctggaaaga 452580 tcaaggggct ggcatatgat aagggccttc tcactctgtc atcctatggt agaagggcaa 452640 agagagggta tggatgggac aaatatcttc ttttatagga acccacccct gaaataacag 452700 cattaatcca ttgatgaggg cagagctctc acagcctaat cacctttttt tttttttttt 452760 gagacggagt ctcgctcttt cgcccaggcg agagtgcagt ggtgctatct cggctcactg 452820 caggctccgc ctcccgggtt cacgccattc tcctgcctca gcctcccgag tagctgggac 452880 tataggcgcc cgccacggcg gccggctaat tttttgtatt tttagtagag acggggtttc 452940 accgtgttag ccaggatggt ctcattctcc tgacctcgcg atccgcccgc cttggcctcc 453000 caaagccctg ggatcacagg cgtgagccac cgcgcccggc cgcctaatca ccttttaaat 453060 gttgctttat taaacactgt tgcattgagg gttacgtttc caagacaggc ttttgaagtg 453120 aaatgaaaaa tttgaccatt cccaattata gtttgaaatt tcaatgctcc tttcttagta 453180 tgtgattgaa catggataag ataatcagta acggtggatg taagaacact attaaccaac 453240 ttgactccac tgtcatatgt agaacacaac acccaacaat agcagaatgc acattatatt 453300 caagtgctca taaagcatta ttttgtatat atgtattttc tccctttttt gataaagtta 453360 gctagtagag tgcctatgta gttaatattt tttaaaaacc acaggcttct caattattaa 453420 ttacatctat ggtttttaaa atattatctt cattaatttc tgctttgatc cttattcctt 453480 tctttcttgt actttctttt atttttgttc ttttttagtg ttttaagatg aaaattgaat 453540 tgtttcattc atctttttca ttttttaaaa taaaaacatt tagtgcaatg aattttcctc 453600 tagaactgcc tttaaatgca tattacagat tctcatatgt tgtatatttt aaaataatat 453660 gtaaatatat atttgcatag aaaaacatat ttacatacaa aatatgtatt tacatattta 453720 aacatatgta ttttctgttt atatttttcc ttttactcag gagttaatag gatattttta 453780 aaatttcttg gtgaaagcgc ctttatctta ttgttagtaa agtctatgtt tttgcattgt 453840 gatcagatag tgcagttttt aatatttctt gagttactaa tttttctttc caacctaata 453900 tataatcagt tttttgtgac tatgccatgg gcacttaaga acaacacaga tcttctatta 453960 tctgtcaagt ttaatatgta gccataaaat ctaccttatt tttatgttgc tatttttgcc 454020 cacttgatct gtctttttct gataatggtg tattatagtt ttctattatg ggatcatcta 454080 tgtcttgtct ccttacatct catacatctc atgcagtttt ttattcataa aggtggttat 454140 tatgttattt ggtatataag tctccataag ggtcaaatct tcatgtgtat tatatctttt 454200 agcataaaaa aagtgtcctt ctttgccttg attaacatgg tgggacttga atacattgtg 454260 tgatataaga attactacgc ttgcatgcga ttggcatgaa aaaaaaaaag attactccta 454320 tctctttttg ttttcatgtg cctgatatac tttcgcccat ccctttattt tcagtctttt 454380 agaatccatt tgttttagat tcatctctca tagaaaacat attatgtttt attttgtgag 454440 cccactgaaa atatttttct tctagtaggt gtgtggagtc cactcacgtg tgtgtgtgtg 454500 tgtgtgtgtg tgtgtgtgta gctatgactg atatttattg tgtttgtatt ttctttatat 454560 ttgctacgct cttttgtcac ggtgtagtct ttgcttgcct atttattcat acttaggaga 454620 gtttttgttt ttgttggagt gtttactttt gtacctctct taattctgtt agttctgtgt 454680 tttcctagtt aatcttttac ttctgattta tcagtttggg ggatgttctt cagcactccc 454740 ctattctcat gcaaagtgct ttcggttttc ctcttttttt ttttttcctc ctcctgtgtt 454800 tagttgtctt atttctactt tgtcacaata ttagtgacat ttgtatgcta gtcttctacc 454860 ctggataggg aatatacacc tgtcagatgg aaggaatatc atgttgtatg ctgctgtcaa 454920 atagatccta acatacttta ataatctttt aaatgatata atccaagttc atagttaact 454980 cctgactttt tatttctatc atattcagta gatatatcag cattgacagc catcccactg 455040 caatatcact tcacattttg cttagaccaa agggttctga gaagcttctg gagctgttgt 455100 gaaagccagt ttcattaaag tcaagtcaga catccacctg tgctgttttc tgctataagc 455160 tgaatgcagg ggatacaatg ttaggagcat cagtgtggta tgaggaatgt ttacttattg 455220 gtagtagact tgtctggatc aaggataagt acaagtatct gagatgctga ggtgtggctg 455280 aatgaatggc catctgttct attgcaacag gataaataac acattcggag caggcctaac 455340 tggtgaactc ctcaattatc tcacaatagc actatcacgt gtctttcatt tttcacagca 455400 cagtgtattt tcataaaatc tttattggta gaccacaact ttagcatttc ccattcaaga 455460 tacaactact gtgtcacttg gatagcttgg tagagaggaa attggctatt ttcagagtaa 455520 agaattcaag gaggaaacag attataaatg aaatgacaaa ggtgatgaga tcaagcaatg 455580 ctgacgtttg tagcaaggag tagagggctg agatgcctgt atgataagaa attataatgg 455640 aaccaatctt gtgctttatt ttttattaat ttggagcatt ctctgatctg atttattttc 455700 tatgtgatat tttgctgcag gttaaaagct gaaacaactt caaggaaact tcagggaaaa 455760 gaggtgagca gccactttgg tacttttgaa attctttgtt ctgtgggcaa tgatgtcaga 455820 atgtcaaaga ctgtgagttc attatttcag aggcttaaag gagattattc ttttggtaga 455880 tatatttccc catgggtgtc cctaccttgt tcaaggattc cttattattg tttcttctct 455940 ttgtttaaat ctctttttga gatgacctaa acaactgtgg agaatcattg atatatttcc 456000 ttttttcact gttcatgttg ggtgaaaata atcttgtagt gaaattcaca tgttctaaat 456060 attgtttttt tacatcttta tctggcacat tcataacata gatgtttcta tacatattag 456120 tactgtaatc ataccatata ttattctgtt accccactta ctccttaaac ttttagttaa 456180 ttaaagagtt tttataaagt cccccaatag attttttttt tttgagacat agtctcactc 456240 tgttgcccag gctggagtgc agtggcgtga ttttggctca ctgcaacctc cccatcctgg 456300 gttcaagcaa ttctcctgcc tcagcctgcc aagtagctgg gattacaggt gcctgccacc 456360 acgcccgact aatttttgta ttttcagtag tgacagggtt tcaccatctt ggccaggctg 456420 gtcttgaact cctgacctcg tgatccaccc gccttggcct ctcagagtgc taggattaca 456480 ggcttgagcc actgcacccg gccagatttt aatctaattt tattagaaca attcagtcat 456540 atgttttttc atgctatgta tatgagagtt ccattattca gatactaaac aaatgtctac 456600 tgtacattta ctgttctcac tgatgatgca ttagataacc atgcacaaaa taagcctggc 456660 tgtggaaacg cttatttgtt gggagggtgc ttgtttggat cgatgatgag aataattgtc 456720 tgaggatgct gagggactca ttccagatgt caatctgagg tccagatgtg cggccctcca 456780 ataggacaaa taagactctc agagcctggc tctatttggg gatccctcag tgacaacata 456840 gtacccctgt gagcgtgcct tttctatctc ttcgaagagg gcagtggcat cctgtcttat 456900 gagtcagtgt gcactttagt gtgcctagtg acccaagact tgctttaatt gtagatagat 456960 acttacatat aggaaatatt tcttaagtaa caaatgaaaa actttagaag attgaattaa 457020 gggtcaagca actgtgatat gtctgaaaat ctcattagtg ttgtgctgaa agaaggaaat 457080 atggcatgcc tctattaaat aatgacagtg gaaccaagtt tattgctttg ttatttttac 457140 tgtggagtat tttctaagat tatttttgct ttttttttct ttcatgtttt gctgagatag 457200 aaggcctgga atctgatcct ccacttcaga gaacaggggt gagtagctaa gccattatct 457260 tttgaaattc atatgtcatg tgctctttgc taggtcttta ggtcgttttg tacatctttt 457320 cagaagctta ttggaggaca ttttcatgat atgtcctttt cctcattgag accctcacca 457380 tgtcacctac actattgaat ccttatcatt tctcttttaa ttttaactct cttttgcttt 457440 tatggaaaaa tgtagaattt aagagaattt ttggcaattt catattggat caaaatgtat 457500 tgtagtgaaa tccaggtgtg ccaaaatatt aacagatttt ccccatctgt ttaattattg 457560 gggtttcaga atagagactc catggttcat aatatctttg tggtcatact acattatatt 457620 tctgcttcta atttaattat taaatattga cttgaattag tcttttcctc attgttgcaa 457680 caaggtaagt tatataggaa attttcttct cttgatggca tgtctgagat aatcatagat 457740 ataagacacc tggctggttt ctagaatgca tgtaattttt atttcttgat ctgtgtgttg 457800 agtacttgct gtgattgcat catgcaaata cattgagctt tacaatttta gtgtatgcac 457860 ttttctacat gtatattatt cttcgataga aagtaaaaaa aacttatcga actagtcaaa 457920 atattggtta atacataaaa aaagtctcaa gtagattgtg tattacatgg tgcttgttga 457980 ttgatgccct cataatagat caagtgggtt ctctctttag cacagggctt tttagcaaat 458040 catgtcatga gtagttactc aagtattttt attttaacac atttatattt tttctatgta 458100 tattcttaaa ttctcttata cttttttctc tgttataaaa acatgctgaa caatctcaag 458160 tcttaaggat tgcagtattg tccccacata ttcatgtatt ttggtactca attctttata 458220 ctttctttga cagatcactt gaactggcac atgtctcttg ttttgcagag agggaattaa 458280 tgtgatacct tcatgctttt ctattctatg tgctacataa ttgaatatac aagcaaatat 458340 agttgttaag atttagtgtg attatttcta caccacatgc aaagaagttt ctcatagatc 458400 ttaatagagg cccacatgca ttgtacagtt tagaatttgg ggaaatattg atgaagttgg 458460 gtaaagtata aagccaaaag tcagaacagt gaactccttg cttaaggatt tccttggaga 458520 ttacttagtc aatacacaac tgataaattt aagtgctttt caccttttga gttctcgaca 458580 tactaaagct aaaatgtgtt tcaactttta atcctgcttc cctgattttc ccttttttag 458640 tctgagatca aagagtttca gccataaatt actgccaaga gtaatcactt cattttaaga 458700 aagcttaaca atatagaaga atataaaatt atttatgaca gatgtatttt taaccttttc 458760 cccatgcttt ccagaggaaa tatgtttaat catctgccct atattaggga aaaactttct 458820 atgctaatac aagtatctat caatccattt atctttctat ataagatgta ttgatcataa 458880 ccaattaact ttactgtaaa tgagctttag atttgacatt ttggtagtaa tatatgttgt 458940 acaatctcct gaggtcctat aggtcttgag gtctctatgt caaaaactat agatgtgcca 459000 gtgtcctcag tgaatgtgaa ggacaccaca ttttccttag ccatttcttg ttttcagaat 459060 aatggttatc aacattttgc tactgcaaga taccatacat ttataatcgg aatatgccag 459120 tttttatgca ctcatgcctc tgtttctgta gagcattccc agaatgagta atgcttgaaa 459180 attaggtcca tgtgatttct ttaatgagtt atagtcaaat catgaaatat tcaggttacc 459240 attatttcag taatgtatta gaatgtcaag gtaaagttat ctacattgta tatatacaca 459300 caacatagat ataatttata caacatctat atttatacaa cagatatata tttatgtata 459360 tatttataca acataaaata tattttatta tttaaacata aaatatattt tattatttaa 459420 tatagattct taagtgataa atatgtttaa tattattaaa ataggttaaa ataggttata 459480 gttagtacag tgaaaattgg cagccctttt acaaaacata tgccataact atagcattta 459540 tcactgacag tcataccagg atagtctttt atttccaatc acttaaatat tcctaattgc 459600 aaaagaaatt tgaagactaa aattcagaag ttttgaaaga gccattgcct gggtaaacta 459660 tacaggtttc agttttattt ataataatta tgaggccagg cgcagtggct cacacctgta 459720 atcccaacac tttgggaggc cgaggcgggt ggatcacgag gtcaggagat cgagaccatc 459780 ctggctaaca cggtgaaacc ccatctctac taaaaataca aaaaattagc cgggcgtggt 459840 ggcgggcgcc tgtagtccca gctactcggg aggctgaggc aggagaatgg cgtgaacctg 459900 gtaggcggag cttgcagtga gccgagatcg cgccactgcc ctccagcctg ggagacagtg 459960 cgagactccg tctcaaaaaa aaaaattatg tatatattta taaattaata cttaataaat 460020 taataacttg tgataggcaa tgcaaagatg acagtaaaag gacaaaattg attagattga 460080 taaagtcctg ttaacatgaa gaaattgacc aggataccat ccacactata aagttagaga 460140 aatttatcag gacaattccc taaaatactc ttctcaattt taacattgta acaggaattt 460200 ttaaaatttt ggtattatgt gtgtttcctt ccagataatt tgaacagatt catatttggt 460260 atttttaaaa gccatatctt tgtccttagt gctggcaatg tattcttgag aatgaacaaa 460320 taagagatac gtaaaagcat aagagaaggt atcaggttga agtagtcaat cagttataca 460380 gaacacaaag aattttatct tgtataatgt ttatatagct ttatagaagt gtgctgaaag 460440 ggctataaaa catggacatt attatctcat tgaaaggtcc aatacgtact gaaatacatg 460500 cttttatttt gaaccaacca ccctataaac gttgtatggc ttatttagat gagagcccag 460560 gttgtgtgtg tctgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtacc 460620 tgacagggaa gcaagaacat cgagttgcca atgcactctg tctatggtta gaatcatgct 460680 gaaaacatgg ctcccccagt tctggaatga gcccacagat caagcattcc ccaaagacat 460740 agcaggctca aatccctgtg tacacaatat tttatgatta tcttatgtca gtactttcaa 460800 agtatacagt ttgtgtgaag acaaatccaa tgtcattttt cttggctagc ctatatgtgt 460860 ggtaaatcca ttatttactt acttgcttcc tgaaaattac aattagatta acaaactgca 460920 gcaaagtggg catgatgaga tagagattga agtgtaagct tatgttaatg atgcccttgg 460980 tttggataaa cacatctaag agaaaaatgg aaaaacacac atggcaggga agccttgata 461040 gagccaaaat ataggattgt atgtagtaat gcaatccata gatgagcatt tggcagtaat 461100 attatttttc agatatggat aaaaattgct taggagagta aagagagaca aagttgaaag 461160 caggtttata gtaggtgttg ttttagtgtt gatccctttt tgctccaata atcaaagtga 461220 taaatattga aaattgattc atgcagcatt acttactcca ttctaatttt tatatatgtc 461280 aaaagtgcca tctcccaaac tgtgctatcc ccttcaggag aagagactct gctgaagttt 461340 ataaggttga catattgcca gcttcaataa tgtaaagatg aagtgtatac tgaattctta 461400 atgcaaataa caactctatt ggaaagtaac ccagttatag aagtgctaat ttgtcaggag 461460 ctgccttacc aagatcatga tgagtacagt tatctcagga ttctgaaaga ttgttttccg 461520 atttcaacta gtctagctga atgttccttg atagaaagag aggactttta gaattggttc 461580 aatatgatga cctcctgaat tatctcacat agcccgtttg tacatgcctt tcttttctct 461640 cagaaaatgg cactatcata atagctttct tacacagact tcaccttagg gttttacatt 461700 aagggagggg tctggtgttt catttatttt gaagtatttg ttgttgattg tgtacagtgc 461760 ttgagtaaaa aattgaatat agaaacatct agaatatttt tttaaaggat cagtgtttat 461820 aaagtgaatt attagtgtca ataatgttgg gaaagtttta agagaatata ggaaacttga 461880 acattacaca actacaatgg gaccaaattg tggggtctca ttatagttaa tatttatgta 461940 tttttttcca attgatttgt gtgctttttt tctgcatgtt tttggcagat agaatggcta 462000 taacaagtaa cagcatgtca ggtaataaaa ataagcagag ccctattcct ttaaaaatct 462060 tcactgatgg gagggccata aaataagtct taatacattt aaagaattaa attcatgtaa 462120 accatgttaa tttaattcca caatgatatt gaattagaaa taagaggaat atctcttgaa 462180 catctcctaa atgtttggaa atttaaatta gcatttctga cctatttatt ggttaaaaaa 462240 gatacaaaga aaggaaaatt gaaaagtctt ttgaactgaa taaaaataaa aatatagaat 462300 ctaaaacttt atgggatact gacaaaacag gatataggga ataatttata gcactgaaat 462360 gcctatatta gaaaagaaaa aaggttttaa atcagtaaat ttgtatttta ccttaagaaa 462420 cttagaaaag aacaaattaa cccagactta agtaaaataa aggcactaat aaagataaga 462480 gcagaaatca atgaaatata aaacaacaaa acacagagaa aaattgagaa aatttaaaaa 462540 tagcctagtg agaagatatt gataaacttg taaccagacc aatttaagaa aaaaagtcaa 462600 aacacaaata ccaatatttg aaaatgtagg agggcaaatc attacagatt ctatgaatac 462660 taaaatgata ataaggaaaa attatttaaa aggggcatgt cagccaggca tggtggctta 462720 cccctgtaat cccagcactt tggcaggccg aggtgggagg attgctagag ctcaggcatt 462780 cgagaccagc ctgggcaaca tgttgaaacc ttgtctacac aaaaagtaca aaaattagct 462840 gggtgtggtg ttgcacactt gtagtcccag tcacttggga ggctgaggcg agaggatcac 462900 ttgagcccag gaggttgagg ctgcagtgag ccatgtttgt accactgccc tccagcctgg 462960 gtgacaaagt aagaccctat gtaaaaaaaa aaaaatgtat gccaacattt ttcaataact 463020 taaatgaaat ggaaaaattc cttgaaagac acgaactaca aaaactcagt gaacaagtaa 463080 ataacctgaa tagccctgta tcaagtaaat tgaatttgta gttaaaagcc ttccaacaga 463140 gaaaacttca ggtacctata gcttcatatg aaatgaaaaa aaaaatacca atcctctaca 463200 agattccaga acatttaaaa gaagggaata tttcccaact tattccattt ggacagcaat 463260 acccaggtaa gaaaaagaga cacagaaatt taaaaagaag aatatacatt attccttagg 463320 aacataaatg caaagaaatc taatcaaaat tttggcaaat gaaatgtaga aatactttat 463380 gaccaagtga gagttaccca aagaatttaa ggttggtttt atatgtaaag atcaaccaat 463440 ataggaaaat cacttctgga aagtcagagt aagaaactcc aaaaatctac tcctccataa 463500 aaccaataac agccttgata gaaatagttg aaattaattt tccaaaactt tggaaattaa 463560 ccaaaggctt acaaaattcc agagaacatt aattcaagaa aaatggctga atcagtaaga 463620 acagccagct ttgtggcatt ttaatatgac cccttcccat gcttttctcc ctagtgctga 463680 gatagtctta aaaattagca ggatagcaac cactggagaa gaaaggtttg gaaatttccc 463740 aaaaagttcc atccccatag aattatcact atttgacctc taaagcccaa tctataggat 463800 ttatattcat ttggactgac tcagagctca ctcagtaagg aaatctcaat ttcaaggtat 463860 tggtcaaaaa gaatccatgg caattgttga ctatcacaac tgcctgaagt cttggtaaca 463920 gttgggataa acaagaagct gatcaaaaac tgaaaactaa aatcttggga atgagatatc 463980 tacaggatgc ttcaaaaagc tttgatacat tcctgtttat ctagaaagct acatgcaggc 464040 tgggtgcagt ggctcacacc tgtaatccca gcactttggg aggccgaggc gtgcggatca 464100 tgaggtcagg agtttgaggc cagcctgacc aacatggtct ctactaaaaa cacaaaaatt 464160 agccaggcgt ggtggcgtgc atctgtaatc ctagctactc aggaggctga gacaggagaa 464220 tcgcttgaac ccgggaggcg gaggttgcag tgagccaaga ttgtgccact gcactccagc 464280 ctgggcgaca gagcaaggct ctgtctcaaa aaaaaaaaaa aaaaaagcca catgcatgta 464340 attgtttacc tctggctttc cttttatgct ctgggcaagc taaggaagag ttgtgaacta 464400 cctaagtgct gaatgggaac cataacacac acacacacac acacacacac acacacagca 464460 ccttagtaaa gggtgagagg catgttagtt agaagcatta aaggaaatct ctttctagtc 464520 attatctgtg cactaaccta actgagcaga gacttcagta tccacatact acagggcata 464580 taaactttac agaattagtc caggaaaatc atatctaaaa aaaaaaaaaa gcagtaacaa 464640 aaataaactc tgggaaaggg gagaatatga tttaaagagt tgccacatta tacataatat 464700 gtctagtgtt caacaaaaaa ttacgagaca tgcaaagaaa tagaaaaata tggcacaaag 464760 aggataagat gaagtcagtg aaactatcct cgaggaagac cagatgttgg tcttactaga 464820 cacagacatt gaaccagcta ttaaaaatac gtacacagaa ctaagaaaaa catgtcaaaa 464880 gggttaaaga aaggtataaa aatagtgtct taccaaatat agactaccaa taaagagata 464940 gaaattataa gaaaagacaa catgaaaaaa tataaagcaa aaaaattaga caattgaaac 465000 aagagggcct ctattcgcag atttgagcag gcagaagaaa gaatcagtga acttgaagat 465060 atgtcaactg agattatcca gtctgagcaa caaaggtggg aaaaaatgaa gaaaactgag 465120 caacaaagaa ctgtagaaca gcatctctca taccaatgga tacataaact ggagccctag 465180 aaggatgaaa aaaggagaag gaaagaaaac ttcccaaatt ttaagaaaaa cattaattta 465240 tatacccgag atgaccaata aaatccaatt aagataatct caaagagacc aacacctata 465300 cacatcatag tcagcgtgtc aaaagacaaa cataaggaga gaattcttga agatagtaag 465360 aaaaaaatta ttcataacat acacaccatc ctcaataagt ctgacaattg acttctcact 465420 gtaaaccatg caggctaaaa aggcaatgta cataaccaaa gtgatgaaat aaaaaccttc 465480 aaccaatcat tctagatcca acaaaactat tgttcaaaaa gaagaaatga agacattcct 465540 aaacaaaatc tcagagaaat gttctctata agacttgtcc taatagaaat gctaaaggaa 465600 ctccttcggt ctgaaataga aaggcactgg agagtaaatc aaatccacga gaagaaataa 465660 agagaaccag tataagtaac tacatgtgta agtttaaaac aaagtataaa tttattttgt 465720 ttgtaacatt tgtcttttcc tatttgattt aaaatataat ctcaattata aacttgtgtt 465780 gatggtatta tataaagatg taattttggg ttatagcacc aaaatggcag aataggaatt 465840 ttctgtaggt gtttcccaca taagtatcaa ttttgacaac catccatggg caagagtacc 465900 ttgtgggagt tcaggagttg acagtaaaac ttcagcacac cagaggagta aagaaatcta 465960 agaatagatt cattggaaag ggtataaaca gtttcacttt acctgcatca ccaaccccca 466020 aaagtggcac agctcagtaa caagagccca ttatttcttc cacagaggaa aaggagagta 466080 taataagtaa gtgtccagtt tctcaagaca tacaggcccc tgcccaagag atccacttta 466140 ttttcatctc acccagaata ttgaggtgat cagcaaggtg gagtggttgg gagagggtaa 466200 aagcaggaaa gagagatggg gactcaaaca gcagcccata cttggaactg ccatagatcc 466260 taccagttac ttcatggact ccatcaggaa cccacctata agccacaggg gatgcatccc 466320 tcccatcttg ccaacaaaac cccgaatgct ccaaatgcct cacccactct ttggctggct 466380 cccaagtgcg ctcctgtgaa aagcgagtga gtatctctgc agatggcttg caagcacatg 466440 ttgacagctg gctccactct gtagaactgg aaaaaagctc acatacatga gaatttcagg 466500 acactaccct aaaaaaaaaa atgagacttc agcacctggc ctggctttat gcaacctaga 466560 gaaggtgata tgatttggct ctgtgtcccc acgtaaatct catgtcaaat tgtaatcccc 466620 acgtgttgga caagggactt ggtgggaggt gattgaatca tgcgggtgga cttccctctt 466680 gctgttcttg tgatagagtt gttatgagat ccagttattt gaaagtatgt agcatgtccc 466740 ccttcactct cttgcactcc tgctccacct tggtaagact tgcttgctac ccctttgcct 466800 tctgccatga ttgtaagttt cctgaggcct cccagctatg cttcctgtat ggcctgcaga 466860 actgaactgt gagccaatta aacctctttt cttcataaat tatccagtct taggtagttc 466920 tttatagcag tgtgagaatg gactaatgca gaaggcatac aacctttaga atttgccccc 466980 ttgagggaac aagatgtgtg aagcaggttc atccatagaa aatgtctgag agaacctcaa 467040 aatccctaac ctgactaact gatgaaagtg tttctctcct aaggccagtc agtaaagacc 467100 agagggggtg actgtttctt taaatgcaaa ggcagcagca caataattca agaaacatga 467160 aaaatcaaga aaacatgaca ccaccagaag aacacaatca ttttccaata accaactccc 467220 caaaaatgga gatttacaaa ttggtttata atgaattcag aacaattatg ttaaggaagc 467280 tcagcaaact aaaaggaaca ccaatagact actctgtgaa gtcaggcaaa caattcatga 467340 acaaaactag aaattcaaaa aagagaaaaa ttatcttaaa agaaaaccca gaagttatgg 467400 agctaaagaa tacaatgcat gaaatgaagg agcgtatcaa cagcaaagtt gatcaagcat 467460 aagaaaaaaa aaatctgtga aactgaagac tggctatttg aaattattca tcagaggatt 467520 aaaaaaaaaa gaatgaaaag aaataaagaa agcctacagg atgtataaaa caccatcaag 467580 agaactaata taaggattat tggagtcata aaggagaaga gagaaaaggg tagaaaactt 467640 atttaagaaa taatggctga aaactctcca aatctaggaa aagatatgag catccaggta 467700 tatgaagctc aaagatcccc gtacaggata cattccaaaa agacttcacc aaaacacatg 467760 ataatcaaac tgtcaaaagc aaaatcaaga cgatgaataa accaccaatc actaagaggg 467820 agacaggatt cttatgttgt cattattatt tacatataat ttcagtaaat gttattggaa 467880 aatttataat gttttaaaaa aagaaatttg aaagcaccga aagaaaagag actcatcaca 467940 tacagggaac ccttttaagg cattcaagag atttctcagt agaaacctta caaaatagga 468000 gagagtggga tgaactatac aagtgctgca aggaaaaaaa tgccaaccaa cgctttacct 468060 ggcaaatctg ttcctcagaa atgaaggaga gagaagaact ttcctagaca aacaaaagct 468120 gaggcagttc atcaccacta gacctgcctt acaagacata ctaaggggag ttcttcaagc 468180 tgaaatgata tggcaatagt tagtaatatg aaatgataaa cctcactggt aaaggaaagt 468240 acatagtcaa atttagaaca ctttgatact ataatgatgg tgtataaata attttactgt 468300 gctatgaagg ttaaaagaca aaagtattaa aaaaaaccca tagctgcaat agcttgtcaa 468360 tgcatactac agtataaaaa gatgtaaatt agaacattaa aaacatagca tgcaagggta 468420 gggaagtaaa agtgtagttt tcatatgtaa tcaaatttaa tttgttatca gcttaaaata 468480 aattgttata cctatgtttt atgtaagtgt catggtaact ataaaggaaa aacctctagt 468540 agatacacaa aagaaaaaga gaaaggaatc aaaacataac actacagaaa attatcaaat 468600 tacaaaggaa gacagcaagg gaggaacaaa gtaaaaagag caagaaaaaa tttaacataa 468660 tgaaaacagt aagtccttac gtgtcaataa ttactttaaa tgtaaatgga ttaaattatc 468720 caaacaaaaa aacagactgg acaaatggat tttagaaaca acaacaacaa caaacaccgc 468780 acacacacac acacacacac aaaccaccca gccccaacta tgtgctgcct acaagagatt 468840 tacttccact ttaaggacac atacaggctg aaattaaaag aacagaaaaa gatattgcat 468900 gcagatagaa accagaagag aggagaggca tctatactta cagcatacag aaaagatttt 468960 aagttaaaaa ctatatcaaa aggctaagaa ggtcaaaatg gtgaagcagt taattgttca 469020 agaagacata aaaattgtaa atatttatac acccaatatt gaagcaccta aatatataag 469080 gcaaatatta atacatataa aaggagaaat atacagcaat acagtaatag tagtgaactt 469140 cagtgcctcc ctttcaaaaa tggataatcc agacataaaa tcaataagga aacatttaac 469200 ttaaacttca ctttagacca aatggatcta acagacatta tactgaacat ttcatccaac 469260 agtggtagaa ttcacattct tctcaagcac acatggaaca ttctccagga tagattatat 469320 gttagctcac aaaataatat tacaaaattt aataaagctg aaatatcaat tattttgcac 469380 cacaatagta taacactaga aatcaataac aagatggaaa ctggaaattt acaaatatat 469440 agcattaaca tattcctgaa caaccaatgg gtcaaagaaa aaaatcaaaa taattttgtg 469500 acagcaaagt agaaacacaa cataccaaaa catacaggac acagcaaaag cagttctatg 469560 aggtaagctt atattgataa acacatttaa aaaaagattt taaataaaca acattacacc 469620 tcaaggaact acaaggaaga aaaaaaaaca agccccatgt tatcaaaggg aaggaactaa 469680 caaagatcag acagaaataa atgaaacata gactagaaaa acaatagaga ctattaataa 469740 aacttagagt tagtttttta aaaaataaaa tcaacaaacc tttagctaga ctaaaaaaag 469800 agaagactca aataaaataa aaaatgaaag aggagacatt acaactgata ccacagacat 469860 acaaattaag agaaaactat atgccaacat attagttaac ttgcaatggg taaatcccta 469920 gaaacataca acctacaaaa actgaatcat gaagaaatgg aagatctgaa cagatcaata 469980 atgaataagg gaattgaatc aatattcaaa aatctcacaa aaagaaaagc tcaggatcag 470040 atggcttcac tggtgaagac tgccaaccat ttaaaaaaat taataccact ctttattaag 470100 ctcttccaaa aaaattgaag aggagaaaac actttcaaat tcattataag aggccagttt 470160 taccttgata tcaaagattt aaaaagaaca ctttgagaaa ggaaaattac aggccaaaac 470220 ccttgataaa tatagatgca aaaatgctca gcaaaatact agcaaaccta attcagcaac 470280 acattataat ggcatacatc atgaccaagt gagattcatg cctcggatgc aggatagttc 470340 aatataatca aatcaacaaa tgttacacta ctttaacaga atgaaggata aaaatcatat 470400 gatcatctcg atggttgaac tagtttacag tcccaccaac agtgtaaaaa tgttcctatt 470460 tctccacatc ctctgcagca cctgttgttt cctaactttt tacagatcac cattctaact 470520 ggtgtgagat ggtatcttat tgtggttttg atttgcattt ctctgatggc cagtgatggt 470580 gagcattttt caagtgtctg ttggctgcat aaatgtcttc ttttgagacg tgtctgttca 470640 tatccttcac ctactttttg atggggttgt ttgttttttt cttgtaaatt tgtttgagtt 470700 ctttgtagat tctggatatt agccctttgt cagatgagta gattgcaaaa attttctccc 470760 attctgtagg ttgtctgttc actctgatgg tagtttcttt tgctgtgcag aagctcttta 470820 gtttaattag accccatttg tcaattttgt cttttgttgc cattgctttt ggtgttttag 470880 acatgaagac agtgtggtga ttcctcaagg atctagaact agaaatacca tttgacccag 470940 ccatcctgtt actgggtata tacccagagg attataaatc acgctgctat aagccataaa 471000 aaatgatgag ttcatgtcct ttgtagggac atggatgaag ctggaaacca tcattctcag 471060 caaactatca caaggacaaa aaaccaaaca ccgcatgttc tcactcatag gtgggaattg 471120 aacaatgaga acacatggac ccaggaaggg gaacatcaca cactggggat ggttgtgggg 471180 tggggggagg ggagagggat agcattagga gatataccta atgctaaatg acgagttaat 471240 gggtgcagca caccaacacg gcacatgtgc acatatgtaa caaacctgca cgttgtgcac 471300 atgtacccta aaacttaaag tataattaaa aaaaataatg ctgctataaa gacacgtgca 471360 cacgtatgtt cattgcggca ctattcacaa tagcaaagac ttggaaccaa cccaaatgtc 471420 catcaatgat agactggatt aagaaaatgt ggcacatata caccatggaa tactatgcag 471480 ccataaaaaa gatgagttca tgtcctttgt agggacatgg atgaagctgg aaaccatcat 471540 tctcagcaaa ctatcacaag gacaaaaaac caaacactgc atgttctcac tcataggtgg 471600 gaattgaaca atgagaacac ttggacacag gaaggggaac atcacacact ggggcctgtc 471660 gtggggtcag ggtaggggga gggatagcat taggagatat acctaatgta aatgacgagt 471720 taatgggtgc agcacaccaa cacagcacat gtgtgcacat gtaccctaga acttaaagta 471780 taataaaaaa taaatcatat catcatctca gtagatttag aaaagcattt aacaatattc 471840 aacatccttt cagaactaaa aactctcaat aaatcaggta tagaaagaat gtgcctcaac 471900 actataaaag ccacatatga caaacctgga ggtaatatac tcaatggtga aaagtaaaaa 471960 gctttgactc taagatcaga accaaaacaa ggatgtccat tctcaccact tatatttaac 472020 atagtagttg aaattctagc tagagcaatt aggcaagaaa aaaggcaccc aagttggaaa 472080 gaatgaagtt aaattgtctc tgtagatgac atgatcttat atatagaaaa cactaaagac 472140 tccaccaaaa tgctgtttta attagagctt aaaaaaataa ttcactaaag ttgcaggata 472200 caaaatcagt atacaaaaat cagttgcatt tctaaacacc aaaaacaagt tatccaaaaa 472260 attaagaaaa caatcctatt tgtgatatca tcaaaaaata aaatactaaa gaataccaaa 472320 gaaactgaaa ataaatggaa ataaatggaa agatagccca tgttcatgga ttagatgaat 472380 taatactgtt aaaatgttca tactacccaa agcaacctac agattaagtg caattcctac 472440 taaaattcca atgacatttt tcacagaaat agaaaacaca ctcctaaagt ttgcatggaa 472500 ccgcaaaaga ctcaaataga tgaagcaatt ttgagcaaga acagtaaagc tggagacatc 472560 acactaccta acttcaaaat tttattaatc aaaacagcat gacataaaaa cagacagaaa 472620 agaccaatgg aacagaatag agagcccaga aataaactca cgtttataga gtcaactaat 472680 attcaacgaa ggtgccaaga gtacacaatg gggaaagtat agtctctaca ataaacagca 472740 ctgggaagac aatatccaaa tgcaaaagaa tgaaattaca cccttatctt ataccataca 472800 cacaaatcaa atcaaaattg ataaagactt aaatataaga cctgaaacca tacaatcttt 472860 aggcaaaaac tcattgacat tggtcttggc aatgattttt ttgatatgac accagaagca 472920 caggcaacaa aagcaaacct aaacaagtgg gaccctaaca aactaaaaag tttctgcaca 472980 gcaaaggaaa caatcaatca tcagaattaa aaggcaattt atgaaatggg agaaaatgtt 473040 tgcaaaccac atatctgata aagggttaat atccaaaaat atataaggaa tgcataaaat 473100 tcaatagaaa taaacaaaca aataatccaa ttttaaaatg ggtgaagaac ctgaatagac 473160 attttttcaa agaagactta cagataggca acaggcatat gaaaaaatgc ttgacatcac 473220 taataatcag ggaaatgcaa atcaaagctc cagtgaaata ccacctccaa ctattaggat 473280 ggctattatc aaaaactcaa aagaaaacaa gctgggggaa tgtagagaaa agggaaaaga 473340 agatccttat acactgttgg tgtgaattta aactggaata gcccttatgg aaaacagcat 473400 ggaggttcct caaaaaatta aaaatagaac tactatatga tccagcaatt tcactattga 473460 gtatatatcc aaatgaatta aaatcactgt cttgaagagg tatttgcaca ctcatattta 473520 tttcagcatt attcacaata gccaagacat ggaatcaacc taagtgttca tcagtagatg 473580 attagataaa gagaacgtgg tatatagaca cagtggaatc tatttagtgt tcaaaaagaa 473640 ggaaatccaa cttttaaaat cctttaaaaa gttaaactca taaaaacaga gaggagaatg 473700 gcggtttcca ggaactggag ggtgggagaa tggggagatg ttggtcaaaa ggtacaaact 473760 ttcagttata aaatgaataa gttctagaga tctagtgtac aacagcatta ctatagttaa 473820 taataatatt ttttatactt gaaatttgct aagagtaaat atcaatattc tcaatacaca 473880 caaaacagaa ctatctgaag gcactgatat gttaattatc ttcattatag taatcatttc 473940 acaatgtata atgaatatca aaacaatagt gtacatctta aatatataca gttttgattt 474000 gttaatcata catcaatgaa gctagaaaaa atgttgtaat ttttaaaaca atagtaatat 474060 aaattagggg tgaaggaatt gacctatgtt ggagaaaagt ttttgtaaac tatttaaatt 474120 aattggtatc cattcaagct agattatttt taattgttaa tttaattgta atactaaggc 474180 aaccactaaa aaagccttta aaaaaatata gcacttgagg ctgggcatgg tggccctcaa 474240 ttatatatat aatatatata aaatatatat tatatatata gtagatgaac aacaatggga 474300 tttaaatggt acactagaaa atatctgttt aacaaaaaga aagcaatagt ggagaaatat 474360 aagaacaaaa ccatgtaaga tttatagaaa atgaatagca aattggttga cctaaaccct 474420 atcttataat tatattaaag ataaatgaaa taaatactac atcaaaaggc agagattatc 474480 agaatagaga agaaaaatcc aaaccataat tcaaccttat gttatctgta tttagaatat 474540 ttagagtcaa gacacaaata gatagagttc catttgggcg tgaaaatatt taccatgcaa 474600 aatgtaatta aaatagagct agagcagcaa tactaatatc tgacaaaata tactttaaca 474660 aaaattgttg ctaaagacaa aaaagaacat tttataataa gacacaacaa ttataaacat 474720 atacaccaaa caatagagcc caaaatatac aaagcaaaaa ctgctagaat tgaagaaaga 474780 tagaaaaatc aatgattaca gttggaggtg tcaataccaa actttcagta atacacagaa 474840 caacaagtca aaagcaaaaa ggaaataaaa aactacacat tatcatacaa caccttaata 474900 cgatatccaa caatagcaga atacacatta ttctgaagtg cacatggaat attcttcagg 474960 atgacacata ttaggctgta aaacatatct taataattta aaagaattga aataatacag 475020 cacatattct ctgactgcaa aatattaaac caattacaga agaaaatgtg ggaaattcac 475080 aatgatatgg agatttaaaa atacttcaaa gtaaccaatg aatcaaagaa caaatcacaa 475140 gagaaattag aaaatatttt agatgaataa aactgaagaa acaacatacc aaaattttgt 475200 ggttgtagct aaagcagtgc ttcaagggaa atgtataaca gtatatccct aaattttaaa 475260 aaaatctcaa tccaataacc taatttttca ccttaagaaa tgagagtgaa agagcagact 475320 taacccaaag taaacagaag gaagaaataa taaagattag catggagata agtagtgaaa 475380 ataaaaacaa tagagaaaat taataaactt gaaagttggt tcttctgata tatcagtaaa 475440 attgacgtat tattagtttg accgagaaag aacaaaagag agaagattca agttactaga 475500 cataaatgaa agtatagata tcaccttaca gaaattaaaa gaattctaac agaatattgt 475560 gaaaaagtga atgtcaaaaa attaaattat atgagataca caaatccctc taaaggcaca 475620 aactaccaca gctggtgtaa aaacatgaat acaccattta cagttaaaaa gactgaatag 475680 ataaaaattt taagaagaaa ttgagtaagt aatttaattt tcaaactata atcccaagac 475740 cagatgtttt cattggtgaa ttctaccaaa ctttaaaagg attaatatct atttttcata 475800 cactctttcc agaaaataga aaaggaggga acactctata actcactgta tgaggtccgt 475860 attaccctta tatcaagacc aaacatcata agaaaagaag actaaagact tatggtttct 475920 gctctgatat gtttggaagt catcactact attgtcacaa ggaaaaatct gaacaaacta 475980 aagtcaacga tttcttaaac taaccataga attgaggtaa cgggcgaaaa ctggagatgt 476040 aggcaaatac aaaaaaaatc acagtttatc aggagcagaa actgctgaaa ccagcaactc 476100 gtatgaacat gttaagtggt aattgacaaa tttctggaga ttgaatgtgg actggattga 476160 gagttaggaa ctcctaagtg cccagttttt gatgacccca cacacttttg taaactagac 476220 ttccaagagc cccagcaagt ttcttacagt gaagactgca gaaaaatccc ctgatgcttc 476280 agataggagg aagggaaaag caactatttt gaaataagcc caggggacaa gtagttattt 476340 ctaaacactc tcagagcatt ttctttcaca cggcaggggg ctccctgcaa gggaagctac 476400 tttgcctgag ccttgtctga tgtaggagaa aaggaattgg atggctcaag ctccatctag 476460 cctttctgat ttatataagg gaagcaaaaa ataggttaag aaactcttct gaaagtcaca 476520 actcagattt attttatatt tatttattta tttatatttt ttgagacgga gtctcgctct 476580 gttgcccagg ctggagtgca gtggcgcgat ctcggctcac tgcaagctcc acctcccggg 476640 ttcacgccat tcttctgcct cagcctcctg agtagctggg actacaggcg cccagctaat 476700 tttttgtatt tttagtagag acggggtttc accacgttag ccaggatggt ctcgatctcc 476760 tgacctcgtg atccacctgc ctctgcctcc caaagtgctg ggattacagg cgtgagccac 476820 cgcacctggc ctcacaactc agatttaacc ataagattat agaacacttc tcctcccaaa 476880 acagagatat agatcaatgg aacagaacag agccctcaga aataacgccg catatctaca 476940 actatctgat ctttgacaaa cccgagaaaa acaagcaatg gggaaaggat tccctattta 477000 ataaatggtg ctgggaaaac tggctagcca tatgtaaaaa gctgaaactg gatcccttcc 477060 ttacacctta cacaaaaatt aattcaagat ggattaaaga cttaaacgtt aggcctaaaa 477120 ccataaaaac cctagaagaa aacctaggca ttaccattca ggacataggc atgggcaagg 477180 acttcatgtc taaaacacca aaagcaatgg caacaaaaga caaaattgac aaacgggatc 477240 tcattaaact aaagagcttc tgcacagcaa aagaaactac catcagagtg aacaggcaac 477300 ctacaaaatt ttcacaacct actcatctga caaagggcta atatccagaa tctacaatga 477360 actcagacaa atttacaaga aaaaaacaaa caacctcatc aaaaagtggg caaaggatat 477420 aagcagacac ttctcaaaag aagacattta tgcagccaac agacacatga aaaaatgctc 477480 atcatcactg gccgtcagag aaatgcaaat caaaaccaca atgagatacc atctcacacc 477540 agttagaatg gcgatcatta aaaagtcagg aaacaacagg tgctggagag gatgtggaga 477600 aataggaaca cttttacact gttggtggga ctgtaaacta gttcaaccat tgtggaagtc 477660 agtgtggcga ttcctcaggg atctagaact agaaatacca tttgacccag ccatcccatt 477720 gctatatata tatatatata cccaaaggac tataaatcat gctgctataa agacatatgc 477780 acaggtatgt ttattgcagc actattcaca atagcaaaga cttggaacca acccaaatgt 477840 ccaacaatga tagactggat taagaaaatg tggcacatat acaccatgga atactatgca 477900 gccataaaaa agatgagttc atgtcttttg tagggacatg gatgaaattg gaaatcatca 477960 ttctcagtaa actatcgcaa ggacaaaaaa ccaaacactg catgttctca ctcatagatg 478020 ggaattgaac aatgagaaca catggacaca ggaaggggaa catcacactc tggggactgt 478080 tgtggggtcg ggggaggggg gagggatagc attaggagat atacctaatg gtaaatgacg 478140 agttaatggg tgtagcacac cagcatggca catgtataca tatgtaacaa acctgcacat 478200 tgtgcacatg taccctaaaa cttaaagtat aataataata aaaaaaggct acctaaaaaa 478260 aaaaaaaaga acacttctcc tcccaacacc atatcaccac atcaaccagg actccagtgt 478320 aatagcagtg aattctaact gaaagaggtg aaagacactg attgtattta agaaagatct 478380 tctaaggaaa tccaaaaata gtaggggaga tcaaaacaaa gatactagag gaaattgaat 478440 atgtgacacc tatagctaca aaaaaattaa acataacata gccctaacca tataaacata 478500 aaacctcaca caaagaccta ttatctgaga ttctgttgcc tgatacattg cgttttattt 478560 caataaaaaa attagagggt atgttaaaaa gcaggaaaag ttagtctaaa gagacaaatt 478620 gagcctcaga agtaggctca gatatggcag agatttggca attataccta gagtttaata 478680 taaatgatta atataataag tgttctaaca gaaaaaggca acatgcaaga acggatgggt 478740 aatgtgatca gcaagaagga aactctaaga aagaagtcaa aaggaaatgc taggaataaa 478800 aacctacaag aaataaagaa tgcctgtgat gggttcctca gtagactgga caaggtcaaa 478860 gaatcagtgg atttgaaaat atgtcaacaa aaactgcccc actgaaatac aaaagaaaaa 478920 tagaatttta aaaacgtaac acaatctcca aaacagtggg acaattacaa aagatgtaat 478980 gtgcctaatg caaatgacag taggagtata aagggagaaa ggaatagaaa atctgaagta 479040 ataatggcag agagttttcc aaaattaatg ctaaaccaca gatacagcaa gcccagagaa 479100 caacaaggag gaaatttagt aaagcgtctg caaccaagta tgtcatattc agactgacaa 479160 aaccaaaggt gaagagaaaa tattgaaaga agacaaagag gaaaataaat atcaagaaaa 479220 tacatacgaa atacatcata catacataag aaatacatca gaccatacaa gcaagaagag 479280 aatggagtga aatgtttaaa atgttgaaaa aaaaactatc aatttgcaat tctgtatcca 479340 gtgagattat ctttcaaaag tgaagaggga aatggcagag aagtcatctc caagacctat 479400 ggtttccctt cacagaaaca ctgaaaaata tgaacaaaag tggtcagaat taactttcta 479460 agaattctat aaaatggtaa aatgtttaca ccagtaaagc aaatgctgaa ttgagaaggc 479520 aacttaaaaa ggtgaagaaa acttcgtatt atttttatgt gtccttgccc cacgtccttc 479580 cctaccttag tcttgaagat ggcagcccac atttctactg tggggctctg gtttctgttt 479640 cctggttcaa gagggagaat aacagacctt acttttagtc attattattt ccttctttct 479700 gatttccttg ggtttatttt gctcttcttt ctactttatt gaaatgagaa ctaagattat 479760 gatttgagac atttttctaa tgtaagcatt tagtgctata aatttccatc tcaacactgc 479820 tttagtcaca tcccacaaat ttttatatgt tgtaatttca ctttcattta gttctatttt 479880 taaatttttt ctttttatac ttcctctgac tcacagatta cttagaattg tgttgttcag 479940 ttttcaagga tattgtagat tttcctgttt ctctgttgtc taatagttct gttccatttt 480000 gtacagatag ctcacgctgt atgatttcaa ttttttaaaa aattgtgctt tgttttatgg 480060 cccagatatg gtctgtgctg tgaatattcc atgttattat aaagtatgcc tgttatatta 480120 ttatatatat ataatatata taattataaa gcatgcccgt tttgtattgt tagcagagta 480180 ttctagaaat gtcaatgaga tcttgttggt tgatggtgct tttcagttct atatctttgc 480240 taattttttt tttttttgct tagtagctat atgagattct gagagaggaa attgaagtct 480300 ccaaccataa ttgtggattt gtctatttct cctatcagtt ctatcagttt gtgcatcaca 480360 tatttgaggc tctgttgttt ggtgcataca caagtggaat cattgtgccc tcttggtggc 480420 ttattttatg attatatagt gcctatcttt gtggtatttt tatttgctct taaatctact 480480 ttgtgttata ttcatatacc cattcttttt taaaaaaaat tgtttgcgtg atacatcttt 480540 tccattcttt taatctcagc ctatctgtgc cattgaattt gaagtgagtt ttcatataga 480600 gaacatatta ttgaatcatc attttaaaaa ttccttttgc caatcttttt tatactgagg 480660 taaaattgac ataaaattta tcattttaaa gtgtacaata cagtggcatt tggtaataca 480720 catgttatgc aacgttaact ctacctggct cctaaatgtt ttcatcatcc ccaaaaggaa 480780 acttcatact cattaagcag ttaattccca ttccttctct cggccactgg catccgcaaa 480840 cctacttttc tgtctctatg aatttaccta ttatggatat tttgtataaa ttgaattata 480900 caataagtga cctttatgtt tggcttcgtt cgcttcgcat actatttttc gatattcaac 480960 catgttgtag tatgtatcag ttttatttga ataactcaat tctttttgtt gtatagctaa 481020 aagttgattc ctaggtcata atgataattc tatgtttagt ttattgaata gctgccaaag 481080 tttttccaca gtggctctgt cattttaaaa tcccactagc aatggatgag agttccaata 481140 tctccacatc cttaccaata ttgttatttt atatttttat aattataatt ttcctagtga 481200 atacgcaatg gtatctcatt gtgtttttgg tttgcctttc cctaatgact aatgatgttg 481260 agcatcttac aatgtacttg ttaactattt gtgttcttta gagaaatgtc tattcaagtg 481320 ccttgtccat tttaaaaatc gagttgtctt gttgacttat gagttcttta atacagtaaa 481380 cgcttatcag atatgattta taagtatttt aacccattct gaaggtcacc ttttcacttt 481440 tgtggtagac cattatgcac aaaggtttta attttgataa atccaattta tccgcttttg 481500 ttgttgtttt tgttgttcgt gcttttgcaa aacctagtgt catgaggttt tctcattatc 481560 tttggagaat tttatagttt gggtctatac atgtagatta ttgatctaat ttccattaat 481620 ttgtgtgtat gctacgaggt aggggtccaa attcaatttt tgcattgaat tgaaaattca 481680 tattttcagt ttcaaatttc aactgcatat tcagttgttg cagcacaatt tgttgaagag 481740 atcattcttt accacaggga atgatctggg acccttgtca aaaatcaatt gatcatagat 481800 gtatgggatt atttcagact ttagatcttg ttccatgaat atgcctattt ttatgccagc 481860 actgcagtat tttcattact gtagctttat cataaatttt gaaatcagga agtatgtatc 481920 ctccaagtgt gattttcatt tgctagagtg ttttgactat ttggggtctt tgcaattcca 481980 tatgaatttc agaattggct tttcatttaa aaaaatggta gttgagattt tcataggaat 482040 tatattgaat ctacagatca ctttgggtag tattgccatc ttaacaatat tgtattccaa 482100 tccataaaca cggatgtatt gccattcata tctttttttc ttttctttcg gcaacattta 482160 gtatatgaca cttgtaactc cttggttaaa tttataccta agcattttat cctttctgat 482220 gctgtttaaa tggaattatt ttattaattt ctcttttaga tggcttgttg caggtgtata 482280 gaaatagaac tgattattgt gcttttattg aattatctga aactttgctg catttattaa 482340 ctctagtagg tttttttttt ctttaaagtt gtctatatat cttgctctgt gaatagataa 482400 ttttacttct tgatctccaa tatggatgcc tttctttctt tttcttacct aattgctgta 482460 gctagaattt tcagtataat gtatgataga agttgttcac aactatcctt gtcttctttc 482520 tgatcctagg ggtatagctt tcagtctttc accattaagc acaatgttag ctgtggggtt 482580 ttcttagatg ccatttaata tattaaggaa gtgctctgct atttctaatt ggttgagtat 482640 ttttattata aaatggtgtt agattttatg actttatgta ctgcataatt gagattatca 482700 tgtggtcttt tcattcgatt aatgtggtat attttatgat tttcatatgt tgatccacct 482760 ttatattctt ggggcaaatc ccactgtgta cacgggtttt ttagggtctc ctaattttct 482820 tcattctttt tcttttctct ccctgagact gaataacgtt aactgaccta tcttcaagtt 482880 tactattttt tcttctgctg ttcaaatctg cttgaaccta tagagtgaat ttttcatttt 482940 acttattgaa cttttcagct ccaaaatttc tctttggcta ctttgtataa tatctatctc 483000 tctatagata ttctctattt ggaaagacat ttttctcctg gttttcttta cttatttgta 483060 ttttttaaag tctttaagca tatttgagac agttgattta agtatttgtg tactaagtcc 483120 attgcctaag cttttgcata gagattttat attaatttct tttttttctg tgaacaggtc 483180 tttttttttt tttttttttt tttttttttt ttagaaaact ggacattttg agtagtataa 483240 acgtggctat tttagaaata attttcctcc ctccttaggt tttgtttcca cttgttgcat 483300 gttgctgttg tttgctcatt agtgactttt ctaaagtatt ttgaaaagtc tgtgttcttg 483360 atcatgtggg tccattgaat tctgtattct gttaatttca tagtcagcta gtgttctgaa 483420 agttccctta agtgcataga gccaataaaa gaaaaagaaa agaaacacag aaaaagaaaa 483480 gaggaaaaaa ggagggaaag agatttaaaa aaataatgtc ggttgggcat ggtggctcat 483540 gcctgtaatc ccagcacttt tgggaggccg aggcaggcaa atcacttaag gttgaccatc 483600 ctggccaaca cggagaaacc ttgtctctac tgaaaatata aaattagccg ggcatggtgg 483660 cacatgcctg taatcccagc tactcgggag gctgagaggt aggagaatca cttgaactcg 483720 ggaggtggag gttgcagtga actgagatca caccactgca ctccagcctg ggcaacaaga 483780 atgaaactcc atctcaaaaa aaaataataa taataatgcc tttgccgatt tgctctgtgt 483840 ttgggccctc attcaatgcc tagtcaggcc atttacaact ctctcttaac tttcactacc 483900 tgcttgtgta ctgactgaag gccacctata ggtgaaagct taacatcatc tcagatcttt 483960 ttggaccatg aatcctaccc tgggtatgca catgatcttc ttaatttccc agtagatgca 484020 agagttttag tgttttaaaa gtccttattc cctcatctat cttcttttct gacctttttc 484080 agtctgctta ttgttcatct gaactgacat cctttgcccc aagcggctgt ggcaaaaact 484140 tttaccttta aatgctttca ccacaagcca cttgggaagc tgccccagac ctgggactgc 484200 tctgaccctg atgaaacaaa gacaagacct tgtacagcca ggcagccata agacaagtcc 484260 atacccaaac cacagttctt tcagaataag gtctatattg gattctctgg ccctagtaac 484320 cagcatgagt ctgggcttgc catcttcatg gccacttgtc ttagtttgct agggctgcca 484380 taacaaaata tgagagactg agtggcttaa acaagagaaa tttatttttt cacaattctg 484440 aagaccagaa gtccattact ctgaaatctc tctccttggc ttgcagatac tgccttcttg 484500 ccgtgtcctc acacagcctt ttctctgtgt acacatccct ggtgtttttt aagcctgtcc 484560 aaattttctg ttcttctgag gacaccaatc agattggatt agcgaccacc catatgatca 484620 ttttacctta agtacctctt caaaggtatc agagtagtat atttgctaca gttgatgaac 484680 ctgcatacaa catcatcact tgaggtctgc agtttacatt agagttcatc gttagtgtta 484740 tatattctag ggtttgtttt gttttgagac agaacagagt cttgctgtgt tacccaggct 484800 ggagcgcagt ggtacaatct cattgctacc tctgcttccc agattcaagc aattctcata 484860 cctcagcctc ctaagtagct ggaactacag gcgcacacca ccatgcccag ctaattttcg 484920 tatttttagt ggagatgggg tttcaccatg ttggccaggc aggtcttgaa ctccttgcct 484980 caagtgatct gcccgcctca gcctccccca gtgttgggat aacaggcatg agtcaccatg 485040 cctggcctta ttctatgggt tttgaaatgt ataatgacat gtatccatcg ttgtagtatt 485100 agatagaata gcttcattac cctaaaagtc ttctttgcac tgggttgagt tttaaaagct 485160 ctttgattat tttatgacag ttccttatta gatatatctt ttgcaagtat ttttatcagt 485220 ctgtggttat cttgtctttt acagagcagt aatttttaat tttaataaaa tccaatttgt 485280 caattactta tctcatatga ctctggtgtt acatctaaaa tgttaccacc atactcaagg 485340 tcacctaggt tttctctagg aattttatgg ttttgcattt tacatttggt gtatgaccca 485400 tttgaagtta atttttgtga ggttgtaagg tctgtgccta gattcatttt tttttttttt 485460 ggcatgttac ttcagtattc ataagaaaca ttgttctgta atcttctttc ttatagtatc 485520 ttagtcttgc tttagttttt gggcaatgct ggcctcactg aataaattca aagtgttccc 485580 tcctcttcaa ttatttggaa aagtttgaga aagactattg ttaactgttt tctaaatttt 485640 tggtggaatt taccagtgaa ccaactggtc ctaggctttt ctccagtagg tggttttgat 485700 tatgctttca atctctttac aagttacaca tctatacaga cttttataat tcagtcttgg 485760 taggttgtgc gtatttagga atctgaccac ttcatctaag ttatccaatt agttggcatg 485820 caattattcg tagttctctg aataatcatt tttatttcca caaaattggt aatatcccag 485880 tttccatttt ttatttcatt gaatcttctt ttttcttagc taatctagct aaatgtttgc 485940 caattttgtt gatcttttgg aagaaccaac ttttgattta ttaattttct ctactctttt 486000 tctgttcttt atattattta tttccacact aatctttact attttcttcc ttctgttggc 486060 ctttaatttt ttttttttaa tttttaaggt gtaaatttag gttgagaaat tttttaaatg 486120 aaagcattta gagctataaa ttttccttct ggtgttcctt tcactacctg ccataaattt 486180 tgatatgttg agtttttgtt tgtcttggag tattttctaa tttgtcttct aatttcttcc 486240 ttgacctatt ggttatttaa atgtatttaa tttttgcata ttgtggattt cccagttttc 486300 cttctgttat tgatttctag ttttattcca ttgtgatcac agaagatatt ttgtataatc 486360 gcagtctatt aacatttatt aagtcttgtg gcctaacaga ggatctatgt tggagaatgt 486420 tccaagtgca attgagaata ctattctggt gctattaggt gaagtattct ctatatgtct 486480 gttaagtcca attcatctat agtgttgacg tttcctgttc cttactgatt ttctgactta 486540 ttattctatc cattattaaa agtggagtgg taaagtctct attattgtag aactctctgt 486600 ttttcaagtc tatcaatatc tgtttcatat attttggagc tctgtttgct gcatatgtgt 486660 ttacaattgt tatatcttct tggcaaattg accagtttca tcaacataaa atataattct 486720 tattgtcttc taacagttta tttttctttt tacataaagc ctattttatc tgatcttaga 486780 ttccctcaca ctccacccca gcacgctttt ggttacattt acataatata tcttttccat 486840 cctttcattt tcaacctgtt tgtgtcttta gatctaaagt gaatgtctta cagacagcat 486900 aagctatgtc attaaaaaaa tccattctgc ttatctctgc cttttgactg gggagtttaa 486960 tccatttgca tttaaagtaa tcactgatca ttaaatactt tcagtatttt gttgttttat 487020 gtatgtctta taactctttt gctcttcatt tccttcaata ttgcctttgt gtttagctta 487080 tctttttgtg tcacactttg atccccttct catttctttt ttatattttc tttgtggtta 487140 ccaggaggac aatgtatcaa cttttaaagt tattacaatt ttattttttt aaatctctcc 487200 cattcgggga ttttaggaag gttaaataat aatgtaaatg agatacctag aacaatataa 487260 gcattcagga attattaact caattccaat ccttcctcca cctccacctc tttctctgtg 487320 agattataga aaagatgaca aaaaggatgt tttctgagcc ctttaattgt tgagaatgat 487380 ctttgagaaa aagaaaaaaa atgaaagcac taggaatgta caacagcctg gaagtataat 487440 taagtgtaaa ttaaatagat aaaagttata agcagaggaa agtatagtag aactcagtat 487500 ttaaaagaga atcaatgtga aaattatata aatttatgta aaataaaact accagacaaa 487560 tctgatatcc ttaggatttt tctttctttc atgtgatttc taattgctac atatgacact 487620 aaaccattga tctgagctgt aagagaaact ggaaattgtt ctgttatctt ttgtaagatt 487680 tctagaacat tttgccctca gacttaaatg ccaacgtatt tctcacttat tgtttactgc 487740 ttttggattt acatatgatt tgattctttc ttatctctta tccttacaat gtaattcaaa 487800 ctgatgccaa tttaagttca attgcgtaca aaaactctac tcctatgcag ctccgcccca 487860 tctaatttac attattgatg tcgcaaattc catctttgta catagtttac atattaacat 487920 ggatttatac atttttatgt atttggtttt taaatcctgt agaaaataaa aagtcaacac 487980 accaatatta aaataatact ggtttttata tttgtccatg tgcttacctt tatcagtgtt 488040 ctttacatct ttatacgggt ttgagttact gtcttgtgtc ctttagttcc aacctaaaga 488100 actcccttta gcatttttat agggcaggtc tagtggtaat gaactctctg agtttttatt 488160 tagggatgtc ttaatttcta gctcctgttt gaagtaaatt tttctggata tacaattctc 488220 tgttgattga tttttgttca ttttcccttc agctctttta aatacattat cccactttct 488280 tctgccttcc aaggtttcta ttaacaaaat tcagcttata atcttattaa agatctcatg 488340 tacatgagtg gcttctctct tgctgttttc aagattctgt gactttggtt tctgatagtt 488400 taaatataat gtgtcttatt gtgggtctct ttggatttat cctagagttt cttggtcttc 488460 ttacgttggt atatccatgt atttcaagac atttgagtag ttttcagcca ttatttcttc 488520 aaacaatctc tcctctttgg ggacttccat tttacctata ttggttcttt tgatggtgtg 488580 gcaccagtcc cctagacttt gttcactttt ttccagtctt ttatttctgc ttctcagact 488640 caacagcttc aagtgttctg tattcaagtc tgctgactct ttcttcttcc agctcaaatc 488700 tgctgttgga tccccccttg taaaattttt aattccattt tagtgttttt caagttaagt 488760 atttttatta ggttcctttt tataatttct ttttgttgat attctcattt tattacacat 488820 aatttgtctg atttccatta gtttttttct ttgttttcct ttagctcttt gaaaatattt 488880 aagacatttt aaaagtcttt atccaagttc aatttctatg gttctgtaga gatattttct 488940 gccagtttat gttcttcttt tccatgggcc atgttttcct gtttctttgt atactttcta 489000 atttttggtt gaaaactgag catttgaaaa tagagccaac tttcccagtt tctgcagaga 489060 gtctttatgc cacagtattc gttcactgat taactgggta tatctaagct tagggagcag 489120 ctgagtcaaa agtttaaggt cttctcaggt cttttctgag tatacatgtt tcctatgcct 489180 gtgtgaaatg ttctcaattt ccctatataa acagctactt cttctttttt tttttttttt 489240 gagatggagt ctcgctctgt cacccaggct ggagtgcagt catctcagct cactgcatcc 489300 tccacctccc aggttcaaac aattctccta tacaggtgtg tgccaccacg tctggccaat 489360 ttttgtattt ttagtagaga cagggtttcg ccgtgttggc caggctggtc tcaatctcct 489420 gacctcagga ggattacagg cttgagccac agtgtccagc ctaaacagct acttttgaat 489480 gctttaattt cctgaatagt ctcaacccag tttttccttg aggtcttagg tggtccattg 489540 tatgtctcca cccatagttg cttgccccag gcatctgtgg gtctgtggta ccactgcagc 489600 tttcaccacc tgtagctgcc acctttccct atctgagatc caggttaggt gagagagatc 489660 attccttcac gcagtcccat gacaggttgg aacatttcaa ataaggtctg ttctgctcct 489720 ctggttgaag ggagaaaatt gggaaccggt ttcccacctt ctacaaacca agatctcatg 489780 ttgccacggg agtggcaggg caagtgcaag tgaaaatgcc atacaatttt ctaccatttt 489840 gaacgcgggt ttttcttcaa tggtcatttg cttggttgct gtaggccttt cactgttttc 489900 cagagctccc ataagattac tttagccagt tttttgttct ttcctgatgc ttccctggca 489960 gagtaagggt tggaacttcc accattttgc tgattcataa ctctgtagtc agttttaaat 490020 atattgatac ttgagtttgt tttatggccc agaatatggt cttggtaaat gtttcacata 490080 tactcagaaa gaatgtgtat tctgatgttg ttacatgggc tgttctataa atgttactta 490140 aggtggttaa taatgttgct caagtcttct atattcttgc tgattttctt ttatttattt 490200 attttatttt ttttattata cttttaagtt ctagggtaca tgtgcacaac atgcaggttt 490260 gttatatatg tatacatgtg ccatgttggt gtgctgcatc cattaactca tcatttacat 490320 taggtatatc tcctaatgct gtccctccct gctcccccca ccccatgaca ggccccagtg 490380 tgtgatgttc ccctttcctg tgtccaagcg ttctcattgt tcaattccca cctatgagtg 490440 agaacttgcg gtgtttgttt ttttgtcctt gtgatagttt gctgagaatg atggtttcca 490500 gcttcatcca tgtccctaca aaggacgtga actcatcctt ttttatgact gcatagtatt 490560 ccatggtgta tatgtgctac attttcttaa tccagtctat cattgatgga catttgggtt 490620 ggttccaagt ctttgctatt gtgaacagtg ctgcaatgaa catacgtgtg catgtgtctt 490680 tatagcagca tgatttataa tcctttgagt atatactcag taatgggatg ggtgggtcaa 490740 atggtatttc tagttctaga tcttgaggaa tcaccacact gtcttccaca atggttgaac 490800 tagtttacag tcccaccaac agtgtaaaag tgttcctatt tcttcacatc ctctccagca 490860 cctgttgttt cctgactttt taatgatcgc cattctaact ggtgtgagat gggatctcat 490920 tgtggttttg atctgcattt ttctgatggc cagtgatgat gagcattttt tcatgtgtct 490980 ttggctgcat aaatgtcttc ttttgagaag tgtctgttca tatcctttgc ccactttttg 491040 atggggttgt tttgttcttg tatatttgtt tgagttcttt gtagattctg gatattagcc 491100 ctttgtcaga tgaggagatt gcaaaaattt tctcccattc tgtaggttgg ctgttcactc 491160 tgatggtagt ttcttttgct gtgcagaagc tctttagttt aatgagaccc catttgtcaa 491220 ttttggcttt tgttgccatt gcttttggtg ttttagacat gaagtcctcg cccatgccta 491280 tgtcctgaat ggtattgcct aggttttctt ctagggtttt ttatggtttt aggtctaaca 491340 tttaagtctt taatccatct tgaattaatt tttgtataag gtgtaaggaa gggatccagt 491400 ttcagctttt tacatatggc tagccagttt tcccagcacc atttattaaa tagggaatcc 491460 tttccccatt tcttgttttt gtcaggtttg tcaaagatca gatggttgta gatgtgtggt 491520 attatttctg agggctctgt tctgttccat tggtttatat ctgttttggt accagtacca 491580 tgctgttttg gttactgtag cctcgtagta tagtttgaag tcaggtagta tgatgcctcc 491640 agatttgtcc ttttggctta ggattgtctt ggcaatacag gctctttttt ggttccatat 491700 gaattttaaa gtagtttttt ccaattctgt gaaggaagtc attggtaact taatggggat 491760 ggcattgaat ctataaatta ccttgggcag tatggccatt ttcacgatac tgattcttcc 491820 tatccatgag cacggaatgt tcttccattt gtttgtgtcc tcttctattt cgttgagcag 491880 tggtttgtat ttctgcttga agaggtcctt cacgtccctt gtaagttgga ttcctaggta 491940 ttttgttctc tttgacgcaa ctgtgaatgg gagttcactc atgatttggc tctctgttag 492000 tctgttactg gtgtataaga atgcttgtga tttttgcaca ttgattttgt atcctgagac 492060 tttgctgaag ttgcttatca gcttaaggag attttgggct gagacgatgg ggttttctaa 492120 atatacaatc atgtcatctg caaacaggga caatttgact tcctcttttc ctaattgaat 492180 accctttatt tctttctcct gcctgattgc cctggccaga acttccaaca ctatgttgaa 492240 taggagcggt gagagagggc attcctgtct tgtgccagtt ttcaaaggga atgcttccag 492300 tttttgccca ttcagtatga cattggctgt gggtttgtca taaatagctc ttattatttt 492360 gagatatgtc ccatcaatac ctaatttatt gagagttttt agcatgaagg gctgctgaat 492420 tttgtcgaag gccttttctg catctattga gataaacata tggtttttgt ctttggttct 492480 gtttatatga tggattatgt ttattgattt gtgtatgttg aaccagcctt gcaacccagg 492540 gatgaagccc acttgatcat ggtggataag ctttttgatg tgctgctgga ttcagtttgc 492600 cagtatttta ctgaggattt ttgcatcaat gttcatcagg gaaattggtc taaaattctc 492660 tttttttgtt gtgtctctgc caggctttgg tatcaggatg atgctggcct cataaaatga 492720 gttagggagg attctctctt tttcctattt actgtacatt tattccacca gtgactaaaa 492780 caggtgtatc aataaaatct gttccctcag gttttgcttc aggtattttg agggtctgtt 492840 atcaggtgca taaacaagat tgttatgtcc tattcttaaa ttaatctcct tataattatg 492900 aagttaattt tttttttctt gagatgcagt tttgctctgt cgcccaggct ggagtgcagt 492960 ggcacaatct cggctcagtg caacctctgc ctcctgggtt caagcatttc tttgcctcag 493020 cctcccgagt agctggggtt acaggtacct gccaccacgc ccggctaatt tttttgtatt 493080 tttagtagag atggggtttc accatcttgg ccaagctggt cttgaactcc tgaactcttg 493140 atccacccac cttggcctcc caaggtgctg ggattacagg tgtgagccac tgcgcctgga 493200 cctggcccga agtaaacttc tttacccttg ctaatgatct ttgctctgaa gcatgctttg 493260 ctggtattaa tatagtcatt ccttctttct ttgattcatg tttgcagggt atatctgttt 493320 ccattctttt acttttaacc tattgtcttt atatttaaag tgcatttctt gtaagtataa 493380 ttggtttctt aaaatccaat tatctgcctt ttaaatgtca tttttatatg atttgcataa 493440 atatgattat tattacagct aaattgaaat ctgtcatctt gctatttggt ttctatttat 493500 cccatttttt tcccctcttt ttttgctttc cttgagattg aacattgtat tagttttcta 493560 gggttgctgt aagaaagtga cataaagtgg atggcttaaa acaacagaaa tttattgttt 493620 cagtttggag gctagtcatc tgaaaccaag gtgtcatcag ggccgtattc tctctgaaac 493680 ctgtagggaa gaattctttc ctgcctgttc tagcttctag cattttccag caattcttgg 493740 cattcctttg cttgtagatg tatccctcca atctctgcct ctatcataac atagccatct 493800 tctcccttta tctgtctatt cttctcatct tataagaaca ttaattactg aattggggcc 493860 cagcatagat taggcctaat ctcatcttga ataggttaca tctgccaaag attcttcttc 493920 caaataagat cacttttaca gcttttacag gtactgagag ttagaacctc aatatatcct 493980 ttggtgggga ccgacctctt acccataaaa agtattttat atgattccat tttatctcct 494040 ttttaggtta ttaactacaa tttttttttc ttttttttga gatggagttt tgctcttgta 494100 gcccaggctg gagcgcgatt ttggctcact gaaacctctg cctcccgggt tcaagtgatt 494160 gtcctgcctc agcctcctga gtagctggga ttacaggcat gtgccaccgt gcctggccaa 494220 tttttgtatt tttagtagaa acagggtttc accatgttgg ctagggtggg tctcaaattc 494280 ctgaccttag gtgatccacc cacctcggcc tcccaaagtg ctgggattac aggcgagagc 494340 caccacgcct ggctttataa ttttttttta attcagtgga tgttttaggg tttatagtat 494400 acatctttat cacagtctag ctccaagtga tatatccctt tatgtatagt acatgaccct 494460 tacagtagtg catttccatt tttcctctct ggcatttagg ctattgcaca cacatacact 494520 caattcatcc ctttgtgtag atccgtattt ccagctgcta tcttttgctt ctgtctgaaa 494580 tatatgtatg atttctttta tgactatttt gagaaatttg gttatgtgca tttgtctatt 494640 tttcttatgt acttttagct catcaatctt aagtctgtga gtttatagtt tttaaaaaca 494700 aatttgaaat tatttggcta ttatttcctc aaatattttt ttctgccgcc cctgctttcc 494760 ctttccttag ggatctctga tttccaccta tattactctg attgaagttg ttccacgtct 494820 cttttgaaaa tctctgaaaa atcttttatc atttggataa tctgtatttg tacatcttca 494880 agtacattaa tattttcttt tgcaatgttt aatctgctgt taatcccatg tagtggattc 494940 ttcatctcag gtattgctgt tttaatctct agaaattcca ttgaagtctt acttgatgaa 495000 aaaggcagat aaaaacaaat gttggcaaag atatggagaa atcagaatct gcacacactg 495060 atgatgggaa tgtaaaatgg tcaaggcaat ttggaaagca gtctggcagt ttctcaaaag 495120 gctaaacgta gttcccatat gacagcaatc attcatctag gtatatactc cagagaaata 495180 aaaacatatc cacaccagaa cttgaacatt aattttcata gcaacattat tcctaggggt 495240 ttaaaatttt ttacattatt tttatttaaa atagagacag ggtctcacta cgttgcatag 495300 gctggtctgg aactcctgga attaagcatt cctcctgcct ttgtcctgtt ttctccactg 495360 gaaaagaata aaactttgta cacttggact aacaactccc gattccctcc tttaccaaca 495420 tgccccacag cctctagtaa cttactctct actttcatga attcaacttt tttaagattc 495480 cacatataag tgagatcata caatatttgt ctttctgtgc ctggcttatt tctcttagca 495540 taatgtcctc cagattcata catgttgtct taaatgacag gatttacctt cctttaaagg 495600 ctgactagta cttcattgtg tatatgtatc acattttctt tatccactta tctgttgatg 495660 ggcacttaaa ttgtttcaat gtcttggcta ctgtaagtaa tgcttcaata aacatgggaa 495720 tgaagatatc ccttcaacat attgatttct gttcttttgg ataatactca gaagtgagat 495780 tactggatca tatggttgtt ctattttttt cagaaacctc catactgttt ttcatagcgg 495840 ctgtactaat ttacattccc actaacaatg catgagttca cttttctgga catcctcccc 495900 aacacttgtt atctttcatc tttttcataa aagccattat ataataggtg tgaagtgaca 495960 tctcactgtg gttttgattt gcattactct aataattagt gtgagcattt tttttttttc 496020 atgtaccgaa tgtcttttga gaaaggtctc ttcattcctt tgcccatttt aaaatcaggt 496080 ggttttcttg ctcttgagtt gtttgagttc cttatgtatt ttagatattt acccatttcc 496140 agatatatca tttatatttt ttcctattct ttgagttccc tcttcactgt gttgtttcca 496200 ttgctgtgca ggtcttttat tttgatgcca ccccatttgt ctatttttgc catgcttttg 496260 cagtcatatc caaaaaaatc attcccaaga ccaatgctgt ggagatttcc ccctatgttt 496320 tcttcagtag gtgtacagtt ttaggtctta tatgttaagt tttaaatcta tttttttata 496380 tggtgtaaat aagggtctaa tttaattctt ttgcatgtgg atatccagtt ttcccaacac 496440 catttattga agaccctgtc cttttatact tttcagtatg cagatctttt acctccttaa 496500 atttacacct cagtatttaa tatttgttgc tattatgaga ttttcataat ttccttttca 496560 gatagctcat taatagtaga tggaaacact actgatttct gtaagatgat tttgtattac 496620 ggaactttac tgagtttgtg tatcagttct accaggtttt agttttgttc tggtggagac 496680 attacagttt tttgtatatg gttatgtcat cagtaattac agatgattta acctattcct 496740 ttcctattag gatgcctttt ttttctttct cttgtccaac tgctctggtt aggacttcta 496800 gtactatgtc aaaaagtgat gagggtcgta catggcctcc atacctaatc tgttgagagt 496860 ttttaccatg aaaccaggtt gaattttgtc aaatgctttt tctgcatcca ttgagatgat 496920 catatgattt gatttacacc ctccattttg ttatgtggta tatcacactt tttgatgtgc 496980 atatgttgaa ccacccttgc atcctaagga taaatcccac ttcatcatgg tgaatcattc 497040 tttgtattcg tgaatccagt ttgctaatat attgttgagg atttttgcat ccatgttcat 497100 cagggatatt actttgtaag tttctgtcct taaagtgtct ttctctggct ttaataacag 497160 tgtaacacta cccttgtaaa atgaatttag aagtattccc tctgcttcat tgttttggaa 497220 aagtttgaga atttttatta gttctttaaa tgtctggtaa aattcagtag tgaagctgcc 497280 taatcctggg ctttcctttg gtgggatact ttttattact ggctcaatct cttttcttgt 497340 tattggctta ttcagatttg tttcttcatg attcactctt tgtaggttgt atatgtctag 497400 gaatttattc atttctttag gtcatccaat ttgatggtgc ataacttcat agtagtttct 497460 tataatcctt tgtattttgg tgatatcagt agtaaatgtc tcctctttca tttctgatct 497520 tatttgagta ctcttttttt ctcctagtct aggtaagaat ttgttgattt tatctttcaa 497580 aaaaaaaaaa aaccaactct tagcaactct tagttttgtt catttttttc cagtctttat 497640 ttcaactgtg atctttgtta cttacttctt tatgctaact ttcgggctta gtctgttctt 497700 ttcctagttc ctttaggtga aaagtgagat tgtgatcctt cttctttatt ggcgtaggtt 497760 tgtatcgcta taaatttcca ttaggactga ttttgctgca tcacataagt tttgtttcca 497820 ttttcatttg tctcaaggta attttttatt tactttttga cttcttctgt gaactattag 497880 ttgtttggga gcatattgtt taatttccac atattgctgt attttccacc agaattgatt 497940 cttgttcttg atttctagtt tcacgccatt gtaatcagaa aagggatttg atatgatttc 498000 tgtccactta aacttaagat tagttttgtg gactaacata tatcctggag aatgttccat 498060 gggcatttga gaacaaaatg tattttgctg cttctggatg gaatgtttca tatatgcctg 498120 ttaagtccgt ttggtctaaa gtgtaattga aatccattgt ttctttattg attttctgtc 498180 taggtgatca atctgcccat ggtgaaaagt agagtattga ggtcccgtat tatagtattg 498240 cagcctatct ccctcttcac atcatttaaa aattgcttta tgtatttagg tgggtcaatg 498300 ttgggtgcat atacttttac aattgttatg tcttcttggt gaattaatcc ctttatcatt 498360 atataacaaa cttctttctt tttatagtat tgacttaaag tctattttgt ctgatagaag 498420 tatagctacc cctgctctca atttccattt atatagaata tctttttcca tcccttcact 498480 ttcagtctat gtgtatgttt agtagaaaag tgaatctctt gccgggcgca gtggctcact 498540 cctgtaatcc cagcactttg ggaggccaag gcggcgggat caccagaggt tgggagttag 498600 agaccagcct gaccaacatg gagaaaacct gtctctatta aaaatacaaa attagccagg 498660 cgtggttgtg ggcccttgta atcccagcta ctcgagaggc tgaggcagga gaattgctta 498720 aacccgggag gtggaggttg cggtgagctg agatcatgcc attgcactcc agccttgaca 498780 atagcaaaac tccgtctcaa aaaaagaaaa agaaaaagaa aaaaaagtga gtctcttata 498840 ggcagtatgt ggttgtgact taaaaaaaaa aaaaaatcca ttctgtcatt ctatgtcttt 498900 ttgttggaga atctaatccg tttacattca aggtaactat tggtaagaaa ctgctagtgt 498960 cattttgtaa tttgttttct gattgttttg taggtccctt gtttcttttt tccctattgc 499020 taccttcctt tgtggtttgg tggttttctg tggtggtgtg ctttgaatcc tttcttttat 499080 agtatatgcg attaccattg tatttgctgt aaggctaact taaaacattt tatccttagg 499140 ctactttaag cgataaaaac ttgcctttag ttgcatacaa aaactctacg ctttcacaac 499200 ccccccgcct ttcgtgattt tgatgtcaaa gtttacactt ttttaaattt gtatctctta 499260 ttgtagctac agttacaatt acttcttgta gctacaactt attgtagcta cagttgtttt 499320 taatagtttc atcttttaaa cctcctaata ggaataacat tgctttacct gccaccttta 499380 caatactaga gaattctgac tatgaattac ttataccatt tagtttttta cttttatgtt 499440 tctcattaac tagcagtctt ttatttaagc ctaaagaact cccttttagt aattccagta 499500 gagcaggcct agtagtgaca aactccctta ggcattgttt atctggaaaa gtgtttattt 499560 ctccctttgc caagtaaagt attcttaatt aacagctttg tttccttcag cactttgaat 499620 ataccatccc actctctact ggcctgtaag gcttttgctg ataaagccac tgaatctgta 499680 ttggggctac cttgaatgtg atgtttctta tctttgctgc tttcagtatt ctttgtcttt 499740 gatttttgat aacttggttg tgatgtgtct tggtgaactc tttaggttga atctgatcgg 499800 tgacctcagc ttcctgttcc tgaattttgt catcttttct cagatttggg aatttttcag 499860 ctattacttc cttaaatatg ctttctaggc ctttttcttt cttttctcct taaggacctc 499920 ctattatgca aaagttagct agcttgatgt gtcctgtaat tcttataggc attctttttt 499980 gtttttgttt ctcattggat aatttcaaat gtcttacctt tgagctcatt gattcttctg 500040 cttgatcaag tctgctgttg aagcgttcta cttagatttt cagttcagtt actgtattct 500100 ttatctttag aatttctatt gtttttgttt atatttgtta aacttctcat tctgttcaga 500160 tgttgttttc caaatttcat ttttctatcc atattttctt gtactttgtt gaacttaaga 500220 ggattagtct aaattatttg tcatttcaca ggtctccatt tcttctgagt ctgttactgg 500280 agctttcata tccaatgtac accagaaact ttgctaattc cacagtaaat gttagaaatg 500340 ggtttttatt gataaaatca gtggcttgct aattagtatg ttagaagctg gcttgcattg 500400 gtgaagttga gggtattcga tatacgtatc ccggctaaaa tacttctaaa gaacctctcc 500460 agctttgcaa gaatagagta taggaatctg aggaggcctt taacatggcc ctcagaaagg 500520 acacacaggg cttgacctct aaacatataa acatatacag aaacgaggtc agaacatgtt 500580 ttgactgatg ccagtagtaa cacagcagag cctattgctg gtcactgtta ccaatacctt 500640 gtgtaataaa cctttcattt aaattgagag gttgtaagcc ccgaaaaagc aaagggctta 500700 cagtacctct tgcctgaaca ctcctgtgtg tgctttctaa gaaatgcttt taaaataatg 500760 cctgtggcac aaattgattt gacactggct ctctttataa gctgctatca aggttgtggg 500820 gaatagctaa ctcttaccca ctttccctga caaataggaa cccgtagtta cctaccaaaa 500880 gtatgtaaaa gctatatccg acccaaaggc cagttaggtc aaaacacctt gaaaggagct 500940 cagtttaagg aaatcagtgg tgtcacagtg ccccactagc gtgtaaaagt tttcatagtt 501000 tgactatcgg atgtgcttag tttcacagct gagtcttacc ttgtgatact tttagagcaa 501060 aagtcaaatc aaagatgatt taaaaaaaca tttcaaagat tcataaagaa taaatgcctc 501120 ctcaggaagt cttctggagt tctgcccact tcccttaggt ggctctttac tgtgcccatc 501180 tcatagcctg tctccttcca cttggtgtat tgcagagtaa agctcactgt ttacaggggt 501240 ggtagaaagt gtggtccttt cccagactcc tttttccctt cctcttctca tttttcagaa 501300 gatgtgtttg ataataaacg aaacaaaatg actaacacat tgagctgagc tacataagca 501360 gatgtcagtt tgacgtgaag agtttaaaag atctatgcat tatctgggga ctcctccccc 501420 agacctgaag gatcaggtgc tgccttctat gccacctgtg cagacagcaa aagaggaaaa 501480 ccatacccac gttcagtatg aacaaagggg acatttgaac tctgtgtgga cccctcattg 501540 gaagggtgtt tcttctcctg ctgcatccac aaagagcact ccttagcctt gccttttgtc 501600 agttctctct ccaataaggc ttgagcagag acaacccagt gcagttcaga gagactgaag 501660 tctggtgttc caggtctgag tcctagctct agctctctgt gtaactttgg gatgtcccaa 501720 agtaactttt cacaacttga taggtgttaa cttgaatttt ggatacaggt gactcttagc 501780 ccatcccctc tctgtgcttc agatatgtca tcacttgggc catatgacct ctggacacct 501840 ttcctacttt ccacaatttc agagcagcag agcagactgg agctcctgct gcctctgagc 501900 ttcagtgaat tatcactcgt tggagggaag cttcaagcat tttgttatct ttcaagagca 501960 aacacagtgt ctgtcagcaa gaatatgtag cagatgctag tgaacagcag tgattagggt 502020 tgaatgctgg atttaaatat ggagcttagg ctgtgaagga agcctgaaga acctagagcc 502080 ccatgaagct gccctctgtg agatctgaca ccatttccca ctgatgagcc atgggtctaa 502140 tgggtagcac tgattccaca tacagtatgt gagtgcaata cagtgaaagc aaagagaata 502200 aaatgatggc taacatgatg ttccaaactt taaacaggag aaaaacacac aattccatta 502260 tgtataagaa cccacacaga gatcaggaga ataacctcat tggagaatga atgacctgtg 502320 tggggaattt agggtagagt tgagattgaa aaaatgggcc gaagtcaggt ggccaagggc 502380 cttaatacct tgtatacaag atgtgtagtc aaggaagacc atgccttact tatgcatcaa 502440 ttcccttggg cctacaaaga gctgcctagc ctgggactgt tgtagagaaa agctacagtg 502500 ttccaatgac acagggactc ctccatgtat gtatgagtgc ccagctggct ctgtaataaa 502560 tcttattttt atttattaac ttttcttgcg cattggcttg atgcatcagt tggaagtcag 502620 aggccaaacg aagtgaacac tgagccaaag gaagttctca gcctttaggg aggcagaatt 502680 cactttaaac acaataaaca aatgaactca cattatacag gagagagtca gaagatccca 502740 gtggctggtg tcatcgggcc atatttgccc gaagtgccta ttccttatag gaacccactc 502800 ccagggttga tgggctacat ccttaggagg ctttatgcct atgttctcct gaccactggc 502860 tcctccaggg ctggcctttt ttagtctctc tgtagaggtt cctgtagctg gttggatata 502920 ggctttcaca gaagggtcag tgccttgggt ctggttacag gactgttaat cttgctttgt 502980 taagagtaat gttatttccc catttccaaa ttctccaggg agatggaatg tcaaagatag 503040 tatgactgta gcacctaaat cctgggttcc agaagcagag aagagaatac actgaagctg 503100 tagaaaggcc tattagtcca tgtcagagat taactggatg cgaggaccat ttctgggatg 503160 gtgtatacag aactggagaa ctggataggg agtcagaaac aaagagctga agatgatgcc 503220 tttgaagttt ccaacgtgga taactaggtc aacagaatat tactcaagaa agtattaaca 503280 taggattgag atgcagtcag tagtaatgga attgaaattt caaagtatat acctcatgga 503340 tctcaggggg tgttgagctg atcacctggg ctaacactcc tatgaccctg gggaaaatca 503400 aatgacctgg tactgtagcc atggtagggg tgtcatcacc ttaatccaac tgggacagtg 503460 ctgtttgata ttcatctgga acttggtgca gacccacatt ttgctgggtt tcaccacaac 503520 caaggctttt ttgattcttt tctcttttaa catcagtaca tcactgcaaa gttaatcctc 503580 atataatagg agatgaaact aattgcttat aaaaacaaga tttttacaac actaaaattg 503640 ttcaagcata tgggcatatt tatagttgca ggcagtgttt cagatgcaga ctgttcttgg 503700 ctgcagtggt tgtttacagg cagcatctgt tctgattaaa tatttgatga ttatccccga 503760 atgttttaaa gcatagtact gggctctgct gactgtacaa caaactggca tttttgacct 503820 atagggcact gggctaggag atacagttct gagggaagtg aaagatagtt aacaactgca 503880 caactgaccc tttattagtt gcaataaagc aatccaacca cccaacccac tgtgatggct 503940 ttcctactat ttaaggttgg tggtgtcaaa gagacaccct cctgtacagt gtgcagtgaa 504000 tcaacatcat ttccacaaaa cctccttcct gcacaaagga attatcatac tttgttacga 504060 agtaaaattt tcctgtatca gtcacaggag ttcaccagtt aagatactgt tagttgaaga 504120 cttctggggt gacttaatga aatagctcag ccatctggtt taaaaactgg attcttctat 504180 ccctccacac agctgtccat gcacctgcat catctcaagg ctggtctccc tggtggtaga 504240 aaggctgaca gtaaaaactg gagccacatg attccttgct taggcagtgt ttcttcatac 504300 tctcacatga gagcaggcat gttctttccc taggctcaca gtaaacactc tgtcaaatct 504360 cacaggccca aagtgctttt ggttatcccc attccaagcc aatctgtggc atggaagata 504420 gcattaccct gactgcctta gactaatata cctactccac ttctggggct gggaataatt 504480 ttgaggtcaa ccatccaaac tgcatgacag ccattccatg gaagaggtat ggcctaaatc 504540 tttggggcaa cctgaattca tgaaaactct cttagattta tgtaactatt tttagaattc 504600 acttctgtat catttaattt tactaataaa aataccacct ttaccctaaa tgtcagccaa 504660 gcgtaaggct ccgttgggac agaaggaact atcaaagctt tgtgttttta tacattagca 504720 gcatttgaca aagaaataac tctgaaggaa ggagaataac caggcagagt ctagatgcat 504780 ggaaaagaag tctttgagaa ggcttcgcag gctgaaggaa agggcaggac tacttcagga 504840 atacaacgtt taagtaaaag aggttggggt ctgttgatct tgaggagaga tgaggatgga 504900 ctggaaaata ggagtgagat atagtaggag aggaaaggat atggatgatg tatatactgt 504960 atgggtaacc atcagtcgac cctaagaaga taatagttgt taaatggtta gctatttaat 505020 gaaagaaacc tgaacaagta ataatcttga gttgcaaagt ggctggagtc acacaacaga 505080 ctaaatttct ggtagaacaa atccagcagc ttatgtgaag gttaccatgt ctgaagctgg 505140 atagaaaagg tctaacttcc aaccaaagtc acagttcttg agctcggtac acagagacag 505200 actgctaaca gctgatgtgt cctcagcgag agtgtcctca tttatatcct cgttctcttc 505260 tgcctccttt ttttgtttta aacttttggg aagtctcatc attcaataca gttctaatat 505320 atcacaataa cagaggcggc ccaatttcta caaattgact aattctatcc ctgaaaagtt 505380 catacaataa aactatacaa agcatcattt tcaaccatcc tatagaaaaa tttccctatt 505440 aaattttaac tctaaatcct ctatctctgt taataacctt actaaaaact tccccatcac 505500 tgcctgccag ggagatcaaa agaaaccaaa tttaagaaac ctccaacacc tgtacctgac 505560 tgaaaagcaa acatacagac ctttcagtcc tgcccctact attcagctcc tatcacagag 505620 acatggtgga tgtccccttg ggaagcggat agctcttagg tggaagctag gcctgcaata 505680 agcaggccag gaaacatgtc tcccaggccc catactcttg gcagaagcac ttggccacca 505740 gacagcatgt cctgtcaacc tacagagttc ttaaaaacaa acactgggac ccagaatagt 505800 accctgtggt catagtgccc acagttcact aagcaccctc acaggtcttt gacagaacac 505860 tgactgccag gtcacctggt gggcagagaa atggaagatt cccaggccca actagcatct 505920 cagggaagaa ccacaagcag agcaactttc agagctggtc ggccagcgtt ggcacccagg 505980 gaagcaagtg ctattccata tttggagaga acataaaact caaggaaaca gagaagtcct 506040 actcaatacc gttctcaact gaaaacaaga gaacttgcaa aaaagaaacc cagttttctg 506100 gagtccatgg agaaatatga agccaatgct cggctaacag agcagaaagc cttttataaa 506160 taatgccagt caaagctcca aaggtcagag ctgatgcatg ccggattgtt ctgacaattt 506220 cttaggtttc taggcaacaa ggagctggtc aaacagctca cctccaagga catactttat 506280 aataccaccc tggtagacga gagcgaggca gcagtgaagg caatagtcaa gaacaggaga 506340 gggaggtaaa gaacaagatg ctcttcagac agtctggaca aagacagtcc ctacccagct 506400 ctcaggagtt gcctccttaa gaaggtggag gcccaggcag ctcccagggt gaccctaaag 506460 acagactcca aggaaaaggg tgtgagggca atggtgaata taaggaggtc ccctttcagt 506520 aggcagagca agtcagttca ggtcttattt ttagagtctc tgaacagtga agagaagctt 506580 tctgtggaca gcattccacc accatgggag gggaaaggtg ccatgagaga cttctccagt 506640 ggggcataca agcattgtgc agtgatcccc aagatccagc cactggcagg aaatcgaaag 506700 gcaagcttct taaatacata gtatatggag acagaagtgt ggagcactcc caaaatgaaa 506760 ggccaagacc caggaacaac ctccacaacc tggagtatat acaaatgaac ccagccctgc 506820 tgactcagat ccacaccatc ctaaagcagg ggtttctcat gaatgaaagg gctaagtatt 506880 tggtggagag aatgagaagt ctcccactgc ccacacattt tttcttcaga gatttctttt 506940 ccaagagccc cttgaataaa ggaagggagg gagcactgaa tgccccagaa atcagaatgc 507000 atggtgcggg aagacgacag gaaatagttc tcaaagagat cagaaaataa attggaagca 507060 atttcattac cacaaagaac agacattttt tctaaggcac ccctcccctt tccacccaat 507120 tgtcattcag caactactga atacttacca atgaaaaacg ttacccctga cctcaaggct 507180 gctcctgagc tctggtagaa aatgctttcc ttgtctataa aacatggcaa gcaaggcagg 507240 atttaacagt aagggcacag tagcactgca agccttcaaa tggaaacctg gagacaagca 507300 gtgagaacag gaagcaaaag cagggcaggt gaagctagga ccagggcatc tggaactttc 507360 cacacaggtt ggatctccat gccagacaac agttttcaag gaaaaatatc taagaggaac 507420 atgactttgg gaaacttttt ggcagtactg cttactgtat actagagagt aaaagaattt 507480 ggggaacatt caccaatttg cttcttcagg ggcttgggta gggaacgtga acaggaacct 507540 ggctctaatt tctgaacttt tttatcagta aaaacaatcc aacaaacgaa agctagtcag 507600 tgagagaact gggagggtct gccctccttc cctgagtcaa gccttctggg gggacctcct 507660 gacatttaat taagcaaaga caacgcccac tgaaggaagc tgacctgaaa gtgacacgct 507720 actgtgaaat gagcatgaag tgggagcttg ttacatatat gaaatggcca gcgatcctga 507780 gcaaagcgct tcagagcttg agacctaagt cttctcatct atatactgag ggctggacaa 507840 gatgatctgt caagccattt ttatccctaa tccaccaaaa tccaatgctt tagtttattg 507900 tcacaaaagc aggtatcgaa tggctatcct gcagtgcctc caatcaacat tcagactttt 507960 tccctgaggc aatataagat aacagttaac atgtttttat caattaggtg gtcatgagat 508020 aaatatatat gggaagtggt agtttttcac ttaaatgcat ataataatgg tacagctctc 508080 tttgaatagt atttgtttat ttcttaaata tttaagttcc taaagacggt aagaataacc 508140 caaggaagtg aaatcaatgt cacaaagcac atggctaaat aactgcaggt ttgcagtgcc 508200 atgtgtgaga tcagatgaca gaagggagaa ctacctttag gcagaggctt ctcatgtccc 508260 ctggagtggc catgtgctgt tctacatgac tacttccact tcggttatgt agaagctatt 508320 taaagcacac agatgtttgt gatgagaaaa aagccaccct taattgaata atggaaatta 508380 taagcatgat ttgagggtgg gggtggaggt gggagtagag atgggtagaa aggagtgcaa 508440 tggaaacaaa ggagccttca taaaattcaa gtcacttctt aggataacgt gattgattta 508500 ctcaccacct tcttaggaac ataaagcaaa caagtgggtt ttccttttac tgcttttctg 508560 aaatgagcta cactcaagaa agcagcacgg gggttgtgct gtccctgcac agtggcagga 508620 gagtatgagg agcaggtgaa tgccacaaca gctccatcca agatcatttt tcacatgcag 508680 gaaccattct tatactaccc tttactggta atttctgtag aaatctggaa gtctggttga 508740 caccctcctg tacagtgtgc agtgaatcaa catcatttcc cttggacttt gcaatcacgg 508800 tggcattcat acattcattc aacaagtatg tatgtacagg acagtggagt aaagaaaaca 508860 gatagttctt actctcacga ggcttaaaat ttcaggaggg aactaggcag tcatgaagta 508920 aacataaaaa cacagattgt aataggcact agagaataat gaagactttg gggaacacaa 508980 tttaaattgg aaaaatatct cagttccgtt aacacatgtt gaaggggaat agcattgttt 509040 tgctggattt ggggcctgga tgcaagcatg ttgggtatgc attgtagggt aatgcatttc 509100 cttccatttg ggcccaagtg tatatttacc acccagttgt gatgagctgg gatcctcctg 509160 ctcaatctca gcttgaagca cttggaggtt atctgcctgc tgtgggtgat tattttggag 509220 caaggtactt catttgcctc aagaaacaga tttgatacca ctactgtgcc cttttggaac 509280 agagaagtag gcaagacccc agtgtgaggc agagtgatgg gatctttagg gacataattg 509340 atgatgtaac tgatgatgat tttggagttt atacatttcc aaagtttcaa aatattttca 509400 cttggttgat ttatctttat ggtgatgaca ctacgtagat atatgccctt cttaaaagtt 509460 acagtaagag gctgggagcg gtggctcacg cctataatcc cagcactttg gaaggccgag 509520 gtgggcagat catgaggtca ggagattgag accattctgg ctaacacggt gaaactccgt 509580 ctctactaaa aatacaaaaa aattagccgg gcgtggtggc gggcgcctgt agtcccagct 509640 actcaggaag ctgaggcagg agaatggcgt gaacccggga ggcggagctt gcagtgagct 509700 gagattccgc cactgcactc cagccagggc aatgagcgag actccgtctc aaaaaaaaaa 509760 aaaaaaaaaa aaaaaaagtt acagtgagag ttgacattga gaaaagggag gcccagccag 509820 ggttatgcaa agacacagta gggaggagga tgggaagttt ctgagacacc ccagtaactg 509880 catgggtcca caaagcacat gtacagtctg ctctatgcac tgcaggtaca gccacgaata 509940 agacaaagtc tctgccctca tggagcttgg tgtctgtcta ctggagcaga caaaaacaaa 510000 cctgcttttt ctcatttgcc tctactgtgg gttccgtgta taactctcaa atgctagcat 510060 ttccatgcat tccatccttg tccttctctc ctctctgcct tttccaggag aattttccta 510120 gccacaggtt cagctatggt ctatgtgctg gagtcataca tttttatctt ctgtgtacgt 510180 ttttctctag acccatattt ttaattgcct taggacagct ctccctggat atccctcaga 510240 cacaactaaa acatcattca attgtactat taataatttt cccttcaaaa tccactcctc 510300 ttctctatag acctaacagc aacactgtcc gtccagctct caaaacctga aatgtgggag 510360 ttgtctttga ctcttatctt tcccatgcat gagcactgaa tcaatcagag tccctagcat 510420 gtcttggact gtggcctccc ttctatcttc agattatctg cctttttaga attatggcaa 510480 taacttaact gcaaagacca catgtgcact tgtgctcttt cagtttgtaa taaatataaa 510540 atgaaaagtg attatgtctt tgcttaacgt ctgcaaaata aaagtccaaa gtccttggta 510600 tggtctataa ggccctcatt atctgacctg cctgccttcc caatctcatc ttaatccctt 510660 acagcctgac actcagacat actagacttt ccacctaact cactcacata cacctatcct 510720 gtatgtcaag attcggcttg accttcatca cctacctatc tgcagtattt ttggatctga 510780 attctctgcc cacattgtac tttcacatac ttcttttacc cttagtggtt tgtacttatg 510840 cctggtctaa ctagattgtc tccctgtaac agacttcttg attcaacaaa gcagctctga 510900 atcagcctga aacctatggc acactgcaaa atggcaaaca ttcaataggt atttgcccag 510960 taaatgttaa tgaaaggaaa aaaattcaaa cttcagttgg aataggatta gagacaagtt 511020 aaaaaaaagt ttcccataga aatcttcctc atcgtaaata tcatcatcct aaatgtcccg 511080 agtctttcca tgggtctaat ttaccaaatc atgaagactc tctttctcac tgtgtatgtg 511140 tagtgggaga ggcagagaca gaacggtttt tttttttttt tgcaagtctg ctctctggat 511200 tcgtttttct ggggatgaaa tctcaggcta tgtagctttt ctggtccctt tttggtaatc 511260 aacaaatcat cagtttctct aggtattaaa aagcctacac ttttgaaaca ccaagaggcc 511320 aaactctctc ttaattgaaa acataattct gcctcttact gaggtctttg ggtgggaagc 511380 ttaaagacag cagtgttggg gcaattggtt tttcttttcc tccctccacc ttctttccca 511440 ttcaagagct gttgctgccc tttctggagg ggagggaatt agaaaaaaag atcctgcctt 511500 acccagtcac tgttaattat tactttgagc cagggtgggg aatgactttc tttcctggaa 511560 tacaccctgc tggaaaccac agctgagatt ctctaagctg gcagcttcca acctctcctc 511620 cctcaacagc ttcaacatta tatggcactc agctgcaggg tgcctggctc caggccggca 511680 gtccatttgt gcagggtagt tttcaagatg gctcatagcc catctctttc agtgaccagc 511740 gtggcctatg ggaaacatac atcttgactc cattattggt aggagtactc tttagttaac 511800 tgccacaggc cagttcagac acgtcttacc ctgagagcct tttcagagtc aggtaccatc 511860 cctgtgtccc ccagcatctg aagatcacag gtgaaggtct ccaagtagtt cacttaaaaa 511920 atacctcagt aggtttaaga acagggaaag ctcccaattc attctgtcag gagtatgact 511980 ctcatcccca aactggacag atatataata tgaaaactac agaccaatat tccttatgaa 512040 tatagatgca aacattctaa acaaaatact agcaaaccaa atccagcagc atagaacaag 512100 gtttatgtag catggacaac tgagattatc ccaggaatgc aaagttaatt caatatacaa 512160 aagtccatta atacaacata ttaataaagg acaaaacaac atgaaaatct tgatacagaa 512220 gaagcattta acaaaaccca cagcccctcc tttttttttt tttgattaaa aaacactcag 512280 taaactaggt ttaataaaag aatttcctca acttgaagca aacccacagc tagctaacat 512340 catactcaat ggtgaaagac tgaatgcttt ccccttaaaa tcaggaacaa gaaaaagatg 512400 tctgctcttg tcacttctat ccaatattgt actggaggtg ctagccagca cactaaggca 512460 agaaaatgaa ataataggaa tctagactgg aaaggaagaa gtaaaagtat ttctgttcac 512520 agatgcatga tctcatatgc aaaaaatact aagtgacaaa aaaagaattt tagaaaagct 512580 acaatataca aaatcaatat acaaaaatta attttatttc taacaccagt gatgaataca 512640 aaaataaaaa ttagaaaata atcatataat taaagtggca tcagtaaaat acttagaaaa 512700 aaattaaaga cgtcaagact tgcacactga aatctctaaa acatcactga aataaagacc 512760 taagcaaatg caaagacatc ccacagtcat ggaacagaaa acctaacacc attaaaatag 512820 cagttatttc tcaaatttat ctaccaattc aactaaatcc ctatcaagat cccagctgtt 512880 ttgcaggaat tgacacaatg atcatataaa aattcatatg caatgcaagg gacccaaaac 512940 agacaaaatg attttgggga aaaaaaaaaa aaaaatggag gacttgcaca tcccaaatct 513000 aaacttacta ccaagctaca gccatcaaga cagtgcggtg ctggtataac gacagacata 513060 tagggcaatg gagtaagact gagaatccag aaagtcttat atttatggtc aactgttctt 513120 tgacaagggt accaggacca ttcatgggga aataatagtc ttttcaacaa ctggtgcttg 513180 ggcagatgga tatacagata ccaatgcact tatgcaaaaa atggatgaaa taggaaactt 513240 cactacattc tactgcatgc tcggtcattt tcaatcattt aggtggcaac actgacaaga 513300 taacagaaag atggaggtaa taacatgtga aaggcaaaat ggtttgtttt tttttttaaa 513360 aatgacagtc tctatcatga atttacttac actccaggca aaggttatta gaagaaaaaa 513420 agatgtaaga aaattcctta actgaaatgt ggaaagagta tcaagaggag accctaagac 513480 actctgtaag aatcccagtg actcctcact gttcaactaa gaaatgtacc ccattatgct 513540 gtgctaccac ggaagcattg gaggcacttt gggggttgat gaagtcttca tggatgaggt 513600 actttaaata tctggtcatg aagagtattt gagaaatatg acaagtgaag atgctgggta 513660 ggaatgcagc gaggaaagtg tgtaacacaa ggccaaattg gaaaggtcag tgagggggca 513720 atctgtggag gcactgaatg cagaggatat taaaattagc aagatagtgt tctagcacaa 513780 tgaaaaggat tggaagaggg agatgagagt cagggagtga aattaggcag ctgctaagaa 513840 tgtccgggtg agtcagagga tcaggacctg taagggcagt ataaagaagg aaggaatgat 513900 gggagaggtt tagggggaaa gaagtgacaa cctgtgacaa ttgaggaatg agagattttg 513960 atgattgggg tgaaggttac atttcttaaa aagaaacaaa gaatggtcgg tcgatagaga 514020 tgcaagatga agaattttgt ttttaggact actgactatg aggtaacaaa gaaatcccag 514080 agacagaggt ctgagcaaaa gatatgggat tggggaagaa tctttgggag tgactgaggt 514140 tgactagagg gaactgggca agaacaggta aggactttaa gcagaattgg aggagtatcc 514200 atctaaaatc tgggtaaact gggatggaaa aacaagtagc cagagaagca acagcccaag 514260 ctagggtgtt gtcaaggtta tagatgttac tgattttggc aatgaggaga ttataaggat 514320 ccttgaagac tgtactttcg gtgaaactac catgcattag tagcctttca cagtgatatc 514380 taccccacac ctgcatcaaa atcttgcagt gcctattaat aaatgccaac ccactaacgg 514440 ggaggggaga aaagacttgg gactctgtac ttgtaaaacc ctctaccctc cccaggcaat 514500 tctttacaca ctaacactgt tgaggtaaaa ggagacaagt gagggagcaa atggaaggtg 514560 tgtttttgga ttatacagtg gctcatggaa gggtgggagg ggtacagatg gcccttagac 514620 actggcggaa agtcagagaa aaaaaattac agtaagcagg taaagggatc aagactacac 514680 agggactagt cttgggacga catttcttcc tctgacagtt tgtatggaat tcttgagaaa 514740 aattcctcga aggggcctga aatctcagaa tggtcatgtt tttaatggga atagggagtg 514800 atgctgcccc attacaacca tctgttctaa cagaatgtct gtaccgagga gggatgagta 514860 acatcggcaa gttctgttcg aagccttttt caagtttctt tttgatatgt atctatctat 514920 ctatcatctc cctatacaag caagcatccc caaaagtagt tgtctcagga aaccagggtt 514980 aggatgacca gctcatttgc tggagctgcc aaggtccaga aaagtttggc tgcaggctgt 515040 tttcatgttt tatgtatgtt tgaaatgttc tataataata aaaggttaaa aaagtttaca 515100 tttatttgga aaaccagtta ctttagttta tggttccttt ttttccctcc agagcttcct 515160 ggagattgag gtctaattca aagaaaacca aaatatataa tagagtacct gggcaaaaaa 515220 agtactttta taacataaca tttggggtag aggaagtatc cactgtagtc aaaatgtcta 515280 tgttttgctc ttccttattg ttcagggaca ttccattaaa tagtaatgaa aaggcagcaa 515340 aagtaagagg agtgacaaca tgcccggcat aattaagcaa gctagagcag ctattctgtg 515400 caaccgacga ttttttttct ctaaaatttt aagggtaggt tcattctgac tctgttaaaa 515460 gtctacttga tgtgaacaac tctatatctg ataacctatt tcaattacca ctttaaaact 515520 tgtcatatgg atacgttatt acaattgtag aactttaata aataccataa taataaaact 515580 tgagaactga agagcacaca tttcttcacg aatttattat ataaaacgcc ctcagagtat 515640 ttaatttctc ctcactttaa ttacacatta agaagcacag tggatgagaa gcctttaaga 515700 tgactacagt tgcacgaagg tccctttcat caaggtagcg tatgtaccct aacagtgttc 515760 taaaggctgg cccagaaaaa ccccatgtta ccttatcaca atatggaaag cattgtcttc 515820 tttttccact aaattaaatt atggtgaaaa gtgccacagt tttatttagc attatggtac 515880 ataacaaaca gttctgtctc aattatgaaa aaaattaatt aaaataatcc tgaaagacat 515940 cctttttctc cccccaatga tttgaaagct gcatttttcc tgccaatttc aaacaaacaa 516000 atcatcaggt tgatctacag taatcagtta aaacaatcag tcaatcaatc aatcaatcac 516060 caaggcacaa gctcagcaca ttagctatag cttgtagcaa aaggatatat caatgtctca 516120 ccttagttaa aaatacataa tccttttatt ttataatgca ataaaagaaa ttaacaacat 516180 cacatacaca gaagactagg aaaggggaaa ctacttactt ctggaaatca gtaatgtaaa 516240 cctacttgta cttttccata gtacatgaaa gtaacgttta acatgttttg aattaattaa 516300 ttaaatttaa tctgtggggc tatacaatgt aattcttagg agtaatagtt tcattcattt 516360 ccaggtcagc ttactgtatg attaagtaac acaaggcaca gtagccatct ttttcattat 516420 gttgcaacac tgatcacgtg cctcgataaa atggctgatt caacaagatg atggcaacac 516480 gaaggggaga ctttggattg tctatttaaa atctaggtaa taagtaagta attaataaaa 516540 actctatctt aagtgcactt tcacatgctt tttgtttata ataaacaaac aacaaacttc 516600 ctaactttgt tgcaataggc ttgactacca tttcatttgg ccaaatgcac tttccccagt 516660 aaacttaaaa caacaacgag aacaacaaga acaaaaatcc ctgtcctttc atatactaag 516720 aaagaggatt ggctactgaa acagttcatt gcaagacaca tgaagacgac atactgtggc 516780 atgagttgtt tttgttttta atttgttgtg ctgttactaa agttctgagg gctgcagtta 516840 aaacattcca atttctccct tccttccatc tttctttatt gattgattct caagattttg 516900 cacagaaaac tctttggggg ctagaacagc agtaattgca tcacactgtt ttcaagactt 516960 caagtttcaa aagcaaatca ttaaaaaaaa tacagttcct gatttgagtt agatacaggg 517020 acaaaaaagt agcacatact tgaaggttac gtggtctaca aatggtggca atattttcct 517080 tgggagagta gttctgttgg tatatatttt ttaaatactc aaaaggctca acctcaagca 517140 gtaataaaca caagcaaaag tgatttaacc cttaaaataa atattcagaa aaacctctct 517200 gtacatacaa gtgaaagaat atgtaacact ttcacgcaaa aaaataatta taataataat 517260 aaaggatttg ttcatatatg tagctgaaat ctgctgttcc agcccacatg tccccaataa 517320 agaagggagg cacagacata ggtgactact gtggttgact atcttacagc ctttttgtac 517380 tgggacacta tcaccaccaa aaatttatcc ctcgttatat ttttaaaatt ttttaaattt 517440 tttctttttt tttccttcct tttttttgtt ttattttgtt ttgttttgtt ttacagcatg 517500 ccaaatcctt tggcatacgt gatggccttc aacaatctct ctttaagttt ttctttgctt 517560 gagtattccg gaagtaaaag cacattaaag caagtatgag atgtaggtaa cctaaataga 517620 gaaaagggga aaaaaacagg aaaactgtaa gtcatgggaa atacacttag aattaaatgc 517680 tcctattttt agattgtata tagttgagac ggtctgcaat gcaaactata cattaatgca 517740 aatcataaac tttttgttgt gtaactacca agttgccttt atcctataaa ttactcaaag 517800 ctagtgacga tgataagata ctgtatccat tgagttttta ctacataaca gataccattt 517860 taggtactga attcttacag ttcatttaac taaatctttc cacaacaaaa ccacagagag 517920 gacatcagta aatgcacttt agaggttagg tcactgagaa gtcaagtaac ttcctctaag 517980 gtggagaaaa tactcaaacc tgttttacaa gactgcaaag tgtgtgctct taaatgctta 518040 ttagaaacac tgctggcaat atgactaaga aaatgatttg ataacaggat tctagcacaa 518100 tcaaatgata atcttccgag cctcaatgta accattctaa atagatgatc atgttatatg 518160 gctttcaatt aacaagctgg gaatcaaaaa agtaaatgaa tcacactaat ttgattccaa 518220 accaatgtga gccccataat aatttttaac tagggcaatt tcttaaaagt ttcctcacac 518280 aatgacagca aagtattttc tcaattgtct aatatgattt ggggatttgt atataaaatc 518340 acgaatgtgc tcagaaacta taaagacagt tcatatgtat gtgacgagga atgcaaggtt 518400 ttcggtaggt atacagtcac aagttaataa ttacctacct ttctgtgtct gggccatttt 518460 tggctataat catctttaat tttcctagtc ctcccacagg tgctctgtct gtgcccgttg 518520 taaactgcaa gaagagtctt ttctgttcat ctgtaaatga atgaacgatt tcccagaact 518580 ccctaatgag aaaaaataca atactggttt cagtttggca ttcattatga ctggtactaa 518640 cataagctta tgatttgcat taaaactata ttaagagaca acttggaagt taattatcag 518700 gatagtatca cttctggtga tttaaaaatt tccaagcaaa tttatcctga acagctctga 518760 atacgtaaaa atttagatta gattacaata tagtaaaata ttagtactac aatagtaaaa 518820 aattgagaaa acccaagtgt gtagtaacag gaagtgacta tttaaactat ggtataatca 518880 cattatgcag tcagtaatga gcaaaagaca aaatcctatg aattgaaaaa gactgaaatg 518940 aatatttgga aaaattaact ccaggtgcct ttgggtatat attttattta tcctttctcc 519000 tttattctcc tggtctactc atcctttaac tcaactttgg gaggaaaaag tgatacagat 519060 taaggacaaa agaaaaaaag accccctgcc ccaaccaact ggccccaaat gcaaacaact 519120 acatacctaa tagcagtaat acaaaagttc aatttttata tgaactagaa tactttaaac 519180 aagtaatatg tgctgtgtat ggaggaggag aattattctg acatttctgc cacctgcagt 519240 tattttaaga gaatgattta tcctgtggca ttcctaaaat ctatgtaata aaagctatgt 519300 tttaatgaca cttatgttag tttgagttct aaaaaacgaa atacaagctc ataaagtgca 519360 atcttgaagt ttatttgaat aatcaggcat ctataaaaca tatatacact agttcatagc 519420 taaataaatt tttttttttt tgagacagag tcttgctctg tcgctcaggc tggagtgcag 519480 tggcgcgatc tcggctcatt gcaagctccg cctcctgggt tcgcgccatt gtcctgcctc 519540 agcctcccaa gtggctggga ctataggtgc ctgccaccac gcctggctaa ttttctgtac 519600 gtttaagtag aggcaggatt tcaccatgtt agccaggatg ggtctcgatc tcctgacctc 519660 gtgatccgcc caccttggcc tcccaaagtg ctgggattgc aggcatgagc caccgcgcct 519720 ggcctatagc taaataatgt taagattaaa aaattaaaaa aaaaattaaa agtattttta 519780 gttgcttata taatataaaa tgcattttaa tagttattta gaaagttctt tccagagcca 519840 ggtgtggtgg ctcatgcctg taatcccagc actttgggag gctgaggcca gtggatcacc 519900 tgaggtcagg ggttcaagat cagcctgacc aacgtggtga aaccctgtct ctactaaaat 519960 acaaaaatta gccgggcgtg gtggcagatg cctgtaatct cagctacttg ggaggccaag 520020 gcagaagaat tgcttgaaca tgggaggcgg aggctgcaat gagctgagat cacaccattg 520080 cactctagcc tgggaaacat tttgagccat ctcaaaaaaa aaaaaaaatt tcatctcaaa 520140 aaaaaaaaaa aaaaaaattc cagaatgtta gcagagaaca tcacacatcc caaaccagta 520200 attacaattt tctacctttt gatattctaa tatcccaaca tactattttt attaccaaaa 520260 tgctggcatt tttggtgctg caacaccatt tatctgaaat aacttaaaag ttttattaga 520320 attcttggct ttctccaatc tcttgccact tcccttccct gcccctttac aaatccacca 520380 gtcagcaaga gaaaacaaaa aagaaacaca caacaacaga aaactggaca tgaaacttgc 520440 aggagcatct ctcaggtaag gaggagagga atcggacccc agttcatgat actccttttg 520500 gggaggctga caagagaaaa caagtctgct gtagcacaga accctccaac atagcagaaa 520560 agctgccctg cagtgggtgg taataaagcc tcctcacact gcaggagggc tctgaagctt 520620 aactgaacca gctacaccta aggaggtaga ccaaagagca ccaccgaaga acagagacag 520680 accctgcagg aagtggcaga tcagcagtgg tcacaatgac cagtctggct atattattac 520740 ggagctgttt ctttggactt ttaaacgaaa cctttaaaaa ttttatacaa tgaaaacagg 520800 gaacaaaatg catctctatt cctataagtg ttatgtgtgt tacattaaca ttttgaatta 520860 aacaagaatg catatattta gaaagctgaa gaaaacacga agaagcttcc aggtttccac 520920 ataaaagtgg tggctgtatc gatcacatcc tactcacatc tctaaaaatc tacccggatc 520980 aaaaagggga aaataaaaaa aaaacctatg acttaggtct agagtaaaac taggagacag 521040 aacaataaac tccaaatacc aaagaagtgg ggaaatgagc agggtccagc aggagctaca 521100 tcgaagagtg gcttgtgcgg aatcatactg attagggatc acccaaggcc agaccccacc 521160 ccctccacca cctgcccctc aacagagcac tactgagtgt aggttagagc actggcaaca 521220 gggtggttaa aggaaggact acagaaaagt acttgggtcc agcaatggca ggctcaggaa 521280 ggcaccatgc atgaaaggaa ggggggtacc ttcaaaagca gaagtgtccc ttaagcggct 521340 gtaaaggggt ggaagcagct aatgaaaaag agtcttcatt aagctacatg gagctgaaaa 521400 atcagaaagt ggtgattctg cccttactaa agcaacagaa gagggatccc ttcaaccaag 521460 acccctaaag ccacacaatt cctccctgct ccaccatgag gtctagtaat aacaggtcca 521520 gaaaaaagta acatctgtta tagaaacata aacaagaaaa acagaattcg gaagtctaaa 521580 taaagttatt atgggaagag tctggcgaat gagaagcaaa actttccggt agacaaaagt 521640 agaccagaaa aattcagtca taaacaatgg gaaactagta acaccacatt ccaacacaaa 521700 aggagaatgc agcagcagac aagacagacc accagtgatg agaaatacaa attcagaaag 521760 aaatgagcac atcttaaata aaaataagaa tactaaaaaa tactgaagaa atatgcaagg 521820 taactttgga aataaaggct aattttatta taaggtgacc aaagaagaag cagtatgact 521880 aaaatttcta ctgaggacag actctagaaa attaaaaaac aaagaaaatg aataaaataa 521940 acataactaa agaaatgcat atcaaagcat aataacgaaa aagattaata gctaactaca 522000 taaacataaa acctttcatt tggcaaaaaa atcctataag caaggttaaa agacaaatga 522060 caaactggga aaaaatattt gcgaatttac cagcgttaaa ggactaatct ccttaacata 522120 taaagtttct aaaagtgaag aaaacgacca gctgagcagc aaaatgagca aaagactata 522180 taaaactata aacagctcta caagaaaaaa tgtccattat cattcataat tgaggtaagc 522240 tcaaaaattg taactatagt aaaataccat ttctcaattg gcaaataagt aaacatccac 522300 atttaacaac acattctgtt tggaaagttt taagaaaaga gatactgttg taaactgctg 522360 gtgggaatgc aaaatgttat ttttctgtga aggaggattt ggcagtatct agcaaaatta 522420 cacatgcatc taccatttga tgcaacaatc ccacttctaa caatttatct taatgatact 522480 ttacatatgt acggaataat gcatgaacat taagaggatt cactgtgaca ttagtactaa 522540 cagcaaaagg ttaaaaataa cctcgatgcc cataaatatt gataagctat gctgcatcca 522600 cacaaaggag cagtattcag tcatacaaaa caaaatggaa aacacctctg caataatgtg 522660 ggatgattct caggatacac taggaagatt attttcctag ttctgtcctc tgataaggcc 522720 tacaagcagt aacgttcaaa agcaaaggcc atactttgca tctaaaatct gacttctaaa 522780 tgccattctc caacaattta ttggaaaaat aacttattcc aggcctgaga atgaatgttc 522840 gagattagtt agaaatctca aaatctaata gggtcatttt aaaagcacac gatagctaag 522900 caatttgaat atcatttaga gtaatgactg tgaaacgtat taaatacaaa aacattcatt 522960 agttcgtaat attcaaaaag gcagcaaaaa ccaaccaaaa aacaaaatta aattgtcact 523020 attaaaatta ttacattaac tccttactct aaaaacctta aatctatttt atcatgcctt 523080 ttctgtagaa ctgtttttca aggtaatcaa atggcaccca atgatgagaa aaaagaatgc 523140 caggtatata tgtaggacaa gcagatggaa attttttttc cccaaacagc cattttgcaa 523200 tccccaatga gataacagat taaggtaatg atactgataa atacgaaaat caggtgaagg 523260 gcaggtagca ggttctggaa agatgatgat ggcaacgaca tagttattat tattattatt 523320 ttttgtttta ttccctccca acctccccta caaaaacagc aaactgaatg agaaaaccaa 523380 agacccagag acattatcta caacaaaacc atgaaccatt gcatataatt ggacagaaac 523440 aaagctctga caactacaag actggttagt aaggaagcag atgcaaggta actgactggg 523500 tttctgacag ccctgagaac actgccaacc cactggaaag cacaggccaa tctgaaaaca 523560 gggcttaaag ttttaaaaag ttctacagga tctaatttgc agatgattac aaagggatca 523620 tgatgtagta agctctgggc ccttaaaaca cccgaatacc aaacccccac cagaaacaaa 523680 ccttgtaccg aggaaaaact tctgggaata acttccgaat ggaccaggtc agtaataaaa 523740 accaaaaaaa agttcaaata tatgtgtggg atagaggagt aaagaaggca gtttcagaaa 523800 gcacaagggc atatttttga ccattttaca aaaacacaga cttctcctcg tccctaaaaa 523860 gcgaaaaaag ttatcctggc ccatctctcc ctcgtccaag tatgagaaac tcatttcact 523920 cacacacaca cacacacaca cacaaataaa taaataacag aacagagtga aacagtgtaa 523980 ttattagaga aaaagtatgt gcatatacat gagaatggtg tccctacaga aaatcaaagt 524040 acatgaaaca atatgcaaat aaaacatgaa aactgtaaac aaatttcaaa ctgagctaaa 524100 aagaatttaa aaaataacaa atcattagaa atgggaaatt tctgaatgag ggtaactgaa 524160 aaaaaggaag acatgacaca actaaggagt aattagaaat gcaaggaaaa aaatcccatc 524220 aaatacaaag aaactaaaac taaactagaa gaaacataaa ggtgaataaa acagaacaat 524280 aataccagaa cctgaaggca gaagaaaaat cttaaaatca aaaagaaaca aacccatgct 524340 tgagactctc cttgctggtc cagagccaca gtgctgctgt gtactggcag gaggaattct 524400 gctataattg gtcctggcag tgttcacctt tcctgcaagt gttccacagc ccagggacac 524460 aatgtggtca ggagcactgc caggaacacc agcaaggggg agcctgccac aacaggcaca 524520 aggctcagga agcactctcc agcccacgaa aatctagtgg gggtcctctt ccctcaccca 524580 aacacactct gcgcagctca gcctggagaa ggcccctcaa gcagcactac taggaaccag 524640 tgcgagcccc agtggactga gataaaagca acaaaccaaa acagcaccat aaagcctctg 524700 aaaaatggtc actggaacca cagctcacaa atatatgcta gtacctacat gctatacctt 524760 aacaggttac tactgaagtt aaaattttta aaaagtacag agtctcctga tataataact 524820 aaaatgtccg agacacaatc caaaaattat ctgtcatacc aagaaccagg aaaattacat 524880 gaaggaaaga aaacgccaac actgggatga gtaagatgct gaaattatct ggcaaggatc 524940 ttaatgctgc catcagagaa atgatttgac aagcaattac aagttctact gtttcaaaaa 525000 cgaaacaata gaaaatctca gcaaggaaac aagatacaag gaaaaaaaag caaatggaaa 525060 ttatagacct aaaaaataca ataggagaaa aataatcatt agatgggctc aacagtagag 525120 tgaagatgac aaaggagaga aatctgaaca aaagagagaa aatagactga aaaatgaacc 525180 atgcctcagg tccatgtgga acagtaacaa atgactcaac atttgtatca ttagaggcct 525240 agaatggaga aaagagtgac gctgaaagaa cacctgaaga aataatggtt gaaaattttc 525300 catgtttggc aaaagacaca aacttacagc ttcaagaagc tgagcgaacc ccaaatagca 525360 caaataaaac tattctttgg gaataaaggg aaaataaagt catcttcaga aagagaaaaa 525420 caaaaagaat ttctcactag cagaactgcc tttgaagact ggctaatgga agtaataaaa 525480 gatggaatct tggaaaaaat aatggaaata gcagaaacat gggtacatac aacagagcat 525540 cactcccttg ataagttcta taagtcatat tggataactg atacaaaaac tgtaatagca 525600 ttaatcctca aaacaatact atttaaaagt ggggaaagag acccaactga aattaaggtt 525660 tccatatctc attccatgta atggtattga tggcagtgaa tggtggtaag tcacattatc 525720 tataatgtga tacccacaat gaccgtgaaa acaactataa aaaacacata gaaggccagg 525780 catggtggct catgcctgta attccagcac tttgggaggc tgaggtggac agatcacaag 525840 gtcaagagtt cgagaccagc ctggccaata tggtgaaacc tcatctctaa taaaaataca 525900 aaaattagcc aggtgtggtg gcatgtgcct gtagtcccag ctacccagga ggctgaggcg 525960 ggaggattgc ttgaacctgg gaagccgatg ttgcagtgag ctgagattgt gccactgcac 526020 tccagcctgg gcaacagagc gagactgtgt ctcgaaacaa aaacaaacaa acaaacaaaa 526080 caaaacccaa acactaaata aatcaagggt cttaaaaatc ttaaaaaatg ttcaagtaat 526140 catggaaggc aataaataaa taaccataaa cagaagacag aaacagaaaa caaataataa 526200 aatggcagac ctctccctaa catatcaata attaccttaa atataaatgg tctaaataaa 526260 aaaattaaaa ggcagagact aacagttttt attaaaatga caactatatg ctgtttacaa 526320 gagattcgtt tcaaattcag caacacagga tgaaagtaaa atgatagtaa aagacagatc 526380 atgcaaacat taatttaaaa aaaaacaaat ggttacactc atatcagatt cagagcaaag 526440 aaaatcgcaa aacagaaaaa acttatataa tgataaagga ccaatcacca agacatagta 526500 attctaaatg ggtatgaacc aaatgataga gcctcaaaat aaatgaaaca aaacctgata 526560 aacagataaa tctcagaagc agacctatat aaatattctc aagtgatttt taacgtatgt 526620 gaaaaaaaca attcaatgaa ggaagaacat acctagaaaa tacataagga acccttaaaa 526680 ctcaacagta aaaaaccaaa tggactcttg gtttttaatc ccagagaaat acaaactttt 526740 tgtttacaag taacatcaca gttaatggta aatattatag tctctctcaa taaaatgagg 526800 aataaagtaa gaataccttc taccaaaggt tctagccagt gcaatagagg aacagtaata 526860 aataacataa acattggaaa gaaagaaacc tgtcttgatt tgtagatgac atagctgttt 526920 actagaaaac cctatgaaat ctactaaata actactagaa taagtcaatt tagaaaggtt 526980 ataggatata agatcaatat ataaaaatcg attttatttc aagatagtaa taaacaagtg 527040 aaaagcagta tttaaaaaat accactaata gcattagaaa catattttaa gtttattcct 527100 aaccaaagag tacatgattt caacattaaa aactataaaa cagtgctgag ataaactaac 527160 aaacatctaa ataaatggag agacgtacgg tgttcaagga ttggaagaat atattgttaa 527220 aatgtgaatt ctctccaaat tgacctgccc cagtcaaggc aacccaaatc aaaatctctg 527280 caggctttgc ccttttgttt gtaaaaatta actgattcta atatttatat gcaaataaaa 527340 gtcaaagcaa cctaatgaaa aagttgtggg actcacagca tctgatttga agctgcagta 527400 accataacag tgtcattttg gcaaaaggac aaaacaaatt aatagaacag aatggagaat 527460 ccagaaacac ggctcacaca cagattgatt ttcaacaaag gtgcaaaggc aattcaatgg 527520 ggaaagaaaa gtctctttaa caaatggtac tggaacaaat aaataaaact atttagaaaa 527580 tgaatgacat ccactgtcta acagcatcac aaaattttat tggtggtgga tcacagattt 527640 acacataaaa gttaaaccta tattacacaa ttagaagaaa acataagata tttgtggctt 527700 tgggctaggc aaagatataa aaggacataa aaaaccataa aagaaaaaat aaattagacc 527760 tcaaaaaatg aataatttct gctcaccaga agacacttaa gaaaatgaaa acttggagaa 527820 aataatcata aactacttat cagaaatggg ccttttatat agaatataca gtattcccca 527880 cttacccatg gggaatacgt tccaagacct ccagtgatgt ctgaaattgc aaatagtact 527940 gaaccctgta tatactatgc atgatttatt tttccttctt cacaatttca tagatacaat 528000 actcattttt accatagatt ttagcaacct caacatatga tttttaaatt ctttccttaa 528060 aggaagcact ttccagcttc tctttggcat atatattcga atttccaaca tcactgctct 528120 tgtgctttag ggccattatt aagtaaaata agggttactt gaacacaagc atgtgatact 528180 gcaacagtcg atctgataac cagtagacta aaagtggtgg gtagtctaga caacaacgat 528240 atactggaaa aagggataat tcatgccctg ggtggaaagg tgggagattt caccatgtta 528300 ctcagaatag catgtaattt aaaacttaag agttgttggc tgggtgcagt ggctcacgcc 528360 tgtaatccca gcactttgga aggctgaagt ggaagaattg ctagagtcca ggggtttgaa 528420 accagcctgg gcaacatagt gagaccctgt ttctacaaaa aaataaccaa ctaaaaatta 528480 gctgcacacc tgtagtacca gctactcaga gggctgacgt aagaagattg catgagccca 528540 gatactcaga ggactgaggt aagaagattg catgagccca ggagtttcag tttataacaa 528600 tctgtagtca tgctactgca ctccagcctg gatgacagag actttgtctc tttaaaaaaa 528660 aaaaaaccaa cgaaccaacc aaccaactct ccctgccctg cacccgccaa cacacacata 528720 catcaaaaac cctgaattat tcatggaatt ttctacttaa taaatatttt tggaccactg 528780 ctgaccaaag ataactgaaa ccaaaaaaaa gcaaaactaa ggataagaca tactgctata 528840 ttttaagaaa atatctatag tcaatagaaa tacaaaaatc caatattaaa aatgaggaaa 528900 agacactttt agttaaatat gcacctgcta tatgctttgg aaactccact cctacatgtt 528960 tgcccaggag aaataaaaca tttccacaat aagactacac agctttattc acaatagtcc 529020 caaactggaa acaatccaac tgtccaccaa caggtaaaaa aaaaacactt tgcgtattca 529080 tataatgcaa cactactcta taatttttta aaaggcacta taaatcaatg caataacatg 529140 gatgaatcta aagagtcttc atgcagtaca agtacataag attccattca taagaaattc 529200 tagagcagac aaaagtaagc tacagtgaca gtaattagga cagttattgt ctgttctaat 529260 gggggatgga gattcactgg aagggaaaac atgggaactc tgtgctgatg gacatagtct 529320 acaccttgac tgaaatatgg ttacataaat gtaattttta aaaactaacc caattaagcc 529380 ctgggtattt cactgtattc aaattttacc ccacacaaca tcgacaccac cattattacc 529440 accacattga taacattcag agagcagtta gggaatcaca ttattttgaa aattagtaag 529500 taatgggaaa gaattaagca ttatcgtata tgatatgtac atatttatat acatgtatac 529560 agatcctata tgtggatctg taatttaggg tagtcataga gttgatgaga aagagttttt 529620 cttaagaagt attacaggta ataaaggaag gaggaataaa gaattcgagt atcacaattt 529680 tgtaaccctc aatgaattag cagatctagg caatcagaat ccacgataaa aattactaga 529740 aaagacagaa agcgagtgag acttttaagt tattcctaca aaccaacatc tatgaagtat 529800 ttgggaagga aataaactct gaatctgttt ttcgtttttt tgagatggaa tctcactctg 529860 ttgcccaggc tggagtgcag tggcacgatc taggctcact gcaacctccg cctcccaggt 529920 tcaagcgatt ctcctgcctc agcctcccga ggagctggga ttacagctgc ctgccaccaa 529980 acccagctaa tttttgtatt tttagtagag acggggtttc ccccatgttt gccaggctgg 530040 tctcaaactc ctggcttccg gtgatctgcc cgcctcgggc gtttttgcat gtattttttc 530100 aggtgctgaa aaagctctcc ctgatttcat ttcttgttga ctgcttagag acatctttcc 530160 aaatgtcctt ccttgtcact ttttcaaagt taggagcagg gattgcacgt ttttttgatt 530220 ggtaattttt gtttcaaagg tttgattcag attcagagtt gattttgcta ggtatggtgg 530280 ctcacgcctg taatcccagc actttgggag gccgaggcgg gcggatcacc agaggtcagg 530340 agtttgagac cagcctggcc aacatggcaa aacccttatc tctactaaaa atacaaacat 530400 tagccaggtg tagtggtgtg cacctgtaac cccagctact caggaggctg aggcaggaga 530460 atcacttgaa cccaggaagc ggaggttgca gtgaactgag actgcgccac tgcactccag 530520 cctcagtgac agagcaagac tgtttaaaca aacaaacaaa aaattaacaa aatcttattt 530580 ctagtggttt acatattaat gatgctggca acttttagtt gaaatgtatt aaacagcctc 530640 gcagttttta tttttatgaa ttctgcatac aataaataaa taccaaccaa aatatctata 530700 caggcatacc ccagagatac tgccggttca gtttcagacc atggcaaata aagtgattat 530760 ggcagtaaag tgagtcacac aaattttttt gtttcccagt gcttataaaa gttacgttta 530820 cattatactg tagtcaagtg tgtaacagca ttgtctaaaa ataagtacat tatcttaatt 530880 taaaatcatt gctaaaaatg ctaatgaagt gagcacattt tgttggaaaa atggtgctgg 530940 tagacctgct tgatgcaggg ttgccaccaa aaaaactcag tatctgcaaa gtgcaataaa 531000 gtgagatacg cctgtaatgt cttttttctc ttctgttatt acaagcacta ctttaagtct 531060 tcaactaccg aatacttgta gactatttaa tgaattaata ttttcatcat atttatattg 531120 agaaaattaa gaagctgaat ttagttagaa aaggtttaga atatcatcaa ctcttgagga 531180 tgagttggaa gctactttat ctgtcatttt tcacataaca ctagtttgcc cttcaaatca 531240 tacatttaaa aatgatctta agatacatac caagtaggga ttatgttgtt ataaaaagct 531300 agaagtaaaa ttaagacttt aatttcaaag ataatttctc tataaagaat agcacaagat 531360 atgttcaact attctcagag atgcatcaag atatgacttt ttttcctact agaaattata 531420 tctatgatca atcatattac agagatattg ctgttatact ccttgtgact gatgaggggg 531480 gtttttccta tcaccatgtt atcccaaccc tttaatgaat cacctttgaa actcagaaca 531540 ggtagcagca cagaggttgc taagagtaaa tacattcacc actgctgcca gaaatgacca 531600 acggtgcacc agaaagaaga aatactggtg aattcccaca taccacgacg aacaacctta 531660 taaaataaca gaacaaatga atataaagta acatacagcc atcccttggt atatgtgaca 531720 gggattggtt ccaggaccac gtgtgtatac caaaatccat gcacgctcaa gttctgcagt 531780 tggccctgtg aaactggcat gtatgaaagt cagccctctg tatatgcagg ttctgagtcc 531840 caccaatact gaatctgctc ttagttgaga aaaaaaatct gcatgtcaga gggcccatga 531900 agttcacagc tgtgttgttc aagggtcaac tgtaatataa aaataacatt tattgctaga 531960 tagagttgat attcattcta gtgtttatat acttgagtct tagagcaata gcctttggag 532020 acaacttcca ggaaggtacg tgtttgcatg ccttctcact gcaatccatc agtagctgcc 532080 acttgaacca gtcttagcag gggatgggga agcctatgtc tttcagaatt ggatgatgta 532140 gtacacagaa gtagacagta gagtagtaag ggcatttgct taaaagcaga tagaactggg 532200 aacctctaca tctttctgtg agaattcagg gcttagtttt ttagggtgta aaatggaaat 532260 actagtatgt atctggacat attatcttaa gaattaaata aaagactacc atttcactca 532320 aaaagtgctt gatcctggga agccatgtaa cagttcacaa atgcagagtt caaaagaaag 532380 gaaaaattgc agacatggta gccttatttt aattatcttc taaccagcag taagcatact 532440 ctaaccagtg aggaatacta gataatccat acgccaaatg caggagatta catgagactt 532500 atatataaca acacttcatt catgaaataa atcacaagat tagctctgaa aaatggtgat 532560 tatattacaa atacaaatct aagtatatag atgacaattt gtgagtttgc ttatttggga 532620 attagtacct agagataaag gtctgaagca aaatcacaca cccctttggt gaatcaaatc 532680 ttcctctgaa gaactaagta cctcacctaa tcagaacaga gtccctggta tagccaccgt 532740 catattctgt agtttcttct agtgcttgga aatctagatt ctgcaaattc aagaaaatat 532800 gtcttagtta tctgctatac tactgtatca ttacaaacaa taaatcgata catgactttt 532860 tgcagacacc tgctttctta cccggcttcc acatataagc aattcaattt cttctggtct 532920 gaataagtac tttaagggag attcattggt caccatatga aaacctctcc gaaaagcctt 532980 gaactgtttt tctactgatt tattgagaat gtagtcagaa taaagattga caaattcctg 533040 tagaaaacat taatcacaag aacttcttat aatatgctat gcaaacaaaa cacaagttat 533100 tgggctgcat agctttttaa tttttccaag aaaaaaacat tcaagaatat tcttaaaaat 533160 tcaattttac acctacttct taacaatttc acaattctct gttatagcca atattaagct 533220 atgaaaaggc catatacata aaactgtcaa gaatattctt aaaaattcaa ttttacacct 533280 acaaagaaaa ctacttctta caatttcaca attctctgtt acagccaata ttaagctatg 533340 aaaaggccat atacacaaaa ctgtcatact tataaatgtc aatttcgata atgtattaaa 533400 cagaactgaa tataaatgct ggagacgcag aaaattcttt aggttctctc aactaggtat 533460 gtaaacagac acatttaaac catgtatcca tctatttata aatgccaacc gttttaagag 533520 agtacaatat atttgattta agcaaaccag gaagtcccaa gttttctacc atagaatatt 533580 tggtaagctg cctactgtat ccagttcagc aaaaatgtgg aagtactgac tgacacataa 533640 actactgtat caaatcataa aaggaaaatg tgctttgtac ccttagtgtg tataatattt 533700 aatcaaaaaa ttatatcaat ataaacatgt ttcttaaagg tatactatat atttgtcata 533760 attttttgct tgttatgttc tgggttattc ccattcccga tgaacacatt ttagtcaata 533820 gaaacccaaa tctgacgtaa agtatacttt tcagaaatgt atttttatca caaacaggat 533880 atacatgtgt aaattaaatg taatttttat ttgttctgtg ataaagacct taatcatgag 533940 gttcctgctt acagcttaat acaagaaaca ccctgcttct tgctttatac tacaaccaca 534000 cttagctatt aactatctcc tgcttcatgt cctctttctc taaaaggggc tttagtgccc 534060 aactgtgtgc tttcatacca acttatatcc aagatttaga aaagtggact ctagcattta 534120 cataaactta gttacttgtt ttttttttgt acagactata ttagatactt ctttaaaaat 534180 tataagcata catgctttga aagtgttaat gaagagacaa aatgtgacat aaaaacattt 534240 attaccttcc tgttttcatt tgtaattgga attttatcac cattttcctt tagatcatac 534300 atcattgggt taccaaaaag atctgtctgt gatatctgga aagtgatcat catgtcatct 534360 tccacattcc cttcatactc caataaatct tttaaactct gatatagaac ctagcaacca 534420 gaaatggtaa attgaggcca ccatagaact acaaaataca acaaataatt tatatcactc 534480 ttcttagaag acaacaaaaa tcttatcaat aaaaattgta aaaagtgtag acagtatccc 534540 tccagtcccc caaatagttt ccaacctata aaagaaagat tgtcagtcac tgtgatgtcc 534600 cattctctgc tgagaaaccc cataccacca atttagcaat agaattcaca ctgtgctcta 534660 tgagaaattc tgtggtgtct caaggtgggg gtgggggtgg taggagcagg cacactcgtt 534720 gtaactacca agacccttag ccagggctac tctgattttt acctatctct taagatttca 534780 ctaaaacaca aacaaaatgt ttagaaacac ttctctatga aatcaatctt acaaaagctt 534840 cgtgctgaca gcaatatata aaaatgtccc cctttgagtt tttaagtgtt tctggtactt 534900 cggtcagatt aaaacatttt tatcttattg ataagagtat caacaaagat tctaaacaaa 534960 aactttaaaa ttttgacata aattaaattt ttgcatttaa ataaaatcta agagactgaa 535020 ttaaaaaaat gacaaagaac ttactgggtg agagtctccc aagtcacgaa aagttccttt 535080 tttccccatt agcttcctgt agacaaccat gggaaaatgt acatccagta tacagttatt 535140 gtaaatagcc agacccagta ctatgccaat cagagtaaac tgaccctcag tttcaaaaga 535200 agatggatta aaccaaaaca attttgtaga ttcatcgtat gtgaacatac ctataagaaa 535260 tgatttttaa aaatacatta cttttgtatt ttattaagga ctgatgaata atacaaatat 535320 aaacttaaaa taattatgca tataaaacat ttaaaatata tgtaattagg catgcaacat 535380 tgatttctat tatattagca cttgagaaaa caatgtccac atatatctgc tataaattgg 535440 ggtgaatggt gatatgtaat tttatgaagc caaaggaata aagtagtaag taatttggtg 535500 gcatcgggta gaaaaatacg ttaattaaat tcaagctttc taattttcta ctaacacata 535560 agaaaagtta tattcatgct ttatccaccc atagctgaaa aataaacata aaaaaacaaa 535620 aaatggctac atttccaaag tgtttcattt ataaaaatat aattacttat atctgtacca 535680 cacgtactat ttttgaaaac aatttttcat ttttttcctt gagatggagt ctcgctctgt 535740 tacccagggt gggctggagt ggcacgatct cagctcactg caacctctgc ctcctaggtt 535800 caaacaattc tcctgcctca gcctcctgag tagctaggac tacaggtgtg caccaccacg 535860 ccagctaatt tttgtatttt tagtagagaa ggggtttcac catgtttgcc aggatggtct 535920 caacctcttg acctcgtgat ctgccagcct cagcctccca aagtgctggg attacaggcg 535980 tgagccacca cacctggcct aaaaaacaat ttttaatcac agtaaagaaa ggttcgtttt 536040 ttcaaaatta gacaatggtg ccatgaaatt tttctagcat tttcctaata aaatcagatg 536100 atctgaaata cataaacctg gataaatctg atgaacttag ataaacaaag ctattcaata 536160 cacatgttaa ttatgggcca atacgtaaaa gaaaagtagt ttcgtagtct ttcaatttca 536220 catggtcttc actatgcaag ccccaatcat ggaggctttt tttttttttt ttttttttga 536280 gacggtctcg ctctgtcgcc caagctggag tgcagcagca ctcagcttag tgcaagctcc 536340 gcctcccggg ttcatgccat tctctggcct cagcctccgg agtagttggg actacaggcg 536400 cctgcgtgga ggcctttttt atatcactca ttggaaaatt ggggcccggt gtggtagttc 536460 acacctgtaa tcccagcact ttggggaggc tgaggcaggc agatcacttg agctcaggag 536520 ttcaagacca gcctgggcaa gatggagaaa ccccatctct acaaaaacac aaaaaataag 536580 ctgggtgtgg tagcatgtgc ctatagtctc agctacttga gagggtgatg catggggatg 536640 gtttgagtct tcagcctggg aggtggaggt tgcagtgagc cgagacagaa ccactacact 536700 ccagcctggg cctcagagcc agatcctgcc tccctccacc aaaaaataaa agattaaaaa 536760 aaaggaaaat tggaatcttt ggaatgagta ctactaaaaa ttgatttctt cccttttaaa 536820 tgactaagga aaaaaatttt aattgaattt aaatcatttt actacatgtt tagttgctac 536880 tgtgaaacaa tgaaaacatc ttaagaatta agtctgaaaa aaatctgtaa tttccaatag 536940 aaaagtagag cttagaaatc agaaatcaaa ttatacagta tataagtatt ttaacctgtt 537000 tataagaatt ttaaaatctt tgaaaatgtc attgtcactt taagtttaaa aataaggagc 537060 tttaacatgt ttccttgatc actaggagta tgaattaagc ttaggacatt ttctgaatgc 537120 aaaatggttt gaaaattaaa caattcatat ttgagtttca tggtttctat ctaaacattt 537180 tttttacagg ccaagttaca acatccatgg aaatgctttt agttataagt atggtattaa 537240 caggatcaag aacagctgac aaataattac aattaataaa tttgttcaag ctgacaatgg 537300 tgtgtctaaa aaattaatga atttaataaa atgtcacaaa tgcccttcct tggaaccaag 537360 agcaacaagc tataagttaa tcagaatata actctgaagt tccattttag gcacattttc 537420 tcatgttcca gggagaaaag caccataacc tcctggtaaa atactccttt ttgatacttc 537480 tactgccatc acttcagtta tcttactgga actgcttaat ctatgttttt tcttacaagt 537540 atttctgcat ataatgcaag tatgctttat agctaaggtt taacatttct agatacatca 537600 aaagctagag ctaaggttta ccaaatttaa gaactttatg aagtttataa ttttctatct 537660 caaaaagggc gtcgtcttat gtatctctga tttacttaga acaaactaca tacaaatggc 537720 atagcttttt agttattaat aaaacactag ctagattata gataagggat gcgtgtgtgt 537780 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgact aagaacagta acagaaaggt 537840 caactcaatt agaatcaaca ggctataaca gctcaaatct caaagctgaa gggaaatgac 537900 atacattatt ctatgcacac tcctcacaat tctgatggta ccttcagtgg aaaccttttc 537960 ctgtaattgt catgtactca attttaaacg taagcaagct cagttactaa gtggttatat 538020 ttacagtaga aactgaacca gttcagaatt atgaagttaa gtagactacc caaaagactg 538080 catcttttcc ctgttctact ttatcacaaa agggaaaaaa ctaaaattct gatccttcac 538140 tttcaaattt ccaaatccca tcagcctttc ccaaactgtg ttcaataaca actcttctgt 538200 tagggcagaa aaagagttct ggagttcaaa aagtttgggg gaaacactac ctatattaag 538260 ccccaagaaa tcttatagca aataaaccta attaatgtga tatcagctag tgtttctgaa 538320 ctttgagcat gacatacttg tgagacagtc tctcaatact cttcaaacca ttgttctttg 538380 aagttcacag gtcaggaaaa ccgtgagttt gatgatggtt ttagacaaca aaaagcaaag 538440 aaatccctcc aactgttcca atataccatt ctaaagtgct ttcaattcag tttaccaaag 538500 agataatttc cttcattaga atattccttc taagaaataa aagaatttga ataaattagt 538560 gatacaaatc agttcctaaa acctacaaat tcagtcatga tgtgtgattc tgggtaatcc 538620 ataccaaatc cttcttttgc tgctcttcat agctgaaaat atttacaaag taagataaac 538680 aaataactaa ctcaaaagat gatacgacac cataatcaca ttactaatgt atttaccaat 538740 atctggattg aagatttcct ccacaaccag ctgaaaaaat tctttggaaa cacctccctc 538800 atcaactcct tgttctcctt caaattccac atacaactgc ttcttcaagt ctgcaggatt 538860 ttccatagcg atcatctcta gctagtgatt gaaaagataa acatgaaaag aagatgattg 538920 ctagtatcag gaaaaaaaca aaataaaaac aaggagtagg attaggaaac aaatacaaat 538980 ttttgacttt ttgtatgtaa atggaaacag aaagcaaact gataaaaagc cagtgaagac 539040 aaagattcag tcttaaagat aatcaaaaag acagacacaa aacagacact agcatagtaa 539100 aaagctaact ttactgattt gttatgaaat taacatacaa ttaattaaga ttttattact 539160 tgtgtgttaa gtctggacta cacaggacat ggaaaagcag ctaaatcatt tcagcaaaaa 539220 caatggagta gaggtctaac ctcaaaattg ttcattagta gtcctttatt agaatagaaa 539280 ctcaagggtt aagtcttagt atctactaag tcataagtaa aatatttcaa ttaagaaaaa 539340 tacactgaat actaaagcag tttatggtct ctcacagtaa gacttagtat aaattaccac 539400 cttttaatgg actagaaccc atcttatatc cacatttcct taaaaacagg tgagacataa 539460 ccttactcat gtccttactc tttttttttt tttttttgac atgaaatctc actctgtcgc 539520 ctaggctgga gtgcagtggc gcgatctcag ctcactgcaa cctccgcctc ctgggttcaa 539580 gcaattctcc tgcctcagcc tcctgagtag ctgggattac aggcaggcgc cactacgcct 539640 ggctaaattt tttattttta gtagagatgg ggtttcacta cgtttgccag gatggtcttg 539700 aactcctgac ctcatgatcc gcccacctca gcctctcaaa gtgctgggat tacaggcgtg 539760 agcaactgca cccagccctt attcttaaat tgtaagttaa caaactttag tgtctagcat 539820 tttctcaact ataaatcttt taccaaatat ttttgtgtac ctatagaatt atgaatatac 539880 agtaacctca ttgagattaa tcataaaatc aacactagat tccaatatta actgtttata 539940 ctgcattttg tttgttttac tttatgtatc taaaatttgc taacagtatg actgtatcca 540000 gtacatggat ggatactgta tctagtacat ggatggatac tgtatccagt atccatcata 540060 tctcctaact tgccttcaaa catctgttgg ctggttaaaa aaatttaatc ttggagatga 540120 aaatttacca aaacaggata ttaaatgttt tcaggttatt ccaactattt caaacagaat 540180 tttaaaaatg gttttgaaaa atgcaataat cactgaaaca actgtaacac agcactatag 540240 tagttaaagt aataatactc atttggacaa tctagtctgt ctacaaaaaa taaaatctca 540300 taaattaacg catcaggtca ggttgcccga gagcattgtt ttttcaaact tgtcacctgc 540360 aactcattag tgggtagtct aatccattta gtggtttgca atcagcaatg ggaaaatcag 540420 aatgcattcc acatagtaat ggaacctact gttttgtgaa acttttgttt caattagatg 540480 tacagatgga taagcatgta ctgggatgct atgtaaaata ctagggattg cagtcaaaga 540540 gtttgacaaa actagctgaa attatcttct gggtatcttc aactttaggg tcctattctg 540600 tgaatttagt ctttagcttt aaataatgtc tgttgttgtt caacaccgat ctctaatatt 540660 tacaaaatca tttttaggcc acacagttta cttttagaca atgttttgtt atggaaagac 540720 caagagtcag tcagaattca ccttactagt cccaactctc acttaccata acttttaacc 540780 tttaaacttt agcacgcgat tcaattaagc ctcagtttcc tcaacatact gtaagttgtg 540840 aaggcttatt aagaatatat gagaacgagt gttacctttt aaaatagttt tgctctctga 540900 acaacagatt tgcaattttg tgtccccaaa ggaacttgat atagactagt tccaagatct 540960 agagtcaaac aaatgtagat gtgaaaataa ccttggggaa aaaaatagtt tcagttggaa 541020 acctgtttca agctacggag tatacagaat tctgaggaga ctaaaattag aattaacatc 541080 ttagctcaaa tgtgggacca ggccaacatt ccatattgcc atgtaatcca ttctgagttt 541140 ccttatgcca gttcccaact ggctaggtgt taaagatgta agtcagtgtt tatatttacc 541200 tttacatcca aaggtatact tgcttttatc aaatataatg tattccaaag tggggaaaaa 541260 aaaggttatc tggtatttag actgtgcatt ctacagcttt tccccactaa cattcataga 541320 tgagagctga ctccttatca atgtaaaacc ttttaaagga tgtggtggtg aatttctaca 541380 ggattgagag gccctgtgtt ctatctagtc ttagctctac ctaagacatg tcaaatgata 541440 actgaagcaa atttatcttt attctccata aaatattaca tgtctgtcca cttccactga 541500 tctctattct atgctcccca ccttggtgcc aaaagaatgt aatgcaatgc aatatgttct 541560 attgtaaatg caaacataca actttacctc tcttatttca tctgtaaaat aaccataata 541620 atatagtaat aaattaatgt atgaactgct tagattaatt ccctgcataa agttagtgct 541680 taaaagtact agctgttgtt gctgttattt tattggttct aaaatatttt ctgaaaacct 541740 accatagcat tatagaacaa aaatattcca tgaatacagc aacaataata tatagcactt 541800 ttgtagcatt tcacacatag caactaattt aatcttcaca acacccttat gaggaaggaa 541860 acattaactc cactttacag ataaggaccc caagatactg aaaggtgaaa taacttcaag 541920 tcacagtaag tcacagtaag ttgtggaaca gagatactaa tccaggaaac aagctcttaa 541980 ctactatgct ttactcactc tcttcaatga cgaccaaaaa tttttttttt aggattatga 542040 gtgattttta ttttccttat tcttttccat atttttccat tttttacaac aaatacattt 542100 ttcagagtca gaatgtgttc aaatataaat atgtaaaaag aataatttga aaagtagttg 542160 gtaactgaat tctgtaggca aaaattttgt tattacctat tttagattac cattctggta 542220 cacataagtg atttcataaa atactgtacc acttaagaat aaaggctggg cgccgtggct 542280 cacacctgta atcccaccac tttgggaggc caatgcaggc agattgcctg agcccagcag 542340 tttgagatca gcctgggcaa catgatgaaa ccttgtttct acaaaaaact aataaataaa 542400 taaataaata aataaataaa taaataaaaa atagtggggg gtggtggcat gcgcctgtca 542460 tcccagctac ttgggaggct gaggtgggag gtcaaggctg cagtcagtag agatcgtgcc 542520 actgtactcc aggcctgggt gacagagtta agaccctgtc tcaaaaatta aaataaataa 542580 aatagtaaaa acagaataca taaatagcct ttaaaactat tttattttaa attattaaca 542640 cataaaattt agcaataacc attttgataa aggccattat tgcataaaca gctgtactga 542700 taattctttt tcttaaaaat aacctccatc aattgttcgg tcaatttaaa aaagatttaa 542760 caaataaact gtaaaggtgt attctttaca taatagctat attatttaaa attgtatgtt 542820 gttgtttaaa cccaaacctc accataaaac tgtatttttt aagtcagaag ttgttttaaa 542880 tgcattagga tatttgaaat ttggaggact atgtctaaac attctgaaaa ggagaacgtg 542940 catgcatgcc tgaatttatt tacaatacac acgtggattt ttagggtttt ttttgtttgt 543000 tttttttttt tttttgagac ggagtctcgc tctgtcgccc aggctggagt gcagtggcgc 543060 aatcttggcg cactgcaagc cccgcctccc aggttcatgc cattctcctg cctcagcctc 543120 ccgagtagct gggactacag gcgcctgcca ccgcgcctgg ctattttttt ttgtattttt 543180 tagtagagat ggggtttcac tgtgttagcc aggatggttt cggtctcctg accttgtgat 543240 ctgcccgcct tggcctccca aagtgctggg attacaggtg tgagccaccg cgccaggcca 543300 atttttaggt atatttaaaa gtacagtgta tgttgtattt atttaacatg gagactagca 543360 acagacagag attactgggg aaaaataaac aaaaatatcc tggatataat catatctacc 543420 tcttcactgc gtaacttcct cttctttaag actcttgatt tcatcaattg ctggataaaa 543480 tgatttttaa tttctgaact ttttaattgg ccatgatgat gaaatcctag ggagttcatt 543540 ttttaaaaaa aaaatctgac ctgatatcaa agcatttgca gaatacctag caggatgaca 543600 tcttaatatc aaaatatgat attactagac ttacaggaat caaaaggaaa accttatcac 543660 ttaaaatctt atagttttct gagctattac atcaaatcaa ttcataattt tttaaaaaaa 543720 ttccttaata ccatgaatat ttaagtagaa gcaataatca gataaaagag acctctaata 543780 cttaagaatg cctgggattt ctaagaaagg ctagcttcaa ggccgggcgt ggtggctcat 543840 gcctgtaatc ccggcactct gggaggccga ggcgggcgga tcacgaggtc aggagattga 543900 gaccatcctg gctaacacgg tgaaccccat ctctactaaa aatacaaaaa aattagctgg 543960 gcatggtggc aggcgcctgt agtcccagct actcgggagg ctgaggcagg agaatggcat 544020 gaacctggga ggcggggctt gcagtgagcc aagattgcgc cactgcactc cagcctgggt 544080 gacagagcaa gactccgtct aaaaaaaaaa aaaaaaaaag aggaaaaaga aagaaaggct 544140 agcttcaact acttcagtca acttgaggct taaactattg cttgagattt ccagattatc 544200 caaattaatt ttttcatgtt cacgataaac acatgaagaa aagtctgtta tatctcaaat 544260 gtagtttaaa tgtttgggta acaccaaatc acataatcac gttcgtccat gagacctgga 544320 atcctgactt ctatttccaa ttctgccatt aatttatgta ggctggaatc tcttttagat 544380 ttcattttcc tcacatgtaa tactaagttt gatgtttcat tgtcttaaat tattatataa 544440 tgctgaggat ctatgtatat ataggcttca ttctctcatt cagtttctga gaaattactt 544500 tgagggcata aaccaagcat atttcttggt ttcatttttg atttcaatta gaataaatca 544560 caagaaagaa caatggaaat tacatgttaa ccacaatata gtgtatgtgt aagacaaaat 544620 taaacatacc tagtgcagca cagaataatc tcatttttaa agctctgtga gtcaatgaat 544680 aaataaaaga attacgttca tgtttcacta gtaagagtgt tcaccaatgc tggaagctgg 544740 gagctgaaaa tgctggaagc tgggttagac taggctatta gaaaccagat aaaaagggcc 544800 agtgactttt agaggggatt ttgcagaacc tcctggtagt ggggcttttt atctgtgcca 544860 atcaccttta tctgtgctaa ttcctatttt tgaacttccc tattcaattc cacatctcag 544920 ccattccttt tggtttttag atatttatgt gaaatgctag aactccctga ctaattggaa 544980 ccaagtttca catcatcatc atcctctatt ccaagcttgc tgtccccatg atcctcttaa 545040 aaatctgagt ttccaaaaca cataaacata cttgtatatc aaaatggcct ttctctttct 545100 ctctatatat gcacacatac acacataaac acacatgcac acacaccccc acctgagctg 545160 aaccaaaggc catcttccca aatattggag tctggcttta tcaaaatatt tgtggagtat 545220 taccagaagt tcagattcat aggctctaca atacagcttc taatctaaac ctctagaggt 545280 tagggccctg gattttattt atttatttat ttattttttt taaacaattt tcccattcag 545340 atgtgaaggc agtttgaggg acctcatgat ggcaatacta tattcttcca taaacttata 545400 acctctatct tctcctttaa gaagtaattt aaaaaatctt aatacatact atcattggaa 545460 gtgcttcatc taagaaaaat gagaaattat ctacttgtaa aagaacacac aaatgggtat 545520 atttacatat ttgtaaatat gtaaatattt acatatttgt aaatatgtaa atatttacat 545580 atttgtaaat atgtaaatat ttgcatattt gtaaatatgt aaatatttac atatttaaat 545640 taaattaatt tacatattaa attaaattac atatttatat taaaaatgta aatttgtaaa 545700 tatggtttta catatttgta aaaacctcat cacattagga atgtcattca aatgaaaggt 545760 gaagtctaag ctcatgttta tcactgtact gttttctaag gaacaataac gaaaaaatac 545820 tgaaaataag tcctagggga actatggcag taagttaaac gggtagggtg ggggtgttct 545880 taagcagttc taaggtattt gtgaagagac aacttatatt ctattgattc taaaattcac 545940 ttttttcaca ttatctctga aatcagatta caccatacaa atgatagcat cttacaatga 546000 attgctggta tttttctgtc ttagcagtaa taaaatgata gtgtttccta caatcagaga 546060 ttagtgaaaa tactatcaac atgaattctt ctcttgtcat caaagacaat ttctctaaaa 546120 acctcaggaa aaaagctgct agtctggttt gaatttcaca atatataaaa gcaatgaata 546180 tatttttctt ttttaaaaaa atccacaatt attaattcaa gttaccactc ctcaacagaa 546240 aacatacaag agtctcatat atgaagtcac tattttctgg gcttgatttc taaactaagg 546300 agtggataac tctaaggttt cttttagctc ttaaagccta ggatcccata attttattta 546360 tcaatattaa gcttaccaca aagtttctca tttcttcttt tccacccaac cctgctatac 546420 aattccaaaa ttagcaagtc ataaaaaagt ggccactagt ttgttcactg tgatatataa 546480 gaatgaggct taaaaagcag agatccttgg gaaataagat cttgaaaaat tcatcacttt 546540 tgagctttca tatgagagaa taatcttaaa ccactttcta ttatagaact tctactatgt 546600 gttactaaaa tatgtggctt tatcataatc atcacctgct gtgaatactt acttcaaaaa 546660 attacacagg ttatcaattt tacttataag acctatttcg atgctggttt ttctagtctt 546720 ttcacattct gttatttttt taaaaaaaag aaaaggaaga aaaagcaagg gagaaagaaa 546780 gttaagagta aaatctgctt agtgtgagca ttcagagccc ctaaggaagc ttctctgtaa 546840 gcatcatctc tttctatttt cacagtttat taaactgcct aacacacatg atttctgaag 546900 tgaactgctt ttgtgggctg gcaatattca agtacatata ctatctagtg aatcctgatt 546960 tatgataggc cacactatat tatctaattt tgatataatt aagcagaact tgctaaaaac 547020 aagttaccat aattaaagag ctcacagtta attttacact aacacctaag gctttaaaag 547080 cagttgtttc cttaaaattc tagaatagaa tttaaaatat agaataaagt atataccaag 547140 tacttaaact tttgttttta gtcttgcttt actagagaaa aaaatggggg actgaggaaa 547200 ataagactga gtagacttct gagcgaaaga cagataagga aggtagacaa ttttttgaac 547260 cctggaatga ttcttacagt gtaatttcat tgccttttaa aggctagaca tagcttttga 547320 tgaagacagc tgaagggatc tcacctcaag aagccaaaca taaagtatgt agctttggca 547380 tttgcagttc tgctccaaca atggatagtc atagacagac ctcaacatac ctttcataaa 547440 acatcactca cattcttata aaatacccta tcattctgct aaactatgta aagtaaggtg 547500 ctggctgcct tatgatcagt cattaagtgt attaattatt catgtgtctc aaaactatgt 547560 aagtgaaata aaaagggtac cagaaagcaa gcaataataa tgacttcagg cagttaaagc 547620 ccccttttgt ctctgctaga aaaccacctg agttgcttaa ataatgcaga atctttctcc 547680 aacactataa acatatctga cattaaaaaa aaaaaacaaa ccagtaacaa aaaaaaaaaa 547740 aacacacaaa atctctgcaa tttttaattt ctgagatgtc aaataacttt ttccaccggg 547800 ctacagcttt atgaattctc gaatttagac aattctaaaa ctaaaattta gacattctaa 547860 aactaaaata cattttaaag taaaaatcac atttcctagt tgtctgtgtc agacaacttt 547920 actagtatac tatagtatta ttaactacct taatttttgt tgacattaaa ttttacttga 547980 agatgataaa aaagtagcag caatgacagg gatagctaat actagaaata caataaagct 548040 ctgcgataat gcacctgaga caaatgtaaa ttttggtgaa atgtgactga cgactgcttt 548100 ctgtcttctg gccactctta tattcttaaa cagatacact aaaattatct tgtggaggaa 548160 agaaaaggaa caaatggcaa ccccatctgg aaaaccagga agttaggatg agtacctgag 548220 tttccagtat ttccctgctc aatctccctg gacttgatgt tacaggcacc actaatcccc 548280 agatttttgg aatagctgct gttttccaga agttccaaga cccagagttg tctctatgaa 548340 tttttaagtg ggaagaaact accacagcca ggcagtgccg tccacacagg gatattctaa 548400 gtggcccagc aggactcaac tcttactggc aacaggcact gatctgccat ggtcacttca 548460 tcaagtccac aataatgcaa ctctgaattt tacacgatgg aattttttgg acactaccta 548520 taattttatg gtatggtttt actgtaccat tactcccagt tcaagactgc acatccacac 548580 ttattattgg gtatctccac atttctcttg ttctggtctt tgtccaacac tctattctct 548640 tctgaatgaa agaaactttg gatttagttt tcaagattta gaaaacccat tctttttcaa 548700 agatagcatg accattatat aatacaaccg atactttgta gaacacatct ataaacttgc 548760 acaggaacaa caaaagtata atacttatat aagatcagaa atgtccatgt gttcctatgc 548820 tatatggtat catttttttc agtcactttt aaaatgaatt cactgaactg tatcatgata 548880 tccccattat taggttttta atctagcagc ccaacttacc cggacaagtg catcatctat 548940 gatatggtca cgtctaactt tgagtctcaa atatggattc aactgctgtc cttgaactaa 549000 gctgtagaga acagtgattc ttcgttcact gtacatgcga attctattgt cataatataa 549060 tcccaaattc tttgtgacag cattcaatat aaagggacat gtcataaaag agaatttgtt 549120 ctctgtttct actttgaaaa aagtataatc tttatccatt tctagaacct cattcagtgg 549180 ttcattaata aactcttcaa aagggataag tggttttcga caatccaggg ttttaacacc 549240 aagttcagtt tccagggggt ccactcgagg acctttcttg tttcttcttt cttctcccaa 549300 aagttcctga agtgtcagct cgctggactc agggatgggc tcttcatcat cttcttcatt 549360 gtgatttgtg tccacttccc ctcccactac atttgcatag taaaccattt tcaagcactt 549420 cgaagcagca acaatggcat catcatcatt cactagattt cgactgttaa attcattgct 549480 tatgacttta taagtaataa gttgctgaaa tgtctccatc attctccgaa tctggtctgc 549540 attgtattta gaccacagtc tgatcagttt tccttgggct gcaaggggta gcttgctcat 549600 cgctttgcaa aataatggca aagccatttc cagatattca ggactgtgga gatttctatt 549660 ctccattacg ataatgaaca aattcagata attaggatct cgagagtata cattgtgata 549720 cgtcaagtca cattccacgt taggtgacaa atatacaagt gcattgagaa aggcagtttc 549780 aattttttca ttagagagca atctggtgta gacccttcta atggcatcaa tatccacaga 549840 cacatcatca gggcctaatt tttgcaaatt gttgtctccc tgtgagctat cacctatcct 549900 tgaggaagat gcttctgagt cttcttccat agcagcagca gaacatgcag ctttttcctt 549960 ttcatcttca tctttgtctt catcttttgc ttgaagagat ttcagttctt ccttggtgtg 550020 ttgtttaact ttccggaagc tctgtaccaa tgcctcagca ctagaaaaaa ctcttccaat 550080 aacacggatt aaaggggaat aatcctctct ttctctacat aattcaagaa tttcatatac 550140 cttctcttct gttaagtaag tcacatctag aaaatcagag gaaaaaagag aacatttatt 550200 ttcataatat gtatgtttac tctgttgcaa aaagttctaa aagtaaaaca gccaaacatt 550260 ctaggctcaa tatcatttat gatatacaac tcttaaagta tctaatactt agattcagca 550320 aacaaaattt aatgcttacc tatttttttc aatgaactac ctacctatac caatgacctc 550380 acccatgctt ttacattctt tcaacaatgt ataactctta ataagatcat gagtttaaac 550440 tttctttata atcaagatat ctattaatgt atagctttaa ttataaatat gaaccaatat 550500 gtcatgtact gattaatcat aatacagctc ttaaaacctc actgtagaac acacagaaat 550560 actactaatc tgtgagtttt cttgtttcag tactctgttc tccaaagact aagaaggcaa 550620 ggtcttaaaa aaaggctcct tcagcatcta tgtatgtatt aaaatcaaac tggttcattt 550680 tgggtcttcc tagtttgttc cagggtagtc attctgtgag tgattgagaa gaatatacca 550740 tttctcatcg gctcttaagt agaaactgct ttccacagcc aggaatcagg ttagactaaa 550800 tctcatagag tgacagaaaa tagtttttga gcaatgaaaa caaacagtgc aaagaagtaa 550860 acttatgagc tggcaagcag tgcagagact atgtagtcat caaaatctat ttcctctttt 550920 cctgggcaca gagttggacc acatttccca actttttgag ataagtgtta ttttcaggcc 550980 aaggctttct cccttctggc taataggatg aaagatattt catttcacag gtaaaaacaa 551040 atgatatatt ttgtgtactg accaacataa tactgagaat agtcttaatt ctccctttta 551100 tcaataaagt gacatacttg tcatcatcag attaactact tgagaggtta attttagagg 551160 cacacagaca atcctacctc cattgcgcca aatataccct tatacatgta gtgtacaaca 551220 tgtagaattt ttaatgactc ccacctctgc tataatatat gtttcacaat gaaagacaat 551280 ataaaatgta agtgatcatt gaatggtctc caaaaattga agcacaaaaa taccaaattt 551340 tatcatacta aggatctgat ctgtggccca gctacaagag taccaacact tacagtttct 551400 tttatgggcc ttaactcttt aagaactaat tctcaggttt gttctattaa gaatatataa 551460 gcatcttttg ctaaacatca gtaacctctt ccccaaaagc ataaaaccac tggaaaccta 551520 tttctcatta ttttcattga aaatttttaa aataccttct tacaagacaa tgcaaaactc 551580 ctaatttcct aaaatgtaac ataacagaaa atactactat cctattagga catgaaacac 551640 tttgcttcct gagcaagtca taaggttaac aaagacttgc tttgcatgca gtaatatggc 551700 ctgtcctagg gatcaccatt ctagactcac atgtcctttg ttgatatgtc atgctttcgg 551760 aacatcttca agtgattctg acagtctact aatcctatat agaatgtacc tatacttttt 551820 ccaaggagtg ttttttgttg ttgttttttg acatggagtc tcactctgtt gccaggttgg 551880 aatgcagtgg caccatttcg gctcactgca acttctgcct cccgggttca aacgattctc 551940 ctacctcagc ctcccaagta gctgggacta cagatgcacg ccaccacaac tggctaattt 552000 ttttgtattt ttagtagaga gggggtttca ccacgttggc caggttggtc tcgatctctt 552060 gacgtcgtga ttcgcccgcc tcagcctccc aaagtgctgg gattacaggc gtgagccact 552120 gtgcctggcc tgtagtgttt aatatgttaa actgaatttt tcaggtatat agataaaaat 552180 tagtcaaaaa acactgtaat tagatatgaa cattcaaaaa gtttggttta ttgatacagg 552240 tgttctactg agaaagacat ttttataaga tttcttgtga taaatgtgtc cctgaaaata 552300 ctcaatcttt taaattttgc acttaaaaac ctcctacgca aaaacagttt ggtgcagact 552360 acttaatact tatgcaactt tgtaattagt gttaacaaac ataattaata atcaaaataa 552420 gagtactagt gtacagaaag catctctaat ttccaatata caatagtaac tatagaacaa 552480 tgcaaaaaca aaaacaaaaa aaccagtaac gaacagggaa cagtaacagt agcatattag 552540 aaaacaggga taaggaaagg tcacaactgc tataatgcag acttgagcaa aaagaggagg 552600 gggcataaag actggataaa gccacacaat aagcacctct aagatggagc acgtggccaa 552660 aagagcagat gagcacattc ctcatgtacc acatcccccg cagctggctg cattccactg 552720 tgccagcact ctacattcag ttactggtac tctctggtgc acacttactg gagaactgtg 552780 tacaataaag tcaatgcagc ttccacatta tactgacaca ctatatatac agacaacatt 552840 tacctatttt cccatagtgt gtgaactaat tcatgaaaca gaattataca ctctgaagca 552900 acaaagttgt gtaaagtgac gaaaataatt ttattgtgga aacagagtag aggttataac 552960 acaatgccac ttcactaatt ctttcaaact tgattcaaat gatgttagtg aaagttttag 553020 aggcaaatgc ctctaaaatt ctctgacttg tatgtcataa aaaaaaagct ttctctctta 553080 aaatacaatt gcctctgggt gtgtgtaggg gtgagagtgg aggggcgcta agccctggta 553140 gtcattcaaa aatttgatta ctttgttact aattaccttc actgaagaaa ataacttgga 553200 gttttagtat tagcgacaag gtaatcgaat tctgaatttt ggacgtagga ccatttagaa 553260 aacaaaagac ctgagtgaag actgtcattg gtaggtcatg atccttggca gcatgactgt 553320 accaaatgtc cggaaggaga gtgagaagca tatatctgaa ggaaacgtag aattctcaca 553380 taactatcac aaaattttgt cttgccttca aaaatggaaa aaacccactg tttcctcttt 553440 ctgcttcttt catcacatca tcctgaggtt ccagaactca tgccagatac ttagtccagt 553500 tattctataa cttaaataga tgttgtggcc tagttttgga gattcactac cacttaatac 553560 atttttccta agaattttaa aaagttcaaa tcaatctatt aacaaatgaa cttttggcat 553620 atgatctgct tctaattagc aatgattaga cctgtaaaat gtagttatta ttcctgtccg 553680 ttaccacaat aaaaaattgg ttctacgata tcaaaatgtc tttatgtcac agaagaaaaa 553740 acaaataaaa actaatacat ttaaatctcc cacatggttt tcaggcaaca attctcaatt 553800 gaaaataaaa catcttacct ttaaaatcaa ttctagcgcc tttcttgttc atttttatct 553860 cagagcagga gttgttgggg gcacctttcg agttctcaag gtaagctgag cttgctcctt 553920 tcttggaggg atgaggatca cagagttttg cattaatctt ataaagctcg agggctttaa 553980 tagctgctgc attattatcc atacgaagaa aagttggaca ggaagcacaa aactcattcg 554040 tgcaggcttc atttccacag ccctcagtta actggtggta gtagcgttct attagatgct 554100 ttgcagctgc tcgcttcctg taccaaacat tcaaacaata agcacagtga ttagtacagc 554160 tctcaagtac aaagctcaac atatcatcaa ggcaaaagtt agtcaagcac tgaagtgatt 554220 aacctgtgta tgaagatgag aagtagaaaa tggagatgca ctatttacca caactcctga 554280 ctagtgaaat agttaataaa tattttctag gatattatga taaagaatgt caatgcttac 554340 tgactgtatt aacagagtat acattccttt ggtttaaaag gggggagggg ggcttgtctg 554400 atggtatatg tgcttaagtt gtttagtaca acagctgaaa aatcacaagg tttacagcta 554460 agagttgtag gattctatca ttttaaaaat tagcattagg aaaatgagtc tatttaaagc 554520 atcaatccgg ttttctttta cataatcagt atttcatttt taacagcttg taaacatttg 554580 acttatagtt aacacagaat atctatctgg aataaaaact atttttccca attatcaaca 554640 acatgggaga cttaaaaata aatttgtaag tggaatatcc aaagatagtg ttacactgaa 554700 agaaagcggc tgcagcctga gtgaggcaga tcatgactgt aatcaatccc ataactgtgg 554760 gaggctgagg caggccgact acttgagccc aggaggtcaa caccagcctg ggcaacatag 554820 tgaggctact ctctacaaac ttttttaaaa aaaattagcc aagtgtggtg gcatgcacct 554880 gtagtcccag ctacttggga ggctgaggat cacttgagcc tgagagtcaa ggctgccata 554940 agctgaaatt gcaccactgc actccagcct gggcaacaga gctagacttt gtctcaaaaa 555000 caaacaaaca aacaaaaacc aaaaagaaaa agaaaaagag gctccaaagt gtagaatctt 555060 aaatctaaaa cttgtcacta aacctcctca ttagttccac gtcacaagat ggaatatttt 555120 aagttccatc acgtgaaatc ttatattcct tttactctgt caacttaaag tacacagatt 555180 aatgtcctat tatggctgtt tcaggagagc taccaaaact gagggaggaa ttatgtgacc 555240 atgtaagaag ttagatgaca ttatattcaa cactaaagag tctatgcttc tactaactga 555300 taaaattacc ataatttcag tagaataaac tactggatcc aaagaaacat aagtcatagc 555360 cattcctttt ggtcccaaat tcacaagcat ggaaataaca actacaaaga atcaaaatta 555420 taagaaaaat agttcagctg attttcaaaa cattcacaga attatctaac atgtaggact 555480 agatgaccaa tgccagagtt tacatcttgc taatcatgag aaactcaaca attaacaagg 555540 cagcaagtaa gtgaagaaac acacgagatc caattttgtc tcaacagaag aactttcact 555600 ctctgtccag gtaggtgaca aaaagtgata attcacacac attcaattca ttctggtgct 555660 tatttttcaa atgttccatg caaatttacc actcactgca tgcaaacaga gaaaaaagaa 555720 aacccacaaa gcacatgtaa aaattgcata aacatgactt aaagacattt tgctatctat 555780 gaagctataa accccacctg aaaattaaaa actgttatca cagatttagc actatgcaaa 555840 atatgaaagt gaaaacatgt aaaaataaaa tggaaatgca gaatctagaa aatttaaaat 555900 atatattgct acccttcagt aaagaaaggg agataatgtc atgttctccc aaactacagt 555960 gacttccctg gtgaaaatgt aagtaggtat ttcctttctg gaggaaaaca gtgaacatgt 556020 atcgaaagtc ttaaaaacac gaataccgtg tgaatgagat cctacttgtg gaaaataatt 556080 tgacaatttt acaaaaatgc attgtttcta tatctgaaaa aaacatgtct aataaaagat 556140 tacttaaatg aactgataat aggtcacaca ataaaataaa aactatcaag atttgaattc 556200 gacaaagaac tgcctagtct tcctgatata tcactaactg acaaaagtca gttaaaaagt 556260 agcaggtgta ggatgaaccc attgttattt caaagcatta atagcatttt ctctggatga 556320 tgtgattaag tgagttttaa aacttcttcc atcttttgat ttcttattta ttctttccat 556380 agtaaggatg ctacttgcat attaaaaatt aataactata aggggaaaac aatagcagtt 556440 ataaaacttc atatacatga tttgaatggc cccgagattt actaaattgt ctctgatttt 556500 taaaaaaatt acaaaagtca aaataccaaa atagatattt ttaatgtgag cttttatact 556560 aaaataacct ccccaaaact tgtcagatac atagtacttc tttatatact acataggagg 556620 agagtgatca gcacaaacag aacgagactg aaaaatcaga agatctgcat taagtgtcat 556680 ccttctgtcc ctaagcagct gtaggatcct agggaaacaa ttgtctgggc ctcagttttc 556740 ccagctttat gagtcccttc agttctaatt ttaaagttat tttatgtaat agggaggtga 556800 gcaagaaact agtatttgct ggatgcctga taacttatta cacacactgc ggggcacttt 556860 gacatgggtt atctcatttg aataccatga cattgaggat tatcttcagt ccacagccaa 556920 agagagaaat agaactggag tcaaatcacg aaaccaagat ctcaaagaaa gtacagaacc 556980 aagacaagaa taggagtcca ggagtctttc agcttcagag tctaagtcat tttgactata 557040 ttgttttgca gaaggtgatt catttcaaaa taattatttt ttaacatgag taatactgaa 557100 gaattctatg gaaaaaaatc tcataactaa tgtgcaactg ggaaaaaaat ctgaagaatc 557160 ataacgtgaa cctcacattt atgcatctat ctggtaccac aaaggcagac caagtttctt 557220 gaggaaatgg aaccactata ttctgcaaag ttaatttctc tctaatttgt tgaggaccta 557280 tgtgctatgc attttataga cattcccact ttagagggga ataaacctta acagttaaga 557340 gctcgcattc tgaggccaga tgcccaagtt cacataatgg ctctacctct taattaacta 557400 tgtgaccctg aatgaattac ttgatctttc tggacgtaag tttcctcgta atttaaatgg 557460 tagtatctac gagcattatc atggtgagag tattattctt cttcacatta ccaattgtga 557520 gaaaattaaa tgtgttaata tatataaagt gcttagaaca ttgcctggca catactaagc 557580 actatgaaag tgttagctac tactattatt gttgtaattg ttactatcac cctcacaagt 557640 gtatgagtta gcactataaa ccttcattct gctgatgctc agagaaatta cataagtcat 557700 acatctaata agagatttga actcagctac taaacttgag cttttaataa ctattaagag 557760 gaggatctga aagtagccct ctatatttga tctgcctttc tgtgccaagt ttaacaaata 557820 gcagctacac tgatgagaca ggactaaagg aagccatgcc agaacctcca agttaatggt 557880 ggaatcaact atattaagca ttcttctttt ttcctcactc caatgacacc ttaatttatc 557940 tgacctcatc tgcatcacta tctaatttag gatatgtaaa aggcatacaa aatttagagc 558000 acataaaagg gcctctacgt tggaaaagta tacactaata acgacttttt ggtatagttc 558060 ctgcgcaagg gaaatccttg taccatatgg gtcaccaaat catagctcgt aagtcaaatc 558120 gagtccacca cctgtttatg tctctcaagc ttagaatatt ttacattttt aaatggctgg 558180 aaaaagtttg aaaaataata atagtttgta acgtgaaaat tataagaaat tcaagttcca 558240 gtatccatca agtgtactgg aacataccca agttcattga tttataaata tactatatat 558300 gataatgctt tggctctgtg tccccaccca aatctcatct tgaattgtac tcccataatt 558360 ctcatgtgtt gtaggagtga ccccctggga gataatctga atcatggggg cagtttccca 558420 catgctgttc ttgtggtagt aagtctcacg agatctgatg gttttatcag gggtttccgc 558480 ttttgcatcc ttctcatttt ctcttgtcac tgccatgcaa gaagtgtctt tcacctttcg 558540 ccatgattct gaagccttcc cagccatgtg gaagtgtaag tccaattaaa cttctttttt 558600 ttttcccagt ctcaggtacg tctttatcag cagcgtgaaa aaggactaat acaatatact 558660 atatagttta tggctgtttt tcatactaca atggcagagt tgagtacttt aggcctgcaa 558720 aacctaaaac aaataccacc tgccctttac agaaaatgtt tgccaaccct tagtttagga 558780 tctattattt atctctgccc tccagtgacc ctgccatcta atcatttggc ctcttaactc 558840 tctctttacc ctgagcaaat ccgtaaaata aaaggtatac ctttccccaa gtactattaa 558900 agaaaagaag aggagagggg aaaagggaaa aaggggaaaa gaaagtgagg aaagggagag 558960 gatgcaaaag aaaaagaagg aaagaaagga atttccctga tgagatccct tagtaatacc 559020 ttatcagctg ttcataatca aaattcctag aagaggaaca acagcttact tgctataatt 559080 tcttcacatt ccattgactt ttcttattac tcaaaaaaca aagtatgtta taatgtgttg 559140 atttttaaaa taaaacaaac ttttcttatt tagtcagcaa tgaaggtcaa gtgagacctt 559200 ctagtaaaag tcctctaaag tcagacacat gaaaatactt atccatttaa aacagacaat 559260 actttccaat tatttatttc tatgattgaa ttaatgggac agtgctacaa acagaagtcc 559320 tatggaataa gtcatacttg gaagatcaga gtttactcta gacaacttga cagcaatcag 559380 tttaaaaatg gtttcaccta gagggatgtg tactaatgtt agcaattaac tttgaaaggc 559440 ataaaaatta agatggattg atggatacaa ggatggttat acgataaagc aatgtaagta 559500 ttaatggcag aatctaggtg gcaggcatat gtgtgtcagc tgtaaaattt gtgttcaatg 559560 tttttttagt tcccacatat cagtgagaac atgtgatatc tgtctttccg tgtctggctt 559620 agttcactaa aaaaatgaat ttacaagaca actggaatat aagcaatgaa tacaagcact 559680 aagaagatga agccatagaa acagctgcca gaaagtgaag atgtgacagt gaacgccaaa 559740 caagtaagat tagaattaca attagaatca gaaatgacaa aaaagaaaca tgaactgtga 559800 gatgcaatat aaaaactaat ggtgaacaaa gcaaagaata aaaaataaaa acggaaagat 559860 taaaaggaaa atgtgactgt aagtagagtg acctttatat tatacagaag gtaaagcaga 559920 atgaacatgt gaggaatcta aaaaacagat ataaaataga aacaactgaa ggcttatata 559980 attagtctat aaagctagga accactgctt agtaatttct cgtaagtgga gtctctttgt 560040 tctgagacgt tgcaaaactc cattccatct caaagttatt tttaatgtta aaatttgtaa 560100 gagtgagcaa cggtatccta aatagttcta ggccttgtag aaatagactg taagagacat 560160 ctgtgacaca actatattca gtatgatgta gggtctgtta caatgggatg aagtgaattt 560220 agattatttc aagactaaac ctacaattgt gaactcatta gtaccatgaa ccgaacaaaa 560280 acctattaaa tatagaacaa gacgattttc atgaaaaaat aaatatgaac aaatcagtat 560340 tttcagttgt ttgaaatata ggttaacctt caattactgt tttatggccg ggtgcagtgg 560400 ctcacgccac gcctctaatc ccagcacttt gggaggccga ggcaggcgga tcatgaggtc 560460 aggagatcga gaccatcctg gctaacatgg tgaaactacg tccctactaa aaatacaaaa 560520 aaaaattagc tgggcgccgt ggtgggcgcc tatagtccca gctacttggg aggctgatgc 560580 agaagaatgg catgaacccg ggaggcggag cttgcagtga gccgagacag agccactgca 560640 ctgtggcctg ggcaaaagag cgagactctg tctcaaaaaa aaaaaagaaa agaaaagaac 560700 tgtttttttc atttttatag tctcaatatc cagaatgcgt gatatatgat aaaaaaaaaa 560760 gtaaaattgt agaactaaat atttacataa ttcatctgta aaatgaaaat ctgttttaca 560820 gtgtcatatt tcacagttag aaaggaagaa aaaccttaaa tcaacaaatt aactttacat 560880 cttatggaat taggaaatga agaacaaatg agactcaaac ttaccaaaaa ataaaaaaaa 560940 taaaaataaa ttacagctaa aataaaatag agaaaaatag aaaatttttg caatagaaaa 561000 aaaatcaaca aaattaggag tagctgtttt attgaaaaga tcaacaaaac tggcaaattc 561060 ttagattaag aaatgaagag aatagacaca aacagcaaca actggaaatt agaaaggcga 561120 tacaacaact gctgccacag aaataaatag gaccttaaaa gactaatatg aacaactatg 561180 acccaaaaaa atttgataac ctttgagaac ggatagacac atcaaaccca ccaagactga 561240 gccacaaata catacaactt ctgaatggac ctataactat tagagattga atcagtaact 561300 gtccaacaac gccagggctt cactgaaaac tctaccaaac atttaaaaac taacaaccct 561360 tctcaaactc tttgaaaaaa ctagaggaca gaacactttc aaaatcattt tatgaggtaa 561420 gcattactta gatatcgaaa tcagacaaat ttacaagaaa aaagaatccc taataaatac 561480 tgatgcaaaa aaaatcaaca aaataccaag aaacagaatt caacaatgca ttaaaaagat 561540 tatatttcat aaattctcaa ctggaattta ttcataaaat ccaaggatgg ttcaacatac 561600 aaaaaaatca ctttaataca ctgcattctt aggacaaaaa ccaataatct caactgactc 561660 agaagaagca tttgacaaaa atcaacaccc ttttaggatt taaaaaaagg ccagacaggg 561720 tggctcatgc ctgtaatccc agcactttag aagggcaagg tgggtggatc acctgaggtc 561780 aggagtgtga gaccagcctg gccaacacag tgaaaccctg tctctactaa aaatacaaaa 561840 actaatcggg catggtggtg ggcgcctgta attccagcta ctcgggaggc tgaggcagga 561900 caatcacttg agaacccggg aggcggagct ggcagtgagg tgagatagca tcattgcact 561960 ccagcctggg tgacaagagc aagattctgt ctcaaaaaaa caaaaacaaa aacgctcaat 562020 tcgctagaaa gatatggaaa ttacttcaac ataatgaagg ccatatatag aaagaccaca 562080 gctaatgtta ttcaatgatg aaaaactgaa agttttccct ctaagatcac aaatggaaca 562140 agaatgcaca cattcaccac ttctattcaa catactgtta gacatcctgc cagagttagc 562200 aactgggcaa gaaaaagaaa tgaaaggtat taaatgagaa aagtaagaag taaaattact 562260 tctgttagca aatgacatga tcttttatgt tgaaaactct agcctaccaa aaagaaaaaa 562320 aaccgttaga ataaaggaat tcagtaaagt tacaggatat aaaaaccaat attaagaaaa 562380 gagttgcatt tctaaatact aaaaatgaag aatccaaaaa ggaaattaat tttttaaacc 562440 catttaaaat gaaatcaaag agtaaaaaat acttagggaa tattttcacc aagcaaatga 562500 aagacatgta cattgaaaat taaacaacat aggccggacg tggtggctca cgcctgtaac 562560 cccagcagtt tgggaggcca aggtgggctg atcacgaggt caagagattg agaccatcct 562620 ggccaacatg gtgaaaccct gtctctacta aaaatacaaa ataaattagc tgggcttggt 562680 ggcgcgcgcc tgtaatccca gccactcggg aggctgaggc aggagttgtc acttgaattt 562740 gggaggcaga ggtgcagtga gccaagatca cgccactcta ctccagcctg gtgacagagt 562800 gagactctgt ctcaaaaaaa aaaaaaaaag aaaaagaaaa ttatacaaca atgctgaaag 562860 aaattaaaga caatacaaat aaatggaaag acatccaagt ttatgaattg gaagatttag 562920 tactgttaag atggcaatac tacccaaagc aatctgcaaa ttcaaagcaa tccctatcaa 562980 aatcccaatg gcattttcta cagaaacaga aaaaaaaaat cttaaaatta atacagaatc 563040 ttgaaggacc ctgaatagcc gtaacaatct ggacaaaaaa caaagctaga ggcctcacat 563100 tccctgattt ctaaagatat tgcaaagcta tagtaatcaa aacactatgg tgctggcata 563160 aagacagata tacagaccaa gtgagcagaa gagagaacac agaaataggg aaaagaggtt 563220 cttcaacaaa ctgtattggg aaatctggaa tctaacatgc aaaagaatga agttggagcc 563280 ttatctcaca ccatatacaa agatgaactc aagctggatt acagacctaa acttaaaaca 563340 tcgaattata aaactactac aagaaaacat ggagaaaaag cttcatgaca ttggacttgg 563400 caatgatttc ttgaatagat caccaaaagc acaagcaacc aaagcaaaaa tagacaaact 563460 ggggatacat aaactcaaaa atttctacaa agcaaacagt aaatggagta aaatggcaac 563520 ctacaaaaca ggagaaaata tttctatacc atgtatctgt tatttggtta atatccagaa 563580 tatataaata actcctacaa ttcaacaaca aaaaatctag ttaaaaagtg gacaaaggac 563640 ttgaatagtc atttttccaa agaatatata caaatgggca ataagcccat gaaaagattc 563700 tcaccatcac tgatcagtag ggagaaatgt caattaaaac tgcaatgata catcatctga 563760 aaccattagg atggccacca ttaaaaaaac agaaaataag tattggtgaa gatatggaga 563820 aactggaacc cttatgcacc actggtgaaa atgtaaaatg gtgccaggca ctgtggaaaa 563880 caacatgaag gtccctcaaa aaatttgaaa tagaattacc tccagttcca catatgaaga 563940 gcttggaagt caccactcca tcctaacaac aagtaaaaaa tgacaaactt aaaaataaac 564000 aaatctgaga taggataagt gaggtcacag ggcaaatgac tgcctgtgag agcagagaac 564060 aggtgaacac atagcatcac catttatctg agatgaaaaa cacaagcaga aacctccacg 564120 gggtaggaaa tcctgaagtg taatagacaa attgatgaag gctcagtgtg gacaactctg 564180 aaagctaaaa actccagagt tacccaatta tagggggagc cctacaattt tctaagtttt 564240 acatccaggc aattgaccag cttctcacag taaatatagg agaaaaatcc tcaaccctca 564300 gcaggggagg caaagagaaa tgattttcaa gtacactaga ctattccagt cttaacaagg 564360 tttgtcctca ggagaaacta gttaaccaga gcctaacctg ctggggttgt agcaaagcca 564420 aaatgatgtg ggggaagaga aataacccaa cttcaggcca ttatagctat cttgttctaa 564480 ctaagggaat gagggagggg tgggattgag aaacacttgt gaagttcaca gtccagaggc 564540 ataagctcac taaaaagact gacctaatca taagactaca gaactcttct cctctcccta 564600 caccttacaa ccacattact aaatgctcat ttacaacagt tccttttacc tagtacatca 564660 tgtccaagct atcaagaaaa aaattacagg gcataataaa aggtaaaaaa caagcaccag 564720 gaccagatac agcagggatt tggaattatc aaacttggaa tctaaaacaa ctatgattaa 564780 tatgctaagg gccctaacga actgagtaaa caacatgtta aaaaagtaga gatgaaaatc 564840 ctaagaacca aaaggaagtg ctagagataa aacacaaaca aaaacaaaaa acagaacact 564900 gtaagagaaa tgaagaatgc ctttgatggg cttattagta ggctgggcat ggatgaagaa 564960 tctctgagct tgaaaatatg ccaaaaaact acatctgggc ataaaacgtt gtaattacag 565020 aaattcaagg ataagaaaaa aatccgaagt aagccagagg gaaaaaatca ccttacctgt 565080 agaggaaaaa aagaaaaaaa agaaaaaata catgtgactt ccaacaagaa aaagagtgaa 565140 atattcatag tgttgagaga aaaaaaaacc ataaacctag cactctacct tgtgagatta 565200 ttattcaaaa gttaaaaaga aacactttct cagacaaaaa ttaaggaaat ttgttgtcag 565260 tacacctgcc ttgcaataag tgttgggaag ttcagaaact gaaatctaca tatatagagc 565320 atcaaaagaa ggaaacactg aaagtaaaat aaaacctttt atttttctta tacttaattg 565380 atctaacaaa taagaatttg ttcaaaataa tgtcaacaat tgtgcttatg catacaaatg 565440 ctcctaaact tacttattgg gttgtgtccc aataccatta taaattgaaa atatcatgaa 565500 aacacaactt atccaaattt gtgggataca gtgaaagcag cgcttagaaa gaaacataca 565560 acactgatgc atttattaga aaagaattat ctaggccggg cgctgtggct cacgcctgta 565620 atcccagcac tttgggaggc tgaggcgggt ggatcacatg gtcaggagat caagaccatc 565680 ctggctaaca cagtgaaacc ccgtctctac taaaaataca aaaaaattag ccacacgtgg 565740 tggcaggcgc ctgtagtccc agctacttgg gaggctgagg caagagaatg gcgtgaaccc 565800 gggaggcgga gcttgcggtg agccgagatc gagccactgc actccagcct gggcgacaaa 565860 gcgagactcc atctcaaaaa aaaaagaaaa gaaaagaatg atctaaaaat caattatctg 565920 agctaccaac ttatgaaact agaaaaagca aattaaatcc aaatagaagt aataaaaatt 565980 agagcagaaa tcaatgaaat tgaaaacaag atatcaatag agaaaaatca aagaaatcaa 566040 ctagttctct gaaaagatca ataaaatcaa taagcctcta gccaggctaa gaaaaagaga 566100 caaaggacaa aataactaat atcagaatga aaagagtgga catcattaca gatctcatgg 566160 acattaaaag gataatcaag ggatattatg aacaacttta cggccacgaa tttggtaacc 566220 tagatgaaat gaatcaattc cttaaaagac acaatctatt agaactctaa gaagaaataa 566280 tcttgattaa aaagcatata ttaaagaaat taaatccata attaataatg ttctaaaaga 566340 gaaggcatca ggcccagatg gattctctga tgaattctac taaacattta aggaagaaac 566400 cacaccagtt ctctacaatc tccttcagaa gacagaagca aaggagatgc tcctatctca 566460 ttgtatgaag tcagcattac tctaataccc aaaccagaca aagacattat cagaaaagaa 566520 aactacagac ccatatttgt catgaacaaa gatgcaaaaa tctttgtatt agcaaagtat 566580 tagcaaacta aattttacta caatgtataa aaagaagtat acaccagcac aaagtaggat 566640 ttatcccagg tatgcaagac tggttcaata ttggaaaatc aattaatgca attcaccata 566700 tcaacagact aaagaagaaa aatcacatga ccataccata gatggagaga agtatgtgac 566760 aaaatttaac acccactcat gatagaaact agtaaactag gaatagaggg aacaccttca 566820 acttgataaa gaacgtttac aaaaaacata cagctaacac catccttaat gatgagaaac 566880 tagaaacttt cttactaaga tcaggaacaa gaaaagaata tccccacctc accactccat 566940 actggaagtc ctagctaaga caagaaaagg aaataaaggg tatactaacg gggaacaaaa 567000 aaatacaact gcctttgttt gcagatgaaa tgactatatg tgtagaacat agacaggaat 567060 tgaaaaaaag aaaaagaaaa acaacaaaaa cctcctagaa ctaataagtg attatagcaa 567120 agctgcagga tacaaggttc atataaaaaa gttaatagct ttcctgtaaa ccagcaatgc 567180 ataagttgaa tttgaaatta aaaacacaat accattttac attagcgtgt cccaaaatga 567240 aatatttaag tacagatcta acaaaattag tacaagatat atgaggaaaa atgttttaga 567300 actctgatga aagaaatcaa ataactaaat aatgaagagc tattccatga cccgtgagag 567360 acaactcaat attgacagaa aaagtcagat ggacactact gatttcaaga tttactgtaa 567420 agctacagta gtcaagatgg tgtggtactg acaaaagaac tgacaaaaca gaccaacgaa 567480 acagaataga gagcccagaa atggacccac atagtcaaag gagcaatggc agtatttgac 567540 aaagaggcaa aggcaataca atgaagaaaa tagtcttttt caataaacag tggtaataac 567600 tgaacatcca catgcaaaaa aaaaaagagt ctagacacag gtcttacacc cttcacaaaa 567660 ataaactcaa aataaaccag agaattaaat gtaaaactca aaactataaa actcctagag 567720 gataacataa gaaaaaatct agatcttggg tttggtgatg acttttagat acggcaccaa 567780 aggtaccaac catgaagaaa agaactgata agccagactt cattaaaatt gtctacttgt 567840 ttcttaaaaa ttgttgtctt ttgcaaaaga caatgtcaag agtatgaaaa gacaagccac 567900 agatagggag gaaatattta cataagacac atctgataaa gaactattaa ctaaaatgtg 567960 taaggaggct gggtgtggtg gctcacatcc cagcactttg ggaggccaag gtgggtggat 568020 cacctgaggt caggaggtcg agaccagcct ggctaacata gtgaaacccc gtgtctacta 568080 aaaatacaaa aattagccag gtgtggtggt gcacgggtat aatcccagct actcgggagg 568140 ctgacgcagg agaatcactt gaacccaggt ggcagaggtt gcagggagcc aagactgtgc 568200 cactgtactg caacctgggt gacagagcga ggctctgtct caacagacag acagacagac 568260 agacaagaca gacagagaca gtgtaaggaa ctcttaaaat tccacaagaa aacaaacaac 568320 ccaattaaaa aattggccaa caaccttaac agacacctca ccaaagatat acagatggca 568380 attcagcata tgaaaagatg tcccacacat catatggcat cagagaaaca caaattaaaa 568440 ttataagata cctctacaca cctatcagaa tggacaaaat tcagaacact gataacacca 568500 aatactggtg aagatgtaga gcaaaagaaa cactcactca ttgctggtga aaaatgtaaa 568560 aggatagcgt catattagaa gacagtttgg atgtttccta caaaactaaa cacttttacc 568620 ataagatcca gcaattgcac tccctagtat ttacagaaag tcgctgaaaa cctaagtcca 568680 cacaaaaacc tgcacaccga tatctacagc agttttattc ataattagca aaatgtggaa 568740 gcaaccacaa tgtccttcat taggtgaata ttcattcaca aactgtgata tgtccagaaa 568800 atggaaaaag agaggtacta acaacctatg aaaagacatg gaagaaactt taatgcatat 568860 tagtaagtaa aaatagtcaa gctgaaaggg ctatatactg tatgattaca agtatataat 568920 atgctggaaa aggcaaagtt agagacacag taaaaggatc ggtgattgcc aaggagtggg 568980 agggaaggaa agataaatag gcagaacaca gaggattttg gggcagtgaa aacattctgt 569040 atgatataat ggtagataca tgtcattgta ctttgttcaa agccacagaa cgtacagcac 569100 taagaatgat ccctaatata aactacggac tttgggtaat tatgatgtat caatataggt 569160 tcatcagaaa gacatgtacc actctggtgg gagatgcaca ctggctatga gagaatccat 569220 acatgtgtgt ggaaggaggt acaggggaaa tctctgtacc ttcctctcaa ttctgtgaac 569280 ctagaactcc tgtaaaaaaa aaaaaaatct aaaaaaaaat agaatacata tgatccagta 569340 atcctacacc tgggtatact tccaaatata ttaaaaacag gttctcaaaa aaatatttgt 569400 atacccatgt ttatttcaac attacaatat tcaagaagtg gaaggaacct aaacatccat 569460 caacaaatgg ttaaagaaaa tgtggtatac atatataaca aaatgttatt cagcctaaaa 569520 gaaaagaaag aaattctgta atatgctaca acacaaatga accttgagga cattgctatg 569580 tgaaataggc cagtcaacaa aagacaaata cttaatgatt ccactgacat gaagtagcca 569640 aaacagtcaa attttagagg caaaaagtag aatggcattt gccaaggaat aggaagaagg 569700 gggaaaagaa gagttgttca atgaatgtag agtttctgtt ttacaagatg aaaaagttct 569760 agagatctgc tgcacaacaa tgtgcacagt taccacaatt gtaccgtaca cttcaaatca 569820 ttaatatggt aaaatgtgtt gtttttgaca atttttaaaa ctctacccca ttgttttctt 569880 tacctcttat ataaactgat aaaaacctgt tttatcttaa tcaattattg tatgactact 569940 gctccccaga gaaaaaagtg catgtgaaat actactactt atccatctcc tggctctgag 570000 cagtacatgt caggaacaag agggaattgt agctggaaga cagtagaaga gccataggac 570060 aagtctctaa gagaaggaag aaaaggcgca atgaaagaaa acaagtttaa gatagtagaa 570120 aagcattcaa agacggcaac ctgaggtaag gtgttttcac tgaagctttt ggggtaaaac 570180 agttttgagt tggcatgcct gtagacatgg gaagcagcag tgatgcagag gtgaacatta 570240 ctgtagataa aaacggatgg gaatttgact tgctagggac tgaggggtta atcatataaa 570300 taaagatggc agcagatttg ggaaagagtg aagaagaata agttcaggta gcagtcctca 570360 aaaaccgaga agaaactgat agctcactga aggcagacag aggaagacaa aaccagaagg 570420 cataagcttc aaaggagcag ggatttttat gctgagagag taaaaggaat agttcaaagc 570480 agcagtggag aacacgaata acgttccatg tgggaaaaga acatgtccag agcttactgt 570540 acctataacc tagcttctgt aactggaaat gaagaatctg ctctagtcag gtcatcactt 570600 ttcactactt attttacttg gccttcctaa gaaatataga ccttttggaa attattgact 570660 tttgggtcta ggacactatt tcttggtttc ctcccttctc tctggctgtt tttcagagac 570720 ttcccttcca aatctagaga catttgtatt ctccagggat cagctattag atactttccc 570780 ttttaaattt ccctttggac agtttcatct ttcaaggatt gagcaataac taaatgactt 570840 ccaaatgtct acttcagtat aaattctgct tgtcaggcta cataaaaagg gctcttcaag 570900 gaattatgat gtctaaagaa agagaaagcc acgatttcaa tatcacagag atgactacag 570960 aggaatagca ataaaaagag aggcaactta ggagaggtga atcacaaaag atgactagga 571020 gctgatgaca ctatgggtgg gaagaatgtt tcagacaggg gaagaatgtt tcagatagag 571080 gaaaatgagt aaaagcacag gggcctgaaa acatgatatt ataagacaat tccaagcact 571140 tcaagagcct aaagttcaag aaaagtttca aaaatatgaa aatggagagg cagggaaaag 571200 ccagatcatg gaagacctca atagccatga taagtaattc tttttttagc caaaagagga 571260 gtaatctaat aaaagctaaa gatcttctcc tcataaaaat acatgcacac ttcaggagtg 571320 caaatgcact cttccggaag attcgtaacc cactacattc ataaaccatt agataagaac 571380 taaaacacaa ggagtcactg aagggtttta agcaggttaa gtgactgaca aaatttgcct 571440 tttcaataac tgaaaccaaa gtgggcaaaa ctggaggcaa gcaatccagt taggtaatga 571500 ctactgtaat agtccggaca aataatgtag cagtaggaag aaaaaaaaag atgaaattga 571560 cccaggaaat atttaaaata agtagtttgt aagaggtaaa taagctggaa gagccagagg 571620 taatgggtag ggtttctggt atgggcaaca agatatgcta caagctgaga tgttagtaaa 571680 aacaagcgtt catcagcatt tagtaagtga tttatttata ttatatcact gaatactcaa 571740 ttatgttaag aggcagacag cagttaaaaa acaaagaact cggtgaatca aaaagttctg 571800 ctaatttggg gaaatagcat cccttttatt tttgttaatc tcttttgggt ttgatcctca 571860 tttatagctg acaagaagtt ctatgtacta aaggtaaact attctcatta atgttcccaa 571920 aaatctcttg gaataattaa gatataaaga aattcaaaat tcacatgatt ataaaaatct 571980 ttccttagat aatctcataa tatagccatg ttttgctcat tctactttga gaagattcag 572040 ccagaaacag ttcatccatt caactatccc tactgtgaac tagaagtatg tttccttaca 572100 tttgaaacag aagatatagg tttatatgat gcttcaggtg gtagaaaagc agggcagact 572160 atgactcgtg tcacttcctt ccacacgtga tgcctttcat gggctcctgt gtctgtcaga 572220 agaaagcaaa gggccttagc gtgctcctgg ctttctatat ccaaatgcat tttttcacac 572280 cttctcccat cagctaactc tacattactg caatacggaa cttcttacta ctcagtggac 572340 ttgttctgct gtcttctctg attccaggtg ttattcttcc tgcctagaac actatgattc 572400 ttagctattc ccaagcatcc tcaaggtttc agcttatata ccacttttaa gataattagg 572460 tattcttcct ctgtagtctc ataccaacca gtacctattc tattatatat aataactgcc 572520 tattaattaa atgggaagct gaggtatatg acctaataac ttatttactg tcgtatcctc 572580 agaacctagc aaattacaga gtctcaacag agatttttca atttctcttc tgatactgtc 572640 tcgataacag tgtcaattaa acctttctct aattatttga ccttgaaggg aaatagatgt 572700 cagactacct cctggtttcg agtatactgg aagcatacaa aaggaccttc tcaatctgga 572760 gaccaagaat atgatatgag aacctatagg agaaccactt atttgattaa agagatttct 572820 tttacttcag aaaatatttc agtatgttac ttgacccata aatgcttata gatgtgtaag 572880 tacaccgaag aagtcatata ggaaataaaa gcatccaagc tatatttcta tggtctactc 572940 tgattaaaaa gctcagctct cctatcaaat tcaagataat gcatgtggat tatggagcac 573000 agtcacttgc tacatggtaa atgctcaaaa agatgatagg tggtattacc cacattctac 573060 aggctgtgta catacttatc agtttatata tatacataaa ctgatcctaa aaaattcttc 573120 ctacatttct gcaagataat taaaaaggca gaaacaaaca ttttgcataa atttactagc 573180 ttcattcttt catgtaggaa gtagttactg actacctact gtatgccagg cactgtcatt 573240 aggcttccat tctagtggta aagaagcaaa acaacaaaga aatcaatatg caagaagtca 573300 aatgacatta aatcccatga agaaaaatgc agcaagttaa ggggaatgca gaagaacatg 573360 atcattcttt gatgcagccg gtcaggaaaa gcatcatttg agcagagagc tctctgaatc 573420 aagtgaggaa ggaagccaca tggattatca cagagaaggg tcacagggtc acagacaata 573480 gttacaagcc ttaagatgac aaagatacag ccattttaga cagagatgag caagtgcggt 573540 agagagatca cagaaatgaa aggaagccag ttcacacagg gccatgtaaa tctccagatt 573600 ttacttttaa gatgggaagc ctctgaaaag ttctgtgcat agtaaataac atggtttaac 573660 tcagatttta aaaagatcat tccggctgct actagagaat acactgtaaa gcacaagact 573720 cctgggaaac aatttctttc ttttgccaaa agatgatgcc tttaaacaga gtaaacagaa 573780 gtataatggt taaaaaaaat aaaatgaatt atgggtattt ggaaggtgta gccaacaaga 573840 tttaccaata atttgagtat gtgacataga gaaattaaaa gatgcttcca aggcttctgg 573900 ctgcacagga ggggaaaaaa gctgttattg actgagatgg caaaatatta tgagagacgt 573960 aggtttggga tgatgaaaat caggagctcc acttaggaca ggttaagttt gagaaccaga 574020 cttaactgtt ggataaatca gtctacagtt cagagggcaa gagctgacga tggaaataga 574080 agagttgtca atagacagag tcctggggca tttctgacat ttacagtaaa ctgagcattt 574140 attaaaacta acttgcttta ctgaaccata aatcacttgt tgtatttacc cctgctccat 574200 ttatagttat acatctggaa acatagcctt agtgttagag gtaaagagta aataccaaac 574260 ataaaaaatc tgatctggtt gggtgcggtg gctcaagcct gtaatcccag cgctctggaa 574320 ggccgaggca ggcagatcac gaggtcagga gttcaagacc agcctggcca atatggtgaa 574380 actctgtctc tactaaaaat acaaaattag ccaggcatgg tggcacatgc ctgtaatctc 574440 agctactcgg gtggctgagg caggagaatt gcttcatcct gggaggcagg ggttgcagtg 574500 agccaaattg cgccactgca ctccagcctg ggtgacagag caagattcca tctcaaaaaa 574560 aaaatctgaa gttactgaga aactggtatg aaatcattaa gaaaactaag gtgtctaaat 574620 taatacatac aaagagattc tacaacacgg tatttataaa tttaaacaaa atccatggcc 574680 aggcacggtg gctcacgtct gtagtcccag cactttgtga ggccaaggca gaaggattac 574740 tttggggcca agagttcaag accagcctgg gcaacatagt gagaccctgt ctctacaaaa 574800 aacaaacaaa caaacaaaaa cactgtttta gcctggcatg gtggcacatg cctgtagtcc 574860 cagctactca ggaggctgag gcatgaggat cacttgagcc caggaattca aagttgtagt 574920 gagctctgat cacaccactg cactctagct gtatcactta tgacagagca agacaatatc 574980 tcaaacaaca agcaaacaaa acaaaaaact aaagtaaatc caggtaaaat aaacatacga 575040 ataaatgaaa agatctgggt tattgcatta gttctgtttc taggcttaac tacaaaatgg 575100 tgtccagttg ttaaaaacac ttgtttaaga gtattaataa tttttttttt tactatgctc 575160 ttctacatcc taggaaattg gcaacactaa gaattcctaa aaacaaacag gagtgttaac 575220 tgtatataaa ttattattta agatgcattc aaggcgttac ttaaaatatc aaatgcatgt 575280 caaagtacaa acaacaaaat catgcttcaa caaatgtggg atgttgccat taatggacag 575340 ttagctctga ggtaaaacca agaatccttc attacctatt tttgtaaatt aggacaaata 575400 ctattaaggt attaggttgg tacaaaagta attgaacaaa cctggaccca ctcacctcac 575460 tgaaagtgct gcctggctac agtttctaga tataggaatg tgagaaatgg tagcagcctt 575520 gaaggtttag agctatattc ccataccaat tatggctaga aacttaaaac agctctattg 575580 agacattatg ggaagtctaa tttcctgtta ctctacttta acacagccaa gtaaaacagt 575640 aagaaagctt gcttaattca acaaggactg agtgccagag tgtcacctgg aaacttgtga 575700 caaataatca tgcctcacac attcatcctt ggtttttact accaaatgca agcttcatct 575760 atcctcttcc attctaaact tgactcatcc tcctaacctc ttccagaaag atctctagaa 575820 acccagaggc tttctgaaga cccataggct atcccccatc ttcaactact ttacataatg 575880 gcccctcaac ttcttagctt tcatgaaagc ctggctcctc cccaaaggca ctgcctatca 575940 tgcaaccctt ttatgtgact cctaaaactc ctaagtccac cattattctt ctaattccct 576000 gtattaaaaa taaacggcaa aattccctgt attaaaaaca acaaaaaaac agcttgtaat 576060 ttgaaactca tgtcatctaa ccgaatgcct tctctttccc tccctgttct ggtcaattaa 576120 acccacatat ttaagcctcc actttgcccc cagttacatc atcagcaaag tgacttcaat 576180 gtccctgtac atggttctat cccaatactc taggccccca aaatatttgc ctttctaaat 576240 ttgagacatc ttcacctcct catttcagca aatcactccc ttgtctttgt tagacatact 576300 aaaacctctg acaatgatca tctcagctat ctttgtaaga gtttcactca tactcatatc 576360 tcctttcacc tgtcaagaca ccaggtttgg tgacaaataa aaatgatacg tatttgggag 576420 gctgaggcag gagaatcatt tgaacccagg aagcagagga tgcagtggcc aagatcatgc 576480 tactacactc cagcctgggt gacaaagcaa gactctgtct caaaaaaaaa aaaaaaaaaa 576540 aaaaacacaa aaaacaaaaa aaaggataca tatttattgt attcacatga tgttccaaaa 576600 tatgtataca ctgtggaatg gctagatcaa gctaattaat acatgcaata cctcacatac 576660 ttatatttta tggcagaaca tttaaaatct actctcagtg atttccaaaa atacactgtt 576720 attaactagt ttccatgttg tacaatagat accttgaaca aattcctctt aattgaaatt 576780 ttgtgtcctc tgaccaacac ctctgcaacc cagtccactc acccccagcc cctggtaacc 576840 accattttac atccctgagt taagattcca catttaagag agatgtagta tttgcctttc 576900 tgtggctggc ttactttcaa caatgccctc caggttcatc cctgctgtca caaatgacag 576960 catttcctcc tttttatggc tgaagtatat tccactgtgt atacatacca cattttcttt 577020 atccatgaac acttaggctg atgctgtatc atgggtattg caaatgatac cgaaaggaac 577080 atgggagtac agatctcttc agcgcactga ttttattctt ttatttatat atatatatat 577140 atatatatat atatatatat atatatataa aaatacatat atatccaagt gtgactgctg 577200 aatcatatgg tagttctatt ttttaatttc tgagcaaacg tcatgctatt ttccataaat 577260 gctgtactaa tttacattcc tgccatgcgc aatatatctc ttgtctgcaa atcctcatca 577320 tactttaata gccattctaa tggccatttg tatgtcttat tttgagaaat gtctattcaa 577380 gtcctttgcc catttcttaa gtgaggtgct ttcttactat tgagatgtct gagttcctta 577440 tatattttgc atattaaccc cttaccagat atatggtttg gaaatactat cttccattct 577500 gtgagttttt tcattctgta gattttttct ttttgccatg cagaagcttt ttagtttgat 577560 gtgatctcat tcatcaattt ttatttttgt tgcctgtgct tcgagggggt catatccaaa 577620 aaaatcactg tccaaaccaa tgtcatgtac atttctccta tactttattc tggtagttct 577680 acagtttcag gtcttatatt taagacctta atccatttta acttgaattt ggtatatgat 577740 gtgagataca ggtctgattt cattctcatg catgtagata ttccattttc ccaacaccac 577800 ctattgaaca gacttccctt tccccgctgt gttctttgca ccctgtccaa aatcaactga 577860 tagtacacga atttatttct gtgctctcca ttctgttttg tgggtcgatg tgtctgtttt 577920 tttgtttctt ttgtttttaa aagacagggt ctcacgctgt catccaggct ggagtgcagt 577980 gatgcaatca cagttcactg ccaccttaag ctcctgagct caagcaatcc tccttcttca 578040 gcctctcggg tagctaggac tacagataca cagcaccgcg cctggcttta aaaatttttt 578100 ttttttttaa ttttagagac agggtctcac tatgttgccc aggctgctct cgaactcctg 578160 gtttcaagta atccttctgc ctcagtctcc cagagtgtgg gaatacacgt gtgagcaact 578220 gtgcctggcc tgtctacttc tatgtgacta tcatgctgtt ataattactg tagctttgaa 578280 ctatattttg aaatcagata gtgtgatgtc tccagctttg ttcttttcac tcatgacagc 578340 tttggctatt taggatctta tgtggttcca tataaatttt agcactgttt tctagttctg 578400 tgaaatttaa cattggaatt ttgatcagga ttgcattaaa actgcagatt gctttggata 578460 ataaaaacat tttacaatat taattcttcc aatccataaa cacaagataa ctttccatta 578520 tttgtatcat cttcaatttc tttaatcaat gttacatagt tttcaactct ttggttaaag 578580 ttatttctaa gtacaatcat ccctcggtat ctgcaggata ttggttccag gatctcctgt 578640 agataccaaa atccatggat gctcaagtcc attatataaa atggtatagt atttgcatac 578700 aacctacaca catcctcgtg tatactttaa atcattactt agtacctaat acaacgtaaa 578760 tgctatgtaa atagttgcta tactgtagtt tccttattgt ataagaaaac agtattttta 578820 ttgttgtatt tttttctcaa atattttcat ccaaatgttg gttcaatttg caaatgcaga 578880 accactgata ctgggagcca ctgcatgttt tgtttttggt acctattata catggaattg 578940 tcttcttgat ttttctttta gataatttgt cattaatgta cagaaattct acggattttt 579000 gtatcttgat tttatatctt acaactttac tgaatttatc agttctaaca attctctggt 579060 ggagtcttta ggtttttcta tatacaagat catgtcatct tcaaacaggg acaacaatgt 579120 cttcctttcc tactgggatg ccttttcttt ctcttgccta attgctcttg caaggacttc 579180 cggtactgtg ctgaatagaa atggcaaaag tgggcattct cgttttcttc ctgatctcaa 579240 aagaaaagct tttaactttt caacattcag tataacgtta gcagtgtgtt tgtcaatatg 579300 gcctttattt tatagaggta cattccttct atacttaatt ttttaaaatt ttgtagcaca 579360 agagaatact gaattctgtc aaatgctttt tctcaattat ctcaattatc tattgaaatg 579420 ataacatggt tttggccttt gttctcctaa tgttgtatat cacattttat ggattcaggt 579480 ctgttggata atccttgtac ccttgaggta aatcccatat gatcacagta aatgatcctt 579540 ctaatacact gttgaattta gttattattt tcttcagaat ttctgcatct aaattaagaa 579600 tacgggtctg taattttctt ttcctggaga gttcttgtct ggctttggta tctaggtaat 579660 gctcatctcc caaaatgagt ttgaaattac tccctcttct taaatttctc ataaaattat 579720 gagaacaatc tgtactagtt cttctttaaa tgtctgctag aattcagcag taaagtcacc 579780 aagtcttggg cttcctttgg tgggagatat ttttatgact gatacaatcc ttgtcactgg 579840 actgttcaca tttttcattt catgattaag cttggacaag ttgcatgtgt ctaggaattt 579900 atccatttct tctatggtaa tcaatttgtt ggcatataat tgttcagtct cttatgatcc 579960 tcttatttct tgtacttctc tggtatcagc tgcaatggtt cctctttcat ttctgattta 580020 acttgagtca tctctttttt tcttagtcta gctaaagact tgttgctttt atcatcaaaa 580080 aacacaactc tttatttttt ttatcttgag tcatctcttt tttccttagt ctagccaaat 580140 aacctgtctt ttgagttcag attcttttgt ctgcttgctc aattctgctt ttaatgctct 580200 tttgcatttt tcattccatt tattgcattt tcagcttcag aatttgttaa aaaataattt 580260 caatctcaaa atttctcatt ttgattgctg ttttcctgat tttgttgaat tgtttatctg 580320 cattttcttg aaattcattg agcttcctta aacaattact ttgaattctt tgtcaggcag 580380 ttcatatatc tccatttctt tatggttggt tcaggtgcct tattgtgttc ctttgactgg 580440 tgtcacgttt ccctgactgt tcttgatccc tgtagtcatg tgttggcacc tgcacatttg 580500 aagaagctga gacttgttcc agtctttgca gagtgacttt attgggtaaa gcccttcacc 580560 agtcagcctg tccagagatt atgcagcctg agtctaccgg ggctggcctg gagtctgggt 580620 cagcagggta ggtcctggag ccttggtaca caggtgctgc tggcctggca tcctggtcta 580680 ctagagtgag cctgaacctt ggatctgcaa ggaccagtgt gaaggctggg taggtggatg 580740 ttggcctaga atttggatca caaggggctg gccaagtact gggtttggac ccttgttctg 580800 cagtgatgtg aggccacagg ggccgatcta gagggcaggg ctgcagggac caccctagca 580860 ctagacaggc ttagagccta gggctgtggg atccagcttg gtgctggggt gggcctccaa 580920 gcttggtttg tgggtattgg cctgaagttt ggggccatgg gggcctgcct agcattgagt 580980 tttactgggg cgagctcaat gttagggtct aagtctggtg tacacttccc ctccttcccc 581040 caggtgaaca gtctctctct ccatgctggg atctcaggga ctgagggagg tgtgacacaa 581100 gtaatgtaaa actgtccttc ttaccctttt caatgtgtct tttcttatct gtgtgccaca 581160 ttcaggtaat ctctcgtctg gtttcttagc tcttatattt ttgtgtgtag acagttgttc 581220 aaattgatgg ttctacaatg agatgagtgc tgcaaagtgc tagtctgcca tcttgctgtt 581280 atctagacct caggcttttc ttaaaacaac tcaacacttt ggtctggcat cccaaccttt 581340 ccaatcatgg ccatcatcca cagcatataa attcaaatac tccaatgtta acatcttatg 581400 cacatgccac taatgattct gttccatcag ctctgctaat atccaaccct aaaataccat 581460 gcataatctt ctggctattg gagaaaagtc tttaaatttc aaatgtgata aagtctttaa 581520 tcttaactag tcactcagtg gaatgagatt ctcctactct gatacggttt ctgatttcag 581580 gtagccagcc agtcaagact ctcaacttct gatccacttc ttcacccatt cccctcagta 581640 gcttcctaag ttttcagtct tctcaaaacc tctaaacaaa ccttgtattc cacaaaatat 581700 tattaaaaaa tgtttcataa aaagtttcgt ggtcactaac ctacagtaac atactacctt 581760 atatccacta caatgactac tattgaagta cacacacaca cacactctca cacaatatgt 581820 gatggcaagg atgtagagaa actggacccc ttgtgcacta gtggtagaaa cgcaaatagg 581880 tacagttgct ctggaagagt atggcagttt ctcaaaattt taaaaataaa attaccatat 581940 gatccaacaa ttccacttct gggaaaacaa ttcaaagcag ggtctcaaaa agatatttgt 582000 acactcctgt tcatagcaac attatctgta atagctacaa catggaagca acctgagcgc 582060 tcatcaacag gtaaatggat aagcaaaatg tggtatatac atacaataaa acattattca 582120 gcctgaaaaa ggatgcaaat tttgaaacat gctaaagatg gatgaaactt gatgacactg 582180 cgaagtaaaa taagccaatc ataaaagggc aaaaactgta tgattgcact tatagggggt 582240 acttagagca gtcaaaatta gacacaaagt agaataatgg ttgtcagagg ctgtgaagat 582300 aaggaaatga ggaattattg tttaatgggt acagagtttc agttctgcaa aacagagagt 582360 tctgatcgtg actgtgcaac aatattaata tacttaatac cattgagcca aatacttaaa 582420 aatggtgaaa tggaaaattt tacattatgt gtattttact acaatttttt aaagcttaaa 582480 agacaagtca catggttggg tcacataaat ttgagaaata cattttatag tcgtttcttg 582540 cagattcaca atatataccg gcatttaaat aaggttccaa tattttcagt aaaaaaatct 582600 tgatttttcc accctcaccc acaattacaa ttaatatcac acatccatct ttacttcctt 582660 gttctaattt cattagatgg gcatctttcc tcttattcaa ggtcaatcac tatatctgca 582720 tttttctttt tttatattac ctgtatgaga gatacacctg tatttttcat tccaaccctt 582780 aatacctcga aaaactttgc tttgataatt actacctcta ttatctgaaa catctttagt 582840 cttcacaata aatcactaaa gtcttactta cttcatgtcc taaatatttg tcttaaatcc 582900 agaaaaattt attttgaatt cctattatac cactgtcatt gtcaaggctc tcactgactg 582960 aactacctta ccaccacacg tttctcttca atcctttctc tcttgcaagg ttattaaaaa 583020 tacacgtttg acaaacttac tatctaccta ctgagcaaat tctttgctga ctccctaata 583080 ccttctatca catcttatct tcttcatttt cctacctctc agctagttta tgatctaaaa 583140 gtcctcaact gcctattgtc ccctactccc tatgctgctt ctaactttgg ctcatacttc 583200 tgcctggaat aagccgctca tgcttctagc tgcctgattc ccagtcacat ttcaagactg 583260 aacttagcat ttcctggcca ctcttacttc cctgccatct acactagatt cctattgcat 583320 acctgggtac tccagtactc cttcatgtta ctattgtatt ttggatacca ttctacctca 583380 gtgactgaaa ttatttgctt ctgcatcttt cactcttgag tataatataa atttctgtag 583440 ggtgaaaact aattattacg catctctgta tctataacat agtacttgat gccttaaata 583500 tggtaggcgt tgagactgtt aaactcaact ctttcctcaa cctccctatt tccctacaac 583560 tgctaccagg gaagcaaaaa gactaagaat ttaggcgtgt gcatttatct atctagtagt 583620 agaaacctag taaactgtta ccgaggttta gagttatctg ataggaaaaa aagtaggtat 583680 gttcctatct cccatttact gctaaatgat tcctttcttt taaccagaaa ttatttccaa 583740 ataatgtgac gtaatttaaa gcagtctagg gcaactcaaa ataagaacca cagtctcaac 583800 caagttacac ttacattcgg ctagcttcaa tgtcgtcaga ctgaggttct cctgatctgt 583860 aaaatgcaat tgagaaacag ttagcaaaat attccatatt ccaaaaaaaa aggtagacat 583920 attacttagg aagacaattt tgtaaacaag atttaagcac taaataaaac agttttaaaa 583980 ttaaagatgt caacatgaaa gaaagtggtc agatcaggtg gccatacaac acatttattt 584040 taagggttgg actattaaaa aactcaatgc atgtttttta aaggaaactg taaacgctat 584100 acatagatac caacagacaa gccattataa gccataatta ttcacaaagt caaatacgtg 584160 taataaaaca cacaactaaa aaacttccta tagccaagta ttggttatcc acattaacaa 584220 aggtactcac tggtattcac tcacagtatt aaactttaga ttagtggctc agtaaactac 584280 tccctaggca gacagactaa agcttaggcc agccatgtag ttttgtaaat gaagttttat 584340 tgggatgcag ccatactcat tcatttaggt atcatctatg gctgctttca cactaaaaga 584400 acagagctga ggacttgtgg cagaaaccac atggcccata aagcctaaaa tatttatttt 584460 ctggcccttt aagaacaaat gtgccaaccg ctaccgctac tccagacaat tcaaactaaa 584520 atctaatacc ttggtaagtt taaagacact taaatcagat acaacattct aatgatgatt 584580 atcttggttc aacaatgaaa ctgtttccct aaaaatacac ttactgtatg tattacctgt 584640 caaaagtgta tcacctgagg tgaagttttg cactggatag ctgtgaatta acttcagttt 584700 taaacagttg ccagttactt tgttatttct aaatatacta ctgctctctc atgtagaaat 584760 atttaaaatt ctaagtcact aaaaagcctt tcattttcat ttcacgagat atgaatcagt 584820 atttccctat ctattcactt ttataaacag catcagcaac aatgaatgag tcaatataat 584880 attgatttct aacacttaga aattcccaaa ctagataaaa aatgtttttt gaggtcaaaa 584940 gctaaatttt caaattggca ttacaaagtc ctgatttgtg aacttctcac tgactttagg 585000 cttccaactt taagcaactc taacaagaat cttaaaatca gtcacacaca cacacacaca 585060 cacacacacg cacacacaca aacctgtttt ctaaatttct tagctaaaaa caaaaacaaa 585120 aacaaaaaac aacccctcac ttctttatca gactctcaaa attaccctca ctgcaattca 585180 ttcagattcc aaggacaaga atggaaaagg aaaaaaaaaa aaaaaaaaga ctccagcagc 585240 tcaaatattt attttagatc ttctttgcaa tgtatttaaa ttttcaattt tgcacaaaat 585300 tacataacaa ctaaaaactg gggcatgctg gaggtggcag tgacttggct gtgacacaaa 585360 tgcaaaaatt tcactccacc ctctccccca gggagcaagc aaatcaccta tgtgacacac 585420 ctggtctcca ccagccttgt gggtaagtac cccaagattg cttccaaact tgtatctccc 585480 agacagaaga gctaaaaatt gatgataacc ccatgtacca gctgactcat ttttgaaagt 585540 gcgaccctcc agcatcagat gtcatactgt aaggaggcag agctggcttg caaaacaaaa 585600 aataaacctg ctggcactga gggaagagag gcagattaga agttttcaaa cacgtaggca 585660 gcaaaacttt caaaattaac agggaaagag aagagaggga aaaaatgagg acatgatgat 585720 aggaaaataa aaatattact gcaaaaaggt aagacacaag aagaaaaaca aatctaagtc 585780 ttagaagtac aatatgtaac tgttacaaag ttttgagatc ctgaaatggg atagagttta 585840 aatacattat caaatgataa ctacatctat cttcccaatt tctgttccct aagcaagaga 585900 atatgtgaac tttggcatca aaatgtttgc caccaaactg taacatatta attactactt 585960 tttacatata ttaaagtagg ctattaaaaa ccattgataa gacaagctaa gtaatttaaa 586020 ccaatccagt atagaagaag aaggattgaa agattattac cttaaaataa atctgtcctg 586080 ggtctattaa acatagcaaa gttgttctac tcaaattgga aattgttttt taatcaagag 586140 aaaaatgaat atatgcagaa ctagcagaca tttttcttgc agtaatttat aatagtttct 586200 gtctgaatga atttctactc atcctaataa cagtatattt ctagaatatt ataaataagt 586260 taccaaagtc ccgaggttag aattcaaact ctcaaaacta tgacatatgc caggtgtggt 586320 agttcatgtc tgtaatctca gcactttggg aggtcaagac ataaggacca cttgagctca 586380 ggagttcaag gtcaacctgg gcaacatgat gaaacctcgt ctcttagccg ggtgtggtgg 586440 tgggtgcctt tagtcccagc aacttgggag gctgaggtgg gagggtcact tgagcccaga 586500 aggtcaaagt tgcagtgaac tgtgatcgtg ccactgcact ccagcctggg cgatggagtg 586560 agaccttgtc ttggaaacaa acataaacta tgaaatatat accacctagc aacagttccc 586620 aagcttgact ttggctccta aagagtctac ttattctttt actgccaagt tgctggaagt 586680 aagaatcctg tatgtgcttg taaatgcaga acatataacc taattcaaaa catataacca 586740 aagggaaatt tttgtattaa actattgact taggttatcc taaagtgtgt cagaataaca 586800 agtcagaaat tttaaaactg aaacaataac caaataacat tggataataa aatgtaaatc 586860 tcagaatgag aatcaatttt aggtcttgat ttgaatcgca gaaaatatga tcacaaaaca 586920 cccactaatc tgaatactgc agcatgagct agcaaattca aatggtggct cacttccaat 586980 aacactggtg cagcttctcc atcctgcaag ccactccttt tacctccact gtaactctct 587040 aggagagaaa agtatactag ttttattaat gttataaaaa cttctagaga aatgtttagt 587100 taaaacgttc accacataaa aggcatactt taaaatgcat attaagaaat ttttaatgtt 587160 ttctataatg tttatagtaa aatgtttaaa accttgaagt ttttttgaga aatactttcc 587220 tgtttataca tacagatagg tctttgatag tggctactga tatttttaat gagaaaaaaa 587280 gacactaaaa tattttaagg agattaaatg aagtaggtca actctcaggc ccactattct 587340 tagcagtatt cctgccaact atacattgtc ttcattttta cagtatgtat ttcactttac 587400 aatgacagcc ttttaaaggc tgtaaaataa ttcaaaatta ccttttacaa gctgtggcca 587460 ttcggtgaca tcagggtgat cacagctttg agtcactgat taaaaacagg ttgtcacacc 587520 agtctagctg ctaccttgat ctgagcgtag gcttaataac tctaataaat taaacaaacc 587580 tttggttaga acactttaat atataaaccc aattcattgt tcaaaaaata atattcaaag 587640 cttcaaatta ggtgtcaatg taaaattcat cagaagagta attattatag aaaagttttt 587700 aaggactatt ttccagcatt ttgtttttct taaatgatct cttcatttga gaaaatgtaa 587760 taattccttg tacttttatg taatgttata gtttctgaag cattttggtc aatagtacct 587820 tgagtcttat aacaactttg gctttaccta atcaagacag ataatatact aagaattaaa 587880 aaaaaaaaaa attaagcagc ctccgagtga ttaactgact tgcccaagat tttggaacta 587940 gtgttgaagg actgactaaa acccagatat actgacttcc tatcaaggga tggatttttt 588000 tgtttgtttt ggcttagttt tgctatactg ggtttcaaga tttaagtata tgtaaatgag 588060 taaagattca gaacacagat tgagatcttt caaatacgga caaattcagt caaaagattc 588120 ctaagctgat agagcaatca gtcaccaagg agggcaactg cttaatggaa tagttatata 588180 catacacata aacacacaca cataaacaca aagtctagtc ccactaattc tgtatgtacg 588240 taaagtcatt taacatcagt caccgcatgt tctcactcac aggtgggaac tgaacaatga 588300 gaacacatgg acacaggaag gggaacatca cactctgggg actgttgtgg ggtgggggga 588360 aggggaggga tagcattagg aaatatacct aatgctaaat gacgagttaa tgggtgcagc 588420 acaccagcat ggcacatgta tacatatgta actaacctgc acattgtgca catgtaccct 588480 aaaacttaaa gtataataat aataaaaaac atcagtcaaa accccttaag tactgcataa 588540 aaatatattc tactctttct tggccataaa tctactaaga tttaatttca tgaaaaagta 588600 tggcaaaaga tgaaagcata tcctcctccc tcaaccaaat atctttttaa ccccttacat 588660 ggccttagct gaacttttct gattgtcaca gttcaaattt agcaggcctc tttactgaca 588720 ctgtagttct ggcaaagata ccatacatct gaaatatccc agtatcaaaa gatcattttg 588780 tgcaactagt tctttcccct cacgattccc ctatccaggc caaatctgag gcatcaacta 588840 cggaaagatg aggaaattag gaggaagaaa cctttcataa ttaacatcct caaagcaaca 588900 atagtcaagc gtaaaaggtg gttaccagtg tggattcaga acccaatata aaacagcaag 588960 gtatctgcga ataccaacgg ttaaaacatg aatgtttgag cccataccta tgcagctatg 589020 aacgcagggc ttcaaaatcc agattaggtg aggattggcc tgaatatata aaaataattg 589080 caggggattc caataaatgg gatttatagt atctgtaaga aataacgcaa tctcccagat 589140 actcctatcc taactataca ttgcctaata agaacttaga cattgctgag gtcatatggg 589200 aaacaccacc ttccctaaaa taaacaatgt ggtcatgata cagcttcccc ttgggttctc 589260 aagagactaa tggtatgtgg aattagaaga ttcaaacaag tctaactttc catcttgtaa 589320 acacaaaaat aataaagtta aaatatcttt taattgacta attgacctca atgtaattaa 589380 agagctatat gtattttgaa aactagagtc aagtcctctc ttccagtccc ctcttttatg 589440 agatccggtg ctcaaaaggc tccaaggcca ggctggactt atgtctctgt ttggtcattc 589500 actagctgag aaatcttggg caagttactt aacctctccg agtctcagtt tccttatagg 589560 tagaactagg ataatagtac ctattccata gagctgtcat ggataaacaa gctaacatct 589620 aagtatctca gaacagtgcc tgacataatg tgctcacaaa tggctgggcg tggtggctaa 589680 cgcctgtaat cccagcactt tgggaggcca aggcgggtgg atcacttgag gccaggagtt 589740 cgagactagc ctggccaaca cggtgaaacc ccgtctctac taaaaataca aaacttagcc 589800 aggtgtggtg gcacacgcct gtaatcccag ctacctggga ggccaaggca tgagaatcac 589860 ttgaacctgg gagatggacg ttgcagtgag tcaagaaggt gccactgcac tccagcctgg 589920 gcaacagagc aagactctgt ctcaaaaaca acagcagcag cagcagcagc aacaacaaca 589980 acaaatgaaa gctattatta atactcatag cccaaaatcc aaacctgccc tctcaatctt 590040 tttatgcata ttattttacc tctcatagca cactaatctc ttgtaaattt tttcagcacc 590100 ctacctgggt ccctcataca gtcttggaag tgtagttagt gagcacctga cacaatgctt 590160 taaaaatggc aggggcccaa atttgctgaa cacatctgtc attattatga cattaagata 590220 cacatgcaat acgaattcca aaaaataaaa caaaaacata ccatatttcg ccaaacttct 590280 gaggagctgg tgaattctaa aatcaggctc ttacagattt ttaacctaaa atataaaaca 590340 cctcactcaa ttctttttac ataaacaact ggatgaactt tcaaaaaaaa aggtactaaa 590400 tttcatcata aaggcaaatt tattttctat aattatgaac atccaaaaac gtatcaagaa 590460 acaaattact gctgttgccg ggatgaggaa agcataggta ggcaggccct gtggcctgag 590520 tgctttcagc aggcaaagcc atatttccca tattcatcca taaagcttag tgccttctat 590580 ttatttactc tatcctccct ccaaaagggc taaacacata tgaaaactat ttgactatat 590640 ccctctaatc ctttcaaata cctatagcaa ttttgttttt aattaaattc tatatgctaa 590700 gcatcggcta tgttaggtac aaatctgggc atctaccact ttctagagta gcagccttgg 590760 gccgaccctc tgacccttga gtctccaatg tcaggttatt gtagcagaga aaatgcgtta 590820 aaaagttata gtataatgcc tacctggcac aaaacaggac ttcaatatac gacgataatt 590880 ataatttatt aaatcaacca cttaatatat atcaaaactt aactcttaaa aaaaaatcct 590940 gaagcttaaa gcaagcccct aaattatcac tgtaaattct taacttgttt gtatacaatc 591000 agaacattcc tcaatggaac aaaaataaag tcctttcatg tactgcatta catataaaga 591060 aagcaaatct caaaggttaa gaaacctatc cagtgtccta gaggttgatg gtagaaagtg 591120 aatacactgc atataaaaca ttttgaaata aaattaacca acttttaagg ttttagagac 591180 tgactttcaa acttcagtct ataatagaat tacctgggga aatctaaaaa tgcaactact 591240 tgggctctac tcgcaaagat tttcattcag tgcatgaagt aggggtaaat gaattttttt 591300 tttaattttt ttcagaccaa cccaagaacg cagaaatgaa tttgcatttt aacatatact 591360 tcacatgaca cacagatctc attttaagaa gccctgcctt ccaaattatg agttaggaac 591420 acataatcat ggaggaaata taccaaatct ataaaaatac agaataacaa aaactgtaag 591480 cactacaaat attaggcaca ctcacttgcc aatttaacca taagaatcct aataccagac 591540 atagttctct tactttatct cttcaacaga gggctcagtc taataatctt ataaataagt 591600 atagtctaat aataaatgcc tatgttgatc tatatctacc tccctaaaat tttcatttta 591660 ttcatttcta tttttccttc acctccttct aaagctgttt caaaacttaa tttcacaaac 591720 tgtttttttc tatcactttt tattataaca cccaacactt ctgttctcct ttgcatcatg 591780 tttatggtgt cttatattta tggataatgc tacttattaa aactgtctaa gttttgtccg 591840 tttacacatt tcacaattaa aggactacta caacaatttt cctaagtcct cctgctttag 591900 tttctcctta ttccagtcca ttctgcagtt aagacttaaa aagttttaaa tactgctttc 591960 aaataatact tgcaacataa ttccctcaac tccattagct cctcagagta ccatttcttt 592020 atcttctttc cttttactgc caaaaagacg tgaaaaccac tagctcagct gctatttttc 592080 tatctactga aatttttctt gtaaagtttc catcatttct gtatattccc agtgctttgg 592140 ccccttaatc ctacttaatt tttgtagctt ttaagactgc taatgactcc tcacctcctc 592200 tggcttccct aatgttgtat ccactcattt tcttccatct ctctaaaggc aataaggtct 592260 tctgctagtt catcttccta cctcatacat ggcctctctc caagtttctg tcaatagcca 592320 cttttcttaa cctaaaccaa ttttctgcgc aatgtcatcc attcccatag cacctctatg 592380 cttacaaacc cctaactctg tatctttaag tccttatgtc tggcatggta tgcctgcaac 592440 tacatattac caacggtaca catccatttg gatgtctcat taacatctac attcaacgta 592500 tctaatatca aactcaatta ttttcccaaa gaactcactc tgcctaatct cactgtcctg 592560 gttaaggact aaaaaaattg gtgccattca ttactttctc cccctcattt ttatttgccc 592620 taaccactgt gtaggttgat acttgttcag ccttcaaatt cttcataatc attaattcaa 592680 aaactgtcta ctagattttg agtgcctact aggtggatga agatgcagag gtagaaaaac 592740 tagacataat ttcttgccct catgtggtga aggaaatggg cacaaataaa aaccacaatt 592800 aattatgcaa taacaatgca cagttaagtg ttgtgatgga gagatacagg gggtgttaag 592860 ttgtgtactg taataaaaag tccttagtct gaagaaaagg aaaaccattc tttatgaggg 592920 acaagcaaga tttacaagac acactaagaa aaaccctgtg aggtaatgat ggtagcacta 592980 tcagtccagc tgctcaaatt ggaagattct cagtcatatt ctaaagagtc tctctctttc 593040 ccagtatatc aaattgttta ccaattgcta ccaattcatc cttagaaatt cccctacatt 593100 tctacattct cacattattc cccagtcttt tttgattgct tttagttgct tccagaataa 593160 agccaaagct cccaatcacg tcagatgaga ttctacacaa tttggtcaaa acctgccagt 593220 gcagcctctt cttacagact agaccagact tcaagagaac atgtgtatca tttgctttta 593280 tacttccagt gcttgcaaat gtttatagaa taagcatctt acaaaagaga aaatttttct 593340 cttagggaac tagctttcag tcctttagta aatgcaaggt taagattcaa accctaattt 593400 gtctgattct aaagaccacg cttattccct tgtacttgcc ttctaattta tactcaaacc 593460 ctatgaattt ccttaaaaat atctcttact ccttttttcc tcaaacttac caacactgtc 593520 ctactacagt gccccattat ttcatctggt ttcccttttg cctttatcct caactttgcc 593580 actagaatta tcttcctaaa aactcaaagt tacacatatc attctatatt caaaagcttt 593640 aacactttct catgccaaca gaataaattt ctaactcctt cacattttat ttgaggcccc 593700 tgccatgtgg ccctgacccc agccatccca gcactactgc ccactatatg acatcatcac 593760 cagttaccag atctagtccc atcatttgac tattggctat aatgtactgg atatttgtgt 593820 ttctgacttc aatgcttttg cttctgagga gacttcactc ggaaatggtc ctctatccat 593880 tactaacctc tatcccccac ccacctatca tgccatgtta aaaactggcc tcattctaaa 593940 cactgtatct cacagggtta tctaaactct tatacataat caccatctcc ttcatgtctt 594000 attatacatt cttaatacca taaaataatt tattaatttc tccttatatt tattatgtta 594060 taccttacat tacagctatc tgtatacatt tgtcagtgcc tctagttgta agctgattga 594120 tggtagggat catctcttcc atattttact tttcgtaata atggtgacta tgttttcttg 594180 acaccatacc tcccctctac aagaaaaaaa aaaaaaaaaa aaaggaatca ggacccatgg 594240 cctttgagct agttccaaat gtgactcata gatgaacaaa gataccattt cttcccaaat 594300 taacacaaat ataagtaaat gccaatttaa gaaacgtttt ttcaaagact aaatatgtaa 594360 gaataaccaa aacaattgtt tctaataatg ttcctttctc taccagatat taaaacatat 594420 taacttaaat ggaataatta aaatcggcat gcctttaaaa aactgagtat acactaaata 594480 tatgcatacc ttatgactta aaaatttcac tcttaagtat accaaacaga agtaaacata 594540 ttcacaagaa gacaatcact gaaatgttta gagcagcagc aatattctta acagttccaa 594600 accaaaaatg attaaatgtc cgtaacagca gattaaacta tggcatattc ttaaaatgga 594660 atatcacttc cattcttaaa atggaatata cagcgactat cataaacaat tactacaacc 594720 aacaatgtga ataaatctca caaatacatt aaaagaagtc agacacaact aaatgtgctt 594780 gattctagtt aaaggatgaa aacaggcaaa tctaatctat gctatgagaa gtcaggacag 594840 tggttacaca tggaagaaaa ggggtagtga cacagagcac aaggggctac gcaggagctg 594900 ctgctgtttt ttgatctgaa tgctagctaa acgggtgctc agtgtgtgaa agtgcaacaa 594960 gctatacact tagaagtgta tagcttaaaa cattctaaaa aaaaaaaaaa aaacctcata 595020 tggtattagc attagacaaa gaggtaagca caacaagcac aacagaaagc taatttcaga 595080 gaaagatccg aaagtatctg acagttgctc cttctcaaac gagaattttc agaccttgga 595140 taacaggcag cagaggacta taatgcatga aaggacaaaa acaaaggagg tgagccatcc 595200 actgcttgga tgtctgcctg gaggtaattt ccaacctgca gtcaatggag gggaaatcca 595260 gtgagaagac agcagtttta ctgagttcag aatcaagaga tcagagctga gaaagctgaa 595320 gtgggtaaaa ttgatgacaa gtgccagaca agtgcttgtc tgagaaggca gagaaatggc 595380 ttcagaaatc tgccatttga gagtccactg ctgagtacta actgtacacg attaaggtaa 595440 gtgactccat gaagctagtg aaagaggggc agtaagctga aatattccca gtacttataa 595500 aggactggga gactcctaaa attctctcta acctgagtga agagaacacg gtgacactgg 595560 gagcatttag taaagactca gaaggatcat gccttaggta ggagctacta ccattaaagc 595620 aaagccttct ctagacaaac tccaatgtag ccctgaaggg ataaaactga ccagcaagtt 595680 atttaggtgg ctacaaaaca aaacactcta aaagaaaaca aaatctagac acccaacaac 595740 aaaatattac aatgtccagc atccaatctt aaaaaatcat taaatatgta aaaaacaaaa 595800 aataaaataa aataaatact aggaaaatac aacccatgac caagagaaaa aaccaaccaa 595860 caaattcaga gtgaaaaaat tcaagaaatc aataagtaac ctgattttca aacagctatt 595920 acaaatatgc tcaagaattc aaaaaaatac atgaataaaa tgaatcaaat ggaatttctt 595980 gaaatataaa gcgaaatatc tgaaattatt taacaaggga ggagaaaaaa cagtaaaata 596040 gaagacaaag caaactgaag cacagggaaa taaaaagact gaaaaataat gaatatgatg 596100 ttaatgacct gtggataata ccaaacagtc taacatatgt gtaactggag tcccagaaaa 596160 agaggaaatg atgaaagagg agtaaaggtg gtaaaaaata tatatataga agaaacaatg 596220 gcaacaatct tccaaattta aggaaaacca taaatgtaca gattcaaaaa gaaaaaaaaa 596280 acaaaacccc aacaactctc agcatggtaa tcattgtgca aatatcatag aacgtactta 596340 cacaaatcta gattagatgg tatagcttac tacagaacta ggatacatgg tatagcccgg 596400 gtgctcctag gttataaagc tgtacagcat gttactatac tgaatgaata ctgtaagcaa 596460 ctgtaacaaa gtgtaagtat ttatacatct aaacctagaa aaggtacagt gaaaatatgg 596520 tggtataatc ttaaatgact attgtcaact atgatctcgt tgactgaaat gtcagcatgc 596580 ggcacatgac tgtataacca gacttctcat caaaaacaaa tgctgaaaga aaaacacatc 596640 aactaaccaa gaaaaaagaa acatatatgt ccacacagag acttcttttt ttacacaaat 596700 gttcattgta cctttttata atagctggga actgaaaaca gcctggaact gaaaacagcc 596760 caggtgtccc ttaacagatg aagtcacaaa ccaccgaaac attcaacaat atggatgaat 596820 ctcaaaaaca ttatgttgag caaaaagaaa ctttttacaa catataagta ttgtatgact 596880 ctacttacat aaagttctgc gcaagctaaa ctaagatgaa aacaatctga acaatgttag 596940 gttctagggg tggtgtgggg ggaaggaata actaggaaga ggtgtaggtt ctataccctg 597000 atagaacttt ctggcaaagg tgtatacatt tgtcacagct catgaaatgg tatatgtggt 597060 caactgtatt ttccaaagat ggtcacaata gaagccattc cacatgctct taacaatgta 597120 acactgtcat tttttcatca ggtggtggag tctatggccc ttctccttga atctgagtga 597180 aattagtgag tctttcaatc caaagactac agtcatacct caactatcta cagaggactg 597240 gttccaggac tcccatggat cccaaaatcc aaggatgctt cgaatccctt atataaaatg 597300 gcatggtatt tgcatataac ctacatgcat cttcaaatat gttaaaccat ctctagatta 597360 cttataatac caaatacaat gtaatgctat gtaaacagtt gttacaatgt attgtcaaag 597420 acaagctctc cttgccaatc cctgaccaaa tgagagattc atgagcaaaa taaatagttg 597480 ctgatattta aggcactaag tttggggcaa tgtattacac agcaataaat aactggaaca 597540 gcatagtaaa ttctagttaa aaatactaaa ctactaagtt ttagttaaca tacatgctca 597600 agttaagggt gtggtatact aacaactgca acttactttg aaaagcataa aaaaagacac 597660 tagaagaaga caggatggat agatggacaa gatagaagac aataacaaat agaacaaaat 597720 gttgtgaaat tatattctac aattatttta aagtctgtgt ggtttgaaaa attgtacgat 597780 aaaatgaaga gtgaaataaa gacatttcca tacaaacaaa agctgaaaga ttttgtagcc 597840 agtagaccta tactttagaa atgtttaaga aattttttca agtaaaagga aaataacacc 597900 agcaacaaac ttggatctac aaaaaggaat ctccacaaag aaaaataaat aaaaatggta 597960 aatatgaagg taaatataaa ggaatgttat tcttagtttt taagtttctt cgtaagacaa 598020 ctggcctttg aaagaaatag tttcaaacgc tgctgtggaa tctataacac atatagaagt 598080 aaaatgttaa gatcataata ccaaaaagaa tgagggagag taaatggatg tatactattc 598140 caaaattctt acattataca ttaagaggaa taatattttt gaaggtagat tgaggtaagt 598200 taaaggtgca tattgtaaat cctagaagta tcactggggg gaaaaaaaac agagggacaa 598260 gctaataatg gagacaatac aaaattccaa aaatgctcca ttaaccgaaa agaaggcaga 598320 aaaggaagaa aagattagac aaatagaaaa caaatagtgt cttaaacaca attatattgc 598380 caactgcaat aaatgtaaat ggacttaatc aaaaagcaac gatcgtaaaa agtcaatctg 598440 aaagcaagat gcaactatat gctatctaaa agaaagacat taaatgacca ataagctgaa 598500 aataaaaaca cagcaaaatg atataatgtg caaaaattaa tcataagaaa ggaatggata 598560 cactaatatc aaagtagact ttagataagg aacattacca gcgataaaca gagacatttc 598620 ataatgataa agacatcaat taatcaagga gatctaacag tcctaaatgt gaacacacct 598680 aaggacacaa ctttaaagac tttgcttcaa agcatatgaa gaaaaaatga acagagcaga 598740 aggaagataa actcaaaatt atagttgaag atttcaacat tcctctctcg gtaattagta 598800 agtggacaga aaatcagtaa ggatacagaa gaaatacatt tatctatctg acaaagaaca 598860 tatgttctga aaagaatgtg aaaatatttg aacagacaca caaaagaaaa cttctcaaca 598920 gcagtcatga agaaaatgta aattaagacc ataatgactt tttacaccca ttagaatggc 598980 aattatttta aataaaaaac agaaattacc aagtgttaga aaagatgcag agaaattgga 599040 acccttattc actgctggtg ggaatgtaaa atggtgcagt cactgtggaa aacagtatgg 599100 cagtctctaa aaaaattaaa catacaatta ccacatgacc cagcaattcc actcctaagt 599160 acataaccaa aagaattaaa agaagggact caaacagata cttatatacc aatgttcata 599220 gcagcatcat tcacatagtt aaaagttaca aagagtccaa atgtccactg acaaataaat 599280 aaataaaaca aaaagtgata tatgcacaca atgaaatatt actcaacctt aaagaatcaa 599340 atttggatac atgctacaac atgaatgaac tttgatgact gatacggttt gaatatttgt 599400 cctgcccaaa tctcatgtta aaatataatc cccaatgttg ggggtggggc ctggtgggag 599460 gtaactgggt catgggagca atccctcata gcttggtgct ctccttggga tacagagtga 599520 gttcgcagat gtggtcgttt aaaaagggtg tgccacttcc ccaccctctc tcttgctcct 599580 gctctcgcca tatgacacgc ctgctccccc tttgccttcc accatgagta aactcaccat 599640 gagggctccc cagaagctga gcagatggtg gcgccatgct tgtacagcct gcagcaccag 599700 gggccaaata aacttctttt ctttttaaat tacccagtct cagatattca tttaaggcaa 599760 cgcaagaatg gcctaacgca aggacattat tattattaaa tgaaatgtgc cagacacaaa 599820 aggacaaaaa tcgtatgatt ccacttatat gaagtacctg gaagagtcaa attcacatat 599880 gaagtagaac agtgattacc agcagatagg gagagtaggc aatgaagagt tactgtttaa 599940 tggatagggt ttcagactga gaagatgaaa aagtttcaga gatggatagt ggtgatggct 600000 gcagaataat gtgaatgtac tttatgtcac tgaactgtac acttaaaaat agttaaaatg 600060 gtatatttga tgttgtgtat tttagtacca cttaaaaaaa aacactgcaa tgggatacca 600120 ctacacacct ctcagaacgt gtgcaattaa agactgagaa catcaaatgc tgacatttgg 600180 agaactggaa ctctcataca ctgatgatgg gaatgtaaag tagtataatc atctggaaaa 600240 tagtttggca gttccttata catttaaaca taaacttacc atgtgaccca gtaattccaa 600300 tttaaggtat ttaccctaga aaaatgaaaa catatgttca cacaaaaaca tgcacacaaa 600360 acagtacctt tattcgcaac agcctaaaac tgaaaacaat ttaaatgttc accagaaaat 600420 gaatgaactg tggtatagtc atattgtatt taaaaaaacg aaacaaacaa aaatctgtga 600480 caaacacaaa ttggatgaat ctcaaaaaca tgccaagtga aagaaaccag gcatggaaga 600540 gtacatgtta cttgattcca tggatatgca attctagagt aggaaaacta ataaacagat 600600 cagtggttgc ctggggccaa gagggagaaa tgactacaga caggaaggaa ctttttggag 600660 gtaattcaat tgttctaaag cttgattgta gtagcagtga tagtgtatat atttatcaaa 600720 atcaataaaa ctatatagtt aaaatgggtg catttcattg tgtatcaatt atacatcaat 600780 aaacttgatt tttttcaaag tttgtgagaa cttaatatag aaaaaggtgg cattatcagt 600840 ggggaaagga tgccttacaa gacaatcagc tacccaagtg gaagaaaata aaaggtagat 600900 ataattccca aaccatgaca aatgcaatcc agatctaaac catatcatac catatccaaa 600960 aatatgctga atgctcatat ctaactttct aaattaaagt ctataaagta aaatcacaaa 601020 agtatcagaa gaaaatacaa gagattggcc aggtatagta gctcatgcct gtaatcccag 601080 cactttggga ggctgaggtg ggaggatagc ttgaggccag aagtttgaga ccagtctggg 601140 caacacactg agatacgttc tctaccaaaa aaaaaaaaaa aaaccaacca accaaaaaaa 601200 aaccaactag ctatagtggc acatgtctat aatcttagct acttgggaag ctgaggcagg 601260 aggatcactt gagcccagga gtttgaggtt gcagggagct atggttgctc cagcccgggt 601320 gacagagtga gatcctatct ctaaaaagtt tttgtaatat atatatgaga tcatatttat 601380 atcaactttg ttagcatgct gaaacccaga aaccataaaa gatggacaga tttgcctaca 601440 taaaaacttt aaaatttcac atgactagat actataaaat taaaggtagg tagagataat 601500 atttgcaaat tataataaag aattaaatga tatataaaga atgcttacaa atttaaaaaa 601560 caaacaccac aatagaaatg gaccaaaaaa ccaggcaatt tcccaggtta tttataaaga 601620 cttaaacaga ttttatatat acatgaatca aaacaaggta aatgagcagt ccctaatata 601680 ttttaaggaa tgaaacttgc taaaattatt ttttaaaagg taattggcaa aacctatcaa 601740 atatttagat tgacatgatc taatggcctg acatcttatt tgtaggaatc taccttacag 601800 aaaaaataac aggtaccatc attgcaaaag caaatattga aaacaaccga atttccaaaa 601860 caggcaaagg gtctcataac atcatgaact ctcagagtta attcctagtt cagttctaaa 601920 gattgagaga acacatcaga tttagagtat tccatctcag gtttctcaag gacaattttt 601980 cattaaggcc taatttatta tattttaaaa catgcttttc catccttttt tctgtttttc 602040 ctcttttccc cccacaagct tatatggtaa aattacctgt agttaagtgg gcatgtgata 602100 tgatgcacag atttaatgca ataatttata agaattatcc aactccattc tctcagctgc 602160 tctggtcaaa aaactttggc atcatgtttt actcctccct ttatttccca ctttcatctg 602220 gtctactacc aaatcctatg gactctattt caacatatat caagaattca accacttctc 602280 accaccctca ctgtgaccac tctgtccatt tcagtcacgt cttaatctgt actaatggtc 602340 taccaattgg tctgtttctg cccttgtccc ctttttcagt ctatgattaa cacagcaacc 602400 agagtgacct tgctaaacat aagtcatact ttttcactac tctgctcaaa gacttccaat 602460 agcttcccat ctcacttata ggtaaaaatc aaacacctta ttatgatcaa aatatctgta 602520 ccctccattc tctctatttc ccatcaatta cttttctaaa gctacactgg ccacacctcg 602580 agttcttcaa acacatcagg cactctcact ttggggtttc cctattcact acactctgcc 602640 tgaaatgctc ttcccccaaa tatccacatg gctagctctc tcatctccct cagttcttca 602700 cccaagttac catttcagtg aagttttctc tacctaccct atctaaaatt tcccatcatc 602760 cttttcacct gcaaacactt cccttatttg tttcttctcc ttagcactat gtaacatata 602820 ttttacctat ctttatgatc tctttttagg atttaagtgc catgaaagca aaggactgag 602880 tgggttttat acactgctgt ctctaccagg acctagaaaa aaaggcccac tacacagtag 602940 gtgttcaaga aatgtttact aagtgaatca gatggatgtg tatgtagcca accatttgaa 603000 agattcctat aacacagtta agaggaaaaa aaaattatat gaaacacaag ttttagtaca 603060 caaaaatcta tgcacaagga attaaaaacc tgaaatgaaa ttttaaaaaa ttcaatttgc 603120 aataccatca aaacataaaa ttcttagaaa taaattttta aagtaataag tacaagacct 603180 gtatactgaa aactacaaaa catgaaagaa attaaagaac accttaataa atggaaagat 603240 atcccatgct catgaatgag aagacagtat taaggtagca atacttccca aatagaccta 603300 cagattcaac acaaatccaa gtcctattaa aatcccagtt gcattttttt gcaagctaac 603360 cctaaaattc tatggaaatt tgagaaaccc agagacccaa aacaattttg aaaaagaata 603420 agttagaata ctcacatttc ctggtttcaa gacttactac aaagctacag taatcaagag 603480 tgtgtgttac ccaaaaaaaa cagacataca tgtcaatgaa cataccttga aaataccatg 603540 gtaagtaaaa gaacccacac acaaaaggac acatactgta tgattcccat ttatatgaaa 603600 tatccagaat aaataaattc atagagacaa agcagattag tggtttccag aggccaggaa 603660 agaatgggga atggctgcta acaggttagg atttattttg gggatgatga aaatgttcta 603720 aaattcaata gtggtgatgg ctgcagaact gtgaatatac taaaaacttt aaaagggtga 603780 attttatagt atgtgaatta tctcaataaa gctattaaca gttttgaaag ttagagaata 603840 tgtttggtag gatttttttt aaatactgcc tccccaaaag gaaaaaagct gtatgtatat 603900 cagtactttt acagctatct tacattttat atttgattgg taatttcctt ccaggcattt 603960 ttttccctct acagttaaac acacttaaca actgttaagt tttagaattg gctatgaagc 604020 gaagagaaac ctttcatttc ttcttatact taaaaaaaaa tagcttttta tttttctttt 604080 ctgtatttcc tcatcctcaa aaatagattc tacacaccaa tatttgaggg atggtggggc 604140 aactaccaca aaatacaaga ggctctcttc tggaaatgta aaaatgttag aattcctagg 604200 aacttttcat gatttatgag cctaacctaa catttaaaac tgagcccatg ctggtaaatc 604260 tgggctacac agtcatacat acatagaact ctggaatcac aacacatcca ctgtgcactg 604320 gaagagtact gtaatctcct tctaatgtgc accttggctc tcccctccct tgggttcttt 604380 gaaatttttt ttttaaataa ggtatgttta tttcttattt acctactaac tacagaaggt 604440 agactcacaa tgtgccaata ttaaaatgtt atcattcctc attaaaatat ttacttaagt 604500 gttttattac atgacttacc agcaatggaa gaatctcatc tgagagtagt tctcaactgt 604560 catctatgaa aatctttaga aataccaaat catcagaatt actttaattt cctggctttt 604620 aatcataaag cattcctact ggtcaacaat tctacaatct gaaaacaggg acatctgtac 604680 catatagtcc caatgattta ttattctgaa attttcctct gggttatttt tacactgtaa 604740 ttagagttca aacttccata gcgcctagcc taaaattaaa cccagaatta tgccaattta 604800 tgcctgctat atatgcacac acaaaagact tataatgcaa tatactaaaa gaactaaagg 604860 taggtgggtt tttccttgaa ggaatcatag ctacattatt ttcaagttta atctgttaca 604920 ttcacctgcc tatcaaataa atgtagcact taaacgcata aaacaaaatt tgatttagtg 604980 acaaaaaacc attagcttct aatttaactt caaaacgctt ttcaaaaaat ctaccccatc 605040 taattctaag tgaaccagac cacacttgat agaaaactgt tgttctaaaa accatacgta 605100 cttaacacaa acagtaaaca tatgagaaca tttagtcttc tattaatgtc ttacaaaata 605160 tttcaatgtg gctggttata attttttttt ttttaaggga cagggtctgt caccgcggct 605220 ggagtgcagt ggtgtgataa caactcactg cagcctggaa ctccagggtt caagcaatcc 605280 ccccacctca gcctcccaag ctgggctaat tttatttttc atagggataa ggtctcactt 605340 tgttgcccag gctggtctcc aattcgtggc ctcaagtgac tctctcacct ctgccttata 605400 tttccgtttg agctgttatt atcaactgga gtaacatttc tagttgggga aaaaagaact 605460 gatccttatc tgtagatgaa cacttataca ttcagcactt acaaataact gaatgtgggc 605520 atgaaaaaaa gaatgacaga tgataaacat ttactgttct caaaataaat tacctaatct 605580 cagttgagat aaacacgact cagaattcaa ttaacagtat aatataaaga agccccaaac 605640 caatgagtgc aaaaagaaag actctcaagg aaggcttccc tgagtaatat ttaggttgag 605700 ccctataaga tagaaggaag atggataact caagaaacta aaagcagcct gtgtggtaag 605760 atggtactga ccaaagggga atgcacagga aggtaaggct cagaaagtag acagaaccct 605820 atcaaagcaa aattttaaat agaaagcact cttctatttc aaaataactg ttatttgttc 605880 acaataatac aaaggaatta taaactacta aaactaacaa accaaagtgg gcaacatagg 605940 aagaccccat ctctacaaaa aaaaaaaaaa aaaaaaaaaa aaaaacccac aaaacttagc 606000 agggcctgga ggtgcctgcc tgcagtccca gctacttggg aggctgaggc aagactatcg 606060 cttgaggcca gggggttcaa ggatgcaggg agctatgatc atggcactgc actccagcct 606120 ggggaagaga gggagaccct gtctcctgga aaaaaaaaaa aaaaaaaaaa ggtgggtggg 606180 gtggggagaa ttcaataatt aggacgaata gactttaaaa tgtagtttat acacacagtg 606240 gaatactact cagctataaa aataagaata aaaccctgta atttgcagga acacggatgg 606300 aacaagaagc cattatgtta agtgaaataa gccaaacaca gaaagacaaa taccacatgt 606360 tctcactcat acatgggcta aaaaagtata tctcaagaag ataagcatag actggtggtt 606420 actagcagcc gaagtgggga gtgagaggac aaaggcagaa gaacataact gtatttatta 606480 ttgctgaact gtacacttaa aaaactgtac acttaaaaaa tcattaaaaa tgaactgtac 606540 acttaaaaaa gatggtaaat tatgtatgta tatttaacct caatacaaaa ttttaaaaat 606600 tcaatactta atgctggaac aactagcttt tcatatttaa aataaaaaat cctaactcct 606660 ttcagatgaa cctaaatgca aataacaaag agtaacaaaa aatcctcaac tattagcaga 606720 caatataaaa agaggatttc ttaaacaaaa agcacaatca taaagaaaaa gacatgattt 606780 ttacatcaaa aattaaggct catactacca gagaatacta caatgggcag gattttatat 606840 tttactctta ttctggtaac tttctttggc tgcactgtaa agtaagaagg ttggatgaaa 606900 tgatcttcat ggtccttttc aacataaatg ttgtacgata gtgtgccttt cctttaaaaa 606960 catttatttt tgagatattt aaaacataca gaaaataata aatttcctat ccttttacct 607020 acgattcaga ataatcaagc aactgtaaat taaaatgaga tagcatttca catgcctcaa 607080 attagtaact attttaaaat ctgacaatcc caagtatggg tgaggatgct agaaatgccc 607140 acataatgct gataaagtat acatgggcat atccatttag gaaaagaatt taccaatatc 607200 tagtaaccag caatttcact tctacggttt ttcccaaaac acctgcacat acactcatgt 607260 aaaaataaac actgcagcat tatttataat agcaaaaaga aaacaactca aaatatccat 607320 caatagtggg acacatacat tttatctatg cataaaatga agtgccatac agcagtgaaa 607380 ctgaataaac tacatgtaca cgcatcaaca tatacacctc aaaaacttga tactgagttt 607440 aaaaaaatca agctattgaa agacagcgtt atacatgtct gtaaaaattt aatacaaaaa 607500 ccaacaccac atatcactta cagatacatg tacacatgta tagtaaaagt ataaaacaag 607560 gatgtgaaat ttacttaaga atctcaagac agttgttact ttgtgtagag acgggtaaca 607620 ggacttgaac agttggggtt gttaaaagtg attatataac tgcatccttt cccccaaggg 607680 ataaaaatgg acataattta tatttccagg tggtggataa ataggcactt gctatgtcat 607740 tttctggatg ttttaaaaat tttacaatta aaacatatac acttatttta aaaacaaaca 607800 aaagacatat tagcatataa tgtccaagct gataattacc ttggaagatt atctaatata 607860 aacctcccta cttcactaaa aacaaaatta caaaagatat cagaataaaa atatgataca 607920 ggctggacgc agtggctcat gtctataatc ccagcacttt gggacgccaa ggcaggagga 607980 tcacttgagc ccaggagtca agaccaggct gggtaatata gtgaaacttc atctctacaa 608040 aaacaaacaa acaaacattt ttttaagaat gtaataggat tggtgtggtg gctcatgcct 608100 gtaatcccag tgctttcaga ggttgaggca ggcagatcac ctgaggttag gagtttgaaa 608160 ccagcatggc caacatggtg aaaccctgta tctactaaaa atacaaaaat tagccgggcg 608220 tggtagtgca cacctgtagt ctctgctact caggaggctg aggcaggaga atcacttgaa 608280 cccaggaggc ggaggctgca gtgagctaag actgcaccat tgcacaccag cctgggcaac 608340 agggcgagac tacatctcag gaggaaaaac aaaaaaaaac ctatatatat atatatatat 608400 atatttatat gtattatata tatataatac atatatataa gattatatat atattatata 608460 tataatacat atatataaga ttatatatat attatatata taatacatat atataagatt 608520 atatatatat tatatatata atacatatat ataagattat atatatatta tatatataat 608580 acatatatat aagattatat atatattata tatataatac atatataaga ttatatatat 608640 aatatatata atacatatat ataagattat atatatatta tatatataat acatatatat 608700 aagataaata ctattgtagc agggcaattt tggacaaata ctaggttatc tgaaacagca 608760 ctttggggaa ttagatcttg accatttaag agagagatta gccccagttt ctcaaaatct 608820 ggcactgact agcaatatgg acaatgtgtg caccgccctc gttccacctc ccctcctagg 608880 aatgccatgt caaattcagc acaggcatag gcagtaaaac tgacccctag ttctgcctat 608940 cactatttaa aattacttta agtgttgagg actgtcccca cagcagatat ctaaaagtag 609000 gcctgaaaga actagaaagt agttcatgca tccagcagtt acaagtgcct aaaactgtac 609060 atgaaaaaac aaaacaaaga aatgaactga gagcaaacat ttactgtttt cttataatct 609120 tcaatccagg atttaagaaa ttatttaata tcagttgaga tacgtgacca acccattctc 609180 cagctgagat ccatctattt ttaaattcac tcccccagcc tttcattcag cctaaaagag 609240 ggaataagaa tgggaaggtg ggaaggactt atcccatact gagttaaata agaccacaag 609300 atcttttcat ttttacaata tttgaaatac agtacactga gcaataaatt taaagaaata 609360 tgcatgattt gaaatgcaga aatcttgatt tatgtgtata aaagaccaaa attagctcag 609420 ttcgtctaat acactacact taagtgttct tcaatactac agtcaacttt tcagaaatat 609480 tcccattctg tgaagcagga tgtattccta ccttgattac caaactttat ccacgtaact 609540 tcctattctc ccactctgtt ctttaaacat gttcaacatg ttacagagat ggcaaaatgt 609600 gttacaaaag ggaatgagaa tgaagcagct taagtaatta ggaaaacttt acacttctta 609660 gaaactgaat ttgaatgatc ttaaacagca tattttcttt tcttttcttt tcttttttga 609720 gatgaaatct tgcttgccca ggctggagtg caatggtgtg atctcagctc actgcaacct 609780 ctgcctccca ggttcaagcg attctcgtgc ctcagcctcc caagtaactg ggattacaga 609840 cgtgtgccac cacgcctagc taatttttgt atttttagta gagacagggt ttcaccatgt 609900 tggccaggct ggtctcgaac tcctgacctc aggtgatccg tgtgcctcgg cctcccaaag 609960 tgctgggatt acaggagtga gccaaggcgc ccagcctaaa cagcatattt tcaatcacca 610020 acacacaaca tgaccactga cttcagaaaa ctaggaaaga aaaatgttac ccaattaatc 610080 tttgtgtgaa acaggattta tccattagta tacgtatcac ataccataga tgcacaaaag 610140 attttttcaa ttcccaaaac aaaaacttaa aatatttagc aaagataata taaaaatcct 610200 tatttatggc acgctgtaag attatcaata ttggtgcata taaccacaga ggcacaatag 610260 aattcttagg aaaaatgtat taagacaatt aacaagctgg aaataaccca tatttcccct 610320 tatgacccat tagctttata tagaaaacac tgctgtgcac ttcatccttt gctttctaaa 610380 gaacagcatt atggttcaca tctgttaaga gacaaaaaag tatttgttgg aagtacgaaa 610440 ggaagaaatt cctgtactgt tacatgcagt gccaaaggaa tcatctgaga agaaaataaa 610500 gaacatgagt ttaacatgag ctttagagag ggattacaag agtgcaagaa agtgacaaaa 610560 tgtgacatat gtccatagtg aatacatggt gctttattgt tttcagtatt tctatattta 610620 attaggaggt ggaaagtttc agaatttatt ctgcatcaca aagattataa aaatatatga 610680 gttggggtgt tggctacagt acacaaaggc aattctaaga ctacttatta acagaagctt 610740 gaaatggaaa agccatccct tctgatttca ttacatgaaa agaacctgtg tagaagtaca 610800 gcaatggtag catcttcatt cagcccacag ctatgtaatt tgtatgcaag agtgcttgtc 610860 ttaaatatga aaaggaacat cctgaattgc tgaaagtata tacaacgggc acacatccag 610920 aactaggaaa gagctaccaa gcctgcatgc tacgaagaca tgggtcaaaa aatttttctc 610980 atgtttggtt tctataacta aagtctgtgc tagactaacc tcaattgatc ctgaggagat 611040 gaacttctgg aacacacaaa actgttaaga gtcacagcat tagactctac actgtccagc 611100 caacagtttt aagaaaaatt ttatcctact tgtatgagtg ttcagggctc atatactacc 611160 tctatgctct tacttgaaac acagatgcag accttaataa ataaagtctt acatcagact 611220 ctcttctata attcacatgt gattccttac acgagattcc tgttcagatt tcctgaaaat 611280 gaactatagg aataatctta tccaatatga ttctatgtcc cctaaaaata tcttttcctt 611340 tcaggtcaat cttatgattc acttgccatt gatcagatta acacaacagg tctggtacag 611400 caaattacaa aagagatttg acttttgatt aatacactga ataatgtatc acaaactatt 611460 aagatccatt gtccatgtca aatggagttc acatatttaa aatgaattca cacactaaaa 611520 attccccaaa acaacgtttc taaaaagttt tttttttttt ctttgagagg cagtctcact 611580 ctgtcgccag gcagtagcat gatcttggct cactgcaacc tccgcctccc gtgttcaagc 611640 gtttcccctg cctcagcctc ctgagtagtt gggactacag gcatgcgcca ccacgtccgg 611700 ctaatttttt ttttgtattt tagtagagat gaggtttcac cgtgttggcc aggatggtct 611760 cgatctcctg atctcgtgat ccgcccgcct cggcttccca aagtgctggg atgacaggcg 611820 tgagccatgg cacttggcct ctaaaaagct cttaatctac attttcaaga atgatcacgt 611880 ttgaaaagca tactctttta aaacaaagca actatcactt tcatttgaca aaagaaggaa 611940 cgaaggcttc aaaagctaaa taacctgctc atgaccatta cgaagctagt taaaacaacc 612000 tcaagaccaa aagacagtgc tcattccatt tcaatgactc tgatgcactt aaaattttat 612060 aaataatttt tagggatatc agtcataagg cttagaatca aatagtaacg actcatgtac 612120 aaagaccagt attttttaaa aatgctcagc tgggcatggt agctcacacc tgtaatccta 612180 gcaccttggg aggccaagcc gcttgagacc aggagtttga aaccaacctg aacacggcaa 612240 gaccccatct ccacaaaaaa attaaaaaat aaaaaaatta gccaggcatg gtggcatatg 612300 ctaatcccac ctactcagga gggtgagatg ggaggatcac tccagcctga gactgcaatg 612360 agttatgaca gcaccactgc actccaactt gggcaacaca gcgagaccct gtctctaaac 612420 aaataaacaa taagtaaaat aaacaaaaag aaaatgctaa ctttacttca ctctcagata 612480 ggcctaataa ttaataagct tctttttgaa ttattatcca taatggcatt tacctgttat 612540 tgataactca gatcaaagca ctactaagca acatttttga tagcaaatga aaacaaaagc 612600 tggcaaagaa actgtgtatt aataagtcat ttgattaaaa aaaaggactt ggccaggtat 612660 tgtggctcat gcctgtaatc ccaacacact gggaagctaa agtaaaagct gaggagttca 612720 agaccagcct gggcaacaca gtgagacccc catctctata aaacaaaaat ttttaatatt 612780 atctttttac aaaggactta tttatatggc atcttcaagt atttcaaaca tttcgtgttt 612840 ggattatgga atatgtctcc agaagaatta acactatttc tatttaaggt aattttacat 612900 catttccttt attagaagaa ataacagatc tgcagatggc attttgtgaa ggctgccttc 612960 tattaatagt gtacaaaaca ctcatatgtc tccaaaaagg tgggtgagta atcacaaagc 613020 aagtataact attcatccca aaaggtagga cagaacatgt gccaatgtgt gcagagtcct 613080 gaactagaga catggactct ggttctggtt ctgacacctg ggtgacttta agaaaatcat 613140 tttaaagctt tgcactccaa tttcctcttg tataaaatga ctggagcagc tgacctcata 613200 gacaatccta ctcaggtagc atctatccat gtactgccag aagacagaat gataatcatg 613260 ccccccaaaa ttagagtatt tgaagacaac tgccggagta aaaattttaa attctatata 613320 catacacaca cacacacaca cacacacaca cacacacaca cacacacaca cacaaatact 613380 aatacactac gtgccagata ctggggtggt gggctgggac caaggaatga agtaatgcat 613440 gtgccagagg gttgaacttt ttaaaaggag taaaaaagta aatctttaca gtagcagctg 613500 gtgggtagga ggtattgagt ccatagaact gctcttagat tggaagggca tgggaaaatg 613560 aagttccatt atgtgatagg gttttacaca cacacacaca cacacacaca cacaaatgtg 613620 agaaagtcac tcaactataa gcattcaaaa aagacagaca tctttcttgt ctttgtgggt 613680 cctgtactta gctcagctca tagaagccac aggaggaacc taataaatgt tagttgatca 613740 tttactgatt taccaataac caattcatgc ctgctctagt gctgtggtct gaatgtgtcc 613800 cccaaaattc atgttgaaag cctaacctcc aaggtgatag tattaagagg tggggccttt 613860 gggaagcttt gccatcatta atggaattaa tgcctctata aaagaggccc tatagagccc 613920 cgtctactct tctactacat gaggtaatgg tgaaaagaca gctagctatc tatgaacaag 613980 ggaagagggc cctcactaag atgtcaaatt tgttggtacc ttgatcttgg acttctcagc 614040 ccccagaacc gtgagaaata aacttctgtt gtttataagc catgctgtct gtggtgtttt 614100 gtaatagcag ccagaacaga ctaagacatc tagtaacaca ttctctggta aacactagga 614160 attcctggcc ttaaaaagtt catagctaat gagaaaagaa ataaacaaca taaaggataa 614220 catgctgtag tccactacat acaaggtgct tccagaccat tcagaaaaac tggataggaa 614280 gatttctaag gtaatactta ttgagtgcct acgtgttagg cgttttacat actttaagcc 614340 tcacaactct ggggaagttt caccaaccca ttttacagat gacaaaactg tggcttacca 614400 agattaataa ggccagaatt aaaattaggg tctaattcca aagatattac cactatacat 614460 accaagatgt cttgttacta cattttatcc ttacatttgg cagtgagggg aaaactcaaa 614520 aagcagtcaa aaaacttttg tcctgaacca acataaaaag agcacctaag acttcatcca 614580 gtattttacc gaaagatcac ttctaaaagt ttgtcttcac cccgatctaa aaattagaaa 614640 actaattttc tttcagcagc tgcatatgta cataatgtaa tgtttctaca tttagaccta 614700 cacaattata agtctaaaca aaatatgtgt aacatgattg gagaacataa ctagcagtca 614760 tttaagaaaa tggacatttg gaaacatcat ttcaagagct tgggatgaaa aattttgcta 614820 tgacctataa atctggatca ttccactgac tgacactgag agaaacagtg tattatcaca 614880 gtttacacag taaatttttt tggaggggag agggaggaga ttgaaataga aatgatcgaa 614940 atagaaatta tctaaagttt aagaaataca actgattaaa tgttacatgt caaagacact 615000 gtaggtaccc aataaatcct gttaaatgga ctgcacaagt gggatgagaa cacgttttcc 615060 ccacacctct gactagtatg tacctttctt aggaagttat tttttcagcc atgggaaaaa 615120 aaagggcaga atttaggaca gataaaacat aagtagctta taaatcctct gaaaggaaat 615180 caaaacacag tattttgtat ctctgtataa agttaagctc ctcagggaca ggggcaatgt 615240 ccagaggata gtgagcatac tacttagcaa actaatgcag gttaataaat attgacacag 615300 taagactagc atagtttaca ttctaatttt gtaaagatta taagttacct cttcatattc 615360 tgttctttta tttctcctgt gtatattata aatacacaaa gattgaaaat tatttcttga 615420 agctatttcc ttttttattt tttggtcaac tgtattagtg tttcttaaaa gggcttctgg 615480 tcatccttag ggcttatcag tagcatcatt aataatgtat tcatttcact aaaaatgtgg 615540 taagtagctt ggatttaaaa acaggatcta atttcaaagc tatttccact atacacacca 615600 agttacaact ttcttatctc tcctaaattc taaattttac atgatttacc aaatcacttc 615660 ttaagtaaga gtacttattg atcagaagtg tgagacaaac accttatccc acttgtccaa 615720 tttattcaac aagattgatt gggtaccttt gtgtctctga caggtaactt tcaacagttg 615780 tatttcttaa actttaggtc gtctcccaaa aaaaactgta ataatttgct gcttctctca 615840 atattgcagg cagtaaaatg atccaaaatt acgggtcata tccacatttc ttcatgattg 615900 aggttaactg tgcactgtaa accccatatg ctattagttt acattttcaa cagcaccctc 615960 gccacttaat aatctcaaac agattttgga ctgttactaa tttagcatat ccataaaaag 616020 tcatttaaaa aatgtagacg ctaaattctc tttcaaggtt gccaagcttc accagtgtct 616080 gtattaaaat tatttctaaa attttacgga ctaaggcatt tggtacattc aattctacct 616140 ttaccaacaa aagcctttac caccaagatg aggaaagcat ccttttcatt ttctacactg 616200 aaaagggggg ggaaaaaagg ccaactgctt gcatacaggt ctgcatataa cacagcagtc 616260 tctggcaaag ccaataactc acgttcaact tcagaaatcc tggtggccgg taacacagag 616320 taacctgtgc gcacaaccct tgggcttgac ataccacttc atccgccctc ccttcccatc 616380 aatccacccc caaaacccca acccaccaag cacacggcta aatatgtctt ccccaagaga 616440 gccaaaaacc ttgaaaacgc cgagaaaggg ctcccctttg aaggaaaggg cctgcccttc 616500 cctgtctggg gccccggctg gctcgaagag cctggctcct aggaggccca aatctcgacg 616560 cctcgcacgt cccgccccgc cccgggcccg ctcgcgtccc ctcgggcgac aaaaccctcc 616620 cgccgtcgct cagccaggac tgacagttac ggctgcagca gccgcggcca ccaggggcct 616680 acttctggca ccagcccctt cggaccacgc gcccccaaac actcgcctcg gcggcggggg 616740 gcggggaagg ggggtgtcga cctcgccaca gcgggccccg aaggccggcc gagtgacgga 616800 ggggagccag cgccgcctgg cgcaggccgc ggcaacactg acctgtcgtc gcccccgcgc 616860 ctgggctgcg gcggccgcct cactggtcgt agtcgccctc gcccgccgcc tccgcccgcc 616920 accgcctcgt tctctttcgc tgccgccacc gccggggctc atgcgggacc cgcgcttcct 616980 tatccggaaa acgaggccgg gaaagggagc gccggggccg ccgaaatccc ggcgttcgtc 617040 gccagccgcc gctgcctgtc cacaccgggg ggctgagggg ccctcctgcc aggggctaca 617100 ggccgcgagc tattccgagg aggagccgaa ggaggcgccg ccgcccgcag ccgagcgcgc 617160 cgggtcggca gaggtgaagc gtaagtaggc ggcggatggc gggcgcccgc gctggcggat 617220 ggctacgcgg cggaggggtg cgcgagcgag cgaagcctgg tgtgtcgggt cctggcgaag 617280 ggaaaaggcc ccgtcgtctc ctgtagtcac cccgagccca gcgccaccat cttgggagac 617340 acacggatct cgcggccgcg gcgcaagacg ggaggactgg ctgggcgggc cgagtatccc 617400 ggcaggcagc gcgcgccgcc cggccgggcg agggctccag gccgggacgc ggggacgtgg 617460 ggcggggcca agacgcgcgg gagggcgccg cgctccgccc ctccttcctt cgccggcccc 617520 gcctccctcc cgcttgccgt cgccgccggc gcacgggcca ttgggaagag gaggtggcct 617580 gcggcccctc ggagtcccac caggctcggt cgccatcttg cgactggaca gaaagggtaa 617640 tccctctttt tagtttctgc tgtctgtgac ccgaaagaat aaacctggga cttccggaag 617700 ccctctgggc accccccccc ccaggagggt tgcagagccc cttggtgtac ccagcagagg 617760 aacgcctcag actttgttgg gaaacgaatg gctctgaaag ttagctgaag ccgctggaat 617820 agccccccag ccccgaggcg gggcaggtgc ctgccgttat tggcttttcg accccaaccc 617880 ttttctatct ggagctgcct ttgtagatgt tgcaggggtg ccccgagagt gcaggccaga 617940 ttttagagga ccaaggtcat ctacttaggc ctcttgccaa cacaggatgt gtcaactagt 618000 ttaccagaga cgaaggtaaa gtcccgtctc ctgcagttgt tgacgttcag taggtcgtcg 618060 gttaagaaaa gtggctccct ggttgacccc agctggatag aggctaattt tgatccatat 618120 gacagctgaa cgtagttaaa gccattaaaa ttaaatccat ttaaagtcat atttggtacc 618180 agggtcacca ttttaaaagg tgtgtgtgtg tatgtgtgtg tgtgtgtgtg tgtgtgtgta 618240 tagctttaca acacttgcta gcaaagccaa aagagtatca ctaacaattc atagtgttac 618300 aacttgcaac tttgttgata agcccttgaa gtactagatg agtacccatg tctagtattc 618360 agatttttta tatcaacagt cgtacatagc agtgtatctt ttttaaattt atttttattt 618420 ttaaacttag aaatggtgtc ttgctatgtt aggcccaggc tggtctcgag ctcctggcct 618480 caagtgatcc tcccacctcg gcctcccaaa gttttgggac tacaggcatg agccacagtg 618540 ctcggccagc agtgtaattt ttaactgtca gtctcggaac atcttttttg tatagccaag 618600 tgtgtgggtg tgtgtgtgta tccgcctcac aactataacc aaccattgaa aaaccaacaa 618660 taagctagaa gaatttaagt tattccagga caactgatga taatgatagt attaagccat 618720 attcgatttt aagatgtttt aactcagctc tttactcact tttcatttcc tctcattaca 618780 catccacatt tggaaactat ttgctgttat atttcatgga aaggactagt aagaattata 618840 atctttaaaa aaatttatct tcgcaagttt tcaaaatagg caacaaagaa tgtaaatctt 618900 taaggacttt attgttggac taattaaagc ataccatttc tactatatct agcatatgga 618960 gatacttata ggtattcttc cttttaagta gaaattgaca ataaattaag tgtaatttta 619020 taatggcctg gtgtatcaaa gtgtggcgga aatccctgag ttccaaaaag attaaagacc 619080 gaagggaaat aagtctgctt ttagctagat gtcagaatga ctattcattg ctttactgag 619140 atcaaggagg atcttaattc ctcctggaga aattacgtat atccgtttta gttcattaat 619200 tttaaatctg tattcttatg tgtgacatta gtattagaat tctttcaaga tttcactgtg 619260 ctttttgttt tatccatttt caaatttaga aatgtttgct catcaaactt accaacataa 619320 atactttcag gaatccttaa gatactagca gtgttccact tccctataca cctgtttata 619380 tg 619382 <210> 2 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Primer <400> 2 ctcccccagt tctggaatga 20 <210> 3 <211> 23 <212> DNA <213> Artificial sequence <220> <223> Primer <400> 3 tacacaggga tttgagcctg cta 23 <210> 4 <211> 26 <212> DNA <213> Artificial sequence <220> <223> Probe <400> 4 cccacagatc aagcattccc caaaga 26 <210> 5 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Primer <400> 5 gcccgaagtg cctattcctt 20 <210> 6 <211> 24 <212> DNA <213> Artificial sequence <220> <223> Primer <400> 6 tggtcaggag aacataggca taaa 24 <210> 7 <211> 26 <212> DNA <213> Artificial sequence <220> <223> Probe <400> 7 actcccaggg ttgatgggct acatcc 26 <210> 8 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Primer <400> 8 caccctgatg tcaccgaatg 20 <210> 9 <211> 23 <212> DNA <213> Artificial sequence <220> <223> Primer <400> 9 gcgttctatt agatgctttg cag 23 <210> 10 <211> 30 <212> DNA <213> Artificial sequence <220> <223> Probe <400> 10 actgaggttc tcctgatctt ttacaagctg 30 <210> 11 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Primer <400> 11 ggcaaattca acggcacagt 20 <210> 12 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Primer <400> 12 gggtctcgct cctggaagat 20 <210> 13 <211> 27 <212> DNA <213> Artificial sequence <220> <223> Probe <400> 13 aaggccgaga atgggaagct tgtcatc 27 <210> 14 <211> 22 <212> DNA <213> Artificial sequence <220> <223> Primer <400> 14 tccttcccta ccttagtctt ga 22 <210> 15 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Primer <400> 15 ccctcttgaa ccaggaaaca 20 <210> 16 <211> 25 <212> DNA <213> Artificial sequence <220> <223> Probe <400> 16 agatggcagc ccacatttct actgt 25 <210> 17 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 17 atgttgcttg cactccatca 20 <210> 18 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 18 acaacataag gtcttattgt 20 <210> 19 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 19 ttttcaactc cagaattttc 20 <210> 20 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 20 ttcagtctta tacagaaatg 20 <210> 21 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 21 ggactgacac agaaaactgg 20 <210> 22 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 22 agggtagaag actagcatac 20 <210> 23 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 23 ggccattcat tcagccacac 20 <210> 24 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 24 taaagatttt atgaaaatac 20 <210> 25 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 25 tttagaacat gtgaatttca 20 <210> 26 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 26 agacatatca cagttgcttg 20 <210> 27 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 27 aatataatgt agtatgacca 20 <210> 28 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 28 gaggacactg gcacatctat 20 <210> 29 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 29 ttaaataata aaatatattt 20 <210> 30 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 30 attggagcaa aaagggatca 20 <210> 31 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 31 aattattccc tatatcctgt 20 <210> 32 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 32 caactgttac caagacttca 20 <210> 33 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 33 atctgcgaat agaggccctc 20 <210> 34 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 34 aaggttttta tttcatcact 20 <210> 35 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 35 gcccatggat ggttgtcaaa 20 <210> 36 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 36 taggttgcat aaagccaggc 20 <210> 37 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 37 cacacatctt gttccctcaa 20 <210> 38 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 38 tttttttaat cctctgatga 20 <210> 39 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 39 agtctctttt ctttcggtgc 20 <210> 40 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 40 ggaaagttct tctctctcct 20 <210> 41 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 41 atttggtcta aagtgaagtt 20 <210> 42 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 42 ttttgtgaga tttttgaata 20 <210> 43 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 43 tgttaaatgc ttttctaaat 20 <210> 44 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 44 ctgatgattg attgtttcct 20 <210> 45 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 45 tatgataatg tgtagttttt 20 <210> 46 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 46 aagggtaata cggacctcat 20 <210> 47 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 47 ctattttttg cttcccttat 20 <210> 48 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 48 gaattcttag aaagttaatt 20 <210> 49 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 49 tgccatcttc aagactaagg 20 <210> 50 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 50 aatggaaaag atgtatcacg 20 <210> 51 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 51 aactttggca gctattcaat 20 <210> 52 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 52 gacactaggt tttgcaaaag 20 <210> 53 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 53 tatgaatttt caattcaatg 20 <210> 54 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 54 cacttaaggg aactttcaga 20 <210> 55 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 55 gagatgatgt taagctttca 20 <210> 56 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 56 taagacaagt ggccatgaag 20 <210> 57 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 57 ctctgttctg tctcaaaaca 20 <210> 58 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 58 tataagaaag aagattacag 20 <210> 59 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 59 aaatgttaat agactgcgat 20 <210> 60 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 60 ttaaactccc cagtcaaaag 20 <210> 61 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 61 atttacttca aacaggagct 20 <210> 62 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 62 tcaggaaatt aaagcattca 20 <210> 63 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 63 cctaacctgg atctcagata 20 <210> 64 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 64 tacagcaacc ctagaaaact 20 <210> 65 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 65 atctttggca gatgtaacct 20 <210> 66 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 66 gagtattatc caaaagaaca 20 <210> 67 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 67 aaagcccagg attaggcagc 20 <210> 68 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 68 ctacaaagag tgaatcatga 20 <210> 69 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 69 taatcttaag tttaagtgga 20 <210> 70 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 70 aaaaagacat agaatgacag 20 <210> 71 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 71 agatacaaat ttaaaaaagt 20 <210> 72 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 72 ggtagcccca atacagattc 20 <210> 73 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 73 cttcaacagc agacttgatc 20 <210> 74 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 74 ggtccacaca gagttcaaat 20 <210> 75 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 75 ctttgggaca tcccaaagtt 20 <210> 76 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 76 tacacatctt gtatacaagg 20 <210> 77 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 77 taatactttc ttgagtaata 20 <210> 78 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 78 gggtggttgg attgctttat 20 <210> 79 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 79 ctgcacactg tacaggaggg 20 <210> 80 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 80 ttgattcact gcacactgta 20 <210> 81 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 81 gtgcaggaag gaggttttgt 20 <210> 82 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 82 atacagtata tacatcatcc 20 <210> 83 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 83 aagtttaaaa caaaaaaagg 20 <210> 84 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 84 aatgtctgtt ctttgtggta 20 <210> 85 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 85 atacctgctt ttgtgacaat 20 <210> 86 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 86 gagtgtagct catttcagaa 20 <210> 87 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 87 tttctcaatg tcaactctca 20 <210> 88 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 88 caagccgaat cttgacatac 20 <210> 89 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 89 gaccagaaaa gctacatagc 20 <210> 90 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 90 attttgtata ttgtagcttt 20 <210> 91 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 91 ccatctttct gttatcttgt 20 <210> 92 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 92 ctttgtttct ttttaagaaa 20 <210> 93 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 93 accttgacaa caccctagct 20 <210> 94 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 94 aaaaaggaac cataaactaa 20 <210> 95 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 95 ggtgtgtcag ctgtgctggt 20 <210> 96 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 96 atcatacctt cacttttttt 20 <210> 97 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 97 ttcattgagc ttcctggata 20 <210> 98 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 98 ttacttcttt ttcattaagt 20 <210> 99 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 99 agtaaacact ccaacaaaaa 20 <210> 100 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 100 ggtctaagca aaatgtgaag 20 <210> 101 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 101 cagttaggcc tgctccgaat 20 <210> 102 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 102 actctgaaaa tagccaattt 20 <210> 103 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 103 agtatctatc tacaattaaa 20 <210> 104 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 104 aatggcttag ctactcaccc 20 <210> 105 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 105 cctctctgca aaacaagaga 20 <210> 106 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 106 attactcatt ctgggaatgc 20 <210> 107 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 107 gttttcagca tgattctaac 20 <210> 108 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 108 catatataaa aattagaatg 20 <210> 109 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 109 aatgccacaa agctggctgt 20 <210> 110 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 110 gtgcacagat aatgactaga 20 <210> 111 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 111 cagtgagaag tcaattgtca 20 <210> 112 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 112 tcctttagca tttctattag 20 <210> 113 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 113 aacatgtgct tgcaagccat 20 <210> 114 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 114 aaataactgg atctcataac 20 <210> 115 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 115 cttaggagag aaacactttc 20 <210> 116 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 116 tacatcctgt aggctttctt 20 <210> 117 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 117 actgagaaat ctcttgaatg 20 <210> 118 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 118 ttgctctttt tactttgttc 20 <210> 119 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 119 actctaagtt ttattaatag 20 <210> 120 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 120 tttggaagag cttaataaag 20 <210> 121 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 121 tagctagaat ttcaactact 20 <210> 122 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 122 atgtagtatt tatttcattt 20 <210> 123 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 123 gcctaatatg tgtcatcctg 20 <210> 124 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 124 cctcaattct atggttagtt 20 <210> 125 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 125 tcttggagat gacttctctg 20 <210> 126 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 126 tcttcaagac taaggtaggg 20 <210> 127 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 127 agtaaggtct gttattctcc 20 <210> 128 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 128 gctatacaac aaaaagaatt 20 <210> 129 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 129 actgtggaaa aactttggca 20 <210> 130 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 130 ataatctaca tgtatagacc 20 <210> 131 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 131 aaaagccaat tctgaaattc 20 <210> 132 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 132 attctcctac ctctcagcct 20 <210> 133 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 133 aactgtagca aatatactac 20 <210> 134 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 134 aaattactgc tctgtaaaag 20 <210> 135 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 135 gattcaatga aataaaaaat 20 <210> 136 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 136 aatgacatag cttatgctgt 20 <210> 137 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 137 ctagaaatta agacatccct 20 <210> 138 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 138 gccacaccat caaaagaacc 20 <210> 139 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 139 tggaccacct aagacctcaa 20 <210> 140 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 140 accggttccc aattttctcc 20 <210> 141 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 141 gagagaatac ggccctgatg 20 <210> 142 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 142 aacttcaatc agagtaatat 20 <210> 143 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 143 ggcaaaggaa tgaagagacc 20 <210> 144 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 144 gccaataaca agaaaagaga 20 <210> 145 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 145 atcaaattgg atgacctaaa 20 <210> 146 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 146 caatggattt caattacact 20 <210> 147 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 147 attctccaac aaaaagacat 20 <210> 148 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 148 gtagctacaa gaagtaattg 20 <210> 149 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 149 aaagaatgcc tataagaatt 20 <210> 150 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 150 ctactggcat cagtcaaaac 20 <210> 151 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 151 aaaaggcaag gctaaggagt 20 <210> 152 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 152 cccacacagg tcattcattc 20 <210> 153 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 153 tgtatacacc atcccagaaa 20 <210> 154 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 154 aaaatgccag tttgttgtac 20 <210> 155 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 155 acactgtaca ggagggtgtc 20 <210> 156 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 156 ttcactgcac actgtacagg 20 <210> 157 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 157 aaatgatgtt gattcactgc 20 <210> 158 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 158 agagttttca tgaattcagg 20 <210> 159 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 159 ggtttctttc attaaatagc 20 <210> 160 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 160 gaggcaactc ctgagagctg 20 <210> 161 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 161 ttaaatgtca ggaggtcccc 20 <210> 162 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 162 tgtcatctga tctcacacat 20 <210> 163 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 163 caaagtccaa gggaaatgat 20 <210> 164 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 164 cacagtagag gcaaatgaga 20 <210> 165 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 165 gacatttagg atgatgatat 20 <210> 166 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 166 gttgtattaa tggacttttg 20 <210> 167 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 167 attttttgca taagtgcatt 20 <210> 168 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 168 acatttctta gttgaacagt 20 <210> 169 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 169 agattcttcc ccaatcccat 20 <210> 170 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 170 ctcacttgtc tccttttacc 20 <210> 171 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 171 acaataagga agagcaaaac 20 <210> 172 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 172 atcatgtgca tacccagggt 20 <210> 173 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 173 tcactcattt tgttcagctt 20 <210> 174 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 174 gttttcactc attttgttca 20 <210> 175 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 175 acaattattc tcatcatcga 20 <210> 176 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 176 cctcagcatc ctcagacaat 20 <210> 177 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 177 tctggaatga gtccctcagc 20 <210> 178 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 178 ctcagattga catctggaat 20 <210> 179 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 179 cactcatttt gttcagcttt 20 <210> 180 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 180 agttttcact cattttgttc 20 <210> 181 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 181 gtcatcacct ctcttcagga 20 <210> 182 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 182 aagtcatcac ctctcttcag 20 <210> 183 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 183 ttaagtcatc acctctcttc 20 <210> 184 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 184 ttttaagtca tcacctctct 20 <210> 185 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 185 atttttaagt catcacctct 20 <210> 186 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 186 tgatttttaa gtcatcacct 20 <210> 187 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 187 catgattttt aagtcatcac 20 <210> 188 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 188 agcatgattt ttaagtcatc 20 <210> 189 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 189 tgagcatgat ttttaagtca 20 <210> 190 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 190 attgagcatg atttttaagt 20 <210> 191 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 191 ctattgagca tgatttttaa 20 <210> 192 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 192 tcctattgag catgattttt 20 <210> 193 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 193 aatcctattg agcatgattt 20 <210> 194 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 194 gtaatcctat tgagcatgat 20 <210> 195 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 195 gcgtaatcct attgagcatg 20 <210> 196 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 196 cagcgtaatc ctattgagca 20 <210> 197 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 197 ctcagcgtaa tcctattgag 20 <210> 198 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 198 gcctcagcgt aatcctattg 20 <210> 199 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 199 gggcctcagc gtaatcctat 20 <210> 200 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 200 ctgggcctca gcgtaatcct 20 <210> 201 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 201 ggctgggcct cagcgtaatc 20 <210> 202 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 202 taggctgggc ctcagcgtaa 20 <210> 203 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 203 cctaggctgg gcctcagcgt 20 <210> 204 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 204 cacctaggct gggcctcagc 20 <210> 205 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 205 ctcacctagg ctgggcctca 20 <210> 206 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 206 ttctcaccta ggctgggcct 20 <210> 207 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 207 aattctcacc taggctgggc 20 <210> 208 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 208 aaaattctca cctaggctgg 20 <210> 209 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 209 ccaaaattct cacctaggct 20 <210> 210 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 210 cttccaaaat tctcacctag 20 <210> 211 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 211 cctcttccaa aattctcacc 20 <210> 212 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 212 catcctcttc caaaattctc 20 <210> 213 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 213 cagcatcctc ttccaaaatt 20 <210> 214 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 214 tcccagcatc ctcttccaaa 20 <210> 215 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 215 ggatcccagc atcctcttcc 20 <210> 216 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 216 gccacccaca tgccctgccc 20 <210> 217 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 217 agagctcact gaaagacaca 20 <210> 218 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 218 gaagagctca ctgaaagaca 20 <210> 219 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 219 gcaggatcca ctcacctatg 20 <210> 220 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 220 cagagctcag ccttgaccca 20 <210> 221 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 221 agctcagtgc aggagaccag 20 <210> 222 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 222 ccacagctca gtgcaggaga 20 <210> 223 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 223 gatgtgctca ccacagctca 20 <210> 224 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 224 ggaacccttt cctgcctgga 20 <210> 225 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 225 caatataagg ttctcatcat 20 <210> 226 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 226 tcaggacaat ataaggttct 20 <210> 227 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 227 catcacctct cttcaggaca 20 <210> 228 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 228 tctcacctag gctaggcctc 20 <210> 229 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 229 agctcactga aagacacaag 20 <210> 230 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 230 aggaagggcc tgagcttcag 20 <210> 231 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 231 ctcaccacac ctcagtgcag 20 <210> 232 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 232 ctttcctgcc tggaccacca 20 <210> 233 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 233 ttgggcaccc tccagatgcc 20 <210> 234 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 234 cactcaccta tgctggtcaa 20 <210> 235 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 235 tcagctgggt gctgccctgc 20 <210> 236 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 236 ccattcaggg ccatgggttt 20 <210> 237 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 237 tccctgcaca tgcatccagc 20 <210> 238 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 238 actccaggga ccaagagctc 20 <210> 239 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 239 gagacccact gagatggccc 20 <210> 240 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 240 accccatgac cctggaggtg 20 <210> 241 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 241 atgaccccag caggatgcac 20 <210> 242 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 242 tcacccacca ctgtccagag 20 <210> 243 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 243 gtaccactga gatggcccat 20 <210> 244 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 244 aatgcagacc tggcagtcgc 20 <210> 245 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 245 cttcaactaa cagtatctta 20 <210> 246 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 246 agtcttcaac taacagtatc 20 <210> 247 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 247 ctatttcatt aagtcacccc 20 <210> 248 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 248 ggacagctgt gtggagggat 20 <210> 249 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 249 accaccaggg agaccagcct 20 <210> 250 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 250 cagcctttct accaccaggg 20 <210> 251 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 251 tcagcctttc taccaccagg 20 <210> 252 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 252 acagagtgtt tactgtgagc 20 <210> 253 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 253 tccatggaat ggctgtcatg 20 <210> 254 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 254 ttccttcaga gttatttctt 20 <210> 255 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 255 ttattctcct tccttcagag 20 <210> 256 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 256 gttattctcc ttccttcaga 20 <210> 257 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 257 gaagtagtcc tgccctttcc 20 <210> 258 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 258 atatcctttc ctctcctact 20 <210> 259 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 259 gactgatggt tacccataca 20 <210> 260 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 260 catttaacaa ctattatctt 20 <210> 261 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 261 tcattaaata gctaaccatt 20 <210> 262 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 262 ccactttgca actcaagatt 20 <210> 263 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 263 cagccacttt gcaactcaag 20 <210> 264 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 264 gactccagcc actttgcaac 20 <210> 265 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 265 ccagaaattt agtctgttgt 20 <210> 266 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 266 cataagctgc tggatttgtt 20 <210> 267 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 267 gaagagaacg aggatataaa 20 <210> 268 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 268 gtgatatatt agaactgtat 20 <210> 269 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 269 agaggattta gagttaaaat 20 <210> 270 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 270 actgaaaggt ctgtatgttt 20 <210> 271 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 271 caggcctagc ttccacctaa 20 <210> 272 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 272 tctgtcaaag acctgtgagg 20 <210> 273 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 273 tctgcttgtg gttcttccct 20 <210> 274 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 274 caaatatgga atagcacttg 20 <210> 275 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 275 gttgagaacg gtattgagta 20 <210> 276 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 276 ctcttgtttt cagttgagaa 20 <210> 277 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 277 atttctccat ggactccaga 20 <210> 278 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 278 cattggcttc atatttctcc 20 <210> 279 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 279 tattgccttc actgctgcct 20 <210> 280 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 280 actgacttgc tctgcctact 20 <210> 281 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 281 gagaagtctc tcatggcacc 20 <210> 282 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 282 ggagtgctcc acacttctgt 20 <210> 283 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 283 ctccaggttg tggaggttgt 20 <210> 284 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 284 gtatatactc caggttgtgg 20 <210> 285 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 285 acttctcatt ctctccacca 20 <210> 286 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 286 aaagcatttt ctaccagagc 20 <210> 287 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 287 tagacaagga aagcattttc 20 <210> 288 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 288 cacctgccct gcttttgctt 20 <210> 289 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 289 tggtcctagc ttcacctgcc 20 <210> 290 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 290 agatccaacc tgtgtggaaa 20 <210> 291 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 291 agaaattaga gccaggttcc 20 <210> 292 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 292 tccccccaga aggcttgact 20 <210> 293 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 293 tcgctggcca tttcatatat 20 <210> 294 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 294 aaaacatgtt aactgttatc 20 <210> 295 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 295 ttagccatgt gctttgtgac 20 <210> 296 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 296 tcccttctgt catctgatct 20 <210> 297 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 297 aaggtagttc tcccttctgt 20 <210> 298 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 298 ttccattgca ctcctttcta 20 <210> 299 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 299 taaaaggaaa acccacttgt 20 <210> 300 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 300 tacagaaatt accagtaaag 20 <210> 301 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 301 tccagatttc tacagaaatt 20 <210> 302 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 302 tcactgcaca ctgtacagga 20 <210> 303 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 303 tgcctagttc cctcctgaaa 20 <210> 304 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 304 ttatgtttac ttcatgactg 20 <210> 305 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 305 cttcattatt ctctagtgcc 20 <210> 306 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 306 ctattcccct tcaacatgtg 20 <210> 307 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 307 catacccaac atgcttgcat 20 <210> 308 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 308 aatgcattac cctacaatgc 20 <210> 309 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 309 ctcatcacaa ctgggtggta 20 <210> 310 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 310 atcccagctc atcacaactg 20 <210> 311 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 311 tccaagtgct tcaagctgag 20 <210> 312 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 312 cacccacagc aggcagataa 20 <210> 313 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 313 taccttgctc caaaataatc 20 <210> 314 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 314 ctgtttcttg aggcaaatga 20 <210> 315 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 315 cttttctcaa tgtcaactct 20 <210> 316 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 316 agagttatac acggaaccca 20 <210> 317 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 317 ttctagggct ccagtttatg 20 <210> 318 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 318 tggtcatctc gggtatataa 20 <210> 319 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 319 cttactatct tcaagaattc 20 <210> 320 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 320 tttttcttac tatcttcaag 20 <210> 321 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 321 agtcaattgt cagacttatt 20 <210> 322 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 322 aaggagttcc tttagcattt 20 <210> 323 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 323 cagaccgaag gagttccttt 20 <210> 324 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 324 tccagtgcct ttctatttca 20 <210> 325 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 325 actttgtttt aaacttacac 20 <210> 326 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 326 catcaacaca agtttataat 20 <210> 327 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 327 aactcccaca aggtactctt 20 <210> 328 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 328 actgtcaact cctgaactcc 20 <210> 329 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 329 caatgaatct attcttagat 20 <210> 330 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 330 gtgaaactgt ttataccctt 20 <210> 331 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 331 gttggtgatg caggtaaagt 20 <210> 332 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 332 ttgttactga gctgtgccac 20 <210> 333 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 333 aagtggatct cttgggcagg 20 <210> 334 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 334 tttaccctct cccaaccact 20 <210> 335 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 335 ggctgctgtt tgagtcccca 20 <210> 336 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 336 atgggctgct gtttgagtcc 20 <210> 337 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 337 tatgggctgc tgtttgagtc 20 <210> 338 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 338 aaagccaggc caggtgctga 20 <210> 339 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 339 cataaagcca ggccaggtgc 20 <210> 340 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 340 tgcataaagc caggccaggt 20 <210> 341 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 341 ggttgcataa agccaggcca 20 <210> 342 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 342 tctaggttgc ataaagccag 20 <210> 343 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 343 ttctctaggt tgcataaagc 20 <210> 344 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 344 ccttctctag gttgcataaa 20 <210> 345 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 345 tcaccttctc taggttgcat 20 <210> 346 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 346 tatcaccttc tctaggttgc 20 <210> 347 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 347 cacatcttgt tccctcaagg 20 <210> 348 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 348 ttcacacatc ttgttccctc 20 <210> 349 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 349 tgcttcacac atcttgttcc 20 <210> 350 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 350 cctgcttcac acatcttgtt 20 <210> 351 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 351 gaacctgctt cacacatctt 20 <210> 352 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 352 ctttcatcag ttagtcaggt 20 <210> 353 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 353 ggagttggtt attggaaaat 20 <210> 354 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 354 tctattggtg ttccttttag 20 <210> 355 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 355 agagtagtct attggtgttc 20 <210> 356 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 356 cttttaagat aatttttctc 20 <210> 357 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 357 tacgctcctt catttcatgc 20 <210> 358 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 358 tttttaatcc tctgatgaat 20 <210> 359 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 359 ctctcttctc ctttatgact 20 <210> 360 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 360 cttaaataag ttttctaccc 20 <210> 361 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 361 agccattatt tcttaaataa 20 <210> 362 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 362 catatctttt cctagatttg 20 <210> 363 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 363 agaatcctgt ctccctctta 20 <210> 364 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 364 tgagtctctt ttctttcggt 20 <210> 365 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 365 tgatgagtct cttttctttc 20 <210> 366 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 366 tgtgatgagt ctcttttctt 20 <210> 367 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 367 tactgagaaa tctcttgaat 20 <210> 368 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 368 taaaattatt tatacaccat 20 <210> 369 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 369 tttatactgt agtatgcatt 20 <210> 370 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 370 ttacttccct acccttgcat 20 <210> 371 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 371 cttttacttc cctacccttg 20 <210> 372 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 372 atttatttta agctgataac 20 <210> 373 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 373 aaatccattt gtccagtctg 20 <210> 374 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 374 tatctgcatg caatatcttt 20 <210> 375 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 375 ctgtaagtat agatgcctct 20 <210> 376 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 376 ttagcctttt gatatagttt 20 <210> 377 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 377 gcttcaccat tttgaccttc 20 <210> 378 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 378 ttttgaaagg gaggcactga 20 <210> 379 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 379 tgaggtgtaa tgttgtttat 20 <210> 380 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 380 taatagtctc tattgttttt 20 <210> 381 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 381 caagttaact aatatgttgg 20 <210> 382 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 382 tattgattca attcccttat 20 <210> 383 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 383 gaatattgat tcaattccct 20 <210> 384 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 384 aattttttta aatggttggc 20 <210> 385 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 385 aacagagaat tgtatatcca 20 <210> 386 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 386 acatgagatc tttaataaga 20 <210> 387 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 387 caagagagaa gccactcatg 20 <210> 388 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 388 agcagatttg agctggaaga 20 <210> 389 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 389 aactggcaga aaatatctct 20 <210> 390 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 390 aaagaagaac ataaactggc 20 <210> 391 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 391 gttggctcta ttttcaaatg 20 <210> 392 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 392 ctgtttaggc tggacactgt 20 <210> 393 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 393 attcaggaaa ttaaagcatt 20 <210> 394 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 394 agcagaacag accttatttg 20 <210> 395 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 395 ccttcaacca gaggagcaga 20 <210> 396 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 396 gatcttggtt tgtagaaggt 20 <210> 397 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 397 ttcaaaatgg tagaaaattg 20 <210> 398 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 398 tgaaaggcct acagcaacca 20 <210> 399 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 399 atgggagctc tggaaaacag 20 <210> 400 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 400 ttctgagtat atgtgaaaca 20 <210> 401 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 401 ataaggagat taatttaaga 20 <210> 402 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 402 gaatcaaaga aagaaggaat 20 <210> 403 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 403 gctgtaataa taatcatatt 20 <210> 404 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 404 agaattcttc cctacaggtt 20 <210> 405 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 405 cagtaattaa tgttcttata 20 <210> 406 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 406 ccccaattca gtaattaatg 20 <210> 407 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 407 ggccccaatt cagtaattaa 20 <210> 408 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 408 atgtaaccta ttcaagatga 20 <210> 409 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 409 ttatttggaa gaagaatctt 20 <210> 410 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 410 tataaaatac tttttatggg 20 <210> 411 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 411 gactgtgata aagatgtata 20 <210> 412 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 412 taagggtcat gtactataca 20 <210> 413 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 413 gtgtgtgcaa tagcctaaat 20 <210> 414 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 414 cagaagcaaa agatagcagc 20 <210> 415 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 415 tattaatgta cttgaagatg 20 <210> 416 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 416 atcagtgtgt gcagattctg 20 <210> 417 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 417 tcccatcatc agtgtgtgca 20 <210> 418 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 418 tatgaaaatt aatgttcaag 20 <210> 419 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 419 aaaaaatttt aaacccctag 20 <210> 420 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 420 tcatgaaagt agagagtaag 20 <210> 421 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 421 tgaaacaatt taagtgccca 20 <210> 422 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 422 ttgaagggat atcttcattc 20 <210> 423 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 423 tctgaaaaaa atagaacaac 20 <210> 424 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 424 aataaaagac ctgcacagca 20 <210> 425 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 425 caaaataaaa gacctgcaca 20 <210> 426 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 426 agacccttat ttacaccata 20 <210> 427 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 427 ctattaatga gctatctgaa 20 <210> 428 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 428 tctactatta atgagctatc 20 <210> 429 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 429 tttccatcta ctattaatga 20 <210> 430 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 430 gtctccacca gaacaaaact 20 <210> 431 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 431 atgacataac catatacaaa 20 <210> 432 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 432 ttactgatga cataaccata 20 <210> 433 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 433 caaaattcaa cctggtttca 20 <210> 434 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 434 atggagggtg taaatcaaat 20 <210> 435 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 435 tgttacactg ttattaaagc 20 <210> 436 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 436 aaaacaatga agcagaggga 20 <210> 437 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 437 taataaaaag tatcccacca 20 <210> 438 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 438 gaagttatgc accatcaaat 20 <210> 439 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 439 tttactactg atatcaccaa 20 <210> 440 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 440 agaacagact aagcccgaaa 20 <210> 441 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 441 aattctggtg gaaaatacag 20 <210> 442 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 442 acagaaatca tatcaaatcc 20 <210> 443 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 443 atatatgaaa cattccatcc 20 <210> 444 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 444 ttacacttta gaccaaacgg 20 <210> 445 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 445 gggcagattg atcacctaga 20 <210> 446 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 446 cgggacctca atactctact 20 <210> 447 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 447 taaatggaaa ttgagagcag 20 <210> 448 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 448 aagtcacaac cacatactgc 20 <210> 449 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 449 gattctccaa caaaaagaca 20 <210> 450 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 450 gacactagca gtttcttacc 20 <210> 451 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 451 gcttaaagta gcctaaggat 20 <210> 452 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 452 acaataagtt gtagctacaa 20 <210> 453 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 453 ttaaaaacaa ctgtagctac 20 <210> 454 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 454 ttcctattag gaggtttaaa 20 <210> 455 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 455 ataagtaatt catagtcaga 20 <210> 456 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 456 ggcttaaata aaagactgct 20 <210> 457 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 457 taagattcca ttgccagaat 20 <210> 458 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 458 aagtttcgca ataagattcc 20 <210> 459 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 459 tttcagtcag caaaggcagc 20 <210> 460 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 460 tctcaaccct gaaaacaatc 20 <210> 461 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 461 cattggcatt attcacagca 20 <210> 462 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 462 ctgactgtca ttcatataag 20 <210> 463 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 463 tgcataacga taatcatgtg 20 <210> 464 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 464 ttgtagatcc tggcaagtat 20 <210> 465 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 465 aaaaataaag tttccctctt 20 <210> 466 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 466 caaaacttgt caacattata 20 <210> 467 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 467 ctatatttag accaaatgag 20 <210> 468 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 468 ctgacatata taaattagaa 20 <210> 469 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 469 catagcaacc tgacatatat 20 <210> 470 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 470 acaaacattg taaaaacata 20 <210> 471 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 471 ttagaacatg tagccataat 20 <210> 472 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 472 aattgtattt aatttaatga 20 <210> 473 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 473 atcatactgg agccaggtga 20 <210> 474 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 474 aatgcagaaa taagaccttc 20 <210> 475 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 475 cagtcatcct tatctaaggg 20 <210> 476 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 476 aagccaaaga gtactcttcc 20 <210> 477 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 477 gatatctggg tgtgtcagct 20 <210> 478 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 478 caacataagg tcttattgtt 20 <210> 479 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 479 ggtcttctag aagctaatag 20 <210> 480 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 480 ttgataagtg gtcttctaga 20 <210> 481 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 481 caattctttt gagtgtgtac 20 <210> 482 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 482 tcaattcttt tgagtgtgta 20 <210> 483 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 483 gtgtgacatt gtcatcatac 20 <210> 484 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 484 ctttatgctt tctgttcttt 20 <210> 485 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 485 gagactctct ttgtttcttt 20 <210> 486 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 486 ttcattggaa ttcattgagc 20 <210> 487 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 487 caagactttc ttcttgtttt 20 <210> 488 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 488 agtcagctgt taatcttcct 20 <210> 489 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 489 tttttctttg agcattttta 20 <210> 490 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 490 tttaagtatt tagagaactc 20 <210> 491 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 491 tacctaggct cacttgcttt 20 <210> 492 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 492 tagttgttga tttgaataac 20 <210> 493 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 493 tgtagttgtt gatttgaata 20 <210> 494 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 494 ttattttaaa atcacttcag 20 <210> 495 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 495 tcttctttgg caaatatatt 20 <210> 496 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 496 tccctttttg ccatcttttg 20 <210> 497 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 497 aataagtttc taatttacac 20 <210> 498 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 498 tctcatgtgt ttttgttcct 20 <210> 499 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 499 taaacctgga gattttatcc 20 <210> 500 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 500 gggaacacac cattcagcag 20 <210> 501 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 501 aatcttgttg actaaaagta 20 <210> 502 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 502 gtctcacgct gtgtgaatca 20 <210> 503 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 503 aggtctcacg ctgtgtgaat 20 <210> 504 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 504 tgctcctatt tcaatatgag 20 <210> 505 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 505 ataaggttca aaagccggtg 20 <210> 506 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 506 aactggtaac ataaatgcag 20 <210> 507 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 507 tcagagcaaa atggactgac 20 <210> 508 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 508 tacaaatacc cagtctgcag 20 <210> 509 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 509 aaggccctta tcatatgcca 20 <210> 510 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 510 tcctataaaa gaagatattt 20 <210> 511 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 511 ctgtgagagc tctgccctca 20 <210> 512 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 512 gttaatagtg ttcttacatc 20 <210> 513 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 513 cagtggagtc aagttggtta 20 <210> 514 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 514 tctactagct aactttatca 20 <210> 515 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 515 aggatcaaag cagaaattaa 20 <210> 516 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 516 aaaaacatag actttactaa 20 <210> 517 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 517 cacaaaaaac tgattatata 20 <210> 518 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 518 gatctgtgtt gttcttaagt 20 <210> 519 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 519 aaggtagatt ttatggctac 20 <210> 520 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 520 gggcaaaaat agcaacataa 20 <210> 521 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 521 aagacataga tgatcccata 20 <210> 522 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 522 tatgagatgt aaggagacaa 20 <210> 523 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 523 gataggagta atcttttttt 20 <210> 524 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 524 aaacaaaaac tctcctaagt 20 <210> 525 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 525 agaactaaca gaattaagag 20 <210> 526 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 526 cagaactaac agaattaaga 20 <210> 527 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 527 acacagaact aacagaatta 20 <210> 528 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 528 aaaaagagga aaaccgaaag 20 <210> 529 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 529 catacaaatg tcactaatat 20 <210> 530 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 530 aagactagca tacaaatgtc 20 <210> 531 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 531 acaggtgtat attccctatc 20 <210> 532 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 532 atatatctac tgaatatgat 20 <210> 533 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 533 ctcagaaccc tttggtctaa 20 <210> 534 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 534 ctgacttgac tttaatgaaa 20 <210> 535 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 535 gcattcagct tatagcagaa 20 <210> 536 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 536 ctgcattcag cttatagcag 20 <210> 537 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 537 aaacattcct cataccacac 20 <210> 538 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 538 cttatccttg atccagacaa 20 <210> 539 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 539 aatgggaaat gctaaagttg 20 <210> 540 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 540 agtgacacag tagttgtatc 20 <210> 541 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 541 caatttcctc tctaccaagc 20 <210> 542 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 542 ctttgtcatt tcatttataa 20 <210> 543 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 543 atacaggcat ctcagccctc 20 <210> 544 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 544 aaagtaccaa agtggctgct 20 <210> 545 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 545 aaaagtacca aagtggctgc 20 <210> 546 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 546 gaaataatga actcacagtc 20 <210> 547 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 547 cacagttgtt taggtcatct 20 <210> 548 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 548 gcatgccata tttccttctt 20 <210> 549 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 549 atagaggcat gccatatttc 20 <210> 550 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 550 agcaaaaata atcttagaaa 20 <210> 551 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 551 gattccaggc cttctatctc 20 <210> 552 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 552 ggtctcaatg aggaaaagga 20 <210> 553 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 553 ataaaagcaa aagagagtta 20 <210> 554 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 554 tctattctga aaccccaata 20 <210> 555 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 555 gacatgccat caagagaaga 20 <210> 556 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 556 atgtattaac caatattttg 20 <210> 557 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 557 agaacccact tgatctatta 20 <210> 558 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 558 taaagaattg agtaccaaaa 20 <210> 559 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 559 tatcacatta attccctctc 20 <210> 560 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 560 tagaatagaa aagcatgaag 20 <210> 561 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 561 aacaactata tttgcttgta 20 <210> 562 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 562 ataatcacac taaatcttaa 20 <210> 563 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 563 cctctattaa gatctatgag 20 <210> 564 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 564 acttcatcaa tatttcccca 20 <210> 565 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 565 gcacttaaat ttatcagttg 20 <210> 566 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 566 aagcacttaa atttatcagt 20 <210> 567 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 567 ttagtatgtc gagaactcaa 20 <210> 568 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 568 aagttgaaac acattttagc 20 <210> 569 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 569 aggattaaaa gttgaaacac 20 <210> 570 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 570 caggattaaa agttgaaaca 20 <210> 571 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 571 aatcagggaa gcaggattaa 20 <210> 572 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 572 tgattactct tggcagtaat 20 <210> 573 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 573 tgatagatac ttgtattagc 20 <210> 574 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 574 caaatctaaa gctcatttac 20 <210> 575 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 575 ctaccaaaat gtcaaatcta 20 <210> 576 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 576 gtaacctgaa tatttcatga 20 <210> 577 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 577 aaataatggt aacctgaata 20 <210> 578 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 578 aatacattac tgaaataatg 20 <210> 579 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 579 tttaccttga cattctaata 20 <210> 580 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 580 ttaacctatt ttaataatat 20 <210> 581 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 581 ttaagtgatt ggaaataaaa 20 <210> 582 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 582 caattaggaa tatttaagtg 20 <210> 583 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 583 ccaggcaatg gctctttcaa 20 <210> 584 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 584 tgtatagttt acccaggcaa 20 <210> 585 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 585 ctttatcaat ctaatcaatt 20 <210> 586 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 586 actttatagt gtggatggta 20 <210> 587 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 587 ttttagggaa ttgtcctgat 20 <210> 588 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 588 aaggaaacac acataatacc 20 <210> 589 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 589 ggaaggaaac acacataata 20 <210> 590 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 590 cactaaggac aaagatatgg 20 <210> 591 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 591 tatttgttca ttctcaagaa 20 <210> 592 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 592 caacctgggc tctcatctaa 20 <210> 593 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 593 aatgcttgat ctgtgggctc 20 <210> 594 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 594 attgtgtaca cagggatttg 20 <210> 595 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 595 aactgtatac tttgaaagta 20 <210> 596 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 596 gaagcaagta agtaaataat 20 <210> 597 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 597 cttagatgtg tttatccaaa 20 <210> 598 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 598 gtgtttttcc atttttctct 20 <210> 599 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 599 tggctctatc aaggcttccc 20 <210> 600 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 600 aatcctatat tttggctcta 20 <210> 601 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 601 gaactatcct gcatccgagg 20 <210> 602 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 602 caaccatcga gatgatcata 20 <210> 603 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 603 taaatgcttt tctaaatcta 20 <210> 604 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 604 gcttttatag tgttgaggca 20 <210> 605 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 605 ttaagctcta attaaaacag 20 <210> 606 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 606 tatttcactg gagctttgat 20 <210> 607 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 607 aatcatctac tgatgaacac 20 <210> 608 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 608 tctttatcta atcatctact 20 <210> 609 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 609 ttctctttat ctaatcatct 20 <210> 610 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 610 agttcctgga aaccgccatt 20 <210> 611 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 611 atgctgttgt acactagatc 20 <210> 612 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 612 gtacactatt gttttgatat 20 <210> 613 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 613 cacccctaat ttatattact 20 <210> 614 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 614 cataggtcaa ttccttcacc 20 <210> 615 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 615 ttaatttaaa tagtttacaa 20 <210> 616 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 616 ctagcttgaa tggataccaa 20 <210> 617 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 617 tagtggttgc cttagtatta 20 <210> 618 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 618 caagtgctat atttttttaa 20 <210> 619 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 619 tatatataat tgagggccac 20 <210> 620 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 620 ataattataa gatagggttt 20 <210> 621 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 621 attagtattg ctgctctagc 20 <210> 622 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 622 ccaactgtaa tcattgattt 20 <210> 623 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 623 gataatgtgt agttttttat 20 <210> 624 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 624 taaggtgttg tatgataatg 20 <210> 625 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 625 aatatgtgtc atcctgaaga 20 <210> 626 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 626 tcattgtgaa tttcccacat 20 <210> 627 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 627 ttagggatat actgttatac 20 <210> 628 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 628 aaaattaggt tattggattg 20 <210> 629 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 629 ctttcactct catttcttaa 20 <210> 630 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 630 actttcaagt ttattaattt 20 <210> 631 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 631 tactttcatt tatgtctagt 20 <210> 632 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 632 gatatctata ctttcattta 20 <210> 633 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 633 catgttttta caccagctgt 20 <210> 634 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 634 ttacttactc aatttcttct 20 <210> 635 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 635 gtttcagcag tttctgctcc 20 <210> 636 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 636 gggcacttag gagttcctaa 20 <210> 637 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 637 ctctgagagt gtttagaaat 20 <210> 638 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 638 gtgaaagaaa atgctctgag 20 <210> 639 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 639 tacatcagac aaggctcagg 20 <210> 640 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 640 ttctataatc ttatggttaa 20 <210> 641 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 641 gaagtgttct ataatcttat 20 <210> 642 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 642 gtgaaaattt tgtaggttgc 20 <210> 643 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 643 tacaatcagt gtctttcacc 20 <210> 644 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 644 atggttaggg ctatgttatg 20 <210> 645 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 645 gaaataaaac gcaatgtatc 20 <210> 646 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 646 cttgcatgtt gcctttttct 20 <210> 647 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 647 aactctctgc cattattact 20 <210> 648 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 648 taatctcact ggatacagaa 20 <210> 649 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 649 aaacatttta ccattttata 20 <210> 650 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 650 gttattctcc ctcttgaacc 20 <210> 651 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 651 tctgttattc tccctcttga 20 <210> 652 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 652 ggtctgttat tctccctctt 20 <210> 653 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 653 taaggtctgt tattctccct 20 <210> 654 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 654 aaagtaaggt ctgttattct 20 <210> 655 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 655 ctaaaagtaa ggtctgttat 20 <210> 656 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 656 gactaaaagt aaggtctgtt 20 <210> 657 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 657 aatgactaaa agtaaggtct 20 <210> 658 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 658 aaagatatag aactgaaaag 20 <210> 659 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 659 gttggagact tcaatttcct 20 <210> 660 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 660 aaacaacaga gcctcaaata 20 <210> 661 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 661 aaaataccac aaagataggc 20 <210> 662 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 662 aagaatggaa aagatgtatc 20 <210> 663 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 663 taaaagaatg gaaaagatgt 20 <210> 664 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 664 aattttacct cagtataaaa 20 <210> 665 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 665 attaccaaat gccactgtat 20 <210> 666 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 666 gttgcataac atgtgtatta 20 <210> 667 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 667 aattaactgc ttaatgagta 20 <210> 668 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 668 ataaaggtca cttattgtat 20 <210> 669 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 669 aataaaactg atacatacta 20 <210> 670 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 670 aatcaacttt tagctataca 20 <210> 671 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 671 tatcattatg acctaggaat 20 <210> 672 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 672 actggaatta ctaaaaggga 20 <210> 673 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 673 agtagagagt gggatggtat 20 <210> 674 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 674 taagaaacat cacattcaag 20 <210> 675 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 675 tgaacagaat gagaagttta 20 <210> 676 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 676 tctgaacaga atgagaagtt 20 <210> 677 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 677 tggtgtacat tggatatgaa 20 <210> 678 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 678 tttctaacat ttactgtgga 20 <210> 679 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 679 ttctaacata ctaattagca 20 <210> 680 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 680 caccaatgca agccagcttc 20 <210> 681 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 681 tgtttagagg tcaagccctg 20 <210> 682 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 682 atcagtcaaa acatgttctg 20 <210> 683 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 683 tattacacaa ggtattggta 20 <210> 684 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 684 atgaaaggtt tattacacaa 20 <210> 685 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 685 aatcaatttg tgccacaggc 20 <210> 686 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 686 gcagcttata aagagagcca 20 <210> 687 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 687 tttggtaggt aactacgggt 20 <210> 688 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 688 tcggatatag cttttacata 20 <210> 689 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 689 aaactaagca catccgatag 20 <210> 690 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 690 atcatctttg atttgacttt 20 <210> 691 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 691 ttctttatga atctttgaaa 20 <210> 692 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 692 gtaaagagcc acctaaggga 20 <210> 693 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 693 atgagatggg cacagtaaag 20 <210> 694 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 694 tccccagata atgcatagat 20 <210> 695 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 695 ggtggcatag aaggcagcac 20 <210> 696 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 696 ggatgcagca ggagaagaaa 20 <210> 697 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 697 aaggcaaggc taaggagtgc 20 <210> 698 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 698 agagagctag agctaggact 20 <210> 699 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 699 atcccaaagt tacacagaga 20 <210> 700 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 700 cacctgtatc caaaattcaa 20 <210> 701 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 701 catatctgaa gcacagagag 20 <210> 702 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 702 cagtctgctc tgctgctctg 20 <210> 703 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 703 tccagtctgc tctgctgctc 20 <210> 704 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 704 agctcagagg cagcaggagc 20 <210> 705 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 705 ctaagctcca tatttaaatc 20 <210> 706 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 706 ttcaggcttc cttcacagcc 20 <210> 707 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 707 ttcttcaggc ttccttcaca 20 <210> 708 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 708 ggaatcagtg ctacccatta 20 <210> 709 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 709 ttagccatca ttttattctc 20 <210> 710 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 710 ggcccatttt ttcaatctca 20 <210> 711 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 711 catggtcttc cttgactaca 20 <210> 712 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 712 aagccaatgc gcaagaaaag 20 <210> 713 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 713 catccagtta atctctgaca 20 <210> 714 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 714 ctcgcatcca gttaatctct 20 <210> 715 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 715 acaccatccc agaaatggtc 20 <210> 716 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 716 tttctgactc cctatccagt 20 <210> 717 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 717 ttccccaggg tcataggagt 20 <210> 718 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 718 gcactgtccc agttggatta 20 <210> 719 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 719 acccagcaaa atgtgggtct 20 <210> 720 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 720 ttggttgtgg tgaaacccag 20 <210> 721 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 721 tgttaaaaga gaaaagaatc 20 <210> 722 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 722 ttgcagtgat gtactgatgt 20 <210> 723 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 723 ttgtttttat aagcaattag 20 <210> 724 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 724 tataaatatg cccatatgct 20 <210> 725 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 725 ctgcctgcaa ctataaatat 20 <210> 726 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 726 gtatctccta gcccagtgcc 20 <210> 727 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 727 actgtatctc ctagcccagt 20 <210> 728 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 728 gattgcttta ttgcaactaa 20 <210> 729 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 729 cttaaatagt aggaaagcca 20 <210> 730 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 730 gcacactgta caggagggtg 20 <210> 731 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 731 cactgcacac tgtacaggag 20 <210> 732 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 732 gattcactgc acactgtaca 20 <210> 733 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 733 tgttgattca ctgcacactg 20 <210> 734 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 734 atgatgttga ttcactgcac 20 <210> 735 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 735 ggaaatgatg ttgattcact 20 <210> 736 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 736 tgtggaaatg atgttgattc 20 <210> 737 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 737 cagtatctta actggtgaac 20 <210> 738 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 738 acatagaatt atcattatga 20 <210> 739 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 739 atgggttaaa atacttataa 20 <210> 740 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 740 taaaaccttt gtgcataatg 20 <210> 741 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 741 caacaacaaa agcggataaa 20 <210> 742 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 742 atgacactag gttttgcaaa 20 <210> 743 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 743 acctcatgac actaggtttt 20 <210> 744 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 744 gtatagaccc aaactataaa 20 <210> 745 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 745 atgtatagac ccaaactata 20 <210> 746 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 746 tgatctcttc aacaaattgt 20 <210> 747 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 747 aatgttgccg aaagaaaaga 20 <210> 748 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 748 acaagtgtca tatactaaat 20 <210> 749 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 749 aaatttaacc aaggagttac 20 <210> 750 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 750 agccatctaa aagagaaatt 20 <210> 751 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 751 gatcaagaag taaaattatc 20 <210> 752 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 752 cacatgataa tctcaattat 20 <210> 753 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 753 gaaaaattca ctctataggt 20 <210> 754 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 754 ctatagagag atagatatta 20 <210> 755 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 755 agaaaaatgt ctttccaaat 20 <210> 756 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 756 caaatactta aatcaactgt 20 <210> 757 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 757 ggagggagga aaattatttc 20 <210> 758 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 758 agcaaacaac agcaacatgc 20 <210> 759 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 759 aaaatacttt agaaaagtca 20 <210> 760 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 760 cagaattcaa tggacccaca 20 <210> 761 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 761 tcggcaaagg cattattatt 20 <210> 762 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 762 gctttcacct ataggtggcc 20 <210> 763 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 763 gatgttaagc tttcacctat 20 <210> 764 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 764 tacccagggt aggattcatg 20 <210> 765 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 765 gcatacccag ggtaggattc 20 <210> 766 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 766 gtgcataccc agggtaggat 20 <210> 767 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 767 catgtgcata cccagggtag 20 <210> 768 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 768 agatcatgtg catacccagg 20 <210> 769 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 769 agaagatcat gtgcataccc 20 <210> 770 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 770 taagaagatc atgtgcatac 20 <210> 771 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 771 aattaagaag atcatgtgca 20 <210> 772 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 772 gttcagatga acaataagca 20 <210> 773 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 773 actcatgctg gttactaggg 20 <210> 774 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 774 tcatatgggt ggtcgctaat 20 <210> 775 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 775 acactaacga tgaactctaa 20 <210> 776 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 776 taacactaac gatgaactct 20 <210> 777 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 777 ttaaaactca acccagtgca 20 <210> 778 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 778 attcctagag aaaacctagg 20 <210> 779 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 779 agaacaatgt ttcttatgaa 20 <210> 780 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 780 gaaactggga tattaccaat 20 <210> 781 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 781 aaaatggaaa ctgggatatt 20 <210> 782 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 782 aaaaattaaa ggccaacaga 20 <210> 783 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 783 ttatggcagg tagtgaaagg 20 <210> 784 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 784 acaatatgca aaaattaaat 20 <210> 785 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 785 cattctccaa catagatcct 20 <210> 786 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 786 caataataga gactttacca 20 <210> 787 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 787 atatattatg taaatgtaac 20 <210> 788 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 788 aggatggaaa agatatatta 20 <210> 789 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 789 aaacaggttg aaaatgaaag 20 <210> 790 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 790 aaaggcaata ttgaaggaaa 20 <210> 791 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 791 gaattgagtt aataattcct 20 <210> 792 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 792 tctcacagag aaagaggtgg 20 <210> 793 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 793 ttttctataa tctcacagag 20 <210> 794 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 794 ggctcagaaa acatcctttt 20 <210> 795 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 795 atttaattta cacttaatta 20 <210> 796 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 796 actttcctct gcttataact 20 <210> 797 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 797 actatacttt cctctgctta 20 <210> 798 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 798 agcaattaga aatcacatga 20 <210> 799 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 799 aaagcagtaa acaataagtg 20 <210> 800 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 800 tcatatgtaa atccaaaagc 20 <210> 801 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 801 cattgtaagg ataagagata 20 <210> 802 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 802 cagtttgaat tacattgtaa 20 <210> 803 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 803 aattgaactt aaattggcat 20 <210> 804 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 804 ctgcatagga gtagagtttt 20 <210> 805 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 805 aagatggaat ttgcgacatc 20 <210> 806 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 806 acataaaaat gtataaatcc 20 <210> 807 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 807 actgataaag gtaagcacat 20 <210> 808 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 808 cagagaggag agaaggacaa 20 <210> 809 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 809 ggctaggaaa attctcctgg 20 <210> 810 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 810 agggagagct gtcctaaggc 20 <210> 811 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 811 gatatccagg gagagctgtc 20 <210> 812 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 812 ttgaagggaa aattattaat 20 <210> 813 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 813 agctggacgg acagtgttgc 20 <210> 814 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 814 caagacatgc tagggactct 20 <210> 815 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 815 ccaagacatg ctagggactc 20 <210> 816 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 816 gccacagtcc aagacatgct 20 <210> 817 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 817 gcagataatc tgaagataga 20 <210> 818 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 818 tttattacaa actgaaagag 20 <210> 819 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 819 ggtcagataa tgagggcctt 20 <210> 820 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 820 aggataggtg tatgtgagtg 20 <210> 821 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 821 atgaaggtca agccgaatct 20 <210> 822 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 822 aaaagaagta tgtgaaagta 20 <210> 823 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 823 tgtctctaat cctattccaa 20 <210> 824 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 824 agtcttcatg atttggtaaa 20 <210> 825 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 825 agtaagaggc agaattatgt 20 <210> 826 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 826 gggcagcaac agctcttgaa 20 <210> 827 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 827 taataattaa cagtgactgg 20 <210> 828 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 828 aagtcattcc ccaccctggc 20 <210> 829 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 829 tccagcaggg tgtattccag 20 <210> 830 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 830 tcagctgtgg tttccagcag 20 <210> 831 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 831 gcttagagaa tctcagctgt 20 <210> 832 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 832 ggttggaagc tgccagctta 20 <210> 833 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 833 aatggactgc cggcctggag 20 <210> 834 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 834 tgaactactt ggagaccttc 20 <210> 835 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 835 agtgaactac ttggagacct 20 <210> 836 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 836 tcttttatta aacctagttt 20 <210> 837 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 837 ttagctagct gtgggtttgc 20 <210> 838 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 838 acaagagcag acatcttttt 20 <210> 839 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 839 tgtagctttt ctaaaattct 20 <210> 840 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 840 gtatattgta gcttttctaa 20 <210> 841 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 841 cttgatggct gtagcttggt 20 <210> 842 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 842 tttctggatt ctcagtctta 20 <210> 843 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 843 tgcattggta tctgtatatc 20 <210> 844 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 844 gtttcctatt tcatccattt 20 <210> 845 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 845 ctggagtgta agtaaattca 20 <210> 846 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 846 atactctttc cacatttcag 20 <210> 847 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 847 tcctcttgat actctttcca 20 <210> 848 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 848 cttagggtct cctcttgata 20 <210> 849 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 849 cagagtgtct tagggtctcc 20 <210> 850 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 850 atatttctca aatactcttc 20 <210> 851 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 851 tgtgctagaa cactatcttg 20 <210> 852 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 852 tgactctcat ctccctcttc 20 <210> 853 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 853 ccctgactct catctccctc 20 <210> 854 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 854 ccttccttct ttatactgcc 20 <210> 855 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 855 catcaaaatc tctcattcct 20 <210> 856 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 856 aatcatcaaa atctctcatt 20 <210> 857 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 857 ccccaatcat caaaatctct 20 <210> 858 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 858 tagtcagtag tcctaaaaac 20 <210> 859 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 859 agacctctgt ctctgggatt 20 <210> 860 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 860 aaagtcctta cctgttcttg 20 <210> 861 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 861 ttcaccgaaa gtacagtctt 20 <210> 862 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 862 tagtttcacc gaaagtacag 20 <210> 863 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 863 aagtcttttc tcccctcccc 20 <210> 864 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 864 tcaacagtgt tagtgtgtaa 20 <210> 865 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 865 ccttttacct caacagtgtt 20 <210> 866 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 866 agactagtcc ctgtgtagtc 20 <210> 867 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 867 ccaagactag tccctgtgta 20 <210> 868 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 868 aactgtcaga ggaagaaatg 20 <210> 869 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 869 cgaacagaac ttgccgatgt 20 <210> 870 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 870 ttgtataggg agatgataga 20 <210> 871 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 871 taacctttta ttattataga 20 <210> 872 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 872 taaactaaag taactggttt 20 <210> 873 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 873 ccaggaagct ctggagggaa 20 <210> 874 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 874 actctattat atattttggt 20 <210> 875 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 875 gttataaaag tacttttttt 20 <210> 876 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 876 ggatacttcc tctaccccaa 20 <210> 877 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 877 acagtggata cttcctctac 20 <210> 878 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 878 ctgccttttc attactattt 20 <210> 879 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 879 gttttaaagt ggtaattgaa 20 <210> 880 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 880 tcatcatcaa cctaaccgag 20 <210> 881 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 881 ccatcttgga accggatgac 20 <210> 882 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 882 gtaattgagg tggccatatc 20 <210> 883 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 883 gagtcctaaa tgtctcatac 20 <210> 884 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 884 ggttttagtc cactggttca 20 <210> 885 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 885 ctagtcatgt atctacagcc 20 <210> 886 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 886 gtatatggct tacacaggct 20 <210> 887 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 887 gagatttcag actacctgta 20 <210> 888 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 888 attgacccag cccatggcac 20 <210> 889 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 889 gcgcattgag caaaattcca 20 <210> 890 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 890 gcataacgat aatcatgtgg 20 <210> 891 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 891 ggctataggc catttattca 20 <210> 892 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 892 ttgaataact acctaggctc 20 <210> 893 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 893 ccggtgcagg aatccaggat 20 <210> 894 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 894 taacaataag ataaaggcgc 20 <210> 895 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 895 ggcaagcaaa gactacaccg 20 <210> 896 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 896 gctcctaaca ttgtatcccc 20 <210> 897 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 897 ctctaccaag ctatccaagt 20 <210> 898 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 898 gtcctattgg agggccgcac 20 <210> 899 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 899 gtcctccaat aagcttctga 20 <210> 900 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 900 gggacaatac tgcaatcctt 20 <210> 901 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 901 agagacctca agacctatag 20 <210> 902 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 902 gactacttca acctgatacc 20 <210> 903 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 903 gggcatcatt aacataagct 20 <210> 904 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 904 acaaacgggc tatgtgagat 20 <210> 905 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 905 cactgagttt ttgtagttcg 20 <210> 906 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 906 ggcagttgtg atagtcaaca 20 <210> 907 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 907 tagaggccct cttgtttcaa 20 <210> 908 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 908 ggattttatt ggtcatctcg 20 <210> 909 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 909 gtagttactt atactggttc 20 <210> 910 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 910 gtgggttcct gatggagtcc 20 <210> 911 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 911 ctaggttgca taaagccagg 20 <210> 912 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 912 gccttaaaag ggttccctgt 20 <210> 913 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 913 ggtcatgatg tatgccatta 20 <210> 914 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 914 atctagcttg aatggatacc 20 <210> 915 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 915 gttctttctc ggtcaaacta 20 <210> 916 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 916 tacgagttgc tggtttcagc 20 <210> 917 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 917 ggttagggct atgttatgtt 20 <210> 918 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 918 gattccactt gtgtatgcac 20 <210> 919 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 919 catatactaa atgttgccga 20 <210> 920 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 920 atacagaatt caatggaccc 20 <210> 921 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 921 gcctaggacc agttggttca 20 <210> 922 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 922 ggctgttgta cattcctagt 20 <210> 923 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 923 ccctaagctt agatataccc 20 <210> 924 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 924 aggtgggaaa ccggttccca 20 <210> 925 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 925 ggtcggtccc caccaaagga 20 <210> 926 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 926 gccatgtacg accctcatca 20 <210> 927 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 927 tactataata cgggacctca 20 <210> 928 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 928 atcacattca aggtagcccc 20 <210> 929 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 929 tgaccagcaa taggctctgc 20 <210> 930 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 930 actggccttt gggtcggata 20 <210> 931 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 931 ggagtcccca gataatgcat 20 <210> 932 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 932 ggatgggcta agagtcacct 20 <210> 933 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 933 ggtattaagg cccttggcca 20 <210> 934 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 934 ggcccgatga caccagccac 20 <210> 935 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 935 taacagtcct gtaaccagac 20 <210> 936 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 936 ccccctgaga tccatgaggt 20 <210> 937 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 937 cagttgtgca gttgttaact 20 <210> 938 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 938 aaccagatgg ctgagctatt 20 <210> 939 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 939 ttaggccata cctcttccat 20 <210> 940 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 940 ttagtctgtt gtgtgactcc 20 <210> 941 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 941 ccacctaaga gctatccgct 20 <210> 942 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 942 ggccgaccag ctctgaaagt 20 <210> 943 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 943 accagggtgg tattataaag 20 <210> 944 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 944 caggttgtgg aggttgttcc 20 <210> 945 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 945 gttgtctggc atggagatcc 20 <210> 946 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 946 gttgattgga ggcactgcag 20 <210> 947 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 947 tggtgagtaa atcaatcacg 20 <210> 948 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 948 cccttcaaca tgtgttaacg 20 <210> 949 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 949 cgtggctgta cctgcagtgc 20 <210> 950 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 950 gactctgatt gattcagtgc 20 <210> 951 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 951 agtacaaacc actaagggta 20 <210> 952 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 952 gtgccatata atgttgaagc 20 <210> 953 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 953 cgtgtctgaa ctggcctgtg 20 <210> 954 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 954 cataacctct cctcgagaca 20 <210> 955 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 955 tctgtcacgc ttcccttggc 20 <210> 956 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 956 tcactggtgt ggtatcatgc 20 <210> 957 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 957 gattgcatct cttgcagcac 20 <210> 958 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 958 ctcacctgtg tatatgagtc 20 <210> 959 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 959 acactgttag agcccccaca 20 <210> 960 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 960 gcataggaat gggaccatag 20 <210> 961 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 961 gcatcataca tagtgtatgc 20 <210> 962 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 962 cttgtctcac aattgttacc 20 <210> 963 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 963 taactgtagc gcattgagca 20 <210> 964 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 964 gctagtcact cattgagaag 20 <210> 965 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 965 tagataggct ataggccatt 20 <210> 966 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 966 gcatatatct taactcaccc 20 <210> 967 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 967 aaaagccggt gcaggaatcc 20 <210> 968 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 968 taagtgccca tggcatagtc 20 <210> 969 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 969 gagtgctgaa gaacatcccc 20 <210> 970 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 970 caagtctact accaataagt 20 <210> 971 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 971 cgtcagcatt gcttgatctc 20 <210> 972 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 972 tatttgtcct attggagggc 20 <210> 973 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 973 catggtgagg gtctcaatga 20 <210> 974 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 974 gagacatgtg ccagttcaag 20 <210> 975 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 975 ggacactggc acatctatag 20 <210> 976 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 976 ctgtataact gattgactac 20 <210> 977 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 977 gctcatctat ggattgcatt 20 <210> 978 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 978 gtacaaacgg gctatgtgag 20 <210> 979 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 979 agctataggt acctgaagtt 20 <210> 980 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 980 cttagcttgc ccagagcata 20 <210> 981 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 981 gcgaatagag gccctcttgt 20 <210> 982 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 982 gatgtgtata ggtgttggtc 20 <210> 983 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 983 ccattttggt gctataaccc 20 <210> 984 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 984 cttataggtg ggttcctgat 20 <210> 985 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 985 tctctaggtt gcataaagcc 20 <210> 986 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 986 gcacttgtat agttcatccc 20 <210> 987 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 987 atcctgcatc cgaggcatga 20 <210> 988 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 988 gtggttgcct tagtattaca 20 <210> 989 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 989 ctgtaaggtg atatctatac 20 <210> 990 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 990 tgttcatacg agttgctggt 20 <210> 991 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 991 cgcaatgtat caggcaacag 20 <210> 992 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 992 gagggcacaa tgattccact 20 <210> 993 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 993 ggagttacaa gtgtcatata 20 <210> 994 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 994 ggctctatgc acttaaggga 20 <210> 995 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 995 gatcatgtgc atacccaggg 20 <210> 996 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 996 ggtcagattc ctaaatacgc 20 <210> 997 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 997 gtgtcatatg tagcaattag 20 <210> 998 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 998 cacctgtata ggagaattgt 20 <210> 999 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 999 ccactcccgt ggcaacatga 20 <210> 1000 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1000 gggtaagagg tcggtcccca 20 <210> 1001 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1001 ggaggccatg tacgaccctc 20 <210> 1002 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1002 gctgcaatac tataatacgg 20 <210> 1003 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1003 agctgaggtc accgatcaga 20 <210> 1004 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1004 aacagtgacc agcaataggc 20 <210> 1005 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1005 ctaactggcc tttgggtcgg 20 <210> 1006 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1006 gggaggagtc cccagataat 20 <210> 1007 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1007 ggcccaagtg atgacatatc 20 <210> 1008 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1008 gtaaggcatg gtcttccttg 20 <210> 1009 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1009 aatatggccc gatgacacca 20 <210> 1010 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1010 gcaagattaa cagtcctgta 20 <210> 1011 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1011 tcagctcaac accccctgag 20 <210> 1012 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1012 agggtcagtt gtgcagttgt 20 <210> 1013 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1013 gcaaggaatc atgtggctcc 20 <210> 1014 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1014 ccaaagattt aggccatacc 20 <210> 1015 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1015 gtaaccttca cataagctgc 20 <210> 1016 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1016 ggcctagctt ccacctaaga 20 <210> 1017 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1017 cgctggccga ccagctctga 20 <210> 1018 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1018 cgtctaccag ggtggtatta 20 <210> 1019 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1019 atactccagg ttgtggaggt 20 <210> 1020 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1020 caaattggtg aatgttcccc 20 <210> 1021 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1021 tctcatgacc acctaattga 20 <210> 1022 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1022 ccgtgctgct ttcttgagtg 20 <210> 1023 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1023 acatgcttgc atccaggccc 20 <210> 1024 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1024 cggaacccac agtagaggca 20 <210> 1025 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1025 ctagggactc tgattgattc 20 <210> 1026 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1026 accaggcata agtacaaacc 20 <210> 1027 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1027 ctgagtgcca tataatgttg 20 <210> 1028 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1028 aaggctctca gggtaagacg 20 <210> 1029 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1029 cgtggaacac tgacccatca 20 <210> 1030 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1030 cagcatgtaa ctcatgttgt 20 <210> 1031 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1031 gttctaaagt cggttgtgtc 20 <210> 1032 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1032 agagtaggcc aggtgtcaaa 20 <210> 1033 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1033 taccagtgag taaactggcc 20 <210> 1034 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1034 gtactcccca tgcacacttg 20 <210> 1035 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1035 acggattatc ataccctccc 20 <210> 1036 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1036 gtcttgtaaa cccttaccag 20 <210> 1037 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1037 ccgttactta agctgtggta 20 <210> 1038 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1038 tagtgccagt aggacttact 20 <210> 1039 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1039 ggacccttaa gtcataaaga 20 <210> 1040 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1040 gaccaaatga gcatcacatc 20 <210> 1041 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1041 cctgtatgta tggcttatgc 20 <210> 1042 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1042 atccatagtg atctgggaac 20 <210> 1043 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1043 actataattg ggaatggtca 20 <210> 1044 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1044 gatttgaccc ttatggagac 20 <210> 1045 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1045 tattccctat ccagggtaga 20 <210> 1046 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1046 ttatcctgtt gcaatagaac 20 <210> 1047 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1047 attagattaa aatctggccg 20 <210> 1048 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1048 gactcataag acaggatgcc 20 <210> 1049 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1049 ccagccaggt gtcttatatc 20 <210> 1050 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1050 cagttgtgta ttgactaagt 20 <210> 1051 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1051 aagactatcc tggtatgact 20 <210> 1052 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1052 tcgatgttct tgcttccctg 20 <210> 1053 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1053 ggcagctcct gacaaattag 20 <210> 1054 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1054 agacccctcc cttaatgtaa 20 <210> 1055 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1055 acctgggtat tgctgtccaa 20 <210> 1056 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1056 ctcacccttt actaaggtgc 20 <210> 1057 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1057 ccattggtat gagagatgct 20 <210> 1058 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1058 gtcagactta ttgaggatgg 20 <210> 1059 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1059 ttactcctct ggtgtgctga 20 <210> 1060 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1060 gcgcacttgg gagccagcca 20 <210> 1061 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1061 ttactgactg gccttaggag 20 <210> 1062 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1062 gtagtatgca ttgacaagct 20 <210> 1063 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1063 gagtatatta cctccaggtt 20 <210> 1064 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1064 gtattgctgc tctagctcta 20 <210> 1065 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1065 acggacctca tacagtgagt 20 <210> 1066 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1066 gggctcttgg aagtctagtt 20 <210> 1067 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1067 acatacttgg ttgcagacgc 20 <210> 1068 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1068 taggtttgcg gatgccagtg 20 <210> 1069 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1069 tacacagtgg gatttgcccc 20 <210> 1070 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1070 atggcctgac taggcattga 20 <210> 1071 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1071 ggttactagg gccagagaat 20 <210> 1072 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1072 tgttaataga ctgcgattat 20 <210> 1073 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1073 gggcggagct gcataggagt 20 <210> 1074 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1074 acaatggacc acctaagacc 20 <210> 1075 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1075 caacccttac tctgccaggg 20 <210> 1076 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1076 tgtgcaatag cctaaatgcc 20 <210> 1077 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1077 ctactatgaa gttatgcacc 20 <210> 1078 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1078 gttagcctta cagcaaatac 20 <210> 1079 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1079 tactaattag caagccactg 20 <210> 1080 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1080 gtgtcaaatc aatttgtgcc 20 <210> 1081 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1081 ctaagcacat ccgatagtca 20 <210> 1082 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1082 ggagtgctct ttgtggatgc 20 <210> 1083 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1083 acccatggct catcagtggg 20 <210> 1084 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1084 ggcagctctt tgtaggccca 20 <210> 1085 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1085 ggagtgggtt cctataagga 20 <210> 1086 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1086 ggactaatag gcctttctac 20 <210> 1087 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1087 ctacagtacc aggtcatttg 20 <210> 1088 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1088 caccaccaac cttaaatagt 20 <210> 1089 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1089 ccatgccaca gattggcttg 20 <210> 1090 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1090 cggagcctta cgcttggctg 20 <210> 1091 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1091 cagtctgtct ctgtgtaccg 20 <210> 1092 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1092 ggttgacagg acatgctgtc 20 <210> 1093 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1093 gttagccgag cattggcttc 20 <210> 1094 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1094 cccatggtgg tggaatgctg 20 <210> 1095 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1095 tcccgcacca tgcattctga 20 <210> 1096 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1096 tcagcttcct tcagtgggcg 20 <210> 1097 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1097 gatctcacac atggcactgc 20 <210> 1098 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1098 taccagtaaa gggtagtata 20 <210> 1099 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1099 gtaaatatac acttgggccc 20 <210> 1100 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1100 tagctgaacc tgtggctagg 20 <210> 1101 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1101 agtgtcaggc tgtaagggat 20 <210> 1102 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1102 gccataggtt tcaggctgat 20 <210> 1103 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1103 gagatgggct atgagccatc 20 <210> 1104 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1104 ggaccagcgg gccgaacgca 20 <210> 1105 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1105 atgcaaaggt gtcgatttgt 20 <210> 1106 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1106 ggtccataga tgtcagttac 20 <210> 1107 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1107 attaatgttc tatggtggat 20 <210> 1108 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1108 ggagtagaat gcccactggg 20 <210> 1109 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1109 gagacctgaa tataccttac 20 <210> 1110 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1110 ggtatgccag gtttttgaca 20 <210> 1111 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1111 ccgtgtaatg acacacctct 20 <210> 1112 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1112 aggctatagt caaagggtgg 20 <210> 1113 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1113 gtgtcagtca atcattgaga 20 <210> 1114 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1114 ggtcttattt accattggca 20 <210> 1115 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1115 taacatgttg cttgcactcc 20 <210> 1116 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1116 gctcaaacta gaatacccca 20 <210> 1117 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1117 gtctaggtct cacgctgtgt 20 <210> 1118 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1118 gacagtggag tcaagttggt 20 <210> 1119 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1119 ggactccaca cacctactag 20 <210> 1120 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1120 gtgggatggc tgtcaatgct 20 <210> 1121 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1121 gataattgag gagttcacca 20 <210> 1122 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1122 gatccaaaca agcaccctcc 20 <210> 1123 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1123 tatcacagtt gcttgaccct 20 <210> 1124 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1124 gatctattat gagggcatca 20 <210> 1125 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1125 agctttagta tgtcgagaac 20 <210> 1126 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1126 gtgtggatgg tatcctggtc 20 <210> 1127 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1127 ggaatgcttg atctgtgggc 20 <210> 1128 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1128 gctagactag ttgaaatcgg 20 <210> 1129 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1129 ccctcccatc agtgaagatt 20 <210> 1130 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1130 gctttagagg tcaaatagtg 20 <210> 1131 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1131 ctggtcttcc tcgaggatag 20 <210> 1132 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1132 gtcatctcgg gtatataaat 20 <210> 1133 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1133 ggacaagtct tatagagaac 20 <210> 1134 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1134 gttccaagta tgggctgctg 20 <210> 1135 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1135 gtcaacatgt gcttgcaagc 20 <210> 1136 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1136 gctgttgata cgctccttca 20 <210> 1137 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1137 gaggcactga agttcactac 20 <210> 1138 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1138 agggtcccac ttgtttaggt 20 <210> 1139 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1139 cgtattaagg tgttgtatga 20 <210> 1140 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1140 ccttgtgaca atagtagtga 20 <210> 1141 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1141 ggctagatgg agcttgagcc 20 <210> 1142 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1142 cgtgagctat ctgtacaaaa 20 <210> 1143 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1143 gtgcataatg gtctaccaca 20 <210> 1144 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1144 tgaagatagg tcagttaacg 20 <210> 1145 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1145 gttaagcttt cacctatagg 20 <210> 1146 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1146 tgatcatatg ggtggtcgct 20 <210> 1147 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1147 attgtcctcc tggtaaccac 20 <210> 1148 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1148 gggactggtg ccacaccatc 20 <210> 1149 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1149 ctaacctgga tctcagatag 20 <210> 1150 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1150 ctgggcccca attcagtaat 20 <210> 1151 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1151 ttggtaaagg agggaatcgg 20 <210> 1152 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1152 tccaggatat atgttagtcc 20 <210> 1153 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1153 tagctacaat aagttgtagc 20 <210> 1154 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1154 gagggccatg ttaaaggcct 20 <210> 1155 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1155 ttttggtagg taactacggg 20 <210> 1156 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1156 tgtagctcag ctcaatgtgt 20 <210> 1157 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1157 gaactgcact gggttgtctc 20 <210> 1158 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1158 gtattgcact cacatactgt 20 <210> 1159 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1159 agccaatgcg caagaaaagt 20 <210> 1160 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1160 cataggcata aagcctccta 20 <210> 1161 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1161 tcccagaaat ggtcctcgca 20 <210> 1162 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1162 atgtgggtct gcaccaagtt 20 <210> 1163 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1163 ggtgaactcc tgtgactgat 20 <210> 1164 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1164 gtggagtagg tatattagtc 20 <210> 1165 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1165 gtattcctga agtagtcctg 20 <210> 1166 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1166 agaaattggg ccgcctctgt 20 <210> 1167 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1167 gtgcttagtg aactgtgggc 20 <210> 1168 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1168 ccggcatgca tcagctctga 20 <210> 1169 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1169 taagaagctt gcctttcgat 20 <210> 1170 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1170 gcagtgctac tgtgccctta 20 <210> 1171 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1171 tccagccctc agtatataga 20 <210> 1172 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1172 ccgaagtgga agtagtcatg 20 <210> 1173 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1173 tgaatgccac cgtgattgca 20 <210> 1174 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1174 cgtagtgtca tcaccataaa 20 <210> 1175 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1175 gttgtgtctg agggatatcc 20 <210> 1176 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1176 gccgaatctt gacatacagg 20 <210> 1177 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1177 gattaccaaa aagggaccag 20 <210> 1178 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1178 ctcctaccaa taatggagtc 20 <210> 1179 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1179 cggacacact gggaccagcg 20 <210> 1180 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1180 gctcctatca agcttttccc 20 <210> 1181 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1181 tgaggtgcat tttctagccc 20 <210> 1182 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1182 atctatggag tcatctcccc 20 <210> 1183 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1183 ggtagaggtt aatctatgtc 20 <210> 1184 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1184 cgtcggtaaa ggaagctact 20 <210> 1185 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1185 tcataaggac aaggtatgcc 20 <210> 1186 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1186 ggacctcatt agatcagtca 20 <210> 1187 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1187 ggcagttgag tggtgtcagt 20 <210> 1188 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1188 ggattgcatc acatgtgtca 20 <210> 1189 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1189 tataagtgtc cataaaggtc 20 <210> 1190 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1190 ggcattaaca tgttgcttgc 20 <210> 1191 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1191 gaattgataa gtggtcttct 20 <210> 1192 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1192 gggaagtcta ggtctcacgc 20 <210> 1193 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1193 ctacatatga cagtggagtc 20 <210> 1194 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1194 tgagtggact ccacacacct 20 <210> 1195 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1195 gatattgcag tgggatggct 20 <210> 1196 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1196 cgtgatagtg ctattgtgag 20 <210> 1197 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1197 catcgatcca aacaagcacc 20 <210> 1198 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1198 gcttagctac tcacccctgt 20 <210> 1199 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1199 cccacttgat ctattatgag 20 <210> 1200 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1200 ccctaatata gggcagatga 20 <210> 1201 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1201 agtgtggatg gtatcctggt 20 <210> 1202 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1202 ggatttgagc ctgctatgtc 20 <210> 1203 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1203 cattcagcta gactagttga 20 <210> 1204 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1204 tatggccctc ccatcagtga 20 <210> 1205 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1205 tagattgggc tttagaggtc 20 <210> 1206 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1206 acatctggtc ttcctcgagg 20 <210> 1207 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1207 ggtcatctcg ggtatataaa 20 <210> 1208 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1208 accgaaggag ttcctttagc 20 <210> 1209 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1209 ggcagttcca agtatgggct 20 <210> 1210 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1210 gtggagccag ctgtcaacat 20 <210> 1211 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1211 tggaatgtat cctgtacggg 20 <210> 1212 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1212 gtgttatact attgtggtgc 20 <210> 1213 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1213 gtttgttagg gtcccacttg 20 <210> 1214 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1214 tctgctattg ttggatatcg 20 <210> 1215 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1215 atggttagtt taagaaatcg 20 <210> 1216 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1216 gagtcctggt tgatgtggtg 20 <210> 1217 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1217 acgggcatgc tttataatta 20 <210> 1218 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1218 aacctttgtg cataatggtc 20 <210> 1219 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1219 cactctatag gttcaagcag 20 <210> 1220 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1220 ccagggtagg attcatggtc 20 <210> 1221 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1221 tgttgtatgc aggttcatca 20 <210> 1222 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1222 gatacattgt cctcctggta 20 <210> 1223 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1223 acacttgaag ctgttgagtc 20 <210> 1224 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1224 cgtgaaggaa tgatctctct 20 <210> 1225 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1225 cctaatctat gctgggcccc 20 <210> 1226 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1226 gagagtaagt tactagaggc 20 <210> 1227 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1227 tgggcagatt gatcacctag 20 <210> 1228 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1228 tactaggcct gctctactgg 20 <210> 1229 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1229 ttagaggtca agccctgtgt 20 <210> 1230 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1230 gggtcggata tagcttttac 20 <210> 1231 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1231 gcttatgtag ctcagctcaa 20 <210> 1232 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1232 ttgggacatc ccaaagttac 20 <210> 1233 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1233 ggaacatcat gttagccatc 20 <210> 1234 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1234 gatgcatcaa gccaatgcgc 20 <210> 1235 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1235 gaacctctac agagagacta 20 <210> 1236 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1236 gttctgtata caccatccca 20 <210> 1237 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1237 gcaaaatgtg ggtctgcacc 20 <210> 1238 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1238 taactggtga actcctgtga 20 <210> 1239 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1239 ccccagaagt ggagtaggta 20 <210> 1240 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1240 cctcaagatc aacagacccc 20 <210> 1241 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1241 cagtcaggta caggtgttgg 20 <210> 1242 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1242 gtgagggtgc ttagtgaact 20 <210> 1243 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1243 gtcagaacaa tccggcatgc 20 <210> 1244 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1244 gagtgctcca cacttctgtc 20 <210> 1245 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1245 gcttgcagtg ctactgtgcc 20 <210> 1246 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1246 tcgatacctg cttttgtgac 20 <210> 1247 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1247 cataaccgaa gtggaagtag 20 <210> 1248 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1248 tacttcatga ctgcctagtt 20 <210> 1249 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1249 aagaagggca tatatctacg 20 <210> 1250 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1250 cggacagtgt tgctgttagg 20 <210> 1251 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1251 ggtcaagccg aatcttgaca 20 <210> 1252 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1252 tgactgggta aggcaggatc 20 <210> 1253 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1253 agtactccta ccaataatgg 20 <210> 1254 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1254 ggcagtgcat tcaactgtag 20 <210> 1255 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1255 cgtgggttag tccaagtaac 20 <210> 1256 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1256 gcccattatg tagtctatag 20 <210> 1257 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1257 gacgaaggca gtcactctgc 20 <210> 1258 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1258 gggagaacta catctcacct 20 <210> 1259 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1259 ccccattacc acggtctctt 20 <210> 1260 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1260 agcagtcttt atctacaggc 20 <210> 1261 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1261 ttgatgacct ggtaagggat 20 <210> 1262 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1262 cgcaataaga ttccattgcc 20 <210> 1263 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1263 acgataactg tagcgcattg 20 <210> 1264 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1264 gcaagtatgc tagtcactca 20 <210> 1265 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1265 ccattagata ggctataggc 20 <210> 1266 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1266 tcgccgctga ttttaaagat 20 <210> 1267 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1267 ggttcaaaag ccggtgcagg 20 <210> 1268 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1268 gttgttctta agtgcccatg 20 <210> 1269 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1269 gcactttgca tgagaatagg 20 <210> 1270 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1270 tccagacaag tctactacca 20 <210> 1271 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1271 tctactcctt gctacaaacg 20 <210> 1272 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1272 gggatcccca aatagagcca 20 <210> 1273 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1273 caatagtgta ggtgacatgg 20 <210> 1274 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1274 gcatgtgggc ctctattaag 20 <210> 1275 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1275 gtatggtatc ttgcagtagc 20 <210> 1276 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1276 atagcccttt cagcacactt 20 <210> 1277 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1277 gctggcaata tgtcaacctt 20 <210> 1278 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1278 tgtacaaacg ggctatgtga 20 <210> 1279 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1279 catatgaagc tataggtacc 20 <210> 1280 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1280 ggtagttcac aactcttcct 20 <210> 1281 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1281 tctgcgaata gaggccctct 20 <210> 1282 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1282 gacacgctga ctatgatgtg 20 <210> 1283 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1283 cttgcccatg gatggttgtc 20 <210> 1284 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1284 gtggcttata ggtgggttcc 20 <210> 1285 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1285 ggttgtatgc cttctgcatt 20 <210> 1286 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1286 ccttgcagca cttgtatagt 20 <210> 1287 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1287 actatcctgc atccgaggca 20 <210> 1288 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1288 atataattga gggccaccat 20 <210> 1289 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1289 cctttagagg gatttgtgta 20 <210> 1290 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1290 cttaacatgt tcatacgagt 20 <210> 1291 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1291 gctgatcaca ttacccatcc 20 <210> 1292 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1292 gatgtatcac gcaaacaatt 20 <210> 1293 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1293 accaaggagt tacaagtgtc 20 <210> 1294 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1294 ggccaggatg gtcaacctta 20 <210> 1295 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1295 tttttgccac agccgcttgg 20 <210> 1296 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1296 cgaataattg catgccaact 20 <210> 1297 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1297 ggtttagtgt catatgtagc 20 <210> 1298 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1298 gcacacacct gtataggaga 20 <210> 1299 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1299 cctgccactc ccgtggcaac 20 <210> 1300 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1300 ttatgggtaa gaggtcggtc 20 <210> 1301 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1301 ggtatggagg ccatgtacga 20 <210> 1302 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1302 gcgcccggca agagattcac 20 <210> 1303 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1303 ttgcataata ggaggtcctt 20 <210> 1304 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1304 gggcttacaa cctctcaatt 20 <210> 1305 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1305 cctaactggc ctttgggtcg 20 <210> 1306 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1306 gtctgcacag gtggcataga 20 <210> 1307 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1307 gtccagaggt catatggccc 20 <210> 1308 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1308 gcataagtaa ggcatggtct 20 <210> 1309 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1309 cttcgggcaa atatggcccg 20 <210> 1310 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1310 ggtgctacag tcatactatc 20 <210> 1311 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1311 gtgatcagct caacaccccc 20 <210> 1312 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1312 taataaaggg tcagttgtgc 20 <210> 1313 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1313 cactgcctaa gcaaggaatc 20 <210> 1314 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1314 tgccccaaag atttaggcca 20 <210> 1315 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1315 tcagacatgg taaccttcac 20 <210> 1316 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1316 attgcaggcc tagcttccac 20 <210> 1317 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1317 ggtattgagt aggacttctc 20 <210> 1318 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1318 cttaaggagg caactcctga 20 <210> 1319 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1319 atatactcca ggttgtggag 20 <210> 1320 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1320 gagccaggtt cctgttcacg 20 <210> 1321 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1321 ccgtctttag gaacttaaat 20 <210> 1322 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1322 agcacaaccc ccgtgctgct 20 <210> 1323 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1323 tacccaacat gcttgcatcc 20 <210> 1324 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1324 atacacggaa cccacagtag 20 <210> 1325 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1325 catgctaggg actctgattg 20 <210> 1326 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1326 gttagaccag gcataagtac 20 <210> 1327 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1327 tgcagctgag tgccatataa 20 <210> 1328 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1328 actacttgga gaccttcacc 20 <210> 1329 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1329 gctcctgaca aattagcact 20 <210> 1330 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1330 cggatgcagg gcacccttgg 20 <210> 1331 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1331 catgatataa ggagaaacgc 20 <210> 1332 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1332 atcttgcggc tgtctcccag 20 <210> 1333 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1333 tcccatagtt atatggctca 20 <210> 1334 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1334 ctgcatgtta gattgggcat 20 <210> 1335 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1335 gctgtgatgc taggatgcat 20 <210> 1336 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1336 agacatagac cccagacggt 20 <210> 1337 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1337 cccttaccag aatagcatcc 20 <210> 1338 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1338 tggtagacca ctgattcccc 20 <210> 1339 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1339 agcaagggtc ttagtgccaa 20 <210> 1340 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1340 gtctgtatat ttagaccacg 20 <210> 1341 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1341 gtcaacatta tatcgatgca 20 <210> 1342 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1342 gtatggctta tgcatgctat 20 <210> 1343 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1343 tgggcaggtc aacttggtat 20 <210> 1344 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1344 aaaaggtgat taggcggccg 20 <210> 1345 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1345 tgacccttat ggagacttat 20 <210> 1346 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1346 tccagggtag aagactagca 20 <210> 1347 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1347 gcaatagaac agatggccat 20 <210> 1348 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1348 gtaccaaagt ggctgctcac 20 <210> 1349 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1349 actgccctct tcgaagagat 20 <210> 1350 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1350 gattatctca gacatgccat 20 <210> 1351 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1351 ccttaagcaa ggagttcact 20 <210> 1352 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1352 atcctggtat gactgtcagt 20 <210> 1353 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1353 ggctctcatc taaataagcc 20 <210> 1354 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1354 aaccctaagg tgaagtctgt 20 <210> 1355 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1355 gggtattgct gtccaaatgg 20 <210> 1356 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1356 gtgttatggt tcccattcag 20 <210> 1357 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1357 cctgctcaaa tctgcgaata 20 <210> 1358 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1358 gacttattga ggatggtgtg 20 <210> 1359 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1359 tgaactccca caaggtactc 20 <210> 1360 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1360 aggcatttgg agcattcggg 20 <210> 1361 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1361 actttcatca gttagtcagg 20 <210> 1362 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1362 cattgacaag ctattgcagc 20 <210> 1363 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1363 ttttatggct tatagcagcg 20 <210> 1364 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1364 cacgcccaaa tggaactcta 20 <210> 1365 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1365 gtgagttata gagtgttccc 20 <210> 1366 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1366 tgggcactta ggagttccta 20 <210> 1367 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1367 gctgtatctg tggtttagca 20 <210> 1368 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1368 gcggatgcca gtggccgaga 20 <210> 1369 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1369 gctatacccc taggatcaga 20 <210> 1370 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1370 taggcattga atgagggccc 20 <210> 1371 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1371 gtatggactt gtcttatggc 20 <210> 1372 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1372 aatagactgc gattatacaa 20 <210> 1373 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1373 cgcaattgaa cttaaattgg 20 <210> 1374 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1374 ggaccaccta agacctcaag 20 <210> 1375 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1375 ggctaaagta atcttatggg 20 <210> 1376 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1376 gtgcaatagc ctaaatgcca 20 <210> 1377 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1377 ggattaggca gcttcactac 20 <210> 1378 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1378 gcaaatacaa tggtaatcgc 20 <210> 1379 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1379 ctggtgtaca ttggatatga 20 <210> 1380 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1380 gcaagaggta ctgtaagccc 20 <210> 1381 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1381 atccgatagt caaactatga 20 <210> 1382 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1382 aaacaccctt ccaatgaggg 20 <210> 1383 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1383 gttcactagc atctgctaca 20 <210> 1384 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1384 gctctttgta ggcccaaggg 20 <210> 1385 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1385 ggttcctata aggaataggc 20 <210> 1386 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1386 taataggcct ttctacagct 20 <210> 1387 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1387 ccccagggtc ataggagtgt 20 <210> 1388 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1388 ccaccaacct taaatagtag 20 <210> 1389 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1389 ccacagattg gcttggaatg 20 <210> 1390 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1390 gccttacgct tggctgacat 20 <210> 1391 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1391 gtctctgtgt accgagctca 20 <210> 1392 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1392 gtctggtggc caagtgcttc 20 <210> 1393 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1393 agccgagcat tggcttcata 20 <210> 1394 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1394 ggtggtggaa tgctgtccac 20 <210> 1395 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1395 ctccaccaaa tacttagccc 20 <210> 1396 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1396 taaatgtcag gaggtccccc 20 <210> 1397 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1397 ccttgggtta ttcttaccgt 20 <210> 1398 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1398 ggtagtataa gaatggttcc 20 <210> 1399 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1399 atacacttgg gcccaaatgg 20 <210> 1400 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1400 gctagcattt gagagttata 20 <210> 1401 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1401 ggctgtaagg gattaagatg 20 <210> 1402 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1402 ctgttacagg gagacaatct 20 <210> 1403 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1403 accctgcaca aatggactgc 20 <210> 1404 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1404 gggcaccccc gtcaccgtgc 20 <210> 1405 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1405 agattttccg acctatgtca 20 <210> 1406 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1406 atcgccatgg tcacttgcca 20 <210> 1407 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1407 ggcaaagcaa gttcgccaca 20 <210> 1408 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1408 atcatacagg tcacttggct 20 <210> 1409 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1409 attggactag gtaacagtga 20 <210> 1410 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1410 caggctattt cttagtggac 20 <210> 1411 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1411 caagggtaac ctatagctga 20 <210> 1412 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1412 gcatatgcac acttggatca 20 <210> 1413 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1413 accctgaaaa caatcaatcg 20 <210> 1414 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1414 acgataatca tgtggcctga 20 <210> 1415 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1415 gactaactat acaggtctct 20 <210> 1416 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1416 actacctagg ctcacttgct 20 <210> 1417 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1417 ccaggatgct aatgctccta 20 <210> 1418 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1418 gcgctttcac caagaaattt 20 <210> 1419 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1419 gcaaagacta caccgtgaca 20 <210> 1420 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1420 cccctgcatt cagcttatag 20 <210> 1421 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1421 gctatccaag tgacacagta 20 <210> 1422 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1422 gggccgcaca tctggacctc 20 <210> 1423 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1423 tacaaaacga cctaaagacc 20 <210> 1424 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1424 ctgcaatcct taagacttga 20 <210> 1425 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1425 cctcaagacc tataggacct 20 <210> 1426 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1426 atacattgcc agcactaagg 20 <210> 1427 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1427 gatttaccac acatataggc 20 <210> 1428 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1428 cgggctatgt gagataattc 20 <210> 1429 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1429 ggctgacatg ccccttttaa 20 <210> 1430 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1430 gttgtgatag tcaacaattg 20 <210> 1431 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1431 aggccctctt gtttcaattg 20 <210> 1432 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1432 gattttattg gtcatctcgg 20 <210> 1433 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1433 gcctttctat ttcagaccga 20 <210> 1434 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1434 ggagtccatg aagtaactgg 20 <210> 1435 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1435 aggttgcata aagccaggcc 20 <210> 1436 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1436 ccctcttagt gattggtggt 20 <210> 1437 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1437 ggttggcagt cttcaccagt 20 <210> 1438 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1438 gcttgaatgg ataccaatta 20 <210> 1439 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1439 ctcggtcaaa ctaataatac 20 <210> 1440 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1440 ccagttttcg cccgttacct 20 <210> 1441 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1441 gtagctatag gtgtcacata 20 <210> 1442 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1442 gcctcaaata tgtgatgcac 20 <210> 1443 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1443 gaatggcaat acatccgtgt 20 <210> 1444 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1444 tcaatggacc cacatgatca 20 <210> 1445 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1445 tgcataccca gggtaggatt 20 <210> 1446 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1446 tctaatacta caacgatgga 20 <210> 1447 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1447 aaccttccta aaatccccga 20 <210> 1448 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1448 gatataccca gttaatcagt 20 <210> 1449 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1449 ttggcagatg taacctattc 20 <210> 1450 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1450 cgaccctcat cactttttga 20 <210> 1451 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1451 acgggacctc aatactctac 20 <210> 1452 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1452 attcaaggta gccccaatac 20 <210> 1453 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1453 ctggcctttg ggtcggatat 20 <210> 1454 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1454 ccccagataa tgcatagatc 20 <210> 1455 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1455 gggctaagag tcacctgtat 20 <210> 1456 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1456 cccttggcca cctgacttcg 20 <210> 1457 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1457 ttggctcagt gttcacttcg 20 <210> 1458 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1458 gtaaccagac ccaaggcact 20 <210> 1459 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1459 gagatccatg aggtatatac 20 <210> 1460 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1460 gcccagtgcc ctataggtca 20 <210> 1461 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1461 gctatttcat taagtcaccc 20 <210> 1462 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1462 ccatggaatg gctgtcatgc 20 <210> 1463 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1463 ttatcttctt agggtcgact 20 <210> 1464 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1464 agctatccgc ttcccaaggg 20 <210> 1465 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1465 ccctgagatg ctagttgggc 20 <210> 1466 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1466 gtatgtcctt ggaggtgagc 20 <210> 1467 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1467 gcctttcatt ttgggagtgc 20 <210> 1468 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1468 ggcatggaga tccaacctgt 20 <210> 1469 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1469 ggcactgcag gatagccatt 20 <210> 1470 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1470 cgttatccta agaagtgact 20 <210> 1471 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1471 tcaacatgtg ttaacggaac 20 <210> 1472 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1472 gtacctgcag tgcatagagc 20 <210> 1473 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1473 gattgattca gtgctcatgc 20 <210> 1474 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1474 actgcagata ggtaggtgat 20 <210> 1475 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1475 gttggaagct gccagcttag 20 <210> 1476 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1476 actggcctgt ggcagttaac 20 <210> 1477 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1477 gcgctggctc acgcatgctc 20 <210> 1478 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1478 cctagagttt ccttctcccg 20 <210> 1479 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1479 gggatgccaa tgcctccaac 20 <210> 1480 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1480 taaattgccc tgggtgcagc 20 <210> 1481 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1481 gccctttcag gaccaactgg 20 <210> 1482 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1482 gttgggcaaa caagttaccc 20 <210> 1483 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1483 gggaccccaa tttactacgc 20 <210> 1484 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1484 cttcttgcaa ggattggcac 20 <210> 1485 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1485 actgagatgt gtgatactcc 20 <210> 1486 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1486 ccactcaata gaatagtgcc 20 <210> 1487 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1487 cccaattgca aggaccctta 20 <210> 1488 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1488 gaacatgtag ccataatgcc 20 <210> 1489 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1489 gagtggcatc cttaaatcct 20 <210> 1490 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1490 taattggtca agtaaacagc 20 <210> 1491 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1491 tccaccgtta ctgattatct 20 <210> 1492 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1492 caagtcccac catgttaatc 20 <210> 1493 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1493 gttaggatct atttgacagc 20 <210> 1494 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1494 aggcctgctc cgaatgtgtt 20 <210> 1495 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1495 gtgcatggtt atctaatgca 20 <210> 1496 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1496 ttgggtcact aggcacacta 20 <210> 1497 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1497 tgactagttc gataagtttt 20 <210> 1498 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1498 tgtcgagaac tcaaaaggtg 20 <210> 1499 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1499 ctgtatagtt tacccaggca 20 <210> 1500 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1500 cagagtgcat tggcaactcg 20 <210> 1501 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1501 gatcttggta aggcagctcc 20 <210> 1502 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1502 caatttggtc ccattgtagt 20 <210> 1503 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1503 tctatcaagg ctgttattgg 20 <210> 1504 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1504 gctcagttag gttagtgcac 20 <210> 1505 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1505 tctagggctc cagtttatgt 20 <210> 1506 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1506 ctttggttat gtacattgcc 20 <210> 1507 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1507 gcctgtatgt cttgagaaac 20 <210> 1508 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1508 ctcgcttttc acaggagcgc 20 <210> 1509 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1509 tcacagagta gtctattggt 20 <210> 1510 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1510 gtaagtatag atgcctctcc 20 <210> 1511 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1511 gcaaacttta ggagtgtgtt 20 <210> 1512 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1512 ggtattgaca cctccaactg 20 <210> 1513 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1513 atataagggt aatacggacc 20 <210> 1514 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1514 gccccctgcc gtgtgaaaga 20 <210> 1515 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1515 cttcaagact aaggtaggga 20 <210> 1516 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1516 gtatgcgaag cgaacgaagc 20 <210> 1517 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1517 cctaaaaaac ccgtgtacac 20 <210> 1518 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1518 ggtggccttc agtcagtaca 20 <210> 1519 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1519 gcccagactc atgctggtta 20 <210> 1520 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1520 atacttcacc taatagcacc 20 <210> 1521 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1521 ggagttcttt aggttggaac 20 <210> 1522 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1522 gcaactatgg gtggagacat 20 <210> 1523 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1523 tcgggccagg tccaggcgca 20 <210> 1524 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1524 gctgtcatat gggaactacg 20 <210> 1525 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1525 caaacctacg ccaataaaga 20 <210> 1526 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1526 tttatcgctt aaagtagcct 20 <210> 1527 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1527 cgtatatcga ataccctcaa 20 <210> 1528 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1528 gtaagagtta gctattcccc 20 <210> 1529 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1529 cagtaaagag ccacctaagg 20 <210> 1530 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1530 ggcaaggcta aggagtgctc 20 <210> 1531 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1531 gctacccatt agacccatgg 20 <210> 1532 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1532 ggagtccctg tgtcattgga 20 <210> 1533 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1533 ggatgtagcc catcaaccct 20 <210> 1534 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1534 ccagttaatc tctgacatgg 20 <210> 1535 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1535 aggtgatgac acccctacca 20 <210> 1536 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1536 gggtgtctct ttgacaccac 20 <210> 1537 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1537 aggcagtcag ggtaatgcta 20 <210> 1538 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1538 ccttctgtcc caacggagcc 20 <210> 1539 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1539 ctctcgctga ggacacatca 20 <210> 1540 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1540 accacagggt actattctgg 20 <210> 1541 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1541 ctgctctgtt agccgagcat 20 <210> 1542 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1542 gcttgtatgc cccactggag 20 <210> 1543 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1543 gcttgccatg ttttatagac 20 <210> 1544 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1544 ctcaggatcg ctggccattt 20 <210> 1545 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1545 gcctaaaggt agttctccct 20 <210> 1546 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1546 caggagggtg tcaaccagac 20 <210> 1547 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1547 ggcagataac ctccaagtgc 20 <210> 1548 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1548 cacatagacc atagctgaac 20 <210> 1549 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1549 gtctagtatg tctgagtgtc 20 <210> 1550 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1550 gactcgggac atttaggatg 20 <210> 1551 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1551 ataggccacg ctggtcactg 20 <210> 1552 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1552 tcatcctcta tggacccacg 20 <210> 1553 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1553 cccgacttac attacctacc 20 <210> 1554 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1554 atgatctgct gttcagtgcg 20 <210> 1555 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1555 aggccaagtg gtgctcttcc 20 <210> 1556 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1556 attcagatac tagtttaccc 20 <210> 1557 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1557 tctaggtagg ctgagcctca 20 <210> 1558 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1558 ttgtcttgga acatacggat 20 <210> 1559 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1559 gattggcact attttgagcc 20 <210> 1560 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1560 gatactccaa atatgacccg 20 <210> 1561 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1561 aatagaatag tgccagtagg 20 <210> 1562 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1562 ttgcaaggac ccttaagtca 20 <210> 1563 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1563 gtagccataa tgccatagtc 20 <210> 1564 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1564 gcatccttaa atcctggttg 20 <210> 1565 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1565 gcaatatcca tagtgatctg 20 <210> 1566 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1566 cgttactgat tatcttatcc 20 <210> 1567 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1567 cccaccatgt taatcaaggc 20 <210> 1568 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1568 caggtgtata ttccctatcc 20 <210> 1569 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1569 ccgaatgtgt tatttatcct 20 <210> 1570 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1570 ggttatctaa tgcatcatca 20 <210> 1571 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1571 ctaggcacac taaagtgcac 20 <210> 1572 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1572 gatgcaatca cagcaagtac 20 <210> 1573 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1573 gtcgagaact caaaaggtga 20 <210> 1574 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1574 gtttacccag gcaatggctc 20 <210> 1575 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1575 gcaactcgat gttcttgctt 20 <210> 1576 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1576 ttggtaaggc agctcctgac 20 <210> 1577 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1577 tggtcccatt gtagttgtgt 20 <210> 1578 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1578 ctatcaaggc tgttattggt 20 <210> 1579 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1579 gcttctaact aacatgcctc 20 <210> 1580 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1580 gggctccagt ttatgtatcc 20 <210> 1581 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1581 tagcctgcat ggtttacagt 20 <210> 1582 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1582 gggctcttgt tactgagctg 20 <210> 1583 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1583 tttcacagga gcgcacttgg 20 <210> 1584 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1584 gagtagtcta ttggtgttcc 20 <210> 1585 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1585 ccctaccctt gcatgctatg 20 <210> 1586 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1586 ccattgagta tattacctcc 20 <210> 1587 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1587 cctccaactg taatcattga 20 <210> 1588 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1588 gtaatacgga cctcatacag 20 <210> 1589 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1589 actacttgtc ccctgggctt 20 <210> 1590 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1590 cttgcttgta tggtctgatg 20 <210> 1591 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1591 aaaagtaggt ttgcggatgc 20 <210> 1592 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1592 acccgtgtac acagtgggat 20 <210> 1593 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1593 gtcagtacac aagcaggtag 20 <210> 1594 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1594 tcatgctggt tactagggcc 20 <210> 1595 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1595 gttaggccac aagacttaat 20 <210> 1596 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1596 ctcaaacccg tataaagatg 20 <210> 1597 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1597 gacatacaat ggaccaccta 20 <210> 1598 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1598 ggaagttcca acccttactc 20 <210> 1599 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1599 gaatccacta catgggatta 20 <210> 1600 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1600 gactaagccc gaaagttagc 20 <210> 1601 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1601 cgcttaaagt agcctaagga 20 <210> 1602 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1602 cgaataccct caacttcacc 20 <210> 1603 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1603 caaccttgat agcagcttat 20 <210> 1604 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1604 gtgaaactaa gcacatccga 20 <210> 1605 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1605 ggctaaggag tgctctttgt 20 <210> 1606 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1606 cccattagac ccatggctca 20 <210> 1607 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1607 tacaacagtc ccaggctagg 20 <210> 1608 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1608 gtagcccatc aaccctggga 20 <210> 1609 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1609 ctgacatgga ctaataggcc 20 <210> 1610 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1610 gacaccccta ccatggctac 20 <210> 1611 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1611 gtctctttga caccaccaac 20 <210> 1612 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1612 gtaatgctat cttccatgcc 20 <210> 1613 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1613 gtcccaacgg agccttacgc 20 <210> 1614 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1614 cacatcagct gttagcagtc 20 <210> 1615 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1615 actctgtagg ttgacaggac 20 <210> 1616 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1616 ctgttagccg agcattggct 20 <210> 1617 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1617 atgccccact ggagaagtct 20 <210> 1618 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1618 cgtcttcccg caccatgcat 20 <210> 1619 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1619 cgtgtcactt tcaggtcagc 20 <210> 1620 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1620 ggtagttctc ccttctgtca 20 <210> 1621 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1621 gggtgtcaac cagacttcca 20 <210> 1622 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1622 gctcatcaca actgggtggt 20 <210> 1623 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1623 accatagctg aacctgtggc 20 <210> 1624 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1624 gtctgagtgt caggctgtaa 20 <210> 1625 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1625 gtgtgccata ggtttcaggc 20 <210> 1626 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1626 ccacgctggt cactgaaaga 20 <210> 1627 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1627 ccgctcaatg caggacacca 20 <210> 1628 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1628 tgctccatag gtaagatggt 20 <210> 1629 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1629 taggcactgc ctttgttgcg 20 <210> 1630 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1630 gtcgaagaca atataacatc 20 <210> 1631 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1631 atcagggcac atggagttgt 20 <210> 1632 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1632 cccttaggtg ggagtcttcc 20 <210> 1633 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1633 ggctctagac cattgactca 20 <210> 1634 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1634 gtagtgcctc aatgatccac 20 <210> 1635 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1635 ggtaaagtgg actggatgcc 20 <210> 1636 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1636 ctcatgagga ttgcatcaca 20 <210> 1637 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1637 aggaacggcc ctgactgtca 20 <210> 1638 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1638 ccatatcaat aacaattggc 20 <210> 1639 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1639 ggaactccag ccagtgaata 20 <210> 1640 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1640 atgagggaag tctaggtctc 20 <210> 1641 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1641 acataggcac tctactagct 20 <210> 1642 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1642 tatcagtcat agctacacac 20 <210> 1643 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1643 ggtggatgtc tgacttgact 20 <210> 1644 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1644 gctaaagttg tggtctacca 20 <210> 1645 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1645 ttctcatcat cgatccaaac 20 <210> 1646 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1646 taatggctta gctactcacc 20 <210> 1647 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1647 gagaacccac ttgatctatt 20 <210> 1648 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1648 ggacctcagg agattgtaca 20 <210> 1649 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1649 tatagtgtgg atggtatcct 20 <210> 1650 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1650 gtacacaggg atttgagcct 20 <210> 1651 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1651 ggaacattca gctagactag 20 <210> 1652 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1652 taaattggtc tggttacaag 20 <210> 1653 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1653 cctatagatt gggctttaga 20 <210> 1654 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1654 gtctatattt ggtaagacac 20 <210> 1655 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1655 attggtcatc tcgggtatat 20 <210> 1656 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1656 ttcagaccga aggagttcct 20 <210> 1657 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1657 gtaggatcta tggcagttcc 20 <210> 1658 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1658 gttctacaga gtggagccag 20 <210> 1659 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1659 gattggtggt ttattcatcg 20 <210> 1660 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1660 tacccattgc aagttaacta 20 <210> 1661 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1661 tcctaatagt tggaggtggt 20 <210> 1662 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1662 cagcctaata tgtgtcatcc 20 <210> 1663 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1663 cgttacctca attctatggt 20 <210> 1664 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1664 actggagtcc tggttgatgt 20 <210> 1665 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1665 acaaaacggg catgctttat 20 <210> 1666 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1666 gcggataaat tggatttatc 20 <210> 1667 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1667 aggcaatgga cttagtacac 20 <210> 1668 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1668 cccagggtag gattcatggt 20 <210> 1669 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1669 caagtgatga tgttgtatgc 20 <210> 1670 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1670 atccccgaat gggagagatt 20 <210> 1671 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1671 gtgaacgaat actgtggcat 20 <210> 1672 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1672 ccaacctgtc atgggactgc 20 <210> 1673 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1673 taggcctaat ctatgctggg 20 <210> 1674 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1674 tctcaaaaga cattcggtac 20 <210> 1675 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1675 ccatgggcag attgatcacc 20 <210> 1676 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1676 tgcctaaggg agtttgtcac 20 <210> 1677 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1677 atgtttagag gtcaagccct 20 <210> 1678 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1678 tgggtcggat atagctttta 20 <210> 1679 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1679 gacatctgct tatgtagctc 20 <210> 1680 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1680 agttactttg ggacatccca 20 <210> 1681 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1681 gtttggaaca tcatgttagc 20 <210> 1682 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1682 tccaactgat gcatcaagcc 20 <210> 1683 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1683 gcctatatcc aaccagctac 20 <210> 1684 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1684 cgttggaaac ttcaaaggca 20 <210> 1685 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1685 ccttggttgt ggtgaaaccc 20 <210> 1686 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1686 tatcttaact ggtgaactcc 20 <210> 1687 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1687 ggatggttga cctcaaaatt 20 <210> 1688 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1688 tggttaccca tacagtatat 20 <210> 1689 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1689 gcttttcagt caggtacagg 20 <210> 1690 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1690 gacctgtgag ggtgcttagt 20 <210> 1691 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1691 gtttgaccag ctccttgttg 20 <210> 1692 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1692 ttgggagtgc tccacacttc 20 <210> 1693 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1693 gatgccctgg tcctagcttc 20 <210> 1694 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1694 gatagccatt cgatacctgc 20 <210> 1695 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1695 gcttctacat aaccgaagtg 20 <210> 1696 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1696 ctagtgccta ttacaatctg 20 <210> 1697 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1697 catgtgcttt gtggacccat 20 <210> 1698 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1698 gctggacgga cagtgttgct 20 <210> 1699 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1699 ggtgatgaag gtcaagccga 20 <210> 1700 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1700 gtggtttcca gcagggtgta 20 <210> 1701 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1701 actaaagagt actcctacca 20 <210> 1702 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1702 gtaatgattt gccctcctac 20 <210> 1703 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1703 ccagcgggac ctggacaagc 20 <210> 1704 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1704 ggtgtagtgg caagaagttc 20 <210> 1705 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1705 ccccctagct ttccaatggg 20 <210> 1706 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1706 gtctccacat aatcctattg 20 <210> 1707 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1707 acatcccatt aatcatcgct 20 <210> 1708 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1708 tcagattacc tgaaggtgta 20 <210> 1709 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1709 agtggacaga tacggtccgt 20 <210> 1710 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1710 tcagttgtga gtagtgcctc 20 <210> 1711 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1711 gcttaccaga gatggtttcc 20 <210> 1712 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1712 cgtagggcaa aagtaaggat 20 <210> 1713 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1713 gtggcctgaa ggaacggccc 20 <210> 1714 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1714 gaccttcaat tgatcagtct 20 <210> 1715 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1715 cctgtctggt actcccatat 20 <210> 1716 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1716 tcaatatgag ggaagtctag 20 <210> 1717 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1717 ttaactacat aggcactcta 20 <210> 1718 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1718 ctacaccgtg acaaaagagc 20 <210> 1719 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1719 agcacaggtg gatgtctgac 20 <210> 1720 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1720 gtagttgtat cttgaatggg 20 <210> 1721 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1721 catctggacc tcagattgac 20 <210> 1722 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1722 aacgacctaa agacctagca 20 <210> 1723 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1723 cttgagtaac tactcatgac 20 <210> 1724 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1724 gacctatagg acctcaggag 20 <210> 1725 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1725 ctaactttat agtgtggatg 20 <210> 1726 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1726 ccacacatat aggctagcca 20 <210> 1727 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1727 ggtcatcata ttgaaccaat 20 <210> 1728 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1728 gatttcctta ctgagtgagc 20 <210> 1729 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1729 ggtagtctat atttggtaag 20 <210> 1730 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1730 ttattggtca tctcgggtat 20 <210> 1731 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1731 ctatttcaga ccgaaggagt 20 <210> 1732 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1732 gtaactggta ggatctatgg 20 <210> 1733 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1733 tttttagggt agtgtcctga 20 <210> 1734 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1734 cttagtgatt ggtggtttat 20 <210> 1735 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1735 gggatttacc cattgcaagt 20 <210> 1736 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1736 gccatcctaa tagttggagg 20 <210> 1737 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1737 ggttaagtct gctctttcac 20 <210> 1738 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1738 tcgcccgtta cctcaattct 20 <210> 1739 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1739 gctattacac tggagtcctg 20 <210> 1740 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1740 caatacaaaa cgggcatgct 20 <210> 1741 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1741 gatcattccc tgtggtaaag 20 <210> 1742 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1742 gcttaggcaa tggacttagt 20 <210> 1743 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1743 catacccagg gtaggattca 20 <210> 1744 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1744 ataacactaa cgatgaactc 20 <210> 1745 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1745 cctaaaatcc ccgaatggga 20 <210> 1746 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1746 cccagttaat cagtgaacga 20 <210> 1747 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1747 atgttccaac ctgtcatggg 20 <210> 1748 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1748 gatgagatta ggcctaatct 20 <210> 1749 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1749 ccatctacta ttaatgagct 20 <210> 1750 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1750 tcaccatggg cagattgatc 20 <210> 1751 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1751 caaaacatgt tctgacctcg 20 <210> 1752 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1752 ggcctttggg tcggatatag 20 <210> 1753 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1753 cgtcaaactg acatctgctt 20 <210> 1754 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1754 agttaacacc tatcaagttg 20 <210> 1755 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1755 ggccacctga cttcggccca 20 <210> 1756 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1756 gacttccaac tgatgcatca 20 <210> 1757 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1757 gacccttctg tgaaagccta 20 <210> 1758 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1758 gactgcatct caatcctatg 20 <210> 1759 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1759 gcccatatgc ttgaacaatt 20 <210> 1760 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1760 gtatcttaac tggtgaactc 20 <210> 1761 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1761 gcagtttgga tggttgacct 20 <210> 1762 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1762 gggtcgactg atggttaccc 20 <210> 1763 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1763 ataggagctg aatagtaggg 20 <210> 1764 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1764 tcaaagacct gtgagggtgc 20 <210> 1765 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1765 ggtgagctgt ttgaccagct 20 <210> 1766 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1766 tcattttggg agtgctccac 20 <210> 1767 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1767 ggagatccaa cctgtgtgga 20 <210> 1768 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1768 ctgcaggata gccattcgat 20 <210> 1769 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1769 cattattcaa ttaagggtgg 20 <210> 1770 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1770 catgtgttaa cggaactgag 20 <210> 1771 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1771 gtgcatagag cagactgtac 20 <210> 1772 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1772 ggttttgaga gctggacgga 20 <210> 1773 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1773 ataggtaggt gatgaaggtc 20 <210> 1774 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1774 gctgccagct tagagaatct 20 <210> 1775 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1775 gttaactaaa gagtactcct 20 <210> 1776 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1776 gtaggagata ggcagtgcat 20 <210> 1777 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1777 aattatactg tcctacttcg 20 <210> 1778 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1778 gtaccccaga aatagcccat 20 <210> 1779 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1779 catcactagc ctagtgatct 20 <210> 1780 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1780 gggtgctgtc aactgtccca 20 <210> 1781 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1781 ggcaaagtac atactgatcc 20 <210> 1782 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1782 cctgtgcggt agcacttgcc 20 <210> 1783 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1783 gggccaagca cataggtatc 20 <210> 1784 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1784 cgtgcaaaac aagtttcgca 20 <210> 1785 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1785 gaccacgata actgtagcgc 20 <210> 1786 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1786 tcctggcaag tatgctagtc 20 <210> 1787 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1787 actgatccat tagataggct 20 <210> 1788 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1788 agaacacttc gccgctgatt 20 <210> 1789 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1789 aacataaggt tcaaaagccg 20 <210> 1790 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1790 catagatgat cccataatag 20 <210> 1791 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1791 ccgaaagcac tttgcatgag 20 <210> 1792 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1792 atccttgatc cagacaagtc 20 <210> 1793 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1793 atcatacagg catctcagcc 20 <210> 1794 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1794 tgtcactgag ggatccccaa 20 <210> 1795 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1795 ggattcaata gtgtaggtga 20 <210> 1796 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1796 gtacaatgca tgtgggcctc 20 <210> 1797 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1797 actggcatat tccgattata 20 <210> 1798 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1798 cgtattggac ctttcaatga 20 <210> 1799 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1799 attgaagctg gcaatatgtc 20 <210> 1800 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1800 gcatgtacaa acgggctatg 20 <210> 1801 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1801 ggaatcttgt agaggattgg 20 <210> 1802 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1802 tcagcactta ggtagttcac 20 <210> 1803 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1803 tgtcttttga cacgctgact 20 <210> 1804 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1804 gtactcttgc ccatggatgg 20 <210> 1805 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1805 cccctgtggc ttataggtgg 20 <210> 1806 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1806 ggatgaacct gcttcacaca 20 <210> 1807 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1807 cagatttgcc aggtaaagcg 20 <210> 1808 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1808 aactatcctg catccgaggc 20 <210> 1809 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1809 ggtcaaccaa tttgctattc 20 <210> 1810 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1810 ggtcttggga ttatagtttg 20 <210> 1811 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1811 ggagttccta actctcaatc 20 <210> 1812 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1812 tctactgagg aacccatcac 20 <210> 1813 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1813 cgttgcataa catgtgtatt 20 <210> 1814 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1814 tacacctgca acaagccatc 20 <210> 1815 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1815 gagcaaatcg gcaaaggcat 20 <210> 1816 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1816 ccaagtggct tgtggtgaaa 20 <210> 1817 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1817 gaactacgaa taattgcatg 20 <210> 1818 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1818 caatggttta gtgtcatatg 20 <210> 1819 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1819 agtagctgtt taggctggac 20 <210> 1820 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1820 ttgccctgcc actcccgtgg 20 <210> 1821 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1821 gggatatatc acttggagct 20 <210> 1822 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1822 cagattaggt atggaggcca 20 <210> 1823 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1823 acggattaga ttctccaaca 20 <210> 1824 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1824 aggacacatc aagctagcta 20 <210> 1825 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1825 aagccctttg ctttttcggg 20 <210> 1826 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1826 gtgttttgac ctaactggcc 20 <210> 1827 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1827 cgtgggtatg gttttcctct 20 <210> 1828 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1828 tccaacgagt gataattcac 20 <210> 1829 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1829 aattgatgca taagtaaggc 20 <210> 1830 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1830 ataggcactt cgggcaaata 20 <210> 1831 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1831 ggatttaggt gctacagtca 20 <210> 1832 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1832 gttagcccag gtgatcagct 20 <210> 1833 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1833 attgcaacta ataaagggtc 20 <210> 1834 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1834 gctctcatgt gagagtatga 20 <210> 1835 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1835 tcatgaattc aggttgcccc 20 <210> 1836 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1836 ctttggttgg aagttagacc 20 <210> 1837 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1837 ctgcttattg caggcctagc 20 <210> 1838 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1838 cagttgagaa cggtattgag 20 <210> 1839 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1839 gtctgtcttt agggtcaccc 20 <210> 1840 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1840 gctttaggat ggtgtggatc 20 <210> 1841 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1841 ctctcactga ctagctttcg 20 <210> 1842 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1842 cttaccgtct ttaggaactt 20 <210> 1843 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1843 ggacagcaca acccccgtgc 20 <210> 1844 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1844 ccctacaatg catacccaac 20 <210> 1845 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1845 gagttataca cggaacccac 20 <210> 1846 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1846 gtccaagaca tgctagggac 20 <210> 1847 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1847 caatctagtt agaccaggca 20 <210> 1848 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1848 atggactgcc ggcctggagc 20 <210> 1849 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1849 gtgaactact tggagacctt 20 <210> 1850 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1850 acgcaactga gacaatccat 20 <210> 1851 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1851 gtggctgtgc tggatattac 20 <210> 1852 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1852 gagcaaaatg gtcagtaccc 20 <210> 1853 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1853 gataggtcag tcactcactg 20 <210> 1854 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1854 ggatgcattg gtgtcaagag 20 <210> 1855 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1855 ggtttacaca tgataggaac 20 <210> 1856 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1856 aacaacggtt gcagggacag 20 <210> 1857 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1857 ccccgtgtac agtaagggcc 20 <210> 1858 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1858 gtcttagtgc caaatatcca 20 <210> 1859 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1859 tatttagacc acgataactg 20 <210> 1860 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1860 tccctcttgt agatcctggc 20 <210> 1861 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1861 gagatatgat tagtactgga 20 <210> 1862 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1862 gagatagaac acttcgccgc 20 <210> 1863 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1863 gtgattaggc ggccgggcgc 20 <210> 1864 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1864 cttatggaga cttatatacc 20 <210> 1865 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1865 gggtagaaga ctagcataca 20 <210> 1866 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1866 gtacttatcc ttgatccaga 20 <210> 1867 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1867 agcacaagat tggttccatt 20 <210> 1868 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1868 gggtactatg ttgtcactga 20 <210> 1869 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1869 atgaaccatg gagtctctat 20 <210> 1870 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1870 ggctttatac tttacccaac 20 <210> 1871 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1871 gtagataact ttaccttgac 20 <210> 1872 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1872 gtttataggg tggttggttc 20 <210> 1873 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1873 gggttacttt ccaatagagt 20 <210> 1874 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1874 aggcatgtac aaacgggcta 20 <210> 1875 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1875 gttctggaat cttgtagagg 20 <210> 1876 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1876 cccattcagc acttaggtag 20 <210> 1877 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1877 ctgctcaaat ctgcgaatag 20 <210> 1878 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1878 gaggatggtg tgtatgttat 20 <210> 1879 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1879 tcccacaagg tactcttgcc 20 <210> 1880 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1880 gcatcccctg tggcttatag 20 <210> 1881 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1881 tcagttagtc aggttaggga 20 <210> 1882 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1882 agctattgca gctatgggtt 20 <210> 1883 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1883 gttcaaccat cgagatgatc 20 <210> 1884 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1884 gatagggttt aggtcaacca 20 <210> 1885 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1885 atctggtctt gggattatag 20 <210> 1886 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1886 cttaggagtt cctaactctc 20 <210> 1887 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1887 gttttggaga ttgtgttacg 20 <210> 1888 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1888 ggagccaggt agagttaacg 20 <210> 1889 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1889 ggatagttgt gaacaacttc 20 <210> 1890 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1890 cattgaatga gggcccaaac 20 <210> 1891 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1891 ggacttgtct tatggctgcc 20 <210> 1892 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1892 tgattattca gagaactacg 20 <210> 1893 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1893 cgttggcatt taagtctgag 20 <210> 1894 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1894 ctgggttgag actattcagg 20 <210> 1895 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1895 ccattgaaga aaaacccgcg 20 <210> 1896 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1896 gcactactgt aagggtcatg 20 <210> 1897 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1897 acaagggtag tgttacactg 20 <210> 1898 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1898 caatggtaat cgcatatact 20 <210> 1899 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1899 gactaatcct cttaagttca 20 <210> 1900 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1900 aggtactgta agccctttgc 20 <210> 1901 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1901 aacttttaca cgctagtggg 20 <210> 1902 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1902 ccctttgttc atactgaacg 20 <210> 1903 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1903 agcttccctc caacgagtga 20 <210> 1904 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1904 ggcccaaggg aattgatgca 20 <210> 1905 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1905 aggaataggc acttcgggca 20 <210> 1906 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1906 ggaacccagg atttaggtgc 20 <210> 1907 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1907 ggtcatagga gtgttagccc 20 <210> 1908 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1908 ggttggattg ctttattgca 20 <210> 1909 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1909 gcctgctctc atgtgagagt 20 <210> 1910 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1910 cgcttggctg acatttaggg 20 <210> 1911 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1911 accgagctca agaactgtga 20 <210> 1912 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1912 tggcctgctt attgcaggcc 20 <210> 1913 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1913 gttttcagtt gagaacggta 20 <210> 1914 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1914 gggacctcct tatattcacc 20 <210> 1915 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1915 cccctgcttt aggatggtgt 20 <210> 1916 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1916 ggtcccccca gaaggcttga 20 <210> 1917 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1917 tattcttacc gtctttagga 20 <210> 1918 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1918 ggatggagct gttgtggcat 20 <210> 1919 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1919 gcattaccct acaatgcata 20 <210> 1920 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1920 gcatttgaga gttatacacg 20 <210> 1921 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1921 gggccttata gaccatacca 20 <210> 1922 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1922 ggagacaatc tagttagacc 20 <210> 1923 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1923 gcacaaatgg actgccggcc 20 <210> 1924 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1924 gagagtcata ctcctgacag 20 <210> 1925 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1925 ctccgggctc accacctggt 20 <210> 1926 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1926 tctatacact gctgttgacg 20 <210> 1927 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1927 gcttgctaaa cctgtccatt 20 <210> 1928 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1928 ctggatggta taaattgccc 20 <210> 1929 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1929 gttgccgctt tggtgaacct 20 <210> 1930 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1930 gtgcactgat acagttgggc 20 <210> 1931 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1931 ccatcaagta ggccagtcac 20 <210> 1932 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1932 ggaataaccc atacccccca 20 <210> 1933 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1933 gcatgactcc taattgctgt 20 <210> 1934 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1934 gagctcagtc ttcactagtt 20 <210> 1935 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1935 gtcaggcacc agattgctca 20 <210> 1936 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1936 atgatcatac tggagccagg 20 <210> 1937 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1937 acctaccaga gtggcatcct 20 <210> 1938 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1938 acgctgtgtg aatcaaaagc 20 <210> 1939 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1939 agtgttctta catccaccgt 20 <210> 1940 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1940 catgccaatc gcatgcaagc 20 <210> 1941 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1941 gtcaggagtt aactatgaac 20 <210> 1942 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1942 caccagttag gcctgctccg 20 <210> 1943 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1943 cgtttccaca gccaggctta 20 <210> 1944 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1944 agtcttgggt cactaggcac 20 <210> 1945 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1945 ccaatatttt gactagttcg 20 <210> 1946 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1946 tttagtatgt cgagaactca 20 <210> 1947 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1947 tgaaacctgt atagtttacc 20 <210> 1948 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1948 ctaaccatag acagagtgca 20 <210> 1949 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1949 catcatgatc ttggtaaggc 20 <210> 1950 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1950 gaccccacaa tttggtccca 20 <210> 1951 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1951 gactatctca gcactaggga 20 <210> 1952 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1952 gccctgtagt atgtggatac 20 <210> 1953 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1953 ctcgggtata taaattaatg 20 <210> 1954 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1954 ggatctagaa tgattggttg 20 <210> 1955 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1955 gggctgctgt ttgagtcccc 20 <210> 1956 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1956 agatactcac tcgcttttca 20 <210> 1957 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1957 acgctccttc atttcatgca 20 <210> 1958 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1958 gctgtaagta tagatgcctc 20 <210> 1959 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1959 attagttgac tctataaacg 20 <210> 1960 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1960 aagtttggta ttgacacctc 20 <210> 1961 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1961 cttgatataa gggtaatacg 20 <210> 1962 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1962 ggctcaggca aagtagcttc 20 <210> 1963 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1963 gccatcttca agactaaggt 20 <210> 1964 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1964 cgaaaaatag tatgcgaagc 20 <210> 1965 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1965 ggagacccta aaaaacccgt 20 <210> 1966 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1966 cctataggtg gccttcagtc 20 <210> 1967 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1967 ggcaagccca gactcatgct 20 <210> 1968 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1968 cgtcaacact atagatgaat 20 <210> 1969 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1969 ccactcatgt acatgagatc 20 <210> 1970 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1970 ggcaagcaac tatgggtgga 20 <210> 1971 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1971 gtttacttcg ggccaggtcc 20 <210> 1972 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1972 acccctagga ataatgttgc 20 <210> 1973 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1973 agcgatacaa acctacgcca 20 <210> 1974 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1974 ggcaagtttt tatcgcttaa 20 <210> 1975 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1975 agtattttag ccgggatacg 20 <210> 1976 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1976 acgggttcct atttgtcagg 20 <210> 1977 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1977 gtgagcttta ctctgcaata 20 <210> 1978 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1978 gccttattgg agagagaact 20 <210> 1979 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1979 tcagtgctac ccattagacc 20 <210> 1980 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1980 catacatgga ggagtccctg 20 <210> 1981 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1981 tcctaaggat gtagcccatc 20 <210> 1982 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1982 cgcatccagt taatctctga 20 <210> 1983 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1983 gtcccagttg gattaaggtg 20 <210> 1984 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1984 ctgtacagga gggtgtctct 20 <210> 1985 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1985 tagtctaagg cagtcagggt 20 <210> 1986 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1986 atctagactc tgcctggtta 20 <210> 1987 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1987 ggacactctc gctgaggaca 20 <210> 1988 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1988 ggcactatga ccacagggta 20 <210> 1989 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1989 tctgctctgt tagccgagca 20 <210> 1990 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1990 gcacaatgct tgtatgcccc 20 <210> 1991 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1991 gtgcccttac tgttaaatcc 20 <210> 1992 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1992 tttgctcagg atcgctggcc 20 <210> 1993 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1993 agcctctgcc taaaggtagt 20 <210> 1994 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1994 cgtgattgca aagtccaagg 20 <210> 1995 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1995 cagtagtggt atcaaatctg 20 <210> 1996 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1996 tccagcacat agaccatagc 20 <210> 1997 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1997 ggtggaaagt ctagtatgtc 20 <210> 1998 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1998 gacccatgga aagactcggg 20 <210> 1999 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 1999 gtttcccata ggccacgctg 20 <210> 2000 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2000 agtggttgct atcctgctaa 20 <210> 2001 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2001 acgcaagtcc tcctccgggc 20 <210> 2002 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2002 tcaagggaac taactcctcc 20 <210> 2003 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2003 gattgatcat gttatgccct 20 <210> 2004 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2004 ggtggattgg agttgctaca 20 <210> 2005 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2005 tgggacacat atgttgccgc 20 <210> 2006 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2006 ctgaagcaaa gcttataggc 20 <210> 2007 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2007 tgacactgag taatctgcga 20 <210> 2008 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2008 tgtaagattc ccccaagggt 20 <210> 2009 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2009 ggtgggatta catctcttat 20 <210> 2010 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2010 cgtgatattc atgttgtctg 20 <210> 2011 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2011 cgaagccaaa ggtacttgag 20 <210> 2012 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2012 gcttgcactc catcatataa 20 <210> 2013 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2013 aggaccagcc agtctagttt 20 <210> 2014 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2014 ggtctcacgc tgtgtgaatc 20 <210> 2015 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2015 ggagtcaagt tggttaatag 20 <210> 2016 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2016 gggcgaaagt atatcaggca 20 <210> 2017 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2017 ggctgtcaat gctgatatat 20 <210> 2018 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2018 ggagttcacc agttaggcct 20 <210> 2019 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2019 accctcccaa caaataagcg 20 <210> 2020 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2020 agcaagtctt gggtcactag 20 <210> 2021 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2021 ggcatcaatc aacaagcacc 20 <210> 2022 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2022 gctttagtat gtcgagaact 20 <210> 2023 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2023 gtggatggta tcctggtcaa 20 <210> 2024 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2024 gcatgattct aaccatagac 20 <210> 2025 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2025 gtactcatca tgatcttggt 20 <210> 2026 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2026 ggaatagggc tctgcttatt 20 <210> 2027 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2027 cctcgaggat agtttcactg 20 <210> 2028 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2028 catctcgggt atataaatta 20 <210> 2029 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2029 tgttggatct agaatgattg 20 <210> 2030 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2030 gtatgggctg ctgtttgagt 20 <210> 2031 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2031 ctgcagagat actcactcgc 20 <210> 2032 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2032 ttgatacgct ccttcatttc 20 <210> 2033 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2033 atgctgtaag tatagatgcc 20 <210> 2034 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2034 cgttgaatat tagttgactc 20 <210> 2035 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2035 ggtgttgtat gataatgtgt 20 <210> 2036 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2036 caatagtagt gatgacttcc 20 <210> 2037 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2037 agatggagct tgagccatcc 20 <210> 2038 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2038 gccccacagt agaaatgtgg 20 <210> 2039 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2039 agtcaacaag acaactcgat 20 <210> 2040 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2040 cgttattcag tctcagggag 20 <210> 2041 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2041 ctttcaccta taggtggcct 20 <210> 2042 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2042 gagtaatgga cttctggtct 20 <210> 2043 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2043 gtgtgaggga atctaagatc 20 <210> 2044 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2044 ggtgccacac catcaaaaga 20 <210> 2045 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2045 gctgcagtgg taccacagac 20 <210> 2046 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2046 aagaagttta cttcgggcca 20 <210> 2047 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2047 tcgggagttg ttagtccaag 20 <210> 2048 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2048 gctcccaaac aactaatagt 20 <210> 2049 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2049 tcaaaatcac gaaaggcggg 20 <210> 2050 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2050 ttagaagtat tttagccggg 20 <210> 2051 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2051 ggtaggtaac tacgggttcc 20 <210> 2052 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2052 cacccctgta aacagtgagc 20 <210> 2053 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2053 ctgctcaagc cttattggag 20 <210> 2054 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2054 gtggaatcag tgctacccat 20 <210> 2055 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2055 agctgggcac tcatacatac 20 <210> 2056 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2056 agcctcctaa ggatgtagcc 20 <210> 2057 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2057 atggtcctcg catccagtta 20 <210> 2058 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2058 cagcactgtc ccagttggat 20 <210> 2059 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2059 gttgattcac tgcacactgt 20 <210> 2060 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2060 ggtatattag tctaaggcag 20 <210> 2061 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2061 gcgaagcctt ctcaaagact 20 <210> 2062 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2062 gggccgcctc tgttattgtg 20 <210> 2063 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2063 gaactgtggg cactatgacc 20 <210> 2064 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2064 cctttggagc tttgactggc 20 <210> 2065 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2065 cgatttcctg ccagtggctg 20 <210> 2066 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2066 ctactgtgcc cttactgtta 20 <210> 2067 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2067 gaagacttag gtctcaagct 20 <210> 2068 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2068 gtagtcatgt agaacagcac 20 <210> 2069 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2069 ccaccgtgat tgcaaagtcc 20 <210> 2070 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2070 gggcacagta gtggtatcaa 20 <210> 2071 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2071 agagctgtcc taaggcaatt 20 <210> 2072 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2072 cttgacatac aggataggtg 20 <210> 2073 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2073 ttggtaaatt agacccatgg 20 <210> 2074 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2074 gatgtatgtt tcccataggc 20 <210> 2075 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2075 aagggtctta gtgccaaata 20 <210> 2076 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2076 atgctagtca ctcattgaga 20 <210> 2077 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2077 tgatccatta gataggctat 20 <210> 2078 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2078 tctcacgctg tgtgaatcaa 20 <210> 2079 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2079 agggaagtct aggtctcacg 20 <210> 2080 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2080 gacccttatg gagacttata 20 <210> 2081 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2081 gtggactcca cacacctact 20 <210> 2082 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2082 gcaagcaaag actacaccgt 20 <210> 2083 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2083 atattcccta tccagggtag 20 <210> 2084 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2084 aggtgtatat tccctatcca 20 <210> 2085 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2085 tgatattgca gtgggatggc 20 <210> 2086 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2086 gcatggttat ctaatgcatc 20 <210> 2087 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2087 gagggatccc caaatagagc 20 <210> 2088 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2088 atcacagttg cttgaccctt 20 <210> 2089 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2089 tgatctatta tgagggcatc 20 <210> 2090 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2090 ttccctaata tagggcagat 20 <210> 2091 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2091 ctataggacc tcaggagatt 20 <210> 2092 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2092 ctcaagacct ataggacctc 20 <210> 2093 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2093 tagtgtggat ggtatcctgg 20 <210> 2094 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2094 tagggtggtt ggttcaaaat 20 <210> 2095 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2095 cacacatata ggctagccaa 20 <210> 2096 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2096 tgggttactt tccaatagag 20 <210> 2097 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2097 cttaggtagt tcacaactct 20 <210> 2098 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2098 cctgtagtat gtggatactg 20 <210> 2099 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2099 ggatggtgtg tatgttatga 20 <210> 2100 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2100 gtagtctatt ggtgttcctt 20 <210> 2101 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2101 atacgctcct tcatttcatg 20 <210> 2102 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2102 gaattcaatg gacccacatg 20 <210> 2103 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2103 gggtaggatt catggtccaa 20 <210> 2104 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2104 taatagactg cgattataca 20 <210> 2105 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2105 ggcctaatct atgctgggcc 20 <210> 2106 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2106 tgagattagg cctaatctat 20 <210> 2107 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2107 gattaggtat ggaggccatg 20 <210> 2108 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2108 ccccaataca gattcagtgg 20 <210> 2109 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2109 tcaaggtagc cccaatacag 20 <210> 2110 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2110 caagaggtac tgtaagccct 20 <210> 2111 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2111 tgttttgacc taactggcct 20 <210> 2112 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2112 gctaagagtc acctgtatcc 20 <210> 2113 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2113 aaggtattaa ggcccttggc 20 <210> 2114 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2114 ggtgatcagc tcaacacccc 20 <210> 2115 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2115 aggagtgtta gcccaggtga 20 <210> 2116 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2116 gggtcatagg agtgttagcc 20 <210> 2117 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2117 aaggtgatga cacccctacc 20 <210> 2118 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2118 agctatttca ttaagtcacc 20 <210> 2119 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2119 gtatattagt ctaaggcagt 20 <210> 2120 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2120 tattatcttc ttagggtcga 20 <210> 2121 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2121 tgtgtaccga gctcaagaac 20 <210> 2122 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2122 agtctgtctc tgtgtaccga 20 <210> 2123 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2123 gacactctcg ctgaggacac 20 <210> 2124 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2124 gccgcctctg ttattgtgat 20 <210> 2125 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2125 aaattgggcc gcctctgtta 20 <210> 2126 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2126 ctgtaggttg acaggacatg 20 <210> 2127 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2127 tgagggtgct tagtgaactg 20 <210> 2128 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2128 gagtctgtct ttagggtcac 20 <210> 2129 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2129 cgatacctgc ttttgtgaca 20 <210> 2130 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2130 atagccattc gatacctgct 20 <210> 2131 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2131 actgcaggat agccattcga 20 <210> 2132 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2132 tatgaatgcc accgtgattg 20 <210> 2133 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2133 aactacatag gcactctact 20 <210> 2134 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2134 aacattcagc tagactagtt 20 <210> 2135 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2135 atgagacccc acaatttggt 20 <210> 2136 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2136 atagaggccc tcttgtttca 20 <210> 2137 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2137 caattgtcag acttattgag 20 <210> 2138 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2138 gaactcccac aaggtactct 20 <210> 2139 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2139 ctgtagtatg cattgacaag 20 <210> 2140 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2140 tactagggcc agagaatcca 20 <210> 2141 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2141 aagccactca tgtacatgag 20 <210> 2142 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2142 aaactgggtt gagactattc 20 <210> 2143 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2143 ctgcagtggt accacagacc 20 <210> 2144 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2144 tgactacaca tcttgtatac 20 <210> 2145 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2145 ctaggcagct ctttgtaggc 20 <210> 2146 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2146 ccctataggt caaaaatgcc 20 <210> 2147 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2147 tcagtcaggt acaggtgttg 20 <210> 2148 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2148 gtcaaagacc tgtgagggtg 20 <210> 2149 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2149 ggtctttgca gttaagttat 20 <210> 2150 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2150 gggtcttagt gccaaatatc 20 <210> 2151 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2151 gaagtctagg tctcacgctg 20 <210> 2152 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2152 tacataggca ctctactagc 20 <210> 2153 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2153 cccttatgga gacttatata 20 <210> 2154 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2154 tgaagatttg acccttatgg 20 <210> 2155 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2155 aagcaaagac tacaccgtga 20 <210> 2156 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2156 atccagggta gaagactagc 20 <210> 2157 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2157 gtgtatattc cctatccagg 20 <210> 2158 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2158 ggatggctgt caatgctgat 20 <210> 2159 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2159 acaagtctac taccaataag 20 <210> 2160 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2160 attctcatca tcgatccaaa 20 <210> 2161 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2161 cacagttgct tgacccttaa 20 <210> 2162 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2162 gattcaatag tgtaggtgac 20 <210> 2163 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2163 cctaatatag ggcagatgat 20 <210> 2164 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2164 aggacctcag gagattgtac 20 <210> 2165 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2165 caagacctat aggacctcag 20 <210> 2166 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2166 agactatcct ggtatgactg 20 <210> 2167 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2167 tgattgacta cttcaacctg 20 <210> 2168 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2168 cgtttatagg gtggttggtt 20 <210> 2169 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2169 cagctagact agttgaaatc 20 <210> 2170 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2170 gagaccccac aatttggtcc 20 <210> 2171 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2171 aggcagttgt gatagtcaac 20 <210> 2172 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2172 ccattcagca cttaggtagt 20 <210> 2173 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2173 tatgccctgt agtatgtgga 20 <210> 2174 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2174 ttttattggt catctcgggt 20 <210> 2175 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2175 tcagacttat tgaggatggt 20 <210> 2176 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2176 actggtagga tctatggcag 20 <210> 2177 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2177 cacagagtag tctattggtg 20 <210> 2178 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2178 gtctccctct tagtgattgg 20 <210> 2179 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2179 agtggttgcc ttagtattac 20 <210> 2180 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2180 tgtaaatggc ctgactaggc 20 <210> 2181 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2181 ctaggaccag ttggttcact 20 <210> 2182 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2182 aatggaccac ctaagacctc 20 <210> 2183 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2183 taatctatgc tgggccccaa 20 <210> 2184 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2184 agattaggcc taatctatgc 20 <210> 2185 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2185 gaccctcatc actttttgac 20 <210> 2186 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2186 gcccggcaag agattcactt 20 <210> 2187 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2187 aggtagcccc aatacagatt 20 <210> 2188 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2188 agggccatgt taaaggcctc 20 <210> 2189 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2189 gacctaactg gcctttgggt 20 <210> 2190 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2190 tatgtggaat cagtgctacc 20 <210> 2191 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2191 tatacaaggt attaaggccc 20 <210> 2192 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2192 gcagctcttt gtaggcccaa 20 <210> 2193 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2193 gactaatagg cctttctaca 20 <210> 2194 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2194 gagtgttagc ccaggtgatc 20 <210> 2195 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2195 tcataggagt gttagcccag 20 <210> 2196 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2196 gtgatgacac ccctaccatg 20 <210> 2197 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2197 gattaaggtg atgacacccc 20 <210> 2198 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2198 caccaacctt aaatagtagg 20 <210> 2199 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2199 tattagtcta aggcagtcag 20 <210> 2200 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2200 ggagccttac gcttggctga 20 <210> 2201 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2201 tgtaccgagc tcaagaactg 20 <210> 2202 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2202 tgtctctgtg taccgagctc 20 <210> 2203 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2203 cactctcgct gaggacacat 20 <210> 2204 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2204 cgcctctgtt attgtgatat 20 <210> 2205 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2205 attgggccgc ctctgttatt 20 <210> 2206 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2206 tgtagaaatt gggccgcctc 20 <210> 2207 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2207 gtaggttgac aggacatgct 20 <210> 2208 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2208 gggtgcttag tgaactgtgg 20 <210> 2209 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2209 agacctgtga gggtgcttag 20 <210> 2210 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2210 gtctaccagg gtggtattat 20 <210> 2211 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2211 tatatactcc aggttgtgga 20 <210> 2212 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2212 agccattcga tacctgcttt 20 <210> 2213 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2213 gcaggatagc cattcgatac 20 <210> 2214 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2214 gaatgccacc gtgattgcaa 20 <210> 2215 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2215 gcacatagac catagctgaa 20 <210> 2216 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2216 caatagaata gtgccagtag 20 <210> 2217 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2217 tgatcatact ggagccaggt 20 <210> 2218 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2218 cacgctgtgt gaatcaaaag 20 <210> 2219 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2219 gtgtttatcc aaaccaaggg 20 <210> 2220 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2220 ctcccacaag gtactcttgc 20 <210> 2221 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2221 ggatgtcagt tcagatgaac 20 <210> 2222 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2222 caacatagat cctctgttag 20 <210> 2223 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2223 ctgctcccta agcttagata 20 <210> 2224 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2224 agtaaagagc cacctaaggg 20 <210> 2225 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2225 ggtcttagtg ccaaatatcc 20 <210> 2226 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2226 aatagtgcca gtaggactta 20 <210> 2227 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2227 caagtatgct agtcactcat 20 <210> 2228 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2228 tctaggtctc acgctgtgtg 20 <210> 2229 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2229 atagtgttct tacatccacc 20 <210> 2230 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2230 ccttatggag acttatatac 20 <210> 2231 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2231 gaagatttga cccttatgga 20 <210> 2232 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2232 agcaaagact acaccgtgac 20 <210> 2233 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2233 tgtatattcc ctatccaggg 20 <210> 2234 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2234 gatggctgtc aatgctgata 20 <210> 2235 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2235 tcatcatcga tccaaacaag 20 <210> 2236 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2236 acagttgctt gacccttaat 20 <210> 2237 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2237 tcaatagtgt aggtgacatg 20 <210> 2238 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2238 atgtgggcct ctattaagat 20 <210> 2239 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2239 gacctcagga gattgtacaa 20 <210> 2240 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2240 aagacctata ggacctcagg 20 <210> 2241 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2241 gactatcctg gtatgactgt 20 <210> 2242 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2242 gattgactac ttcaacctga 20 <210> 2243 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2243 tttatagggt ggttggttca 20 <210> 2244 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2244 ggatttacca cacatatagg 20 <210> 2245 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2245 ggtaaggcag ctcctgacaa 20 <210> 2246 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2246 agaccccaca atttggtccc 20 <210> 2247 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2247 gcacttaggt agttcacaac 20 <210> 2248 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2248 tttattggtc atctcgggta 20 <210> 2249 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2249 cagacttatt gaggatggtg 20 <210> 2250 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2250 ttaggacaag tcttatagag 20 <210> 2251 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2251 ctggtaggat ctatggcagt 20 <210> 2252 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2252 acagagtagt ctattggtgt 20 <210> 2253 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2253 tctccctctt agtgattggt 20 <210> 2254 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2254 ggcctgacta ggcattgaat 20 <210> 2255 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2255 tcatgtgcat acccagggta 20 <210> 2256 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2256 taggaccagt tggttcactg 20 <210> 2257 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2257 atgttaatag actgcgatta 20 <210> 2258 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2258 gctccctaag cttagatata 20 <210> 2259 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2259 atggaccacc taagacctca 20 <210> 2260 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2260 aatctatgct gggccccaat 20 <210> 2261 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2261 gattaggcct aatctatgct 20 <210> 2262 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2262 tccatctact attaatgagc 20 <210> 2263 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2263 gattaggcag cttcactact 20 <210> 2264 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2264 gtagccccaa tacagattca 20 <210> 2265 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2265 acctaactgg cctttgggtc 20 <210> 2266 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2266 tcaaggtgtt ttgacctaac 20 <210> 2267 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2267 gatgggctaa gagtcacctg 20 <210> 2268 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2268 tacaaggtat taaggccctt 20 <210> 2269 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2269 ctctttgtag gcccaaggga 20 <210> 2270 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2270 aataggcact tcgggcaaat 20 <210> 2271 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2271 agtgttagcc caggtgatca 20 <210> 2272 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2272 cataggagtg ttagcccagg 20 <210> 2273 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2273 tgatgacacc cctaccatgg 20 <210> 2274 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2274 attaaggtga tgacacccct 20 <210> 2275 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2275 attagtctaa ggcagtcagg 20 <210> 2276 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2276 gtaggtatat tagtctaagg 20 <210> 2277 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2277 gtaccgagct caagaactgt 20 <210> 2278 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2278 tctctgtgta ccgagctcaa 20 <210> 2279 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2279 actctcgctg aggacacatc 20 <210> 2280 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2280 aatgaggaca ctctcgctga 20 <210> 2281 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2281 ttgggccgcc tctgttattg 20 <210> 2282 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2282 gtagaaattg ggccgcctct 20 <210> 2283 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2283 taggttgaca ggacatgctg 20 <210> 2284 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2284 gcttagtgaa ctgtgggcac 20 <210> 2285 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2285 acctgtgagg gtgcttagtg 20 <210> 2286 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2286 ctaccagggt ggtattataa 20 <210> 2287 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2287 caggatagcc attcgatacc 20 <210> 2288 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2288 tgccaccgtg attgcaaagt 20 <210> 2289 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2289 acatagacca tagctgaacc 20 <210> 2290 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2290 ggcatcctta aatcctggtt 20 <210> 2291 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2291 ccagggtaga agactagcat 20 <210> 2292 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2292 gaaccctttg gtctaagcaa 20 <210> 2293 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2293 tatagattgg gctttagagg 20 <210> 2294 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2294 atgccctgta gtatgtggat 20 <210> 2295 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2295 gtaatgctgt tgtacactag 20 <210> 2296 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2296 ttttgcataa taggaggtcc 20 <210> 2297 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2297 accaacctta aatagtagga 20 <210> 2298 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2298 tatactccag gttgtggagg 20 <210> 2299 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2299 cattcgatac ctgcttttgt 20 <210> 2300 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2300 cgatccaaac aagcaccctc 20 <210> 2301 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2301 atcgatccaa acaagcaccc 20 <210> 2302 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2302 atcatcgatc caaacaagca 20 <210> 2303 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2303 ccgcacatct ggacctcaga 20 <210> 2304 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2304 ggccgcacat ctggacctca 20 <210> 2305 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2305 gagggccgca catctggacc 20 <210> 2306 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2306 tggagggccg cacatctgga 20 <210> 2307 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2307 attggagggc cgcacatctg 20 <210> 2308 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2308 ctattggagg gccgcacatc 20 <210> 2309 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2309 tcctattgga gggccgcaca 20 <210> 2310 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2310 ttgtcctatt ggagggccgc 20 <210> 2311 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2311 atttgtccta ttggagggcc 20 <210> 2312 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2312 tatgttgtca ctgagggatc 20 <210> 2313 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2313 gtactatgtt gtcactgagg 20 <210> 2314 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2314 gccctcttcg aagagataga 20 <210> 2315 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2315 ctgccctctt cgaagagata 20 <210> 2316 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2316 gtcactaggc acactaaagt 20 <210> 2317 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2317 gggtcactag gcacactaaa 20 <210> 2318 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2318 aagtcttggg tcactaggca 20 <210> 2319 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2319 gcaagtcttg ggtcactagg 20 <210> 2320 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2320 atggcttagc tactcacccc 20 <210> 2321 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2321 ataatggctt agctactcac 20 <210> 2322 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2322 acgacctaaa gacctagcaa 20 <210> 2323 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2323 gatgtacaaa acgacctaaa 20 <210> 2324 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2324 acaagtttcg caataagatt 20 <210> 2325 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2325 gcaagggtct tagtgccaaa 20 <210> 2326 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2326 gtaggactta ctaaatcatc 20 <210> 2327 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2327 gccagtagga cttactaaat 20 <210> 2328 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2328 gtgccagtag gacttactaa 20 <210> 2329 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2329 aggattgcat cacatgtgtc 20 <210> 2330 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2330 agcgcattga gcaaaattcc 20 <210> 2331 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2331 gtagcgcatt gagcaaaatt 20 <210> 2332 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2332 ctgtagcgca ttgagcaaaa 20 <210> 2333 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2333 aactgtagcg cattgagcaa 20 <210> 2334 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2334 gataactgta gcgcattgag 20 <210> 2335 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2335 cacgataact gtagcgcatt 20 <210> 2336 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2336 accacgataa ctgtagcgca 20 <210> 2337 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2337 tagaccacga taactgtagc 20 <210> 2338 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2338 tttagaccac gataactgta 20 <210> 2339 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2339 gtatatttag accacgataa 20 <210> 2340 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2340 tctgtatatt tagaccacga 20 <210> 2341 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2341 gcaaggaccc ttaagtcata 20 <210> 2342 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2342 caattgcaag gacccttaag 20 <210> 2343 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2343 ttatcccaat tgcaaggacc 20 <210> 2344 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2344 agtcaggcac cagattgctc 20 <210> 2345 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2345 aacgaagcca aaggtacttg 20 <210> 2346 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2346 cggccctgac tgtcattcat 20 <210> 2347 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2347 aacggccctg actgtcattc 20 <210> 2348 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2348 ggaacggccc tgactgtcat 20 <210> 2349 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2349 gaaggaacgg ccctgactgt 20 <210> 2350 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2350 ctgaaggaac ggccctgact 20 <210> 2351 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2351 gcctgaagga acggccctga 20 <210> 2352 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2352 tgtggcctga aggaacggcc 20 <210> 2353 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2353 tcatgtggcc tgaaggaacg 20 <210> 2354 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2354 gataatcatg tggcctgaag 20 <210> 2355 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2355 aacgataatc atgtggcctg 20 <210> 2356 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2356 ataacgataa tcatgtggcc 20 <210> 2357 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2357 gtatgctagt cactcattga 20 <210> 2358 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2358 tggcaagtat gctagtcact 20 <210> 2359 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2359 cctggcaagt atgctagtca 20 <210> 2360 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2360 gatcctggca agtatgctag 20 <210> 2361 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2361 tagatcctgg caagtatgct 20 <210> 2362 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2362 tgtagatcct ggcaagtatg 20 <210> 2363 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2363 tcaacattat atcgatgcaa 20 <210> 2364 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2364 cttgtcaaca ttatatcgat 20 <210> 2365 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2365 aacttgtcaa cattatatcg 20 <210> 2366 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2366 gtttcgcaat aagattccat 20 <210> 2367 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2367 ttagctactc acccctgttc 20 <210> 2368 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2368 agataatggc ttagctactc 20 <210> 2369 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2369 aaaacgacct aaagacctag 20 <210> 2370 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2370 aggattcaat agtgtaggtg 20 <210> 2371 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2371 gcacacctgg atttcactac 20 <210> 2372 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2372 ttggcacacc tggatttcac 20 <210> 2373 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2373 ataacttacc ttgttgcaac 20 <210> 2374 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2374 ttgagaagaa aaccctatcg 20 <210> 2375 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2375 atatttagac cacgataact 20 <210> 2376 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2376 ccctcttgta gatcctggca 20 <210> 2377 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2377 aggtcttatt taccattggc 20 <210> 2378 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2378 taatgatcat actggagcca 20 <210> 2379 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2379 ctcacgctgt gtgaatcaaa 20 <210> 2380 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2380 ggaagtctag gtctcacgct 20 <210> 2381 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2381 ctacataggc actctactag 20 <210> 2382 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2382 acccttatgg agacttatat 20 <210> 2383 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2383 gactccacac acctactaga 20 <210> 2384 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2384 caagcaaaga ctacaccgtg 20 <210> 2385 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2385 tatccagggt agaagactag 20 <210> 2386 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2386 ggtgtatatt ccctatccag 20 <210> 2387 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2387 agtgggatgg ctgtcaatgc 20 <210> 2388 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2388 agggatcccc aaatagagcc 20 <210> 2389 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2389 tcacagttgc ttgaccctta 20 <210> 2390 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2390 tatgaaccat ggagtctcta 20 <210> 2391 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2391 tccctaatat agggcagatg 20 <210> 2392 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2392 tataggacct caggagattg 20 <210> 2393 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2393 tcaagaccta taggacctca 20 <210> 2394 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2394 aaagactatc ctggtatgac 20 <210> 2395 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2395 gatttgagcc tgctatgtct 20 <210> 2396 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2396 acattcagct agactagttg 20 <210> 2397 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2397 tgagacccca caatttggtc 20 <210> 2398 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2398 taggtagttc acaactcttc 20 <210> 2399 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2399 atatgccctg tagtatgtgg 20 <210> 2400 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2400 attttattgg tcatctcggg 20 <210> 2401 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2401 tgtcagactt attgaggatg 20 <210> 2402 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2402 actcccacaa ggtactcttg 20 <210> 2403 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2403 aactggtagg atctatggca 20 <210> 2404 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2404 ttcacagagt agtctattgg 20 <210> 2405 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2405 tgtagtatgc attgacaagc 20 <210> 2406 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2406 gagttacaag tgtcatatac 20 <210> 2407 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2407 ggtaggattc atggtccaaa 20 <210> 2408 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2408 cctaggacca gttggttcac 20 <210> 2409 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2409 actgggttga gactattcag 20 <210> 2410 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2410 caatggacca cctaagacct 20 <210> 2411 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2411 ctaatctatg ctgggcccca 20 <210> 2412 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2412 gagattaggc ctaatctatg 20 <210> 2413 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2413 attaggtatg gaggccatgt 20 <210> 2414 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2414 aaggtagccc caatacagat 20 <210> 2415 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2415 gaggtactgt aagccctttg 20 <210> 2416 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2416 gttttgacct aactggcctt 20 <210> 2417 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2417 ctaaggagtg ctctttgtgg 20 <210> 2418 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2418 aggtattaag gcccttggcc 20 <210> 2419 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2419 gtatacaagg tattaaggcc 20 <210> 2420 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2420 taggcagctc tttgtaggcc 20 <210> 2421 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2421 agttctgtat acaccatccc 20 <210> 2422 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2422 ggagtgttag cccaggtgat 20 <210> 2423 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2423 gtcataggag tgttagccca 20 <210> 2424 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2424 ggtgatgaca cccctaccat 20 <210> 2425 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2425 gccttggttg tggtgaaacc 20 <210> 2426 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2426 gtgaactcct gtgactgata 20 <210> 2427 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2427 tatattagtc taaggcagtc 20 <210> 2428 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2428 gtgtaccgag ctcaagaact 20 <210> 2429 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2429 ctgtctctgt gtaccgagct 20 <210> 2430 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2430 ccgcctctgt tattgtgata 20 <210> 2431 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2431 aattgggccg cctctgttat 20 <210> 2432 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2432 agtcaggtac aggtgttgga 20 <210> 2433 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2433 tgtaggttga caggacatgc 20 <210> 2434 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2434 gagggtgctt agtgaactgt 20 <210> 2435 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2435 aagacctgtg agggtgctta 20 <210> 2436 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2436 agtctgtctt tagggtcacc 20 <210> 2437 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2437 tagccattcg atacctgctt 20 <210> 2438 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2438 tgcaggatag ccattcgata 20 <210> 2439 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2439 atgaatgcca ccgtgattgc 20 <210> 2440 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2440 agttgtgtct gagggatatc 20 <210> 2441 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2441 agggtcttag tgccaaatat 20 <210> 2442 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2442 taccaaagtg gctgctcacc 20 <210> 2443 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2443 tagccctttc agcacacttc 20 <210> 2444 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2444 ctggcaatat gtcaacctta 20 <210> 2445 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2445 agtgcacaga taatgactag 20 <210> 2446 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2446 gacttgtctt atggctgcct 20 <210> 2447 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2447 cctaatagca ccagaatagt 20 <210> 2448 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2448 cccaatacag attcagtggc 20 <210> 2449 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2449 tgaagtagtc ctgccctttc 20 <210> 2450 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2450 acactctcgc tgaggacaca 20 <210> 2451 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2451 gggcattcag tgctccctcc 20 <210> 2452 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2452 caagggtctt agtgccaaat 20 <210> 2453 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2453 tatgctagtc actcattgag 20 <210> 2454 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2454 taggtctcac gctgtgtgaa 20 <210> 2455 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2455 gagggaagtc taggtctcac 20 <210> 2456 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2456 taactacata ggcactctac 20 <210> 2457 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2457 agatttgacc cttatggaga 20 <210> 2458 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2458 agtggactcc acacacctac 20 <210> 2459 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2459 tatattccct atccagggta 20 <210> 2460 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2460 gacaggtgta tattccctat 20 <210> 2461 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2461 tgtgcatggt tatctaatgc 20 <210> 2462 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2462 gttgcttgac ccttaattca 20 <210> 2463 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2463 catatcacag ttgcttgacc 20 <210> 2464 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2464 ttgatctatt atgagggcat 20 <210> 2465 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2465 cctcaggaga ttgtacaaca 20 <210> 2466 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2466 ctatcctggt atgactgtca 20 <210> 2467 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2467 atagtgtgga tggtatcctg 20 <210> 2468 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2468 tatagggtgg ttggttcaaa 20 <210> 2469 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2469 accacacata taggctagcc 20 <210> 2470 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2470 gaacattcag ctagactagt 20 <210> 2471 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2471 acttaggtag ttcacaactc 20 <210> 2472 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2472 ccctgtagta tgtggatact 20 <210> 2473 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2473 ttggtcatct cgggtatata 20 <210> 2474 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2474 cttattgagg atggtgtgta 20 <210> 2475 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2475 tccctcttag tgattggtgg 20 <210> 2476 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2476 ctaggcattg aatgagggcc 20 <210> 2477 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2477 agggtaggat tcatggtcca 20 <210> 2478 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2478 ttaatagact gcgattatac 20 <210> 2479 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2479 tccctaagct tagatatacc 20 <210> 2480 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2480 gaccacctaa gacctcaagg 20 <210> 2481 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2481 ttaggcctaa tctatgctgg 20 <210> 2482 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2482 atgagattag gcctaatcta 20 <210> 2483 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2483 agattaggta tggaggccat 20 <210> 2484 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2484 gccccaatac agattcagtg 20 <210> 2485 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2485 ggtgttttga cctaactggc 20 <210> 2486 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2486 ggctaagagt cacctgtatc 20 <210> 2487 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2487 caaggtatta aggcccttgg 20 <210> 2488 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2488 ttgtaggccc aagggaattg 20 <210> 2489 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2489 gctaggcagc tctttgtagg 20 <210> 2490 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2490 tgttagccca ggtgatcagc 20 <210> 2491 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2491 taggagtgtt agcccaggtg 20 <210> 2492 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2492 agggtcatag gagtgttagc 20 <210> 2493 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2493 taaggtgatg acacccctac 20 <210> 2494 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2494 gggtcagttg tgcagttgtt 20 <210> 2495 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2495 aggtatatta gtctaaggca 20 <210> 2496 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2496 ctattatctt cttagggtcg 20 <210> 2497 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2497 ctgtgtaccg agctcaagaa 20 <210> 2498 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2498 catcagctgt tagcagtctg 20 <210> 2499 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2499 aggacactct cgctgaggac 20 <210> 2500 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2500 ggccgcctct gttattgtga 20 <210> 2501 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2501 gaaattgggc cgcctctgtt 20 <210> 2502 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2502 ctagcttcca cctaagagct 20 <210> 2503 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2503 aactctgtag gttgacagga 20 <210> 2504 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2504 tgtgagggtg cttagtgaac 20 <210> 2505 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2505 ctgtcaaaga cctgtgaggg 20 <210> 2506 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2506 ggatagccat tcgatacctg 20 <210> 2507 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2507 ttattcttac cgtctttagg 20 <210> 2508 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2508 agctcatcac aactgggtgg 20 <210> 2509 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2509 agagatatga ttagtactgg 20 <210> 2510 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2510 gtgatattgc agtgggatgg 20 <210> 2511 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2511 acctatagga cctcaggaga 20 <210> 2512 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2512 actgggttac tttccaatag 20 <210> 2513 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2513 caatttactt gatacagggc 20 <210> 2514 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2514 gtcaattgtc agacttattg 20 <210> 2515 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2515 gggcctgtat gtcttgagaa 20 <210> 2516 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2516 agtagtctat tggtgttcct 20 <210> 2517 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2517 atactgtagt atgcattgac 20 <210> 2518 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2518 ttactagggc cagagaatcc 20 <210> 2519 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2519 cagatgacta gcctccaaac 20 <210> 2520 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2520 gcataatagg aggtccttaa 20 <210> 2521 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2521 gtcaaatcaa tttgtgccac 20 <210> 2522 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2522 ctaaggcagt cagggtaatg 20 <210> 2523 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2523 ttaagaagct tgcctttcga 20 <210> 2524 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2524 ttcgatacct gcttttgtga 20 <210> 2525 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2525 ctgatgattt gttgattacc 20 <210> 2526 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2526 atagtgccag taggacttac 20 <210> 2527 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2527 agtatgctag tcactcattg 20 <210> 2528 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2528 ctaggtctca cgctgtgtga 20 <210> 2529 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2529 tatgagggaa gtctaggtct 20 <210> 2530 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2530 aagatttgac ccttatggag 20 <210> 2531 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2531 gagtggactc cacacaccta 20 <210> 2532 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2532 gtatattccc tatccagggt 20 <210> 2533 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2533 tgacaggtgt atattcccta 20 <210> 2534 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2534 agtgatattg cagtgggatg 20 <210> 2535 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2535 catcatcgat ccaaacaagc 20 <210> 2536 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2536 cagttgcttg acccttaatt 20 <210> 2537 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2537 acatggtgag ggtctcaatg 20 <210> 2538 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2538 acttgatcta ttatgagggc 20 <210> 2539 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2539 acctcaggag attgtacaac 20 <210> 2540 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2540 agacctatag gacctcagga 20 <210> 2541 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2541 actatcctgg tatgactgtc 20 <210> 2542 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2542 ttatagtgtg gatggtatcc 20 <210> 2543 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2543 ttatagggtg gttggttcaa 20 <210> 2544 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2544 taccacacat ataggctagc 20 <210> 2545 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2545 cctaaggtga agtctgtgta 20 <210> 2546 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2546 cacttaggta gttcacaact 20 <210> 2547 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2547 tgccctgtag tatgtggata 20 <210> 2548 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2548 tattggtcat ctcgggtata 20 <210> 2549 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2549 tggtaggatc tatggcagtt 20 <210> 2550 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2550 cagagtagtc tattggtgtt 20 <210> 2551 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2551 ctccctctta gtgattggtg 20 <210> 2552 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2552 cctacccttg catgctatgt 20 <210> 2553 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2553 gcctgactag gcattgaatg 20 <210> 2554 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2554 gttactaggg ccagagaatc 20 <210> 2555 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2555 gttaatagac tgcgattata 20 <210> 2556 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2556 ctccctaagc ttagatatac 20 <210> 2557 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2557 attaggccta atctatgctg 20 <210> 2558 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2558 agatgagatt aggcctaatc 20 <210> 2559 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2559 acagattagg tatggaggcc 20 <210> 2560 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2560 tagccccaat acagattcag 20 <210> 2561 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2561 tgcataatag gaggtcctta 20 <210> 2562 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2562 tacttttggt aggtaactac 20 <210> 2563 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2563 aggtgttttg acctaactgg 20 <210> 2564 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2564 tgggctaaga gtcacctgta 20 <210> 2565 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2565 acaaggtatt aaggcccttg 20 <210> 2566 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2566 tttgtaggcc caagggaatt 20 <210> 2567 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2567 gcccgatgac accagccact 20 <210> 2568 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2568 gtgttagccc aggtgatcag 20 <210> 2569 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2569 ataggagtgt tagcccaggt 20 <210> 2570 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2570 gatgacaccc ctaccatggc 20 <210> 2571 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2571 ttaaggtgat gacaccccta 20 <210> 2572 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2572 aagggtcagt tgtgcagttg 20 <210> 2573 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2573 ttagtctaag gcagtcaggg 20 <210> 2574 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2574 taggtatatt agtctaaggc 20 <210> 2575 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2575 cgagctcaag aactgtgact 20 <210> 2576 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2576 tctgtgtacc gagctcaaga 20 <210> 2577 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2577 acatcagctg ttagcagtct 20 <210> 2578 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2578 gaggacactc tcgctgagga 20 <210> 2579 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2579 tgggccgcct ctgttattgt 20 <210> 2580 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2580 tagaaattgg gccgcctctg 20 <210> 2581 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2581 cctagcttcc acctaagagc 20 <210> 2582 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2582 gaactctgta ggttgacagg 20 <210> 2583 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2583 cctgtgaggg tgcttagtga 20 <210> 2584 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2584 acctttggag ctttgactgg 20 <210> 2585 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2585 attcgatacc tgcttttgtg 20 <210> 2586 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2586 aggatagcca ttcgatacct 20 <210> 2587 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2587 aagtgaacta cttggagacc 20 <210> 2588 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2588 tgtatggctt atgcatgcta 20 <210> 2589 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2589 tattaactac ataggcactc 20 <210> 2590 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2590 cagggtagaa gactagcata 20 <210> 2591 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2591 ttagcacttc tataactggg 20 <210> 2592 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2592 atagattggg ctttagaggt 20 <210> 2593 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2593 agacttattg aggatggtgt 20 <210> 2594 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2594 taggacaagt cttatagaga 20 <210> 2595 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2595 atgtgcatac ccagggtagg 20 <210> 2596 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2596 tctatgctgg gccccaattc 20 <210> 2597 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2597 aggttgtgga ggttgttcct 20 <210> 2598 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2598 acctgcagtt atttagccat 20 <210> 2599 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2599 aacctccaag tgcttcaagc 20 <210> 2600 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2600 cttatttgtc ctattggagg 20 <210> 2601 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2601 tcgatccaaa caagcaccct 20 <210> 2602 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2602 tcatcgatcc aaacaagcac 20 <210> 2603 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2603 cgcacatctg gacctcagat 20 <210> 2604 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2604 gccgcacatc tggacctcag 20 <210> 2605 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2605 agggccgcac atctggacct 20 <210> 2606 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2606 ggagggccgc acatctggac 20 <210> 2607 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2607 ttggagggcc gcacatctgg 20 <210> 2608 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2608 tattggaggg ccgcacatct 20 <210> 2609 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2609 cctattggag ggccgcacat 20 <210> 2610 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2610 tgtcctattg gagggccgca 20 <210> 2611 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2611 tttgtcctat tggagggccg 20 <210> 2612 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2612 tactatgttg tcactgaggg 20 <210> 2613 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2613 ggtactatgt tgtcactgag 20 <210> 2614 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2614 tgccctcttc gaagagatag 20 <210> 2615 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2615 ggtcactagg cacactaaag 20 <210> 2616 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2616 tgggtcacta ggcacactaa 20 <210> 2617 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2617 caagtcttgg gtcactaggc 20 <210> 2618 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2618 aagcaagtct tgggtcacta 20 <210> 2619 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2619 cttagctact cacccctgtt 20 <210> 2620 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2620 gataatggct tagctactca 20 <210> 2621 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2621 cgacctaaag acctagcaaa 20 <210> 2622 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2622 aaacgaccta aagacctagc 20 <210> 2623 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2623 gtacaaaacg acctaaagac 20 <210> 2624 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2624 attatgaacc atggagtctc 20 <210> 2625 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2625 tcgcaataag attccattgc 20 <210> 2626 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2626 gtgcaaaaca agtttcgcaa 20 <210> 2627 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2627 ccagtaggac ttactaaatc 20 <210> 2628 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2628 tgccagtagg acttactaaa 20 <210> 2629 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2629 agtgccagta ggacttacta 20 <210> 2630 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2630 gaggattgca tcacatgtgt 20 <210> 2631 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2631 tagcgcattg agcaaaattc 20 <210> 2632 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2632 tgtagcgcat tgagcaaaat 20 <210> 2633 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2633 actgtagcgc attgagcaaa 20 <210> 2634 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2634 ataactgtag cgcattgagc 20 <210> 2635 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2635 cgataactgt agcgcattga 20 <210> 2636 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2636 ccacgataac tgtagcgcat 20 <210> 2637 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2637 agaccacgat aactgtagcg 20 <210> 2638 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2638 ttagaccacg ataactgtag 20 <210> 2639 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2639 atttagacca cgataactgt 20 <210> 2640 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2640 tatatttaga ccacgataac 20 <210> 2641 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2641 ctgtatattt agaccacgat 20 <210> 2642 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2642 aggaccctta agtcataaag 20 <210> 2643 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2643 attgcaagga cccttaagtc 20 <210> 2644 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2644 tatcccaatt gcaaggaccc 20 <210> 2645 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2645 acgaagccaa aggtacttga 20 <210> 2646 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2646 gccctgactg tcattcatat 20 <210> 2647 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2647 acggccctga ctgtcattca 20 <210> 2648 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2648 gaacggccct gactgtcatt 20 <210> 2649 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2649 aaggaacggc cctgactgtc 20 <210> 2650 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2650 tgaaggaacg gccctgactg 20 <210> 2651 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2651 cctgaaggaa cggccctgac 20 <210> 2652 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2652 tggcctgaag gaacggccct 20 <210> 2653 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2653 atgtggcctg aaggaacggc 20 <210> 2654 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2654 ataatcatgt ggcctgaagg 20 <210> 2655 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2655 cgataatcat gtggcctgaa 20 <210> 2656 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2656 taacgataat catgtggcct 20 <210> 2657 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2657 cataacgata atcatgtggc 20 <210> 2658 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2658 ggcaagtatg ctagtcactc 20 <210> 2659 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2659 ctggcaagta tgctagtcac 20 <210> 2660 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2660 atcctggcaa gtatgctagt 20 <210> 2661 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2661 agatcctggc aagtatgcta 20 <210> 2662 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2662 gtagatcctg gcaagtatgc 20 <210> 2663 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2663 ctcttgtaga tcctggcaag 20 <210> 2664 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2664 caacattata tcgatgcaat 20 <210> 2665 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2665 tgtcaacatt atatcgatgc 20 <210> 2666 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2666 acttgtcaac attatatcga 20 <210> 2667 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2667 caagtttcgc aataagattc 20 <210> 2668 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2668 ttagattaaa atctggccgg 20 <210> 2669 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2669 tcactaggca cactaaagtg 20 <210> 2670 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2670 agatgtacaa aacgacctaa 20 <210> 2671 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2671 taaggattca atagtgtagg 20 <210> 2672 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2672 ggcacacctg gatttcacta 20 <210> 2673 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2673 gagcaagggt cttagtgcca 20 <210> 2674 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2674 ttgcatcaca tgtgtcagtc 20 <210> 2675 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2675 tttatcccaa ttgcaaggac 20 <210> 2676 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2676 aataatatta ctgccaaatg 20 <210> 2677 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2677 tgaatcaatt ttcaatattt 20 <210> 2678 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2678 ttataaactt cagcagagtc 20 <210> 2679 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2679 gagttgttat ttgcattaag 20 <210> 2680 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2680 attagcactt ctataactgg 20 <210> 2681 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2681 tcttggtaag gcagctcctg 20 <210> 2682 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2682 tactcatcat gatcttggta 20 <210> 2683 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2683 tagactagtt gaaatcggaa 20 <210> 2684 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2684 aattctaaaa gtcctctctt 20 <210> 2685 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2685 tgtgagataa ttcaggaggt 20 <210> 2686 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2686 attcacttta taaacactga 20 <210> 2687 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2687 cccacaattt ggtcccattg 20 <210> 2688 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2688 gaatagggct ctgcttattt 20 <210> 2689 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2689 ttttatggcc ctcccatcag 20 <210> 2690 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2690 catgaattta attctttaaa 20 <210> 2691 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2691 cattgtggaa ttaaattaac 20 <210> 2692 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2692 tttctaattc aatatcattg 20 <210> 2693 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2693 tcctcttatt tctaattcaa 20 <210> 2694 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2694 caagagatat tcctcttatt 20 <210> 2695 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2695 caataaatag gtcagaaatg 20 <210> 2696 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2696 ctaagtttct taaggtaaaa 20 <210> 2697 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2697 cattttcaaa tattggtatt 20 <210> 2698 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2698 taatgatttg ccctcctaca 20 <210> 2699 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2699 ccttttaaat aatttttcct 20 <210> 2700 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2700 aaaatgttgg catacatttt 20 <210> 2701 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2701 aaaaatgttg gcatacattt 20 <210> 2702 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2702 cctgggtatt gctgtccaaa 20 <210> 2703 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2703 tatgttccta aggaataatg 20 <210> 2704 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2704 ttctttgcat ttatgttcct 20 <210> 2705 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2705 tttctttgca tttatgttcc 20 <210> 2706 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2706 ttactctgac tttccagaag 20 <210> 2707 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2707 ggagtagatt tttggagttt 20 <210> 2708 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2708 tcaactattt ctatcaaggc 20 <210> 2709 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2709 attaatttca actatttcta 20 <210> 2710 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2710 tcttactgat tcagccattt 20 <210> 2711 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2711 tctcagcact agggagaaaa 20 <210> 2712 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2712 aatataaatc ctatagattg 20 <210> 2713 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2713 ctgagtcagt ccaaatgaat 20 <210> 2714 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2714 taccttgaaa ttgagatttc 20 <210> 2715 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2715 tctttttgac caataccttg 20 <210> 2716 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2716 tcaacaattg ccatggattc 20 <210> 2717 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2717 caagacttca ggcagttgtg 20 <210> 2718 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2718 taccaagact tcaggcagtt 20 <210> 2719 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2719 gttaccaaga cttcaggcag 20 <210> 2720 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2720 actgttacca agacttcagg 20 <210> 2721 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2721 cccaactgtt accaagactt 20 <210> 2722 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2722 tatcccaact gttaccaaga 20 <210> 2723 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2723 tttatcccaa ctgttaccaa 20 <210> 2724 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2724 ttgtttatcc caactgttac 20 <210> 2725 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2725 tgatcagctt cttgtttatc 20 <210> 2726 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2726 ccagagcata aaaggaaagc 20 <210> 2727 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2727 tcacaactct tccttagctt 20 <210> 2728 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2728 cagttaggtt agtgcacaga 20 <210> 2729 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2729 ctgctcagtt aggttagtgc 20 <210> 2730 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2730 atactgaagt ctctgctcag 20 <210> 2731 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2731 tgtgccatat ttttctattt 20 <210> 2732 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2732 agaggccctc ttgtttcaat 20 <210> 2733 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2733 aatagaggcc ctcttgtttc 20 <210> 2734 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2734 cgaatagagg ccctcttgtt 20 <210> 2735 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2735 ctgcgaatag aggccctctt 20 <210> 2736 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2736 aaatctgcga atagaggccc 20 <210> 2737 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2737 ctcaaatctg cgaatagagg 20 <210> 2738 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2738 tgctcaaatc tgcgaataga 20 <210> 2739 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2739 gcctgctcaa atctgcgaat 20 <210> 2740 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2740 agttgacata tcttcaagtt 20 <210> 2741 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2741 taatctcagt tgacatatct 20 <210> 2742 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2742 gataatctca gttgacatat 20 <210> 2743 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2743 tgagctatct gtacaaaatg 20 <210> 2744 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2744 gtgagctatc tgtacaaaat 20 <210> 2745 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2745 tttttccatt tttctcttag 20 <210> 2746 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2746 gtttttccat ttttctctta 20 <210> 2747 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2747 tgtgtttttc catttttctc 20 <210> 2748 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2748 gtgtgttttt ccatttttct 20 <210> 2749 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2749 tgtgtgtttt tccatttttc 20 <210> 2750 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2750 tcatctcggg tatataaatt 20 <210> 2751 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2751 tcaccatttt gaccttctta 20 <210> 2752 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2752 ttcaccattt tgaccttctt 20 <210> 2753 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2753 cttcaccatt ttgaccttct 20 <210> 2754 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2754 tgcttcacca ttttgacctt 20 <210> 2755 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2755 ctgcttcacc attttgacct 20 <210> 2756 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2756 actgcttcac cattttgacc 20 <210> 2757 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2757 tcagttaggt tagtgcacag 20 <210> 2758 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2758 ctcagttagg ttagtgcaca 20 <210> 2759 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2759 tgctcagtta ggttagtgca 20 <210> 2760 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2760 tctgctcagt taggttagtg 20 <210> 2761 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2761 gagctatctg tacaaaatgg 20 <210> 2762 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2762 tgtgcatacc cagggtagga 20 <210> 2763 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2763 catacccagg gtaggatt 18 <210> 2764 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2764 gcatacccag ggtaggat 18 <210> 2765 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2765 tgcataccca gggtagga 18 <210> 2766 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2766 gtgcataccc agggtagg 18 <210> 2767 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2767 tgtgcatacc cagggtag 18 <210> 2768 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2768 tcatctcggg tatataaa 18 <210> 2769 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2769 gtcatctcgg gtatataa 18 <210> 2770 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2770 ggtcatctcg ggtatata 18 <210> 2771 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2771 tggtcatctc gggtatat 18 <210> 2772 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2772 ttggtcatct cgggtata 18 <210> 2773 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2773 tcaccatttt gaccttct 18 <210> 2774 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2774 ttcaccattt tgaccttc 18 <210> 2775 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2775 cttcaccatt ttgacctt 18 <210> 2776 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2776 tgcttcacca ttttgacc 18 <210> 2777 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2777 cagttaggtt agtgcaca 18 <210> 2778 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2778 tcagttaggt tagtgcac 18 <210> 2779 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2779 ctcagttagg ttagtgca 18 <210> 2780 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2780 gctcagttag gttagtgc 18 <210> 2781 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2781 tgctcagtta ggttagtg 18 <210> 2782 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2782 gagctatctg tacaaaat 18 <210> 2783 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2783 tgagctatct gtacaaaa 18 <210> 2784 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2784 gtgagctatc tgtacaaa 18 <210> 2785 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2785 cgtgagctat ctgtacaa 18 <210> 2786 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2786 tttcatcagt tagtcaggtt 20 <210> 2787 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2787 cctttctatt tcagaccgaa 20 <210> 2788 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2788 tgcctttcta tttcagaccg 20 <210> 2789 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2789 gtgcctttct atttcagacc 20 <210> 2790 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2790 agtgcctttc tatttcagac 20 <210> 2791 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2791 agtatagatg cctctcctct 20 <210> 2792 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2792 aagtatagat gcctctcctc 20 <210> 2793 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2793 taagtataga tgcctctcct 20 <210> 2794 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2794 attgacacct ccaactgtaa 20 <210> 2795 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2795 gtattgacac ctccaactgt 20 <210> 2796 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2796 tggtattgac acctccaact 20 <210> 2797 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2797 ttggtattga cacctccaac 20 <210> 2798 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2798 tttggtattg acacctccaa 20 <210> 2799 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2799 gttttcgccc gttacctcaa 20 <210> 2800 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2800 agttttcgcc cgttacctca 20 <210> 2801 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2801 cagttttcgc ccgttacctc 20 <210> 2802 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2802 ctccagtttt cgcccgttac 20 <210> 2803 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2803 acactttcat cagttagtca 20 <210> 2804 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2804 tctccagttt tcgcccgtta 20 <210> 2805 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2805 gctataggtg tcacatattc 20 <210> 2806 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2806 ttgtagctat aggtgtcaca 20 <210> 2807 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2807 tttgtagcta taggtgtcac 20 <210> 2808 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2808 gcaatggact tagtacacaa 20 <210> 2809 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2809 ggcaatggac ttagtacaca 20 <210> 2810 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2810 ttaggcaatg gacttagtac 20 <210> 2811 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2811 cttaggcaat ggacttagta 20 <210> 2812 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2812 cagattccta aatacgcaca 20 <210> 2813 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2813 tcagattcct aaatacgcac 20 <210> 2814 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2814 gtcagattcc taaatacgca 20 <210> 2815 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2815 gtggtcagat tcctaaatac 20 <210> 2816 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2816 agtgtcatat gtagcaatta 20 <210> 2817 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2817 ttagtgtcat atgtagcaat 20 <210> 2818 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2818 tatgtagctc agctcaatgt 20 <210> 2819 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2819 cttatgtagc tcagctcaat 20 <210> 2820 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2820 ctgcttatgt agctcagctc 20 <210> 2821 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2821 aaaatccatt tgtccagtct 20 <210> 2822 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2822 tttgcttttc agtcaggtac 20 <210> 2823 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2823 taaaatccat ttgtccagtc 20 <210> 2824 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2824 ctaaaatcca tttgtccagt 20 <210> 2825 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2825 gcattggctt catatttctc 20 <210> 2826 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2826 gagcattggc ttcatatttc 20 <210> 2827 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2827 cattattctc tagtgcctat 20 <210> 2828 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2828 tcattattct ctagtgccta 20 <210> 2829 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2829 gtcttcatta ttctctagtg 20 <210> 2830 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2830 agtcttcatt attctctagt 20 <210> 2831 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2831 aacttcatca atatttcccc 20 <210> 2832 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2832 tgtgggcctc tattaagatc 20 <210> 2833 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2833 catgtgggcc tctattaaga 20 <210> 2834 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2834 tgcatgtggg cctctattaa 20 <210> 2835 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2835 tttatacttt acccaacttc 20 <210> 2836 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2836 ctttatactt tacccaactt 20 <210> 2837 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2837 gctttatact ttacccaact 20 <210> 2838 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2838 caacttcatc aatatttccc 20 <210> 2839 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2839 tggctttata ctttacccaa 20 <210> 2840 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2840 ttggctttat actttaccca 20 <210> 2841 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2841 tttggcttta tactttaccc 20 <210> 2842 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2842 ctttagtatg tcgagaactc 20 <210> 2843 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2843 ccaacttcat caatatttcc 20 <210> 2844 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2844 actcatcatg atcttggtaa 20 <210> 2845 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2845 tcactgagtt tttgtagttc 20 <210> 2846 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2846 tctggaatct tgtagaggat 20 <210> 2847 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2847 ttctggaatc ttgtagagga 20 <210> 2848 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2848 ttcatcagtt agtcaggtta 20 <210> 2849 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2849 attcagcact taggtagttc 20 <210> 2850 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2850 tcccattcag cacttaggta 20 <210> 2851 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2851 ttcccattca gcacttaggt 20 <210> 2852 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2852 gccaggtgtc ttatatctat 20 <210> 2853 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2853 aggtcaacca atttgctatt 20 <210> 2854 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2854 ttaggtcaac caatttgcta 20 <210> 2855 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2855 agccaggtgt cttatatcta 20 <210> 2856 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2856 aacgcaatgt atcaggcaac 20 <210> 2857 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2857 aaacgcaatg tatcaggcaa 20 <210> 2858 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2858 gatcacatta cccatccgtt 20 <210> 2859 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2859 tgatcacatt acccatccgt 20 <210> 2860 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2860 ctgatcacat tacccatccg 20 <210> 2861 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2861 taggtcaacc aatttgctat 20 <210> 2862 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2862 tgctgatcac attacccatc 20 <210> 2863 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2863 ttgctgatca cattacccat 20 <210> 2864 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2864 gccaggtgtc ttatatct 18 <210> 2865 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2865 cgcaatgtat caggcaac 18 <210> 2866 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2866 acgcaatgta tcaggcaa 18 <210> 2867 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2867 gatcacatta cccatccg 18 <210> 2868 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2868 tgatcacatt acccatcc 18 <210> 2869 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2869 gctgatcaca ttacccat 18 <210> 2870 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2870 agccaggtgt cttatatc 18 <210> 2871 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2871 tcaaccaatt tgctattc 18 <210> 2872 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2872 ccattttgac cttcttagcc 20 <210> 2873 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2873 accattttga ccttcttagc 20 <210> 2874 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2874 tctcgggtat ataaattaat 20 <210> 2875 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2875 atctcgggta tataaattaa 20 <210> 2876 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2876 aactgcttca ccattttgac 20 <210> 2877 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2877 taactgcttc accattttga 20 <210> 2878 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2878 ttaactgctt caccattttg 20 <210> 2879 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2879 ttaggttagt gcacagataa 20 <210> 2880 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2880 gttaggttag tgcacagata 20 <210> 2881 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2881 gtctctgctc agttaggtta 20 <210> 2882 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2882 ctatctgtac aaaatggaac 20 <210> 2883 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2883 gctatctgta caaaatggaa 20 <210> 2884 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2884 agctatctgt acaaaatgga 20 <210> 2885 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2885 aggtgtctta tatctatgat 20 <210> 2886 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2886 gaaaccagcc aggtgtctta 20 <210> 2887 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2887 tcaaccaatt tgctattcat 20 <210> 2888 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2888 gtcaaccaat ttgctattca 20 <210> 2889 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2889 caggtgtctt atatctatga 20 <210> 2890 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2890 tttaggtcaa ccaatttgct 20 <210> 2891 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2891 gtttaggtca accaatttgc 20 <210> 2892 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2892 ggtttaggtc aaccaatttg 20 <210> 2893 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2893 gtatcaggca acagaatctc 20 <210> 2894 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2894 tgtatcaggc aacagaatct 20 <210> 2895 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2895 atgtatcagg caacagaatc 20 <210> 2896 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2896 ccaggtgtct tatatctatg 20 <210> 2897 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2897 aaaacgcaat gtatcaggca 20 <210> 2898 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2898 taaaacgcaa tgtatcaggc 20 <210> 2899 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2899 cacattaccc atccgttctt 20 <210> 2900 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2900 tcacattacc catccgttct 20 <210> 2901 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2901 atcacattac ccatccgttc 20 <210> 2902 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2902 tcttgctgat cacattaccc 20 <210> 2903 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2903 ttcttgctga tcacattacc 20 <210> 2904 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2904 cagccaggtg tcttatatct 20 <210> 2905 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2905 aaattattta tacaccatca 20 <210> 2906 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2906 tttatcaata tcttctca 18 <210> 2907 <211> 19 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2907 gcacattctt tctatacct 19 <210> 2908 <211> 17 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2908 ttatagccat tctatct 17 <210> 2909 <211> 17 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2909 ctcaaagatc attctca 17 <210> 2910 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2910 ttacacttaa ttatacttcc 20 <210> 2911 <211> 18 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2911 gtttccatct actattaa 18 <210> 2912 <211> 17 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2912 ctgtatacac catccca 17 <210> 2913 <211> 17 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2913 agttctacta tactttc 17 <210> 2914 <211> 20 <212> DNA <213> Artificial sequence <220> <223> Synthetic oligonucleotide <400> 2914 tatacctttc tttaaccctt 20 <210> 2915 <211> 442080 <212> DNA <213> Homo sapien <400> 2915 cacagcctga gagcctaaga atttggggaa tatgcttcct tcttctagat actggttttt 60 aatgaaagac atagaagagt aattgtcata tagaagttat ttgactctat cattgttgtc 120 tggcccattt ctttagggat tatttgggct aaattctaac ttttctaagc cattttatga 180 ggcctttatt tctaccattt ttcactgtag gcattatggc tcctccacct ggtatgagac 240 cacccatggg cccaccaatt gggcttcccc ctgctcgagg gacgccaata ggcatgccgc 300 ctccgggaat gagaccccct ccaccaggca ttagaggtga gtgggagcat aggggtttga 360 tggttcagcc aggcccctga atatgtgtat cctctttttc tcaatgtttc tatttccttt 420 ccaggtccac ctcccccagg aatgcgtcca ccaagacctt agcatactgt tgatccatct 480 cagtcacttt ttcccctgca atgcgtcttg tgaaattgtg tagagtgttt gtgagctttt 540 tgttccctca ttctgcatta ataatagcta ataataaatg catagagcaa ttaaactgtg 600 aggtactgtt gtatatattt ttttgcctgt tgattttgat gagatcttaa gttactgtgg 660 atgagggtga tgcctattaa gcagttgatt caaatcatat tctctttaat tcttaggata 720 aaaaggtttt ctgctatcta actttcactt tgtgcattga ctggtgttgg ttaataatgt 780 tttcatgacc cgggggttta agtggttgtg ctgcttcaca catggcctcc tgcttctcat 840 gttgctatgt cacattatct gaagggaagt ggggatggga tgaaaggcct tgtaaggcca 900 cctatatact gaaggaagtt gtagtgaatc acagtccatg ctcattacat atcaaggcat 960 ttgaaataga agttactctt tttcttggga tgttgacctc agttgatcag gttttacagt 1020 gtcctatgat cagaatagag gatgtgatac tggaataatc attttctacc attgagtaag 1080 tatttattta taaattacta aatgagtgga agatcctggg tactgggagg caggaggttg 1140 catatttgag ttgataagtt gtactactga taataaagat aactgacaca ctaaaacata 1200 cttggtacac tgaaatacaa attacggtta tgtccagtgg tatcaccaag tgacaaactg 1260 ggagctaaat agttcagaaa tgccctagtc tctaggtcca gtttgaattg gttatggaac 1320 aaagaagcca tttataaaag ggaagagatt tttaggtttt gcagctaagg tttatagtag 1380 gcagcgaggg aatgattcat agtgattgta gcagttggtt taccaagcac taaagagatt 1440 ggtgttaact ccataatact gatagactga ttggaattac attttttctc ttgaatttac 1500 caggagtggt tgtgaatgtc accttttcca tcttttaaat tacatccttg caggtggtaa 1560 tcactcaagg aaaaggaatt atcagagtaa caatagttcc tgttactgac ttgatatggt 1620 ctctgccaga atagcttctc agattaatgg ccactctcag gtaaggaaaa taaagaggcg 1680 aagccttagt tgctttagga gatgatataa tacaggtgtg acatcagtgt tttcagaatt 1740 tgtaaatgtt aaaacaaact tcttgattta ccaaagccac aaccaaagta ctttacctgg 1800 atctttcaag acagagcttc tcagttcaga caaattgact gatgataaga caaacacttt 1860 tcctctacaa accgtggggt agtatgtaga gagacctgtg atttcttccc atactgctct 1920 ggaactactt ctaattatac ttttttcttt gtttgttttt gaaggggaag catttctcct 1980 tgcattggtt tgctggtatg gatggccctt agattttggc atgagtgatt atgcagccta 2040 tttgaagaaa acctgttttc aggacctttt taattaaata tggcctgtta catgagttaa 2100 aggtaagtta taagagctct agattctgca agatgcttgc ttcttgtagt tattttgctt 2160 ggtgataata cattttcttt tgtctggagc ttcctggact ttttgagaat cctgattgtg 2220 atgatataat aggagaaaac ttgggatata gatagtataa ttgagtgtgg tgaatctttt 2280 gttatggaat gctagtctaa gcttctgtgt gtttccacta gggacacaca tcaacatatc 2340 agtcttaaaa cattcttggt agttaatgct tgatgttact taaaaatcat cctacattct 2400 tgcattaaac tacatacacg tggctgggcg cggtggctca tgcctgtaat cccagcactt 2460 tgggaggccg aggcaggcag atcccgaggt cagaagatcg agaccatcct ggctaacacg 2520 gtgaaacctc gtctctacaa aaaattcaaa aaattagccg ggcgtggtgg caggcacctg 2580 tagtcccagc tactcgggag cctgaggcag gagaatggtg tgaacctggt ggagcttgca 2640 gtgagccgag atcgcgccac tgcactccag cctgggcgac agagtaaaac tctgtctcaa 2700 aaaaaaagaa aaaaaaaaaa aaaagaaaat acatacatgt ctcatctaaa acatggttgg 2760 tcaacaactt tctgatttcc tgatacacat tttattaacc ggctccttaa atatatccat 2820 gttgcatatc atgtttgaca tgctttcatt gtagcttata gaataatttc aaatagaatt 2880 ttgggataaa aattatgcta ccttaaaata ggttatgaag tatttgaggt attctctttt 2940 tatatgatag gtaaacttgg cttggaatta aaaagatttt gaaagttgct tagggagctc 3000 cctgcttttg tgaactcatt attccttaat tatgatgtca aatttcagaa gtttgttatt 3060 aacataccgg tattttgctt tttatagatt cttgtaatag aatattacaa gtagaaactg 3120 atttacatag ataattatgt gaaatagtgc tgcttgacta ggattttcat gatctcattt 3180 caaagattag caaaaacacc ctttacctgg tatgtttacc tctgatacta ccttcactga 3240 tttcagcagg tagtcagtta taatccatgg attgaagttt tgatttattt atttatttat 3300 ttgagacaga gtctcactct gttgcgcaag ctggagtaca gtggtgtgat cttggctcac 3360 tttagcctct gccttccggg ctgaagcgat tctcctgcct cagcctcctg agtagctggg 3420 attacaggtg tgggccacca cacctggcta atttttgtat ttttggtaga gacagggttt 3480 caccatgttg gccaggttgg tctcaaactc ctgacctcag gtgatccgcc caactcagcc 3540 tcccgaagtg ctgggattac aggtgtgagc caccgcaccc cgccatgggt tgaagttttt 3600 aaatgcatgt tttccggtag ttaatacatt gcttgattct gtcttataat tgcatttcag 3660 ttctcttcat cttgtccata cacataataa tgcttagtat ataataaagc aaggtatatt 3720 ttcatgggat ttttgtagtg ggagaatgac atctgagcct gaaataggat atttgtgttg 3780 taactttttc agtgtcatac gataccattt tttgaccact tagttgatgc ctctgaaagg 3840 aagagagaat cagatcgcta aaatttgatg tgtcgtcagt gtggatccta ctcagtagtg 3900 tcacaacgag gctgaaaatc atattaagtg cttttaggac agaaacgtaa actgctcagg 3960 taaaataacc ttataaagag aaataagcat atattgcaga ggccttggct aggttcatga 4020 tgacacagga ccttgtctga acataatgat ttcaaaattt gagcttaaaa atgacactct 4080 gaaatccagt cagtgtgcct cactagactt ttcgatttca agattttctg cagaaaatgt 4140 tttgaaaact ttgaatactt aaaaatggca ggtgtagtat tgcactttgc tagttgctca 4200 gatacccttt tttatttgta tagatattct gagttccttt ttttttctac atgttgtacg 4260 ttgtcgaaag ctaaaaggaa acttatcctt ggatcacgga aggcagaggc atttggtgag 4320 atggaaacaa ggatgtgtaa aaatgagacg accacctctc ggattaaaaa aaaaaagtgc 4380 cagagttcta gggttctaag tgatgtccag gaaggaggag gaataatatt tatggagcat 4440 atattatgga acacagtgag tatagtacct gcctttaaat gaatactgtt ggttttttag 4500 gacagttgct tttttttctt ttttcttcag ctgtgtgcag ttgattaact tgtacagagc 4560 ctatcacaca atagatgttt aagaaatatt aagtgaatga atgaggcagc attgctaatt 4620 tttgtatagt gagacagtat ctcacagtcc aggctggagt tcagtggcat taacataact 4680 cactgcagcc ttgaacacct gagctcaaac gatcctttca ccttatcctc cagagtagct 4740 gggactacag tcgcgtgtca acatgcctgg ctaattttag ttttctaatt tttttagagt 4800 tgggatctca ctatgttgct tagactggtc ttgaactcct ggcctcatgc catcctcttg 4860 cctcagctgg tattgtaggt gtgagccact gtgccaggta ctaatttttt ttatgttaga 4920 aaacaagttt ttaggtattt tatagttact tccttatgac aatatctcat cagaatctag 4980 gcctatctga tatctgactc catacgttta taccgtgtag tcagccattc ccagatagag 5040 gtcatttgag ttacttagtg tttaccagca cttgtttact accttgcgat gatatttaca 5100 gtgtattttt gggtatggtt ttggggttat ttggttgttg ttaaaatgcc tgtaatcccg 5160 gcactttggg aggttgaggc gggtggatca cctgaggtca ggagttcgag cccagcctgg 5220 ccaacatggc gaaaccctac ctctactaaa aatacaaaaa ttagcctggc gtggtggcag 5280 gcacctgtaa tcccaactac gcaggaggct aaggcaggag aattgcttga acccgggagg 5340 cggaggttgc agtgagccga gatcgcgcca atggcactcc attcagcttg agtgacagag 5400 gtgagactcc catctcaagg taaaaaaaaa aaatagaaat cagcaactgc tatttgagtt 5460 tacaggagtg agaagtcctc tcttgcatgg tgagatgggg aacatttaat tcaatagaaa 5520 tatttgagac caggtatggt ggctcaagcc tgtaatccca gcactttggg aggctgagtt 5580 gggtggatca cctgacatca ggagtttgag actagcctgg ccaacatagc aataccctgt 5640 ctcaaagata caaaaattac ccaagcttgg tggtgtgtgt ctgtaatccc agctactcag 5700 gaggctgagg caggagaatc acttgaacct gggcggcaaa ggttgcagtg agccgagacc 5760 atgccactgc actccagcct gggtgacaga gtgagactcc gtctggaaaa aaaaagaaaa 5820 aaatgagata taaagttcaa aggatgtatt tattaagcca atataaagta aagaggtggg 5880 gaatgttgta gaagtatatg ttgataaagg gatcaggtgg ttgtacaata agaagggggt 5940 tgcagacatg gagaaacagt tcttctagct cttccacttt cagtatcatc tgtgtgggtc 6000 actggaatcc tttttcacaa tgcctgcttg cccatgagtt ttaagaacta gtacagtgta 6060 gaaatgatta gtaggaaaaa cttggctggg ttaatttgct ttgctgagcc gattcaactt 6120 aaaaagcgag gtccatacta agtgcccaag aatcaagaag gaggctcaca tttgaacttg 6180 atgtttagtt aatgtgaatc attttctgtt gaactaatga gaatacagtg accttgaggg 6240 ttaggttgta catctgaatt gttcgggctg tttcctgtct tttggatgtt ttgtttgtat 6300 agatattttc attttatgtt acatcatttg ttctttggta gcaaaaattg agttgaaatg 6360 atacagttcc tgaaatctat gatttcatgt ttcggagata tgtatcagga ataatagtgt 6420 gggttctcat gagaaaatct ggattgcatt actgtgctac tttggtttct tgtcagagaa 6480 gttagtagtt tagacctcct tcagaatcct ttctttggac tttgtgtttc ttacgttgtg 6540 ccagccttga ttttatttgt ctgtcctctg tctttctata ccatttgttt acacttaact 6600 ctagaatttt ttgatgcatg ttttcagtgt actctagtcc taaaattggt ttacatttaa 6660 ttattgggga gaatagcaag ttgtcgatag tatctgtggt ggcattagtg tatttctgtt 6720 tcagttcttt ggacagtttg ctagtggaaa tagtcattgt atttagctct gtgagacccg 6780 actggcagat tgctgtctct ctctctctct ctctctctct ctgtgtgtgt gtgtgtgtgt 6840 gtgtgtgtgt gtgtgtgtgt atgcgcgccc gcgtttgttt ccttcatgta gattgctgtg 6900 tgtgtctttt tcttcataat tccccttaat tctgtgtgct ttgaatgaca ctgttgttgt 6960 tactgttgtt ttatatccat tgtcacataa aactcttatc atttattctt ccaggccagg 7020 gactgtcctt atgggtagag atacactatc tgcaggaatt tattttttta cgtattttta 7080 ctagttgatg ggaaagacat tgggaaagac ctgggctgga tttgtgatga gctgtgttta 7140 ctgagcatga tgaagtaaag ctcaacgtga ttactctgaa gtccagcctt actgtcagtc 7200 taaggactca ggatacaaat actcaaaaca taaattctta gactctaaat ttcacatggt 7260 ttttcctatc agtacaggtt aaggataatg gcgtgttgta ggtttttcca gtgcaataca 7320 aggaagttgg ttctagatcc tttagtacag ttaatgtttt gtagagtgtg ttctatgttc 7380 actgcattgg tatgtctcat ctttggcatg atcttggctc accgcaacct ccgcctcttg 7440 cattcaagca cttcttgtct cagcctccag agtagctggg attacaagca tgtgccaaca 7500 tgcccggcta atttttgtat gcttttgtgg agacaggctt tgccatgttt gccaggttgg 7560 tctctaagtg atccacccgc ctcagcccca caaagtgctg ggattacatg cgtgagccac 7620 cgtacccagc cacacctttg cttatttcta ctatgcattt caagtgatca tttcaagaga 7680 ataagtactt aggagctcct atgctctttt tttttttaac cctgttgctt gcatcacccg 7740 gttccaaccc tatatgaaag tttcatgagc atgtttctgt cactgaggca gcttctccat 7800 ttggcatata attgagaaat tgctagtttg tggctgagac attggtttga gaggagacgt 7860 aatttatata tttagcagaa tgcttaagtt acatttccag agattaattt aattctactt 7920 ttaattaagt taaccctttg ctgtatcttt acaagacgta ggtggagatt taattttgac 7980 tcttagattc agttaaggtg atgaaattgg cattatatag tttttgatgc tgagccccac 8040 ggagattaaa agatttgcta aacaccatgc aatttttgaa tcacatctct aatctcacat 8100 tattctgtac tctatttttt gcttgtatga ttgatgggtc tttcattatc tgtgattgac 8160 attctatgag taggtgcttt tgctttgcct ataagtcgtt attatgaagg aggaatggtg 8220 aataagaagg taatttagaa aagcctatat taaatatacc atgaacattg aatatagcaa 8280 gatcttattc tctagttgtt atcttagttg ataaattctg tatgtgttat gtgtttgtgt 8340 atacatatgt acatattaat gatgtgggtg ttgatactgt gatcacatga caaatgactg 8400 gtttatagtg aaaagctgtt ggggttcaga gaaatgaaca ttcttctaaa agtgaggtag 8460 ataagttatt ttatagttct tgcctttgag tctctgttct tctggtagaa atgttagtgt 8520 atttataacc tctcagattt gtttggttct cttagtgttc ttgatccagg cagttagcga 8580 tatgttggat gaattgagaa aaatgagttt ttcctttcct actaactgaa ttagattaga 8640 aataagcagt taagtgagaa aaatagggaa ttagtgccag atatgttgag gtgtagtgtt 8700 gacagggggt cttttacctt cagatgtttg gtgcaactta gagaatgcag tggtagttgc 8760 tggcccagcc catccaaaca acctcatttg tggggtgata cttcacagat gacttaaaat 8820 aaatcccctg aaaataagaa tctctggaag agatgacacg tgtatgtgcg tgtgtgcacg 8880 tgtgtgcgtg tgtgcacgtg tgtgtgtgtg tgtgttttgg tggagtggta ggaggagggt 8940 tggcttaatg atgagaatca ttatttcttg aattggatga cactttccat tcctgcaaag 9000 ggagcgtgag gtccagcctt gctaattcat gatcaaagta atttgctgag agtagtggaa 9060 ggaatgagtt agcagaagat ggcaaattgc attaatgagt agtaggagga aaacaaataa 9120 gcaaatttta atgtggttgg aacatgttcc tgagttgtat gaagggagac aggtaaattg 9180 agagtaatgt tatgattgtt tcatttgttg gaaataagga aaacttgcat ggtttgaatt 9240 gtggaacaat aggtggtgta tgttaggagt cagaattatc atttaacatg taagtttctg 9300 ttttacttca gataaagaat gtcagctacc tttcccatgt tagcttctat accttttctt 9360 gaggtgacca taaataggta atattgtctt tcactgagat tgttttaatt agcgaagtgt 9420 gctgattaaa tgtcttttct tgataaatta ttagaatgaa taaaggatgg tatttctaga 9480 tagccttggt tagtcagtga tttgtttaaa tttagtgtgg ataagaatca cctgagggct 9540 ttttaaacac agtttactgg gtcctgacct tagtgtttct ggcttattag gtataagtat 9600 gagaagttga tttttatcaa gtttctagat gctacagatc taggaaccat acttagagtg 9660 ctattatatg tcttttaatg tacactgata tggaaaaagc aatgatacat catgttatcg 9720 catattttaa aatgtgatca tgaccaggga atcttgaaag ttgtcttatg taataatgta 9780 aatcaatgta gaataccata tatttttttc ttgcaaggtt attattaata ggaatgacta 9840 tttgtagcca atgtgttcaa atgcatggga ggacgtaaac acttcataat ttcctggaaa 9900 tacagacata tatcacttaa aataatacat ttctaatata aatttaaatt atctacgtga 9960 tatgaggaaa cgagcttatt tttgataatt ttcctagcag tgaatcaact atactcattt 10020 gaatctaaat taaattaaat ttgagtaaat tcagccattt ctaaattcag tccatataaa 10080 ttcactttgg gtaaaagaag acaaaattcc tgaaaacagt agattaaaaa aataacattt 10140 taagagcagg tatgatctca atgaatatag tgtggtaatt tctgcctaat acctaccctt 10200 ttggaggaag gaaaggtaat cctgtttgtg tttaatgtta attactgaac tctttataac 10260 ttgttttatt tatttattgt ttgattttaa gcatctgctt ctggtggact tacatatgtt 10320 gggtttggga aatttcaaca tacaggttgg cattccagtg gctatagttg tttcttgaaa 10380 tttagtactg ttttccaatg atgattctct ttgggaatag gctgttctct tttacttaaa 10440 aactgtaaaa ttagccactt cagttgagac tcctccaggt ttggaagtgg tgaagaatat 10500 ggatatattc agatcaaatc agtcattctc tgtgatacag caactgaaca agaaacccag 10560 acttcaaaca agcagacttc tttgggttgg actgaataaa atgagaagaa attacagagg 10620 atttgaaaat gtatatggcc taggaattat tgaaattatt ttggagggtg gcaacaaatt 10680 tgggacattg tactttctgt tttaatgtca attgtataat gtgtaactct agtgagcatg 10740 gctggatacc gtggcttcac attttaggta gactgggtgt tttatctact gagtgaatta 10800 cagccttcgg caatgatgtc aaggtagcaa caaaacccaa aaaatccatc ctttagaaat 10860 tgttttaagt cacaatgatg ataccttctt taaaagcttt gacttactga aataatgctt 10920 ttcatttgtc caagatgagt acatagcaga atttggaaat atggttccaa aaggctaaat 10980 agactgactt ttttgatatt tttcccttat agggagaaag aaacattaac ggtttatcag 11040 atgccttgac tgtacttttt actgctttgt cttcaaggcc tagtgtaata attaacatct 11100 agtatgtgtt tgatggatag ccaatttttg cttcattggt atgttgttac cacagtcatt 11160 ggtagagtca atatatgaat gaagaaagta taacaaattt gccctctagt agagtacagg 11220 caaagtatgg ccgtcagttt caccctgatt ttttttcctc cattcttttt tagggtttag 11280 gtcaagaaca agggcatttc attgtaccac atagctgaga gtagggaatt gggacatact 11340 gtcttgcttt aaattaaagt tgtctgtttc atcaagtaga gaggttccta agatattgcc 11400 agatttctga ctcggggttt gttaaaaata gaaaaggtag ttccttaagg ttgtatttta 11460 ttggatgcct ccacctgctt caggctagct cactggagaa taaatattcc aggttaaaaa 11520 aaaaaaagca tgtgttcacg tgaacttgtc ctttgagcaa acctgttgga aatcaagagg 11580 tcattgctgt tggagaggat aagagggtgt acttgttggt gtgttaagag tagttcacaa 11640 cataaaaata aatgtaaatg catctattat atttgggttg gcaaaatata ttggttattt 11700 actctgttga ttcctgtagt gtacataaat atgatctaca actctgtgaa caaaaaggct 11760 tgaaaaattg ttctgaaaat ggacaaatca tgaacagata attgaacaag aaaataagca 11820 gaaagtaaat ttgtgaaata tttcaaactc atttacattc agaaacatct ttttaagatc 11880 actgtgatac attcgactgt caattctgaa gagacgtata aaggaaatgc cagctaagga 11940 gcaaggaaac agctttcatt catgggctaa attgcagctt aaaaaagatg gaccaggatt 12000 atttccttta gaaacttact gtacaaaaga tactgttcac cccattagag aactgatttg 12060 aagttactct tccctgtgag ggctctgtca tcttaactgt attcacatac tttcaactgt 12120 tccccttgct gctaacctca ggttctttag ttcatctatc tggcagagct gatttgggga 12180 aaacaagaca aaccttctca ggttttctta ataaataagc agttgtcatg tttcaagagt 12240 tttagaaatg agcaataatc aaggaagagg acaacgattg catacgttta taatatttag 12300 aacatctttt gccacaataa acactggaaa ccacccactt gtggacacca aacatttgga 12360 tttgtatatt ttgtggcatt ccctcactct aatcctctca tccttaaaaa ttttcagaaa 12420 tttttgcagc aacaaacact gattgcaaca tatgatttag ggtagattta tgaaccattt 12480 tttcactgaa atacatcaac aggagtgagt agtctgagtg accaccccag catggagaaa 12540 actgtagttt acagattctt ctggagcatt tttatttcta gattgcggtg gaagtctaac 12600 cccccttgga gatgtctgcc ttaaagggtc tttggccagg gtcctctgta gagccatagt 12660 ccagatctac tctatttgtg tgctccttac aacatcagaa cagcaactct caatccggat 12720 tcatccccag aatgccgtct gagtcacagc gtggcaggtg cataaagaat tatctactga 12780 attgagaaac atttcaaata tataaaactt gaaatatttt gggtagtctg tacaaactca 12840 agttgacaag ccaaccctgc aggaatatat ggatagaagg ggaaggataa catgttgaat 12900 tcagctacat gcctcatcag ctagaaaacc ttggaagaaa gaaagataga ttgatacttg 12960 cctgaacttc atcaaccaat aatatttttt ttcttgctat ggagagtcca ctcgcctttg 13020 gaagatttac cagtaaaagc cctgcacatg atatacttgt gtgcacatgc aataaggaca 13080 tcattcccca actcctgcta gcattgtgaa agagctccaa atattcaaat aatataaact 13140 ttttttcgtg gacatttagc ttacgagttt gtttaaatat gtgggaaaat tatgtttaga 13200 taatagtatt gaaatgagaa tgtaagatac acattgaatg ataaatgtgt atgaattgtt 13260 cattgtgcct taggtaagcc agacagtgaa attaaatgtg taatagttgt atttttttgc 13320 ataatcttgg aatgtaatta gttaaaagca aacacttaga ttttgaacat gaatctgtta 13380 agcttgttaa tgtagttgct gtggctaaat aactggtttc ctggggaagc ttctatttgc 13440 tagaatttta ttctggaaca gttgttagaa aggaattctc aggtcacctt ttaaagatat 13500 acacaattct gtattcactt tttgagtgca taagggtaat agaaaatgac atgggaagcg 13560 ttaattagaa aaaaaggcat tttgtttatg tgcatttgag gatacagtgt ttgaagtttc 13620 taaataattg ttttatgaca ttttcttggt acatagatat tgctaacaat tagtttgctg 13680 aagtatgtag aaacatttta agaaatgatt ttagaaatat aattgttaaa gtacctctga 13740 tgtatattaa aaatcctttt attttggttt atattgctat ggatgttttt ctgggggaac 13800 ttaatgtata caacttctaa ctaagaagtt ttattaatgc tgctttatgt atgaaagtca 13860 tggatgtgga tgttattttg tcagtggtct ttctgttaaa atttacgtgg tgtaagattt 13920 tcttttcatg atggaattgc caaaaaggcc agcctctaga acacttacat gttaagggtt 13980 gggtgggatt tgtattactt tgtgtatata accgacagga ttgtgttact gaatcttaac 14040 cagcatagag atggctgaca ttttgcattt tgggggacat taaattgtta cacaatgatg 14100 tcattggtta ctgataggag tgtttagact cttagatggc tttgttagta ttaggcaaat 14160 attagatgtg gatttaggag ataagagggt ggggtgttgg agccctgtgt gcacatgagc 14220 atatgttgca gggcctccag acctaaatcc acgtgaagat ggtggtggtg gtcttaccta 14280 tatgttaaca ttacattgta aacaggtaga ctactttcct tttgctagtg ggagtgttaa 14340 atcacctctc agaacattaa ttcattaaat tgcccctaaa cattaattga ttgctggtgg 14400 atatgctaaa tatttttaac atctattttt ctaaatgtat agatgtcatt tttaattcat 14460 aggggataga accagttttg cttgcaaaaa gcaaactgtt cactggatca ttgggcttaa 14520 tttttaggtt gtggtagata taatagaaat gttcttacaa tttgtagtat aatactgtat 14580 atctctataa atatatatgt gactgttttt ctgatagatg caacatggtg gaaatgtcat 14640 cataaatgtc ggtctgcctt tgtttatagt tttcagatgt gtatatgcag ttttttatac 14700 aacagaaaaa ttgccacatg agtcaaatag cataggttag aaaagttctc atttgccaaa 14760 aatatgtgac tttcataata gtgagttgtt tttgatttaa aatgtttcta tctgtagagg 14820 cattttataa gtttttatgg ggatactagc aatgggatgt gaaacctgag ttcattagat 14880 cattgggtga taatggaacc cttatgtgta tacaatatac atggttatat gttttttaaa 14940 gcataggagc tattatgtct gcatggttct aaatatatat acacacacgt aaacacatat 15000 ctatatatct atctatatag atagatagat aaatacatac atatgtagtg aaagcttttg 15060 tttcctccct cacataggca gattatttgt gtgtgtaaat gagcagctga aggggaattt 15120 tgttacatgt gtataagaca gtcacaatat ataattgttt tgctttaatt gtttagtctt 15180 tgatttgtag gaattgccaa cacgtatatt tgtgtgtatg caggtttata tataaataca 15240 tatcactgta taaacaacat ttattgtcat aggatagaaa tattcttaag ttgccagaga 15300 tactgtatgg ctgctaaatg tatagtagaa aaatgttacc ttttgctttt tagcatctgc 15360 atacagatta ctaataggcg tatattgtga ccagtaaacc actagacaag ggcataaaca 15420 ctttagtttg atcagtagaa ttgctatgcc atgtttaaat gggatttatt tggttgatgc 15480 agaatatata attgtatcta gaagataaat attacaaaaa tattttaata tacaatttct 15540 gtcatatttt tggaaatata tttttattca aaagtagaat cattgttgcc aatagagtta 15600 gcatctttgt gtgcttgtga ggtttgattt tgagggtttt cttggttttg ttttgggttc 15660 tggagttcta aaaaatgaga ttgtctttgt ctaaacaatt tttatataaa aatgtacatt 15720 tttgtattat tttttcttat tccaacctaa tcggtggctt gtcccttcct gtgtttattg 15780 ggctgttggg tgcctggata gagctggaga ccatttaact gctgtatgaa taatagataa 15840 gcgtcttgaa taacatctga atttcctagg tatgtagaaa cacccaccat gcacatatat 15900 gaacatacag aatatatgaa tgttaaaata tggtgaaaac aatcttttgc taatagaagt 15960 gttaaccttt atttttaaaa aaaatttggt gtgtatgtag aggtttattt gattgttagt 16020 tgtgtccatg tataatatgt catctacctt tacagatgtg cagaaatttg ttgtatttgg 16080 tggatatatt ttacttaaaa ctatagggca gaagcttttt atgtttgttg aagtgaaatg 16140 gcataccaaa cctgtgtggt agagtgggat ttttagattg ctgtgtgtac agtcaggtta 16200 tatctttaaa atacctattc gttatatatt aatatgtaga cattgctgat acatatgtat 16260 gtaaaaatca gagtattttt attaatatag gcattagctt cttgattcac ttgtttgttg 16320 ggaagcactt ggagaaggat gttgaatact ttgtcatttc atctctgtga cgtacagttg 16380 tcatgtcaac cctcctatct gcgggttttg catctgcaag cacatgcagc tggaaagtac 16440 agcattggca gaatctgaaa cccgagtaaa gagcacctca ttttcataac catgggttct 16500 gaagagctaa gggagttgag gatgcaccga ttttggtatg ggggtacggt acaggtacaa 16560 atccccgatg gatatcacta gacaactgta caatcctctt tagctttttt tttgttttat 16620 agacagtgtg gacgtgcata tattgcaagc atcactttgt taaactatgc ttaaccctgc 16680 aaatgatttt aagagctctg tgtgggtggc tttcttgggt ttactattaa atatctgtgt 16740 ttatcatagt tgttctataa catttcaact ttgtaaatat gtagtttgtt gataaagagg 16800 atagagacat ttttcttttg ttgatagatt gttctttccc ctttgcttag tcttcattgt 16860 gttgctggga ttgtaaaaga caaattactt gcacatattt aagcttatat attaaatgta 16920 tatatgctgt catgttagag agggagagtg gttccctccc ccacattttg atttaaaagt 16980 aaaaattaat ttttattaaa ttgtttgggt cagtttcatg taagaataat ctctacattg 17040 aatggtatat cttggccggg tgcggaggct cacgcctgta atcccagcac tttgggaggc 17100 cgaaggggcc agatcacgag gtcaggagtt cgaaaccagc ctggccaata tggtgaaacc 17160 ccgtctctac taaaaataca aaaactagcc ggccgtggta gtgcacatct gtaatcccag 17220 ctactcggca gtctgaggca gaagaatagc ttgaacccag gaggcagaag ttgcagtgag 17280 ccaagatcgc gccactgcac tccagcctgg gcgacagagt gagactccct ctcaaaaaaa 17340 aaaaggtata tcttattttc tttgatgtac tgaggttcat gatgcaattc attcttaagc 17400 atatactata gaatctttaa attatatggt tctgtgttca tttgtggcat gacagtaacc 17460 aagacaattt agtaaataat cagcaaatga aatatttaat tttgaacatc tagtatttct 17520 agatgtatag agagtctcac gaagtagatt ttttaagtat cttgttgtaa atttgttagt 17580 actgttgtct tttgcaatta atgtggcaat gaaattgatt attgatacac aggctcttgg 17640 agctaaacaa aatttatcgt gttttaattt ggatattaga aggaggaaat gaaaagagac 17700 tctctacatt ttacctgtta ttatatagct taccattata tcagatatga attgcttttt 17760 ttaaaaaact tagattaaat gtcatgtaaa tgcatttagt ctttccagat acacttcttg 17820 atatcataat ttttatttcc tgttaatatt caagatataa atgacttcat taaagagatt 17880 ttctactacc tctaggaact atacaatatt ctgtatgtgt tcccttggtt gcatgacaat 17940 attcaagaca actttgtaaa taatagataa aaaattttaa tttttaacat ctagtctttc 18000 tagatgtata gagtctcaca aagtataatt ttgtaaataa gtcattgtaa aatttcatgg 18060 tttcattgtg ttttgcaaat gtcttggcaa agaacttgat aaaattttgg gcttcttgac 18120 ctatacatat tttggtatct ctttattggg ttgtttagtg taaggaaaaa gttgaaagaa 18180 tgtattttca actttgaatt gtaatcagaa agaaaatata ttttaaccat tgtttagtgc 18240 ttctgttata tattgaaaac ttcagtctta attttttagt tacattgttg atagggcatt 18300 atataaatat acttctatag tcattgtagg aaatgtcttt tataaggaaa tatttcttct 18360 acctctgaat tacacagttt tgtatttact tggactgcat ggcaacattc aaaaaacact 18420 ttgaataaca gataaaaatg acattttcta aagctctagg tttgctagat gcatgaagtc 18480 tcagcaaagt ataaatttgt aaatatttca ttgtaaaata tcataaattg actccttcaa 18540 gtgttcagta gtacaatagg taatcaataa ttggcctctt gggactgact gtaacgtttt 18600 ggtgtttgta tgttttgaga cagagcaata gattgcctcc atatctttta aacattcagg 18660 tctcttgtat aagaaaaata accattgtgg ggtttttgtg catcttatac taatatgaaa 18720 caaacaaaac cccctggata ttttatcctt agaaagatag aggaagacag gagaagggaa 18780 tggtcattgt aaattagata gatatattga gtgttagaag attatttaaa taattgttct 18840 tttgttattt gtactctttg caaatttatt taaatgcata ttcatgtata tcataagtat 18900 atattcacat gcatgtctaa atttagtggc atagatctat ctcaggggta ttaatctttc 18960 attcgtgtac tgatttgtgt tttattttca tttaaaaaat tgtggaacca gtggctgggc 19020 atggtggctc atgcctgtaa tcccagcact ttgggaggct gaggcgggtg gatcacctga 19080 gggtcaggag ttcgagacca gcctggccaa catggtgaac ccccccgtct ctactaaaac 19140 tacaaaaatt agctgggcat ggtggtagat gcctgtaatc ccagctactc gggaggctga 19200 gacaggagaa ttgcttgaac cctggaggtg gaggttgcag tgagccgaga ttgcaccatt 19260 gcactccacc ctaggcaaca agagcaaaac tctgtataaa aaaaaaaatt aaaaaaattg 19320 tggaactagt gttttatttc taagcttgca gatatttcta gaattccact tactgttaca 19380 tctaaatgta tgctgatttt tcgttaaata ataagcaggt ctgtaaacat tttcttttct 19440 aacctctttc catatttata tgagtataga aaaactgtgg ttatgaatat tttttacttt 19500 ttgataactt ttaaaaacta tcagatatgt gataatcaga tagatttcaa gtttacttac 19560 ggtgtaaatt aggaaaattt ttataaagat tctatccagt attgatcaaa agtataaatt 19620 gtgtgtcttt ttaagcagca gtttggcaat gacaatcaaa ttgatactat gtaaaagttt 19680 tgaaatgtta tagctggcta ctggggtttt tatctattcc agttctcgaa aatttaccaa 19740 atataggttg gctgtaaaat cataactatc tgaggtatct gtcaataaat caaagattgc 19800 aatgatgata gcttctttaa catgaatgta attctaacag taaaaaattt ctatatggaa 19860 tatgttttgt agtcctaaat tgatatttta tatcattttt cagtgaacaa gtagttgttt 19920 acaggtgtct gtgcatatgt ctcaagtttt tctaactaaa atattaatag ttaagtctaa 19980 aaatatgaat tatacgtggg gcttgtcatt ctgacattta atacttcagc gtggtgataa 20040 tggtgatata atatactgtt tgaaattgta acacatgagt taaaatcaaa agattgataa 20100 gtacatattt gtatattgct acatgacaaa aatctaggaa gaatatgatt cacatgaaaa 20160 ttctttggaa ggacatgaca gacttttaac agtcctgtat agtgaaagga gaatagaacg 20220 actacttcta ctttctgtat ctgaaatttt caaaagctat ttcaaaatga acatttaaac 20280 aacaggaaat tttagagaca accactttgt gcctgtcttc atccttgaca ttcaacatcc 20340 taggaacaat gggctgttgt attcaacttc ttattcccaa cagccattat gaatggtttt 20400 tgattgatct cacaaagagc atgtgcttta gacattaatg cagcgactac catgaaacag 20460 agtattggat tacctaagga aagaagcaga ggatggaatt tgaggtaggt gtcaaacagt 20520 gaaatttcgt ttgagaaaca gatgagtgaa agaaaatagt aactgaaaca ttcattctat 20580 aaggagagta cattttaata ctggcgatgc tgtatttgtg ggtactgact agatcaagat 20640 gttagaggag gtgtctcttg ggataagttg gaagttatcc ttcattaatt tggtataaac 20700 tgaaaacaga ttgcttcttt ccttttaaag tggttgagtc tctgatgggt ttaaagtagg 20760 cctttgggga tttatagatc attcaaaatt agcaggggaa attttaaata ttctctgcat 20820 ctttctaaaa ggtgtggttt aaagttggtg agaaagtgaa atggttgctg gttgaacttg 20880 attttctcta ttcactatgc ctggctagcc taaaattatc ctaatgggta tgttcaggtg 20940 cctgatttgt atctaaatgt ttctgtattg gatactgttt ttcttaggca atcaggatga 21000 gtgaaaaatt gatttgcagc tgacctgcaa atggaatcat caggaacatc cctttctcat 21060 ggagtccctt aatttacaag ttaactgcaa acataggtaa gaaggttctg gtgctatttg 21120 ggggtgaggt attggtgagg ttttgcctaa gctcaggaaa ataatactgg tacaggtgta 21180 tttcttggcc accttggaat tatcaaatga gttagtcttt aaaatatatt ttatcgaagt 21240 gaaggtatag tttggttccc agaccaaact gagggtcggg ctgctatttc tcgtgcccca 21300 ataatgagat gcagatgaac aggggaggaa gagttagagc tagttacagg aagaaggcct 21360 ggaaattgtc accacaccaa ctcaaaatta caaagttttt cagaacttat ataccttcta 21420 agctatatgt gtacatgtaa gtgtgtatct aaagacataa gtgatctata actaaggtct 21480 gagtcttcga gaccttcctt tggagcctca gtaaatttac attaatttaa atgggtctgg 21540 gtgctgaggt gattaccatt atcttgtttc ctactaaatc atggaggttt ggggagttcc 21600 tttagaaccc ccaataaact tgtttgtgga ggcctggaga gtttcttcag acccctaata 21660 aaacttgttt aatcgtgctt taaggttcaa gagaggccta ggtaaaactt ggtgggcttt 21720 tgtgacattc caacctttgt ataacaaaat ggctctttca gcttttagta tttaacttaa 21780 ccactccgtc aatactgaaa cagttgttat ggaggcctcc attagaggga cctggcctgc 21840 cacaggtgcg cgcgcacaca cagatgagag tacctttaat tagtttactt atctatggtc 21900 aaacacgaca atataactaa taaaagaaat gaccaggcat ctaattacta gaaattataa 21960 aattgacaat atgtgtgttt tcataaatgt acagttttca caaaatgttt tcacatacag 22020 ttctttgata aagggtgaag ttcatggaaa ccacagaaag atgctgatac tgtaaactat 22080 taaagtcatt actgaggttg taagttgact ttgctatagg attgataatg ggaagtgttt 22140 ctaaatgtta acataacctg taataaagtt caacatgagc attcacttaa cctgccgcct 22200 tagctgtttc attagagtgg tatatatctc accttacagt gtttcttctt tttccttgtc 22260 aggagatgat agttccaaga aggaacattt tatcgtcttt gtttttaatc tcaagaatgg 22320 tacctaccat cagtgaatga cctgttgcag tgctttcatt gaagtgttct tcgttccctc 22380 agcaatatga ttgtaagggc agttgagtgc taacttgact gggagagggg cggtttggtt 22440 agacaggact tgatatattc tgtttttcat aagcttgatg tttttttctg gcagctactt 22500 gacattcaga tctgattggt tacatattgc tatgtaataa attatcctga aacaggggca 22560 taaacaatat tgttatgtcc atggattctg ttggtctgac catgcccagg acagtttagg 22620 aattgtatcc tctccaaagt ttcattgtag cttctgtgtt tttagtatag ttactatttc 22680 tttctcatca aatagactga actccttttg ttattatcat ttaaatattt aggcattgtt 22740 gtcatgtata ttgtgcataa atgcatgtat actgcaggta ataattctgt atgtgaacaa 22800 gtgacctaga ggtaaaggaa tccaaataca gagacgtgtg gataatgtgg gagaggtcag 22860 tttttcacaa gacataggaa agaggctggg cgcggtggct cctgcctgta atcccagcac 22920 gaggccgagg tgggtgtgtc ggtcacttga ggtcaagagt tcaagaacag cctgaccaac 22980 atggtgaaac cccgtctcta ctaagaatac aaaattagct gggtgtggta gtgtaatccc 23040 agctacttgg gaggctgagg caggagaatc gcttgaaccc gggaggtgaa gattgcagtg 23100 agccaagatc acaccattgc actccagcct gggcaacaag agtgaaactc catctcaaga 23160 aaaacaaaca acaacaacaa caaaaaagaa ggaaagagct aacatctgac ctcctttatt 23220 attagaatac tccaaaagga attttgatcc acatgctctt tcttcataat agaatgaatg 23280 ttgcatgtca ttttacagac aaattttatt agttcttgct gatgatataa actttgcttc 23340 taaccttttc ccattttccc aactgtgtct ctcaggtgat gactgaaaaa gggaaactgt 23400 gccactattt gtaccatcat tttcaccaaa atctaaaaat gctttttatg acgtatggag 23460 acattcttca tgtttgtttc agtggacact ccttgcagat gtaaaaaact gagaaaactc 23520 acttttggaa agtgacctaa agagtgtcat tgaagtgaat tttaagtagg cacgatgatt 23580 gttttcatgg ttgctgttgg atcatatctc aggagctgga atgacagaca ttattgaaca 23640 aagaaatcag gatagtggaa cttaaagggc ttcatctcag tgctttcata agtatgaagt 23700 gcatatattt ataattttca ctaatcacag ggtaaatata aaattgattc attaaaaatg 23760 tttcataaga attcaaagga catagaattt tgtgaaatgt agtattttta cttaagtgcc 23820 ttttctctgc ttctacccca cagccaattt tttataaacc agttgataac ataagtagtt 23880 tttgggggat gatacattac ttatacattt tctatgtagt aaacatgtat gtgtatgtgt 23940 gtgggtgtgt gtctaattac tttgttggac agattcctgt ggtttggaac tgctggggcc 24000 aagtttatac aaaaatctac atttttgagt aaactcccca tgactctagt aagtttccac 24060 agtatttgag tattctttat ttcctaaagc tgtacaaaca tcagataatc aatatttgta 24120 aggatcgata atataattta taatgaaatt gctttatcag ctattaatgt taactacatc 24180 atcttcatat agccttataa ctcatttgtg ctattccatt ttcctctgtt ccttttattt 24240 tcacttccct tgtaatgtta gtctctttgt actgatttct gaagagttca tttatgatta 24300 aacatgttaa cattttgtct agaattgcaa atatgttttt tctcattcat tttactatgg 24360 tgttttattt tttggttata cagaagttgt atattgaaat ataatcttgt tctgttttat 24420 gactttggag ttttgtggtt ttttaaaaca tgtttacatt ggtatcattt atttgtattg 24480 ccttctattt cagcagttag tttgtcattt ctttttccat taatcatcat tctggtgtta 24540 atgaatgcat taaatattta aagtactcac tttgacccgt gtagttatct gttaagttct 24600 accataaaga aaatttccag gtaaaattgg ctacatttct gttaacttgc cttaccattt 24660 tattgacact ttaataatta ctaatgattt atactgtctt atctattcca ttgagttcta 24720 tctcatttct cttctttttc agaatattcc ctctgtatac ttgcattttt ttctatcaat 24780 tgacgcttac aattattttt gcaagttgga aaaaaatgca gtattaattt catttgcaac 24840 aaatttaata gattaattag gagagaatag atatctttaa aattgagtct tctgtccaac 24900 tgcaaggtag gtctttctat ttttaatgga ataataattt ggggatattg ctagtgcagt 24960 tttttaaagt attttttaat actaggcatt ttttagttat ttgttaattt agtgatttgg 25020 attagtcatt caacttgtct aattggtatg tgaaaacttt ttgtatgtct tttctagtaa 25080 tctttactga atttctaaaa ttatgacttt cttgaacaat ctgtcatttt aattaccttg 25140 attaaagtac atttgtaagt acttctagga tatatggaag tagaaagtat acttggcaat 25200 tggactgtta attgcaatcc ccttaggtca tggttgtttt tgttcttatt ggtattttag 25260 taatctttta gaagaaagat gttttaccaa atttggtgac aggtttaata aaatttcttt 25320 ttgtatagtt gaaaaacttg tccttataat tattaaggtt aaaattaaca tattccaaaa 25380 ttgaacatta ttccatccca tgaatgaagt aaattatatt ttagtatata ctccttaatt 25440 atagttgtta taatttcatt tggaatttct gaaatgattc ctaaacaaac agctttatac 25500 ttgttctgtt atcagaggtt tttaatgttt tactggctct ttgaaaccat tttgagtatt 25560 tctgacacag actagaaaca agtaatattt ttctttaatt attttgaaat gttggcttaa 25620 aaaggtgttg aaataatagc gtgttttttt ttttaaagtt atttatcttt tgtccaaaat 25680 caactaagca tttatgcaag catgtgtttt ttggaaccct tttttctgtt tccttgttct 25740 ttgtgttttt ctttatgcca atatcacact gttttgataa ttgtagcttt gtagttaaca 25800 ttttgaaatt gagaactgtg actcttccac ctttgttctt tttcaggttt attttgctca 25860 tttcagtcct ttgaaactct gtatgagttt taggattttt tttttaattt ttgcaaaaaa 25920 tgtcatggga agtttactag ggattgagtc tgcacattgc atgagtatta ttgacataaa 25980 caatactaac tcttccagtc catgaacatg ggatgtcttt ttatttatgt catttatttc 26040 tttcagaaat ggtttgtaaa tttcattgta caaaaaattt tctttgatct tactggttaa 26100 gttactttct aagtattgta tttttaaaat gctattgcaa gtggaattgt tctttgaact 26160 tcttttgtga attgttcatt gctatttttg catgctgaat ttgtagcctg gtattttgtg 26220 gaatttatca gttctgagat ttttttttat gctcccaagg aaaattttag cccgtaataa 26280 tttttttgga gacatagtct cactgttgcc caggctggag tgcaatggca ctatctccca 26340 ggtttgaaca attctcctgc ctcagcctcc tgagtaggtg ggattacacg tgtctgccac 26400 cacgcctggc taatttttgt gtttttagta gagatggggt ttcatcgtgt tggccaggct 26460 ggtctcgaac tcctgagctc aagtgatcct cctcccttgg cctccaaaag tgctgcaatt 26520 acaggtgtga gtcactgtgc ccgaccagcc tataaaattt tagtggatgc caagagagat 26580 acttctactt cttttctgac ttgggtgtca tttctttctt tttgttactt gattgctgtg 26640 gcaaggattt gtaatactgt gttgaaaaga agtggcgaaa gcaggcatcc ttgcttttgt 26700 aactgatact agaggaaatc cttttagtgt ttaacctttg agaataatgt ttgttttgag 26760 tttttcattt atagctttta ctatggtgat gtgatttcat ctattcctaa tttgatgaat 26820 gttgaatttt ttattcctta gtctttgtct tgctttggta agagggtaat gctggcccca 26880 taaaatgtgt tggggagtgt ttcctccttg aatttcttag aaaagtttga aaacacttgt 26940 tatttgttat ataagtattt atttgatgga agattttttt tttttttttt tttgagactg 27000 agtcacgctc tgtcgcccca ggctggagtg cagtggcgcg atctctgctc actgcaagct 27060 ccacctcccg ggttcacgcc attctcctgc ctcagcctcc caagtagctg ggactacagg 27120 tgcccgccac cacacccggc taattttgtg tatattaagt agagatgggg tttcaccatg 27180 ttaggcagga tggtctcgat ctcctgacct tgtgattcgc ccgcctcagc ctcccagagt 27240 gctgggttta caggtgtgag ccactgcgcc tgaccggaag atttttcatt aataattcag 27300 tactgttaat agtttcatgc gtgtggtttt gttttggtgg cctttagttt cctaggtttg 27360 taggaatttg tacatttcat ctagattatc taatttttta acattcactt gcttatagta 27420 ctcttacaat ctcttagttc tgtagacttt atgtttctga tggtagcaat ttgagtctgc 27480 cctctttttt tctagtccac ttagctgaag ctttgtcagt tttcttgatt tttgtttatg 27540 aagaaccaag tggttatttt gtgttcattt tctgttttat tcatctctat atcattcttt 27600 atgtccttcc ttttcctctt tgtgtttact ttgcttgtgt aattctttaa tttgtacagt 27660 tggttgattt gaaatttttt ttcatgttac attaataggt gtaagattca taagaaaaca 27720 tgttttattt tcattttcat tcattcccac atattttcta attttcctta taacctcttg 27780 gtgtactagt tgtttgtgtt ttctcatgtc cacaaatgtg tgacttttcc aaggctttcc 27840 ttctgttact gatttctaaa ttcattgtct tgctgtggtc agagaagagg cttctttttc 27900 tgtctgtttt ttcaaaattt attgagactg aatttgtgaa ttaactacat ttgttgtgaa 27960 aaatatctca tgcacttgaa ggggagtgtg cattttgttg ttcagagatt gttgtgtgca 28020 tatctgttag atataattga tttattgtga tattacacac ttctattttc tctttttttg 28080 tggggtgagg ggtgagacag agtctggctc tatcccccag gctggagtgc agtggtgtga 28140 tctcggctca ctgcaacctc tgcctcccag attcaggcga gtctcctgcc tcagcctccc 28200 aagtggctgg gattacaggt gcctgccacc acacctggtt aatttttgta tttttggtag 28260 agacagggtt ttgccatgtt ggccagggtg gtctcaaact cctgaccttg tgatccacct 28320 gcctcggcct cccaaagtgc tgggattaca ggcgtgagcc accacacctg gcccacacct 28380 ctattttctt gttttctggt tattctaccc atcattgaga gtaggttctt gaagtctata 28440 tttcttagtg aggaaatgtc tatttctccc ttcttttatg tcaatttttg tttcatatat 28500 tttgatggtt tactaggatc ataaatgttg gtcatcttta tcttgtaatt tttattaatg 28560 tataatgtac atttttgttt gttgtaacat tttggattaa aagtctgttt tgtctgactt 28620 aagcagtcta caaaataact gcttctgtaa caccttctct cctacccctt tcagttgatg 28680 ctacaaaatt atatgtttaa cattgtgtat caaaatatat atatatattt gagatggagt 28740 cttgctctgt cacccaggct ggagtgcagt ggcgtgatct gggctcactg caagatccgc 28800 ctccagggtt catgccattc tccttcctta gcctcccgag tagctgggac tacaggtgct 28860 cgccaccacg cctggctaat ttttttgtat ttttagtaga gacggggttt caccatgtta 28920 gccaggatga tcttgatctc ctgaccttgt gatccgcccg cctcggcctc ccaaagtgct 28980 gggattacag gcttgagcca ccacacccgg cccaaaatat attttgtaaa atttattttt 29040 tgttaaattt tttagaagat aacttgtaga gttataatca aagttacaat aatatttact 29100 ggttttttgc ctaatgtgtg gttttataat tgatcaattc aagtcatgta gaatctaaaa 29160 aaggcaacag gctgggcata gtagctcatg cctgtaatac ccagcacttt gggaggctaa 29220 ggaaggagga ttgcttgaga ccaggagttt gagaccagcc tgtgcaacat agcaagaggc 29280 tgtctctaca aaacaaattt taacaacaaa aaatagctgg gtatggtggc atattcctgt 29340 agtcccagat actcaggaag ctgagatgca agggtctctt gatccctgaa ggttgaggct 29400 acggtgagcc atgatgatgc cactgcattt tagcctgtgc aacagaatca gagcctgttt 29460 cataatgaaa aacaagtgga gggacagtac accattatta acctctcata attgctcaat 29520 tatttacctt taaccacatc tttatttctt tatagggctt ccatttacta tttatttcaa 29580 ccttcaggag tcttttcagt gtttctgttt ggtgggggag cagatctaat gtaaacaaac 29640 tcctgttgtt tgtacatctg ggaacgtatc aatttctccc ttacttttta attaacagtt 29700 ttgttggata ttagattctt agttgagtat tttttttttt ttagcacatt gaatgtgtca 29760 gtccactacc ttctggcctt atgagaaatt gactgataat ccctgttaca tgatatcgtt 29820 tttctattgt tgctttcaga attctttctc ttttgctctt catagttgaa agatattgtg 29880 tctcattgtg ggtctttgag ttcatcttgc ttggagtttg ttgaggttct tagatgttag 29940 aattcatgtc tttcatcaaa tttgagaagt ttccatctag aatttcttca gatattcttt 30000 ctattgcatg ctttctcttt tctgggaatc ctgcatcgtt tgtattggtt agcttgggtg 30060 gtggaccaga agctgtttag actcttacct ttcttcaata ttttttcttt ttgttcctca 30120 gaattgataa aattctgaag tttgctgatc ttttttgttg cctgctgaga taatgcattt 30180 gaatccctgt agaaaatttt tcatttcagt taattgaatg tttcatgttc cagaatttca 30240 tttggggttc ctttttgaaa gtttttttat ttttgattat tgatccttcc attttgctca 30300 tgcatcattt tcttaacctt ctctatcact tcctttagtt ctttgagcaa ctttaagaca 30360 gttgttttaa aagctgctta cctgtcttac catctttgag atcagaagtg gtaaactgat 30420 gagagcacag cctctcaatg tttgtataac agagtggtgt gttttgtttt ttgtttatgc 30480 ctaccatcac tccttctgca agctgtatgt aagttgtcca agaaatgtgt acagctacct 30540 tgcgtgaggg tgtaggagtt agggataggt aatttgtact ttgctaagag ttgatgttga 30600 gtgaaattaa cctcaataaa tctgaattta gggttaatac aatcctccag agttccaaac 30660 cagttatatc ataccgatta ttctggtgta tttatcatct cagggggaga aagagttctg 30720 ttgcgtcctg ctctgccata ctcccagaat cctcagctca ccagtttttt agtttgtttg 30780 ttttgttttt gtatggatac agtttctcat tctgtctccc aggctgtagt gcagtggcac 30840 tatcatagct cactgcagcc tcgacttgtt gggcccaagg gaccctcttg cctcagcctt 30900 ctgagtagct gggactatgg acatgcccga ataatgtttc ttttttaaag agatggggtc 30960 ttactacatt gcatagcctc atctcggagt tctgcactca agcattcccc cagtctcagc 31020 ctcacaacgt cctgggattc taggcgtgag tcactgtgcc cagcttgttt tacagtagtg 31080 aaatgaatct gcccatttat actttctgat tatcaatgaa agttgtgttc tataattttg 31140 ttgcttttca gttgtgatag tttatgcatc acataaaatt tgccatatta accagattta 31200 attgtactac tcattagcat taaatgcact cacagtgttg tgtaactaac accatattca 31260 aaacttttgt catcttaatt ggaaactcta tacctgttac tctaatccct agtcccttgt 31320 ctccccaatc atgttttctg catttgattt tgcctattgt aggtatttct tacaagttga 31380 atcacatagc atgtgttttt tggttcctgg cctattttac ctaatgcttt caagtttcat 31440 gtaatacatg agaacttcat ttcttattat gaccgagtaa atccattttg tgtatgtata 31500 catgtgtgta tacatgagtg tgtgtgtata cacatataac acaattttta tccatctgct 31560 aatggataga attttaaatc tattcctctg ctaatggaca ttttatatgc cagtgctcac 31620 caaaacattc acagtgtcca ttaagagatg aatacattta aaaatatgtc cattaatatt 31680 tgagtgagca ttggcataca aatatctgag ttcatgtctt cgtatctgat tatgtatata 31740 ggggaatgaa attgctgagt tatgtggtaa tttaatgaac tcactttttg aggaaatatt 31800 tgttatttat tatgagaaat tgaagtcacc aaaaatgaga actgaataat gaaccttctc 31860 atatctagca actagagtta ataactatga acattttgcc atattttgaa aattacagtt 31920 accatggtga tttaatcctg aataggttta tatttttatg tatcaatttt taaaataatc 31980 acaatatcct atctctacct agtaaaattt actaaaatcc cttatgtgtc ttctaaacac 32040 acaaagaaaa aacaattctc atttaaattt ctcaaggttg tgcatggtgt ctcaagcctg 32100 caatcatagc atttttggag gccaaggcat tttgcttgag cccaggagtt ccagatgagc 32160 gtaggcaaat agtgaaacct gttttcacag gaaaaaaaaa aaatgaggta tggtggcatg 32220 cacttgtgaa cccaattatt tcagaagctg aagcaggagg atcacttaag cagtaggcta 32280 caatcacaac actgaactcc aggctgggta acagagtgaa acattggctc aaaaatataa 32340 aaaattctca gttgtgcgaa tgatacaaca gttttttgag caaatctgga tccaagtgag 32400 taattcactt ttatctaggc tatttttatg ttagtcttga ctgtattaat ttatattcaa 32460 tcttaaatct ctcttaatta aggtatgaaa gtcaaccctt ttttggttct atatttaagt 32520 aatttttaaa aaaatcttga attaaaaaca ttatttagaa gtaactttca tattctactg 32580 gatttcttat ttgctggttt ttttgggggg attgattcta ccctttattt ttagtattct 32640 gaatgagttt tggtgagcta ctgtggtcca aaatatatat tgtgtataca caatacatag 32700 tctgaattct tgtataacaa aagtacagtc catatttgta aggggtgctt ggaaaggtat 32760 attaggtata ttaccttaca tgtgtagatc ttcataagta atagttggca aggtctgcta 32820 taaacttgtt acatatttct atatttgtca ttatattaga gacattttta gtctttgatg 32880 ttatttttcc cattaatatg gtgtcctgac ctggtcatgc tttcagtttt tcatgagatc 32940 atgctaatga aatttcttaa aagttttgca aatataatct gataacgtac tttgattttt 33000 tgaaaaaaag tcatctctta cccagtaaat atcaactaat tgctggtttt cttttgtgat 33060 ttcttctcaa tgtattttat attaaggttt ggagatacca gtccttttaa gcctaatcct 33120 catgctatct ggtaaaaatt attaacaact aaaaattact taatgtatat tacaaaggag 33180 gtagtaccat ctatgaaatc tttttgataa atcttactcc actctgtctt atgtatgttt 33240 aaatgagcac cagaagaatt atgcattaca tttcatttga ttggttaatc tttgagctct 33300 tggtttttaa tatttgtttc ttgctgtttt ctctttgagg aaatgagtta tttgcgatat 33360 aaaactttca catttctaca ttgtgcccat agtaggatgc cacccctgtg gtcatgttta 33420 atagtttttt ctcagtgttt cggtgtttaa tattttctat cattttttta aaaaaatatt 33480 caacattgag acatttttct caatgtatta tattctcaag atctgatttt ttgtctgact 33540 agttttatca aatcattaat tcagccattt attatatgaa caccttttgt aaaacagaag 33600 aacactaatt tatcatgata ttttcatata tattttgtga tattgagaat cattaagtat 33660 tttatcacct gctttttaca aaaacacaat agtctctcat ttcactaata gttatacatt 33720 tgctctaagt atcagtaaat ttactctgaa tgataagttc ttcatttaaa taggaactta 33780 atcaactttt ttgggatttc agttcaaaag gaaaggtaaa taaatgtttt ttcccttatc 33840 ttaccattta tataataatg aattgatgtg caagtaatct tcaaaggtga ctagttttta 33900 aattcatgtt ctttattcag aagacagaaa gcattttcag gagatttgaa tatttgaagt 33960 tatattttaa aggtgataat gctaatagca taattaaaaa acagtttctg catgtaaaca 34020 catggtagaa tataacaggt aatatatatt tgtaattatt tttctatttc atgtttattc 34080 aaatgtatgt acaatctctg tagcttgtag tttggctgtg ttatgcttta taaaatttat 34140 ttatctgaga cagggtctca ctctgtcgcc caggctggag tgcagaggca tgatgtcagc 34200 tcacagcctc cacctcccag gttcaagtga ttctcctgcc tcagcctccc aagtagctgg 34260 gactacaggc gtgcaccacc acatctgact aatgtctatg tatatatttt ttagtagggt 34320 caggttttca ccatgttggc caggctggtc ttgaactact gagctcaagt gattaacctg 34380 ccttggcctc tcatactact ggaattatag gcatgagcct ccacacccgg acataacatt 34440 tattttttat tttatatttt atattttata ttttatttta tttttgagat ggagttttgc 34500 tcttgttgca caggctggag tgcaatggca cgatctcgca tcaccacaac ctccagctcc 34560 cggttgcaag cgattctcct gcccagcctc ccaagcagct gggattacag ataagtgcca 34620 ccacgcccgg ctaatttttt tatttttagt agagtcagag tttcgtatgt tggtcaggct 34680 agtctcaaac tcctgacctc aggtgatttg cccgcctcag cctcccaaag tgttaggatt 34740 acaggcatga gctaccacgc ccggcccata aaatttattt ttatcccagt tgtgtgtact 34800 tatttactta tgtatttatt tatatttatt tatttgagat ggagtctgac tctcttcccc 34860 agactggaat gcagtggcac aatcttggct cactgtagcc tctgacacca gggttcaagc 34920 catcatccca cctcagcctc ccaagtagct gggattttaa gcatgtacca ccatgcccag 34980 ctaattttta tattcttagt agagacaggg tttcaccatg ttggccaggc tggtcttgaa 35040 ctcctgacct caggtgatcc acctgcctcg gcttcccaaa gtgctagaat tagagaggtg 35100 tgagcctcca taaggaatat gatttgaagg gaagagggga tatgagtgtg aggtaaatgt 35160 tttcctattt aaatattgaa atataaaagg ctattcagtt tccattcaag taacatttgg 35220 aagcttttta tttcataata ctattttgtg tagaaaccat tactgtttgt tttgtatttg 35280 tgtaggtaaa aagtattatg aaattatgta attacagtat tcactctgcc aaaaaaaaca 35340 aaaataatta taactcgggt atctaatgat tgaacattta gtaattcttc cctgacaaaa 35400 agagaaaaat attataactc aggtatctaa tgattgaaca tttagtaatt cttccctgat 35460 tataaaagta gcacatttat actttggaaa ataaaacagc atgtatggga aaaagtaata 35520 aacatagaga aattccatca cctcccttcc cctctcctcc aagaaaaagt ggcttacgcc 35580 tgtaatccaa gttcttaggg agccagaggc aggaggatag cttgagccca ggagtttggg 35640 acttgcctgg gcaatatagc gagaccctgt ttccccaccc caccccccca aaaaaagaaa 35700 aacgtaattc catattttac aggtttagtg ttgacttcat aaaagatgga agggaaggtt 35760 atcagagtat cccattgtag tgattatagt gctcagattc tagctccata cctgttagaa 35820 cacattcgca attgtcagct taaactatat ttgtatgtat tgtttgtctg ttttgtatta 35880 aaggcaaaag ctcattatca attagttgta tgttttaaag agttggccac aacatccatc 35940 ataagaccta tctaaagagg aatacatgat gtcttagtac aaaggagtag agatacaatg 36000 aatgtattta ttttcatgtt tcttaagagg gaatgcacta gcaattgacg gtaaaataga 36060 tacaaatcaa gtaaagaaac cagtatattt ttagtcatta tgtcgctttg aacaacaatt 36120 tgtttaatca ttttgcggta actggttgct tggaactgcc ttattttttg tattcaatat 36180 atttatttat gggagtgtat acatattcca gggtgttcta gttcctcagg gaaaatctgg 36240 atgacataga agaattttgt tctttattat gagtcaattt ataatttcat ctttttttaa 36300 aaggcatttt tcctacagct agacgttttg attgtcactt ttgttgtgag aaaaaaatta 36360 caaagacgtt gtaaagattg ggaatgagga aggtgacttg atcgggtatc acagacttac 36420 aaaatcttgt atgtaattag agttatgtta atggcacatt tataagcaaa gtaatgtcat 36480 ggaatggaag acccataagt tgacatgaga aacagaaagt gtattaaagt taatctgcat 36540 tcatgggggc agattgttag ccaaatgaat aaagaattag attcatcttc atggtatgta 36600 gcatgaagaa tttaaaatga atcagaggtt taaattaact gcagaaatta tagagtttca 36660 gaaaacgaat ttctctccaa ttttgaggaa attactgatg atacacattg tagaagcaac 36720 aagaaacaca aagattgata gtaaaaatga aattacagag ttgaaaaagt tgtgacatca 36780 cataagaaga gtgaaaccct tggtgtgtaa gatataatcg gggaaaaata ccagttcaaa 36840 ggaaaagtga cttgagcaca tagttcactg aaaaaaatac acaaagtgct gttaatcata 36900 taaaaggatt cttgggtttg ctcataataa ggataatgac aattgaaaat acaactaaga 36960 tataattagt ttctctacta ttagactagc aaaagtccag aagtttgaca acattttttt 37020 ttttttggca acatgttcgg aattatggaa aatcatacgt tgcttctggg catgtaaaat 37080 gtaaaccata tgggtaggaa tttaatattt tgtaaattta tatctgtggc aaatacatag 37140 ttcatctcct agtaatatgt agcagtaaga aggattgatg gatgtttgta taccactatg 37200 tgataatgtc ttggatataa tgtagaaata ggggagaagt cggctacagg aagtaaaaat 37260 ggcaatatgg tgctcagggt gcattcatca ctataacaga taaccatttt gttaatggtg 37320 ccctgcgcgg taactgaaat tgtactgggc tttcaacaga attttgtcaa aatgggacgc 37380 tgcatgagct aataagttgt gaaataaata gggttttatt gtggagtaat aagtaacaca 37440 aagaaggggg tttgcagtat cttaggaaga agaacagacg ttcttggtaa agttccttta 37500 atatgaaaat agcattttta aatacttgga gtagtgagtg aagaagcttt ctctatgaga 37560 gcacggttag ttcccaaata aatcccagcc tcctctcttc tgttaatttc ttcggaagga 37620 tttgaggtag cttttgaagt atttggtcaa agttgcaaac tcctcgggag gaggccaggc 37680 atggtacctc acgcctgtaa tcccagcatt ttgggaggct gaggcgggag gatcacctga 37740 ggtcaggagg tcaagaccag cctggtcaac atggcgaaac cctgtctcta ttaaaaatat 37800 aaaaatgagc tgagtatggt gatgcacgcc tgtaatccta gctacttggg aggcttgagg 37860 caggagaatc acttgaaccc agaaggcaga ggttgccgtg agatgagatt gtgccactgc 37920 actccagcct gtgtgacaaa acaagactcc tcctggaaaa aaaaaaaaaa aaaaaaggaa 37980 acctgagatt ctgcttaaca attgtaaagt cagaaggtat gaagagtatt tgaagttaga 38040 cctgtggaca ggctgattgg atcttcagca gtatgagaaa gtttagttaa gccaaggtac 38100 tatgtaaaac tccaagctgt acagagctct gcctggccag ctggtcagca cttgggtaat 38160 gaggaattga taaatggcaa attgcttcat tgaatgattg gattaatagt agcatgaatg 38220 gataaattaa cgggaatggg tatataaatg ggtatgagat caggaatatt aatggagtca 38280 caagtagatg atgcgtaaat gggactatat gtgtggattg atggatggat ggaccctgaa 38340 atgcattttt gatggaatta gggaacaaga ataaatataa taggaagtgt ggtatgcatg 38400 taagcatgtt tgtgtgtgta tgtgtatata ggttgatgca agagtggaag ggtagtaagg 38460 acaaaaactt tggacagcta tattgacaat gcaaaataaa aacatgaatg tatgaatgta 38520 tgaatttgac ggatatgtgc ttgaaagaat gaagtcagtt taggaaagga taattaacaa 38580 atctcagtaa tgattgtaat catgtgattc tcacagtaac tgttcaacag tgactgttaa 38640 ggatgctgcg tgctcatggc agtaactcat gggcagatgt cacaaagaca gtaatacctc 38700 ttattgcttt tatgacagca taaggtttta tttttcactg tggctttgtt agagttatgg 38760 aaagtcatcc attgcctctt aaatacgtaa tggtaaattg ggtaaaggaa ttgggtaaat 38820 cacatggttt tccaaaactt caggagattt agaagctgta ttttatgttt tctcaaggaa 38880 aggatgaaaa ggacacgtta aacactgata gtgtctactg taggatacct ttctggtctc 38940 acaaactagg tatactttct acttaaatgg aaactatccc cttcacagtg ggaaccaata 39000 aaaacctcac ccaggtaaaa atccagcgtc tcagtgatgc tatctcccta tcatgaggta 39060 attcacagta atctgtacct taagtctcag tgtacctact gttggcccag agataggtga 39120 aacttaaaga taattgtacc ttggctgcat gtagtggctc atgcctataa tcccagcact 39180 ttgggaagct gaggcgggca gatcacaccg tcaggagtta aagaccagcc tggctaacat 39240 ggtgaaaccc tgtctctact aaaaatacac cacaccctgg tgtggtggtg tgtgcctgta 39300 ataccagcta ctcagaacgc tgaggcagga gaatcgcttg aacccgggag gcagaggttg 39360 cagtgagctg agatcgtgcc attgcactcc agtctgggca atagggtgag actccatctc 39420 aaaaaaataa taattgaacc ttatttcctt ttgtacaatg tacaatgagc agagtcaggg 39480 caactataat acaactccaa actctaaggt gtcaaatgtg atagaaatca cttttccatt 39540 gaaattttga aatccctctg gaaatacact gtgaaggctc cctatactgt gctagagagt 39600 gttttactag ggcctggaag atgctcactt tttccttgtt ttccttggct gtagctttta 39660 cctctggcac actttcccaa tccccttatc ctacttaatt atttttaaaa taggcattgt 39720 ggaggatgtt tgttcatatt ttaagtctta atcatgggct tctagtttct ttggaagtaa 39780 aagtgaccca ttaaaaatgt aaaatgtgtt atgtgcatca tgggcacagg agtttcgtgg 39840 cctatatgtg attctaactt atatcttacc atggtgatcg tagaaccatg tgttgatatg 39900 taattttcaa aagaggtgaa tgcccttggc acagtaatct gtcatattta gcaaagcttc 39960 cctgagagcc atcataacag acccacagga atattttcat tagtaagaag tagatgtgtt 40020 cagccagtaa aattttgaag tggccatgac ttcaatctga gtacagaggg aaagttacac 40080 acaataattc agtgattggt ggataggtgc gttcaaggag gcagggttgg attggtgttt 40140 tcaagcttgg tagtagtagt agacaggcag acatgtgagt tgatggaagg atgcaagaat 40200 ggttactgaa attttctttg tattatatgg ttaatgtgga tttaataact agtcattgaa 40260 attatgtggg attggatatt taaagcccag aaagatgaat ataataatcg tctaatataa 40320 tttgaaatat aataacggat gcatgcaaaa ttgggtgtat tgaataatgt aagaaataga 40380 tggaaagtag aatatgagca aatggctgga tgcaagaatg gagaatgcag gttttaaaaa 40440 cctgttgggt gtatgtatgg ttatatgcac agtggaatca tttagtgaag gtgcagatgg 40500 ttatatgcct aggtgttatc attggatgga tcaaaaatgg aatgctgtat ggatagatct 40560 ttagattgat gagtacaaat atggctatct aaaaccttgg ataaatgtag ggatcagggt 40620 tcaggtacat tggttgcata agtgatagct gcctgtttgg tggctttaga gtggcttaat 40680 agactgatag atgggttgat tcacaaggtg atggtacagg aatttgatga ctatgagaat 40740 gggctgatgc aataataaag tcatatatgt aaagttgact ggaaagatgg acatttgaaa 40800 gccaatggta tattttcacg ggcagattca ttatgaaatt ataaaagttt tgtttttgca 40860 ttctcaacat gatgtgttag caaataagca aaaactaact gcagtgggtt cacaagttag 40920 tttaattaaa atgatctttc aatattttaa taatttgggg actttaggag gttgaggaat 40980 gagagaactt caccttctgt atattaactg gtcgtatgtc acaattttcc catatttttc 41040 acagttatag ctgaggtggt accagtttaa gaagtgagaa cttcttcact gactgaaatt 41100 tgcatatcaa tccaaatcat tgtgcttatt tactattttt gtagacgtca ttcttcaaaa 41160 gtgctggtaa gaatcagtaa ccctggtgta ctgtttattt ttgaccagtt tgatattgaa 41220 tctaatttgt aatattttaa aatccaaaac tatacatgaa ttctataaaa cacaaagttg 41280 tgaatttgtg gagtgattat cagttaggtg aaataaaaga gataaaaggg ctccctaaat 41340 tttgacacag ttttgatatg tagtttatgc aggttttgat ttaccagtct tatctactct 41400 caccgtagta tgtaatgtca tctggactga gactataact ttttatctgt atactcagta 41460 aattttatat tatttcagta aattttattg aataaatgct ctggaataaa ttcatcagct 41520 agagggagat aagaaggaag tctggcagcc tgtggaaaat aaagaaaatg gataggctat 41580 taaaagatgt cagagaccaa agtcattagg aattagaatt tactataaat agtatgggtt 41640 ataatgagag tagcaggttt aattttagtt ccaagtgcat gatttaggat atcatcagta 41700 agtaggtaag gtcagcagat aggagttgag gaatatttca acattgaagt ggtaaaagta 41760 gggtcttaac accctttctt tcgatgagtg aatgaaaaat cttcaactat tttccaacat 41820 tcctgttttt cttttttttc acaagcatct tcaatagtca aggaggacaa agacatcttt 41880 cctgcaggta aaatcattaa agactatatt gtgattttga agctgttcta tttgctacgt 41940 tgaggatata ttagattctt atttgagttc tttgaaatta aatttctttt ctcatacatc 42000 ctactttgtg gttatgtgat tattttgagt cgatatttta atcaaggact ttatagttaa 42060 ctcttgttaa taaccaacat ttaatgaaat caggcatttt cttgacttta gtaccacgag 42120 aagttgcaca agaagcatac agggtagcaa ggagaattga tgggtggata ctgggtttta 42180 gtttgtggaa agatcttaat ggaatacaca gagtatctta ttagtatttc cttatattgt 42240 gtcttttaaa aaaattctta acccctgaat tggtgtataa attagaatga agaaactaca 42300 caggaaatgc tggttcaaag aataaatagg tggttggttg gcgtgaaaat aatttggaat 42360 aggagatagg tattcaaatc acaaaaaaat gtgtagagaa acgaaggaaa atggcagctt 42420 tatcatttgc atacagtacg tatacctggt ttttgtaggt tttgggttat tccacatcag 42480 attgtaggag ttcggtttta tggagtatta cttgacttga agatgatata tttctgtcac 42540 caggcatggc tgtgtcataa cctgttgttt atttccattt gcaatctctt cttctgtact 42600 ctctcaggtg gtgaccatgt ggataatagg atcatagaca aatggtggtt ccatctacag 42660 catcaccgaa atgctgttgt tactgcttct ttctgggatc ttcttgcatc tttgcttcta 42720 aaggggcaca ccttttatag aagtacgtcc aggaatagaa gtgacctgct ttttcgcaag 42780 taattgcctg gaatgttttt atgtacttct ctgcactctc aatacatttc atgcttccct 42840 ctatttttgt atattaactc attgtatttc ttaaatttat attttacttt atgaatggaa 42900 gtgagatttg tgtatggtaa atataattaa ttcaacccca tggatacgtt agtcactgtc 42960 cagatgatgg caagtctttc tcagaagcag agggccttgg tgtgccagtg attttttttc 43020 cccatgtgta agatactttt tttcctcatt tgaatcagga gcccacagtt tttagacaag 43080 tcccaaatga aatcttaagc atttgtgtta tctggactag accttctgta gtatcctttt 43140 tgttagacct agtatatctc attgcagatc aggatctgag attgactata gttcacctct 43200 ttccaagtac acaaacttgg atgacatgac aactgagtgt gtaagggaga gcgagaccct 43260 tgcactgcca tttgagccct tgtgatctca tcttgtagaa catgttgtac aatcatttta 43320 ttggtatcat tagtgttatt tggggctgga ataaaaatct cagtgcacca aagagatttc 43380 ccctttatcc acgttaccct ggttttcctt tgttttctgt ttaacctaaa cgggcttaat 43440 ataaaatagt gcttatttgg tgttttaatt gtctgcttct ataacataag ctgcactgtc 43500 cattggggaa ctgctcacca tattgcccaa cctgtcttga taggtttata catgggaggc 43560 attcagtaat attaattacc tctctagacc agtgttagca ataacaaaca cttgctagaa 43620 ttttaagact atataatcaa tcactttgat gtcagttaat cctaccaaca caagattaaa 43680 ggtttaaaaa tctcatacgt gtacagccat tagtgtctcc tttcatacta tattattttg 43740 ttcattggca gctagatttt taggtagaac ttgtgttcct ttttgcaatg ctcatttatt 43800 ttacctggac agaaggtgct cttctgtctc ttctccaaag ttaatttatc tcatactatt 43860 tcttgtgtta atattttcca agttcagtat gctgttctgg ttataagaag atcagtgtcc 43920 taatcacaca cttttacatt atatgaaaca tcatacagag ttttgtagtc tgtataacaa 43980 tacacagagg tagcaaaatt tgtaaaagag cagactatat agtccatact gtagtaacta 44040 ctcaacattg ccattatacg tgaaatcggc tataaccaat tcataaacaa atgaatttgg 44100 ccgtgttcta gtaaaactta tttacaaaaa catgtgttag gccagatttg gaccacaggc 44160 tgtagatttc tgacctctgg cttacagcag aagtttatta tgatcctggg gaaggtggat 44220 atacatggaa ggcagaagcg agaagatgta ttccatccca tgtcattttt ctgaaccctc 44280 aacgtaggaa gttaaactaa aacatggggc agaatctgct ttaagccttt gaattcttgg 44340 ctcttaaagc caggttgagg gttatgtgtt tttattcttt tatatctcct tttcacttag 44400 gcttggcaac tagttcattg aaacagagcc aacaagaatg agtgagtcac tcagtgatat 44460 gaagcaagct gtggtcattt atctactacc ttccatacct acttcctagg tttgataagt 44520 agtgtttgta gtgtagttgt cagtaacttt tctcagctta cataagttta tgtggaattc 44580 atttacaaat gtgtgattat tacgatagat gttattttat aaatttcaag gttctttaat 44640 acagcatgga catgtttcta aatcaataaa tatagcttac ccacagactt tttatgggat 44700 gtaaagtatg tattacaaca ggtaaatcca tttctctgtt ttgggaaagc aggttaatgt 44760 tttgtttgtt ttgttgctgc atataatgtt gcactatata tatattctaa tgcagttggt 44820 ctcctaattc tacaggataa atgtctagct gtggcattgt tggatcatca gtttcgtttc 44880 agttagatgc tgtgaaattg ctcttgaaaa tggtgtcctc tgccaccaca gaacggtgtt 44940 gtaatggaag tgccaatttt cataaaaact tgtgtgcaac aggtattaag aatttttgag 45000 gtcgggcgca gtagctcacg cctgtaatcc cagcactttg ggaggcctag gcaggtggat 45060 cacctgaggt caggagttcc agaccagcct gaccaacatg gtgaaatccc atctccacta 45120 aatacaaaaa attagctggg cgtggtggca tatacctgta atcccagcta cttgggaggc 45180 taagacagga gaattgcttg aacccaggag gcggaggttg cagtgagccg agattgcacc 45240 actacactcc agcctgggtg atgagcgaaa ctccatctca aaaaaaaaaa aaagctttaa 45300 atttttagcc aatctaatag gtgaaaatgg catttttaac ataagtctga cttaaacaat 45360 taatggccgt ggctaaaaga agaatcaaat aatgatgtgt gatttataag ataaggaggc 45420 agtaccccat ttttcctcac tctacccaaa aatcctgttt atctgagcaa gaaatcatta 45480 atattttcta aatccgcttg gaagttcata aacgccctaa gtatacctta taccagcgtt 45540 tttatgactt tgtatttttg aaataatttt agattcagaa tcgcaagaat catgcagagc 45600 gacctgattt acgcttcacc tagattgact ttttattctg catcgttgtg ttcttccccc 45660 acttcctctt cttgctctcg cctcccttta tatgtttata catagcatta tcattttatg 45720 tactatttga atgatttgcc gacattatct tcctgtaacc caaaacactt caacatctac 45780 tttctaagag cctgagcatc ttatattgac ttcggtaaaa atttcaaaat aatgaaatgt 45840 gtcaatagta taaaagtata acagtatgca gtccatattc acattttacc catttttcca 45900 gaggtgttct ttatagcagt ttcttccctt ctacaacatc cagaaaagga tcttctattg 45960 cattcaatta tcatgtctct ttagttttgt ttaatctgaa acagtttcct ggactttgat 46020 cacatcagtg ttcttaaaaa gtaatagcta acagatttaa ggagatacct cagattttga 46080 attttgtgtt tcctcatgaa aaggtttaag atactcattt tgagcagaaa taattcagta 46140 ttctcagtct tccttagtga atcatctcag gtgacaaata atgtcacttt gtctcacttt 46200 gaattacttt gatctcttgg ttcgattggt gtccactgga cttttccact atagttaaca 46260 ttccttcata attaatttgg aactatacag gtattctatt tttcatcaaa cttccacata 46320 gtaggtttaa tatgcacagg tgacttttac ctgaatcagt gttgattaga aaaaaatctg 46380 ttattgctta gatgcattat ttagtatctt gtactgtaag gaagagtttg tatatcatgg 46440 cctgtcagaa cagtcccgca atgtgtttta tgaactgaaa attctgaaag aataaggtag 46500 tgatttatat gagaatacag ggaaagggtt acccaaagag tctaatgaat ttatgtctaa 46560 accatagagt ggaatgtgag agacacacag aactccagag ttgtgatgca aatacactgc 46620 acagtggaag gagaagagga agtttttggt aatagtgttt catctaatgt agctctgtaa 46680 tgtatgtgtg ccttcattat tggaagagtg ttcaacagtt cacagttgaa tagactgaag 46740 catgatgctg gaatctgggt tcagattcta gatccgtatc ctacatatca ccaatgcttg 46800 tttctcaatt tttgtttgtc attactttaa gtctctttaa tgcattagag tatccaaggt 46860 tgacagtgaa gggactgcat ttgggagcta tctgaagaca aaaacagctt tttgaagttt 46920 ctttcatacg tcaccttaca tggcctctcg cattctctgt ggagaagttt gtgtagatta 46980 ttcagactac cgtgcagtga ctgtgttgtt taaaacctat acatatccaa actctgtttt 47040 gtgttctcta taactagggc attagtctcc caatagtaat cctgcatctt atgctattta 47100 aagaaggttc ccagaataca gacattctta cttttgaaca atgacttggg tagattgagg 47160 aagtggtttt aataatcact ttgatatatt tcaaaatctg gttcattatt ggtgaggtgc 47220 aggccacctg gtattaatga aaatgtgtaa ttaggaacca gtgcagtgga atcagaggct 47280 tgaacatgac ctaaggcttg gtcaaaagtg gtgatctgaa tgttccctgc tctctgtatg 47340 taactttgta cttagtcttc agtggcaggg ttgcagcaga ggcccagtaa atattgttca 47400 ttcaacgtat gaaggagaaa atggaagtaa ggccaaaaat tactgattgt aaacaaatga 47460 agcaccaagt gaataaatgt acaaatagac aagtagccag taggaaaaaa aacaataatt 47520 gttacctaaa gaatgaaaac caagtggaaa aggccgccag ggacatttta atatgcatat 47580 tgttgctttc acatataata cagtaaggga gtatcagaaa acctgaatct gcctgactaa 47640 aacataccct gttccacaaa gctatatata tgagagtatt gaaggtggtt taataccaaa 47700 ttcaaaaatt cagcctcagt gtagcaaact tttaaatttt ccatgatata aagtaagttt 47760 taaccaacaa tggaagtcac agcactaaag tacattacta ttatatgatt ctctgatggt 47820 aatagaaact gtgctgcagg acacgttttg attcaggaag aaatgtggag taactccaca 47880 gaggaattca tcctttctaa gtttaaatct gaacggaacc catatgccca taccctgaag 47940 atgcatgtaa gggaacaaca tggcttggtc tgttgaaaaa agaaaagaac cttcaattaa 48000 gcattctgtg aacttgataa gaggatgcag aggaacgtaa atgcactctg catatctgtg 48060 attgaccttg gaacacagtg attgccctct aaagaatagc cgagtaagta ctgttatcat 48120 tccaccgatc aaattagagc ctcttccttc cagtgggagc agagtgacat agaccaagga 48180 aagccgagga gaagattgta gccttttatt tctccttata tttgttgagg ttcactgctg 48240 actgataaac gatttgcaca aaaaaattca ggcctctgac tcttctggta tttgatttat 48300 ctagtaaagt taattccaag acaaaagtac agttggttaa aaataccagt ctcatgttta 48360 tttgatggtt tgaaatattc tgttacattg ttgtatctcg tttgtcacct tggaatatat 48420 gacaatcatg ttatcttgat tttttccaca agataatttg attctaaaat cgattcattg 48480 tttatcttca ggaattagag attttaaaaa tgtcatctca tgtctcattc agtcatttcc 48540 aagatttagc gagtgttctc cctaatgcct tggataagaa tgccttgttc aatggctgta 48600 ttttactcat aattagcatt ccaactgctt tgggtttttt tagatttaca atttttattt 48660 ctgcagtact taactttcta tattttatgt atattaaaac aagttaggta ggatgaagat 48720 cactggatga tataaatact aatagcaaaa gtagaaataa gttgtattat ataagttgta 48780 cataggtgtt acattaggtt gtcttacatg aaagtattac aaagtatggg atttggggtg 48840 tattttgaaa tccttgccag ttctacttga taaagtattg aatggtatca tgtgagagga 48900 gaagaggacg gaaacaggac ttatgattta gacctcaaca actgctaggg agggttggtt 48960 ttctctgagt gcatgatttt ttataaaaat gctattttgc cagttttaga tccatattaa 49020 acccacagat taaggttttg gtttttaaag tgtaaatagg aagcttgagc tgggggggaa 49080 tttggaggta gagataatac ttaatcgctg tgggaaagga tgagatctag agatagagtg 49140 tatgtgggag taggaacata tgtgtctgag accatgcttt ggatgctcta gcatttagat 49200 attgagaaaa tgaggaagac ccattaaagg agattgtggc tagagttact ggtgaaaacc 49260 aaagggttgt agtgttcctg aagatacatg aagagtgaga ttaaaaatta atggggcagc 49320 agtggctttt gcatggcatt gaaaagacac agttcaattt gaaaattgag tatcattaat 49380 cgtagtgctc ttattattga aaaggccaaa tcaaacaata cctttgagtt gatggtctgt 49440 actataatta ggttaccatt gttagcccag catagacaca tgctgatacc tgtgagttgc 49500 tttcatcaat tagtatgtga agatgcatcc cagttgtaca attttagatc ctcttcatca 49560 ttccacatta tatgtataca agataaaact tgatgttttc attacatcct ttcaatcttc 49620 taacagcagt ccttacgtag ctttatcatt ggagtttcca cttgcagtgt ctctatctgt 49680 acctgcattc attggccacg gtagagtttt cattacggca ggattgcatt tcattgtttt 49740 ggcttgtgtc agacatttag caaagattgt tgaggaaagg aatggatgga aggggccagc 49800 tgaaagaaaa agtaacaacc taatgatgga taagtgaaaa aggaatgaag aaaggatggt 49860 gctaggaatc gagggagtaa agcaagatag aatgtacaaa aggtcgaatt tttaaagaaa 49920 gttgtagggc aagggcaagg tgtgttgaac ctacatttaa aatacaataa catcactaaa 49980 gtcgaggccg ggtgtggtgg ctcacccctg taatcccagc actttgggag gccaaggcag 50040 gcagattacc tgaggtcaga agtttgagac catcctggcc aacatggtaa aaccccatct 50100 ctactaaaaa tacaaaaatt agctgggcgt ggtggcgggc gcctgtaatc ccagttactt 50160 gggaggctga ggcaggagaa tcacttgaac ctgggaggcg gaggctgcag tgagccaaga 50220 tcatgtcact gtactccagc ctgggcgaca agaatgaaac tctgtctcaa aaaaaaaaaa 50280 aacccatcac taaaatcagg gagaaaaaaa ccatcactaa agtcagggat aaagtaccat 50340 tgtggaaggt gttcttttcc agcttaacct gaagaattgt acagtcattg tacattgtca 50400 ttccctaact aatgggttag atatgagtct gtagaaaatt gtttgtccaa catactttat 50460 gcctcttaac atttcactta ccaaatttca tttcattcct tcattttgtg tctaacagac 50520 tagaaataat gagctcctat tgacagggat attttcctct tcatactttc ctttacctta 50580 cagagccttt tatgtagcag atatttaatt tcataatggg tctaaactac ttgtttagac 50640 catggatgag tgaaattttg atgaatgagc cccaatcacc tgaagggtga gtaaaagaag 50700 aatttctaga gacccaatat gaagtagctg cttcacactt ttttgagaat gttatggcat 50760 gactgaggaa atcatagatg ctgtagacca tgttgagttg gattgtgtaa atatagattc 50820 tggtattagg gaactcagca tctgctggat tagacttctt atggtgaaag tcttttttta 50880 gggattaggc ataaatcccc actgatattt gtgcagtaat agagtatagc tcctgttttc 50940 tttcctgctt gtatagcctg tgccattagt gtcctctttc tcactgtttt ctcaaaggaa 51000 aacagtcaaa gaggaagcca tatgcatggt agactttgta atccgggaaa agtcaacata 51060 tttcatagta gtgcactttt tatgtgttgt cagtccttag aaaggattca ttttctccat 51120 attatatact actctatttt aaaaatttct tgggggagaa tggctgtaga caggccaatg 51180 atagaatcat agaatatagt cactgtctaa ttactttcaa tcaagagagg gaacaataaa 51240 gtacaatgta tgtcgctgac ttcagtgtga ccactcagta tttctgtaac acagtattta 51300 tattgctgta cggtagagtt atacttattt ctgtgatcca gttcatttgt ttaatattgg 51360 gattcaagga gtgttgaaga aatgtctact gattaataac agatgggaag agtgtatgtg 51420 ttttaaataa gagaccaaga gagacaataa ggaaaataag aaggaagtgt ttgtgaacct 51480 ttcacattac tcttacattc gggaagtcca caagacaccg tagtggagat tctgaggagg 51540 tgaaaacctg tagaaaaatg ctttattagt aaggagctga ctaagttgtc agaaagtgtt 51600 gatttttaga aggatattga gacattgggt atatagggta tatgactcct tgtcttcctt 51660 tcattctggc ttcttaccag ctgttgtgaa taagtttaag atttcttctg acgttataaa 51720 cttcagaaaa ggtatggctg tttgttcagt ttgaagtagt atcatatccg ccaaagcctt 51780 gttcaattgt cttgttgatt catggttctc ttcagtgata atattatatg ggattcctac 51840 ccacagccac ccaatatctc agtggagaaa tgcaggtttg gagagaacat ctgaatagaa 51900 tcacgctaag atggtacatt tgcactgaga ccattgttat gtggcaggca gacatgaagt 51960 atcctaggat tgatcagtat gccttaatgt aaatagctgc atatagacct gatttcttag 52020 gctccccact tcaagctctt gaatattgtg ttgatatcct tatcaataca ctttgtcttg 52080 tgttctgtgt tgtttttcca aaatataacg agctcctact tgacagggat tttttctttc 52140 tattgtctta cgataaaatg tcaagataaa aatgtatgag tttcattaaa gtttattgaa 52200 taaaatttgt gatggaatga gtgacagcga ggtcatgaat gagagagaat atggaaataa 52260 tggagaatgt gatattctga tagtcatgca atattctttt tgatataata tgtaacatat 52320 attagtatgt tatattctat gtattatttg tcatatatta ttactatatc ctgttgctat 52380 atttggataa tttgggaatc tgccatgttt gatgatgttg aaaagagaac ataaaatgta 52440 gtgatttctt aataaggtgt agaggtgtag gtattaactc tttaagaata tagtgattta 52500 ttttaaaata atgataggaa aggaccataa aaatgtctga atttgggaaa ttagaaaatg 52560 ttttctctct ggggctttca tatgtctgtt ctatgtgaat gtcgctttgc catggctccc 52620 tctttgctaa ctcttcttaa cccctgcaga gaaggaagtg tagtgatggt attttgagtc 52680 catcttcagg tttattggga atgcaaggga aatgagttgt taccaatggg agtaaagggc 52740 tagttgctat gccagtagct gctacttttg acactgcttg agcaatctga atggctaggt 52800 ttgaatctgg cttctcagtc agaattttac cttcactcta atgctgcttt ttttcaaatc 52860 acctatattt acataaatat gaaccaactt cagtgatctt aattctttcc cgaagatcca 52920 agtttctttc catctgcctg aagaactttc tttagcactt ctggtatagc agacctactg 52980 atgataattt ttcttttagt atatggtgat tagtttactt tttattcaac tgtgtctttt 53040 tttgaagtct tcttcattga aatatattgt tactaaatat agaattaatg gctttcttta 53100 agcacttcaa agataatcca ctgttttctg gactccgttg atacttaagt ctttattttt 53160 gtgtaattct ttttctttaa atgtgccatt tttcattttt ctctgactcc tacctactaa 53220 gatattttta cctaagtatt gagtcagttt tggttatgat gtgactcagt gtgtttttat 53280 ttatattgtt tggttgtttg aacttcttga atctgtaaat gttgtgcttt atgttaaatt 53340 tggggggatt tcagccattt aaaatataac ttttcagtct cttccccctg ggactccaat 53400 ttttacatat gtattagacc tattaatatt tttctatgga tacctgacat tctttttaaa 53460 tcttattttt ggtgtttttc actttgaaca acctaataat ttgtttccat ccatgttcac 53520 tcactgttta ttctattttt tcccaatctg ctcttaagcc tatcctgtga attttctttt 53580 taatttattt tattttttag ttccagatat tttctgcttt ttgtttgttt ttgagacaga 53640 atctttctct gtcacacagg gtggagtgca gtgtcatggt tcaccgcagc cttgacctcc 53700 tggtctcaag tgatcctctc accttaacct acccactcct aagtagctag aactacaggt 53760 gcatgccacc acgctcagct aattttttat ttttgtagag atggggtcgt tgtgttgccc 53820 aagctggtct tgaactccca gactcaagca gtcttcctgc ctcggcctca tgcccgcgcc 53880 aaccagttct ttatttttaa tattatgttg tatttgatgt gctatcctat tcatttagta 53940 taagcacatt tttctttatg tcttcagcat aattatatgc tttttcagaa ttttaacatc 54000 aggactgctt ccagggtagc tttattgccc tttgtcttaa gtatggatta tagttttcat 54060 tctttgtatg tcaagtaatt ttggattgta acttgaactt tgaatatact gtagaaactc 54120 tgaattctat tttattcttc taaaacaata tttctcagct tcagcactac tgacattttg 54180 aactgggtca ttttgtttgt gttgttgtgt gtattttggg agggtactgt tctatatgca 54240 ttgtggggta ctgagtatta tcctttgtct ccactcacta cttaccagta gcataactct 54300 ctctcctccc cacatcccct gccaaaaaat gccttcagtc ctttctaagc gctctttttt 54360 atggtgttgg ggccaaaatc atgcatcttt actcactctt tctcattgag agctatggct 54420 ataaagggta gtgatacttt tacttattta tttttaaggc aagcagttaa cttagctgga 54480 ttcaaactcc aggctgcctc gtgtgctgtg ggaagcagcc tacgctctat tcagttcttt 54540 tcttttcata ttggttgggt tactttgagt ctggcctaca tgatgggcag tttagaggtc 54600 aaccaaagga tttcagcaga acttatacac agaatttcat tcaggcttcc cgtgtctgat 54660 tggctacagt gtgggaattt cctcccactt ttcagccact actgaggatg cctttcggca 54720 aaattccttg aaattggaaa cttacaggga aattcctttc ctccaagagt gcgctctcct 54780 ccagtgttgg cttgcttttg gttgttctcc gtggttttag atagctgtct ttatattaat 54840 tctggagttt acagttgata tctgttgggg gcttagtttg ataacatgta ttcttctatt 54900 actagtagcc agacctgtat gtcttacttg acctgatgga gaaaagtttc aacttatgag 54960 acaatactgt gctagctagt tttactgatt tgtactctaa agtacccaag cctaaaatag 55020 tagagctgtc tatcccacat gaaacttctc tgattttcac tgttttttat aaaaagtata 55080 catgttcaca tttctgtagg tttttttaag catcacaatt tttataaact ttctatattt 55140 ccaaggtcta cctgctttgt attttgccta gtgagagttt tgtattcatg taggaataat 55200 ctcttggtgt gagtatctat tttccactca tccaaaacag atagagcatt gatttcacta 55260 agcgttatgt tctagtttgc tttggtatta ttattagaaa tacctggtga ttaatttgag 55320 ctaagtattc ttctctaccc tcattcccag cattatcacc cgcttttacc acttccaagg 55380 ggtggaagca ttctccacaa tgcatttttt catgccagag aaaaatctag aaaaaaatga 55440 ataaaacgaa gaaattcttt ccccttggta tctgtagcta acttgcctaa gtgttctttc 55500 ccacagttta agtcttcagt ccatagttca taagcaaagg ggtgtagcga gctctgatct 55560 tgccagaaga gagaataagt gagctacccc acggtggaca ttctggccat ctgaaatgag 55620 tcgatgcatg tggcttttgt ctaaaggcta caaataaaat gtaaccactt tcttctttga 55680 gtagttgata tagcaaatag ttgaaacaga agttttgatt ggcaaatcag gatgtggtag 55740 atactttaac aaagagtaga actattacca gttttatgtg ttgctgtttg tatctctttc 55800 acagttttga taatatcaca tcctggaaag tgaaacagaa aattattatt ccattttaaa 55860 tgactaaatt tgctttcatg gtatttacag tgaaagagta aattagaaag tgaatggatg 55920 actgttcatg agaaaaagca gggtaaaaag attttattta attaattgaa aatattaggg 55980 tcaaaacata ggcttatgtt atgttttgtg aattgtgctg tgttgtagac atttgatgag 56040 tcctaacata gaattgatct agctcttgaa ataccatttt tgattgagta taaatgggat 56100 ataggcacct tacaacttca gaattcgagg aagatgatgt gaatcttcca attttatcta 56160 tttgattcaa atggtatgtt ttttcacatt tctcataatt tccacgtcaa ctcccatgat 56220 gatcatgcag gaaagcagca tgattgcact tcttgtagtg cataccatca ctaaaacata 56280 gttactgtct ttctgtggtc ttaagaaaaa ttcagaaaca gcataccaat gtacatataa 56340 gataaataag cttatgtggt acagtaagtg ttctgttctg agaaatacct tgattcgtat 56400 cctaatgtct gatgttattg gtagttctca aacttcccca attctgcttt catctaaatt 56460 catcttatct atctattgtt aaataatcta tcagtccatt tttatctatc atctatatat 56520 ctgtctttat caatcattcg tctgtaatct atctgtgccg tttggcataa gagacagaag 56580 ggcatagcag tggaaactca aaggagttac ctccatgtga atggacagtg gtgatggtga 56640 tctgtgaggt ggtgatgtat agaaagaaaa actagaagag agcatgccct aactcaggga 56700 ccttgtccag caggcactct ggccttgtta tactgtgctt gaatatgaaa aaaaaaaaaa 56760 tcaaaatagt gctgacattc tttgtcttct gggtctgaga aaacttagag tagatatgat 56820 gactctgcca tttcagtctt ttgtatttcc acatttagag ctcagtttta attatgtaga 56880 attatttctc cagcctgtgt taaactagac catggattgg caaacttttt ttgtaaattg 56940 ccaaatacac attttcagtt ctgaaagcct tgtggtcttt gttgcagcta atctactctg 57000 ctgttgtgtt atgaaagcag ccataggtaa tttataattg aatgagtgcg ctgtgccttt 57060 cttccaataa aactttacaa aagcatcctg tgggctggag tttacccttt gggaaaccag 57120 agcattggct aaactggaac ctgaaaaaat aatcacatca actcagccac atggtaataa 57180 tatttagagt attatttcaa cattttcatt ttcataaaaa tttttttagc tcttttgcca 57240 aattccatct gtgagtgata caaatgacta ccacgtgcca ttaacatcac ctaaacagtg 57300 caaaacaagc atagtagaag taattggaat gatataaacc ccttgctgta atagttatag 57360 ttgataaatt atgtttcaaa attgaaccta tttcttccaa atttcatcta taaagttcca 57420 aggagttcca aaatcttgcc tgccttcttt tcccagttag cagtattgtc tctgagcagc 57480 catggtggta tccatcctcc ttggacaatg aatttagcct attttgactt catttgagca 57540 gttgtaattg tttcaccaca tcagagtaag attactacat gccagagcta ttctttaact 57600 cagcttgtaa aaacatgata gcatcaacaa tatacatagc aaatgaatgc catctttaat 57660 ccaattaaat ggtttttaca aatttgctct tgtttgttga tgctatctgc attgcagtaa 57720 ttaaaggtga ggtaaaaaga atgaataaac tgccaagtta aaattaaatt tgggcaattt 57780 ctcttttgca gtaatgtatg tatatttact caaaacatat gccaaattta gtgttgaaag 57840 gctcattcaa atcaattggg aaagcacgta aatgaacaat tcataaaaga aaagcattgc 57900 aaatggccaa gagcatagaa aatgtgctca atcttaccag tcattataag gaaataatga 57960 aatttgtgta tatatgaaat acttaaaata tatataaaat aaaacaatta tttgcctttt 58020 ttcacctatc agattaacag attatatgtg ttaacaaggt ggggagaatt tacaactcct 58080 gatatgttaa aatctttcag gaaggtagta gaaaatatat gtaagatgga aattagcact 58140 tttgaccaac aattttagtt ttagatattt acctataagg atataatagg aggtgttcaa 58200 agatgcatgt aactcaatgt agtattaatt ataattgtaa aatagtaaat aacatttttg 58260 tcaaatcata atgttaggaa aattagtgat ggcacattta accaattgaa ttatattcag 58320 ttctgaatac cgtgatgcat gttcaaatta attgatacaa aaatccaaca actttagcag 58380 tttgtttacc agttattgag taccaactgt gttcaacatt gttatttcac tcatatgaaa 58440 tgataaatgt atgtgcgtgt tatgatacgg tcaataaaac cacttttata ggaagaatac 58500 tcacaaaata cagcgagttc tggtcattat tttattgttg catttgtgtg tttgtgtgtt 58560 ttgaatacat acatgtattt caattaacta tagcatttat tgaattttta tcacatgtac 58620 cagatgggga gatcaacact ttacatgaat tataagttat aatataataa cttatataat 58680 gttattatat aataacttat tattataata acagatggaa taacgaattt gtctttttaa 58740 aagataagta aattgaggtt gagtttgaat tttgtaattc attctattat atagaagtta 58800 aataaaccta tcctaggatg tcacaacctt tggataataa taattaaaaa tacttatgat 58860 ttattaaacc cattgagcaa aatcatgttt tgtgaaagaa cccacatttc agaagtcata 58920 ttcattcttc ttttgtcttt aaggccagag acatgataat tattaagtgc agcttctcag 58980 gacagaaagt gtaagtgttg gtatattgta ggaacaggag aaaaacatga ataggaactt 59040 gtcttttgga aattcttaca gtataaacct ttaaggagtt acttctagaa atatggggtg 59100 cctttgctca ggatgtggaa caacatgttc ccgggcagaa accatattat acacaaagct 59160 ctgagacatc atggaggcac agatgaaagt ccaaagagaa atggccagta gaaagaggat 59220 cactaaatgg aagaagctaa ctttggaata gagctggtga caggtaatat gatgacttaa 59280 atgctgccaa tagcagggaa aaggtccatg gtaatatctg agtgaagaaa caattgccaa 59340 ctgatctaga tttgaagggc ataacctctt ggaatatttt tccagtgtaa tttgtgatca 59400 tatggtctgg attctacaaa atctccccca ttctacaaaa tctataatca gttctcttcc 59460 attttcttca ttcattctaa cccttttcta aagacggcac tttgtgtctt gtgaatgcaa 59520 tcccttagca gttctcagct agtagctgaa actttggtta aaatggtaag catgggggat 59580 tgtgacataa attttgcttt gctatggcag ttattgaaat atttttataa ttttgactat 59640 ttgtcatgta aggaatgcac agtgccattc taactgtgta tattctggta tttggggggt 59700 tggaaattga ctatatgaga ttcttgcagc tgggtctctg acatgttgag aatgctgaag 59760 aagaaaaagt acagaaggag aaagcagaga tggggaaagc tgcatccctc aaataggata 59820 ccactggata ctgagcagtg aacaacctct ggttttgtcg gacaccattt tggaatattt 59880 ggacacagtt tccggaagga tgagagacct aatcaatggt agtaagatgt ttaaaatatt 59940 attaatacga atgaatgctt aggcaaggtt gacggtaaag ctcttctgta caataggtag 60000 cgttaataaa gaaatgacaa gatttggaaa atcagtattt ggaaataatc ataattgttt 60060 cagccaggaa tcatcaaatg atgctaaaac ttggagaaaa ttttaagaga aacaggacat 60120 ttggtgtcct tatcagttac aaagggaaag tagtagcttc ctgatggaga acatggttga 60180 cagcacctga attaaagagg tgaaagttaa taccacagta gtgggaacat caggcagcgc 60240 tgataggatg cactgagaag aacacagtct catttctgta gtattactga ctaaactgca 60300 gaaacctgag tctacccatg aggaaacatc agtctcaaat tgactgatat tttgctttta 60360 gtattcaaac atactaattt cactgaggaa atggtccaga ttatttcaga ctatatagac 60420 atgagaatgg aatatcacat tggttcagga tgtctataaa aggataagga aggttggcaa 60480 aatttgaaga cagtccctca agtagattat agtgttacgt gagtattaat tgcctaagtt 60540 atataattgc ctgaggttat ataacagaaa attcttgttt ttaagaaatt aaaacaattt 60600 aaaggataaa gggataatgt catagctgta attttccaag catttggata aaataatata 60660 catgtttcaa aaaaaaaatg aaacagatgt tgtaagatgt tagcaaatag ggaatccagg 60720 tggaaataat ccaggaatta tggatagtct tgtatctgtt cagcaggtct gaaagtagtt 60780 gatgaaaata atgcaaaaga acatgtcaaa aagaaatggt ttgggcatat ggcttcaagc 60840 atacataaat gctcaggaaa catgaaaatg tgaaataaat ggatgagtac tataatacca 60900 gcaggccttg tagatacctg catttgaagc atttatatta gaaggaagcc tttttaccca 60960 gaattttttt cacttagcct aatgttttca aggtttggcc atgttgcagc atatatcaga 61020 tctccatttt ttttgatgga ggagtgatat tctattgtat aaatatatca cattttgctc 61080 atccactcac tagtttttgg ctattatgac taatcccgcc aggaatattt atgtggaggt 61140 ttttgtgtgt ttatgttttc aattctatta tacatgagaa tatagtaact gtgtttattt 61200 gacattttga ggacctgtct gtaagtgatg tttaagataa tttttgttac atttgaaggc 61260 agataatagt ctatgcaaaa tgaatattct gttgaatatt gatgtgaact attcttattg 61320 taaaaaaaaa gttacattga aatagtaagt atagaagtta tatcttggtg gcggggcgtg 61380 gtggctcatg cctgtaatcc cagcactttg ggaggccgag gcaggtggat cacagggtca 61440 ggagatcgag accatcctgg ctaacatgat gaaaccccat ctttactaaa aatacaaaaa 61500 attagctgtg cgtggtgatg agcgcctgta gtcccagcta ctcaggaggc tgaggcagga 61560 gaatcacttg aacccaggag gcggagcttg cagtgagctg agattgtgcc actgtactcc 61620 agcctgggtg acagagcgag actctgtttc acccaaaaaa aaaaaaaaaa aaaaaaaaaa 61680 gtattggttt ttgtactcaa caagcagttt tatgttttta tttttcagga actctccaat 61740 actgaattca ggctgggata ttagagaaaa ggaaaataca tgaaactcag tggtgtttta 61800 tggcactttg agttccccaa ttcaccttca aacatttagc cttccaagtt ctctgccacc 61860 gtatcagtgc atccctcctg agattcttaa ttctttgatt gtgtaaagat ggactatgct 61920 tactccatct tacttctctt aggtcttaca atggaagtgc cctattacat tttgttcttt 61980 tctatgattt ccaattattt tatgaaattt ttcatttatt ttttctgttc tttctatctt 62040 taatttctat gtaacttttt gaaatagatc tcaaagattt tatatatata tatatatata 62100 tatatacaca cacacacaga gagagagata tatatctact gtactattga agtagattcc 62160 taaagttttt atctcttcta gaatattggt ttcacaacac ccctattatg tgtatttaat 62220 tttacccacc acatggcgtt ttcaaaaagt ctttatttgg cggaatacaa cttcagaatc 62280 tgattcgaag agaaaattgc tcacagccgt gagccactgt gcctggccga tttttactat 62340 ttaaagaagg aagaatttta gcagcgtggg gtggctcatg cctgtaatcc cagcactttg 62400 ggaggctgag gtgggcggat cacttgaggc cagtagttca agaacagcct ggccaacatg 62460 acgaaacccc atctctacta aaaatacaaa aattagccag gcgtggtggc acgtgcctgt 62520 agtcccagct actcgaaggc ttaggcagga gaatcgcttg aatcagagac agggaggctg 62580 caatgagccg agattgcacc actgcactcc agcctgggcg acagtgcaag actccatctc 62640 aaaaataaag aggaattgga ggaggaaata aatgaataaa tgacaaaggt gacaaaggac 62700 caaagatctg tgacttgtgc aaagattgct ctgtggtaat tattacagaa acaatgtttg 62760 tatcttattt tttagggaat tttgtatatt gtctaatctg atttactttg tttttaatag 62820 tttgctgcag gtctagaaga tgtcacagaa tttcaaggaa gagaggtgag cagctgctgt 62880 ggtgattttg aaattgtttg tgtgtgttgt ggccagtgat gtcagaattt caggatctga 62940 gagttcatga ttttagaggc tcaaaggaga atatttttat aacttttttc tataattttt 63000 ttataatttt tttatatatt ttttataata ttttataatt ttttttgcta tgtgagtatc 63060 cctactttgt tcaaggaatc tcattatctt ttcccttttt ttaaaaaggg atttttttgt 63120 agtaacctga ataaattggg ggaagtattg atatatttcc ttttctcacc attttttgtt 63180 ggatgaaaat aatcttttag tgaaattcag tgtattaaat atttattttt taaagtctag 63240 agatggggtc atgctgtgtt tcccaggctg cccttgaact cctgggctca agcaatcatc 63300 ttgcctcaac ctcctgagta gctgggacta caggcatgtg ctgccatgcc tggcttaaat 63360 atttaaaaaa ttttatctgg cacattctga acacagatgt ttctacttat atttgtcatg 63420 tagtcacagt atatattgat tttgctacct cgcctactcc taaaagtttt aattcattta 63480 attggtctta attggactta aaaatttttt ccctggccgg gcgccttggc tcacgcctgt 63540 aatcccagca ctttgggaag ccgaggcagg cgtttgagac cagcctgacc aacatggaga 63600 aaccctgtct ctactaataa tacaaaatta gctgggtggg gtggcacatg cctgtaatcc 63660 cagctactca ggaggctgag gcaggagaat cacttgaacc cgggaggcag aggttgcagt 63720 gagctgaaat tgtgccattg cactccagcc tggacaacaa gagcaaaact ctgtctcaaa 63780 aaaaaaaaaa ttcccaatag attttaatct aattttatta gaacaattca gtcatatgtt 63840 ttttcatgct atgtatatga gagttccatt attcagatac taaacaaatg tctactgtac 63900 atttactctt ctcactgatg atggattaga taaccatgca caaaataagc ctggctgtgg 63960 aaatgcttat ttgttgggag ggtgcttgtt tggatcgatg atgagaataa ttgtctgagg 64020 atgctgaggg actcattcca gatgtcaatc tgaggtccag atgtgtggcc ctccaatagg 64080 acaaataaga ctctcagagc ctggctctat ttggggatcc ctcagtgaca acatagtacc 64140 tctgtgagcg tgccttttct atctctccga agagggcatt agcatcctgt cttatgagtc 64200 agtatgcact ttagtatggt tagtgaccca agactcactt tattttgttc attttgagca 64260 gagaattgta gatagataca tatatgggaa atatgttctt gattaacaaa tgaaaaaatg 64320 aaaaagtttc agtcaagaaa ggtcaaggaa ctgtgatgta tagtgaaggc agggaacact 64380 gcatgcctgt attaaatatt gacaaaggaa ccaattttag tgctttgtta tttttactgt 64440 tgagtatttt ctgagaccat ttctttttct tctattttgt tttgctgagg tagaggaggg 64500 ctggaatgag gtcctccact tcagaaaata ggggtgagta gttaaaccaa catcctttgg 64560 aattcatata cgtcatgcgt tccatgccac atcctgagat ctttttgttg atttttttag 64620 tggcttactg gataatatct aaatactgta tattttactt tggtgagtct ctccaccttc 64680 atttctgaat cattgtcctt tacattttta ttctatttga attttgcatg aaatgacaaa 64740 tgtagaattt tgcccaattt attttattta ttcatttatt tatttgggaa gacaaagtct 64800 ctctctgtca cccaggctgg agtacattgg cccagtcaga gctcacttca gctcttcacc 64860 ctgtagccct taactcctgg gctcaagtga tcctccaccc tcagcctccc aagtatctag 64920 gaatacaggt atgtgttacc acacatagct aatttttaaa ttttttattt tgtgaagata 64980 ggatcttact gtgttgctaa ggctggtctt gaactactgg gctcaagcag tcctcttgtt 65040 ttggcttccc aaagtgctag gattacaggc aggagccacc atgcctggca tcattaggga 65100 tattggtctg tgattcactt ttgatgatgt ctttggtttt gataaaaatt agggtaatag 65160 tagactcatg gaataagttg ggaaatgttt tctgctctcc tgttttttgg aagagttgtg 65220 aaggattgat gttatttctt taatgatttg gtagaattca tcagagaaat catttgtgtg 65280 gaattttatt tgtggaaact tgagtagcta attcaatctc ttgttaaagg tgacttcaat 65340 tttctgtttt tccttcttgt gacagttcct gtaatttata tatttctagg aatgtgccta 65400 tttaatctag gttatgtaat ttgttgacat aacttgttta tataagggtg ttagtctgat 65460 tttcatccca gattttatga aaattgggtc ttctgttttc agtagtgtag atatagttat 65520 gtcaattttt taagagacag agtcttactg tgttgtttat gctggccttg aacttctgag 65580 cctaagcaat cctgctacct ctgcatcttg agtaggtggg agtgtgggaa cacaccacca 65640 cacctggcct gtcactaaac aaacaaaaaa tttcagtgaa ccagcttttg atatttttat 65700 ttttcttctg tattttttat tttatttatt ggcattttat tcttatatct tttattctac 65760 ttgatttagc tttgctttgt ttttctgttt tcttaaggta aaagtttaga ttattgattt 65820 gagattttcc tttttttaat atggacattt acagctataa atttcccaaa gaactctttt 65880 agctacatat atattttctt ttgttgtgtt ttgtttcctt tgatttcaaa ctattttata 65940 aattttctta tttctcccaa gaactcccaa tgattcttag taatgtgtta atttccatat 66000 attgtgaatt ccccccaatt tttttccttt atttctgata tgattctatt gtggttggac 66060 accatacttt tctgatttct ttactttcag atttgttgat accagtgtgt ggtctaatac 66120 ctaccctgca cactgttcca tgtgcacttg aaaataatat attttctact ggttagattg 66180 ttccatagat ggatgttatg taactgtttt atagtgttgt ttgtcttcta tttccttgat 66240 cttctgtctc attgttatgt tcatcattga aagtgaggta ttgaaatttt cagttattat 66300 aatgtttatt ttgccttcca ttctgtcatt tttaaaattt aatttggggg ttatgttgtt 66360 ggatgcacgt atctttatta ttgttatatc ttcctgatgg attgacagtt taatcatcat 66420 gaaatgtcct ttgtctctac caacaatttt tttttttttg agatggagtc tcgctctgtt 66480 gcccaggctg gagtgcagtg gcaccatctc tgctcaccac aagctccgcc tcctgggttc 66540 acaccattct cctgcctcag cctcccgagt agctgggatt acaggcacct gtcaccacgc 66600 ctggctaatt ttttgtattt ttagtagaga cggggtttca ccatgttagc caggatggtc 66660 tcgatctcct gacctcgtga tccacccacc tcggcctccc aaagtgctgg gattacaggc 66720 gtgagccacc gtgcctggcc ctctaccaac aatttttatc ttgaaattta tttagcctga 66780 taattgtagt ttttgtctga cttatagccc ataaactctc tctggttact gtatgcagtt 66840 tatcttgtca ttattttact atctacctat ttttaattaa aacaaaatat ctttgagaca 66900 ggatctcact ctctcaccca tgctgtagcg caatggcatg atcatagctc actgcaacct 66960 gaaactcttg taattcaagc aattcttcca cctcagcctc ctgagtatct gaaactacag 67020 gccaacacca ccacacctgg ctaatttttt tgtatttttt ttcttgtaga gatgaaatct 67080 tggtatcttg cccaggatgg ttattttcta cctatttttt gtccttgaat ctaaagtgta 67140 tcttttgtag agagcatata gttgtatcat gtgttttttt aaaaagatac atctctgcct 67200 tttaagtgga gagtttactt catgaacatt taatgtaatt actgataagg taaaattcac 67260 atctgccatt ttctattttc ttttatggca tatatctgtt ttgtttttct tattgttctt 67320 tatgttaaat aagtaatagt gtactgcttt aattttcttt ttaatttttt gtgtttactt 67380 attagtggtt gcctttgaga ttatagttaa tttgttaatt tataatatag cttagattta 67440 atagttaatt ttaatagtac acagaaacta tttttcaata tagctctgtt ttctcaccct 67500 tccttttgta tattattgtc attcaaacat ttataccatc ttttatattt gcctaataat 67560 tattttactg gtcctgtgca tttcttcata tggatcaaag ttaatgtcta gtgctatttc 67620 acttaaggct gaagtctcca tttaattttt ctggtaggat aggtattttg acaaattcag 67680 cttttgttgg tttagaatgt catttctttt ttatttttga agagtacttt tgctgtttca 67740 agatctatgg gtagacagtc ttacttcttt ttctttaaaa tagtttgaat atgttatctt 67800 actgttttat ggcttcaaga gtttctgatg agaaatcagc tgttagtctc attgaggatt 67860 ccttgtacct gatgggtttg tttttctctt catattttga agactggctt ttgaaatttt 67920 tactatgacg tctccatgtc tttatgtgta tctcacttga gtgagtcaag ttcatttgac 67980 tcattttata tgtacatgta tgtttttccc ttacattaag gaaattttag gcgtttgttc 68040 ttcaaactgt ttctgccctt ctactgtgac ttttatgaac atgttgatat gctgtgttcc 68100 tcagttctct gaagctgttt ttcttttttc tttctgcttc acagaatgga tctcctcaac 68160 tgtcctgtat tcaaattcga ttaccttttc ctgctagctc aaatagtgtg attaaatttt 68220 tctagtgaat ttttattatt tatttctctg tatctttatt gtctagtaat tgatacattt 68280 ttaaaaaatt taaattttag gtttaggagt acatgtgcaa gtttgttata taggtagatt 68340 gtgagtcatg ttggtttggt gtacagatta tttcattacc caggtaataa gcatagtacc 68400 tgataggtag ttttttgatc ctcactctcc tcccaccttc taccttcaag tgctcccagt 68460 tacaagagag aatgtatggc atttagttta ctgttcctgc atcaatgtgc ttaggattat 68520 ggcctccagc tctattcatg ttgctgtaaa gaacatgatt tcattctttt ttcatggcta 68580 catagtattc caaggtgaaa atgctccata ttttctatgt ccagtctacc agtgtgatag 68640 ttaatattga gtgtcaactt gattggattg aaggatgcac agtattgttc ctggatgtgt 68700 ctctgtgaag gtgttgccaa aggagattaa aatttgagtc agtgaattgg gagagacaga 68760 ttcaccctca atctgggtgg gcacaatcta atcagctgca cagtctcatc agctgctggt 68820 agaataaagc aagcagaaga atatagaagg actagactgt ctgagtcttc cagccttcat 68880 ctttcaccca tgctagatgc ttcctgccct tgaacattgg acttcaagct cttgtactct 68940 tggacttaca ccagttgttt gcaaggggct ctcaggcctt cagcccacac tgttggcttc 69000 ccgacttttg aggttttggg actcagacta gcttccttgc tcctcagctt gcagaggaac 69060 tattatggga cttcaccttg tgattgtgtg agtccatcct ccttaataaa ctccctttta 69120 tatatacatc tatcctatta gtcctgtcct tctgggaaac cctgactaat acaaccagtc 69180 ctgggtacct gggttgattg tatgtctttg ctcttgtgaa taccacagtg atgaacattg 69240 aagtgcatgt gtcttttggt agaatgattt attttctttt gggtatatac cagaaatggg 69300 attgttgggt gaaactgtag ctctgtttta agttatttga gaaattctca gactgttttc 69360 ctcagtgacc ggactaattt acattcccac caacagtgtt taaacattcc cctttttctt 69420 caggcttgcc aggatctttc tcttttttgc ttttaataat agccattctg acgttgtgag 69480 atactatctt attgtggggt tttttttgtt gtcgtcgttg tttgtttttc gagacagagt 69540 cgcccagggt ggagtgcagt ggtgtgatct ctgctcactg cagcctatgc ctcccgggtt 69600 caagcgattc tcctgcctta gagtcccaag tagctgggac tgcaggcgtg tgccaccatg 69660 cctggctact ttttgtattt ttagtacaga tggggtttca ccatgttggc caggctggtc 69720 tcgaactcgt gaccttgagt gatccaccac catggcctcc cactgctggg attacaggca 69780 tgagccaccg catcgggccc ttatggtggt tttgatttga atttctctga tgattagtga 69840 tactaagagc attttttcat atgtttgttg accattctat atcttctttt gaaaagtgcc 69900 tcttaatggg gttgattttt gcttgttgat ttatttaagt gccctataga ttcaggatat 69960 taggcttctg tcaaatgcat agtttgtcaa tgatctctgt tcgccaatga tatggttcta 70020 tacctagaaa atgccttctt taagaaaata aaattgtatt ttgtggatgt atcacatttt 70080 ccttatatat ctgctttggg catttgggtt gcttctgcct cttgggcatt atgaataatg 70140 ctacagtgaa tatggatatg cagatgtatg tttgagatct tgctttgaat tactttggat 70200 atatacccaa aagtgggatt cctggatcat atggtaattc tattgttaat ttttcaggaa 70260 cctccataca tttttccaca atggctgtac cattttatgt tcccatcaac agcatgcaaa 70320 ggttccagtt tctccacatt gtcaccaaca cttgctgttt tttatttcac tcttgttgcc 70380 caggctggag tgcaatggca ctgtcttggt tcactgcaac ctccacctcc tgagttcaag 70440 cgattctcct gcctcagtct ccccgagtag ctgggattac aggtgcctgc caccatgccc 70500 agctaatttt tatattttta gtagagacag ggtttcacca tgttggccag gctggtcttg 70560 aactcctgac ctcaggtgat ccacctgcct tggcctccca aagtgctggg attataggcc 70620 tgagccacca cgcctggctc gttgtttttc aattgtatct tctaatggat gtgaggtgat 70680 acctcattat ggttttgatt tgcatttgtt tagtaattag tgatactgag catgttttca 70740 tatacctgtt gtccatttgt ttatcttctt tggaaaaaaa tctattcaat tactttgccc 70800 cttttttaaa attagggttt tttgttgtaa tctgagtttg ttccctccct ccctcactct 70860 ctccctccct ctcttccctc cttccctccc tccttccttc cttccttcct tccttccttc 70920 cttccttcct tccttccttc cttccttcct ttcttccttc cttccctccc tccctgtctc 70980 cctccctgtc tccctccatg tctccctccc tgtctccctc cctccctccc ttcttttctc 71040 ccttcctccc tcccttcctc cctccctttc tcccttcctc ccttccttga tcacatccac 71100 atccttcctt ccttcgtgct gtgttgctca gcatggagag cagtgccaaa atcatggctc 71160 actgcagcct caactttcca ggtgccagag agcctcccac ctcgtgctcg tgggaccaca 71220 ggcacatgcc aacacgtcta gctaattgtt ttttaatttt tattttttgg tagatatggg 71280 ggtctcactg tgttgcacag gctggtttca aactcatagg ctcaaggaat cttcaaacca 71340 tggcctctca aagtgttgac attacaggca tgagttacca tgcccatcct gcatgtgaaa 71400 gccttacgag atatgatatg caaatatttc tctcatttgg tacgtttcct ctttcattct 71460 gttgattgtt tcccttcatg tacaaacatt ttaggtttga tgtagtcttg cttgtctgtt 71520 tttgcttttg ttggttatac ttttagtgtc acattcaaaa acttattgac aaaaacaaga 71580 agggtttcca tgtgttttct tctagtttta caatgtcaag atgtatcttt aagtacttaa 71640 tttattttga gttgattttt gtgtatgttg taaggtaagg attcagttta cttttttttt 71700 ttaatttgcg gatatccagt atgccaaata tgattagtta gataaactgt gctctgagca 71760 cccatgtcaa agataaattg agtagagtac atggatttat ttctgcattc ttcattcttt 71820 tccattagat tatgtctgtt ttttgccagt attctagtat tttgaattac tatagctttg 71880 ttatatactt ggaaatcaag aagtgcctcc acctttgtgt ttcatgctga atattgattt 71940 agctattttg gttcttttgt ggatccagat aaattgtatg atttttttct ctatttctgg 72000 aaaaatgtga ttgtgatttt gataggaatt atagtgaatc agtagataac tttgggtagt 72060 atggatattt tgacaatatt aattagtccc agtggtggtg ttgaggccgt gttgacctgg 72120 aggcactggg gtcagtgata gtgttgtcaa gttggctgca ggatgggatg gtgcctggga 72180 ggtcagtgca taaaaatcct atggatgtga tcaaggaaag ggtgatggaa ggtgatgtgt 72240 cctgtctgct tggtccttgt aggatcaggc aggacatcct gtaataaaag gagacattac 72300 cttcggatgt cctgagggca tggtgcaggc accaggactg agtggagggg aggaagctca 72360 tgtcttgagg tcctttggct acatggggaa gactgtctct gggcttgatg ctgagttcca 72420 gactgacgtg ctggctgttg tgatggtgct ctccagtgct ggttgtggtt ggtttttggc 72480 taggtacacc tcacctggga cagtggccaa agacagtgtc agttccagac atcagaagcc 72540 ccatgaggaa gagcatgtgc tcgcgccagg agtggtggct gttaggggag ggacctcaga 72600 cctatgtctg catggcctga ggtcagagtt cacatcctac tgattgaaga ccttgttctt 72660 gagctgtccg gttgccacag ggtcggacct ggaggctgca gaccatcgtg gccctttgca 72720 gtgttcggaa acatatgcgc accccaggga gggacacaca cacacacaca cacacacaca 72780 cacacacaca cacacacgca aactcacaaa cacaacacac agacagaaaa tgacaaataa 72840 acacacacac tcacacacac acacacagga gcccacagaa aaaagcaaat agacgcagaa 72900 acgggcacgt gcagtagttc tggccacaca tgttccctag gtatccacag aatggcatgg 72960 gtattgtata ttcataaaga tggagatcag tcatggaggc caaggacaag taggtgcact 73020 ggttgaacta cagtagagaa tggcatggaa gtggtgagca atggacctgg gcctgtttct 73080 caagtgtgta tttgatttct ttacaattcc ccggagaagt tgtcatggga ggccagccgc 73140 ctgctggcaa ggaagatggt tgattcttct gatcaatgga ggccctgcag agtcctgtag 73200 tcactgtggc ctggcatcca tggtgcaccc aatgctggtg gatggcttag gacggtaagc 73260 attcctctgc cccacgtgct gaatgagagt ggcttttgga tgtcctatac cttcaaggag 73320 ctgtttgtca gcagcgaatg acatggcaag ttccactcct agagtggatg gtctgtgccc 73380 attgctcagt ggtgcagctc tggcttcccc agcatgctga atgtctttaa ggtcatcagc 73440 tcgccccttc ccagcctgtg gtgtcaaatg tcttgcccct tgtcaaatgt gcttggatcg 73500 atgatgagtc ccctataaaa acattccttg gaaaagctga acaaaatgag tgagaactca 73560 taacgtcatt ctcatcggaa ctgaggtcca gcatgttgct tcctctgggg cctgtaggag 73620 tgagggacaa cttccactga ttcccatagg ttccaccacc cagggcatcc acagacaaaa 73680 gtctcgtgtc acaggcacgt taggaacatt ccctctgtgt gaggtacatg ggtgggagag 73740 tgatggggga ttcggccgct ctgtgatggc gtggtggccg tggaagcagg cagaaatgtt 73800 gcaggcctag gggaagtgga aatgttgcca gcacaggggt gtgtgctact ggtaagctcc 73860 cagaaggaag acccggacct cacagtggtc atctcagtgc agaagaccag gtgtctgttt 73920 tcatgtcgag gagagcccaa ggcccagacc tcaggcagac cttggtgttg atttttgatt 73980 agttgagaac aggggagtgc caaggtgtta ggggagagtg cagagcaata ggtgtcgggg 74040 caaacagtga aagcctcttc agcctaccct gcagcattgg tcaccaggag ccctcctgga 74100 agggatttct ttgcctcctg agctgtgaga tgcctgtggt gcagtggcag aggcctaggt 74160 aggaaggtac tccaggggaa aggtggtaga gggatcacat ggacatgagt gtcattagca 74220 ggcttgggct gtcattcagg ggtgatgggc ttcccatgga tttttctggt ggaagacagg 74280 ttggccagca ggggtcttcg aggccaggtc ctggggagca cgaggatcga gttggtgccc 74340 gtggccctgg gtcacttcca gtcttcccag gagagtaatg ggctcctcca ttgtgcaaat 74400 cttcctataa atggtctctt ggcccgccat tattgggcgg ctccacctgc tgcagcttgt 74460 atgagcaaat actgctctgg atcctctttc ctgcttggaa agcagcttca gtcctgaagg 74520 tccagagtga atgtgccctg accctggctc tggcccaagt ctgtgccgta ggtactcgtc 74580 acacttggag ctatccatgg aggtctgtgt gcattccagg caacacgggt gcaatcccag 74640 gggtgctgcc acagagtcct tttacttggg atgcctcaca cctctgcatg ttggcaatat 74700 ttaagtgttg gagtccacta caccctaggg gtgatgaact gttttggctc ccttaaccgg 74760 tttgaagtct cagcgcagcc aggacagcca tgccatgttg aagggcatgc agatggctta 74820 ggaatgttgg aaaggatggg tggttctgag ctcgcagctc actcactagc tgcatgcatg 74880 tagacccagt ggtggtgttc aggtagtgtt gactttgagg cattgcggcg ggtagtagtg 74940 cagtcaagtt ggctgcataa tgggatgttg cctcagaggt cagtacagga tagccctgtg 75000 ggtgtgtcca atgcaaggaa aatgaaaggc agtgtatccc atccgcctgg tccttgggac 75060 atcggtaggg gggacgtccc attggaaaag cagccattcc gtttgtgtgt cgagagggca 75120 tagtgcaggc acatggactg agtggagggg aggaaggctg tgtcttgagg tcctttggct 75180 agattgggaa gaccacctct ggccttgacg ccaagtttca ggctgatgtg ctggccattg 75240 caaaggcgcc ctccagcaca ggttgtgatt ggttttccac caggtacgcc tcacctgaga 75300 gggcggctag agacagtgtc tgctcaggac atcagatgtc ccgtgaggag gagtgtgtac 75360 tcacaccagg ggagttgact ggtaggcgag ccaccttggg cctatgtccg catggtctcc 75420 aggtcaaaat tcacatccta ctgattgaag gccttggtct tcagctgttg ggttggcgtg 75480 gtgtcaggcc aggaggctgc agactatgac tgcctgttgc agtgttggga aacacacatg 75540 ttaggaaaca catgtgcatg agggagacac acacacacac attcatacac acacacacac 75600 acacacagag gcatgccgag ccacaggcaa atacatgcag caatgggcgt atgtgaccac 75660 gtgcactttt aggtatccac agagtaacac atgtaagata tattcatgga gatggaggtc 75720 agtcgtggaa gccaaggaat aacgggtgtg caagttgccc aacgggaaag aatgggattg 75780 aagtgttgac cagtggacct gagcccattt ctcaagcgtt tatttgattt ctttacactt 75840 ctcagaggca gttgctgtgg gaggtgtggt aactgctgga aggaagatgc tcaattcttc 75900 tgagcaacga aggccacacg gagtcctgga ttctgtgtgg cctggcatcc atggcgcact 75960 gtgtgctggc aggtggctca ggacggtaag catttctctg cccagtatgc tgaatgaggg 76020 tgtctttcgg atttccaaga cccgcaagga gcagtttctc agctaaccac taatggcatg 76080 gcgagttcct ctcctagagt ggatagtctg tgctcattgc tcagtggcat cgctctagtg 76140 gggccgaagg tctttaaggt cattggctca cccactgccc agcctgtggt gtcaaatatc 76200 ctgccccttg ccccttcaaa tgtgcttgga tcgatgatga gtccccaaaa aaaacattcc 76260 ttggaaaagc tgaacaaaat gagtgaaaac tcataccgtc attctcatcg gaactgaggt 76320 ccagcacgtt gccttccccg gggactgtag gagtgaggga caacttccac tgattcccat 76380 aggttccacc acccaaggca tccacagcca aagtctccca tcaaatgctc attaggaaca 76440 ttcccttttt gtgaggtaca caggtaggag agtcctgggg ggaacggctg ctctgtgatg 76500 gcctggtggc catggaagca gacagaaata tcgcaggcct agggtagtgt gcgcctgatc 76560 ttggcttggt gagctcctag gaagggagac gcggacctcg tggcaggcgt ctctgagcag 76620 aggactgagt ccttgttttc ttgccgggga gagcacaagg cccaggcctc aggcagatgt 76680 tggtcctgat ttttgattag ctgaggacaa gggagtgcca agggtgatgg gggacagtgt 76740 ataacaaagg gtgttgtgac agagagccaa agcctctttg gccctccacc cagcatccag 76800 tcatggaggc cccccagcag ggatttcttc atcccctgag ccgtgagatg cccctggtgc 76860 tatggtggaa gcctggactg gaaggtactc cacagaagag gtggtagggg gcttatgtgg 76920 acatgtgtgt catcagcagt cttgggctgt tgttcagcgt tgatgggctt tccatttatt 76980 tctctagtgg atgacaagtt ggccagcaga ggtgtcagag ggcaggttcc agggaataca 77040 agggtcagac ttgtgctcct ggcccttggt cacttctcgt cttcctgaca gagtagtggg 77100 ctccactgtt gggcacatct tcctggaagt cgtctcttgg cccgccattg ccgagcggcc 77160 acacctgctg cagctcgtgt gagcaaatat ggctctggat cctctttcct gctttgaaag 77220 cagcttccat cctgaaggcg tccagagggt atgtgtcctg gccctggcca ggaactctgc 77280 tgtgggcatt ggtcacacgt ggctatccat ggagatccgg gtgcattcca ggcaacattc 77340 taggggcctg ccatggagag ttcgttgact tgggatgccc ctgcacctcc catgttggtg 77400 atgttccagt gttgcattct gctacaccct aagggtgatg aagcatttca gctcccttaa 77460 acagtttgat gtcacagtgc agccaggaca gccatatcat gttgaggggc ccacgactgc 77520 attaggaatg ttggaaggga ttggtggttc tgcagatcgc agctcattag tagctgttta 77580 cttgtagacc tggtgatggt gctgaggcag tgttgacttg caggagttgg gatgggtggt 77640 aatgcagtca agttggctgc atgatgggat gttgcctcag agttctgtgc agagaagccc 77700 tgtgggtgta accagtgcaa ggaccatgga aggcagtgtg tcctgtcaac ctggtccttg 77760 gggaagggac gtcctgttgg aaaacagcca ttcccttcgg ttgtcctgaa ggtgcagtgc 77820 gggcatgtgg actgagtgga ggaagcccgt gtcttgagat cctttggcta ggttgggaag 77880 attgcctctg gcttgatgcc attttcagac ctatgggttg gtaattgtga aggcgccctc 77940 acgtgctggt tgtggttggt tttccgccaa gtgagcctca cctgggagtg cagccagaga 78000 cagtgtcagg tcacaacatc agatgcccca tgaggaggag catgtgctca ctccaggggt 78060 ggtggctgtt aggtgaggga cctcaggcct atgtcctcct ggcctgattt tacatcctac 78120 tgattgaaga ccttggtctt gagccttcgg gttgcagggg cttcaggtct ggaggctgca 78180 gactatggcc tcctgttgcg gtgttgggaa acacatgtgc atgagggaaa cacacataca 78240 ctatcacaca cacaaacagg cgctcacagc cacaggcaaa tatacgtagc accacgtgcg 78300 tgtggtcgtt ccggccacac gtgcttccta ggtgtctaga aagtgacaca gtcagataca 78360 tttataaaga tggaggtcca taatggaggc caaggagaag cgggcatgtg tgttgctctg 78420 tggaagagag tggcgttgaa gtgaccagtg aacctgggcc catttctcaa gcatgcattt 78480 gatttcttta cacttctcag gggcagttat catgggacac ccgccatatg ctggcaagga 78540 agatggtcag ttcttctgag ccacaaaggc ccccaacatc ctggagttgg tgttgcctag 78600 catccacggt gcgccccctg ctggtggatg gctcaggatg gtaagcattc ctccgccgca 78660 catgctgagt gggggtggga tttccaagac ctgcaaggag ctgtttctca gcaggccact 78720 gatggcatgg cgagttccac tcctaaagtg aacggtctgt gcccattgtt cagtggtgca 78780 gctctggctt ccccagcgtg cggagggttt ttaaggtcat cggcttgccc actgcccagc 78840 ctgtggtgtc aaatatcctg ccccttcaaa tgtgcttgga tcgatgatga gtcccccata 78900 aaaacattcc ttggaaaagc tgaacaaaat gagtgagaac tcataccgtc gttctcatcg 78960 gaactgaggt ccagcacatt gcctcccccg gggactgtag gagcgaggga caacttccac 79020 tggttcccag aggttctacc actcagggcg tccatggatg aaagtctcac atcacaggca 79080 caatagaaat attccctctg tgtgaggtat acaagtagga gagtcatggg gggattggct 79140 gctctgtgat gtcgtggcaa ctgtagaagt gggtggaaat gcagacctag gggagtgtgc 79200 ggctggcctt ggcttggtga gctgccagga agggagaccc tgacctcctg atgggcctct 79260 ctatgtggcg gaccaggtct tttttttatg ccaaggagag cacaaggccc agacctcaga 79320 cagaccttgg tcttgatttt cagttatctg aggagagggg agtgccaaag tgatggggga 79380 cagtggagag caatgggtgt tgtggcagac agccaaagcc tctttggccc tccccccagt 79440 gttggttaca ggggcccctg gcagcaattt ctttggctcc tgagccatga gttatccatg 79500 gtgtggtggc tcagcctggg caggacagta ccccagagaa aaggtggtag agggctcaca 79560 tggacacgcg tgtcatcagt ggtcttgggc tgtcatttgg cagtgatggg ctttccatgg 79620 atttctattg tggatgacag gttagccagt ggggccttca agggcagatc caaggagcat 79680 gagtgttggg ctgtagcccg tggccctcgg tcacttctgg tcttcccggc agaatagtgg 79740 gctccaccgt tgtgcacatc ttcctggaaa tggtctcttg gccctccatt gctgagcagc 79800 cccacatgct gcagctcttg tgagcaaata actgctttgg atcttccgtc ctgctttgaa 79860 agtggcttcc atcctgaaga ctttcagagg gaatgtgccc tggccctggc cctggctcgg 79920 aactctcctg tgggattcgg tcacacttgg agctgtccat gggggtctgt gtgcagtcca 79980 gacaatgcat atttaatcct aggtgccttc catagagagt cccttgattt gagttgcctc 80040 tactcctctg catgttggtg atactcaagt gttggattta gctacgccct aggtgtgatg 80100 aactgtttca accccgttag tctcagcgta gccaggatag tcatgccatg ttgaagggca 80160 tgcagatggc ttaggaaagt tggaaaggat tggtcattct gcggctcgtg gctcacttag 80220 tagccatgtg catgtagacc tggtggtggt tgtcagatgt cgttgagcag gtgttgggga 80280 ggatggtcct gcatccaagt tggctgcgtg gtgggatgtt gcgtcggagg tcggtgcaag 80340 gaaggccttt gagtgtgatc gatgcaagga tgatggaagg cactgtgtcc tgtctgcctg 80400 gtgtttgggg cgttaggcag ggatgtccca tgggaaaagc agccattccc tttgggtgtc 80460 ctgaggacat ggtgcaggta catggactga gtggaggaga ggaagcccgt gtcttgaggt 80520 catttgccta ggttgggcag actgcctgtg gccttgatgc tgagtttcag agtgacgtgc 80580 tggccgttgc aaaggcgccc tccagtgctg gttgtgtttg gttttgtgcc aggtgtgcct 80640 ttcctgggag tgctgccaga gacagtgtct ggtcacgaca tcagatgccc cgtgaggagg 80700 agcttatgct caggctaggg atggtggctg ttatgtgagg gcccttgggc ctatgtctgc 80760 atggcctcga ggtcagagtt tacatcctgc tgattgaagg ccttggtctt gaattgttgg 80820 gttggtaggg gctcaggtct ggaggccgca gactatgact gcatgttgcc atgttgggaa 80880 actcgtgttg ggaaacacat gtgcatgagg gagatacaca cacacacaca cacacacaca 80940 cacagccact cagcaatgtg tgtgtgcgcg gtcggtctgg cgccacacac agctccaagc 81000 tgtttgcaga gtgccactgg taaggtacat tcatggaaac agaggtcact catggaggcc 81060 aacagaagca aggcgtgcaa gttgccacgc atgaaagaat ggcactgaag tagtgaccag 81120 tggacctggg cctgtttctc aagcgtacat ttgatttctt tatacttctc aggggcagtt 81180 gccgtgggag gcccgctgcc tgctggaagg aagatggtca gttcttctga accacaaagg 81240 ccctgcagag tcctggagtc tgtgtggcct ggcttccagg gttcacctca tgctggtgga 81300 ttgctcagga tggtaagcat tcctctgccc catgtgctga gtgacggtgt cttttggatt 81360 tccaagaccc ataatgagct gtttctcatg aggccactaa tggcatggtg agttgcattc 81420 cttgagcaaa tggtctctgc cttttgctca gtgccatggt tctatcttcc ccagggtgcc 81480 gaaggtcttt aaggtcgtca gctcacctac tgcccagcct gtggtgtcaa atgtcctgcc 81540 tcttcaaatg tgtttggatc gatgatgagt ccccccaaaa aaacattcct tggaaaagct 81600 gaacaaaatg agtgaaaact cataccgtcg ttctcagcgg aactgaggtc cagcgcgttg 81660 cctccagcag ggactgttgg agtgagggag agcttccact agtccctata ggttccacca 81720 cccagggcat ccgcaggtaa atgtctgcca tcacacgcac attaggaaca ttccctttgc 81780 gtgagataca ctgttaggag agtcacggag ggattggatg ctgtgtgatg gcgtggcagc 81840 tgtggaagtg gacggaaaaa tctcaggcct agaggagtgc gtggcactga tgagctccca 81900 ggaagggaga cccggacctt gtgtcaagct tcctcgcaca caggaccggg tcctggttcc 81960 cctactacag agagtatgag gtcccagcct caggcagacc ttggtcttga ttttcagtta 82020 gctgaggaca ggggagtgcc aagggtgatg gggaagagtg cagagcaatg ggtgttgtag 82080 cagatggcca aagcctcttc ggcccttccc ccagcgttgg tcccagggtc accccagcat 82140 ggatttcttt gcctcctgaa ccgtgagatg cccatggtgt ggtggtggag acctgggtag 82200 gacatattct ctggtattcc agagaaaagg tggtaggggg ctcacatgga caggtgtgcc 82260 atcagtggtc ttgggctctc atttggtggt gctgggcttt ccgtgtattc ctctgatgga 82320 tgacaggtcg ggcagcaggg gtcttcaagg gcagttccca ggcgtgtgag ggttgggctg 82380 ctgcctgtgg ccctgggtca ctccgatctt cctggcagag taatgggctc caccgttgtg 82440 tacatcttcc tgtaaatagt ctcttggccc gccattgcca ggcggcccca cctgctgcag 82500 cttgtgtgag caaatactgc tcttgatcct ttttcttgct ttgaaagcag catccgtccc 82560 aaaggcatcc agagggaatg tgccctggcc caggcccagg accctcccgt gggttccaat 82620 catgcatggg gctgtctgtg gaggtccgtg tccattccgg gcaatgcgtg tgcaatccca 82680 ggggtgttgc cacggaaagt ctcttgactt gggatgcctc cacgcctctg catgttggca 82740 atgttccagt gttggattcc gctactccct atgcatgatg aagcatttta gctcccttag 82800 ccagtttaaa ttcacagtgc agccaggaca gccgtgccac tttcaagggc acttggttgg 82860 cttaggaaag ttggaaagga ttggtggttc tacagttctc agttcactta gtagctgcat 82920 gcatgtagac ctggtggtgc tgatgcagtg ttgacttgcc agtgttgggg tgggtagtag 82980 tgcagtcaga ttggctgcat gaggggttat tgcttctgag gtcggtgcag ggatgccctg 83040 tgggtgtgtc caattgaaga acgatgacag gcagtgtgtc ctgtcaacct ggtccttggg 83100 aattcaggta gggacgtcct gttggaaaag cagccattct ctttgggtgt cctgagggaa 83160 cggtgcgggc acatggactg agtggagggg aggaggcatg tatcttgagg tccttttgct 83220 aggttgctag tcctacctct ggccttgatg ccaagtttca gactgacatg ctggactttg 83280 caaaggcgcc ctctggagct ggttgtggtt ggttttccgc caggtgcacc tcacctaaga 83340 gggtggccag agacagtgtc ttgtcatgac atcagaagcc ccatgaggaa gaggaggagc 83400 ctgtgctcct gccagaggtg gtggctgtta ggtaagagac ctgtgacctg tttccacatg 83460 gcccggaggt caaagttcac atccagtgat cgaaggccag ggtcttgagc catcggattg 83520 ctggggggat caggtctgga ggctgcaaac tagaactgcc cattgtggtg ttgggaccca 83580 catgtgcatt agggagacaa acatgcccat ttaaactaac attctcacac atgcacacac 83640 ccacacccac ccatacacac acactctcat acactcacac tcaaactcac actctctctt 83700 tcacacacac acacacacac acacaggcac agacagccat aggctaatag atgcagcgat 83760 gtgcacatgg tgtggttctg gccacatatg cttttaggtg tccacagagt gacgcaggta 83820 aggtatattc atggagctgg aggtcagtca tggaggccaa ggagaagcag gtgtgtgagt 83880 tgccctgtgg gaaagaatgg tgttgaagtg tccagtgaac ctgggcctgt ttctcaagca 83940 tgcatttgat ttctttacac ttctcaggga cagttgccgt gggaggtccg ctgcctgctg 84000 tcaaggaaga tggtcgatgc ttctgagaaa caggccctgc gggttcctgg atttggtgtg 84060 gcctggcatc cacggtgcac cccgtgctgg cgggtggccc aggacggtaa gcatttttct 84120 gccccgtgtg ctgagtgatg gtgcctttag aatttctgag acctgtgagc aacagtttct 84180 tggcaggcca ttaatggcat ggcgagttcc attcccaaag tggatggtct gtgccggttg 84240 ttcagtggcg cggctctggc ttccctaggg tgccaaagtt ctttaacgtc atcggcttgc 84300 ccactgtctg gcctgtgggt gtcaaatgtc ccacctcttc aaatgtgctt ggatcgatga 84360 tgagtccccc ataaaaacat tccttggaaa agctgaacaa aatgagtgag aactcatacc 84420 gtcgttctca tcagaactga ggtccagcac gttgcctccc gtggggactg taggagcgag 84480 ggacaacttc cactggttcc cataggttcc accaccgagg acatccacag gccaaagtct 84540 cccatgaaat actcgttagg aacattccct ctgtgtgagg tacatgggtg ggagatttgt 84600 gggggcactg gctgctctgt gatggcgtgg cggccatgga agaggggaga aatgtcgtgg 84660 gcctagggga gtgtgtggct ggtctcagct tggtgagctt tcaggaaggg aggcctggac 84720 ctcatgggtg gcatctccat gcagaggaca aggtctcact tttgctacca aggagagcac 84780 aaggtccagg cctcaggcag accttgttct tgatttctgg ttagctgagg acagggaagt 84840 gccaagggtg atgagggaga gtgtggagca atgggtgcca cggcagatgg ccaatggctc 84900 ttcagccctc ctgccaatgt tggtcacagt gtccccccag cacggatttc tttgcctccc 84960 gaaatgtaag atgcctgtgg tttggtggtg aaggtgtagg cagggtggta ttccagagaa 85020 aaggtgctag agggctctcg tggacatgag tgtgcattgg gctttaattt ggcagtgata 85080 ggctttccat ggatttctct ggtggatgac aggtcagcca gggtgggtct ttgagggcat 85140 gtctctgggt gagtgagtgt gaggatggtg tccatggccc tgggtcactt ctgttgttcc 85200 cagcagagta gggggctcta ctgttgtgca catcttcctg gaaatggtct cttggccttc 85260 gttgtcgggt ggccccacct gctgctgctc tcgtgagcaa atactgctct gtatcattcc 85320 cgctttccat cccaaaagtg tccagagcga atgtgccctg tccctggcct gggactctcc 85380 tttgggctcc agtcatgcat gaggctaccc gtggagatct atgtgcattc tgagcagtgt 85440 gtttgcaatc ccaggggcat tgccacagag agtcttgact tggcatgtct ccatgtgact 85500 gtgtgctggc gatgttccag tgttggactc caaaagtccc taggcgtgat aaagcatttc 85560 agctccctta gctggtttga agtcacagag caggcaggac agccatgcca ctttcaaggg 85620 catacagttg gcacagaaaa attggaaagg attggtggtc gtacatcttg cagctcactt 85680 agtagctgca tgcatgtaga ccgggtggtg ttgatgcagt gttgacttgc tggcattggg 85740 gtgggtggta gcatggtcaa gctggctgag tgatgggata ttgtctcaga ggttggtgca 85800 gggaaactct gtgggtgtgt ctaatgcaag gataatgaca atgtcctgtc tgcctggtct 85860 ttggggggtc aggtggagat gtccttttgg aaaggcagcc attctctttg agtgtccaga 85920 gggcatggtg caggcacatg gattgagtgg agggaaggaa gcgtgtgtct tgaggtcctt 85980 tggctaggtt gggaagacta cctgtggccc tgatgctgtt tcagagtgat gtgctggcca 86040 ttgcaaaggc gccctccagt gctggttgtg gttggttttc catcaggtgc acctcacctg 86100 gtaaaggggc cagagacagt gtctggtcat gacatcagat gctctgtgag gaggagcatg 86160 tgctcgtgcc aggggtgctg gctgttaggc aagggacctt ggacctcttt cctcatggcc 86220 ttgaggtcaa agttcacatc ctattgattg aaggctgggg tcttgagtct ttggtttagt 86280 ggggttggtt ccggtctgga ggctgcagac tatgactgcc cgctggggtg ttgggaaaca 86340 catgtgcatt agggggacac acatccacac agagacacac tcatgcacac atgtgtgcac 86400 agccacagac aaatagatgc agcaatgggt gtgtgcaatc gttaggccac acacacttat 86460 aggtgtccat ggagtgacac aggtaaggta tgaatgggtc tttgaaggca tgtttctggg 86520 cgagtgagtg tcgggatggt gtccatggcc ctgggtcact tctggtcctc ccagcagagt 86580 agtggtatga atatggagat ggaggtcagt catagggtcc aaggagaagc aggggtacga 86640 gttgccccgt gggaaagaat gacattgacg tggtgaccag tggacgtggg cctatttctc 86700 aagcgtgcat ttgatttctt tacacttttc aggggcagtt gccttgagag gcccaccgcc 86760 tgctggcatg acagatggtc agttcttccg agcagtggaa tctccatgga gtcgtggagt 86820 cggtgtggcc tcgcatccac agtgcaccct gtgctggtgg atggctcagg acagtaagca 86880 ttcctctgcc ccgcatgatg agtgagggtg tctttagaat ttctgagtcc cacaaggaag 86940 tttttcagct ggccattaag ggcattgtcg aggcctttaa ggtcatcagc tcgcacactg 87000 cccagcctgc agtgtcaaat gtcctgcctc tttgaatgtg gttggatcga tgatgagtcc 87060 tccaaaaaaa acattccttg gaaaagctga acaaaatgag tgaaaactca taccgtcatt 87120 ctcatcggaa ctgaggtcca gcacattgct tcctctgggg cctttactag tgagggacaa 87180 cttccactag tccctatagg ttctaacacc catggcgttc acaggtgaag gtctcctgtc 87240 atattacaaa cattcccccc actcccctcc caaaaaaagg aacatttcct ctgtgtcagg 87300 tacacaggtc agagagtcat agggtgactg gctgctctgt gatggcatag tggccgtgga 87360 agtggatgga aatgtcgcag gcttagggga gtgtggggct ggcctcggct tggtgagctc 87420 ccaggaaggg ggacctggaa atcgctgcgg gcatccttgc atagaggacc aggtacgtgt 87480 tccagttctg ctttcaagga gagcatgagg cccaggcctc agacagtcct tggtcttgat 87540 ctttggttag ctgaggacag gggagtgcca agggtgatag gggagagcgc acagcaatgg 87600 atgttgtggc agacagctaa agcctttctg tccctccttt cacggtcagt cccagggggc 87660 ccccagcaca gacttttttc acctctcgag ctgtgagatt cctgtggtgt tgtggccaag 87720 cctgggcagg aaggtacccc agagaaaagg ttgtagaggg ctcacgtgga catgcatgcc 87780 atcagtggtc ttgggctgtc atttggtggt gatgggcttt ccagggattt ctctggtgga 87840 tgacaggttg gccattgggg gtcttcaagg gcaggtccta gggagcatga gggtcgggct 87900 gatgcctgtg gtcctgggtc actccattct tcctggcaga gtagtagaag tgtccatctt 87960 cctggaaatg gtctcttggc ccgccattgc caggcggccc cacctgctgc agctcgtgtg 88020 agcaaatact gctctggatc ccatttcccg ctttgaaagc agcttccatc ccaaaggcgt 88080 ccagagggaa tgtgccctgg ccctggccct ggcctgggac tctccgatgg ggtccagtca 88140 cacttggcgt attcatggag gtccttgtgc attccaggca acacatgtgc aataccaggg 88200 gcactgccgt ggagagtctc ttgatttggg atgcctcctc gcctttgtgt gttggcgatg 88260 ttccagtatt ggattctgct acatcctcag ggcaatgaag cgtttcagct cacttagccg 88320 gtttgacatc atagtgcagc caggacagcc gtgccacatt ggcatggcac atagttgact 88380 taggacagtc ggaaagggtt ggtggttcta tgtctcgcag ctcacttcat agctgtttgc 88440 atgtaaacct ggtgatggtg ttgagatggt gttgacttgc tgacgttggg gtggttggta 88500 gtgcagttaa gttggctgca tgatgggatg ttgcctcaga tgtcggtgca gcgaagccct 88560 gtaggtgtgt ccaatgcaag gaaaatgaaa ggtggtgtgt cctgtccacc ttgtctttag 88620 gggttcaggc aggaatgtcc tgttggaaaa ctagccattc cctttgtgtg tcctgaaggc 88680 atggtgcggg catgtgaact gattggagga aggaagtgtg tgtcttgagg tcctttggct 88740 gggttcagaa gactgtctct ggccttgatg ccgtgtgccg tgtttaagac caacgtggtg 88800 gccattgcaa aggtgccttc cagtgcaagt tttggttggt ttggtgtcag gtgtgcctta 88860 cctgggagag cggcgagaga cagtgtctgg tcacgacatt atatgccccg taaggaggac 88920 tgtgtgcttg caccgccagg ggtgctggct gttagtcgag ggacatcagg ccaatgtctg 88980 tctgacccct aggtcaaaat tcgcatccta ctgattgaag gccttgggtc tcgagccttt 89040 tggttgcagg tgtggggatg gtttccaggt ctggaggctg ccaactatga caacccgttg 89100 tgctgttggg aaacatctgt gtgggggaga cacatacaca tagacacact cactctgaca 89160 tacacaccta cacatgcaca ggcgtgcaca gccacaggca gatagatgca gcaatgggtg 89220 tgtgctattg ttgtggtcac atgtgcttcc taggtgtcca cagagtgaca tgggtcaggt 89280 atattcatga agatggaggt ctgtcatgga gcccaaggag aagccggtgt gcaagtttcc 89340 ctgtgggaaa gaatgggatt gaagtggtga ccagtggact tgggcccgtt tctcaagcat 89400 gcatttgatt tctttacact tctcagcagc agttgtcatg agaggtctgc cgcttgctgg 89460 caaggaagat ggtcaattct tctgaccaac agaggctgcc ttgagtcctg atttggtgtg 89520 gcctggcatc tatggtgcac ccaatgctgg tgagtggctc agggtggtaa gcattcctct 89580 gccctgtgtg cagaggtgtc ttttgaattt tgagacctgc aaagagctgt ttctcagcag 89640 gccactaatg gcatggcgag ttccactccc agagctgatt gtctgtgttc attgctcagt 89700 ggtgtggctc tgggttcccc ccaggatgct gaaggtgttt aaggtcatca gctctcccac 89760 tgcccagcct gtggtgtcaa atgttctgcc tcttcgaacg tgcttggatc gatgatgagt 89820 cccccataaa aacattcctt ggaaaagctg aacaaaatga gtgagaactc ataccgtcgt 89880 tctcatcaga actgaggtcc agcacgttgc ctcctctggg gactgtagga gcgagggaca 89940 acttccactg gttcccatgg gttccaccac ccagggcatt tacagatgaa aatctcctat 90000 cacatgcatg tgaggaacat ttcctctgta tgacatagac ggatgggaca gttgtggagg 90060 gattggccac tctgtgatgt tgtggcagcc acggaagcag gtggaagtgt tttgacctag 90120 ggttgtgtat ggctggtctc ggcttggtga gctcccagga agggagaccc gggcctcgca 90180 gcaggtgtct ttatgtagag gaccaggtca cagttcccct gccaaggaga gcatgaggct 90240 caggcctcag atagaccttg gtcttcattt tccactagct gataatggga gttccaaggt 90300 gatggaggag agcacagagc aatgggtgtc accgcagatg gctaaagcct ctttggccct 90360 ccttccagca tcagtcacag gtgccccctg gcatggattt ctttgcatcc ctagccatga 90420 gatgaccatg gtgcagtgac caaggcttgg ccaggatggt accccagaga aaaggtggtg 90480 aagggctcat gtggacatgt gtgtcatcag ctgcattggg ctgtcacttg gtggtgatgg 90540 gcttcccatg gatttctctg gtggatgaca ggtcagccag ggcgggtctt tgagggcatg 90600 tctctgggca agtgagtgtc gggatggtgt ctgtggccct gggtcacttc cggtcttctc 90660 agcagagtag tgggctccac cgttgtgcac acctttctgg aaatggtctc ttggcatgca 90720 ttgttgggtg gccttacctg ctgcaactca tgtgagcaaa taactgctct ggatcctctt 90780 tcccgcttgg aaagcaattt ccattctgaa ggcatccaga gggaatgtgc cctggccctg 90840 gcctgggatt ctccagtggg ttccagtcat gcatggggct atccacggag gtctgtgtgc 90900 attccaggca atgcgtatgc agtcccagcg gcattgccac agagagtctc tcgacttggg 90960 atgactctgc gtgttgacag tgttccagtg ttggattccg ctatgcccta ggcgtggtga 91020 agcatttcag ctcccttaac tggtttgaag tctcagcacg gccaggacag gcatgtcacg 91080 ctgaagggca cacagttggc ttaggaaagc tgaaaaggtt ggtagttcta cggcttgcag 91140 ttcacttagc agaaacgtgc ttgtggaccc cgtggtgttg agacagtgtt gacttatagg 91200 cactgtggta tgtagtagtg aggtcaagtt ggctgtgtga taggatgttg cctcagaggt 91260 cggtgcaggg aagccctgta gatgtgtcca gtgcaagaat gatgacaggc ggtgtgtcct 91320 gtcaaccttg tccttagggg gtcaagtgga gatgtcctct tggaatagca gccattagct 91380 aggatgtcct gagggcacgg tgtgggcatg tggactgagt ggaggggagg aagcccgtgt 91440 cttgagattg tttggctagg ttgggaagac tgcctctggc cttgacactg agtttcaaac 91500 tgaggtgctg gactttgcga tggtgccctc cagtgctggt tgtagttggt tttccaccac 91560 atgtgcctca cctgagaggg cagccagaga gagtgtctgg tcacaacatc agatgccctg 91620 tgaggaggag tgtgtgctca tgccaggctt ggtggctgtt aggcaaggga cctcgggccc 91680 atgtccgcat ggcctcaagg tcaaagttca catcctactg attgaaggcc tgggtcttga 91740 gcttttgggt tgtgaggagg ttcaggtcta gaggctgcag actatgacca ccccttgtgg 91800 tgttgggaaa catatgtgca tgagggagac acacatacac acacacacag acacactctc 91860 tctctcacac acacacacac acacacacac aggcgtgcat agccacaggc aaatagattc 91920 agcaatgggc acatgctgtc gtttcggtca cacacgcttc ctaggtctcc acagagtgac 91980 acgggtcagg tatattcatg gtaatggaag tcaatcatgg aggccaagga aaagtaggtg 92040 tgtgagttgc cctgtaagca agaatggcgt tgaagaggtg accagtggac cttggtctgt 92100 ttcttaagca tgcatgtgat ttctttacac ttctaagggg cagttgccgt gggaggcctg 92160 ccgtctgctg aaaggaagat ggttgatgct tctgagcaat gaaggcccca tggagtcctg 92220 gattcggtgt ggccttgcat ccgtggtgca ccccgtgctg gtggatggct caggacggta 92280 agcattcctc tgccccgcat gatgactgag ggtgtcttta ggatttctga gacccacaag 92340 gagcagttct tcagcaggcc attaagggca tggctgtggt ctttaaagtc attggctcac 92400 ccactgccca gcctgtggtg tcaaatgtcc tgcctcttca aatgtgcttg gatcgatgat 92460 gagtcctcca aaaaaacatt ccttggaaaa gctgaacaaa atgagtgaga actcataccg 92520 tcgttctcat cggaactgag gtccagcaca tttgcctctg ccggggactg taggattgag 92580 ggacaacttc cactagttcc cataggttcc acctcccagg gcatccacag gccaaagtct 92640 cccatcacac acaggttagg aacatttcct ctgtgcgatg tagacgggta agagagtcat 92700 gggcaaattg tctgctttgt tatggtgtgg cagccatgga agagtacaga aattttgcag 92760 gcctcaagga gtgtgtggct ggcctcagct tggtgagctc ccaggaaggg agacccagat 92820 ctcgcggcag atgtcactgc acacaggact gggtccgatt tttttgccaa ggagagcatg 92880 aggtgtgggc ctcaggcaga tctttgtctt gatttctggt tacctgagga caagggagtg 92940 ccaagttgat ggggaagagc aatgggtgtc ccagcagata tccaaaggct ctttggctct 93000 ccttccaggg ttggtcacag ggcctccctg gcagggattt cttggcctcc tgagctgtga 93060 gctgctcgta gtgcaatggc agaggcctgg gcaggaaagt attccagaga aaaggtggta 93120 gagggctcac gtggacatgt gtgtcatcag tggtctgggg ctgtcatttg gcagtgatgg 93180 gcttcacatg gatttctctg gcagatgaca gctcagccag caggggtcat tgagggcagg 93240 tcacagtgaa catgagggtc aggctggcac ccacagccct tggtcacttc tggtcttcac 93300 ggcagagtag tgggctccac tgttgtgcac atcttcctgg aaatggtctc ttggcccgcc 93360 gttgccggat ggccccacct gctgcagctc gtttgagcaa atagtgctct ggatccactt 93420 tcccacttgg aaagcagctt ccatcccgaa ggcatccaga gggaatgtgc cttggctctg 93480 gctctgccct gggcctctcc catgggctct agtcacactt ggggctattc atgaaggtct 93540 gtgtgtattc cagattccag gcaacatatg tgcaatccca atggcattgc cacagagaat 93600 cttttgactt gggatgcctc cgtgccactg tatgatggcg atattcaagt gctggattct 93660 gctccatcct ggggtgatga agcgtttcag ttcccttagc cagtttgaag tcacagtgca 93720 gccaggacag ccatgccaca ttgacgggct tgtggttggc ttaggaaagt tggaaaggat 93780 tggtggttct acagctagca gctcacttag tagccacatg tatctacacc tggtgctggt 93840 gttgaggtgg tgttgacttg caggcattgt tgtgggtggg aatgcggtca agctgactgc 93900 acgatgggac attgcctctg aggtcagtgc agggaagccc tgtgaggtga ccagtgcaag 93960 gacaatgtta ggtggtgtgt cttgtccact cggcttttgg ggcatcaggc gtggacgtcc 94020 tgttggagaa gcagccattc tcttcaggca tcctgagggc acgtgtgcgt acgtggactg 94080 agtggagtgg aggaagctgt ttcttgaggt cgtttggcta ggttgggaag accacctctg 94140 gctttgacgt catgtatcag tgcaacattc tgagcattgg gcaggtgcct tccagcacag 94200 gttttggttg gttttccgcc agatgtgcct tacctgggag tgcagcaaga gacagtgtct 94260 ggtcccgaca tcagaggccc tgtgaggagt agcctgtatt cgcgccaggg gtgtggtggc 94320 tgttacacga gggacatcag gcctatttcc acgtggcctt gagatcagag tgcacatcct 94380 actgattgaa ggtcttgaac ctttgatttg ttggggggat caggtctgga ggctgcagac 94440 tataaccgcc cattgcagtg ggaatctcac acacacacac acacacacac acacacacac 94500 gtgtgcacag ccacaggcaa atactcgcag caatgggcac atgaggttgt tccaggcaca 94560 cacacttcct atgtgtccac agagtgacag aggtaagata cattcatgga gatggagatc 94620 aatcatggag gccaaggaga agcaggcatg caagttgccc cacaggtaag aatgggtttg 94680 aagtgaccag tggacctggg cccatttctc aagcatgcat ttggtttctt tacacttctc 94740 aggggcagtt gccatgggag gcgcaggcct gctggaagga agatggtcga ttctcccaag 94800 caacaaaggc cacgtagagt cctggtttca gtgtggcctg gtatccacag tgcaccccgt 94860 gctggtgggt ggctcaggac ggtaagcatt cctctgccct tcgtgctgag tgagggtgtc 94920 tttgggattc ccaagaccca caatgaacag tttttcagta ggccactaat ggcatgctga 94980 gttcctctcc tagagtggat ggtctgtacc ttttgctcag tggcacagct ctgggttccc 95040 cagggtgccg aacatgttta aggtcatcgg ctcacccact gcccagccta tgatgtcaaa 95100 catcctgcgt ctttgaatgt gcttggatcg atgatgagtc ccccataaaa acattccttg 95160 gaaaagctga acaaaatgag tgagaactca taccgtcgtt ctcatcggaa ctgaggtcca 95220 gcacattgcc tccactttgg cttattgtgg ttcacgggta actgtcatat tacatggtac 95280 ttcactaccc aggcactggc attcaatttt tgtggtcgtt ttgaccatag taaaattctt 95340 tatcataaat gtatttgaga atcatacttg ggtagcccat gaattttttt agtgttactc 95400 ttcttggtgt caagttggtt tcacccttaa tgctaggttt tggatttttg ttgcatgatt 95460 gatttttagc caggttctgg tcaccaatca cagcctttca ccaacattca tggagaaagt 95520 ttccttgttt tttttatatg ttgaggaagt acatatttcc tgaatgtttt tgcttttgtt 95580 ccaatgttgg gctgactggc atgtcatctc ttatcttatc ttgaactgag tagtggtaca 95640 agtttttggc tttcagcatc cagggcacca agtcttttgt acacaaattg caagtattga 95700 agccatggtg ttgattggga tgctctacgc ccatactctt tagtggcatg acgccctccc 95760 agggtacccg gaatccacat gtgcaactct gtatatgtgt ttctgtgaac acagatatgt 95820 gaagccatag ataagcagat ttcatatgta ccacaggagt ctatatgaca tagccttcct 95880 gacctatgta cctgtctgtc tttctgaagc acactcattt cctctgcacc ttcctggtgt 95940 cattggcatg gaaggaaggc ccttgtccaa gaaggatggt cttcgtcttg tgtgatcttt 96000 gagatgccat gaggcccctg gatacaaatg gtgtgggctc ctttggaggc ttttggattt 96060 ctcctgaatg taagtgattt cttctgaaag cattctgatt ttcctcactt gcagggacaa 96120 agactatgtg taggttgatg atgacttaca tatatacgtt tttttttttt ttttggaaag 96180 gtgaacaaaa tgagtgaaaa ctcagtacca tcatcctcat ctaactgagg tccagcacgc 96240 ttctccatca gggcctagat ttagggggcc aacatctgtt tgttatcatg gtgtgcacca 96300 aggcttagga tgtagttgtc tttcagtgaa actgagtagc tgagtatttt gtactcccct 96360 ggctgagaga tacgtttgtt gaacgactta cctgtgagaa ggtggggtag catcctgcca 96420 gtgtgcagga gaaggtaaac ctgcaggtgc cacaggaagg cggtatccag ttgcccacct 96480 ctgcatggct gggtctgtcc ttgattcata cctcttgggt tcgtcacccc ccagaagaag 96540 acaatttatt ccacatgagg agacagcacg gtgccattcc tgagcacttc ttcaactgtc 96600 tttcatctgt ggccggggac atgggacttc ttatggtgtt tgggtagcat caagggctgg 96660 ccatcttgaa gccagtggtg atgctgattt gctctctgga aaggagcctg gagaagctct 96720 ctacagtgaa cttgtacatc tataagtaga attccaaatt tcatggccca agaagggtag 96780 tggctgtggg aaggggagag gtctgtgtgt gcctttacct ggcatcattc catgtgggtc 96840 gtggagtgat gactgtgagg ctctttaaga cattgcaggg tgcccaaggt ccatttcgtg 96900 atatcctcag gatggtttgc ttgggagagc ctgatgtcat ttgcctctga accgctcaga 96960 catcttgatg cagttggggt ttataagagt gtgtcattcc ccacatcgtg gtgacttcta 97020 cttggaaatg tgacctgcga aggtctcctt gcttatatac ctcagcgtct cctgatatta 97080 gggtattttc aaattcctcc taattcttca cagcagtctt ctttgtgaaa tagtcgttgt 97140 gtggtaggac agggctacca tccacaggcc aatgatggat aggtgttgga ctctgatgtt 97200 atgttcacag gcaagtgcct taagatcttg ttttcttagc tgcagcacct tagaaatctt 97260 gtaggattca gaatgcctgg tgctcttctg ggtccctgat ctgtacctgt gtagtgcaca 97320 tggaggttga tttgtgatgt ttctggatgg gaagagtgtg aaggacccaa ggggtaaaaa 97380 tgcctcaagg ccaaaggaaa gttaaccttt gcataggaag aggtttcccc tccaaactct 97440 cctcactgaa gtatcaccat agcctttgtc ttctctgatg gccaggagaa gggtttttga 97500 gttggaggtg ttataagagt ggtgttgaga gtgttcttca tgcttagtgc tctctagttg 97560 atggtgcctt caaaattcat gcctgcctcc taccttcatg tttgggcaaa cccatgcatg 97620 tgtgcagaaa gaaggggagc ccatgggagg tagatacaga ttactccaca acaggacaaa 97680 tgacatgacc cttgccacct atgcacctca ctgcctttct caagcacact gttttgcttc 97740 tgcacttctt aggtggcgtt ggtatggaag gaaggccagt gaccgcaagg gatgactttg 97800 atcttgggag atttttggag atggcaaagt gcttctaaac atgtttggca tggtctcctt 97860 caggctggtg gatacctcag gatggtaagt attggttttc caaaggcacc taatgttcca 97920 tgtttgcagg tatgaggact gtgcatggat caatgatgac ttccatacgt gggttccttg 97980 gaaagttgaa caaaatgagt gaaaacttta tactgtcatc ctcttcaaac tgaggtccag 98040 cacactgctt caacaggggc tagagatgga ggtctacctc tcattcattg acgtgggttg 98100 caccaagggg tctgtccagg cttaggatgg ggttctcttt tggcaagggg tagccccagg 98160 ggagtgggag ctcccatgca caggagattc ctggtgtgaa ggacatctct tagtgaggcc 98220 agggtagcac acacaccatc ttcaagacta ggtgaatgtg caggtgacac aaaggactta 98280 ggctctgtgt cccccagttt gttcttgagt cttagttctt ggttctctca tcatcgggag 98340 gaaggcaggt ccttctcgtt gggaagagag gacaagccta cacttttgcc tcatttttgg 98400 ctcattttta tccttgtgta tgtacataga tttctggtca cctgcatgct tcacatccag 98460 gccagagtgc ctctgttgta ccctctgtgt tatgaagaca tacagttggc ctcctgccct 98520 aagctggggc tgataggcaa cgagtctctg gcttatctca aacctggtgt aggtcaaagg 98580 cttcctcgtt aggggtgcag gtccccgagg cttttatgat caactttgca ggtgtgcacg 98640 ggtgtttaaa gggatgctca acatcagttc tctctagtgg gattatgtac tccatgggct 98700 cccaggatcc agacgtgcat ccctgtgtct atgcagttct gcgtccataa acaggtgaag 98760 ccagagatgg gcagattgca gatgtactgc agggggccag atggcatggc cctcataacc 98820 tctgcacatg tctgcctttc tcaaacatgc ccatgtttca tctgtacctc ccaggtggcg 98880 ttggcatgga aggaaggact gtgtctgtga gggatgatca tcctctcatg tgatccttgg 98940 agatgccagg aagccccttg acacatgtgg catgggctcc ttcagaggct tttggatccg 99000 tcgtgaatgt aagcaagccc ttcccaaagc cctgattttc ctcatttgca gaaacaaaga 99060 ttgtgcctgg atcaatgatg acttccatat atacattcct tggaaagctg aataaaatga 99120 atgaaaactc tataccatca tcctcattga actgaggtcc cagcatgctg ctacattgga 99180 gggcaaggag agggggccaa catctgtttg ttgacatggt ctacaccttg gcttaggatg 99240 tggtcctctt tgggcaaatg caagcgtctg ggctttttgg acttctgtag ctgagagaca 99300 gcttggttga aggaatttcc tctgagaagg tggggtaagc acactgccag cctgcagaac 99360 ttgaagctgc agatggcaca ggaagcagta gccagtagtc tctttgtgca tgactgtgtg 99420 tgtccttgat tcatagcttt ttggtttgtc gcctccccgc ttgcacagga ataccattgc 99480 tttcctttgg ggagagagca tgtcattcct ggacacttgt tcggcttact ttcattctca 99540 gtcgaggatg tgggagttcc catggtactt gggtagcatc aggggcaggc agccatgagg 99600 tgggtggtga gctgatttgc tttctgcaga ggagcccagg gagggtatcc acattgaact 99660 cgtatgtcca taggaggaaa cccaagtcct ttggtccctg cagtgtactg gtggtgggaa 99720 ggggagaggg ctgtgcatgc atgtaccaag cgacattcca tgtgggtcgt ggagcaatga 99780 ctatgagcct cttttgggag ttgtagggtg cccatgctcc atttcatgat gaccttgggg 99840 tgctgggatg ggaatgagat tgcaagtccc tgtgttcctg ccacttcgca gactgacttg 99900 gtttgagaga tctgtgttca ggaacccctg tgggatgctt gtctgtgtta ggcatttgag 99960 cagatattgg cccagggttt ctacccttcc atggttgtac atactgctgg aagggcttgt 100020 tgctccctct gtattgatga ggggaagttt tgcccaggag agcctgatgc catttgcttc 100080 tgaactgctc aggcacttca atgcagttga ggttaagagt gtgtcacttc ccatgtcgtg 100140 gtagcatcta ctcagaaaag tgacccgtca aggtctctgc acttaaattc tccattatct 100200 tatgatgtta ggttattttc aaattcctcc taattcttca caacagtcct ctttgtgaaa 100260 cagtcatgaa gttgtatgag ggctgtcatc cacaggccag tgatggagag ttttgtactc 100320 tgtggccatg ttcacaggca agtggcttaa gacgtatcgt gttctcaggg acagcaccat 100380 agaagccctg taggattcag catgtctgat gcttttctgg ttccctgagc tgcacctgtg 100440 aggaaggcca gaggtggagg ttgatgtgtg attgaatgtg tttctcaatg caaagtgtgt 100500 ggaaggagct tcaaggccga aggaaagttg ttctttgtgc tggaacactt tttccctgca 100560 gctctcccca ttgaaatatc ctcatggctg ttgtcttctc tgatggccaa gagaatggct 100620 tttgagtcag gggtggtgaa agtgtggtat tgagagaatt cttcgcgctt agtgttctct 100680 agtttgatgg tgcccttgaa atgcatgcct gccttatacc ttcatgcctg ggtatatctg 100740 tgcataagtc cccaaagaga ggtcacccat gggaggtaga tatagaatac agcatggcag 100800 gaggaatggc atggcccttg caaactgtgt acctgcctgc ctttctcaag cacacctgtt 100860 tttcctctgc acttcccagg tggcatgggc atgcaaagaa agacagaggc tgcaagggat 100920 aaacttcatc ttgggagatc cctggagatg gcagggaacc catggacaca tgtggcatgg 100980 gctcctttgg gtgccggtgg atcccttcat acggtatgtg ttcatttctc aaaagaccct 101040 aatgttcttc ctttacagga atgaatactg tgcatggacc aatgatgact tccatacatg 101100 cattccttgg aaagctgaac aaaatgagtg ggaactctgt actatcatct tagttgaact 101160 gaggtccacc gggggctata gagggacaac tgtcattttt tttgatgccc gttgcatgaa 101220 gcattcttcc aggcttagga agggattccg tttgggtgaa ggagagtcac aggggagttg 101280 aggctatgtg cacaggactt ctgtctacaa ggctggggta gcacacatgc agtccgtggg 101340 actaggtgaa tgtgcaggtt gctcagggag agttaacctg tagcctgcct ctgggtggcc 101400 aagattgtcc ttgactcctg gctctgggtt cccacaaccc ctggaggaag acaagtaatt 101460 gtgcttggga agagagaaca aggccatact tttgcctttc tttttttcat tcttagtttg 101520 agaacagtgg agttccaatc acctggcata gctttcatgt tgtgttccat gcattgtgag 101580 tacatgcata tggcaggaac acacaggttc ccactgcaag ctgagcctga taggcaagga 101640 gtctctagct taaccccagc ccagtgtacg tcaatggctt cctcattaaa attgcatggc 101700 cctgtagctt ttgtgagtga cattataggt atcgatgtaa gggtgttgag agggatgctc 101760 aatgtcagtg ctctttagtg tgctgatgca ctactacaag ggcacctgag cccttgtcca 101820 tgcatttctg tgtccaaaat caggtaaagc cagagttggg tatcaaccag atacactgca 101880 ggggatcaga ggacatggcc tttgtgtact gcacatctgt cagattttct caagcacacc 101940 cgtgtttcct cttcacctcc cacgtggaag tgatgaattg gccaggacca tgttggtgag 102000 ggacaatcat catctcatgt taacctcaga gaagccagga agctcctgga cacacatggt 102060 gtaggcttcc ttggaggctg ttggatctct cctgaatgta agcaattcct tcccagtgca 102120 ccctgatttt cctcatttgc agaaacaaag attgtgtgtg gatcgatgat gacttccata 102180 tatacattcc ttggaaagct gaacaaaatg agtgaaaact ctataccgtc attctcgtcg 102240 aactgaggtc cagcacatta ctccaacagg ggctagacag agagggccaa cattgattcg 102300 ttgacatggg tggcaccaag gggaccatcc aggcttagga tggggtttct ttgggtgaat 102360 ggtagacaca ggggagtagg atctcccatg cacaggacat accttgtttg aaggacttct 102420 gtgtcctagg gctggataac tcatgtgctg tctggaggac taggtgaatg gcagattgca 102480 tgggaagagt taactggtag cctgcctctg atggccaagt ttgtccttga gtccaagctc 102540 tgggtaccga agtcccccag aggaagacag atccttctgg ttgcggggag agcaaaaggc 102600 tacacctttg ccattagttg gctcatttta tccttagctg aggatgttgg agttgtgttt 102660 acccggcata gcctctgtgc ctatgtgccc atgttgtgta ctgtgcattg tgaggatgta 102720 tatttggcat gaacaggcag gcttcctctc caaactgggg ctgatagaca gcgaggctct 102780 gggttatccc aaaccagata caggtcaatg gcttcctctt taggggtgca gggccttgat 102840 tattttgtga ctggcattgc aggtgttgaa acaagggtat tgagaaggat gctcaacatc 102900 agtgctcttt agcgggatga tgcattctga gggctgccat ccccaagatg agcatacttg 102960 tgtccataaa tttctgggtt cacgaacaag ggaagccaga gacaggcata ttccagataa 103020 accacagggg gaagatagca tggtcctcgt gacctgtgca cccgtctgcc tttctgaagc 103080 atgcttcttt atcctctgca cttcgcaggt agtgttggtg taaaaggcaa acccgtgtca 103140 tgagggatgg tcatcatctt gtgtgatcct tggagatggc aggaagccct ggacatacat 103200 ggtgtggggg ctcctccaga ggctgttggg atcctcctgg atgtaagtga ttccatttca 103260 aagcaccctg agtttcctca tttgcaggga tggagattgt gtgtggatcg atgatgactt 103320 ccatatatac attccttgga aagctgaaca aaatgagtga aaactctata ccgtcatcct 103380 cgtcaaactg aggtccagca cactgctcca tcaggggctc gagagagagg aacaacatcc 103440 atttgttgac acagactgca ccaaggcttg gggtggggtc tttttctggc agaggagagt 103500 agctgggaat tttggacgtt tgtaactaag agacagcttg gttgaaggca gccaggtgtg 103560 tcgtcaattt gtaccttggg tcccttgtcc tccagaggaa gactattgct tccacatggg 103620 gagacagcac aaggtcattc ccagacacct ctttcactca ctttcatcct tgtcaaggga 103680 cgtaggactt cccatggtgt ttggatagca tcaggggcag gcaggcagtc ttcaggagga 103740 tggcgatgct gatttgcttt ctgcagagga gcccagagag ggtatccaca ctgaacttgt 103800 atgtccatag gaggaaaccc aaaccgcatg gtcccagaag ggtcctggtg gttagaaggg 103860 gagaaagctg cacatgcatt taccacacag tcttctgtct gggttgtgga gagatgactg 103920 tgagcctctt ttgggtgtta tagggtgcat acggtttatt ttatgatgat cttgggatgc 103980 tgggatggga atgtaattgc gaatccatgt gttcccgcaa ctccacagac ttgacttggt 104040 ttggcaggtt tgtgttcagg ccctctgtgg aatgcttgtc ttcattaaga atttgagatg 104100 gggctgggca cggtggctca caccttctgg gtgcttgagc tgcacctgtg agaaagaccc 104160 cgaggtggag gctgaattgt gattgagcat gtttcttgaa tgtgaagtgt gttgatggat 104220 gcttgcagta aaaatgcttc aaggctaaag gaaaattgcc ctatgcacag gaagagtttt 104280 ttttttccca aaactctccc cattcaaata tctctatggt ctctgtcttc tctgatggcc 104340 aagggaaggg cttttgagtc ggggcaccaa atgagtggtg tccagagttc ttcacattta 104400 gtgctctgaa gcttgctggt gccctcaaaa tgtatgtgtg cctcaaacct tcatgcatgg 104460 gtactcccat gcacacatcc tgaaatgggt atcccatggg aagtagcgat agggtatccc 104520 acagggggtt gaatggcatg gcccttgtga cctatgtgtt tgcctgcctt tctcaagcac 104580 acccgtgttg cctctgtact tcctaggtgg tgtgggcatg gaaggaaggc cagtggagac 104640 aatggatgat cttgttctta gcagatcact ggatgtggca gggagtccta ggacatgtgt 104700 ggtgtgggct tcttcaggtg ctggtaagta tctattcccc aaaaccccct aatgttactc 104760 ctttgtgggc atgaagactg tgcatggatc gatgatgact ttcatacatg cattccttgg 104820 aaagctgaac aaaatgagtg aaaactctat accgtcatcc tcgtcgaact gaggtccagc 104880 acattgctct tacaggggct ggagtgaggg ccaagtttca tttgttgctg caggttgcac 104940 caaggggttt gttcagttgt aggaggggct ccctttctgc aaggggtagt cacagggttg 105000 tgagatctct cataaatagg aaattgtttt agggacttct ctctgcaagg taacacacac 105060 acaccgtctg taggactatg tgaatgtgaa ggtgacatgg gaagacttag cctgtagcct 105120 gcctctggtg gccatatttg tccttgagtc ttagctctgg gttccatcat tcccttgagg 105180 aaagacaggt gtttgtgctt gggaagagag cacaaagccc cacctttgct gttttttcca 105240 ctcattttca tcattgttca aggacattgc agttccggtt ttatccataa ccagggaagc 105300 cagagacagg cagatagcag atatgccata gggggccaga tgacacggcc ctcatgacct 105360 gtgaatgtgt ctgctttttt gaagcacact cgtatttccg ctgcacttcc caggtggtgt 105420 tggcatgagg aaaggaggta tcttcgaggg acaatcttct tcttgtgcga tccttggaga 105480 tgccatgagg cccctggaca catgtggtgt gggctccttt ggaggctgtt gtatcccttc 105540 tgaatgtaag tgtccacttt ccaaagtcct gattttcctc atttttgggc atgaataatg 105600 tgcatggatc gatgatgact tccatatata cattccttgg aaagctgaac aaaatgagtg 105660 aaaactctat accgtcatcc tcgtcgaact gaggtccagc acactgttca tcaggggcta 105720 gagagagaga caacatccat ttgttgacac aggctgcatc aatgcttggg atgggatcgt 105780 ctttgggtga agtggagtag ctgggcattt tggacttctg tggctgagag acagcttggt 105840 tgaagctctt ccctctgtgt ggctatgtgt gttatcgatt catacccctt ggctcctgca 105900 ctccccagag gaagacagtt actgctgcat ggggacacag cacaatgttg ttcccaggca 105960 cttcttcggc tcacttttat cctaagtcgg ggacatggga gttcctgtgg tgtatgggta 106020 tcatcaaggg caggcagtcg tgaggagggt ggcaatactg atttgctttc tgcagagaag 106080 cccagagagg gtatccacgt tgaattgtat gtccatagga gggggaaacc caagtcccgt 106140 ggcccctgaa gcatcctggc agtggaaggg gagagggccg tgcatgcgtg taccacacag 106200 ccttctgtct gggtcacaga gcgacgactg tgagcctctt tcgggcattg tagggtgccc 106260 atagtccatt tcatgatgac ctcagggtgc tgggatggga atgtaattgt aggtccacgt 106320 gctcctgcat ctctgcagac tgacttggtt tggaaggtct gtgttgagga acctctgtgg 106380 gatacttttc cttggtgcat ttgaggtgtc tgataatgag tgtgtgggtt tctgtatcct 106440 ggtgacttct actcagaaat gtgacccagc aaggtctctg tgcttaaata ccttagtggc 106500 ttgtgatgtt aggttatttt caaattcctc ctaattgtgt gtgacaattc acacaagtct 106560 ttgtgaaatt gtccttgaat tgtatgacag ggctagtgtc tgtaggccag tgatggataa 106620 gttttggact ccacagccat gttcacagcc aagtggctta agatgtatgg tgttcttagt 106680 catagtgcct tggaagccct gtaggattca gcatgtcttg tgctcttctg ggtccccgag 106740 ctgtaccttt gaggaaaacc cagaggtgga ggttgatttg tgattgagca tgtttctcag 106800 tgggaagagt gtcaaaggag cctggggtga aagtacttca ggaccaaagg aaaattgccc 106860 ttcactcaag aagaggcttt ccttgaacct gtccccactg aaatatcctc atgggcttca 106920 tcttctctga tggccaaaag caggactttt gattcagagg tggcaaatga atggtgttga 106980 gagagtttgt tatgcttggt gctctgtagc tggaaggagc cctcaaaatt attgtgtgca 107040 tgatagcttc atgcctgctt acacccatgc acatgtccca gtaagagggg ctgcctgtgg 107100 gagatacata cacgatacac cacagtggga tgaattgtat ggcccttgca atgtgtgtac 107160 ctgcctgctg ttgtcaaaca cacctgtttt tcctctgaac tttccaggtg gcgtgggcat 107220 agaaggaagg ccagtggcca cgagggacaa tcttggtctt gggagatcct ggaaatgata 107280 gggagtccct tgatatgtgt ggcatgggct ccttcaggtg ctagtggatt ccttaggatg 107340 gtaagtgtcc atttctcaga agctccagat attcctcctc tgcagggaca aagactgtgc 107400 ctggatcgat gatgacttcc ttatatacat tccttggaaa gctgaacaaa atgagtgaaa 107460 actctatacc gtcatcctcg tcgaactgag gtccagcaca ttgctcttac aggggctaga 107520 gagagaggga caaatttcat ttgatgatgc ccattgcacc aaggggttct gtccaggctt 107580 aggatggggt ctcgtttggg caaaggagaa tggcagggga gtggaggcta tgtacacagg 107640 agattccttg tttgaaggac tctatttgtg aggccagggt accacacatg ctgtccgcag 107700 gagtaggtga atgtgcagtt gcccaggaag agttagcctg tagcctgcct ctgcatggca 107760 gtttgtcctt gggtcctggc tctggatttc catgttcctt ggaggaggat aggtgatttt 107820 gcttgagaag acagcacagt accatacttt tgttgttttt ctgctcattt catcgtccat 107880 tgaggacaat gaagttgtgg tcagcaggca tagctttcag gccagcgtgc ccatgttgtg 107940 tcccatgcat tgtgagcaca tgcatgtggc atgaacacat aggctgccac tccaagctga 108000 gtctgatagg caatgagact ctggcttatc ctgatcccgg tgtagatcaa agtcttccca 108060 gtaggattgc atggccccga ggctattgtg agctgcattg caggtgtgga agcaagggtg 108120 ttgagaggga tgctcaacat tagtgctctt tagcgagatg atgcactata agggcaccct 108180 gaacccagac gtgcatccct atgtacgtgc atttctgtgt ccataaatag ttgaagccag 108240 acagccagat tccagatgta tcgcaggggg ctggatgaca tggcccttgt cacctgtgta 108300 cctgtctgcc tttctgaagc acgcttgtgt ttcctctaca cctcccaggt agcattggca 108360 tggaaggcag gcccatgttg gtgagggaca attgttatct tgtgtgagcc gcagggatac 108420 caggaaaccc ctggacacaa atggcaaagg cttctttgga agttgttgga tcccttctgc 108480 atgtaagcag ttctttccca gagcgctctg attttcctca tttgcaggga caaacactgt 108540 gcgtggatcg atgatgactt ccatatatac attccttgga aagctgaaca aaatgagtga 108600 aaactctata ccgtcatcct cgtcgaactg aggtccagca cattactcca tcaggggcta 108660 gacagagagg gccaacattc gtttgttgat atgggttgca tcaaggggtc catccaggct 108720 taggatgggg tccctttggg caattggaag tcacagggaa gtgggagctc ccatgcacag 108780 gaaattcctt atttgaagga cttctttctc cctgggcggg ataactcacc tactgtctga 108840 aggactaggt gaatggcagg tggcatggaa agagtttgtg ggtagtctgc ctctggtggc 108900 caagtttgtt cttgagtcca agctctggat tcccagagga agacagatcc cctggttgcg 108960 gggagagcac aagcctacac tattctcact tgttagcttg ttttgtcctt ggcggaggac 109020 gttgtatttc caggcaccca gcatagcctc tttgccgcat ttccatgtca tatcccatat 109080 gttatgagga tttgtgtatt gcatgatcag gcaggcttct gctccaagct ggggctgtca 109140 ggcaaggagt ctctgggtta ttccaaacct gatttaggtc agtggcttcc tctttcagga 109200 ttcatggccc caaggctttt gtgagcacca ttgcaggtgt tgaagcaacg atgttgagag 109260 ggatgcccaa catcagtgct ctttagcagg atggtgcacc tcgagggccc ctggccctgg 109320 gacgagcatc tgcgtgtcca tgcatttctg tgtccatgaa caggcgaggc catagacagg 109380 caaatagcag atgtgtcaca ggggactgga taacatggcc ctcgtgacgt gtgcaacctg 109440 tctgcctttc tgaagcacgc ctgtgtttcc tctgcacttc acaggtggtg ttggcatgaa 109500 aggcaggctt gtatcatgag gaatgattgt catcttgtct gattcttgga gatggcagga 109560 agcccctgga aacacatggt gtggactctt tcacaggctg ttgaaaccct cctgaatgta 109620 agtgatttca ttccaaagca ccctgagttt cctcatttgc agggatgaaa cctgtgtgtg 109680 gatcgatgat gacttccata tatacattcc ttggaaagct gaacaaaatg agtgaaaact 109740 ctatactgtc atcctcgtcg aactgaggtc cagcacatta ctccaacagg ggctagacag 109800 agaaggccaa catccgtttg ttgacatggg ttatatcaag gcgtctgttc aggcttagaa 109860 tgtggtctct tatgggtgat gggggtcaca ggagagtggt ggctcccatg tataggaaat 109920 ttcttgtttg aaggactgtc agtgagggtg ggtaacacat gcattgtctg caggactagg 109980 tgaatgtcca tgtggcctag caagagttag ctggtagccc gcctctggtt gccaatttgt 110040 tcttgagtcc ttgttctggg ttctcaggtc ccacggagga aaacagatct gtgtggttga 110100 gaggtgggta caaggccgca tctttgtcat ttgttggcta actttgtcct tggttgagga 110160 cattagagtt ttggtcacca ggcatagcct atgtgccttt gtgcccgtgt tgtatcccac 110220 gtgttttgag gacatgtatt ttgcacgtaa aggtgagctc ctgctccaag ctggttctga 110280 taccaaagga gtccctggct tatcctaaac tcatggtagg ttaaagcctt cctccttagg 110340 ggttcagggc cgcaaggctt ttgtgagtgg cattgcaggc gttgaagcag tgatgttgag 110400 agggatggtc aatgtcagtg ctctttagca ggatggtgta ctgcaggggc ccccagcccc 110460 gagacgagca tccctgcatc catgcatttc tgcctccatg aacaggggag gccagagaca 110520 ggcagatagt agataaattg caggggactg gatgacatgg ccctcgtgac ctgtgcacct 110580 gtctgtcttt ctgaagcacg cctgtgttaa ctctgcacct cccaggtagc actggcatgg 110640 agggcaggca catgttggtg agggacaatt gttaccttgt gtgagctgcg gagataccag 110700 gaagcccctg gacacaaatg gcaaaggctc cttcggaagt tgttggatcc cttctgaatg 110760 taagcacttc tttcccagag cactctgagt ttcctcattt gcagggacaa atactgtgcg 110820 tggatcgatg atgacttcca catatacatt ccttggaaag ctgaacaaaa tgagtgaaaa 110880 ctctataccg tcatcctcgt cgaactgagg tccagcacat tactccaaca ggggctagac 110940 agagagggcc aacatctgtt ttttgacatg ggttatacca aggcatccgt tcaggcttag 111000 gatggggtct tttatgggtg atgggggtca caggagagtg gtggctccca tgtataggaa 111060 atttcttgtt tgaaggactg tcagtgaggg tgggtaacac atgcattgtc tgcaggacta 111120 ggtgaatgtc catgtggcct agcaagagtt agctggtagc ccgcctctgg ttgccaattt 111180 gttcttgagt ccttgttctg agttcctgga aggaaacaga tttgtctggt tgggaggaga 111240 atacaaggcc acatctttgt cgtttgttgg ctaactttgt ccttggttga ggacattaga 111300 gttttggtca ccaggcatag cctatgtgcc tgtgtgcccg tgttgtatcc catgtgtttg 111360 ggggacatgt acattgcatg aactagtgag ctcctgctca ttgcttctga tacccaagga 111420 gtccctggct tatcctaaac ccaatatagg ttaaagcctt tctcattagg ggcccagggt 111480 cccaaggctt ttgtgagtat cattgtaggt attgaagcaa cgatgttgag aaggatgctg 111540 aacatgctct ttagtgggat gacgtactct gaaggctcct gacccccaga tgagcatcct 111600 tgtgtccgtt aacttctgtg tttatgaaca ggtgaggcca gagacaggca gacagcagat 111660 gtattgcagg gagctggatg acatggccct tggaacctgt gcacatgcct gcctttctga 111720 tgcacgtcca tgttttctct gcacctcccc ggtggtgttg gtataaaaag caggcttaca 111780 tcagcaaggg atgattgtcg tctcatgcga tcctgggaga tggcagaagt cccgggacac 111840 atggagtgtg ggctctttcg gaggctgttg gatccctcct gaatgtaagt gattccttct 111900 taaagcatgc tgattttcct catttgcagg ggcaaggact ggatcgatga tgacttccat 111960 atgtacattc cttggaaagc tgaacaaaat gagtgaaaac tctataccgt catcctcgtc 112020 gaactgaggt ccagcatact gctcatcagg ggctagagag agggacaaca tccgtttgtt 112080 gacaagggct gtgtcaacac ttgggatggg gtcgtctttg ggtgaagtgg agtagctggg 112140 cattttggac ttctgtggct gagagacagc ttagttgaag cacttccctc tgcgcagcta 112200 tgtgtgtcct tgattcaaac tccttggctc ctgcactccc cagaggaaga cagtggcttc 112260 tgcatgggga caccacacaa tgttgttcct gtgcacttct ttggttcact ttcaccctca 112320 tttggggacg tggcagttcc catggtgttt aggtagcatt gagggcaggc agtcctcagg 112380 aggatgttga tgctgatttg ctttctgcag aggagccaga gagggtatcc atgttgaact 112440 tgtatatcca taggaggaaa ccagtcccat ggcccctgaa gggtcctggc agtgggaagg 112500 ggagaggtct gcatgtgcat gtactggaca gcatattcca tgtgggtcat ggagtgatga 112560 ctgtgggcct ctttcgggca ttgtagcagg cccccatttc atttcatgat gacctcgggg 112620 tgctgggaca ggaatgtgat tgcgggtcca cgtgcttctg caactcctca gactgacttg 112680 gtttggaagg tctgtgttca ggaccctctg tgagatgctt gtctccatta ggcatttgag 112740 cttatatcgg cccagggttt ctacctatcg taggttgtgc atactttgcc tctgaaccac 112800 tcaggcacct cgatgcagtc aacgtgcccg attataagag tgtgacttcc catatcctgg 112860 tgatctctac tcggaaacat ggtccaggaa ggtctctgtg cttaaatacc ttagtagctc 112920 gtgatgttag gttattttct aattcctcct aattcttccc aggagtcttc tttgtgaaat 112980 agtcatcttg ttgtaggaca gggctggtat ccacaggcag tgatgcatag gttttgcact 113040 gcgcggccat gttcaaaggc aagtgcctta aaatgtatgg tgttctcagc cacagtgcct 113100 tagaagccat gtgggattca gtgtgtctgg tggtcctctg agctgcacct gtgaggaaga 113160 cgctgaggta gaggttaagt tgttattgaa cgtttttctc aatctgaaaa gtgttcaagc 113220 agcccagggt gaaaagtctt caagactgaa ggaaaattgc cttttgtact ggaagagttt 113280 ttccccaaaa ctctcctcat ttaaatagcc ctgtggcttg tgtcttctct gatgaccaag 113340 aggagggctt ttgagtcagt gatggcaaat gagtggtttt gagagagttc ttacacttag 113400 ggctctgtag cttgatggtg ccttcaaaat taacacgtgc ctgctatctt cattcctggg 113460 tagacccata cacccatccc aaaaggggag tagcctgtgg gaagcacata tgggatatac 113520 cacagtgagt cgagtggaat ggcccttttg acatgtgtac ctgcctcccg ttcttaagca 113580 cacccgtttt tcctctgcac ttcccaggtg ttgtggccat ggaagtaagg ccagtggcta 113640 cgagggacag tcttcatctt gggagatccc tagagagggc agggagcccc ttgacatgtg 113700 gaatgtgatc tctgttgggt gctggtggat cccacaggtt ggtaaatgtc cattttccaa 113760 aagcccctga tgttccttct ttgcagggat aaagactgtg catggatcga tgatgacctc 113820 aatacatgca ttccttggaa agctgaacaa aatgagtgaa aactctatac cgtcgtcctc 113880 gtcaaactga ggtccagcac gtggctccaa ctggagctgg agagagagag acaacttcca 113940 ttggttgatg tgggttgcac taagccatcc atccaggctt aggatggggt ccactttgga 114000 tcaaagggag tcacagggca gtaggtgctc ctgtgcagag gagattcctt gtgtgaagga 114060 cttctctttg tgaggctggg tagcacgcac aatgtctgca ggactgggtg aatgtgcagg 114120 tggcacagaa gagttagccg gtaacccgcc tctgtgtggc caggtttgtc cttgagtgct 114180 ggctctgggt tcccttgttc cccagaggta gatagctcct tgtggttggg aagagagccc 114240 aaggccacat ctttgttgtt ctttggctca ttttttttca tggctgagga ctttttagtg 114300 cccatggtgt tttcgtagca gcagtggaag tcagttgtga ggaggttggt gatgcttatt 114360 ttctttctgg agagtaccct gtagatcggc tccatttatg atttgtgtgt ctccagggag 114420 aaactgaaat cccatggctg gtgatggata ctccaggtgg gaatgagaaa gcgccataca 114480 tgtgttgact tggtacccta agatggggat ggtccgccac atttgcgcgt ctgttttgca 114540 tggtgtgtac tgcacatcac aaatgccatg ttggccttag ggtgctggga atggaatatg 114600 atctgatgtc tacatgggag ggcctttcag cagattgctt ttgtttcctg acagtctttg 114660 ctccatcccc agtcacacgt gtttttctcc agggaacatt ttattggagt atatcaggtc 114720 gatatcagaa aaaaaaatgt tgtggttatc ccaacattaa gtgtggtgat gtaacagcag 114780 tgtggatggt agctcaagtg aacagtggca aaaccaaaat atattggttt acgtaagtga 114840 ccctattctc tcctatgttt gaagtctggt atgcatctct ttctgcaata atctcagtga 114900 tctggaaact ttcaggaggt cttttttaga tattttatgt ccttgtggtt gtactcatac 114960 tccctgcagt gctaagtctg agtcattctg ctatcctagt gctactggaa tttctattgt 115020 tttgggggca ctgtctggtc attgtggata cctctcttgg ggccctttaa taagaagtat 115080 gttagaggtc ggttttgggg cagtgttgac ctcctgccta aggtcaaagg cagttttctt 115140 cctaaatctt attgcaggat tcactgcctg ggggttgtgt gacagggaga gcacaaaatt 115200 agggtatccc atgtggactt gtgtccagta tcaaggcagt gttggataat tttctatatc 115260 cacaaggctc ccactggact ctttatgtcc agcagacatt cacaggccaa cttttctctt 115320 acacaggggg cctcattcct gccatgtgta gcttccatgg aaccatcctt caggttttaa 115380 gtgcaaggat ttctctcaag agtttaattt gtttctttaa gacaccgttt tcttttctat 115440 aaattctgct ttctgtggtt tgtagcacag atgaaattgc caggtcatat tctacatttc 115500 tgcccaatct tggattagtg agcctttgaa atatgttcct tgatcactgg caatggttct 115560 tggaatacca gaacttagtt acaagcattg cagacctaca gaggtttgtt gttattttta 115620 actgcatgaa gcagtgggtt tgtttgtatc ttgtcactca cggctgtcag caaaacttag 115680 gtgttgctaa accagaccac acccatgaat tatagtgcct ctggttcctt ctgtagtagc 115740 ctgtgggaag tagatacagg atgcaccaca agggaatgaa tggcatggcc cttgagacct 115800 gtgtacctgc ttgcctttct caagcacacc tgttttgcct ctaattccta ggtggtctgg 115860 catggaagaa ggccagaggc tgcgatggat catctttgtc ttgggagatt cctggagatg 115920 gtggggagcc cctgggcacg tgcagcatat gtggcgtggg cttcttcagg tgctggtgga 115980 tccctcagga tggtaaatgt ccattttcca aaatcttctg atattccatc tttgtaggta 116040 caaagactgt gcatggatcg atgatgactt ttatacatgc attccttgga aagctgaaca 116100 aaatgagtga aaactctata ccgtcatctt cgttgaactg aggtccagca cattgctcca 116160 acagtgggta gatagagagg gaaaacttcc atttgttgac gcaggttcca ttgaggggtt 116220 tgtccaggct taggatgggg tcccctttgg gcaaagggag tcacagggga gtgcggcctc 116280 ctgtgcacag gagattcctt gtgtgaagga tttacctctg tgagagcagg gtagcacaca 116340 taactatgca ggagcaggtg aatgtgcagg tggcacagga agagttagat ggcagcctgt 116400 ctctgcacag cgaggtttga cttgtcctag ctctgcattc cctcatccct tagaggaagt 116460 tggtttcttc agaagactta aatttgtgga attcagtaga atattatcca cataatgttc 116520 ccagtgaatg ctaggcatat cacccaagat ggccaggcct ctggccataa accatagtaa 116580 atagtagggt gtgcatatat ccattaggga gaacctgaaa ggtccttttt tggccctcca 116640 aggtgaatgc ctgcaaaagc aagcgaagca cgctatctgc ctgcatgagc cccatgtacc 116700 tggcgtggcc tgtgctcctc accgtgtgtc ccacttctgc tgccccttcg ccttgccagg 116760 tggagtctga ctgatttttt gccactgctg ccaccacagg ccacctggag ccccagccag 116820 tttgaggaaa gtggctctgc ttgattttcc ttttttcttt ttttttcctc tttttttctc 116880 catttctgac ttcagcaggt gggacttgga gcttctgctt ctgcagccac agaagactcc 116940 ccagtttgga gggctgtggt tgtgggctcc ctaagcatct ctctgcagag cctctttgtt 117000 ttccatttta cccaccatgt caataattta acacagtggc ggaggagttc atgtctcttc 117060 ctatttgtca ttactcttct aactttcaca gctgtactcg gctactggtc agaataagag 117120 aaaaagcagt ggaaccagga ggatcctaca agaaatattc catttcactt ttgtttgtgc 117180 atataccttt tctgtttaaa tgtggacttc gatttgatat gcttccagtg cagacacaga 117240 tcccatatgt aagagagtat ggagttgcat agaaagaaga cttgtcattt tcctgtactg 117300 ttggtgttct aatctgtctt cgtggttttt gcctcttctg gctttagaag atacaccaac 117360 atggttttgc aacatagcct cttcttattt tagtaaggga ccaaatgtgc atgtcagtaa 117420 caggtgttac cttgaattgg gatcagtgct tgtgtgacta tattcagtga tgtcattttc 117480 tgtcacactc aagtcacaaa atatttaacc acttattttt ttatctctgg aggaataatc 117540 caaaagattg tactggtaaa gccagaacaa tttccaatta tgctaattat ttgtataata 117600 cttagttggc tttatctgtg gtttgttggc ttattttcct gtagcttttc aaggtttttc 117660 tatgagttct gttaaagagt ctgaaaatgg agcgtagaag acatgcttcg atttccagga 117720 tggttgtgtt ttccagagag gcggaggtaa accactggcg cagccctgcc tcccacagat 117780 aattccgggt gcagtgtttc atatctagac ttggacttct atcctaccat acttctttgt 117840 gtgcaggtat ttttggggat aaaatccttg ttttcagctg tatagatgtc ttgcacatac 117900 tcttttgatg gtttgattta tccattgtgt tcagcacgtt tcagtgagca agatatggga 117960 tttaatttcc aatataaaat ccatgactgc tggccgggcg cagtggctta tgcctgtaat 118020 cccagcactt tgggaggcca tggtgggcag atcacgaggt caggagttca agatcatcct 118080 ggccaacatg gcaaaacccc atctctacta aaaatacaaa aattacccat gcgtggtgtt 118140 gtgtgcctat agtcccagtt actcaggagg ctgaggcaag agaatcccct gatcctggga 118200 ggtggaggtt gcagtgagct aagatcatgt cactgtattc cagcctgggc gatagagact 118260 ctggctcaaa aaaaaaaaaa aaaagaatgt tataattatt ttcagcctca tgtctccgtg 118320 tcacacacag gtccatgaag ctgtgttctt tttttttttt tttttttttt tttcagagta 118380 ttttctttct tgtccagatt agctaaattg gattgttcta tgctaaattc acttaatcac 118440 tactctatta tttttgaatt ttttagttct gtttttttca cttggttctt tttttaaaaa 118500 aacttctact acctttctga gacttctact tttttacttt tttcaagaag ctttataatt 118560 acttgctaaa gcatttttac catgactgtt tttaacttct tcagataacc acaacatttg 118620 gttaatcttg aggttggctt ggttaactgt cttttctcat cctgcttatg attttccttc 118680 taattgtgat ttttccggtt cttgatagat gggtgatgtt ttagtttatc ctgcattttt 118740 ttttcctttt taagttagag gaatctgaat ctattcaaat gttttatttt agcaggcatg 118800 tgccctgttt aggtttaatt tgaatgtcct gtcctacttt tgtaggccat gttttcgcag 118860 gcagtcttgc tatcagagct gaggggatgc tgttttgatc acttagttta tctgatgttg 118920 ctgggcctcc aactggtgct gactggtact tcctgagatg gcgaaggttt ttctgtactc 118980 tgagatgccg tgtatctcta tgtaagggga ggagactctg gaccacagga atgaagagaa 119040 catcttaggt caggcagctc aatcatatgc gataacctgg gtcaaccagc cagtagcctc 119100 atgaagtatg ggagggaatt ctccagtgtc agcattcaaa gacatcatga gtttttactt 119160 ctcattttct tttaagtgaa ataatcgcat ggaaattaaa gaataaatat atgaaatata 119220 tgaaacttat atgaaatata agaatgtgag aaggcctaca gcgtggggat ccccaggcta 119280 tttgaacaat gaatgtctgt gttacacatc tttgctcact ttttctctat ttttgtagtt 119340 cattgtggaa ccagcacaga ttttcatacg aaagttattt ctttttaacc tcaaaaagtg 119400 acagaatgga gtgtatcatg aaaaagtctg acatcaaaac ctcaaaatgt gatattggta 119460 agcattttgt cctgagaata ccagcatttc ctcttagggg atcatgacac tgcagtgacc 119520 atgtgaccct ggctgtgcta gtcagcctgg gctgttcatt gactgtgatg ctggtctcca 119580 tgtgattgac tagtgtgggt cagtgcctcc aaaggtgaca gctgtgtgct cagtgtctgc 119640 cacatatctc aggctcaagg tcccttttat aaatgtgcct ggatcgatga tgactttaaa 119700 atggatctca tcggaatctg aacaaaatga gtgaccaaat cacttctgtg ccacttctgt 119760 gagctgaggt ccagcacagg ggccatgcca gacaaacaca tggagggtgt tttgtttggt 119820 cagcactggt actatgaaac ggcctgtgga attagacaac taaccagctc acatacagta 119880 caggaaatta ctggacagtt aacctaccaa tatatggttg ggggtaagac ggagactttt 119940 caaatgcttg gctggtagca tctgtacact acagtgacca gacactggga gccagcacag 120000 gagttatagg atttacagga aattattgtg tgaacccaca agccattcag acatttgtgt 120060 gagcgcccag aatattctgg ttgatggttt gttgcttgat ggcaaagaga tgtcagcatt 120120 caaagacatc atgagttttt acttctcctt ttcttttaag tgaaataatt gcatggaaat 120180 taaagaataa atatcttata tgaaatatat gaaacatatg aaatataaga tatttattta 120240 tatcatataa gatataaata tctcatatga aatcttgtag tatattttca tttgattgcc 120300 aacccagtca ctaggactga aacagttgtt tattttttgt tttcccatca accaagcaag 120360 ctatttaata catgtttcag tgctggtttc aactacatgt tgcagcaaac atttttagaa 120420 gtgatatttc aaattcttgg attttcacat ggatttcatt gtctactttc atatgtcctc 120480 catgtgtgac cactgtatta attaaaagtt gtaataaatg attttgaaag gtatgtgctg 120540 gaggaacttc gggacaaatg ttttagaaaa cattatttcc ataaaatttg gatcaaagat 120600 gtgagcataa ttgttcttgt tatacagatg gtccaatgag tgtctaatgt gaattcttat 120660 aactgtttat aacaaagtag tccatgaagc aaattttgtt tcacaacttt cctaatttcc 120720 cctgtactct gtagattggg tgagatagaa ttccatggaa tttcattgcc aaaccagtga 120780 agtgctaatt ttgacatttg taccagctaa cgtagctgtg aagaaacaca ccaatacact 120840 tctaaggtaa cattcaattt ttagtgaatt tatttttgtg agttattttt attcttttaa 120900 gtaatcaaga atttatgttc acaaggaatt ggttaatact aacagtttca gacattaatg 120960 ttctgatgag ctgaggcatc aatctccttt tgataaaggt tttgttcttt tctctacttt 121020 gaataacata tgaaatgtcc aacagcagtt ctaagttagt gtatattcca tatatgttaa 121080 tagtgaaaca tcctgtctta tgcaaggcta aaaattgtcc gtgtatactt ctcagatttg 121140 tatacatact ctcttcctac aggacagcat agaccaagat ctaggtttca tatggatgaa 121200 tttattcttc cctttgaggc aagacaagaa ggaaagaaag tattgggaat aatgctgccc 121260 tcccatcctc aagggccagt gggaactcta atattggtaa gccttttgtc ctgaaaatac 121320 cagcatttcc tcttagggaa tcataacact ctgctaaccg tgagactctg gctatgctag 121380 tccgccatgg gctggtcatt gactgtgatc ctggtctcca tgattgaata gtgtgggtca 121440 gtgtgtccca gagtgacaga tgtgctcagt gtctgccaca tatctcagac tcaaggtccc 121500 ttttataaat gtgcctggat cgatgatgac tataaaaaaa atggatctca tcggaatctg 121560 aacaaaatga gtgaccaaat catttctgtg ccacttctgt gagctgaggt ccagcactgg 121620 gaccatgcca ggcaaacatg aggagggagt ttacagggac tagggtattg gaaaactaac 121680 ctacccatat atattagagc aaatgaattg ttctcagttc tgtaaatatc cagctgtggt 121740 ttgacatagc aactctcttt gtatttgctt ggcagcattt atagaaacag ctggtagacc 121800 ctggggaacc agggcatagt gagattcatg ggacgttatt tcacctactc ttgagccatt 121860 cacacatttg agctcgcaga attatctggt caatgagcag tctcttgagg gtaatgagat 121920 ggtcaacatc caaatccaaa gatactaatg agattttact tttttttttg agatggagtc 121980 tcattctgtt gcccaggctg gagtgcagtg gcataatctc ggctcactgc aacctccacc 122040 tcctgggttc aagagattct cccgccccag catcctgagt agctgggatt acaggcgccc 122100 gccaccaccc ctggctaatt tttgtgtttg tagtagagat ggagtttcac catattggcc 122160 aagctggtct cgaactccca acctcaggtg atccagccac tgcagcctct caaagtgttg 122220 ggattacagg catgagccgc cgtgcccggc cttacttttt attttcaatt aagtgaaaca 122280 attacatgga aattgaaaaa aaaaaaaggt actctaagta gactactcta gtgtatttta 122340 attttcttgc caattcagcc actaggattg tgtcacttgt ttttttgatt ttagtttttc 122400 gtatcaaaaa gcaaaccact gtttatattt gagtgctggt ttcaactgta tgctgcctca 122460 aataaactta gattatatta caaattcttt tttacataga tttcattggc tatattcata 122520 tatcctcaaa ggtttccatt gtgtttgaag aggtatccta attgtaataa atgcttttga 122580 ttggggatgc cagggaagct ttgagactaa tgtctcagat tttttttaaa aaagtttata 122640 ttctatagtg atcaaagatg taagaataat ttttcttgtc attcattgga tagtccagtg 122700 agtgtctact gtgaattctt atattcactt gtaactaaac attccatttg gcaaatttcg 122760 tttcataact tccctaattt cctctacact ttgtagattg ggtgagatac aattccatgg 122820 aattttacca ctgaaccagt ggagggctaa ttttgtcatt tgtaccagtt aactaacttg 122880 ggaggaaaca gaacaacaca ctcctgaggt agtatccaat ttttagtaaa tttattttta 122940 ttatttttca aactgtcagt gatttggttt ggtgaacaat aggttaatac agacaatgtt 123000 aggaattatt aatctgatgc gctatctgaa gcatcagttt cctttatttt taagattttt 123060 ttcttctctg tagtttggat aatatttaaa acatttccaa gagttataaa ttagtatatt 123120 ttctatgctg attaataatg aaaccttttg tcttatacag atttttaaaa aatggacgtg 123180 tgcgtgcatg tgtatatata taaatatata tatatataaa atctcttctc acaagatgat 123240 gcagactaaa actgcatttt acattttata tggctaagtt tattgtttcc ttgtgttgta 123300 atatgatgga aagtaatggg aataattctg cttcctgtcc ttagggacca gtaggaattt 123360 tcccatgata agcattttgt ccttaaaata ctgacatcct gttaagagat catgacactc 123420 caatgaccat gagaccctgg ctatgctagt cagccagggg gctgaccatt gacagtgatg 123480 ctggtctcca tgattaaata gtgtgggtca gcatgtccca gggtgacaga aagctgtgtg 123540 atcagtgtct gtcacatatc tcagactcag ggttcctttt taaaatgtgc ctggatcgat 123600 gatgacttaa agatttatct aatttaaatc tgaacaaaat gagtgaccaa aacacttctg 123660 taccacttct gtgagctgag gtccagcaca gagaccactc cagtcaaaca tgtgttgcct 123720 ggagttgcaa ctagttggtc agttagaagc aaccacaggg actggggtat ttgaaaacca 123780 cttgagtgca tttattagag gaaacgaatt ttacatttgt gtataaaaat tcaattgtag 123840 ggtaaaatgg aaactctgag agtttggttg gcggcatcta tataccatag aaacagagcc 123900 tgggaagcag aacagtgaga cccaagagaa atgttcctgc ctatacttgg tctgttctca 123960 catttgcctg agctactgat tgatcttttg agggtgatga gatggtcaaa atccaaggat 124020 atgatgagtt tttacttctc attttctttt tttttttatt atactttaag ttttggggta 124080 catatgcaga acgtgcaggt ttgttacatt ggtatacacg tgccatggtg gtttgctgca 124140 cccatcaacc catcatctac attaggtatt tctcctaatg ctatccctcc cctagcccct 124200 gaccccccaa caggccctgg tgtgtgatgt tccctccctg tgtccatgtg ttctcattgt 124260 tcacctccca cttatgagtg agaacatgtg gtgtttggtt ttctgttctt gtgttagttt 124320 gctgaaaatg atggtttcca gtttcgttca tgtccctgca aaggacatga actcatgctt 124380 ttttatggct gcatagtatt ccatggtgta catgtgccac attttcttta tccagtctat 124440 cattgatgga catttgggtt ggttccaagt ctttgctatt gtgaatagtg ccgtaataaa 124500 catatgtgtg catgtgtctt tatagtagca tgatttataa tcctttagat atatacccag 124560 taatgggatt gctgaatcaa atggtatttc cagttctaga tcctagagga attgccacac 124620 tgtcttccac aacggttgaa ctaatttaca ctcccaccaa cagtgtaaaa gtgttcctat 124680 ttctccacat cctctccagc atttgttgtt tcctgacttt ttttaatgat cgccattcta 124740 actggcatga gatggtatct cattgtggtt ttgatacaca tttctgtaat gaccagtgat 124800 gatgagcctt ttttcatgtt tgttggctgc ataaatgtct tcttttgttt tacttctcat 124860 tttcttaaag tgaaacaatt tcatgtggta tcttccaagt atattttaat cagttgccaa 124920 cccagctgct aagattgaac tgtttctttt gttcttctct tgtttttttc tattaattta 124980 gcaaacaatt ttatatatag tttgctatcc ttctccatgg ggcctgcatc ttcagattca 125040 actagccatg gattgaaaat acttgacaaa aaattgtatg gtttcatctg tactgaacat 125100 gtacagtctt tttctctctt tttctctttc tttctttttt ttttttttga gacagagttt 125160 cactctgtca cccaggctgg agtgcagtgg cacgatctca gctcactaca acctctgtcc 125220 cccgggttca agtgattctc ctacctcagc ctcctgaata gctaggatta caggcgccca 125280 ccactgtgcc aggctaattt ttgtgttttt agtagagatg gggtttcacc atgttggccg 125340 ggctggtctc gaactcctga ccttaagtga tctgcctgca tcagcctccc aaagtgctgg 125400 gattacaagc atgagccacc atgcccagcc aagtacagac tttttctttg gttattattc 125460 cctaaaacag tacagtataa caactattta cgcagcattt acattgtatt cagcatcatg 125520 agtaatctag aaatgatttc ctgcatatag gaggatgtac ataggttcta tgccaatagt 125580 gcacagtgct cgctgtgttt aaagaaatat cctaggtata gaataaataa ttttgaagtc 125640 agtgtgttga gaaaacactg acatggatag aaaatattct gtctagaata gaaaaaacaa 125700 tagaatagaa aaagttctat ctgtatcagt ctgatcaaag atgtgagcat aattattctt 125760 gtcatacata tagtctaatg aatgtctaaa gtgaattctt ataactgctt gtaacaaaat 125820 atttcatttg gcaaatgtta tttcacaact ttcctaattg cccatgtact ttgtagattg 125880 gttttcacag aattccatgg actttaactg ctgaaccaat gatgcactga ttttgtcact 125940 tgtaccagct aacgcatctg ggaggcaaca aaacaatact ctcctgaggt aacatcgaat 126000 ttttagtaaa ttcatttttg tgtgttgttt ttattatttt tttaagtaat tgagaatttc 126060 attaggtgtg caaggagtca cttaatacaa atagtattag gcattcaata ctctcatgag 126120 atatctgagc cttcagtttc ttttatttta acattttaca tttttctcaa ctttaacatc 126180 agaaacatcc tataagtgta ataaaattct tatactttac atatagttac atagtaaatc 126240 ctcctgtctt atttaagttt gaaaaatgaa catgtatact tctcattccc atgtatataa 126300 tctcttccca cagaatgagg tggaccaaga aactgggctt catacggatg aatttatttt 126360 tttccctgtg tggagacata aaggaaaagt atagtgaata attccgcctc ccacccacaa 126420 gtccccatgg gaattctcac atgttaaaaa gcattttgtc ctgaaaataa caacaatttt 126480 tcttagggaa tcaggacact ccaatgacag tgagactctg gctatgccag gcagccatgg 126540 gctggtcatt gtgctgctgg tctccatgat tgaatagtgt gggtcattgg tgacagatag 126600 ctatgtgctc agtgtctgcc acatatctca ggttcaaagt cccttttata aatgtgcctg 126660 gatggatgac gacttaaaaa tgaatctcgt tggaatctga gcaaaacgag tgagcaaacc 126720 acttctgtgc agttctgtga actgaggtca agcacaggga ccatgccagg caaacacgtg 126780 cagagagttc agtttggtca gcaactggta ccaaaatggc ctgtggtatt ggaaaacaaa 126840 cccactcaca tagcttacag cacatgaatt gtacagaggt ctgtatgtgt ttgtatatat 126900 ttatatatgt ttgtgtacat atatctttgg ggattatatg gcatttcttt cagtgtttgg 126960 ctggcagtgt ccatactctc atagtaaaca gaattacaca agagtagagg gaacagtagg 127020 aaatggtttt gcctacccta gagtctttta tacatgtttt taggtgctat aatcttgtgt 127080 gtgaggtcag tctctcaggt tcattagatg gacagtgtaa aaggtattat gaggttttac 127140 atattattta tctattaagt aaaagaaata tatggaaatt gaagagtagc ttttatctat 127200 taaagaaaag aatgtatgga aattgaaggg tactttctat ttgtggaaag tcttaacatt 127260 ttaatttcct tattgatctt gtcacagaag ttggaattta agttttgcct gtcactcaaa 127320 gagaagcttt ttagacattt gattaaggga ttctagtaga tgctatagta aacatttcta 127380 attgtaaaat gattaaattt gcaattcata gagttttatg tggatttcat tgcctgatat 127440 tcattatttt tattagtggg tttcatagat gtttaaaggg agatcctagt tttattgtgt 127500 gatactaagg gaggcctttt ggtcttagaa aactgacttt cagtactacc catttccagg 127560 gagtgagcat aatttttatt ctcataccac atgggcaagt gaatatctat ggtttatttc 127620 ttataactcg tcattagtaa ttatgaaagt aagaaagttg acaaatgaaa ctcttttaat 127680 tatgagggtt tcatttgtcg acttcctact tcctcagtgt gctttgtgta ttggaggtaa 127740 tactggaatt gcatggaatt cctactgctg ctccagtaac ctgctgattt tgtcacgtgt 127800 accagattcg ttgtctggca atgagaacaa tacacttcag aggtaatatt gcaattttta 127860 gtaagtgcat ttttcctggg ttcgttctat tattttattt tagcaagtaa gattataatt 127920 ggtttttcaa gcagtctgtt aatccaaatg gtgtgaggcc ctaataatct ggttagtcat 127980 ctgaagtttc tgtgttcttt gtacagtatt tttatacttc ctctgttttc aaataacatt 128040 aggataccct actagcaaaa taatttagta tattttatat acttgtgcat agtaagcctg 128100 ttgtatatgt acactatttg catggttggc aaattacatt tgcacttttt atttttctat 128160 aattttttcc tattttcaaa ggttaatgtg gaccaaaaac tagatttcat ataaaagagt 128220 ttattccttc tacttgaggt gtgacatgaa ggaaagtaat ggaaataatt ctgccctccc 128280 attctcaagg gccaggggga attcaaatat tggtaagcat tttgtcttga aagcaccaac 128340 attcttctta gggggtcatg acactccaat gacaatgaga ccctggctgt gcttgtcagt 128400 catgagactg gtcactggct gtgatgctgg tctttgtaat tgaatactgt gggttggcaa 128460 gtccccaggt gacagaaaga tcagtgttca gtgtctgcca catatctcag gcttaaggtc 128520 ccttttataa gtgtgcctgg atcgatgatg acttaaaaaa atggaaacct tggaaatctg 128580 aacaaaatga gtgaccaaga cacttctgtg agctgaggtc cagcacaggg accataccag 128640 gcaaacccgt ggagggcgtt cagtttggtc aggaactggt accaaaacga acccacttgc 128700 atatgttaga gcagatgaat tgtacagagg cctatatatc ttcgggaatt acatgacaat 128760 gatttaagtg catggctgac agccttcaaa cacctagtaa tcaggctttg gggtaccagc 128820 gtcagaggag tgaacactgt agaaatggct gtgccagcac tcgagtcatt cacactattt 128880 tcgtagacgc cacaacattc ttagtgagta tcagcatgta taggtatatt atgtagtcaa 128940 ttagaaagaa attatcagtc tttgcttgct atttattctt tcactaaaag aaatatgtga 129000 aaattgaaga gtgggttgta ttcatgggat tatcttatta catgctggaa tttgcttcct 129060 aactcagtct caaggattag aacagcattt gtttttcttt ttcctgtcac tcagggagca 129120 attttctaag cattagatga tagattaaat tagatgcttc attaaacatt ttaatgtgaa 129180 ataatgaaat ttctaattct agggatttta gatggatatt gttggctaat aggaatattc 129240 cttcattgag tctttgtata ttttaagaga gattctaatt ttagtaatac tcggggcctt 129300 tggccttcga gaccaaaatc ttggaaacat tgattttctg tacttaccct gttccaagca 129360 acaagcagat tttttagtta tgtggatagt caagtgacta tggctaatta attacaaact 129420 gttgtcagga atcattcagt tgggaaggtt ttgtttcaaa actcctgtaa tgtcccctgt 129480 gccttgcaga acggaagtga ttttggaatt gcatggaatt ctcactgcca tcccaaagaa 129540 atgctgatct tgtcactctt acctgtttca ttccctgggg gcagaacaaa aggacgcact 129600 ccaaaggtaa catccaagtt tgaataaatt tactttttat ggcttatttt gtaatttttt 129660 ctgtagtcaa gtagataatc agttttgtga atgatctgtt aataacagta tgagacatta 129720 attatctggt gaatcatcca aggctttcat tatcctttat ttccaatttt ttttgcgttc 129780 tccttttcag taatatcaaa aacatcctag tagagttatg ttagtatatt tgatattaat 129840 atacataaca aacgctccct tcttgtgcat gtttgacaaa tggacatata tacttaccat 129900 cttcccatat ttgtactgtt ttcacagatc ggcatgaacc aagaactggg tttcatataa 129960 aatattttat tctgtcctct tgagatgtga catgagaaaa gtattgagaa tacttctatc 130020 acctcatctt caagaatccg taggaattct cccatggtaa gcattttgtc ctgaaaatac 130080 tggcattcct cttaggagat cgtgacactc caatgaccat gagaccctgg ccatgctagt 130140 cagccattgg ccagtcattg actgtgatgc cagtctccat aattgaatga atagtgtggg 130200 tcagtgtacc ccaagctgat ggaaagctgt gtgctcagtg tctgtcacat atcccaggct 130260 taaggtacct tttataaatg tacctggatt gacgatgact ttaaaaaaaa aaaatctcat 130320 tgaaatctga aaaaaatgag tgaccaaacc acttctgtga gctgaggtcc agcacacatg 130380 ataggcaaac gtggagggat gtggatggtc agtgcccaca gggactgggg tatttgaaag 130440 ctaatctgcc tgcgtatgtt agaggaaatg aattggacag tcatctataa atatcgtatt 130500 ttttaataaa atggctattc ctttggtgct tggctggtag catccatcca ctggtagtaa 130560 atagaccctg gaaaaccagc acatatgtag tgagacccca tgagacatga ttgtgcctac 130620 ctttgagcca tccataagtt atctgggaca tgacagtctt ttgagtgaga gcagtttact 130680 aaggtcattt agatcatcag ttccaaagat ggtgtggatc ttatcgatta tttttttagg 130740 cagaggtaat atctggaaaa ttaagagtga tttctaacca tgagaatatt ttagtttgtt 130800 taaatttgct tgctaaccca gtaccaagaa ttcagacctt ttttctgtct gtataaagca 130860 atattctaga catttgagtg attcaagtag atgttgtgag atgattacat ttccagtcct 130920 tggaatgtta tgtggatttt attggctaat cttcatattt catcagtgga ttttcctatg 130980 catgttaagg gagatccttg ttaattgatg tctaggtgga ctttacggtt aacctgaaca 131040 ggtcttggaa aaaggacttt aaacattctc ctgttctgtg gaataagtat acttttttct 131100 ggacatacac cttgtcagtg agtatgtatc ataattcctc ataacttctt atcaggaaac 131160 attcgatgta gaagatttct ttctcaactt ctctaattgc ccctgtggtt tgcaggttcc 131220 atgtgatact agagttgcat agatttttaa cctttacgcc aatgaagatc tgaggcaaac 131280 attgcccctt ttttagaagt ttgcatttgt cactgataac tgtaataatt gatcttgttg 131340 aaaagcctgg gaaatgaaga tctgatatgt cacttttacc ggcttcctca actgaaaaag 131400 aatacaatga aacacgctga ggtaacatct aatttttgat atcttttttc ctgggttatt 131460 actgttttaa gtatttagga atttaatggg tgctatatgg agtcagttaa ttcagatact 131520 ataagacctt aatctggtga gtcatctgag gcttctgttt gttcttttcc agaatttttg 131580 tgctttctca gtcttgctga tgatctttct atgggcctga agcgtggaga gtgccagaga 131640 ggctgatcct cagcagtgtg gcagaggaaa gttgggtgcg actaaggggt atgcggtgcc 131700 cacatgccac tgggtcctca gcagtaccac ctggtgagcg tcactcttga gagctgagag 131760 taggtgggaa gcagctcatg gtgagagggt tcagaggccg cctttccctc tctgcgcact 131820 gcccagttct tctagtcaca tgtcccggga cagtaccata cctgtgtgtg tcctgcctgc 131880 attgctgtga ccacttttag tggaatcagg tgcagtgcag ctctgcagct tctgcaaatt 131940 gccacgctcc cactctcaag caggttgagt gctacgagtg atttttagac catttgttta 132000 ttcccttatc atggcttttt gtgacttctt cctccccagt ccgttgggtc acctttaaag 132060 gtaaagtaat cctgaggtgg ttgaatttac ggaaatgcta tgcattattg tgaatgggat 132120 gttcaccggg ccaacatctt cttggaactt tgagcaaact gatagtctgg ttgcacattt 132180 gatttgtctg gcagtaaatg ttggacagta tttggactga tggaagctag agacaaacac 132240 attgactatt gttgaataac actggaaaca tcttaggaga gcagtacatt agctaattta 132300 ataggtacat aaactgaatc ccactgtctt gtgcttgacg gaccagcaga cacatatgct 132360 tgtatcgttc tcatgtttct acatgtttac cctattccca caggtcaaca aagacaaggc 132420 acctagcccc acatgaaact ttattccttt cccttttgag atgtgacatg aaagaaaata 132480 acagaaatga tttttccatc ccatcctcag ggaccagtgg gaatgaattt taccatccca 132540 ccctcaaggg ccaggtcagg tcgctaagca ttttgtcact aaaatattgc ccttttttag 132600 ggattatgta atactctata aggcactgtc tgtgctgggc agcatggagc ctgggtcatt 132660 gctgtgttgg gggcttggtc tccatgactt aatagggtgt atcagtgtgt cccagagaag 132720 tgtactccag agtgctcatt ttctttcatg tttctgaagc aaacagtgcc ccctttttta 132780 gaagtttgca tgtgtcactg ataactttaa taattgatct tgttgaaaaa cctgggaaaa 132840 cagtgagtta aataataact tctctgaaca tgaggtccag cccaattacc tgccctaagc 132900 aaactatatg gaaggagagt tcagtttgtt cagctatgtg gtcccagcaa ggactgtggt 132960 actggaaaac taaccagctt acatgcacta gagaagtaga attggacagt gatctgtagg 133020 tacccagttt ggagatgaaa ttgcaactct gagttcttga ttggcaacat aaatacgttg 133080 atagtaaaca gaccctgggg aatcagcact tgagttgtga aaagcgggaa atagctatgc 133140 ctacactaga gccattcaca cttttgctgg agctgcaata atcttctaag tcatgcttgc 133200 tctcgtgagg gcaatgagat ggtcacaatc caaggagagt tggggttttc acttttcatt 133260 tctctattaa gtgaaaaaag tatatgaaaa ttgaaaaata gatattactt atgtaatctt 133320 cacagtataa tttgcttgcc aagcagtcac tgggatttaa tcagtttctt tgtctttcgt 133380 ttttctcata agctgagaga gtaattttgt gtgcacagaa gtactgtctt cagctacatg 133440 ctgcattaaa cattcctaga tgtgaaatga ttaaatttcc aagtttttaa aatgtggatt 133500 tttctggcca cttttatatc tcttcaatgg gtttctaatg gatttaagga gagagcctag 133560 tcatgatgaa tggtgttgtg ttgggtatgc tgaggaaact ttgagaccaa tgtttcagaa 133620 aaaattattt ctatactgtc atgtttcaag taccgagtat tgttcttgtc atacagatgg 133680 tccagtgaac atctctggtg aattccttac aaccaacctc ttgttactaa atattccatt 133740 aggaatgttt tgtttctcaa ctccctgatt tcccctttat agattggaag tgatattggt 133800 ggaagacaac attttgccgc ttggaattct cacctccaca ccaaagaagt actgtttttg 133860 tcatttgcac cagcttcttt ctccaggaaa gatcaaaacg atgcactgca aggttaacat 133920 ccaattttta atacatgtaa ttccctggat tatttttgtt gtgttattaa ataacttaga 133980 atttttttta caaagtctgt tgaaccaaac actgtaaggc attaataacc tggtgagtta 134040 tttgaggcct tttttcctct cctagaattt ttgcacaatt tatattttga ataatatcag 134100 agacatccta gtagagtaat gaattagtac attttatatg cagatacata gtgaagcctc 134160 ctttcttatg catatttgac aaatggacat gtatatttct catcttccca tatttttact 134220 ccatttccac aggtcatgta gaccaaaatg tgaatgtcat atgaaagagt ttaaacattg 134280 cccttgaaat atgacagaaa gtatcagaaa taattatacc attccatgct cacaggccag 134340 tgggaattct cacagtaagc attttgtcca gagaatattc ttcttaggga actataacat 134400 tccaatgata atggtagtca gccatgtggc tggatcatcg ttcctgtatc ctggtctcta 134460 tgacttagtg tggtgatggt gtcattgtgt ccaagtgtga cagaattgtt agtgtgtagt 134520 gtctgtctcc tatctcaggc tcacagtccc ttttataaac atgcctggat tgatgatggc 134580 ttcagtatct tttggaaatc tggactgagc aatagaattg cttctctcaa attgatttca 134640 agtcatataa aaggccatgt tacacatata ttgttaatct gagggaggct gtgatcattt 134700 aagttgtatt ttataaacac taggaccacc agtaagaaaa caattcaaaa aatattaaaa 134760 gaacaaccaa agaattaaaa tagaataacc gaaaagatct gtttaacaca aaagaaggca 134820 gttaaagatg aacagaggaa ccaataagac atatagaaaa cagataggaa aatgacagac 134880 ataaacccag ccatatgaca attatattaa atttttaaga gattaggaaa ttccgttgtt 134940 ttttaaacat gagcaactat acgctgtcta cagaagagac actttagaac aaaagataca 135000 aatagttgga aagtaaaaag atggaaaaag ctatatccag cgaatccaga agagagcaga 135060 agtggctatt ctgacatcag aaaaaagaga ctttaagata aagtattgct agagaggaag 135120 aaggatagta tttaatgata gaagggttaa tatggaatat gtaacaatta caatcatatc 135180 agcactaaca acagtgccca aaactacata cactgaaatt taacatgatt gaggggatca 135240 ataggcaatt caacaataaa agcttttgtt cataccctct tcttaatcag tgataagtca 135300 attagataga gcatcattga ggttacaaca tacttcagca atgttgtcaa ccaatttgac 135360 ctgagataga tagatagaca gttagacaga cagacagaca gacagagaaa acttcaccca 135420 acaacagaaa tacaaattat tttcaagcat acctggaaca ttctccagga tagagtatat 135480 gttaggctat aaaactgtac tcaataaatt taagattgaa accatgtaga gtatgttgtg 135540 tgaccataga ggaattagaa atcaacacag aaataaattt ggaggtcaca agatatttgg 135600 aaattaacac actttacaga gcccattggt caaaaatata tatattaaac tagaaaggcc 135660 gggggtggtt gcttacacct gtaattccag cactttggga ggcgtaggtg ggcacatcac 135720 ttgaggccag gagttcaaga ccaacctggg caacatggca aaaccccatc tctacaaaaa 135780 aatacaaaaa atgagttgag catggtggtg catgcctgta gtcccagcta ctcaggaggc 135840 tgaggtaggg gaatcacctg agcccagcag gtagaagctg cattgaacca agattgcacc 135900 actgcatacc agcctgggcg acaaagtgag accctgtcta aaaaataaaa ggaatccaga 135960 aaacatcttg catagaattt gatacaacta aagacatgct tagagggata tttatagttt 136020 taaataactg tatcagaaaa aaagggaaga taaataaatg acataagctt ccaccttaag 136080 aaacaagaaa aagactaaac tagaagatga aatccaaagc aagcagaaag aagtaaacaa 136140 tagggattgg agcaaaaatt gatgacataa aaaaccagac aaaatacaga gaaaaatcca 136200 tgaaaccaaa agttgggttt gtgcagagat ttgtgaaatt tacaatcctt tagctagact 136260 gacacagatc attagaatta ggaatgatgg agacaacatc actactgacc ctatagattg 136320 gatcaggaat gtcgctgttt gctgcattgt gctttcttga ggggagagct atgaaggaaa 136380 acaaagttct cattgcactt acaactcaac aacacagcgt tgacattttg attctcactg 136440 gcttcagtgc tcatctctgt gaggtttcca gaagatcccg tagcaatatc actcattcta 136500 aatttatctt tgggctactc tgggaacgct gtctatgggt tagccctgct ctgcaaggag 136560 cagtaagaaa atatatatat attttttgag gctgagtctc gctctatcgc ccagacggga 136620 gtgcagtggc acgatgttgg ctcactgcaa cctccacctc cagggttcaa gcgattctcc 136680 tgcctcagcc tcccaagtag ctgggattac aggcacgtgc caccacacac cgctaatttt 136740 tgtgtttttg tagagacagg gtttcaccat gtgggccagg ctggtctcaa actcccaacc 136800 tcaggtgatc tgccctcctt ggcctcccaa agtgcaggga ttacaggcat gatccactgt 136860 gcctggcaag tatgtttgta gccagtgggg aattatttta actaggcaat aatttgatct 136920 attttgggaa gcctcttgta atcaaatcat atatcaacat taatcacatg gtgagtcctc 136980 catggttttc attcctagag attctaggat gtttgacatt tctctgctta gcttatagca 137040 gaaaggtatt ggatatcaag aatgtttgaa cagtttctcc tttttgggaa tgaagatgaa 137100 attgggctag aatgagatgt gtgattgaga gaatgtccct gaggcctgag cagtgtgtcc 137160 ttttgggtat gggcattgga agcatgtagt gaattcttat aattttatgt tgcctcggca 137220 tccatcttga gtataagttt aactttgtta taccagaagc aaggcttact cacttttgca 137280 cagtttccag ttctacacct ccttctcgtt cctcagtgtg attggtccag atagctgcct 137340 tatccaactg cctcctttgg accacttcat catgggacag cttgatgcaa tctacttgac 137400 aagaccctgg aaccccacac ccctcatgga accagtgtcc acctcccagt cacagtgtga 137460 ccccagggaa ctcttgcctg cttgctttaa acccaccact taaaagtctc cacagaaaac 137520 ctgtttgaat agtacccttg acccaataag ggcattggcc cctgggtgtc tctctctctc 137580 tctctctctc tctctccctc tctctccctc tctctctctc gctccctgac ctctgcgtgt 137640 ggactccagg catgccatat acccctcagg acctgtaagt aatactatct ttatttttat 137700 tttatatctc tcctaatcat tgaaaaggtg ctctctatct tgaagatact atattaaata 137760 aaatgagaac ttgtccctaa cacagttagt gataggctga aacacgctga ttgcactctt 137820 tacccattta gtgatttttc tcaagttact ctacaccatg tattatcaac ataattgata 137880 ttacagaata gaattataag acacttcttt tgccacagaa agttctattg gactcagatt 137940 atctagagct actacatgta tgctattcta tgataaaaga tgtagatgtg ataaaaacat 138000 ttataaaata tctgtcttag aaaagttagc taaaattatt ttgggaaaag tatgtttgaa 138060 aatagaatcg taagctacca cattgtgata aatatttcta aatgtgtcta ttaacttgtc 138120 aggagacaac agagtgaatt aaaacagtag ccttgtatca gtatgttttt attcagaaga 138180 caaatgcacg ttttaactat tatatgttct tggcttaact ttttttgtaa agttaagaca 138240 ttacactttt acatgaatct gtaatttcaa gatatcttaa tggttgacag ggacaggaca 138300 attgaagaaa acctgtaaat acatttggta aaatttatga tggattgttt tgcagatggc 138360 ttcagaggtt attagcacat ctgtttgaga tatgcacagt tttacatttg tcccttaggt 138420 aatcaacagg gctgagatca gtaaatcaca tgtaagccac tgttatgagg ctattctgaa 138480 tagagttaca tcattttatc atatctagac tttctagtta tattggtgct gttgaaaatg 138540 attttgtatt acatgctttc ttccaaatca tagatcaaga tattttattt atgtatgtct 138600 tttaaatgaa gagtggttag gatagtcctg attattgcac ataaatattg cctttcacta 138660 gattattgtt ttgggccaaa ttttagacta ttattttaaa aaagagtacc ttagtttaat 138720 ccaacctttc cagatactta gaaattattg aaatgtatat tttgtgaaga tggtcttatg 138780 aaagttgttg agctagaaac atgtccttca ccagtggaat tcttagaagc tttccttggg 138840 cttcactggg tgctaataga ccatgatcgt attgctctgt atataatggt acaaattttg 138900 ttttataaca ctcagtctta atagaatggg aatattttat cttactaacg tagtcattag 138960 ctggccactc tctgtgtcca ttggacctta tagggtaaag ggagggcagt gcgtatttga 139020 agcctgtgca cgtgacacac aaagggctta gcaacctccg tgttttccca gcacaggata 139080 cccattcttc ctgaatgttt cattgttaaa ttagattgtg tgtgtgtgtg tgtgtgtgtg 139140 tgtgtatttt atattaacat acagatgtat gtattttagt tgcatttttt ttcttaaaat 139200 gttatttttt ctctttttct tttatgtcag gtgatgatag agcccctagg gaagcaaaac 139260 tgtccatgcc cttgccttaa ctttcagata cgataaaaac aacatttata aaatacctgt 139320 cttagaaata ttagctaaaa ttatgttggg gaaagtatgt ttgaaaatag aattgtaagc 139380 taccacattg tgataaatat tactaaattt gtttattgac ttgtcaggaa gcaaaagaat 139440 gaattaaaga aaactccaga gaatgagctg acaacctact ccctggtcag tggctctcca 139500 tgcctacctg tggtctcttg gacacccttg caggtatgtg ggcagggaac tgcatgttta 139560 taggaaacag gcctaggatg gaaggagtta atagatcttg ctcttcttga gtttgatgac 139620 atttgtttcc agttaaatag catgaaaacc catctgagag ccagctgagg gtggatacag 139680 ttctggggag ttaaagacga gtggtcacaa caggtcttcc tcggcaatcc gagcccaaaa 139740 ctgaatctgc ctccataaga ccattatgtg tcagctcttt atttatatga ttgattcatc 139800 cagtggactt ttaatttctt atgtccagat attttttcag ttcttttttt cgtgatacaa 139860 gcaccttgtg gattgcctgt catagaacag gttctcaata aacttttatt gaaaaaagat 139920 gtataagtag attgtcttga gtaattttgt gaataacctg accaactaag cagtagaaga 139980 caaatgattt taaaacagaa agagacataa ctttcagtgg gattcaggtg atctagtcgg 140040 gtctggaaat gcgcaagaga gaaggtccct gatgcagtgt gctgacattg aaatgtgtag 140100 ttgtggacta gatggttatg gtttcagaac tgtgtaagta aggggtagat tccaaattaa 140160 atcaatatta aagagtagca gagaaggaat ttccagattc cagctgcatt gcttgtttca 140220 ttggaagtgg tgtttctctt ttttcttttt tttctttctt tttttttttt ttttttaaac 140280 ctcagaagat gacttcctgg gaactcttct gggagtgaat gttatcagca aattcccaaa 140340 acaacacccc ttagacaaaa agcctcctca cctatgcatt gcctagacca cccactaaag 140400 gtaagatgtt agttaaaata gtccttgctt tctgggagaa gccatgtctt agtagaaatt 140460 gagctgttaa ttttccgaat attgatgatg tttgattaca ttctaattga ttctaagatt 140520 tcataatatg ttaagagatg cagcttttct tatatacctt cgtggctttt ctacatctca 140580 gtacatttac tgttaatatg aaggatttcc ataacttctc tcatctagta aactgaactc 140640 cttcatggct tgatccattg tgatgctaga aaattgttgt acacagaaga cacagtagcc 140700 tctccataac tgttagactg gaagtttgac aaactggtct gaaataactg atcaaatcaa 140760 tgaatgacct agagctttaa gaaaccagat gggaagagac agacatgaaa cccaaggttg 140820 ttgatggcta ttacttttga gcccagcaaa aggagaaaaa gcagcaccaa tatctggcat 140880 cctggacatg aggaagtttt aatgtcattg ttttggcctc atcatggacc caggtgctag 140940 aaatgagatt ttctctgtgt actctgggta tatttgttct agcacaagta gggggaagat 141000 taaagaggaa tttcataccc ccatgactcc ttaggaaatg tgtttctcac ctttgccact 141060 tttccccact gtgtccttgc aggtgatggc cacaaagagg tggatttgtt gagttggtgc 141120 cattccttct actgccagct tcaccaaaac aatgacacag tcttccttcc gcatggagac 141180 tcttctcttt cctgtgttgc agtggatgcc tcctgcagat aagaaatgct taactgagaa 141240 atgctcatgt tgggatatca tcgatgagac tttaatttgg gcatggtgac tgtttccctt 141300 gctgccactt gactcaatcc caggagcctc agtagaggat ataatattac acaagatgct 141360 caaaatggtg gaattgctca gtgctcccat aaatatacat ttataatttt catttgccac 141420 atggtaaact gaaaaataca gactatatta aaaagaaact gcatgatttt ttttcaaaaa 141480 ttcaaagcat atttaaataa tatataaatt aaatgccctc ctctcttcca attctgtccc 141540 tatagttttc ctctattaag tgaactacat gcattctttt agtggataga tgcacacaaa 141600 cacacaagcc attatgggga aggatccacg tgtgtggcca tattgtaaca catttttctg 141660 caaatcacct ctttcattta acagccctta ttcaatggcc tttttctttt tcagtagtac 141720 atacacatct gtgtcatttg ttgaatgacg acatgaatgt tttgtagata aaatataatt 141780 aaatgtttta agcatttctc actcatagat atttatgtta gcaccaaatt tctgtgcaat 141840 gaacctccct atatatcagt aattttgcat ttgtctataa tatcataata aattacttat 141900 cagttgaatt actgggatta agtatgtgca cactttatat ttatattttg aaaattattg 141960 caagattgcc ttcaaaaatg tggttaacaa ctttatcttc aaatggcaat gaatgagatt 142020 gccagctttc ctacagcctc acagacaatg gattttataa atatttaaca tttttgccaa 142080 tgtgatcacc caaactattg tcttaaattg tatctctttt gtttttgagt ttggtcattt 142140 tttcatgttt attagccatc tgtatttttt aatttcttct ttatgtccaa ttttgtgggt 142200 gggaggagga tttagtctct tcctgatttc gaagagctca tttactattt cgggaaataa 142260 gatttggatt gtcaaccatt atagctattt tttacacact tttcaacttt gtttttgtta 142320 taagaatgtg tatgattgtt acatgtccaa gtataaccat gttcgctttt atggcttctg 142380 agtttcatgt catttttgga aagatatata tattgagtcc ataaaaccct tcacctatgt 142440 taaattctaa ttcttttgtg tttttttaat tcaaattctt aaatcatgag aaattttttt 142500 gttttgaaat cttaaagttg ccaagttact tgccattact tgcgattatt tgccaataat 142560 tgcccattta tctgtaccgc catcttgcgc atatgctgta ctctcatctg tgactggctc 142620 catttttgtt ctgtggattt gtgtgtctct tcttctgcct cctgtctcgt gtctgctcgt 142680 tggaagaaat tacagtttag actgcaattt catcaacttt aataaatcaa ttgaggggag 142740 aattggtttt taaaaatatt aagtaagtct tcgtatccaa ggacaaggta tgtcttttct 142800 tattcaataa ttttaattac tgttaatatt ttcactgtgg tgatgggagt ttttctttta 142860 atttattttc ttgttcattt tttgtatcta aagtttttgt tttgttttgt tttgggggta 142920 agttgtcacc ttactgtttc ttgttgcttt tcagattttt tcaaagtata gactaaatcc 142980 ttcacaaata tttaaagttt ttattttccc ccttcatatt gatcctgatt ttagttatgt 143040 tgacaaagtc cacagactgt tactatcaga acacttgaac agttatggaa atattaccta 143100 cccttgattt aatcagagtt taatggtatg cttctttggt ttgactggca cattgtcgct 143160 ggtcatttcc tcccaaagac caccagaaag agctatgatc aagcaaagct gagtttgtta 143220 aacttacctg cagcaaggga aaacaccacc ttgatagggt ttaataatgt ttcaaaatca 143280 agaaatgagg ctttggggtc tgggcaggga actaattaga aatgggcaaa atttgtcatg 143340 caataccttg tgggaaagtg agatgaggtt cttaatgtga gtattgatgg tgaaatcatt 143400 ttctaggtga gctgtttgcc tatataaaga tgttatcaat gacagaagaa ctatttgcct 143460 agataaacaa actgaattta tttattggtt tacagtttta tcttgctggg caggactctg 143520 ctgggggtgg tatcaggtct tattcccaat aggtaagtta tttggatatg ggtggtctta 143580 atcatcaatg tgtaaaatgc tgattttaag tgcgaaatac tttgtctacc atgttaggaa 143640 agtctgccac cttttatctt ttttaaggaa ttttaatcaa aaccaggtgg tagatataat 143700 caaattgttt tgcagaatca attttcctgt tctctttaaa gacttttatc actgtgaatt 143760 aatttactat tattgcaact tcctttaatt ccttgaatga acagacccta ctggttttaa 143820 aaatgtttta ttcttttaat ttactactta attgtgggta ttttaatttg atttggaatt 143880 tttacaagta tacaactaag tgaaattgat ctgtgatttt tcttttttgt gctatttttg 143940 tcatgttttg atatcagata ttctggttgt gttaaaataa ttttgaggat tttcttctta 144000 tactgtgttc tagagtgggt aaaaaagccc tagtctcact atcagtgttt aagtgaacac 144060 atcagtgaca tcatctggac tctcctttgt ttttgctggt ttggagttag gacatctaga 144120 agtttttttc tttttttcct ttttttgtat ggttattgct tgttctttgt tttgtgtcaa 144180 atttaacctg ttttctctta gcaaatcaca gctcatgcag attttcaaac acattagcct 144240 tgttatacaa agtgttcttt catcattcta ttaaatttcc attttcattc cagttatagt 144300 tatttctgct gtgcctttgt taatgaataa gtttaaacag tggatgttta gcatcactag 144360 ccttcccctt ccatctccct taatcaggac cttggtataa tttatcaggt attttttaag 144420 gttctaattt acttatatat attgtttctg tattcttttg tttcttttct taataaattc 144480 ttaaacctgt gtaacacatt catattcact tgttcttggc aatgaaagat ttaccctgct 144540 gtgcatttta taaaacttgt cattatgaac acattgtaaa catacagtgt atgaagagaa 144600 gaaaacagtg aactagcaca tacaaggaac tggaactggt tccatcatta tcagtatttt 144660 gccatattta ctttgtgttt attttaagta ttttcaaata agctagagaa atcttaacgc 144720 ttcttattct cccataaaca tttttacaat tttatttttg aatgtgtatg tatacacatt 144780 cgtatgcttt tatattgttc tataactttc ttttatatca tgtaatatat aaatatttta 144840 atatttctat ctgattatta catatccata gatgtgaagc ttccctattt ttaataactt 144900 atatttttac ataagtaaaa tttacatagt taaatgcatt gatatatagt aattgtataa 144960 ttcaataagt ttcttaaaag taattactat cccattcagg agatagaata tttttattac 145020 ttgagaacct accctattgc ctctttccaa ccaagcacct tctcaaaaaa acaatgttgt 145080 gatttttatg atcatagata agttttgcct gtttggaaat taatataaat ggaatcacac 145140 agtgtgtgtc tggcttcttg cactcatcat aatcatgttg agatttatct gtgctattcc 145200 ctatatcagc agtttaaaaa agtttctata gttgtaatat ttcactaaat ggttatattg 145260 cagtttatct attctcttgt tgacggacac ctgagtagtt tctagttttt agctgttttg 145320 aatgttagca gatctcttat gtaaatacct aaaaattgaa ttgtttgatc ataagacaga 145380 ttttgcttaa cttataggaa actgctagag agtcttctaa agagatggac acttttcgca 145440 ctcccaacca gtgatatgag atttttagtt gctgtccatt tttgccaaca ttggaaattg 145500 tcagtcttat ctattaagtg ggtgtgaggt gatattttgt tgtgacttca atttgaaatt 145560 tgaccactta agaaggcaac cagtttttca tgaagttatc caattgtaaa tcttctttag 145620 taaaatttgt atatttttcc caacttttaa attacaattt tgaagtaatt ttggacttac 145680 gggaaatttg caaaaatagt agagttcctg tgtattctgt acccagcttt ctggatgtta 145740 gcattttata taatcattat tataacatta ttacatacaa tgataattga aatcaggaaa 145800 ttaatataat actgtcaacc aatctgcaga ctatattcag gtttttcaag ttatgctact 145860 aatgtccttt ttatctagtc caggatccaa ttcaagatct cttattttat ctggcatgtt 145920 tcctttgccc tctctcctga ctacaaatct gggagagctc cctcagtctt tctttgtatt 145980 tcatttaatt gacacatttg agaaatacta gaccataatt tggtacacta gtcctcaatt 146040 tggatttgtc cgatattttt attattagat taaggttatg cacttttgac aaaagataac 146100 acagtagtaa cagtgtgccc ttttcagtgg atcatctgga gtacatgaag ttaatgtctt 146160 atttctgctg atactaaata tgacgccttt attaaggtag tgtctgccag gtttatccac 146220 tgcaaagtta ctgttttcct ttctttgtaa ttaatatttt atgagaaaat aatttgagac 146280 tatgcaaata ttttatttca tctaatttca gtattaattg aagattcttg cctgcagcaa 146340 ttatgattat ggtgtttacc tagtaatggt ttctatttcc atgatacttt ctctacttac 146400 tagaatttga ctgtaaggaa gatctgtcct tcttccccat ttatttgtac tcagttgtta 146460 ttttacatca gtatggattt gtggatatct tattttatgg attgttatat attgcaatca 146520 ttgtttgtgt ttgattttca attttttttc tggatttgat cattgggagc tccttaaagt 146580 tggcccctgt gttcttttaa tacaacctca taattttttg accacttctt attttcgggt 146640 atcacaagat attctaggtt tatcttgtat tttccttccc cacgcctgta atcaaccatt 146700 tcctcaaggg gttctagttc ttcatattgg aaaatagtat ttagaaacca agatcttggt 146760 attaagtgta ttaattgcta atggggtttt attgcttcta ggcctagagc tgggagctgt 146820 gtgtccgttt acacacatac acatacacac acacccctat attgtctcta ttcatttatc 146880 tatcttaaat atatatacta atagtatgta gaatactata gatagtatat atctatcttt 146940 attaaaaatc acaagttcat actgttgtgg atcataatcc atcatcatat ggttcatttt 147000 attcttccct cttggcttat ttgtgatttg cttcttcaac agtgagaaac ctacctttca 147060 ttatctacaa tatgttttgt tatttcttca gtgcagtata cacttaaata atttcagaat 147120 tgctaaatta taccccttta aaaatgaaat cactaactac agcacagtat ttaaatatag 147180 ttcttttgtc tttatcctta acagcgttca gtcaacatac tattatttct aaacgtattt 147240 aggttagtta tctttttttt cctatcccct gccatatggt tacattaatc atataatcaa 147300 gcaggttttt ttattgttta tattccattt tgagttccct caccttttgg attattttaa 147360 ctatattttg tatatgtgaa atattactat gtttctaaaa attaggactg tgagaaatac 147420 cactctccca tcatccctgc tacactgatt ctattcctcc cttctttcca ccctaatctc 147480 acccaaccct tagagttaac tagtctaata gtttctggtt tatttttttc tcttgttatt 147540 cttgttcaca agtgggcaga tacatgtata ttttatcata tatcacatgt atattttata 147600 tccccttcct tcttacatga ttagtggcat actatagatt tttttttgtt gcagttttct 147660 ttttccgctt aatatgtcct ggaaatcact tcatgtgtat tcaaagagat attcctcatt 147720 ctgtcatgct tagtgcttaa ctccatggat gcaccacaat ttattcaacc cctctgctct 147780 atgagaattg tttgcaatat gtgtaaagta tcacactaca aatagtttta cattggattg 147840 tttatttgct cttcgtttgg aagtgttctt tgtattactg ggacatacat ttcttgttca 147900 atatatgtgt tgcaaaggtt tctttcatta agtatcttag cctgcctgcc ttcctttcca 147960 tttcctttct ttttcttttc tttcttctcc ttttaatgct gttatgctct aaattttaaa 148020 atggcccgaa tttgccagtg gctcatccct tattgctatt tattcttcct ctccttttct 148080 cccccatctc ttttccttta atttacgtga aattaacata acgtagccat ttagtgcatt 148140 caaaatgttt tgcaactgcc atccttaact agttccaaaa cattttcagc accccaaaga 148200 caacccatac ccattaagca gtcagtccca actctctttc cccatctttt catttttgtt 148260 ttttggagtt tttttgagac aaagtctcac tttgcaccca ggctggagtg caatggcaca 148320 atcatagctc actgcagcct caaattcctg ggcttatgca atacttccac cttagcctcc 148380 cgagcagcta ggactacagg catatgtcac cacaccaggc taatttataa aaaaaatttt 148440 ttagacacag agtcttgcag tgttgcccag gcttcttgtg tctttcgata aacagacatt 148500 gaaaattttt aagtccagta tatcagtttg agtctcttat ttttagtgct tattacttac 148560 tattaaatct ttgcttactc caggtttgca aataatagtt ttctaagttt tcttctagaa 148620 gctttgggac ataagtataa catctatctc aaatcatttt caaatgtagt tgaagttact 148680 tgttttcatc aatctccagt tgttgcagaa ccatttgatc aaaagatttt tctttttcta 148740 ctgaattatc taatgccatt gttgaaaata agttggccat ttacgtatgg atcttttttg 148800 aactctctgt ttttccttct ttatgccatt ctttttcact gaagtttaat agtaaatctt 148860 gagattaagt agtgtgagtc caaaattttg ttatttcaag gctttataga ggaaggagat 148920 ggctacactg ggtcctttgt atgttcactt aaattttaaa attatcttgt caatttccta 148980 aaaagcccaa ccgagaaatt gattttgatt acatcaaaac tatagataaa tttagggggg 149040 attgacatct taacaatgtt gagtctgtag ttctccattt attaggtcgt ctataatttc 149100 tcatagatgt cttttatggt gtttagtata gaagcatacc ttgtagtttt caatatagaa 149160 acattattaa aatttaacat ttaataaact agattaaatt gttaaattta tttgttttgt 149220 tgttttgatg ctattgtaaa tgaatatgtt taaatttcgt tttccagatt tgttactatt 149280 atatgaaaac agtaatattt tcacattgca actgcttttc agttgggttg tcttcttttc 149340 agtcttagga gaaaatatgt aatttcttac cattaagaaa gatactagct gttatttttt 149400 tgtagatgcc cattaccaaa ttgagcaagt tttattctag tgccagtttg ctgttaattt 149460 ttataataat aatgtgataa atttgctgaa tgtttttcta catttattaa tataatcatg 149520 ttttccccct tattctctta ttatgggaga ctgcattggt cagcttttga atgttagccc 149580 aacattgcat tcttgatgta atccaattgg tcactgttat ccttcttgta tatatattac 149640 tgtattcaat ttttctgcta gttatttaag agttattcac ctatgtccgt gatggccatt 149700 atcctgtggt ttccttttta aaaattattt ttgtcagatg ttggcattag gcttcataaa 149760 atgtatttag tatagtgctc tatttgctag tacacttgac ccttgaacaa cagacatgga 149820 gattaggggt tcagactccc ccatagttga caatctgtgg acaattgttt gctctccaga 149880 aacttaacta cgaatagcct actgttgact gaaagcctta cagataacat aactagtcaa 149940 ttaacacata ttttatgtta tatgtattac atactatttt attaacaata aagtgaatga 150000 gagataaaat gttattacga gacataagga agagaaaata tatttactat tcgttacgtg 150060 aaagtagatg atcataaagg tcttcattct catttttatg ttgaataggc tgaggaggag 150120 gaagaagagg aggggttgtt cttactgtat cggggtggca gaagcagtac acttggtgta 150180 actgtatgga aatatagttt ctagcttttt tgatttttca tttctctaaa aatgtttcta 150240 tatggtacag tccttcttcc actgtttact tatttgtagt acccacatca tagaaggagc 150300 catattgtaa agaagtcaaa tgcagactta aataattaga aaccttctgc cagcgtgttt 150360 ttctggcact ccttctgtgt cgtcttcctt atcgtctggt actggttcag aagcacttgt 150420 ctccatcacg tcatcttctg ttaattcctc tagtgtgtta tctattagct cttgaatttc 150480 tccaaggtgt atatcttgaa agccttcact caccaccctt ttttccgtgt tcacgatctc 150540 tttcgtgatt tccttggttg gctgtattgt aaatcctgtc aagtcatgca caacatctgg 150600 acacagtttc ctccagcagg ggagtgtgtt gtgttgggct tgatgctttc acagcttttt 150660 gtgtaacgat ggcatcttca gtgctgtgat ccttccagac tttcatgatg ttctatcagg 150720 gttctcttgc atagtgttag ataatccttt ccataaagta ctgtgtgtaa tgagccttaa 150780 tggtccttat gactccctga tctagaggat gatttagaga tgttatgtct gggggcaaat 150840 agaccacttt gacaccttca gtattgaact catggggtca gggacattgt ccaatcaaaa 150900 aaaaaaactt taaaaggcac tcacttactg caaggtactt cttgacatca gggtcaaaac 150960 atcaatgaaa ccaatacaga aaaaaagact tcttattgtc caggcctttt tgttttacaa 151020 tcaaaagacc ggcagctggt gttttaactt ttcccttcga ggctcaggag ttagctgctt 151080 tatagataag gtcagtcctg atcataaacc caattacatt tgcacaaaac agtagaatta 151140 gcccatccct tcctgcctta aatcctggtg ctcacttctc ttccttacta ataaatgtcc 151200 tttctggcat tttttttttt tcagagtagg gcactttcgt cagtttaaaa acctgttcag 151260 gcagatatcc tttctcctca atgattttct taatggcatc tgggaactgc ttctcctgct 151320 tgactgtttt taagccagac ttctttctaa aattatcaaa ccatcctttg ctggcattaa 151380 attctccaga tttagaacct tcaccttcct tttgcttagg atcatcttgc accctagagg 151440 tatgccttac agcaatcctg tacccgcaga aaagatgcat tttcaataga tagatacttt 151500 gcaaaagtgc aaggttttca cagtgttggt acagctgcaa caatggcttc atgaatttcc 151560 tttttttttt tttttttttt aacaattgtc ctcacactgg atttacttat cttgaaatgg 151620 caagtagccc ctgctggaga cctcaatctg tggtaccttt taagcaatta aacgttttct 151680 tgtaatgtca tgactttcct ctgcttctta ggagtacttc cagtatcacc agtggcactt 151740 catatgggtc ccatggtgtt aaggtttatg gtattacaca agacactatg aaaagtaata 151800 tgagaactgt gaaagctttt gttttgctgc cacatgcaat ttactggagg gagaaactgt 151860 ttcctggcat gatttcgggt cacctggcac tttaagcaga tgcaattgag ctccccactg 151920 tagcaaaagg aggtggctac aaaattatta caataatgct gggtgtacta cagctaattt 151980 tatgcagtta ggatttaata ccacatattt acatttctct caactgcaaa tggcaccatg 152040 taggatctgt gagtatgtgt gagtaggttt tgataaattt taacttttta taatttgtgt 152100 atattttatg gtaataaatg ataaaaatag gctagtatct acatctattt tatgcattca 152160 tgacatacct ttttcttaat ttttttggta tttctggact acgcagttga gttttttcaa 152220 attgtcacaa atttccaaaa atgtatccaa tgtatttatt gaaaaaagtc tgcatataaa 152280 tagatcatat gcagttcaaa cttgtgctgt tcaaaggtca aatttctttg tggaatgttt 152340 gatagaattc attagtgaaa tgatctgggc ctggagtttc cttcgtgata ttttaatgaa 152400 caatttcagt ttatttaata atacaggatt gagagtttct gtttcattta atggcagctt 152460 tagtactgtt tttcaaagag tatagtccat tttatcagat ttgtcaaatt cagtagtata 152520 aagttgctca tgatagttcc ttattaccct tatactgtct gtaagatctc acctttccaa 152580 ttctgatata ggtaatatta ttttttctca ggttggtctt tttttttttt ttttttttta 152640 actatcttgt catttaaaag aatcaatctt tgatttgcta attttctctt tatctgtttt 152700 ttatattatt gatttctttc cttcatctta ccttggtttt aatatgctct tttttttggt 152760 agcttcttaa tcttgagact attaagtctt ctattatgta ccttacttat tttctaatat 152820 aaccattgaa ggctataagc actacattga tagattccac aaactttgat atattgtttt 152880 aattaccatt taattcaatt attttcttcc tttgtgtttt aatttgatct gttattttta 152940 agtggagtat ttaatttcca aatatttggg gcttttctgt gtagtttgtt acaacttctg 153000 ttttagtttt gttttggttc taaaaagtta ctctgatatt tcagctttcc aaatttattg 153060 agacttatgg tctagcatat gatctgtctt gacaaaagtt tcacatgcac aggaatatat 153120 atttaaactc aaggtgtgca gattttgttc agatagatag tgtctagatt ttctagattg 153180 tcagtgaatt tttacaattg ttttataagt tacaaagaga atagtgtaaa aaatttctgc 153240 tgtgattatg attttcttta tctttagttc tctcagttct tcgtgtattt ggaaatatct 153300 tattgtttat acttttatga acatcatgac tgtaataaat tttatctttt cctaatttgg 153360 cctgtcttac cttatgtaat atttctggtc ttgatgtctg cttcgtctga tatctgaata 153420 atattaccag ttttcttggg tttgcagtat gtctggtgta tctttttctg ttctttaaat 153480 ctgtcttcat agtgcttcca ttatagagag catagagatg gatctttttt gtccaattta 153540 accatcagtg acttttaagt ctttggggtc ttaagtccct ttgcattaaa catactaacg 153600 tgactagact tatgcctact atttagctat tgtttttcca tttgtcccct ctagtttgtt 153660 cctctctgcc tgctttgctt cgttcttttg ggttaattga atatttttag tatcctacat 153720 taacttctct gtttacattt cggctccacc tctgggtatt ttgtatgggt tataaaatgt 153780 acccttaatt tatgacaatc tgcttagagt tagtattgta cacttctcat gaagtaaaat 153840 tttatatata tatatatata tatatatata tatatatata tatatatata tatatatgag 153900 ggagtctcaa tctgtcaccc agactggagt gcgggggcat gatctcagct cactgcaaca 153960 ttaggtggaa ctgtattaac tctaaaagga ctgtgataat ttaaagatgt atattataac 154020 catagaataa tcactaaaaa gtacagagaa atatagctaa aaaagcaaca gcagaattaa 154080 aatgtaatag taaaaatact tgattaaaag aatacaggaa agaatgaaga aaagaacaaa 154140 gtaaactgta tagaaaacag atggcaaaat ggtagaccta aacacagtca tattataaat 154200 tactttaacg gtacacttgt ttttcattgc tttaattgat caaatgatag gtaaagtatt 154260 ttaaagtctc tttgtagttt tctttaaatc ttaacatttt gtgcaatgtt tgctttgtga 154320 agattgatgc tatgatattt accaatcatt tagaagagat attgctgggt gttttggtaa 154380 gtttaggtta cttacatatc ttatatgatg aaatcaacat tttttatttg atcaacttaa 154440 tagaggcatc ctgtttgaaa gaagaaaata acagatctac aaaattctga ttcatgtaat 154500 aagtaaccat tatgataata aatgttttta tttattgagt gcatactgaa aagtggtagg 154560 aagattttgt gctgaaatat ttgtaaacct agtaattaaa aaatgttttg gctgggcttg 154620 ttggctcacg cctgtaatcc cagctctttg ggaggccgag gggggtggat cacttgaggt 154680 caggagttcg agttcgagac cagcctggcc aatatggtga aaccctgtct ctactaaaaa 154740 tataaaaatt agccaggcat ggtggtgcac gcctgtagtc ccagctactc gggaggctga 154800 gatgggagag tcgcttgaac ccaggaagca gaggttgccg tgagtcaaga ttacaccatt 154860 gcactccagc ctgggtgtcg cagtgagact ctgcctcaaa aaaaaaaaaa aaaaaaaagc 154920 tgctaattac cccatgctaa atgtgttgta atggtattaa tttgatatat aacatatatg 154980 taacatttta tatatgtgct catatgatga tactgataat acctccctca aattgctctt 155040 ttgagtatta agaaaagttt atatagaaaa accagtttgg aaaggtttgg aacataaggc 155100 tacagtgatt agatgttgag aacagcagca ataatagttg tcattataat atctgattaa 155160 ggcaatattt gcacccaggt ataccttgct tcagaactgt gtgattaacc attatacctt 155220 gaggctattc ataccctacc ttcactttgt tggcataatc tgaagtttta aaccataatc 155280 acatattgca tttgcacaat taaattttaa aatatataca aattacagtc aaattattgc 155340 attcatttca tgactatatt ctgtttccat ccataagtac cgtatggtca acaataacat 155400 gtcaaagaga attttgttgt cacctcgttt cattgtacca tgttcacact gttctttatc 155460 tcttttttcc attggcagta ttgtgttctc aagaagaatt attccagaag cacccctgaa 155520 ataatatatt tccttaattt tggtattatt agcccttctt tgcttttctc tataaattgt 155580 cctgatcagt cacctctctc aattatatac aacacaaagt agcttaaagg agaaaaaaaa 155640 ggagataaat aaccatgttg ggtctggcgt caggcttaat ggagtccagt agtccagaat 155700 ttaaagacac atatgaccgt ttgctccctt atctcttagt tctccatttc ttggtttggc 155760 ttaaatcttc agtcactttt tctttatgtg aatttgcaaa gggatcattt gaagccctag 155820 atgcaattat tacctgcctt gcaatcttgg taggatgtgt cctccttccc tcctccttgt 155880 ccatgtaaaa gttggtgggt gaagagatgg acaaggcttg agtcactaag acattcactg 155940 acctgggaat aactcaggat aggtctggtc atatccccaa tggaggcaat gtaccctaat 156000 gaaaaggtca gggtcactgg tctcattgtc caaggtgtta tctgagctca tggtctcaca 156060 accaagaaaa ttaaggagta tggacacagg gtgaggttgg ttggagcaaa agtttagtaa 156120 gcgaaagaag aaagctctct gcagcagaga ggggagtcca agtggattgc cgtttttaca 156180 gtcattcaaa agctttttta agaaactcct ctcatctctg tagcactttg agtaacttct 156240 cttatcagca aagctgtctg tacaactccc cttatcttat gcagctgtgg gtatgtctct 156300 aggcaagcac aaagcgccgc ttatttttgt ttgtgtaact gagggtttgt tttaggtaag 156360 ccccctcctt tctgtgcagg cttccaggga gcccaccatg tacatatctg aaaagggaag 156420 gaaacttttt gctgggagct tgttaatcat acaaagaata aagggcttcc atgccagact 156480 ttgcctgcct gcttatctat ggcttatctg tgcagctata gcctgagttt cccctggctg 156540 ctctgttttt gcctgtagct gtgatttttt caggcagaca gcttctctga ggactagtct 156600 cttagctgtt tactcaagta atttttcctg tccttttccc tcactatgat taccagctcc 156660 cctaggactt catggtctgg aatgaaatat tccgtgggag tcagggaaag ggagtttgtt 156720 gcaaacatgt ccaggccaga cactttatat aaagtgtcaa agtaaagtac acttacataa 156780 agtgtaagtg ctgccaccac cactagggtg ccaggtactc taacacaagt ctttattccc 156840 atagatgtga gttaacattt ataccaccag ctcacactat caaacaatcc cacgtacccc 156900 aaataaacac tggtgcctgg tgggcagcaa caagccctcc ttcaaggaag gagttcattt 156960 gttggtttat ccagctgctc ccgctttgct tatggaagcg ctccgttttc taggggtctt 157020 agaagctgta gcagtggtag aaagcccctt ttttgtggac tattatgact taggctttta 157080 tcagagcctc agagaattgc tgttgttttg ttggttaggc tttaggtttc caatctgcat 157140 acacaattcc tttgaagcac caggcttcca ggcaatttgg ttgagggaac ttattgggat 157200 atgaaatatt atcaggcacc atttctaatc aatgtaccta agttatgact tcaggtttag 157260 agaaaaaaaa aatttttttc ccttggcttc aggcttcctt ctggaggtga taacctccta 157320 aatggactgt ctttaagggc ctgtggcatg tgccctcctt tcaggaaact agtgtatgcc 157380 tggaggcatt ggtaatggct tctctcatct tactgtggct tgggaagaat atggctattg 157440 cagattttct agtttcatta ccacctgacc ttcaggctcc ttacatgtta taggcagaaa 157500 aggtgcctcc acaaagttgt gggctattct ctgctttcag aaggacagct ggaaatggta 157560 cttaattctt tgtagcagca ccatcatgaa tagctgccca cacccatata catcattatc 157620 ttttttggtg aagactctaa gacttcaggc catgatatcc acaaggctat gttcatgcac 157680 tacttcggta taatctcaaa ataattgcca gctccccagt ggaacgcctg ccttggtcca 157740 tgtggaatgt gggcatatgg taggatttcc ttggaggaac tagaagagga acataaagaa 157800 tgttaggcat ataaattatt gtttcttttt cttcttgttt ctttccactg agttatgtgt 157860 gagcccccac acccacccta ccttcctgtc ctctacctta ctgatgctat tttcaggctg 157920 ttgtagaatt gggtgtgtaa aattaaatta gcctttctcc tcttaatatc tgtaaaatga 157980 acaaatttga caaagaaact acctatctga tatataagaa ggttattagc ctgtaccaca 158040 agtgaaaaag tttcatcctg atatatcaaa atagtaccac ttgaaggaaa acgttggggc 158100 catctgtttc tctcattgta gttagagtac agatttttaa aatatgagcc tcaggcataa 158160 aaatgcagta ttagcaactc aacttgaaga agcagttact agtgtcctgg gtgggcccca 158220 gggaaaatag taccaactgc ctgttatatt taactgcaat taaaaatggc agtgctgggt 158280 atcttctgtc tctgggtcat ctcctaaaga tcctgcagag ggagccatag ctagtgtaga 158340 ggccagccat aactagccat ggcaaagacc acagggaacg ctcttcaaca tgctctgcac 158400 tgatcctcta ccctggtgtg gagaaatgtc agattcatca ctaacaaggt taaaggtgta 158460 aattgaggga aaaaaatgag aaaagttatc tttcacataa gacttcagaa agaaattgcg 158520 tcgtcaggtt tggaactggt ttgtaatttc atccagttat tttcatttta attactgtca 158580 ctgttttctt catccttgat aaactatgag ctctttgaga ttgtcttttt catatcctga 158640 tgtcagagct tcctgtattt tctgatcatg gtatgtgcta agtaaatgca atttttagca 158700 ttttgaatgg tttatcaaat gattgaagga gtgggtaata atatagatta catatacagt 158760 cagccacata tgtgtatgta tgtgtatttg tgtgtgtgtg tgtatatgta tatactgttg 158820 accctccgta tcaatgggtt tcacatttgt ggattcatcc aatcatggat caaaaatatt 158880 ctttaaaaat atggttgcat ctgtactgaa caggcacaaa ctttttttct tatcattatt 158940 ccctaaacaa tgcagtatga caactattta tcatagcatt gacactgcat tagatatgat 159000 aagtaatcta gagattaaag tatataggag gatgcatgtg gatcatatgc aaataataca 159060 ctacatctta tataagggac ttgaacatcc atggagtttg gtatgtggtg ggtgatacct 159120 cctctttgag gaggtgagta tcagagacgc aggtaaatat gatccagagg gcaaagaggc 159180 attgccagcc tcacactggc tgtcaacacc atgctgagtt ccacgaaagc agcgaggaga 159240 gggtggtgtt cttgtttctg gtacaatacc tggcatagag aagatgtcac agcaatgttc 159300 gtctattgaa taagtcacca aaattgtgaa tgactgaata aatgggcaaa gggatttgtt 159360 ccctacttgc tgtgggaagt ttcttgtagt tatgacctcc atgaaagaga gactcgtatc 159420 tggagaaagt tcatagctga aaccatgaga tttaactttt gaagttataa tggatctatt 159480 tttttaacat cataaatgaa gattatgcaa tactgtatgt gcttcaattg acacaacccc 159540 ttcccattca gggctgattt atgttctgta ctgaatgaca ggcacagaag taaatgtgat 159600 aatcctgtcc cgtcgttacc ctttattgtg gtcttgctgt gtcccagcca cacacttcat 159660 actgtatctg tgtcatcatt ctcatataca tctatatagg tacacttcca tagacttagg 159720 cccatttaat ggaggagcaa ctccaacatt tagagatcat gaaaggtacc tcatgacata 159780 tattgaccta gtggcagagc tgcttagttc tacagcctct gagtggaatc ctcacgacag 159840 taaaaacaca agcttggttt ctcacacact ctacctgctt tttctcatcc cctttagtct 159900 ctattccttg ctgagatgtg ttaggcatta aatggttaca gtctacttct gtgtgtagtc 159960 tccaaacact cagaaacctc aaaatttaaa aaaatacaga acaatatgtt attaaataat 160020 cagggacaag ttaaaatggt aaagagaata ggccactttg tgaaatcata tgcagggaag 160080 aaaaaaatac tggagtgaaa acaatataaa aataatacta gatgctgttt cgtagcacca 160140 agtgtgttct agcttctgtg gttgttgctt tatatcattt tatataatct ttacacaaaa 160200 cctacaagca gatattattt cccctatttc aaaaatgaga aaaccaaggc aaatagttgg 160260 taagtagtac atatatatta tcctaactct gaacttctgg attcaaagac catgttctag 160320 gataccattt tgtgtaccag catggaatat gtttttagtt catctattta ctctaaaaat 160380 gtggagcatg tagtgtgaga cagaactgtt ctaggctgtg aggaagtagc tgtgaggatg 160440 gtagtatggg tccctgtaat aatgaaaatg gaatatattg gtatgtacaa gtacatgctc 160500 attaaaggaa attgatgttg gcatagattg cctgggttca aattcccatt taccatgttt 160560 tcctagttgt ctctgtggtg agaggaggtg gaatgtacta gccattacca aaattaagag 160620 agattgttgg aaaaagtctc atttagcaca ataacacatt aaatgtattc aataaatgtt 160680 acttatgact ctttgagaaa acatacgttt aaaaaacatg gcttatgtta cacatactat 160740 atgctggctc ccaaaaataa acatatttcc caagaagtgt ctgttgataa agccaaatat 160800 attcttacta cactaagggg aagcccatct tagcagtgtc tcagcagcat attaggggcg 160860 tgggggacaa aacaggatat ctgggatctt gaagtttcat tttagatggg tctttcagtg 160920 tgggagcttg attaggattg ggtgagggtc atgacacagc attttaagat tgaacgttag 160980 gattttgaga tgagggattc tacagtgtgg aggcataagc tgtggtctga tgctttctgt 161040 tgatgagttg atggtctttg ggaagttccc aggatgaaca aaaatatttg caacttttat 161100 cttcctgggc aagagtctca gaacatctac acttatatca atgaaggtaa aatgataata 161160 atgtccccag cgaagacagg aagccatgtg ggtagataat gtaagttgtg tcatttcatg 161220 gttccatgga taagcagctg tacttaagct gcttatcctg gtggattctg gagatccaca 161280 cttgaaggta tcaacacaga aatatactaa gaggattgtg gtcagagttt gttgtcagct 161340 actgagtgag gagccaggaa catacagctt ttaccaagaa aatctatacc atccacactg 161400 tgatgagccc acaagaccag atatgggact ttagccaaat tacctaattt tattatgtct 161460 ttgattgctt tctggtcctt atctgggata tcagagatcc cagagagatg gcagggatgc 161520 aaattaaaca ttcttccccc aaaaacaaca catttttccc ttataaaatt actatattct 161580 gaaaaatttc atgaacctcc aagtcaagat ggggcattgt ctaacttgcc tgctgtttgc 161640 tatacaatag catggagtca gctccaggct tcccaaccct ttcgaaaagc atgaattgaa 161700 gaggcttaag gagagaagaa agcaacccag aattccctgt gtggttacag tttgggttct 161760 tgcctcaagg cctggttttt ctctttttgg agtaaagtta tctgaagacc tctttttcta 161820 agagaagaaa ctaatgggtc aaaatggacc ctgggggatg tcagggacta cagtgaaggc 161880 agacgttagt tcacccctga aataaatttc tgtccagtgt gcagacagta gccagcagac 161940 ctttgtctcc atcatccaat accagtcttt tcagatctag tcaatgatct atttaaagcc 162000 aaaatatcct tatgagactg tcaaatagta ttgtattttt ttgtatcact cgtcaagaat 162060 agcttagtac ccggcaataa attttatagt actgatatta atagatctca ggtgaaagaa 162120 aagtcatgtg tcttataaga tgggtgaaag ccacctccaa atagatactc tgttctctag 162180 ttgtttttca tgttctattc ctctgtaagt tcagttacaa aagctgactt ccacaaaaag 162240 ttctccagta ttgttttgga accttatttt ctaatatctt gtcatatacg agttgagtcc 162300 caattaatga ttcattatga ggaactggaa acgagaaact gagtggctca ccaaggaaaa 162360 tatgtgcaaa cctaacggac aatttggtta tatgatttaa ccactgcatg cataaattat 162420 aactaggtat tggactcata ctgaggagtg attaaaatgt aactatgcct tataagcaac 162480 ataattaaat gtagctttaa gccagatagg caagaaaata acaaaaggac gcagattaaa 162540 acatgacaat atatggtatt gttctatgag tcttgagtgg aaactctaca tttcatgcag 162600 tcatctactt gggctaaaaa tcatgtgtag tggccatctc cttccaaaga ccatcttact 162660 tctaatgagt tctcattgag gtctcacgtt ctcagtctga ggtctccagg tctcaagatt 162720 tctcagcttg aggtctccag taatgattta agatggttta tgcctctttg attggaagac 162780 atcactctca gtatcaactc cctggaattt tacttctgga tgagtcgtta acagtatccg 162840 atagggtctt ttccatcagg gttcgagggc tttctttctc aggtatctct cctggagata 162900 cctgagacca agcctctgaa tttagaccat gtgagggtca tttagtagag gaaaagctgc 162960 ttgtttacct cttaataaga ctggataaat tgcctgagtt acctgcaata tttggctgtg 163020 atcacttcca ataatgtaga gtctagaagc agaggagata ttcctagact cgtgggttgg 163080 cctgttgcta actcaaaagg gaagatttga tgaaccccag aagttgagct cattgtcatt 163140 aaagcaaaca ttaggccatg tgagtttgag agtctttgat agttttgcta atttgagctt 163200 aaactttttg tttattcttt ctatatttcc tgaagattag agtaatatgg acagcagcgt 163260 ttctgtgtgg actggcagag ctgtacaaag ctctttatca tctcagtaaa atggagatag 163320 tttatacttg tactagagag agagtttggg aacataaaat catgtcaaat tttgctctgg 163380 cagagctgga aatctccaaa caaggcctca atctatcctc caaataagcg aacaattacc 163440 atacatactc aaaacccatt gcagaaggta cttacaaaat ctgtaagtgt tctaaggggc 163500 cctgagattc ttgttcatgc cccatctttg catttttacc aagattatac tggtaacaaa 163560 taagacaccg catgcaacct caataatctt agtgaaattt ctccatcaat gttgattgag 163620 tgcagtagcc aatttttctt tgcttaggta gttaattgca tattaaatgt ttgaaacatc 163680 ccgtttaagg tcctctggcg ctactaagca tctatcctag agtgtgagag attttcctct 163740 tgcaatttac ctgcagattt atattagtaa cggtttgcca actgtggaac caattgttga 163800 cattctataa gaacctgttt gaacccgtca gaaggtttga ttatgaggac caggatctta 163860 gtgagggctc catgctgggg cctcctggta tccccatctt gtattagtgt ttgttttttt 163920 aatagccaca tctttagcaa gctttacaat actcaaaagt tcttttattt gctgaccatt 163980 tttagtagag gctcctgctg agattgagaa ctctgtttgt tcacaaacaa gaccaagaac 164040 tacacacaaa gcatacctgc caccagcact ctcctatctc actcaaactg accagatctg 164100 tagagcgaaa tgagtcctgt catctggcag attttgcctc tggtagtgat tataagggtg 164160 aagtatgtca catcatgtgc catctgatat tcttttgtcc cagtcttaaa gtacagcaca 164220 tcaaagaaca agatgaaaca tggattttta aaaagagatt actaatacat ctatttaggg 164280 catagtttgt aaacaaagac agtacacagc ttcttcttaa ggtaatggaa aaagtagcaa 164340 ttttgaaagt attgccataa gtaataaaga tgtgaggtgc tgatgtgaag taatatttca 164400 taggaattta agcctctatg ctgaaaagta tgtattttca attttgtgta ttttcagtaa 164460 aggttatcca gcaagaggga ctatgaaact taaaggagac cctaacctaa accaagccag 164520 cagaggcttc cagtaattta gctgttgtgg ctattgccac tgggtgaaga tacagacttc 164580 aatgagctgg cccctgagga ttctcctgaa atgcatttag aacaccaaga gcttatcccc 164640 agcactcata tacaaactgg tagagagttc tgtgataatt aggtaggcct aaagtgggag 164700 gtcattggaa ggctaatttt aactcacaaa aatctctttg tgattaggtt cttagggctc 164760 agttttggct actcataaag tgggtaagtc agagagatgg gaaattttgg aaaattttgg 164820 aatgttctgc aataagcatc caaggaaacc caggaatcct cttaatgatc tcttaactac 164880 tagcctgaaa agttttggat agcttataat ctatcaggca taaaggattc atcttcttgg 164940 gataaatcac atcataggta acgaacttaa acaaaattct aacttctctt tggaaattgt 165000 atgacctttc tgagctaaaa caaagtagat aggtagaata agtcttagaa cttgctttgt 165060 ctttagaaca cagtcactgg tcattcatat tatctattga taagagtgga atcacagaaa 165120 tttagggtcc ttgaaatcgt tgtgaaaagt aggaaggtat ctaagtaaat ccaggggata 165180 tagtacaagt atgctgttga ttttgcctag ggtgtaccaa caagtataga gtattttaat 165240 acaaaggcac tataacaaaa aagtagaaca caaatctgcc actataagat atgcagcctc 165300 aaggactcag tggaaataag atggtatttg ggtggggtat gataaacagc gattattcta 165360 tttatggttc tgaagtcctg aaaaaatctg ctatctctgc cactgggttt ttgagcatgg 165420 agtgtaaaag aattataagg gctgttacaa agtttttagc tattatttta gtcctttagt 165480 cctttttaat ctcttggttt tagaagagat tgtgcaagtt gggtagcagt taaggtggat 165540 aaatctgagt cttaaccggg tttatccata agaatgtcaa gcacttcctt gagatcttca 165600 attttggctt gatttagatt caatagtagt cgtgaatcaa tgtccagatt atctatggtt 165660 tctttatgag tgagggagtc agagactcaa ggtctagacc atccagatag catttaattt 165720 acagttccac ccacgtagta acttcctacc tatcatgtga gtgaatatgg tattacagag 165780 aaagaaagag tgtaatttag ttaaagtcca agggtggctg taatgggctg ggatgtgagg 165840 aatatttgat aattattgca gaaacctacc atgtgagtag tttattttca atgaagaggt 165900 tgtgtaatag tgataaggtt taaggttgat gatatttagc acccatatca gttaaaaaaa 165960 tttgcagagt tgtcatttaa tatttagaga aagttttctt tttgacttga aagatgaaat 166020 gttttgtgct tgatacccac cggaagcacc ttgatttgtc acttatttca tgttttgccc 166080 tttgattctg agctaatgca aaacaagtgt tttccaattt ccttactgct tacaggcgtc 166140 tttatcaaga gacttcctta ttccgggttt aatgtctggg ataggaggat gtaattttat 166200 ctctactttg atttttttta atgaaactct ttcaaaatgt ttagtgaggt gctagagatc 166260 tgataatggg aataatattg ctcattgtag ttttttttta catattaaat cctgtttttt 166320 tggcttcagt tcctttctgc aaaatgggga aagatgtgtg tgggctcata tctgcttcaa 166380 ggtctactga gtccttccta agggtattaa agagcctatc ttcaatttct ccaatggaca 166440 catcctttct ttgcttgcag gactggatta taaaacaatc tattttcaca gggaagactt 166500 taggggtagt ctccaaaaga ccttgtccaa tatcttcagt ttttctaaaa ttctttgttt 166560 cctgtaaaat ttgaaactct ttggtttcct gtggtctttt atgtcaccac tgagactgac 166620 ccattttgcc tttttcatgt acttttttgc atctagggtt atcactaaaa tatgaactcc 166680 ttggtataga tttgggagcc ctggattcta acttcctaaa gatgttttat aatcctcgca 166740 agttttcctc tattctgcct gtgctttgaa gagcctttga cggggtctct catctcagag 166800 ttagatggct taaaatcaac cacagatgtt tccctgttgt gagggtagtt taacatgaag 166860 aggtcattga gctttggggt tttctggctg tctgaaagag aagaaaaatt gttcagaggg 166920 agagatgggg gagagaataa taataggata aagtctattt ggtttgagtt atgatttgtt 166980 ggtatctaaa acagagagag agtttttttt ttcttttgcc ctggctaaca aatttcataa 167040 gaaagcagtt ttgaaatctg aattgccttt ggatgtttct cagattaatt aaaaatgtag 167100 actactggat gtttgaaatt ttgatctatt tttattttaa tgtactctta aaaaattttg 167160 ttcatagaaa aacttccccc aaagtggctg ctataattgt aactcatctc tgttgaaatt 167220 atgccattta aataagtata tgaatgtgga ttatcttata aacatatgga agaagaagtc 167280 cagagggcgt ttggaattag aatgagactg gaggcatacc ctgaaagtgt ggtaaaactc 167340 tgaaaaaaat gttgcttatg accccttggg tctctcaacc tgatttctac attgtctaac 167400 tgtagacctg aaggaatttg cagtttcttg ggggtacata agatgttaat aggggatttc 167460 tcttagaacc agactgatga tcaagacaag attgaggaaa attgtcatag gttttgataa 167520 ggacctaggg aaaaatttct ccaaaggaca gcaggctgag aagaaatctt acaaacttct 167580 ccatccctgg ggctgtcttg agggatccac ttacctgggt ctctctcact ctcttcccta 167640 tgaacattcc ttatatatac acatgaagtg gcaaagacaa aggcgaagag tagcatcact 167700 agtaataagg cagtttcacc aaagataaat ttttttcaag tctgatcaaa gtgttcctga 167760 aaagagttcc ttacccttag gagacaaaat aatctcagta tactgggagt tcaatgaaaa 167820 tatactgggg ctcagtccaa tttgatttac ttaatacact gttgcactaa gagatagtcc 167880 tgaccaggaa gctaaaagga tatctgagga ggacaatgaa ttaaggttct gaattaaggt 167940 tcttgtgcct aggctgcaaa gaggtctcaa tctttatgga tcttggtgag atctccaaga 168000 ttgttcaata ctgaattcct agaaatacaa cctgaagaat attttgataa ggcaaagctg 168060 agtttattct taatgtggta agagaaagca atcccctaat agatattaat aacattttgg 168120 acaaggaagg acaaagttag aatatttatg agactttaaa ggctcattta agatgggtct 168180 ttaaatgcca gggcttgatt aggatttggc gaggattatg ataaaagagt ttactgttgg 168240 tggacacagc aaagtaaaga tttggaggtg agggattcaa aaactcttag aatataagct 168300 attgtctgat gttttctact gatgagttaa taagtttcta aggaagttct tgtaataaat 168360 aataaacatt attcacaact tttatttttc tgagcaagaa tttactggaa tagtaaagtg 168420 aaaatagtgc cagtgaaaat agtggaaaat ttaaattgga ggcaattagc catgagagtg 168480 tacatgattt tgtttctcac agtgtcagtt aacatttccc ctctgtgcaa atccttcaat 168540 agtttacaat ttgtttataa taaatgtccg tagaatggcc cacaaaactg gacctggtca 168600 agccactttc tgtcacctct tacctcttag ctactacttg ctgttctgga accactgggc 168660 cagcttctgc accagattct ctcttggccc caagcatttt tccaccgtct ctctctctct 168720 gcttactcct ctgccatcat cagttgtcaa ctaggctaac ctggtacact tctctaagta 168780 tcaatatcac tacaatgttg ctctttaccc ctttccacta ttttcaacac tgatcatgta 168840 atataaaata ttatttaata ttttaaatga ttatccatct ccttgcacta gaatgtaaac 168900 atgctgactg tagagatttt tgtctttgtc ttttactgct ccaacaccaa ttctctgact 168960 ttgaaggcaa taaaaactga ctttaaacct gaaaagaaag agctaaattg ccttccagtt 169020 ctttgaagta aaagtttata cttcaaaaga attgctctgg aaagggagaa actgcaagag 169080 aaatttcaac ttcttgcttc tcaaagagaa aggcaaaatt atataaaatt ttgaggaagg 169140 gtggcattta ggttaaattt ataataaaca gtatagctgg gttagatgga agcaaatgga 169200 gttggtcaga tggggttgat ttgatcaaag ccaagtggaa atgattggaa ggattagaga 169260 gcagaccagt acaagcagtg cttgctgatg tggacattta agtgaaaact cattttgacc 169320 aattttgcag cttcctgagt atggggtgag gatatcctgt tctttagggg ataataagat 169380 tttcagcttc ttttgtacat gtgatgatgc ctttaggcaa gggtgatatt tttcattctc 169440 atgaccaaag cacagaccat aagtctgaac acagaacact atacatggta atctaggtac 169500 tctatttgcc tttgtaggtg attgcaattt tttccttatt taaaatttta agaccataaa 169560 gaatacttga aaagtaactt tttaccaatc atttaaaaaa tactgattaa atgataaaat 169620 cccttaaaaa cacagttaat gcaaaagcca caaaaagaaa tataaaatat agctttacat 169680 ctgttaaaga cactgaacac ataattaaaa tattcccaaa caacaatgct ccatgctgaa 169740 atgttccact agtaaatttt tacaaatatt taagggaaaa atgtataatt ttcattttct 169800 caggatagct gacttctagt aactaaacat gacaaagaac tataaaaatt gaatttacag 169860 aacatggcta ctaggaatat agatccaagt agcctgaaca caataatagt aaatcaaatt 169920 atgtgaattt tttttttttt gagatggagt cttgctctct tgcccatgtt ggagtgcagt 169980 ggcacgatct ctgctcacta caaccttaca acctccacat cccaggttca agtgatcctc 170040 ctgcctcagc cccactagta gctgggatta caggcacttg ccaccatgcc agtttaattt 170100 ttgtattttt agtagagaca gggttttgcc atgctggcca ggctggtctt gaactcccga 170160 cctcaggtga tccacctgcc tcggcctccc aaagtgctgg gattataggc atgagccacc 170220 gcacccagcc aaaatatttt tttaaaaggt cactgcatta taatcatttg gggtttactt 170280 gagaaatgaa gatttttttt ttaaacattc aaaaaatcat tcaacacttc tggtttcagc 170340 tctgatatgt gaggaacttg taagttataa ttactgtcct tataacaaga taaagcagaa 170400 caaattgaaa aaaaaatcaa ttatttcctt taacccatca gagaactgag gcttcaggga 170460 aagttgccac cccaaagtct ggggacaccg attgatacac agctgaaatt tgcttagctg 170520 gaacagaagc cactggagcc acaaattgat aggaacattt aaatagcaat ttagatgaat 170580 agctgggctg aatgtgggct agagtgaaag gaagaaactc ctgggaaccc ccacattttt 170640 gtgggttcta cctccagaac ctcaacaatt tctcatggta aagatttaag aaagatcccc 170700 tcctcctttg gaaagggaga gaagagtaat cattgtgaaa tacacccaga gcattcttca 170760 taacaaagac ctaacctcca ggggaaaaat tttatctgag ccatatctca gtaagggata 170820 aggggaaggg cattcctttc atttcagcct tctctagctt tcctgtttta ccaatcagga 170880 aataaaaaac ccacaattgt caatagagat cagcacttca aggaaataga ttggaagcaa 170940 aagaaggagg gaaaagagta gagaggtcag gtggagttga gggagaggtt ctgccactga 171000 aggaatgttt gtgatggttg taacaccaag acacaggcac acagagactt attcaaaaga 171060 tcatagaaca ctctccccta tgtcttacga ccccaccagc agtgttctgt gtaatagtag 171120 attacagttg aaatagctgt aagacaccaa ttctctcaga ggagtactta gggaagtcca 171180 aagtcaagag cagaaacaaa agacactaga ggaatttggc atttctggtg cctctagtaa 171240 cagcaaacat taaacaaagc ccaattcctc atcagatttc tgtaaatagc attctaaagc 171300 tccatttacc tcagtactta ctaccagata cagttcaaca aaaaattaca atgcacatcc 171360 tatgacaaga aaaaacagtc tgaagagaga aagcaattag cagaaccaga ctcagaacaa 171420 agatgttgga attaataata gagatttaaa ataactatga ttaatatgtt aaggactctt 171480 agacatgcaa aaatagatta tataagcaga gagatggaaa ctcaaaagaa gcaagaggaa 171540 atgctagaaa taaaaaacac tataacataa atgaagaatg ccttcaacag gctcgtaagt 171600 agattcagca cagccgagga aagattcagt gatcttgaag ttaggtcaat agaaattttg 171660 caaactaaaa tgcaaataca gaaaaagaaa agaatgaaga aaatgggaca gaacatccaa 171720 gaactgtgga acaattttta aaggtgcaac atagatgtaa tggggatact aaaagaatgg 171780 agtatagagc ataatatatg tttgaagtaa aaatggccaa gaatttttca aaattaataa 171840 cagacaccaa accacaggcc cagaaatctc agagaacaca aaacagtaaa aatgcaaaaa 171900 aagcaaaaac aaaaacaata aaacctacaa atatcatatt caacctgcgg aaagacaaac 171960 acagaaaaag aaatctttaa agaaggtaga taaaacatcc tcgtcttctc atcaggaaaa 172020 aaaatccgaa agtagtaatg tggtagtcaa ttatggcata tggatgtgtg aaaacaatgg 172080 cagcaatgcc accagagata ggaaaaaaaa tggaaatcct ctgttataag gcacctgcac 172140 taagcgtgaa gtggtatggt gtaatttgaa gatgggttta gattagttaa aaatgtatat 172200 tgtagccagg gtgacatagc aaaacccagt cttaactaac aatacaaaaa ttagccaggt 172260 gtggtggcac acatctgtag ttccagctac ttgggaggct gaggtgggaa agttgcttga 172320 gcccgggagg cagaggttgc agtgagccga gattgcaccc ctgtactcca gcctgggtga 172380 tacagcaaga ccctgtctca aaacaaacaa acaaacagaa atgtatattg taagttctag 172440 ctcaaccagt taaacaaata agaaaagata attgatatgc taagaaagga gataaaatgg 172500 aatcatgtaa catgatcaag taaaagtaga gaacacagta aaatagaggt cttaaagaaa 172560 tagtaatgca atgactagaa agcagttgca aacatggaat atattgatcc aactgtataa 172620 ataatcactt cagatgtgaa ttatctacat tgaaaaacag aaactctcag aatggactaa 172680 gacaagacca aactaaatgg ctacaagaag cctactttaa aattaaagat ttggatactc 172740 tgaaagtaaa gggatggaga aagatataac atgcttacag taatcaaaag acagctggag 172800 tagctatatt gattttcaga cacagcagaa ttcagaacaa ggaaggttac caggcatgaa 172860 aagtggcaat acatagtgag aaagggccaa ttctacaaga atatctaaac gtgtatgcac 172920 ctattaacag tgtcaagata tacatgaggt aaaagttgat aaaactgaaa aaagaaatag 172980 ataaacccta tttatagtca gaggttccaa catccctctg gcatagacat aaataagaat 173040 attgataacc tgaacagcat tatcagttaa gttgtttgat gtttatagag tactccaaca 173100 acagaagaat ttacatgaat atacattatt ccaaagttta catgaaatat tcatgaaaac 173160 atcatattat gtgccataaa acaaatttaa aagattataa atcatactaa gtactcaggt 173220 cacaatgtaa taaaactaga aaccaataaa gaaagacata gctgggaaat ctccaaatat 173280 ttggaaacta aacaacaaac ttgtatataa tagacacatc aaagaacaag tcattagaga 173340 aattaaaaat tattttgaac taattccagc tggacaatac tggttacaat ttgtgggatg 173400 cagctaaagt agtgcttgca aggaaatttt tagcattaaa tacattaaaa agaaaaagac 173460 caataatcaa tctgaccttc caccttagaa aaatacagaa cagtttaagc aaacagaaga 173520 accttaagca aacagaagac aagaaataat aaaagaataa aaatcaatga aatttaaaac 173580 agaaaaacag tatggaaaac caagaaaacc aaaagttgat ttgtttaaaa gattggtaac 173640 attgctaaac ttctagtcag gctaagcaaa gaaaagaaaa aagacaaatg accaatatca 173700 ggagtaaagg aggggacatc agtattgatc ccatggacgt gaaaaggata acagaatact 173760 aagaacaact ctatgcctcc agatttgata aatgaaatgg accaatacct tgaagtaaac 173820 taccacaacc tccaaaagga aaaataggta acctgaatag caatatatct attaatgaaa 173880 ttgaaataat aattaacctt cccccaaaat agcaccatgc ccagagagtt ttactagtga 173940 tttttactaa acatttaagg aagatgcaat accagttctc caccattact tccagaaaat 174000 agaaacagag ggaagacttc ccaactcatt acatcacacc atcattaccc taacataata 174060 accagataaa aacattaaaa gaaagaaaaa ctacagacca atatctctca tgaagattga 174120 cgtaaaactc cttgacaaaa tattatcaaa tcgaattcaa caatgtatag aaaaaattag 174180 taccattatg tacattatgg gatttattcc aggtatgcaa ggctctttga acattcaaaa 174240 ttcagccaat gtagtagacc gtatcaatag cctacagaag aaaaattata ttattatatc 174300 aatagatgca gtaaaagcat ttcacaaaat tgaatattca tgatttttaa aatctcagca 174360 atctaggaat acaaggaaat ttcctcaact tgatgaaaaa attctacaaa aaaccccata 174420 gctaatatca tactgaaatg taagagactg tatgttaatt tcaggagcaa ggcgaggatg 174480 tcctccaatt ctatgcaaca tcatactgga agtcttagct agtgcaacaa gacaagaaaa 174540 gggaatgagg catacagatt gtgatggaag aaataaaaca gtctttactc aaggatgaca 174600 tggagaaaat cccaaagaat ccacaaaaga aaaacttgga gctaataagt gagtataaca 174660 aagttaaagg atataaggtt gatatacaaa aaccaattgc ttacctataa accagtaata 174720 gtctattgaa attagaaaaa aactataata gcaccataac aaaagcaaat aaaaccctta 174780 cttataaacc taaagaaaaa caggttcagg atctatatgt ctatatgtag aagactataa 174840 aactttgata agagaaatca aagaagatca aaataaatga acagatatat cctgtatcca 174900 tagatagaag actcaatatt ataaaaatgt cagttcttcc taactttata gactcaattc 174960 aattctattc aaaatcccag caggctattt tgtagatgtt gacaaagaat aaccaacata 175020 acactgaaga agcacaaaga cagaggagaa atactacctg attttaagac ttttactaga 175080 agctgcagta atcaagactt tgtggtactg gcaaaagaac agatacataa gttaatagta 175140 cagaatagag agcccagaaa tagacaccac acaaatataa ttaactgacc tgtgtcaggg 175200 aacaaagaca atccaatgca taaaagaata gtcttttcag ttaatggtgc tgcaacaagg 175260 agatgtctgt atgtgaaaaa gtgaacctag acataggttt tagatatttc acaaaaatta 175320 actcaaaata gaccatagaa ctaaatatga aatgcaaagt gttaataatt ctaaaagaat 175380 acaagagaaa atgtatttga tcttgggttt tgtgatgggg aacaccaaag acacagacca 175440 tgaagggaaa aaaatggtaa gcttttaaaa tataagttct gtttggaaaa aggcacttaa 175500 ttaaaagata agccacagat tgggggaaaa tattttcaaa gtacatatct aataaaggta 175560 ttctagtcaa ctgtatagag aactcttaaa actcagcaat aagaaaacaa atgaccaatt 175620 aaaaaatagg caaaagatct gaacagacac cataccaaaa aacaaaaaca aatacaaatg 175680 ataaatacac ttatgtaaag atgcttaaca ttttctgtca ctggagataa aaaataataa 175740 aataccacta cacatgtact catatacatg tacacagtac acatatacac tacacacagt 175800 acacatgtat tcccatgtaa tagaatggct aaaatccatc caaagcctga tcatgccaac 175860 ttctgttgaa aaggcaagca acattaattg gtgatggaaa tgcaaaatag cacagccact 175920 tttgaagaca gtttggcagt ttcttagaaa gctaaatgtt gtcctgccat atatctagcc 175980 actacgctcc ttggtattta cccaactaat ctgaaaactt acgtccacat aaatgccagc 176040 acatgaatat tacagcttta ttcataatga ccaaaacctg aaattaacta aaatatcatt 176100 caataggtgg atggataaac tgtgatacat ttatacaata gaatactatc aagcaataaa 176160 aaggattaac ccatcaagcc acacaaaaac atggataaat catagatgca tattgctgag 176220 taaaagaagc caatctgaaa agaatacata caatattctt catttttgta acattctggg 176280 caaggcaaaa ctatagatat caatggttgg cagggttcag gcgaaggggc agggatttaa 176340 tagataaatc acagcaaatc tattctgtat ggtactgtaa tagtgtatac attatactgt 176400 gcgtttgtca aaacacagtg aactttaaag cacaaatgaa ccttaatgta cacaaatttt 176460 aaaaaatcat ttaggagttt gggggatcca agatggaaca cagtgtctga caaaagaatc 176520 caggtgtttt acaaatgtat tagacaagct tacgaataat gttggggaga aaagataatg 176580 acttaagtaa ctttgaaaat gagtggaatc tgttaagact agaggcaaag tgactgtaca 176640 ggagcactgc acactatttg ataaagttgt tttctgtagg tgtatgagtt agcaattcta 176700 aatcatgata catatgtata ttggaattga acaattaagt aaatggttgg cagatggtgt 176760 acattttctt attgttggaa tgaaaagtta cagacaagaa gaaaagaatg atttgtgttg 176820 taatggatta gagttggaaa cgtcagtgta aacttatgtt tagtttaata tgcagacaga 176880 tggttacaca tagaaatata gatgcatgta tttacatagt tattgtacac accctgtgtc 176940 aactgagaat gcttagaagc aatgacactc tagtaacaat gggcacacct agaacccagc 177000 ccttagtttc taataccatt ctccaataga acaaatcagg gatccttgta gaaatggctg 177060 attctaagac tggttaggaa atgtacaaga tgagcctgga gcatcatata gtgccagaga 177120 gtaaggaagt actaaaacaa gaaccccaca ttgatgaaag tatatcaaag ggactcagga 177180 accaaccaaa agagcttcca gtggtcaaat ctggaacaaa tttttaaaaa taaatagcat 177240 aatattagat tacaacccaa agtataaaat atccatgaat ccatattgat gtaaataatc 177300 aaatgaataa ataaactggg gagaacatag attttttgtg cagaataatt tcatatagtt 177360 tttatagata cttttgccct taaggaggtt gaactcctta ctcgtcaagt gtgggaagaa 177420 agtcattagg cacattggtg actttctttc aaagagtaca gggtggaaat gggggatgga 177480 agggaagagt aactgtgcag gggagaaacc tgacaagcac tatctctaca tggtaatcaa 177540 ggttaacatc agtagtgata aatcatgctg atagtatata cctttgatat gacgtgataa 177600 aaattgcact ttacctctac agtcttcctc ccaaaaaccc ataagatcag tatcattatg 177660 agaaaaatca tcaaacaaat cccacatgag atatactcta caaaatactt gactagtttt 177720 gctcaaaact gtgaaggtcc tcaaaaagga aagcttgaga aagtgtgaca gtcaagaaga 177780 gcctaaatag acaagacaac taaatggaat atggcatcct atatgggatc ctagaagagt 177840 aatagtacat tatgtaaaac tatggaaatc tgaataaagt gggctttagt taataataat 177900 ctatcaatat tggttcgttg agtgtgacaa atgtgccata ttaatacaag atgttaacag 177960 gaggggaaac tgggtatagg gtatttggga actctgtttc agcttcactt tttaaaaaat 178020 cttcaaatgt ttacttcaaa aatgaattca aaatcactca atgtaaatca ctatggtaac 178080 ataagagaga agaaaagtta tatgatcatc tcaaaagaga aaaagcattt gataaaatat 178140 aaaaactatt ctttataaat ctctttattg gaactacgaa tttatgggaa ctaaaaattg 178200 aaaaaaattt aatgagataa agggtattta caaaataaat taattgtaaa attattgaca 178260 gtggagatag agaaagcttt tttatgagat tgggaataaa agaggatttt ttttcatcat 178320 ttctattcat tactatactg gatgtcctaa ctaggggagt agagtcatag aataaggatt 178380 ggaaatggaa aggtataagt ttcattattt actgacaaga aacaagtctg aacatgatca 178440 attaaaatta ggaagttaat tgagcaagat tgctgggtta aaaagcagat aactaaaatg 178500 tatttctatg taaaatgaca aatgaaaaat gaagttttta aaagataaca tttttgggaa 178560 catcagaaac atcaattcca taggaaaaaa ttcacacaaa atattatgaa acattatgga 178620 aaggaagcaa gtaatacctt acaaatggag ggatataata tattcacagt ggcaaattca 178680 attacatata ctatacatgt taattctccc ccaaattcac ttaaagatcc caacgtaaga 178740 gcattctaaa tctgaatgcc atttattaaa tgttcaatct aatttcaaga attatatatg 178800 acacaaaaag tcaagaagag ccaagatagt cttgatgaag atgacaattt tgcatgagtt 178860 acatggccaa aatttaaggc ctactattgc aaggttacag ttactgacaa aagacagaaa 178920 actagcctaa tggagcaaaa tagagactcc actccacaag cagatcaata gatatatgat 178980 tacttgcttt atgataaaag tgccactcct gcatgatgag gaaagaatgg tttgttcaat 179040 agttagtgct ggatatcaat acataaaaaa gtgaattcct tttcaaacca tacagatcca 179100 tcatttctag gtgtaatgtt ggtctattca tgaaaggcaa aacagtaaag cttcttgagc 179160 atagcataac ataggagggt gtcatcataa tttggcagaa agtgaaaaat accaataaca 179220 ctaagcataa aggaaaatat tgatgaatta gtctgcatcc aaattaaaat ttttatttct 179280 caaagtatat aatcagtgaa gaagcatcgt ataaaagata caacttgtac atgtcaaaaa 179340 gttagaaaac acttaaatgg gtacttcaca aaagaggata tctgaatggc caataagcct 179400 atgaaaaggt attcaaggtc attagccatg agaaaaataa ttcagacaac aatcagataa 179460 acatcttcca gtatatctag acagtcccca atttataatg gtttgattta tgatttttcc 179520 actttatgat gttgtgaaag tggtatgcat tcagtagaaa ccataccttg gattttgaat 179580 tttcatttcc cgggctagcc actggcagta tgatactcta gtgaggctag gcagcagcag 179640 tgagccatag ctcctagcag tcatgcagtt atgaaggtaa acaaccaata cttcatcgcg 179700 tactgtgctg ccaccatttt gacccactgt aggctaatgt aagtgttctg agcacattta 179760 aggtaggcta ggcaaagcta tgatgttcag tacattaggt gtactaaaag cattttttat 179820 ttacagtgtt tttaacttat agtaggttta ttaggaggta actccttcat aaatcaagga 179880 tcatctgttt aaaatttgaa agtgtgtgtt ttttagaatt ctcttagtat tcactgaagt 179940 tgaatggagg caacatactc tcaggtatat ggttaacaaa aattcatgca tgattgaccc 180000 aaaatatgta tacatgaatg cttatcatgg tgccatatct aatagcaaaa attgaaaaca 180060 aagtgcccag gaggagttga aggataagta aaccttaaaa tatgcacata ttctctcaag 180120 gaacgtggat agtattgtga ctgattcttc tccatgtgtg atccacatag atgataagat 180180 catcatgaga agaacttaat tttatacttg agctttgctt tgactgaaag atgagaaatt 180240 ttgtgattat tggtatcatc tctatgatgt catattacct agattcacat attcttaact 180300 ccattaaaat agaaattata tttgtgggcg gggaacttat tttcatccat ctctgtttcc 180360 ttccaattga gcaattcctt attttatgtt aacctgattt tagtggttca ttgccataat 180420 tcttagaaat tatatctcat tttttcctgt gattttactg tattgaagta aatctggttg 180480 gcaggatata caatattaca tgaatgaaat ttgcctttgg taactgagaa agttcaaata 180540 gaccttggtt ctagcgaaga cttgtttcta aggaatttag attcattctt tcagacagta 180600 tgaatatcat tatggggtct tcttcatgag ttatgtatgt gatgggattc ttgtaagatt 180660 ttcacctttt acctgagctt gccttgactg aaagttgaga aaattttgtg attcattggt 180720 ataatttcta cagtgcaata tttatttgga tctaagcatg caagtaaaaa aattcatccc 180780 tgttatagta tttcaggttt gcagtacgtt atgacatttg tagatcattg atggactatg 180840 aatattcaag ggacctggca attgtaccca ggggattgag atccagatac ttgtttgttt 180900 gcccatagat ataaaattag gagcttcctg atatctaatt tactttttta ggaataacac 180960 ccatgagata cagttctcat ctactgccct actcctgtcc ttagataaat aacaccggaa 181020 gaagaagact ctctggcctc ttacatcagg gacacatgaa aagccacact gaatatgtat 181080 gaactccaat atactttcac agaagggttt aaggatgcca tccctggtta taatttttag 181140 gaccaaatat atatatatat acacacatac acacacattt aggatagata tatatttagg 181200 atatatagga taaatatata tatttagtgc catggtttgg gtcatgagga ggtttgatga 181260 cataaaaatt atgctcataa gtattatgct gagacccatt cttgggagga gatgtggggg 181320 tgtcctaggc tgtgcaaaac atagctatgg aaacagaagt tattaagaga aaagaacaag 181380 cagtcagtga gaatttagat aagagactgt aatagaataa aagtatcaga ttagtgaatg 181440 gttgtcctag taatttggaa gaaaaggaat aaaaaatgga gtcagactac taaatggcaa 181500 aaataaagac ttgaagaact taattttata cctgagcttt gctttgattg aaagttgaga 181560 aatcttgtga tttgtcggta tcatcatctc aaatcaactt atttttcatc tcaacatgaa 181620 gaatatcagc tctagccttt tggaatttca gcaactcaga tgcttgttag aacttatcca 181680 ggactgcttg caggacccaa aatactaata atccatatgc ctttttttcc agctgaaatt 181740 agctgtctta agagttgttt ttcagtgctc tgaggatatc cacaaatata tcccaaggca 181800 ctctgaagtg tgttttcaat ctttggccct gcacactggg gatgcccact ggatgttgca 181860 tggagtgttg cctccagttg actttgatag acacaataaa caccacgtga gagccccctc 181920 atgaaggagg gctgaggact tggagtccaa ttctccacct cccctgacag ataggctatt 181980 caatgccttg ggaatccgac atgaaggact gcttatagca gtccttgaaa actttctaca 182040 gaatgtgaac tgggagaagc taaatgctgt actcacaagc tgggtgactt ctccattgat 182100 ttttaccata gctcactgaa acattttcta aattaacagg tataaattca cagacagatc 182160 agaatagatc cttggtcctt tccatttttc tggcactttt gttgccagga attcaaatac 182220 aactaagaga aaaagtgggt agctagcaag aacagatagt ttctcaaata ttagtggcag 182280 taacccaact ttgagaaaat atggagaaag agaagaaaaa acccttaaga ctgcagtgtt 182340 agctgcccag ttacaattat tcacaaagtg agcaaatact tatttgggcc accaataaat 182400 aagagggcac aagctaacgg gaaattaata cgtcactcat gtaaaaagtc aacacattag 182460 aaaaaggaat cttggatgag attgagaaag atgcaaggga taaaacctga caagctttac 182520 aacctccttg aggaggtctt ccctactctg taaaatcaga cagaaaatca ttggcaaatg 182580 gagcaaagca tgggcaaaac tgatataatg aggaaacaga gctgggaaag gataaattta 182640 tgtgtctgtt tctgtttcct atcttttaat ccttttttac cctttcttct ggatactgga 182700 gcaacgtatt ctgcaatttc tacaggcctt ttctgtttta tcctaaacta ggaaaatatc 182760 cagatataag tatttctgga ctatctgcta cctcttcttt ctcctctgag gttttcatgc 182820 aaataggcga ggtcctattt gcataaaata ggaagaatat gccttgtctc ctaatatgcc 182880 caataatctt ttaagaaagg gcctgctgtg taaaccaagg gctatgatct tctgtactct 182940 gaagagagtg cttttggagc ttctgggatg caaggtatct acattgctaa atatgtgctt 183000 tctgaaacaa aagatggctg tgggagagta ggagtctcac tcaatgctgg agaagcactc 183060 ccaagttaca gaaaataaac ccatatctat gagtcctagg aacaaatgat aaagatttaa 183120 caaaagagat caataccatt gttgtaactt acaacagaga aaaaccttgg ccatgtatag 183180 aacattttct ctatttttac ctcaaatatg atgtaattag aaaaatttta aaaaacgtgg 183240 catagttaaa aaaaaatggc acattcactt cataatgctt ccatattgcc tgtgggaaag 183300 ttaggaaaac ttgacaggga aggtcaaact gtttatagat ttatgcatga tcttagagaa 183360 acaagttgtg attcctctga cacttgtaat tcccagcctt gccactgttt taatatctgt 183420 tcctgagtta tctaagtatt tttctgtcat ggatttatgt tcaatgtttt gttctccatg 183480 tttagctggg gagtcgaggt tcctgtttga gtttacctgt ggagcgggag gctttcaata 183540 tttgtggcaa cggatcttcc tggaattcag agagtcacct actccattct ctgggcattt 183600 ataagaaaat ataaagaata ttcctcacat taggattcca tactaattgt tattgatagc 183660 tgctaataac ttacatgcta gtaaagaaga cattttagct ttactaaatt tcttagactc 183720 ccaggacgta aaacctcgct agctaagttg caatattacc aactgaagta aaatatttgg 183780 gatctgtgtt attggcagat ggaaggtggt tgcatcttga agtcagccta atatacaaat 183840 gaaacaacat gccaaaaaaa aacttcaccg attttgagga ttaattgtag atctttgcgt 183900 tttatgaaaa ggctaagcct ctcactgaga tgttacatga aacatcacta gaactcttta 183960 ttaaagtcaa aataaggctg aagaagtctt ttatgccctt aaaatagctg ctatttcttc 184020 acttgtatta cttttttaac cttgttaaaa aaggagttct accttttctg tcttgagatt 184080 aagggttact ccaaaattag gccttgatta taggcacatt gcttactttc ccaggttctt 184140 gtattttgtc tctctggaaa tgcgatgata tttataaggt acagtggcaa ccactcccct 184200 gattaaaaag gctcattcag tccttgactc tgagaaattt aacttactta caggtacttc 184260 atgttgttac tgctatttta caagttcata agacacaaca cttgtcagta tgctgtcaaa 184320 cgagctaaga acaagtctta ttgtgtgatc ctaatgctat tctaggaagg tgtaaccttt 184380 tgacagctat tctgtggcca gatcttgaca gaataagttg aacttgactg tctcagagtg 184440 attgaggaag acactggagc atggtctaat ttttgtaata ttcctattcc caatgttgac 184500 tgaatattca tgaatatatt ctgtgtgaaa gacccacaaa ggaatataaa agcatgttct 184560 acggtaatca accctcatga agcttagagg cttctgtttt tcgaaacata aaatcagccc 184620 aagtggcaga attgtagtta ttataccagc tgttaaatta gccaccagtt ataaagcaga 184680 tatctatact ggtaataact atatgtttgt ggtctgttat gtgactagcc aactttggaa 184740 gaatagatgc taacgtcaat aggaactaaa atattacatg agaagctaat ttctgattta 184800 gtagagtcat tcaaacttct ctaacagatt tatgtaattt attgtagagc tcacagtgga 184860 aaacaagatt aactctttaa aaagaaatta atttgcagac ctagctgtga agggcttctg 184920 acgtttagac tggggaaatc aaacctctat cacttctgtc caaaacctcc tattcataat 184980 ttcagaaata gccaactctc ttaagaatta gaaaattagg aatgaaggag aactaagatg 185040 aacaccatag gaaaatgaga attacataat gaaatctttc ctttattccg attgttatat 185100 gattgagtgg ctttttcatg ccaccaacaa gttcgttcaa gcaaaaggaa tatgctgaca 185160 acttgaaatc tttgtaatag catcatataa ttcaggaaat aatatgaaga tatgctcttt 185220 gtcagaaaaa ttctttcctt acctaaaata agtcaagaaa gcctactaag gcccatgata 185280 cctaggatct gctggcacaa gaactttata gaacttccac ctttagaaga tagtaaatat 185340 ttttaccagt gttgtgtatt ggtgtctgga taggctaaag cagatgctca aacagtgatc 185400 aagctcttac tgaatcatat catctcaacc actggaattc ctgaatatct ggaattcagt 185460 aggggaatca ttctgtattt gtgggaattc gggaattttg taatactcta caaataccaa 185520 taatttacct acctgttatc cccagtcttc tgaacaagtg gaatgagtga accacatacc 185580 ctaaagaatt atttagctga attatttagc taagttatgt aaaaccttac catccgtttc 185640 atttaaaata agattaaatc cctctagcaa gcccaacatt actccctttg agtttggaag 185700 gtctactaat cttgggctta agcctaaccc tttctctgat acaatggaaa atcctcatga 185760 ccatatatga tacttaaaga gtttgtgggt ttccctaggc tcaccttgcc aacatgtggc 185820 cagatgctga aaaagccgcc tggggaagtg tgtcattgat attgaacagg agattcagtc 185880 tatatcaaag tgttctgatg acagactgtg accacactgg acagaaccct atcaagtgtg 185940 gttgagaatt catagtgcta tcaagatgaa ggagaaaccc aagtggatac acgcttcaca 186000 tgtgagacca acatccacca tcgagtgggg tataattccc atttaggacc ttaaggataa 186060 attctctaga tagtaacctt gaataatatg caagctaaag agaaaaactt atttgataga 186120 cagcaggaga gatagactgt tttgttatta atacgttctt cttaattatt ttgaccatta 186180 taattttgat acttagtttg tattaatttt gatacttagt ttgtatcaat tgaacataaa 186240 gcttattatt agtctttctt ttaaaagtta gtatctcaac ctcaaggaat tttgtggtaa 186300 ttaaaaattg tcctgaatat gagatcagga cttaagaaac ccctttcttt gtcataatac 186360 ttcaaactca ccaactggat gatttaaatt cagaagacat gaaaaatttc aaatcttccc 186420 actgattagt caatattaca aaaatcttaa atatcatcac cctttgtgtt attgaagata 186480 ctgatgagaa gaaattttta actaattaag ttgaacgtaa ttatattcaa attgaaagtc 186540 cctgaagggt atcacaaaac tccaacaact ctgtatcttt tttttttttg agcagagttt 186600 caccttattg cccaggctag agtgcaatgg cacgatcttg gctcaccaca acctctgcct 186660 cccaggttca agcgattctc ctgcctcagc ctcctgagta gctgggatta tagacatgca 186720 ccaccatgcc tggctaattt tgtatttttt gtagagatgg ggtttctcca tgttggtcag 186780 gatggtctca aacttccaac ctcaggtgat ccacccgcct ttgactccca aagtgctggg 186840 attacaggtg taagccacca cgcccggccc aactctagat cttaaatagc catgggggtc 186900 caatttaata aagcttaaat agacacacag atgagaaaat atcccagccc aaatggtgag 186960 ggttagtttc ttcaaaaccc ccaaaacgta tcatcaccta aaaatgagct taccctgttt 187020 agaacctggc agtctccagt ccccatactt acaaactcga ggataattaa atggtctgta 187080 tcatttaata ttacaatagc taatgtgagt aaactgaatt ctacttgtac atgataggct 187140 ttaccactat gaaatgtttt tacacaggga ctaaaatggc actatgatca aactgaaaga 187200 gatttctttt tttaatagat ggggtctggc tttgttgcct acactggagt gcagtagcac 187260 aatcatagct gtctatcgcc tgtaactcct gggctcaagg gcttcctccg tctcagcttc 187320 ctgagtagct gggactacag ggacatgcca ccatgcctgc ctattttttt ttgtagagtc 187380 agggtcttgc tcaggctggt ttcgaacttc tggcctcaag tgatcctgct gcctcggcct 187440 tccgaagcac tgggttcgca gacataagcc accatacctg gccagagatt attaaataca 187500 gtattagggg gaataaaact aggactacaa ttgtaaactc ttctgatata gaaacaatta 187560 ctgataaaca gtgcattgga caatttgcag aaagatgcaa acatgataga atcaaaatct 187620 aaacaagata tgacaaagaa aaacaaaaat ggaattggga aagcatttgg aattggacat 187680 ctggtaataa aattctattg caaaaaaata tatagtaaag aattttcaga agccttcact 187740 tgcattagtg cacaaccact ggttattcaa caactacaat gtatacttgc tggtactgaa 187800 gtacaagatt atacctactc agacaaacaa ttaggtattg gacatactac tgtctatgta 187860 gagattaaat gatagtgtaa aaaggttgat catattatag gtaaaagagc tgaaatctgg 187920 cattgcagat tgaaatttct gaaaactgaa ataataaaac taatttcact aaagtatgta 187980 cattttctta tttacatagt ttataatgtg ttatataatt catgaatctt caaaagaaat 188040 atactgagct attcaataaa aatttacatt acagctttag gccaccaagc cccatctatt 188100 gattatgtac ttggtgtaaa ttggcggggg gaacaaaaca agagtgaaaa ctgagcctca 188160 aaatacaaag catgtagcaa aacagactac taaaattatt ctcaatttct aagcccatta 188220 tatgatgcag gagaattctt atgtgtaggt aataaagaat ctgttcaaat atgcatcagt 188280 ggtatgacag tttcaaataa cccactgaac taggaaatat tcaccaccaa ggaggtcagg 188340 tatactgatt tggtcaacct ggatattgac atgggatgtt cttacggatt gacagctcca 188400 cttgatgcta tcctatcaca aaatattatt acctgatgtt gatataatta acaagtcaat 188460 acaaaaagta aggtctctct acaagacaag actaacatct ctgtaatata aatgggactc 188520 tgagtgtaat agatttaggg tttctgcaag aattttgaaa gttaaggatc caacgcctgt 188580 aatcccagca ctttgggagg ccgagacggg tggatcacga ggtcaagaga ttgagaccat 188640 cctggccaac atggtgaaac cccgtctcta ataaaaatac aaaaaaaaaa aaaaaatagc 188700 tggacatggt ggcacacacc tgtaatcccc gctactcggg aggctgaggc aggagaatcg 188760 cgtgaaccag ggaggcagag gttgcagtga gccgagatcg taccactgca ctctggcctg 188820 gcaacagagc gagactctgt ctcaaaaaaa caggaaagca aaagaaaaag ttaaggatcc 188880 taccaacaaa attggaatat gagactgagg aaattcctat tccagctaaa cccagaattg 188940 attatgttga tgaacacatg aatttcatgt gtgtgaaaac atatgaactc ctcattgtca 189000 gtctaatgag agtgaaaaca acacatcgaa gatgcgggga gacgacaata cagagtgggc 189060 tcataactgc attctagata ctgggattac tttccattaa ggtatataat tttagaatat 189120 ctcacaaata gcccatgcaa aatcctgcgg aaaggcaacc ataaatatag agagaatatg 189180 taaaaaagtg gcatggtcta gtatatgcca aacaaggcaa gggtatacaa aaacctcaag 189240 gtcccagtat gacaaatcat gcttgtattg cacacccatt aaaaagtctt ctaaaaagtt 189300 tttttaatgg tgtgcaggca ggtttattca gaaaaagctc ggattcatac ttgtaaaagt 189360 ctgagaaaag cattaaaatg ctattatgat acagttgacc caaacaacac aggtttgagc 189420 tgtgcaggtc cacttatctg tggattttct tctacctctg ccactgagac agaaagacaa 189480 actcctcctg ctcctcagac tactcagcat gaagatgagg atgaagacct ttaggatgat 189540 tcacttcttc ctaatgaata gtgaatgtat tacttcctta ataacgtttt tttttctcta 189600 gcttcttgta agaatacagt atataatata tgcaacacaa aaaatacgtg ttaatcaact 189660 gctttatgtt atcagtaagg cttccagtca atgggagact aactactaat taagtttttg 189720 gggagtcaag ttatatgcag attctccact gagcaaatgt tcagcactct taactcctgt 189780 ggtgttcaag tgtcaactgt atatatgttt aagagttatt gtttacccag tagatcaagc 189840 caagaccaag ttaggtttat gtgtttttgg cttaacctaa gaaaatgttc agactaaagc 189900 agtccatcaa tagaacagac tgccttttaa accagggaac aacttgtctt tgtaggtatt 189960 ttaggtatat gaatgaccat atgtgatctg ctttgggtca tctatggtcc cttccaactt 190020 aaaacttctc tattcatgaa cattgcataa ctgaattgtg gatttcatat aaataatatc 190080 ttgttgccta ctttaggttt gaaatgtttt ccttctcagt tgcatagata tgtatagcac 190140 catccccact atgaactctc atgtagaaaa taccagattc taaagtcatc tgtgaggcta 190200 aatgtcagac ttaggcactt ccacataatg ctgcaaaaag caacagctta aaggtattac 190260 ttgctcaaca tgtcattcca aacacataca ctatgattag cagctgaatt taacagtatc 190320 tttccacttt gaaaaacact ttatatacct ttacaaagaa gccatagtat ctcagggtag 190380 aaaaactcaa caggtagaaa acatggcctt ctcttagaaa tgagctacgt aattttgagt 190440 acttatctca aaatcattgc agaaacatat ctagtgctta tggaaaaaga atcaaaagat 190500 cttttttttt agctaaagat tttgagtttt tcttgtgaca tttaagtctt ttaatgtatg 190560 ctgattttta tgattatcta actgtttcat aatggttatt cttgcctcca tgaaagggaa 190620 gactagaaca aaaacctgac aagaacaagt tctagctcca tcaccgactt actgagtgac 190680 cctaggcaaa tcatgtgggc tctttcttgt gttttaagtt ttacctccaa tgaagtaact 190740 gcctcagact agctgtgaag ctctcataaa gtgatggatt tgaaaatgcc ttgcaaagaa 190800 tgagcagtta atacatagaa agtttcatgt acttccgtat attgcatgat gcccacccag 190860 ggttaggttg ataacagttg ttgatccaat aatgaaagaa ataaaaagaa ctctttaaaa 190920 taacgaagta aaatagctaa ttttcctgtt gtagttttaa aaattatata aactatataa 190980 ctaaacatat ttatgtttat tatatataat atgatatgca attacataag acattattat 191040 ataatgtttt tatataatgc ttaagtaatt aaacaattat atttaaatat aagttatact 191100 ttccttcccc agataagaca aagaacctgt ttacttctct gagggattta ttggttcctg 191160 tgaaatctgt ggaggccgct aacactccat agccagagaa tgacaacata tgattttctt 191220 ttcagtcttg tagtatccac agtagtgatg tctgtccatg tacaagtgtc tgtccaggac 191280 atccattaaa ttccatgcct gctctgtgtg ttatgagggc agggacagaa gacagattca 191340 ctggtggtac tttcaaacaa tgtggtaggc cttccttttg gggtctgcca tgacaatgat 191400 accccaggcg gcaatgctaa ggcccatgac catcttcata atggtccatg gacccggggg 191460 gtatcccatc ttcatgggct tctgtgccac ccagtacaca tacccgcctg cccccatcag 191520 ccgcaaccca gaaagcacgt gacagctcca gcaggtctcc aacaggtggt gttctgctgg 191580 tgaggtcggc gatccgggtg tagctggggt tgcaggcttg gcaggcacgg cggcggtatc 191640 gggaggcaca gcgatcttga gggactcaaa aggctgggac aactgagacc ccgtgttctg 191700 gaactcggcc tccctaaaaa ttatgtttta aaaaatacat agaatcggta agatgaggaa 191760 aaagcataaa acggtcaaaa acactgggat aattcaaggt tcattttgac aatggtaata 191820 caaatagaaa aactgacaaa aaagaaaata catcttacat tagaaaacat acaagagtag 191880 ttgtatacaa acgaagacac gtaccaaaaa taagttacaa aatatgaatg catatacata 191940 aaaaatgtag tttcaaacaa ttcaaaagta aaatgatgca agacattaaa atattcacaa 192000 acacgctcga aaaataagag ctgacgccca aattagacca gttcaacgga agtgtggggt 192060 gtggttgggg atccgccgca gaaatcacgt ggcgcccagg ccaaggctgc aatttcccat 192120 gctgcttgga gaagacgcct gggagggctc ccaccatgcc caggggcagg ctatgtgact 192180 gcccggtctg cagctgtaag tggtttctgg gccagtctct ttgtctggtc atgacctggt 192240 tggtggccct agcttgtgcc gagtggtccc ggagtggccc agggggttgt gtgtggggag 192300 ccagcgtggg cagcggaggt gctccctggg gcctgcagta gggcacagcc tctgcatctt 192360 gtgtgagccc agtgacccgc ctgtcctgtc cttccagggt tgggtggcag ggagggccaa 192420 gggtgccctg cgtccgtgac gggtcagcgt ttccagcaaa tgggtccatg gagggagagc 192480 ctagctgagc cggcgggctc taccaccttc atgaggttct gtttggacac ctgtcctact 192540 cctgttcccc cagatggtga ccatggagga agacttgtgt tgggcccaat ggccctcggc 192600 cagtgtccgt ctgccaggtg ccagcccccg gtgcgctgaa gctcaggcca ttcctgatgc 192660 cctggcctcc tgcactgagc tgtggtgagc ccatccgggt cctgctggat acatgggcgg 192720 ggaggggggt gccctgggtt gtgttgatga tgagaacctt atattatcct gaagagaggt 192780 gatgacttaa aaatcatgct caataggatt acgctgaggc ccagcctagg tgagaatttt 192840 ggaagaggat gctgggatcc agaggccccc gacggggcca ctgtatttcg ggctgcagac 192900 ctagaggccc tgaagggcat ctgaaggtgg cccaagccta tctctgagca accccgtgag 192960 gcagtcaagg atccctgtgt gggcataggc tggggctctg gttccctagg ggcagggcat 193020 gtgggtggct cctccctgac ccccattctc ccctgtgtct ttcagtgagc tcttctgccc 193080 aggcaggccc cctggcattg accggcatag gtgagtggat cctgctgggg tcatgggcca 193140 tgagccaggc tgctggggtc gccaagggtc agcctttggg acaggagggt ttccttaggg 193200 agccaacctg aatccccact ggggagggct aggttctcca ggagggcagc ttccttggga 193260 gtctgaccca aggaggatat cttctctaaa gccctgcagt ggtgagggtg gtccaggcag 193320 caaagggttc cttcaacccc acccaggaca gcgcccagct gagactcagt gtgcaggtct 193380 ggccatgagg actgcccagg tcacataagg gggtccatag gagctccggg gcaccacagg 193440 ggtcacacag gagctctcct tccccagaga ggggtgagcg attgggccta tggggtcagg 193500 cctttggaga tcaaggattg ggccccaccc atgaacctga atgggactga gcctttgagc 193560 aatggaccat cccagtggtg cctcggagcc tagtcggggg tgatgtggct tcaagggggt 193620 tgggtcaagg ctgagctctg gccggtgcct ggtagtgctg caggctggcc ctgggactcg 193680 ctggctttgg gcaaaggggc cagcccgtgt cccactggag gtcacccctt ccctgtgggc 193740 aactagcagg aagggtggca tccttagctg ggaaggccca ctgtcgaggg tcctgtccag 193800 ggaatttgcc tcccaggctt cttctgatcc acggactcac ctccagggtg gtggggtctt 193860 gggcccgagg aaaggagaag ataccctgtg ttccccagtt ggctgagtgt ggcttggctc 193920 tgtgtttggg aggtgtgtag ggtatgaatg gggacccacc agagaacaca catggcccag 193980 ggccccaggt tatgatttcc catgcacact tggagagaac tctgggtgag tgccctccac 194040 tcccaggcac aggctatgca actgccaggt ctgcagtggc atgtggcttc caggtcagcc 194100 tccttggttg gccatgagca ggttggttgc cctgtcctgt gcccagtggt cttggagtgg 194160 cccaggggtc ctgcagggga gctggtgtgg gtagtggagg tgcttgtggg gcctgcaata 194220 gagcgcagcc taggtgcctt gcacgagctc agtgacccac ctgccctgtc ctagtcctag 194280 ctcagtgacc cacccccgct ttgcagtgat ggggagtacc aagcgtctcc tgcgtctgtg 194340 atgggtcagt gttcccatca catgggtcca tggagggaga gcatgcatga gctggcacca 194400 cccaccacct tcccactatg gaggcgtgag gccatgtttg gacacatgtc ttcttgtccc 194460 cccagacagt gagcctggag gaagacttgc cctggtccca ctgtccctgg gccagtgtcc 194520 atcagccagg tgcccagacc ccagtgcgct gaagctcagc cctccctggc actctggtct 194580 cctgcactga gctgtggtga gcacatccag gtcctgctgg atgtttgcat ggggaggggc 194640 tttccccggg ttgggtcgat gatgagaagc ttctgttttc ttgaagagag gtgatgactt 194700 aaaaatcatg ctcaatagga ttatgctgag gcccagccta ggtgagaatt ttggaagagg 194760 atgctgggat ccccggcagg agggattttg ggctggagac ctggaggccc tgaagggtat 194820 ctgcaggggc cccatccctg tctctgcact tgtctgtgag gcagcccagt ttccctgtgt 194880 gggcttcgtg tcagtgctct ggttccctgg agcagggcac gtgggtggct catccctgaa 194940 gtcacgttct ccctttgtgt ctttcagtga gctcttccgc ccatgagggc cccctggcct 195000 tgagcagcat aggtgagcgg atcctgctgg gctcatggac caggccacat ggggtcactg 195060 agggtcagcc ttcaggacag gagggattcc tcagggagac aacctgaatc cccactggtg 195120 agggattggt tctccaggag aaccacctcc ttgggaatct gacccaagga ggacaccttc 195180 cctgaagccc tgcaggagtg acagtggtcc aggcaggaaa gggttccatt agtcccatgc 195240 agggcagctc ccagctgaga cttggtgcta gggtctggcc tcgaggactg cccaggccac 195300 atgaggcagg gtctcaggct gctatttcca gtgcatgctt ggagagggag cctgggtagg 195360 ccccctccct gtgcaggggc aggctgtgca tctgctgggg ctgcagcggt gcctgccttc 195420 aggaccagcc tccttggttg gcttgagctg gatagtggcc ttggccccac ccaggggtca 195480 tggtgcagcc caggaattgc aggggagctg gcatggggag tggaggtgct ccaggggctt 195540 gcagtagggc acagcctggg catcttgctt gagcccagtg accagcctgc cctgttttcc 195600 agggttcagt ggcagggagg accaagggtc ccccacgtcc atgactatca ctgtttcaca 195660 tggatcccat caggtgggtc catggaggga gagcatgtgt gagtcagcac cccctgcctc 195720 ctttcccgca tggaggcatg aggttctgtt cggacacttt tccctgtctc tccagatggt 195780 gaccctgaag gaggacttgt gttgggccca atggcctggg gccagtgtct gtcagccagg 195840 tgcccagccc ctggcgtgct gaagtttggg cccttcctgg tgccctgttc tatcggggga 195900 acccgccccc aataattcaa cgtaggtcct tttctatttt ccctaagtgt cggccggtct 195960 gagaaataaa gggaaagagt acaaaagaaa gaaattttaa agctgggtgt ccgggggaga 196020 catcacatgt cggcaggttc catgatgcca cccaagctgc aaaaccagca agtttttatt 196080 agtgattttc aaaggggagg gagtgtacaa atagggtgtg ggtcacagaa atcacatgct 196140 tcacaaggca ataaaatatc agaaggcaaa tgagggcaga gcaccagggc caaattgaaa 196200 ttgctaatga agtttcgggc acgcattgtc attgataaca tcttatcagg agacagggtt 196260 tgagagcaga caaccggtct gaccaaaatt tattaggcag gaatttcctc gtcctaatag 196320 gcctaggagc gcttcgggag accagggctt atttcatccc ttatctacaa ctgtataaga 196380 cagacattcc cagagcggcc attttagaga cctcccccta ggaaggcatt ctctttctca 196440 gggttgttcc ttgctgagaa aaataattca gcaatatttc tcctattcgc ttttgtaaga 196500 agagaaatat ggctctgttc cgcccggctc tcaggcagtc aggcctgatg gttgtctccc 196560 ttgttccctg aacatcgctg ttatcctgtt cttttttcaa ggtgcccaga tttcatattg 196620 tttaaacaca catgttttac gaacaatttg tgcagtgaac gcaatcatca cagggtcctg 196680 aggcgaaata catcctcagc ttacgaagat gacgggatta agagattaaa gtaaagacag 196740 gcataggaaa taataagagt attgatttgg gaagtgataa atgtccatga aatcttcaca 196800 atttgtgttc ttctgccatg gcttcagcag gtccctccgt ttggggtccc tgacttccct 196860 caacactggt ctcttccact gagccttggt gagcccatct aggtcctact ggatgcatgt 196920 gtggggaggg gggtgccctg ggttgggtca atgatgagaa ccttatattg tcctgaagag 196980 aggtgatgac ttaaaaatca tgcttagtag gattacgctg aggcctagcc taggtgagaa 197040 tgttggaaga ggatactgga tgctgaggtc cctggctgag ctactgtatt ttgggatgga 197100 gatctggtga ctctaagggc acctgaaggg ccagaccctg tctctatgag gcagcccagg 197160 ctccctgtgc aggcttgctg ttggcactct ggttccctgg ggtgggacat attggtggct 197220 cctccctgag ccctgttctc cccttgtgtc tttcagtgag ctcttccacc aaggagggcc 197280 ccctggcatt gactggcata ggtgagtgga tcctgctggt gtcatgggcc atgggccagg 197340 ccacgtgggg tcaccaaggg tcagccttca ggaaagaagg gtttcctcag ggagccaaac 197400 tgaatcccca ctgggaagag atgggttctc caggagggcg gcttcctggg aaacaggaac 197460 caaggaggac gccttccctg aagccctgca ggggtgacgg tggtccaggc aggaaagggt 197520 tccttcaatt ccacccaggg cagctcccag ctgagtctcg gtgctcgcgt ctggactgcc 197580 ctgactatgt ggggggccac aggggctctg gggtgccttg ggggtcacac aggtgctctt 197640 tgtccctgga gaaaggtggg tgatcaggcc catggagttg agcagtggag attcaaggat 197700 tgcacctgac acatggtcct gaatggaacc caccctgttg agcaatgggc catcccatgg 197760 gcctcttcaa gcctgaagag gggcggtgct gtttcactgg gtttaggtca aggctgagct 197820 ctggccggtg cctggtggtg ctgcagtcta gctgttggac tcgtgggctt tgggccagtg 197880 gggcagcctg catccctctg gaagtcaccc cttccctgtg gctggaagtt accccttccc 197940 agtgggcgaa tgtggggaag ggtcacctcc tgaagtgaga aggcccacta ttgagggtcc 198000 tgtcctggca atttgctgcc catgctgctt ctgagccatg gagacacctc cagtgtggtg 198060 ggatcttggg cccaaggaag ggagaagaca ctgtgccccc cgattagctg agtgtggcca 198120 ggctgtgtgt ttatgaggtg tgaggggcat ggatggaaac tcaccagaga aagcatgtgg 198180 ccctgggacc ccaggtcgtg gtttccagta tgtgcccaga tacagcacat gggtgggtgc 198240 ccaccatgca cagggactgg ctatgtgact gccagctgtg cagcagcatc aggcatatgg 198300 gccagcctcc ttggttgaca atgaactggt tgctggccct ggcctgtgcc cagtagtcct 198360 ggggtgaccc tggtgtcata caggggagct ggcatgtgta gtggaggtgc ttgtggggct 198420 tgcagtaggg cacagccctg gcttctagcc tgagcccagt gacctgcctg tcctatcctt 198480 tcggtgttca gtggcggaga gagcattggg tgccctgcat ccatgatggg taagtattcc 198540 acatggatct catcacatgg gtccatggaa ggtgagcatc cctgagctgg cacaccacac 198600 cttctgtcca catggagggg tgaggttgtg tttgggcact tgtcctcttc ctgttccttg 198660 agatggtgac cccagaggag gacatgcgtt gggcccgctg tccctggcca gtggccatca 198720 gccaagtgcc tagcccctat tgcactgaaa ctcgggccct tcctgtcacc ttggtctcct 198780 gcgttgagct tgggtgagcc catccgggtg ccactggatg cctaggcagg gaggggggtg 198840 ccctgggttg ggtcgatgat gagaacttta tattgttctg aagagaggtg atgacttaaa 198900 aatcatgctc aataggatta cgctgaggcc cagcctaggt gagaattttg gaaggggaca 198960 ctagaatccc gaggtcccca gcagggctgc tgtattttag gctggatacc tcgaggccct 199020 gaagggcacc tcatggaggg gcccaatcct gtctgtgctc ctctattagg cacaccagac 199080 tttctgtgtg ggcttggtgt ccacgctcag cttccctggg gtgggacacg ttggcggctc 199140 ctccgtgagc cccattatcc tctgtgtctt tcagtgagct cttcccccca gcagacccct 199200 gggattgacg agcataggtg agtggagact gctggtgtca tgggccatga gccaagctgc 199260 gtggggtccc caagggtcag ccctcgggcc acctgggttt cctcaggagc tgatctgaat 199320 cccaactggg gatgtgttct ccaggagggc agcttccttg ggaatcagac ataaggagga 199380 ggccttctct gaagccccgc aggggtggca gttgtccagg caggaaaggg tttcctcagc 199440 cccacgcagg gcagtgctca gctcagactt ggtgcttggg tcaggcctct aacatggcca 199500 ggccacatga ggggggcaac aagggctccg gggagccaag ggcatctcac gggggctctc 199560 caaccctgga gaagggtggg tgattcggtc catggggtca ggccatggag attcatggat 199620 tgcagcaaac ccaggaccct caatgggact gaccctataa gcagtgggcc ctcccagtgg 199680 cacctctttg agccatttgt ggggcggcgc tgtttctctg aggttgggtc aagactagct 199740 ctggccagtg cctgatggtg gtgcaatcca ctcctgggac tcgtgggctc tgggccaagg 199800 ctgcagccca tgtcccgctg ggggtcaccc cttcattgtg ggcgagtggc agtaatggcc 199860 tcctgagttg ggaaggcccg cagtggaagg acctttcctg gaaatttgca gtccaggctg 199920 cttctcagcc attaggacaa ctccagcggg ttggggggca ggggcgggtc ttaggcccaa 199980 agaaaggaga agataccata tgtctcccgg ttggctgagt gtggccctgc tgtgtgtgtg 200040 ggaggtgttg tgtggggcat ggattgggac acaccagaga aagcttgtgg ccctggagcc 200100 ccaggctgcg atttccagtg caccttgagg aaaggagggt gggtgccctc catgcacagg 200160 gcagactgtg caactgccag gtaggcaaca gcacgtggtg tccgggccag ggtccttggt 200220 ttgctgtgag ctctttggtg tccgtggccc ctacccaagg atccagatac cacccggggt 200280 catgcagggg agctagcatg ggcaatggag gtgctcaagg ggcctgcagt agggcacagc 200340 ccaggtgtct tgcctgagcc caggaaccca cctgccctgt ccttccatgg ttcagtggct 200400 gggagagcaa agggttccgc tgatctatga cacatcagtg tttcccatgg atcccatcac 200460 atgggtccac ggagagagag catgtgtgag ctggcacccc caaccccatt ccctgtatgg 200520 aggcgtgagc ccatggttgg acacatgtcc tcctcctgtc cccccagatg gtgactgtgg 200580 aagaagactt gctttgggac cgctggcccc aggccagtgg ttgtcatcca ggtgcccagc 200640 ccttggtgca cttgagctca agcccttcct ggtgccctgg cctcctgccc taagctgtgg 200700 tgagcccatc caggtcccac tggatgcatg catggggagg agggtgccct gggttggatc 200760 gatgatgaga accttatatt gtcctgaaga gaggtgatga cttaaaaatc atgctcaata 200820 ggattacgct gaggcccagc cttggtgaga attttggaag aggatgctga gatcccaagg 200880 tctctggcag ggccactgta ttttgggctg gagacctgga ggccctgaag ggcatcttag 200940 gggtgcccga ccccatctct gcgctcctcc ttgaggcagc ccaggctccc ttgcgggctt 201000 ggtgtcagcc ctccagttcc ctggggttga ggcacattgg aggctccttc ctgagccccc 201060 attctcccct gtgtctttca gcgagctctt ctgcccaggg ggacccctgg ccttaagtgg 201120 gataggtaag tggatcctgc tggggtcgtg gaccatgagc caggtcgctt tgggtcactg 201180 agagtcaccc ttcaggccac gagggattcc tcagggagcc catctgaaac ccaccaggga 201240 cggatggttt ctccaggagg acagcttcct tggaagtcgg tcccaagaag gatgccttcc 201300 ctgaagccgt gcagagatga tggacgtcca agcaggaagg gcttccttca actcaatgca 201360 gtgcacatcc tagctgagac tcagtgcaca agtcaggcct ggaggacttc ccaggccaca 201420 tgagggggtc cacagggtct ccaggggcca cgggtgttat gagggtgctc tctgtccccg 201480 aggcttgcag aggggcaggg tgtgggtgat cggacttatg gagtcaggcc gtgaagattc 201540 aaggattggg cccaacccat ggcccagcat gggccgaacc tgtagagcaa tgggccatcc 201600 cggtggtgca tccttgagcc ttgtgggggt ggtgtgacct tagtggggtt gggtcaagcc 201660 tgagctctgg ccttcacctg gtggtgctgc aggctggccc tgggaatttg ggctttgggc 201720 caagggtgca gtctgtgtcc cgctaaaggt cacccctccc caaagtggag tggccagaag 201780 gatggcatcc tgtggtagaa gtcccactgt caagggtcct gtcctggcaa tttgttgccc 201840 aggctgcttc taagccatgg gttcacctcc aaagtggcgg ggtcttgagc cgaaggaaag 201900 gggaagacat catgtgttcc ctgattgact gagcatggcc tggctctgca tttggaggtg 201960 tgcggtgcac gaatggggac ccatcagaga aggcatgtgg ccctggggct ccaggatttg 202020 atttctggtg tgagctttta cagggggtct gtagtggcac gtagcattca ggtcagccta 202080 cttggtttgc tctgagcttg ttggtggtcc tggccctgcc cagtggtccc attgtggcat 202140 agagtcatgt gagggagctg tggcaaggag ggccaagggt tccccacatt catgatcgtt 202200 actgtttaca tggatcccat ctcttgagtc catggaggga cagcatgtgt gagccagcac 202260 cccctgccca ctttcctgca tggaggcgtg aggccgtatt tctatacgtg tcccccaccc 202320 ctccagatgg tgaccccaga ggaagacgtg cattgggtcc gctggcccca ggccagtgtc 202380 tctcagccat gtgctcaaca cctggtgagc tgaagctcag gcccttcctg gcatcctggt 202440 ctcctgcact gagctgtggt gagcacatct gggttcctct ggatacgtgt gcagggaggg 202500 ggatgcactg ggtcgggtca atgatgagaa ccttatattg ttctgaagag aggtgatgac 202560 ttaaaaatca tgctcaatag gattacgctg aggcccagcc taggtgagaa ttttggaaga 202620 ggatgctggg atcccaagtt ccccagcatg gccagtatat tttaggcagg agaccctgag 202680 gctctgaacg gcatctccgg ggggcacaac cctggctctg ggctcctctg ggaggcagcc 202740 caggttccct gtgcaggctt gggctctggt tccctgagcc cccattctcc ctcgtgtgtt 202800 tcagtgagct cgtcctccta ggtggggccc ccaggcattg accggcatag gtgagtggtc 202860 ctgctggggt catgggtcat cagcaggttg gagtcaccaa gggtcagcct ttgagacagg 202920 agggtttcca caggcagccg acctgaatcc acaccatgga gggatagatt ggtcctccaa 202980 gagggctgtt ttttttcgga atcagaccca aggaggatac cttccctgca gccctgcggg 203040 gatgacggtg gtccaggcag ggaagggttc cttcagtctc acgcaggtca gctcccagct 203100 gagtctcagt gcattggtct ggcctccagg actgaccagg ccacgtgagg ggggcaacag 203160 gggcttcggg atgcagtggg gtcacacagg atctctccat ccccagagaa aggtgggcat 203220 agaacccatg gattcgagct gcagagattc aagaatcgca cacgaattat tgccctgaat 203280 gggacccacc ctgttgagca atgtcccatc ccagggcacc tctttgagcc tgaagggggt 203340 ggtgctgttt ccctaggttt gggtcaaggc tgagctctgg ccagtgcctg gtggtgctgt 203400 agtcctgtca tggactcgtt agctttacgc caaggggtca gcccacgtcc tactggggat 203460 ctccccttcc ctgtggctgg aagtcacccc ttccccattg gcaagtgtca ggaagggtga 203520 cctcctgagg tggaagtcct gttgagggtc ttgtccctgg aatatgccac gcatgctgct 203580 tctgagccat ggggtcacct ccagggtagc gggtcttggg cccaaggaaa ggagaagtca 203640 ccatgtgtcc cccgattagc caagtgcggc cctgctctgt gtttaggagg tgtgtggggc 203700 atggatgggg acccaccaga gaaagcatgt ggcccaggga ccccaggttg caatttctag 203760 gacatgctgg gatagggcac ctgtgtgggt gtccacagtg cacagggata ggctatgtga 203820 cttgcaggtc tgcagcggca tctggcatcc aggccagcct ccttggtggg ccgtgaactg 203880 aatggtggcg ctggcctgtg cccagtatat ctggtatgac cctggggtcg tgtgggggag 203940 ccggcatggg cagtggaggt gcttatggga cctgcagtag gacacagtcg gggcttcttg 204000 cccaagccca gtgacccgct tgccctgtcc ttccagggtt cggtggctga gagagctttt 204060 gttgccctgt gtccgtgacg ggccagtgtt ctgcatgcat cccatcacat ggatccatgg 204120 agggtgagca tccctgggct gacacacccc accttctgcc cccatggagg ggtgaggttg 204180 tgttttcaca cctgtcttac tcctgtttcc ccagatgttg agcccagagg aagacttgca 204240 ctgggcccaa tggccccagg tcagcgtcca tcagccaggt gtccagcccc tggtgcactg 204300 aagatcgggc ccttcctggt gccctggtct cctgcattga gctgtggtga gcacatccgg 204360 atcctgctgg atgcgtgtgc ggggaagggg gtgccctggg ttgggtcaat gagaacctta 204420 tattgtcctg aagagaggtg ataacttaaa aatcatgctc aataatagga ttacgctgag 204480 gcccagtcta ggtgagaggt ttggaagagg atgctgggat tccgaggtcc ccaggagggc 204540 ccctgtattt ttggctggag acctggaggc cctgaagggc atcttgtggg tgcccaaccc 204600 tgtctctgcg ctcctccttg aggcagccca ggctccctgt gcaggcttgg tgtcagccct 204660 ccagttccct gggtttgagg cacatgggaa gctcctttct gagccccgtt ctcctcttgt 204720 gtctttcagt gagctcttcc acatggaaga cccctgtcat tgactggcat aggtgagtgg 204780 ctggcatcat gggccatgag ccaggccgcg tgaggtcgcc aagggtcagc cttcgggaaa 204840 gaagggtttc ctcagggagc caacctgaat ccccactggg aagatatggg ttctccagga 204900 gggcgacttc ctgggaaaca agaaccaagg aggtcccctt ccctgaagcc ctgcaggggt 204960 gacggtggtc caggcaggaa agggttcctt cagttccacc cagggcagct cccagctgag 205020 gctcggtgct tgcgtctgga cttaaggact gccctggcca tatgaggggt gccacagtgg 205080 ctctggggtg ccatggggtc acacaggcac tctctgtccc tggagaaagg tgggtgattg 205140 ggcccatgga gttgagctgt tgagatgcaa gttttgcacc tgacacatgg ccctgaatgg 205200 gacccaccct gttgagcaat gggccatccc atgggcctct tcgagcctga aggggggcgg 205260 tgctgtttca ctgggtttag gtcaaagctg acctctggcc gccacctggt ggtgctgcag 205320 tccagccctt ggactcgtgg gctttgggcc aagggggcag cctgcatccc actgaaagtc 205380 accccttccc tgtggctgga agttatccct tcctcatggg cgagtgttgg gaagggtggc 205440 ctcctgaagt gggaaggccc gctattgagg gtctgctcct ggcaatttgc tgcccatgct 205500 gcttctgagc catggagtca ccaccagtgt ggtggggtct tggacccgaa gaaaggagaa 205560 gacactgtgc cccccgatta gctgagtgtg gccaggctgt gtgtttgcga ggtgtgaagg 205620 gcatggatgg agactcacca gagaaagcat gtggccctgg ggccccaggt tgtggtttcc 205680 agtatgtgct tggatatggc atatgggtgg gtgcctacca tgcacaggga ctggctatgt 205740 gactgccagc tgtgcagcag catcaggcat acgggccagc ctccttggtt gaccatgaac 205800 tggttgctgg ccctggcctg tgcccagtag tcctggggtg accctggtgt catgtagggg 205860 agctggcatg tgtagtggag gtgctcgtgt ggtctgcagt agggagcagc cctggcttct 205920 agcctgagcc cagtgacctg cctgtcctgt cctttcaggg ttcagtggcg gagagagcat 205980 caggtggccc acgtctgtga tgggccagta ttccacatgg atctcatcac atgggtccat 206040 ggaaggcgag catccctgag ctggcacacc ccaccttctg ccagcatgga agggtgaggt 206100 tgcatttggc acctgtcctc ttcctgttcc tcgagatggt gaccccagag gaggacttgc 206160 attgggccca ctgtccccgg gccagtggcc atcagccggg tgcctagccc ctgttgcact 206220 gaagctcagg cccttcctgt tgccctggtc tcctgcattg agcttgggtg agcccatccg 206280 gttgccactg gatgcctaag cagggagggg ggttccctgg gttgggtcaa tgatgagaac 206340 cttacattgt tctgaagaga gatgatgact taaaaatcat gctcaatagg attacgctga 206400 ggcccagcct aggtgagaat tttggaagag gacgctggga tccctaggtc cctgacaggg 206460 ccactgtatt ttgggctgga gacctggagt ccttgaaggg catctggagg gggcccaaac 206520 ctgtctctac gttcctccat gaggcagtcc aggctccctg tgcgagcttc gtgtcggtgc 206580 tcagattccc cttggtggtg catgtgggtg gctcatccct gagcccctgt tctccccttg 206640 tgtctttcag tgaactcgtt tgcccaggag gacccctggc cttgagcagc ataggtcagt 206700 ggatcctact ggggtcatgg gccatggacc aggccacgtg gggtcactga gggtcagcta 206760 tcaggacagg agggattcct cagggagaca acctgaatcc ccactggtga gggattggtt 206820 ctccagaagg gccgcctcct tgggaatctg acccaaggag gacaccttcc ctgaagtgct 206880 acaggagtga cattggtcca ggcaggaaag ggttccatta gtcccatgca ggtcagctcc 206940 cagctgagac ttggtgctag ggtctggcct tgaggactgc ccaagccaca tgaaggtggc 207000 cccaggctgt gatttttggt gcgtgcttgg agagggagtc tgggcaccct ccctgcacag 207060 gggcaggctg tgcgtctgcc aggtctacag tggcgcctag cttcagagca agcttccttg 207120 gttggcctta gctggttggt ggccctggct cctacccagg ggtcacaatg cagcccagga 207180 agtgcaggga agccggcttg gacagtggag gtgctccagg ggcctgcggt agggcacagc 207240 ctcggcatct tgcctgagcc tagttactcg cctgtcctgt ccttccaggg tttggtggtg 207300 gggagataca agggttcccc aggtccataa ctgtcctcgt ttcacatgga tcccatcaca 207360 tgagtccacg gatgtagagc atgtgtagcc agcagcccct ccccgctttc ctgcatggaa 207420 tcttaaggcc ctatttggac acctttcccc gtccctccag atggtgagca cagaggaaga 207480 attgcgttag gccctttggc cccggaccag tgtctgccag ccacgtgctc agcctcccgt 207540 gcgctaaagc tcaggtcctt cctgtcatcc tggtatcctg cactgaggtg tggtgagtcc 207600 atccaggtcc ctctggatgt gtgagtgggg atgggggtgt cctgggttgg gtcgatgatg 207660 agaaccttat attgtcctga agagaggtga tgacttaaaa atcatgctca ataggattac 207720 gctgaggccc aacttaggtg agaattttga aagaggatgc tgggaatcac aaggtccccg 207780 gcaggaccac tgtattttag gcgggagacc tcgaggccct gaagggcata tcatggaggg 207840 gtacccaacc cagtctgtgc tcctccatta ggcacaccag gcttcctgtg tgggcttggt 207900 gtctgcactc agcttccccg ggggtgggac acattggtgg ctccttcctg agtcgcattc 207960 tcctctgtgt ctttcagtga gctcttcccc ccagcaggcc ccctgggatt gactggcaaa 208020 ggtgagtgga tactgctcgt gtcatgggct gtgagccaag ctgcgtgggg tccccaaggg 208080 tcagccctcg ggtcacctgg gtttcctcag gagctgatct gaatcctgac tggggatgtg 208140 ttctccagga gggcagcttc cttgggaatc tgacacaagg aggaggcctt ctctggagcc 208200 ctgcaggggt ggtggtggtc caggcaggaa agggtttcct cagctccaca caggacagtg 208260 gagctgggca gtgctcagct cagacttggt gctcaggtca ggcctctagg atggccaggc 208320 cacatgacgg gggccacaag ggctccaggg caccacagac atctcatggg ggctctccaa 208380 ccctggagaa gggtgggcaa tttggcccat tgggtcgggt catggagctt caaggattgc 208440 accaaaccca tatccctcaa tgggaccgac cctattaagc aatgggccat cccagtggca 208500 cctctttgag ccatgtggtg ggtggcgctg tttctctgag gttgggtcaa gactagctcc 208560 ggccagtgcc tgatggtggt gcagtccagt cctgggactc gtgggctttg ggccaagggt 208620 gcagcccgtg tcctactggg gatcacccct tccttatgag ggagtggtgg gaagggtatc 208680 ctcctgaggt aggaaggccc gctgtggaag gaactttcct ggaaatttgc agtccagact 208740 gcttctgagc catgaggtca tctccggggt ggcggggtct tgggcccaag gaaaggagaa 208800 gacaccatat gtctcccgat tggttgagta tggctccact ctgtgtgtgg gaggtgttgt 208860 gtggggcatg gattgggacc caccagagaa agctcgtggc actggaaccc caagctgcaa 208920 tttccagtgc accttgggaa ggggactggg tgctcaccct ccatgcacag ggcaggctgt 208980 gcagctgcca agttggcagt ggtgcgtggc atccgggcca gcgtccttgg ttcgctgtga 209040 gctggttggt gtccttgacg cctgcccagg ggtcccagtg ctgcttgggg tcatgagggg 209100 agccagcgtg ggcaagggag gcctgcagta gggcacagcc cgggggtctt gcctgagccc 209160 aggatcctgc cggccctgtc cttccatggt tcggtggctg ggagggcaaa gggtccccca 209220 cgtctgagac acatcagtgt ttcacatgga tctcatcaca tgggtccata gagagagagc 209280 aagcgtgagc tgacaccccc cacccccttc cctgtataga ggtctgagcc cctggttgga 209340 cacatgtctt cctcctgtcc ccccagatgg tgtctgtgga ggaagacttg ccattgggtt 209400 gctggcccca ggccagtggt tgtcatccag gtgcccagcc ttggtgcact gaagctcagg 209460 cccttcctgg tgctctggtc tcctgcactg agctgtggtg agcacatccg ggtcccactg 209520 gatgggtgtg tgtggtgggg ggtgccctgg gttgggtcga tgatgagaac cttatattgt 209580 ctgaagagag gtgatgactt aaaaatcatg ctcaatagga ttacgctgag gcccagccta 209640 ggtgagaatt ttggaagagg atgctgggaa ttacaagttc cctgtgaagt ccactgtatt 209700 ttgagctaga gacctggagg ctctgagggc atctggaggg tgcccaaccc tgtctctgca 209760 ctcctccatg aggcagccca ggctcactct gtgggcttgg tgtcggcgct cctgttaccc 209820 aagggtgggg tactttggca tctcctccct gagcccccat tctcccctgt gtctttcagt 209880 gacctctttt gcccggcaga ccccctggca ttgaccagca taggtgagtg gatcctgctg 209940 gggtcatggg tcatgagcca ggctgtgtgg ggttgccgag catcagcctt tggctgcaag 210000 ggtttcctca ggaactgacc cgaatgccca cctgggatgg gttctccagg agggcagctt 210060 ccttaggaat cggacccaag gaggatacct tccatgaagc cctgcagggg ttgtggtggt 210120 ccaggcagta aagggtttcc tcagccccat gcagggcagc acccagctga aactcggtgc 210180 ttaagtcagg cctctaggat ggcccgtcca catgagggga accacaaggg cactggggcg 210240 ccaagggggt cttatggggg ctctccgacc ttggagaggt atgtgtgatt cggcccatga 210300 ggtcaggttt tggattttca aggatctctc caaacccatg gccctgaatg ggaccgaccc 210360 tattaagcta tgggccatcc cagtggtgcc tctttgagcc aagtgtgggg tggcactgtt 210420 tccatgaggt tgggtcaaga ctagctctgg tgaccccatg atggtgctgc agtctggccc 210480 tgggactcgt gggctttggg ccaagggtat agcccatgtc ccaccagggg ccacaccttc 210540 cttgtgggca agtggcggac agggtgtcct cctgaggtga gaaggcctgc tgtggaagga 210600 cctgtccagg ctgcttccaa gctatggggt cacctacagg gtggtggggt caaggaaagg 210660 agaagacacc atgtgtctcc cgattggctg agtgtggccc cactctgtgt gtgggaggtg 210720 ttgtgtgagg catggatggg gacatatcag agaacacacg aggccctggg tccccaggct 210780 gcaatttccg gtgtggtgtg gagcagggcc tgggtgcttg ccctccacac acaggggcag 210840 gctgtgctac tgccagattg gcagcagtac gtggcatcca ggccagcctc cttggttggc 210900 cgtgagacgg taggtggccc tggctgacac ccaggggcca gtacagccct ggggtcatgt 210960 gaggcaactg gagtgggtag tggaggtgct caaggtgcct gcagtagggc atagccaggg 211020 cgtcttgcct gagcccagtg acctacctgc cctgtccttc cagggttcag tggtgcagag 211080 ggccaaagtt cccctgtgtc catgacacat cagtgtttca catggatccc atcacatggg 211140 tccatggtgg gagagcaatc gtgagctagc atcccccacc cccttcctgc atggaggcgt 211200 gaggttccat ttggacacat gtccacctcc tgtcccccag atagtgagac tggaagaaaa 211260 ctttcattgg gcccgctgtc ccggggtgag tggtcatcag tcaggtgccc agcccttggt 211320 gtggtgaagc tcaggctctt cctggcgccc tggtctcctg cacggagctg cggtgagcac 211380 atccgggtcc cgatggatgc atgcgtgggg atggagggcg tgccctgagt tgggtcaatg 211440 atgagaacct tatattgtcc tgaagagagg tgatgactta aaaatcatgc tcaataggat 211500 tacgctgagg cccagcttag gtgagaattc tggaagagga tgctgagatc cgaagtcccc 211560 tggaagggcc actgtatttt gggctggagt ccttgaggcc ctgaaggaca ccttcggggt 211620 gcccaaccca gtctctgcac tcctctgtgt ggcagccaag gctccttgtg caggcttggt 211680 gttggcattc tggttccctg ggggtggagc acatcgacgg ctcctccctg agcccccgtt 211740 cttctctgtg tctttcagtg agctcttcta cccaggcggg cccctgccct tgagcggcat 211800 aggtgagtgg atcttgctgg ggtcacgggc caagagccag gccacggggg gtcgctgagg 211860 gtcacctttc aggccacgag ggtttcctta gggagctgac ctgaatcccc accagagatg 211920 gatggtttct ccggaagggc agcttccttg ttaattgatc ccaagaagga cgccttccct 211980 gaaaccctgc aggggtaatg gaggcccagg cagcagagag ttccttcaac ccaatacagt 212040 gcagcagctt gttgccttga tgctccccct ccctggagaa aggtgggcat agggcccgtg 212100 gagttgagtt gcagagattt aaggatcgca caggacttat tgacctaaat gggactgacc 212160 ctgttgagca acgtgcactt ggtgcatggg tcaggtgtgg agcactgccc aggccacatg 212220 aggggtccac tgggtctctg ggggccacgg gtgttatgca ggagctctcc gtccccaagg 212280 cttgcagggg ggtaggatgt cggtgatcga gcttatgcag tcaggccgtg aagattcaag 212340 gattgggccc aacccatggc cctgatggga ccgaccctgt tgagcaatgg gctatcccac 212400 tggtgcctcc ttgagcctgg tgggggcagt gcggcctcag tgggcttgga tcaaggctga 212460 gctctggcca gcacctggtg tttggccctg ggaatcgtgg gctttgggcc aagggttcag 212520 cctgtgtccc actggagttc atccctaccg gaagtggagt ggatggaagg gtggcatcct 212580 gtggtggaag acccaccgtt aagggtcctg tcctggcaat ttgatgccca ggctacttct 212640 gagccatgga gtcacctcca gggtagcagg gtcttgagcc aaaggaaagt tgaggacatc 212700 atgtgtcctc tgattggccg agcgtggccc agctctgtgt ttaggaggtg tgcggtgcat 212760 gaatggggac ccaccagaga aggcatgtgg ccctggggcc ccaggatgtg atttctggtg 212820 tgtgcttata aagggtgcct ggatgggttc atttaatgcc caggggcagg ccatgtgact 212880 gccaggtctg cagtggtacg tggcatccag gccagcctcc ttgatttgct gtgagctatt 212940 tggtgcccat ggccctgccc agtggtcctg atgcagccca gattcgagca ggggatttgg 213000 cgtgggcagt ggaggtgctc cagggtcctg cactagggtg cagcctgggc gttttgctcg 213060 aaccctgtga ccctcctgcc ccgtccttcc agggttcagt ggccaagggt tcctcgcgta 213120 aatgaccatc actgttttac atggatctca tctcatgagt ccatggaggg agagcatgtg 213180 tgagccagca ccccctgccc actttcctgc atggaggcat gaggccttgt ttggacacct 213240 gtcccccacc cttccagatg gtgaccccag aggaagactt gcgttgggcc cactggctct 213300 gggctcagcc cctggtgagc tgaagctcag gcccttcctg gcaccctggt ctgctgcact 213360 gagctgcggt gagcctatct gggtcccact ggatgcatgg gttgcggggc agtggagggt 213420 gatgccctgg gttgggtcga tgatgagaac cttatattgt cctgaagaga ggtgatgact 213480 taaaaatcat gctcaatagg attacgctga ggcccagcct aggtgagaat tttggaagaa 213540 ggtgctggga tccggagttc cctggaatga ccaatgtatt ttgggctgga gaccttgagg 213600 ccctgaacag cagcatctcg tgggggccca accccttctc cgtgctcctc tgtgaggcag 213660 cccaggctcc ctgtgtgggc ttggtgttag tgctccggtt ctgtgaaccc ccattctccc 213720 cttgtgtctt tcagtgagct cttccaccca ggtgcaaccc cctggcattg accagcatag 213780 gtgagtggtc ccgctggggt catgggtcat cagtcatgca gtgtggggtc accaagagtc 213840 agcctttgag acaggagggt ttccacaggc agctgacctg aatccacacc atggaagggt 213900 aggttggtcc tccaagaggg ctgttttttt gggaatcgga cccaaggatg atatctttcc 213960 tgcagccctg cagtgatgac ggtggtccag gcaggaaaag tttccttcaa tctcatgcag 214020 ggcagctccc agctgagtct cagtgcactg gtctggcctc gaggactgac caggccacgt 214080 gaggggggcc acaggggctt tgggatgcca tggggtcaca caagagctcc ccatccctgg 214140 agaaaggtgg gcatagagcc catggagttg agctgcagat atttaaggat cacacaggat 214200 ttatagccct gaatgggacc gaccctgttg agcaatgtgc catccatcct atggtacctc 214260 tttgggcctg gatggggtgt tgctgtttcc ctaggttttg gtcaaggctg agctctggcc 214320 agtgcctggt ggtgctacag tccagccacg gacttgttag ctttaggcca agggatcagt 214380 ccacgtcctg ctggggatct ccccttccct gtggctggaa gtcacccctt ccccattggc 214440 aagtgtgagg aagggtggcc tcctgaggtg gaaggcctgc tgttgagggt cttgtccctg 214500 gaatatgcca cccacactgc ttctgagcca tagggtcacc tccaggatag tgggtattgg 214560 gccaaaggaa agaagtcacc atgtgtcccc tgattagcca agtgtggccc tgctctgtgt 214620 ttaggaggtg tgtggggcat ggatggggac ccaccagaga aagcatgtgg ccctgggact 214680 ccaggttgtg atttccagtt catgctggga tagggcacct ggatgggtgc ccacaatgca 214740 ccggggcagg ctatgtgact gccagctttg cagcggcatc tggcatccgg gccagcctcc 214800 ttggttggcc atgaactggt tggtggccct ggcctgtgcc cagtagctct gtcgtaatcc 214860 tggggtcatg cgagggagcc ggcatgggca gtggaggtgc tcgtgggacc tgcggtagga 214920 cacagccagg tcttcttgcc cgagcccagt gacccacctg ccctgtcctt ccagggttca 214980 gtggttgaga gtacagggtg acttgtgtct gtgacaagcc agtgttctgc atggatccca 215040 tcacgtggat ccatggacgg caagcatccc tgagccgcca caccccacct tctgcctcca 215100 tggaggggtg aggttgtgtg tggacgcctg tcctactcct gtttccccag gtattgagcc 215160 tggaggaaga cttgaattgg tcccaatggt cccaggccag catccatcag ctaggtgctg 215220 agcccctggt gcactgaaga ttgggcactt cctggcaccc tggtgtgctg caccgagctg 215280 tgatgagcac atccgggtcc tgctggatgc atgcgccggg aaggacgtgc cctgagttgg 215340 gtcgatgatg agaaccttat attatcctga agagaggtga tgacttaaaa atcatgctca 215400 ataggattac gctgaggccc agtctaggtg agagttttgg aagaggatgc tgggatcctg 215460 aggtcccctg gtagagccaa ttgtattttg ggctggagac ctggaagccc tgaagggcat 215520 ctgggaggcc caaccctgtc tctgtgctcc tccatgaggc agccctggct ccccatgtag 215580 gcttggtgat ggccttcctg ttccctgggg gtggggcaca tgggtagctc ctccctgacc 215640 cccattctct cctgtgtctt tcagtgagct cttccccaca ggtgggcccc ctggcattga 215700 ctagcatcgg tgagtggatc ctgctggggt cgtgggccgt gcaccaggct gcatggggtc 215760 accaagtatt agccttcagg acaggagggt ttcctcaggg agtcgacctt aatcctcacc 215820 tgtggagaga tgggtttgtc ctctaggagg gcagcttcct gggaaatcag acccaagacg 215880 atgccttccc tgaagccctg caggggtgac ggtggtccag tctggaaagg gttccttcag 215940 tctcatgcag ggcagctccc agctgacact tggtgtgaga gtctgtcctt gaggactgcc 216000 caggacaaat gagtgggaca acagaggctc ccggatacca cagggatcac tcaggggctc 216060 tccgtccctg gaaatgggtg ggcgatcggg cccatggggt ggggctgcgg agattcaagg 216120 atcgtgccct gctcatggcc ctgaatgcaa atgaccctgt tgagcaatgg gtcacaccag 216180 tagctccttt ttgagcctgg tgggtggcgg ctcagcttca actggttggg tcaaggctga 216240 gccatgactg gtgctttgtg gtgccgcagg ccaaccctgg gactcatggg ctttgggtca 216300 agggtgcagc ccgcctgctg ctgggggtca ccccttcttc gaggtcagtg gcgggaaggg 216360 tcacgtcccg aggttggaaa gccccctcat gagggacctg tcctgggaat ttgttgccca 216420 ggctgcttct gagccatgtg gtcacttccg ggtggcgggg tcttgggccc aaggaaagga 216480 gagggcacca tgtggctcct gattggctca gtgtggccca gctctgtgtt tgacaggggt 216540 ctggggtgtg gatgaggacc caccagacaa agcacgtggc cctgggccca ggctgtgatt 216600 tctggtgcgt gcttggagaa ggatcctggg caggcattct ctccaaacag gggcaggttg 216660 tgggactgcc agattggcag cagtgcctgg catccaggcc agcatccttg gttggctgtg 216720 agctggttgg tgaccttgga ccctgcccag ggtttccgtt gtggtccaga gtcatgcagt 216780 ggggccagtg tgagcagtgg aggtgctcca ggggcctgct gtatggcaca gccagggcat 216840 cttacccaag ccctcctgca ctggtctcct gcactgagct gtggtgagcc catctgggtt 216900 cctgtgatgc ctgtgcgggg agggggttgc cctgggttgg gtcgatgatg agaaacttat 216960 attgtctgaa gagaggtgat gacttaaaaa tcatgctcaa taggattacg ctgaggccca 217020 gcctaggtga gaattttgga agaggatgct gggaattatg agttccctgg cagaaccact 217080 gtattttggg ctggagacct ggaggctctg agggcatctg gagggtgccc aaccctgtct 217140 ctgcgctcct ccgtgaggca gcccaggctc actatgtggg cttggtgttg gcactcctgt 217200 tacccggggg tggggcattt tggcatctcc tttctgagcc cccaatctcc cctgtgtctt 217260 tcagtgagct cttctgccca gcagcctccc tggcagtgac cagcataggt gagtggatcc 217320 tgctggggta atggcccatg agccaggctg tgtggggtca ccaagcatca gccttcagcc 217380 ataagagttt cctcaggagc tgacccgaat gcccacctgg gatgggttct ccagaagagt 217440 ggcttccttg gaaatcatac ccaaggaaga taccttccct gaagccctgc aggggttgca 217500 gtggtccagg cagtaaaggg ttttctcaac ctcatgcagg gcagtgcccc actaagactc 217560 agtgctctgg tcaggccttt aggatggcca ggccacatga gaggggccac aagggctctg 217620 gggcaccaag gggttcttgc aggggctctt caaccttgga gaggtgtgtg taattcagcc 217680 catgaggtca ggctgtggat tttcaaggat tgcaccaaac ccatggccct gaatgggaca 217740 aaccctaata agttatgggc catcccagtg gtgcctcttt gagccaagtg tggggtggca 217800 ctgtttccta agggtgagtc aagactagct ctggctggca cctgatggtg gtgcaatcct 217860 gccctgggat tggtgggctt tgggacatgg gtacagccca tgtcccattg gggtcacccc 217920 ttcattgtgg acaggtggcg ggaagcatgt cctcctgagg tgggaaggcc tgctgtggaa 217980 gaccctgtct cagaaatttg ctgtcttggc tgcttctgag ctatggcgtc acctctgtgg 218040 tggcgggagt ctcgggtgaa tggatcctgc tggggtcatg ggccatgagc caggccgggg 218100 tggggtccct gagcgtcacc tttcgggtca tgagggtttc ctaagggagc cgacctgaat 218160 ccccaccagg gatgaatggt ttctctggga agcaggtttc cttggaaatc agtcccaaga 218220 aggacacctt ccctgaaacc ttgcaggggt aacagaggtc caggcaagag agggttcttt 218280 caacccaacg cagtgcagat cctagctgag acttggtgca caggtgagtc ctggaggact 218340 gcccaggcca catgagggca tccacagggt ctccgtggcc aggagtctta tacgggagcc 218400 ctctgtcccc gaggcttgca gaggggttgg gtgtgggtga tctggcttac ggagtcaggc 218460 cgtgaacatt caagggtcgg gaaccaccca tggccctgaa tgggaccgac cctgttgagc 218520 aatggccatc ctggtggtgg caccttgagc ctggtggggg tggcgctgcc tcagtggggt 218580 tgggtcaagg ctgagctctg cctgtcacct tgtggttggc cctgggaatc atgggctttg 218640 ggccaagggt gcagcctgcg tcccgcttga ggtcactcct acctgaagtg gagtggccgg 218700 aagggtggca tcctgtggtg ggagacccac ggtcaaggat cctgtgctgg caatttgctg 218760 cgcagcctgg ttctgagtca tggggtcacc tccagggtga cagggtcttt gtcaaaggga 218820 aggagaggac attatgtggc ccctgattgg ccaagcatgg cccagctctg tgtttgggag 218880 gtatgcggtg cctgaatggg gacccaccag agaaggcaca tggccctggg gccccaggat 218940 ggtatttctg gtgtgagctt ataaagggtg catggatggg tgcattccat gcccagtggc 219000 gggttatgtg actgccaggt ctgcagtggc acatggggtc cgggccagcc tccttggttt 219060 gccatgagct ggttggtggc ccaggccctg cctagtggtc tcattgcagc ccagagtcat 219120 gtgggggagc tggcgtgggc agtcgaggtg ctccagggtc ctacagtagg gtgcagcctg 219180 ggcgtcttgc tggaatccca tgacccacct gccctatcct tccagggttg agtggcaggg 219240 agggccaagg gttcctcgtg tgcatgactg tcactgtttt acatggatct catctcatga 219300 gtccatggtg ggagagcatg tgtgagccag cacaccctac ccactttgcc ctatggaggc 219360 acaaggccct gtttggacac ctgtccccca cccctccaga tgctgaccct ggaggaagaa 219420 ttgcactggg cccactggcc ccgggaaaat gtccctcagc caggtgctta gcccctggta 219480 atctgaagct caggcccttc ctgatgccct ggtctcctgc actgagctgt ggtgagcaca 219540 tctgggtccc aatggatgca tgcatgcgtt gtggggtggt ggtgtcctgg gttgggtcga 219600 tgatgagaac cttatatgtt ctgaagagag gtgatgactt aaaaatcatg ctcaatagga 219660 ttacgctgag gcccagccta ggtgagaatt ttggaagagg atgctgggat ttctaggtcc 219720 ctgtcatggg cactgtattt tggactggag acctccgggc cctgaacagc atctcggggg 219780 ggactctacc ctgtctccac attacatgtg aggcagccca ggctcccttt gtgggcttgg 219840 tgtctgcact ctggttccct gtggtagggc agcttgctgg gtccttcctg agcccctgtt 219900 ctccctttgt gtcttctgtc tttcagtgag ctcttcagcc caggtgggct ccctgacact 219960 gatgcgcata ggtgagtgga ttctgctggc atcatgggcc atgagccaag ctgcgtaggg 220020 tcaccaaagg tcactcttta ggccacgtgg gtttcctcag ggagccgacc tgaatcccca 220080 ccaggttggg acagtttctc caggaggctg gcttccttgg gaatcagacc caagacaatg 220140 ccttccctga agccttacag gggtaacagt tgtccagaca ggaaagggtc ccctcagtcc 220200 cattgaaggc agctcccagc tgagactcag tgtgcgagtc tggcctcaag gatggcccag 220260 gccacatgaa ggaggccaca ggggctctgg ggtgccacag gggtcacacg agagctctct 220320 ttccctggag tggggtgctc gaatgagccc atggggtcag gctgcagaga ttcaaggatc 220380 gcatcccaac cgtggcccta aatgcgaccg accatgttga gtaatgggcc atctcagtgg 220440 ggcctctttg agcctggtgg ggggcggggc tgtttccctg ggtttgggtc aaggctgagc 220500 tctggccagc gcctggtgat gctgcaggcc agcccaggtt cttgtgggcg ttggtccatt 220560 cggcagccct gtcctcctgg aggtcacccc ttgcctattg gtgattggct ggatcctgag 220620 gtggaaagac ctgctgttga tggtcctgtc ccaggaattt accacccagg ctgcttctga 220680 gccatggggt cacctccagg gtggcggagt cttggggcta agaaaaaaga ggacactatg 220740 tagcccacgg ttggccaagg gtggcctgac tctgtgtttg ggacatgtgc ggggcatgga 220800 tagggacccg ccagagaaag cacgtggccc ggggactcca ggcttcgatt tcaggtgtgg 220860 cttgcaaata gcacctaggc aggtgcccac cacgccctgg ggcaggctat gcaacttcca 220920 tctccacagt ggcgcatggc ttctgggcca ttctccttgg ttggccatga gctgattggt 220980 tcccctggcc tgtgccctgt ggtcccggag tggctctggg atcgtgtggg gcagccagca 221040 tggacagtgg agatgctatc aaggccttca gtagggtgca gcccaggttt cttgcctgaa 221100 cccagtgacc cacctaccct gtgttttcag ggtttgctga cagggaaggc caaacgtgcc 221160 ccacgtccat gctaggtcag tgttcctcat ggaccccatc acatgggtat cccttacccc 221220 ttccccacat ggaagtatga ggctctgttt ggacacatgt cctcttcctg tccccccaga 221280 tggtgagcct ggaggaagac ttgcattggg cccaatggac ccaggccagt ggccatcagc 221340 caggtgccca ccctggtgtg ctgaagcgcg ggacctacct gttgtcctgg tttcctacac 221400 tgagctgagg tgagcacatc tgggtccctc tggatgcatg catggggcgg ggggtgccct 221460 ggtttgggtc aatgatgaga accttatatt atcctgaaga gaggtgatga cttaaaaatc 221520 atgctcaata ggattacgct gaggcccagc ctaggtgaga atttggaaga ggatgctggg 221580 atcccaaagt cccagtaggg gactttattt atttattttg ggctggagcc ctggaggccc 221640 tgaagggcat ctggggggcc cagccctgtc tctgtgctcc tccgtgaggc agcccagcct 221700 ccctgtgtgg gcttgctgtt ggtggtccag ttccttgggg cggggcacgt ggacagctcc 221760 tccttgagcc cccctgctcc acttgtgtct ttcagtgagc tcttcaaccc aggcggggca 221820 ccctggcatt caccagcata ggtgagtgga tcctgctgcc atcgtgggcc atgggccagg 221880 ctgggtagag tcactgaggg tcagccttcg ggacaggaga gtttcctcag ggagcgaacc 221940 tgaatcccca ccagggaggg ataggttggt cctccagaag ggtggcttcc tgagaaatcg 222000 gacccaaggg ggacgccttc cctggagccc tgcagtgatg acggtggtcc aggcaggaga 222060 gggttccttc agtctcacac atagtagctc ccagctgagt ctaggtgttc gagtctggcc 222120 ttgaggactg cccaggccac ctgaggggcc aacagggact ctgggacacc atgggggtca 222180 cataggagct ctccattcat ggagaaagat ggatgatagg gcccatggag tcgagctgtg 222240 gagatttaag gattgcgccc aatgtatggc cctgaatggg acagaccctg ttgagtaatg 222300 agccattcta tgggcctcat cgagccttga gcggggcggt gctgtttccc tatgtttgag 222360 tcaaggctgg actctggccg gtgcctggtg gtgctgaggt ctggccatgg actcgttggc 222420 tttgggccaa ggggtcagcc tgctccccct ggaagtcccc ccttccccgt ggctggaagt 222480 catcccttcc caaggggcaa gtgtcgggaa tggttgcctc ctgaggttgc aaggcctgct 222540 atctagggtc ttgtctttgg aatatgctgc ccatgctgct tctgagtcat ggggtcacct 222600 ccagggtagc ggatcttggg cccagggaca gaagatgccg tgtgtcccct gattagctga 222660 ttgtagccct gctctgtgtt caggaggtgt gtggggcatg gatgcagacc caccagagaa 222720 aactgtggcc cttagacccc aggttgcaat ttccattatg tgctgggata gggcatctgg 222780 gtgggcaccc actatgcaca gagataggct atgtgactgc cagggctgta gcggcatctg 222840 acatctaggc cagcttcctt ggtttcctgc gaatgagttg gtggccctgg cctgtgccta 222900 gtagttctgg ggtgaccccg ggtcgtgtgg gggagccagc aggggcccag tgaccagcct 222960 gccctgtcct tccagagttc tgtggctaag agagcactgg gtaccctgtg tccgtgatgg 223020 gccagtgttc cgcatgcaaa cgatcacatg ggtccatgga gggcaagcat acttgaactg 223080 ccacacccca ccttctgctc acatacagga gtgaggttgt gtttggacag ctgtcctact 223140 cctgttcccc tagactgtga aatgggagga agaattgtgt tgggcccaat ggccctgggc 223200 cagtatccgt cagcctggtg tccagcccct ggtgtgctga agctcatgcc cttcctggtg 223260 ccctagtttc ctgcactgag cttggtgagc ccatttgggt actgctggat gcatgggtgg 223320 ggagggaggt gccctgggtt gggtcgatga tgagaacctt atattgtcct gaagagaggt 223380 gatgacttaa aaatcattct caaaaggatt atgctgaggc ccaccctagg tgacaatttt 223440 ggaagaggac actggaaatc aatgaggtcc ctggcagggc cactataatt tggggtggag 223500 acctggaagc cctgcagggc acctcgtggg ggcccaaccc tgtctcttca ctcccctgtg 223560 aggcagccca agctccctct gtaggcttgg tgtcggcact ctgctttcct ggaggcgggg 223620 cattttggct gctccttcct gagcccctgt tctcccctgt gtctttcagt gagctctttt 223680 gcccagaaga ctccctggca ttgatcggca taggtgagtg tctcctgctt gggtcatggg 223740 ccatgagcca gaccataggg ttgccgaggg tcagcatttg agccatgagg gtttcctcag 223800 gaggcgacct gaatccccac ctgggatggg ttctccagga gggcagcttc cttgtgaatc 223860 tgagccaagt aagatgcctt ctctgaagcc ctgcaggggt gccagttgtg caggcaagaa 223920 agggttccct cagccccagg cagggcagcg cccagcagag actcggtggt tgggttaggc 223980 ctctaggatg accaggccac atgagggggg ccacaagggc tctggggcac aacaggggct 224040 tcgcagggtc tctgcgaccc caaagagtgg tgggcgattc ggcccatggg atcgggcccc 224100 agattcaaag atcacaccac acccatggcc ctgaatggaa ccgaccctgt taagcattgg 224160 ggcatcccag gggtgccact ttgaacctgg tgtggggtgc cgctgtttgc ctgaggttgg 224220 gtcgagacta gctccggcca gcacctgatg gtggtgcagt ccggccctga gattagtggg 224280 ctgtgggccc agggtgcagc ctgtgtcccg ctgggggtca cctcttcctt gtgggcgagt 224340 ggtggaaggg catcctcctg aagtgggaag gcccgctgtg gaaggaactg tcctggaaat 224400 ttgccatcca ggctgcttct gagccatggg gtcgcctcca gagtggcagg gtcttgggcc 224460 caaggaaagg agaggacact gtgtttccct caattagctg agtgtggccc tgctctctgt 224520 gtgggaggtg ttgtgtgggg catggatagg gacccaccag agacaacaca tggccctcgg 224580 gccccaggct gcaatttctc agtgcatgct tggagacggt cctgggcctc ctccatgccc 224640 agggtcaggc tgtgcaactg tcaggttagc ggcggcatgt ggtgtctggg cctgtctact 224700 tcgttgtccg tgagctgctg gtggccctag ccctttccca ggggttcagg tgcagccctg 224760 gggttgtgtg ggacagccag tgtgggcagt ggagctgctc tggaggcctg ctttagggtg 224820 cagcctgggt gtcttgcccg agtgtagtga cccgcctgcc gtgtcctcac ggggttccct 224880 agcaggaagg gccaagggtc ccctgtgtct gtgacacgtg agtgtttccc atgggtccca 224940 tcaaatgggt ccacggaggg agagcatgag tgaactggta ccccccaccc ccaccctctt 225000 ccccacctgg aggcatgagc ccctggttgg acatatgtcc tcctcctgta cccccagatg 225060 gcagcgctgg aggaggactt gtactggggc cgctggcccc acatcagtgt ccgtcatccc 225120 ggcgtccagc ccctggtgtg ctgaagctca ggcccttcct tgtgccctag tctcctgcac 225180 tgagcttggt gagcccattc ggatactgct ggatgcatgg gtcgggaggg aggtgccctg 225240 ggttgggtcg atgatgagaa ccttatattg tcctgaagag aggtgatgac ttaaaaatca 225300 ttctcaaaag gattatgctg aggcccggcc taggttagaa ttttggaaga ggatgctggg 225360 atcctgaggt ccccaggaga gcccctttat ttttggctgg agacctggag gccctgaagg 225420 gtatctgggg ggcccagccc tgtccctata ctcctctgtg aggcagccca ggctctctgt 225480 gtgggcttgg tgttggcact ctggttttct gggggcggtt caggttgctg gttccttctg 225540 aaccattgtt ctccccttga ttctttcagt gagctcttct gctcaggcgg gtcccctggc 225600 attgaccagc ataggtaagt ggatcctgct gggttcatgg gccatgagcc agaccacatg 225660 gagtgactga gggtcagcct tcaggacagg aagatttcct cggggagcca acctgaatcc 225720 ccaccgtgga gggatgtgtt agtcctccag gagggtggct tcctagggaa tctgacccca 225780 ggaggacacc tttgctgaag ccctgcaggg gtgatggtgg tccaggctgg aaagttttcc 225840 ttcagtctca tgtggggcag ctccctgctg acattccgtg cctgcgtctg accttgagga 225900 ctgcccgggc cacatgagtg gggcaacaag ggctccaggg tgccacgggg attatgagtg 225960 gggctctcca tccccggaga gaggtgggca atcaggccca tgtggtcagg cttgtagggt 226020 tcggtggtgg ggagagccaa ggtttccctg ggtccattac cgtcactgtt tcacctggat 226080 cccatcacat gggtccatgg agggagagca tgtgtgaaca ggcacccctt gctccctttc 226140 ccacatgagc ccctggttgg acatatgtcc tcctcctgtc cccccagatg gtggccctgg 226200 aggaggactt gtattggggc cactggcccc acgtcagtgt tcgtcagcct ggcatccagc 226260 ccctggtgtg ctgaagctca ggcccttcct gttgccctag tctcctgcac tgagcttggt 226320 gagtccattc ggggactgct ggatgcatgg gcgggtaggg aggtgccctg ggttgggtcg 226380 atgatgagaa ccttatattg tcctgaagag aggtgatgac ttaaaaatca ttctcaaaag 226440 gattatgctg aggcccggcc taggttagaa ttttggaaga ggattctcgg atcctgagat 226500 ccccagccag gccactgaat ttttggctgg agtccttgag gccctgaagg gtgtctgagg 226560 gctgctgaaa cctgtctctg tgcttgtccg tgaggcaacc cacattcgct gtgtggactt 226620 ggtgttggcc ttcccgttct ccggggatgg gacatactgt cagcttgtcc ctgagtaccc 226680 gttctcccct gtgtctttca gtgagctctt ctgcccaggt ggtccccctg gtcttgatgg 226740 gcataggtga gtacatcctg ctggtgtcct ggtccatgag ccagggtgcg tacggttgcc 226800 ggaggtcacc tttaggccat gtgggtttcc tcagggagct gacctgaatc cccactggga 226860 gggatggttt ctccaggagg atgtcttcca tagaaactgg ttccaagaag gatgccttcc 226920 ctgaagctgt gcaggggtga cgatggtcca ggcaggaaag ggtccattca acccaatgca 226980 gtacagcttc tagctgagac tcggtgcacg ggtgagggct tgaggactcc caggcaacat 227040 gaggggttcc acaggatctc cggaggccac aggtgttaag caggaactct ccatccttga 227100 ggcttgctgg gggtggcggg atggcagcag ggtgtgggtg atcgagttta tggattcagg 227160 ccaagattca agggtcaggc cccacccatt gccctgatgg gaccaaccct gttgtgcaat 227220 gggctgtccc actggtgcct ccttgagcct ggtgtgggca gcgtggcttc aatggggttg 227280 ggtcaaggct gagctctggc ccgcacctgg tggttggccc tgggaattgt ggactttggg 227340 ccaagggtgc agcccgcctg cctctggagg tcatcctacc cagaggtgga gtggccggaa 227400 gggtggcagg catcctgtgg tgaaaggccc actgttgagg gtcctgtccc accaatttgc 227460 tgttcaggct gcttctaagc catgggttca cctccagaga ggcgggatct tgagcccagg 227520 gaaaggagag ggcatcatgt gtcccctgat tggctgagaa tggggagagt gtttgggtgg 227580 tatgtggtgc atgaatgggg acccaccaga gaaggcgcgt ggccctgggc cccaggatgc 227640 aatttccggc gtgcttatag agggcgtctg agtggacact ctccatgccc aggcgcaggc 227700 tatgtgactg ccaggtctgc agcagtttgt ggcatctggg ctagcctcct tgattgctta 227760 tgagctggtt gatagccctg gcctgtgccg aggggtcctg gtgcggccct ggggttgttc 227820 aggggaagcc ggcatgggca gtggaggtgc tcttggggcc tgcagtaggg cacagcccag 227880 gtgttcttgc ttgagcgcag tgaaccacct gccctttcct tccagggttc ggtagcaggg 227940 agggccaagg gtcccccacg tccatgacag gtcagcgttc ctcctggatc ccatcacatg 228000 ggtacatgca gggagagcat gtgtgagccg gcactcccca ctctcttccc cgcattgcag 228060 ggtgaggccc tgtttggacc catcttccag ctatctcacc agatggtgag cccagaggaa 228120 gaccccgtgg ctctgggcca gtgtgcgtca gccaggtccc cagcccccag tgtgctgaag 228180 ctcaggccct tcccaacgcc ctggtctcct gcactgaggt gtggtgagca caaccaggtc 228240 ccactggatg catgcacagg gagggatgtg ccctaggttg ggtcgatgat gagaacctta 228300 tattgtcctg aagagaggtg atgacttaaa aatcatgctc aataggatta tgctgaggcc 228360 cagtctaggt taaaattctg gaagaggatg ctgggatccc aagttcacag gcagggccac 228420 tgtattttgg actagagaac tcgaggccct aaagggcatc ttgagggggt ccaacctgtc 228480 tctgtgctcc tccatgaggc agccctggct ccctgtgtgg ccttggtgtt ggtgctctgg 228540 ttcccaggcg tggcatgtgg gcacctcctt ccagagcccc cattctcccc tgtctctttc 228600 agtgagctct tccgcccatt tgggccctct gacattgacc ggcataggtg agtggatcct 228660 ctttgggtca tgggtcatga gcgaggcaaa gtggggtcac catgcatctg ccttcgggcc 228720 atgagagttt cctaaaagtg tggacctgaa ttcccaccgg ggatgagtta tccagaaggg 228780 ccacttcctt gggaatcgga cccaagaagg acgcctgtcc tgaagcccag caggggtggt 228840 ggtggtccag gcaggaaagg gttcattcag caccaagcag gcagctccca tctgagactt 228900 ggtgcatcgg tcaggccttg aggactgccc aggacacatg aggtggccac aggggctccg 228960 gggcactaca gggggtctgc agagaggggt aggcgattgg gtccgtgggg gtcatgccgc 229020 ggagtttcaa ggacacccat ggccctgaat gggactgacc ctgttgagta atgggccatc 229080 ccaatggcac ctccttgagt ctggcggtgg gtggtgctgt ttccctgggg ctaggtcaag 229140 gctgagctct ggctagtgcc tgtggtgctg caggctggcc ctagaactca tgggctttgg 229200 gccatgggga cagcttgtgt catgcttggg gtcacccctt cccggaggtt gaatggcggg 229260 agtggtggct tcctaaggtg ggaagtcctg ctattgagca acctgtcctg ggaatttgcc 229320 acccaggctg cttctgagac atgaggtcac ctccagagtg gcagcatctt gggtccaagg 229380 aaagaggagc ataacatgtg tccccagatt ggttgagtgt ggcctagctc tgtgtttggg 229440 aggtgtgcag ggtgtggatg gggatgtatc aaagaaagta catagccctg gagccccagg 229500 ctgtgatttc cagtgtgtgc ttggagaggg gcaggagcag gctctcgact gccaggtctg 229560 cagcagcgcg tggcatccgg gcaagccttc tggttggcca tgtgctggtt ggtggccctg 229620 gcctgtgccc agtggtctca gggtagacct ggcattgtgc agggcagcca gcagggcagt 229680 ggaggtgctc tcaggacctg cagtagggcg cagcctggac tttttgtgtg agaccagtga 229740 cccacctgca ctgtccttcc agggttgggt ggctgggagg gccaagggtg gtccatgttt 229800 gtctccgtga cacatcagtg ctctgcatgg atcctatcac atggatatcc cctacccacc 229860 ttccccacat ggaagcatga ggccttactt ggacatgtgt cctcctgtcc tagatggtga 229920 gctcggagga agacttgcat tgggcccaat ggagctgggc cagtttctgt cagccaggtc 229980 cccagctcct gatgcactga agctcaggcc cttcctggag ccctggtctc ctgccctgag 230040 ctgtggtgag cccatctggg tcccactgga tgcatgcatg ggagggggtt gccctcggtt 230100 gggtcgatga tgagaacctt atattttctg aagagaggtg atgacttaaa aatcatgctc 230160 aataggatta cgctgaggcc caacctaggg gagaattttg gaagaggacg ctgggatcct 230220 gaggtccgtg gcagggccac cgtattttgg gctggagacc tcaaggccct gaagggcatc 230280 ttggcagccc ccagccctgt ctctgcactc ctccgtgagg cagcccaggc tccctgtgtg 230340 ggcttggtgt cagagtccca ttccccaggg gcggggcagg ttggcggctc ctccctgagt 230400 cccctttctc ccttgtgtct ttgagtgact tcttctgccc aggtgggccc cctggcgttg 230460 accagcatag gtgagtggaa cctgctggtg tcatgggcca tgagccaggc catgtgggga 230520 ctccaggtca gccttcagga caggagagtt tcctcaggga gcaggggaat ccccactggg 230580 gagggatggg ttctcccaga gggccacttt cttttgaatc ggacccatgg aggacatctt 230640 ctctgaagac ctgcagaagt gatgatgttt caagcagcaa agggtttttt cagcccctgc 230700 agggcaggca gctcccagat gagattctgt gcatgggtca ggcctcaaga actgcccagg 230760 ccacatgcgg ggtgccacac aggctgtgag gcaccacagg ggtcatgcag gagctctcgg 230820 tcttcaggct tgttgtgggg gtggtgacag agtgatcagg cccacagggt caggctgcag 230880 tgtttcaagg atcgcgccca cctgtggccc tgaatgggac cgatgctgtt gagcaatgag 230940 ccatcccagt ggctccacat tgagcctggt gggggcgcca ctgtttcagt ggggatgggt 231000 gaagcttgag ctctggccag cacctgatgg tgttgcaggc tggcccaggg acttgtgggc 231060 tttgggccag gtcggcagcc tgagttctgc tgggggtcac atctttcctg agtttcagtg 231120 tcaggatgca tggcctcctt aggtgggaag gcctgctgtg gagggtcctg tcctgggaat 231180 ttgctgccca ggctgcttct gagccatggc gtcacctcca ggtggtgggg tcttgggccc 231240 aaggagcaga gaagacacca tgtggcccct gattggtcga gtatggcctg gctctgagtt 231300 tgggaggtgt gcagggcatg gatggggacc caccagagaa agcacgggcc aatgaagccc 231360 caggctgcga tttctgatgc gcacttggag agggcgcctg gttgggcgcc caccatgccc 231420 aagggtaggc tatgcaacta ccaggtctgc ggcagtgcct ggcatcagga ccagcctcct 231480 ttgttggctg tgagctggtt ggtggcccta gcccgtgtcc agtgatctct gtgcagccct 231540 ggggtcatgt ggagcagcca gtgtaggcag gggaggttat cttgaggtgt gcagtaggca 231600 catcccaggc atcttgcccg agcccagtga cctccctgcc ctgtccttcc agggttcggt 231660 ggcggggagg cccaagggta ccctgtgtcc atgacaggtc agtatttcat gtgaatccca 231720 tcacatgggc cctcctcctg tccccccaga tggtgagcct ggaggaagac ttgcactggg 231780 ccttctgtgc gccggccaga ggccatcaac caggtgccca ggtccttttg tactgaagct 231840 tgggcccttc ctggcaccct ggtctccttc atggagctgg tgagcccatc cgggttcttc 231900 tggatgtatg catggggagc ggggtgcact gggttgggtc aatgatgaga accttatatt 231960 gtcctgaaga gaggtgatga cttaaaaatc atgctcaata ggattacgct gagtcccagc 232020 ctaggtgaca attttggaag tggacactga gaatcacaag gaccctggca gggccactgt 232080 attttgggct ggagacctgg aggccctcaa gggcctctca cagggaccca accctgtctc 232140 tgcactcctc cgtgaagcac agcaggctcc ctgtgcggac ttggtgttgg cactgtttcc 232200 caggggcagg gcacattggt ggcttttccc tgagtcccca ttcttgcctt gtgtctttca 232260 gtgagctctt cagctcagaa gggccccttc accttgatta gcctaggtga gtgcatcctg 232320 ctggtgtcat gggccatgag tcaggccgcg tggggtcacc aagggtcagt ctttaggaca 232380 ggagggtttc ctcagggagc caacctgtat ttccaccggg gagggatggt ttctacagga 232440 gggcggcttc cttgggaact ggacccaaga tgttgccttc ctgaagccct gcagggatga 232500 cagtggtcca ggcagcaaag acttccttca gccccgtgca ggagagctcc cagctgagac 232560 tcagtgcatg tgtcaggcct cgaggattgc cgaggccaca tgatgggggc cacagggcct 232620 ccggggcacc acgggggtca tgcaagagtt ctctttccct ggagaggggt gcttgaatga 232680 gcctatggga ttgggccgtg gagattcaag gattgtaccc aactatgtcc caaaatggga 232740 ctgaccctgt tgagctatgg accatcccat ggtgcctctt tgagcttggt ggggggcagt 232800 gctgtttccc tgggtttggg tcaaggctga gctctggcca gtgcctggtg aggctgtggg 232860 ccggacctgg gactcgtgag ctttaggcca agtcgacagc ttgtgtcctg ctggaggtca 232920 ccccttcccc atgggtgagt ggctggaaga gtggaatgtg cggtgggaag gcccgctgtt 232980 gatggtccta tcctgagaat ttgctgccca gactctctgt gccatggggt catgtccagg 233040 gtggcagggt cttgggccta gggaaaggaa aggacaccat gtggcccagg attggccaag 233100 ggtggcccgg atctgtgttt gggacatgtg tggggcatgg atggggaccc accagagaaa 233160 gcacatggcc ctggtactcc aggctgtgat ttcaggtgtg gcttggagag agtgcctggg 233220 caggtgccca ccatgcccag cggcaggcta tgcaacttcc atgtccacgg tggcacatgg 233280 cttctgggcc aggctcctcg gttggccatg agcatgtcgg tgaccctgtc ccatgctcag 233340 tggtcctggg gcagccctgg gatcgtgtga aggagaagtc agagggggca ctggatgtgc 233400 cctcaaggtc tgcaatagca tgaagaccag gggtcttgcc caagcccagt gatccacctg 233460 ccctgttttt tcagggtttg gtgatgggga gggccgagag tgccctgtat ccgtgacagg 233520 tcagtgttcc acatggatcc catcacatgg gtatccctta ccccattccc cacctggagg 233580 tatgaggccc tgtttggaca catgtcctcc tcctgtccat ccagatggtg agcctgaagg 233640 aagacttgca tcaggaccaa tggaccctgg caagtgtccg tcagccaggt gctcagcccc 233700 tggtgcactg aagctcaggc ccttcctggc cccttgatct cctgcactga gctgtggtga 233760 gcacatccgg gtcccgctgg atgtatgtgt gggcaggggg ggtgccctgg gttgggtcaa 233820 tgatgagaac cctatattgt gttgaagaga ggtgatgact taaaattacc atgctcaatg 233880 attacgctga ggcccaacct aggtgagaaa tttggaggag gatgctggga tcccgagatt 233940 tccggcaggg ccactgtatt ttgggctgga gccctggagg ccctgaaagg tatctggagg 234000 aggcccaact ctgtctctgc actcctctgt gaggcagccc aggctccctg tgcgggcttg 234060 gtgttggcct ttctgttccc cagtgaagtg gcacgtgggt ggctcctccc tgagccccag 234120 ttctcccctt gtgtctttca gtgagctctt ctgccaaggg ggggcctcct ggcattgacc 234180 aacataggtg agtggatcct gctggcatca tgggcatggg ttcactgagg gtcagacttc 234240 aggccatgag ggtttcctca gggagctgac cccaattccc atcagggagg gatggtttct 234300 ccaggagggc ggcttccttg ggaatcttac ctgaggagga tgccttccct gaagatctgc 234360 aggaatgaca atggtccaga tagcaaaggg ttccttcagc cccatgcagg acatcgccca 234420 gttgagactt ggtgtgcagg tcaggccttg aggactgccc aggccacatg aggcgggcca 234480 gaagggctcc agggtgccac gggtttcact tgggagctct cggtccccgg gcatgttcct 234540 ggggggggtg gtgatggggt cgggccatgg aggttcaagg atctcatccc acctgtgacc 234600 ctgaatgggg ctgatcctgt tgaacaatgg gccatcccag tggcacgtat tgagcctggt 234660 caggggtggt gcagtttcaa tggggttggg tcaaggttga gatctggcca gctcctggtg 234720 gtgcttcagg ccagtcctgt gacccatggg ctttgggcta agggggcatc ccatgtccca 234780 tgggggtcac ctgttctcca tgtttgagtg gcagtaacag tggcattctg aggtgggaag 234840 gtccactgtc tagggtgttg taccgggaat ttgccacccc gccttcttag ccaaggggtc 234900 acctccaggg tctcgggatc ttgggcccaa ggaaacgaga agataccatg tggcccttga 234960 ttggccgagt gtggcccagc tctgtgtttg agaggtgtgg gatatgaatg gggtcccacc 235020 agtgaaagct catggcccag gtccccaggc tgtgattttt agtgcacact tggggagggc 235080 tcctcagtgg gtgcccacca cgcccagagg caggctatgt gactgccagg tctgcaacgg 235140 tgcatagctt ccaggctacc ctccttggtt ggctgggagc gggttggtgg ccatggccca 235200 tgcccagtgg tcacagggca accctgggat catgcagggg agctggtgag ggcagtggag 235260 gtgctctccg gaacggaagt atggctcagc ccaggtatct ggcccaaacc caatgaccag 235320 cctgccttgt ttctcagggt ttggtgatgg ggagggccaa gggtgccctg catctgtgat 235380 gggtctgttc cacatagaac ccattacagg ggatcccttc tccacatgga gatgtgaggc 235440 cctatttgga cacatatcct cctcctgtcc ccccagatgg tgagcctgga ggaagatttg 235500 cattgggccc aatggccctg ggccagtgtc tgtcagccag tttcccagcc cctggtgcac 235560 tgaagctcag gcctttcctg gcatcctggc ctcctgcact gagctgtggt gagtatatca 235620 tggtcctgct ggatgcatgt gcagggaggg aaggtgcctt gggttcagtc agtgtcgaga 235680 accttatatt gttctgaaga gaggtggtga cttaaaaatc atgctcaata ggattacgct 235740 gaggcccagc ctagttgaga attttggaag gggacagtag gatcccgaag tccctggcag 235800 ggcccttata ttttaggctg gagacttcaa ggccctgaag ggcacctgga ggtggctcaa 235860 cctgtctctg tgctcctcca tgaggcagtc caggctccct ctgtgggctt tctgttggca 235920 ctctggttcc ctgggccagg gaacgttggt ggctcctccc tgagcccctg ttctcccctt 235980 gtgtctttca gtgagtgctt ctgcccaggc aggccacttg gcattgaccg gtataggtga 236040 gtggatcctg ctggggtcat gggtcatgag caaggccaca tgggtcgccg agggtcagcc 236100 ttacagccat aagggttttc tcagggagcc cacctgaatt cccaccgggg aggcataggt 236160 tctccaggag ggcggcgttt tggggaatca gacccaaggg ggacaccttc cctgaagccc 236220 tgcaagggtg atggtggtcc aggcaggaaa gggttttttt cagccccaca caaggcagct 236280 cctagctgag aatcggtgct tgggtcagac ctcaaggatt gcccaggcca catgagggcg 236340 actgagagcc tccggggcac cacaggggtc acgtgggagc tctcggtgcc tggcgtgtga 236400 tgcacaaatg gacctcttgg gtttgttcat ggagattcaa ggatcgcacc ccaccatgcc 236460 cctgaatggg atggtccctc ttgagaaatg ggccatccca gtgggtctcc tggagcctgg 236520 ttggggggtg gcattgtttc cctggggttg ggtgaaggca gagttctggc cggcacctgg 236580 tggtgctgca ggtcagcact gggacccgtg ggcgttgggc caaaggagag cccgaatccc 236640 actgggggtc accctttttc caacatcaaa tgtctggaag ggtggcctcc tgaggtggga 236700 agtcctgctg ttgagggaca tgtcctggga atttgtcact caagcttctt ctgagctttg 236760 gtgtcacatc cagggtggca gggtcttggg tccaagcaaa gcagagggca ccatgtgtct 236820 cctgattggc caagtgttgc tggctctgtg tgggaggtgt gcagagtatg gatggggacc 236880 cacgagagaa agcacgtagc actgcaactc caggctatga tttctgttgc atgcttggag 236940 agggtgcctg gacaagcgtg ccatgcccag gggcaggctg ggcaactacc aggtcttcag 237000 cggagtgtga catctgggcc agcctccttg gttggccgtg acctggttgg tggcccggct 237060 ctgtgcctac tggccccagg gcagccctgg gatcatgcag gggagccatt ttgaacagtg 237120 gaggtgctct tggggcctgt agtatggcac agcctaggtg ttttgctcaa gcccagtgac 237180 ccacctgccc tgtcctctcc gggatcggtg gaagggaggg ccaaaggtgc tccgtgtact 237240 tgatgagtca gtatttcaca ttgaactcat cacatgtgtc catggagggt gagcaagggt 237300 gagatggcac tgctgacccc cttccccacg tagaggtcag tttggacact tgtcttcctc 237360 ctgtctcccc acatggcgac cccagaggaa aacttgtgtt gggcccgctg tcactgggcc 237420 aatgtcagtc agccaggtgc ccagcccctg gtgcgctgaa gcttgggccc ttctggcacc 237480 cttggctcct gcactgagct gtggtgagcc catctgggtc ctgctggatg catgtgcagg 237540 gagggggata cctgggttag gtcgattatg agaaccttat attgtcctga agagaggtga 237600 tgacttaaaa atcatgccca ataggattac gctgaggccc agcctaggtg agagttttgg 237660 aagaggatgc tgggattctg aggtccctga cagagtaaat gtattttggg ctggagacct 237720 tgaggccctg aagggcatct ggtgggccca cccctatctc tgtgctcctc cgtgaggcag 237780 cccaggctcc ctgtgctggc ttggtatctg ggctccggat ccctggttat ggggcatgtt 237840 ggagtctcct tcctgagtcc ccgttctccc ctgtgtcttt tggtgagctc ttctgcccaa 237900 gtggtccccg cggccttgag cggcataggt gagtgcatcc tgtttcggtc atgggccatg 237960 agtgatgcag catggggtcc tcgacattca gccttcgggc cactagggtt ttctcaggct 238020 gccaacctac tccccaccag ggagcaatgg tttctccagg agggccactt ccttgggaat 238080 ctgacccaag gagcacatct ttcctgaagc cctgcagggg tgacagtggt ccaggcagca 238140 aagggttcct tcagcccaat gtagggcagc tcccagctga aactcggtgg acagctcagg 238200 cctggagtac tgtccagggc acatggggag gaggggcaca gggaatgtgg cgcaccctag 238260 aggttacact ggagttctct ctccctggag aggggtgagt gattgggccc acacagtcag 238320 gctgtgaaga ttcaaggaat gctccacacc catggccttg aatgggacca accctgttga 238380 gcagtgggcc atcttatggt acctccttga gtctggtgag ggatggcact gtttcagtga 238440 ggttgggtca agactgagct ctggctggca cctggtgctg ctgcaggccc tgggacttgg 238500 gggccttcag tcaagggggc agctctgatc ctgctgggga caaaccttcc ttgaggtcca 238560 gtggtgaaga gtgtcctcct aaggtgggaa ggcctgctgt caagggaatt tgccacccag 238620 gctgcttctg agccttgggg tcacctcagg gtggcagggt cttgtgccca aggaaaggag 238680 aagacaccat ctggttcctg attggctgag tgtagccggg ctctgtgtgt cggagttggg 238740 cagggcatgg atggggaccc accagagaaa gtgtggccca ggggcccccc aggcttggag 238800 agggcaccag ggccggtgcc cacaatgctc aggtgctggc tctgggaggg ccaggtctgc 238860 agcggctttt ggcatctggc caaccacctt ggttggccag gagctggttg atggccctgt 238920 cctgtgtcct gtgccctgtg ccctgtgtcc ctggtatggc cctggggtca tgtgtgggag 238980 ctggcctgag cagtggaggt gctcttgggg cctgcagtag ggtacagcct aggcatcttg 239040 cctgagccag cactgtcttt tgctttccct gtctttccag ggtttggtgg cagagagggc 239100 aaaggatgcc ccacatctgt gttgggtcag tgttcagcat ggatcccatc acatgggtat 239160 cccttagccc cttccctgca ttgatatgtg aggccctggt tggacacatg tcctccttct 239220 gtccctctag atggtgagcc tggaggaaga tgtgtgggac ccgcaggccg agggccagtg 239280 tctctcagcc aggtgctcag cccccagtgg gctgaaactc tgacccttcc tggcaccctg 239340 ctctcctgca ctgtgctgtg gtgagcacat ccgggttcca ctggatgttt gtgcagggag 239400 ggggttccct gggttgggtc aatgatgaga acagggccac atgagggggg ccagaggggc 239460 tacagagtgc catggggtaa caagggagct cttggtccct ggagtgtggt gtgtgaatgg 239520 gcccatgggg ttgggtagca gagattcaag gatcctgctc tacccatggc cctgaatgtg 239580 accatcgctg ttgagcaatg ggccatccca gtgggtctcc tggggcctgg ttggggggcg 239640 gagttgtttc cctgggattg ggtcaaggtt gactctggct ggcacctggt ggtgttgcag 239700 gtcagccctg ggactcatgg gctttgggcc agggacagcc cgcatcccgc tgggggtcac 239760 ccaagtgttg tgaagggtgg cctcctgagt tgggaaggcc cgctattgag gcatctgtac 239820 tgggaatttg ttgctcacgc tgcatgggag ccatggtatc acctccaggg tggcagtctt 239880 gggaccaagc aaaggagggg gcagcatgag actccggatt ggctatgtgt gactggctat 239940 gtgtcttgga ggtatgtgga gtatggatgg ggacccacca gagaaaacaa gtgaccctga 240000 ggccccatgc tgtcttttct ggtgcctgca tggagagggt gcctgtacgc atgcccacca 240060 tgcccagggg caggctgtgc cactgtcagg tctgcagtag catgtggcat ctgggccagc 240120 ctccttggtt ggctgtgacc tggctggtgg cccggacctc tgcccagtgg tcccagggca 240180 gccctagggt catgcggagg agcagttttg gccagtggag gtgcccttgg gtcctgcagt 240240 cgtgcatacc ctgggcgttt tgcctgagcc cagtgaccta cctgccttgt ccttcccggg 240300 ttcggtggca gggagagaca cttgcatagg tgatgagtca gtatttcgca tggatctcat 240360 cacatgtgtc catggagggg gagcaagcgt gagctggcac ccaacacccc tttctccaca 240420 tggagggtgg tcacatgttc tccacctgtt cccctagatg gtgagacttc tgttgggctt 240480 gcttttcctg ggccagtgtc catcagccag gtgctcagcc atcggtgcgc tgaagctcca 240540 gcccttcctg gtgccctgat ctcctgcact gagctgtgat gagtacatcc gggttccact 240600 ggatgcatgt gcgggaaggg gggtgccctg ggttgggtca gtgatgagaa ccttatattg 240660 tcctgaagag aggtgatgac ttaaaaatca tgctcaatag gattacgctg aggcccagcc 240720 tgggggagaa ttttggaaaa ggatgctggg atcccagggt ccccaacagg gccactgtat 240780 tttggacctg ggacctggtg gctctgaagg gcatctggag gtggcccaac ctgtctctgc 240840 actctagttt ccctgtgtgg gcttggtgtc ggtgctccag ttccctgggg gcagggaatg 240900 ttgatggctc cttcctgagt ccctgttctc gcctttgtct ttcagtgagc tctttcacct 240960 aggagggccc cttggcattg actggcatag gtgagtggat cctgctggtg ttatggatca 241020 tgagccagac catatggggt ccccaaggat cagcctttgg gccacaaggg ttttctcagg 241080 gagctgacct gaatttccac ctgagacgga aaggttctcc tggaaggcag gctttttgga 241140 atcggaccca aggaggacac cttctctgaa gccctgaagg ggtgatggtg gtccaggcag 241200 gaaagggttc cttctgccta acataggaca gtgcctagtt gagactcggt gctgcagtaa 241260 ggccttgagg actgcccagg ctacatgagg ggggccagag gggctacggg gcaccacagg 241320 gttaatggtg acctcttggt ccccagagtg tggtgcgtga atggacccat ggtgttgggt 241380 tgtggagatt caaggatagt gccccaccta tggccctgaa tgcaactgtc cctgtttagc 241440 aatgggccat ctcagtgggt ctcctggagc ctggtggggg gcagagttgt ttccttgtga 241500 ctgggttaag gtagagctct ggccagcacc tggtggtgtg gcaggtcagc cctgggactc 241560 ttgggctttt gaccaagggg cagcctgtat cccgctgggg gtcatcctat ctctgaggtc 241620 aagtgtcgtg aagggtggcc tcctgaagtg ggaaggctcg ctgtcgaggg acctgtccta 241680 ggattttatt gctcaggctg cttctgagcc atggtgtcac ctctagggtg atggggtctt 241740 gggaacaagc aaaggggagg gcaccatgtt gctccggatt gggcaagtgt ggcccagctc 241800 tgtgtgtgtg aggtgtgcag aacatggatg gtgacccacc agagaaagca catggccctg 241860 tagctctagg ttgtgatttc cgtgcacact tggagacagc atcttgatgt gtgcccaaca 241920 cgcccagggg cagactatgc gatagccagg tctgcagcgg tgtgtggcat ctgggccagc 241980 cacctttgtt ggccatgagc tggctcatgg ccctgaccca tgcccactgg tgtcaggggg 242040 ccctggcgtc gtgtgaggag ccatctgtgg cagtggaggt agactcaggg cctgcagtat 242100 ggcgcaaccc atgcattttg cctgagctca gtgacctacc tgccctgttc ctccagggtt 242160 tggtggcagg gggagccaag ggtgccccac attggtgacg agttagtact tcacatggat 242220 ctcataacat gtgtccgtgg agggcaagca aatgtgagcc cgcacccact actgccttcc 242280 ccacatggag gtcagtttgg acacatatca tcctgctgtc ccccaaatgg tgagaccgaa 242340 gaagacttgc cctgggccct ctgttcttgg gccagtgtca gtcagccagg tgcccagctc 242400 taagtgcgct gaagcttggg cctttcctgg aatgctcggc tcccgcactg agccagggtg 242460 agcacatccg ggtactgctg gatgcatgtg tggggcaggg gtgcgccctg ggttgggctg 242520 atgatgagaa ccttatattg tcctgaaaag aggtgatgac ttaacaatca tgctcaatag 242580 gattacattg aagcccagga taggtaagaa ttagggaaga tgatgcaggg atcccaagat 242640 ctccagctag accacactta ttttgcactg gagaacttga gaacttgaag ggcatctcag 242700 gggagcccaa ccctgtctct gagctccttc gtgaggcagc ccaggctccc cttgcgggct 242760 tggtgtctgt gctccgcttc tccagggaca gggcaatttg gtgttccttc ctgaatgctc 242820 cttcttccct gtgtccttca gtgagctctt ctgcccaggt ggggtcccta gctttgagcg 242880 gcataggtca gtgcatcctg ttggggtcat gggccatgag tgaggcagca tggggttggt 242940 gagagtcagc cttcaggcca ctagggtttt ctcagggagc caaccgatta ctcaccggga 243000 gggatggttc ctccaggagg gtcacttctt gggaatctga ccctaggagc acacatttcc 243060 tgaagctcgg cagggagatg gtggtccagg caggaaaggg ttccttcaac ctaacgtagg 243120 gcagttccca gctgaaacta ggtgggcagg tgaggcttga ggactgccca gtccacatga 243180 aaggggccac aggggctttg gggtgccctg ggagtcatgc tggagttctt cccccaagag 243240 ggatgggtga tagggtccac gtggtcaggc tgcggagatt caaggaatgc cacccaccca 243300 tggccctgaa tgggaccaac cctgttgagc aatgggccat tttcggcatg tttcaatgca 243360 gttgggtcaa ggctgagcgc tggctggtgc ctggtggtgc tgcaggccgg ccctggggct 243420 catgggcttt atgccaaggg ggcaactccc atcccactgg ggtaatccct tccttgaggt 243480 ccagtggtgg gaagggtggc ctcctgaggt gggcagacct gctgtcaagg gacctgtcct 243540 gggaatttgc cacctaggct gcttctgagc catggggtca cctccaggat ggcggggtct 243600 tcagcccaag gaaaggagag gacaccatgt ggtttctgat tggctgagtg tggcctggct 243660 gtatgtgtgg gaggtgtgca gggcatggat ggggactcat cagagaaaga atgtggccct 243720 ggaggccccc aggctttgat ttctggtgtg tgcttggagt gggcaccagg gtggccctac 243780 catgcccagg ggcaaggtct ttgcctgcca ggtctggagt ggctcctggc atcaggacca 243840 ccctccttgg ctcaaccaac cttcagcagg ttggctgcct tggcccgtgc cccatggtcc 243900 cggtacgacc ctggggttgt tcgggggatc tggcccaggc agtggaggtg ctcttggggc 243960 ccacagtagg gcacagccca ggcctcttgc cccagcccag taacccactt gccctgtctt 244020 tccagggttt tgtggcaggg aaggccaagg gtgctctgcg tccatgttgg gtcagtgttc 244080 tgtaaggatt ccattacaag ggtatcccct acccaccttc cctacattga tacatgaggc 244140 cctggttgga cacatgtcct cctcctgtcc ctacagatgg tgaccctgaa gaaagacttc 244200 agttgggcct gaaggccccg ggccagtgtc catcatccag gtgctcagct cccagtgcac 244260 tgaagctcag acccttcctg gttccctggt ctcttgcact gagctctggt gagcacaact 244320 gggtgctgct ggatgcatgc atggggaggg gggtgccctg ggttggggtg gtgatgagaa 244380 ccttgtattc ttctgaagag aggtgatgac ttaaaaacca tgctcaatag gattacactt 244440 aggccgaacc taggtgagaa tgttggaaga ggacgttggg atcctattat ccctggcaga 244500 gccactgtat tttgggctgg agacctggag gccctgaaag ggcatctgga gggggcccaa 244560 ccctgtctct gtgctcctgc atgagggtcc ccaggctccc tgtccagcct tggtgttggt 244620 gctctggtac cctggggatg gaacaagttg gtggctcttt cctgagcccc cattctccct 244680 ttgtgtcttt cagtgagctt ttctgcccag gtgggcaccc tggcattgat tagcctcctt 244740 ggttgtccat gacctggctg gtggcccgat cctgtgccca gtggtcccag ggcagccctg 244800 gcatcatacg gggcagctgt tttgggcagt ggaggtgctc tccaggcctg aagtatggca 244860 cagcctgggc attttacctg agaccagtga cctgcctgcc ttgtccttcc tgggttcggt 244920 ggcagggagg gccaagggtg ccctgcgtca gtgatgagtc agtattttgt gtggatctca 244980 tcacctgtcc atggagggaa agcaagcatg agctggcacc caacaccccc ttctccgcat 245040 ggagggtggt cacatgtcct ccacctgtgc ccccagatgg tgagacttga ggaagacttc 245100 cactgggcct gcttttcctg agccagtgcc catcacccag gtgctcagtc cctggtgcac 245160 tgaagctcca gcccttcctg gcgccctggt ctcctgaact gagctgtggt gagcacatcc 245220 gggtttcact ggatgtttgt gcggggaggg ggttctctgg gttgggtcaa tgatgagaac 245280 cttatattgt cctgaagaga ggtgatgact taaaaatcat gctcaatagg attacgctga 245340 ggcccagcct aggggagaat tttggcagag gatgccggga tcccaagatt tccgggaggg 245400 ccacttgtat tttgggttgg agacctggag gccctgaagg gcgtctggag gtggcccagt 245460 gctttctttg cgctcctctg tgaggcagcc caggctccct ttgtgggctt ggtgtttgcg 245520 ctcctcttct ccagtgatgg ggcacgttgg gggctcctcc ctgagtcctg gttctcccct 245580 tgtgtctttc agtgagctct tctgccaagc ggttcccctg gcattgacca acataggtga 245640 gtggatcctg ctggcatcat gggctatgag ctaggccgca tgggtttgct gagggtcaga 245700 cttcaggccc caagggtttc ctcagggaac cgacctcaat tcccaccatg tgactgccag 245760 gtttgcaaca gtgcatagct tccgagctac cctccttggt tggccgggag ctggttggag 245820 gctgtggccc atgcctagta gtcacagggc aggcagactg ccctgttttt tcagggtgtg 245880 gtgacgggga gggccaaggg tgccctgcat ccatgatggg tcagggattt caggagggat 245940 ggtttctcca ggagggcagc ttccttggga atcttaccca aggaggatgt cttccctgaa 246000 gccctgcagg ggtgacgatg gtccagatag caaaggtttc cttcagcccc atgcaggaca 246060 tcacctagtt gagatatggt atgtgggtca ggccttgaag actgcccagg ccacctgagg 246120 ggcccagaag ggctctgggg tgccacaggt gttatgtagg agctctcagt ccccagactt 246180 gtttcgtggg gttggtgacg gggttgggtt gtggaggttc aaggatttca tcccacctgt 246240 gaccctgaat ggggccaacc ctgttgagca acaggccatc ccaatggcac gtattgagcc 246300 tggtggggtg tggtgcagtt tcaatagggt tgagtcaagg ctgagatcca tctggtgctt 246360 ggtgctgctg ctggccagcc ctgggacccg tgggctttgg gctaaggggg tagcccacat 246420 cctattgagg gtaacccatt ctccgagttt gagtaacggt taacagtggc attctgaggt 246480 gggaaggccc actgtctagg gtcctatact gggaatttgc caccccgggt tcttctgaga 246540 caagtggtca cctccagggt catggggtct tgggcccaag gaaaggagaa gataccatgt 246600 ggcccttgat tggctacatg tggcccaggt ctgtttggga ggtgtgtggg atgtggatgg 246660 ggtcccacca atgaaagcac atggcctggg tccccaggct gtgattttca gtgcacactt 246720 ggagagggtg cctcggcggg tacctaccac atccatgggc aggctatgtg actaccaggt 246780 ttgcaacagt gcatagcttc caagctaccc tccttggttg gtcgggagct ggttggaggc 246840 tgtggcccat gcctagtggt cacagggcag gcagacggcc ctgttttttc agggtatggt 246900 gatggggagg gccaagcatc catgatgagt cggtgttcca catggaaccc attacgtggg 246960 tatctcttac cccttcctca tatggagatg tgaggcccta tttggacaca tatcctcctc 247020 ctgtaccccc agatggtgag cctggaggaa gacttgcgtt gggcccaaag gccctagacc 247080 agtgtctgtc agccaggttc ccaacccccg atgcgctgaa gctcaagcct ttcctggcac 247140 cctggtctcc tgcactgagc tgtggtgagt atatcctggt cctgctggat gcatgtgcag 247200 ggaggtgggt gccttgggtt gggtcaatga tgagaacctt atattgttct gaagagaggt 247260 gattatttaa aaatcatgct caataggatt acgctgaggc ccagcctagt tgagaatttt 247320 ggaggaggac actgggatac cgaagtcccc cgcagggact ctgtattttg ggctggagac 247380 cttgaagccc tgaagggcat ctggaggtgg cccaacctgt ctctgtgctc ctccctgagg 247440 cagcccaggc tccttttgtg ggcttggtgt tggggctcca gttccccagg tcagggaata 247500 ttggtagctc tttactgagc ccctgttctc cctttgtgtc tttcagtgag ctcttctgcc 247560 caggcgggcc ccctggaatt gatgggtata ggtgagtgca tcctgctggg gtcatgggcc 247620 atgagccagg ccacgtgggg tcaccagggg tcccccttct ggccatgagg gttttctcag 247680 ggaaccgacc tgaattacca ctggggaggc ataggttctc caggagggcg gctattttgg 247740 gaatcggatc caagggggac accttccctg aagccctgtg ggtgtgatgg tggtccaggc 247800 aggaaagggt cccttccacc ccacacaggg cagctcatag ctgagagttg atgctcaggt 247860 caggcctcaa ggatttccca ggccacatga gggggacaga ggagctctgg gtgccacggg 247920 ggtcacatag gagctctcag tattcggtat gtcatgcaca aatgggcctc ttgggttgga 247980 ttgtggagat taaaggatcg cgcaccaccg tggccctgaa taggaccatc cttattgagc 248040 aatgggccat cccagtgagt ctcctggagc ctggtggagg ggagggggtg gcattgtttc 248100 cctggggatg ggtcaaggca gagctctggc cagcaccttg tggcttctgc aggtcagcct 248160 tgggactcat gggcattggg ccaaggggga gcccgcgtcc cactgggggt cacccttttt 248220 ccgacgtcaa gtatctggaa gagtggcctc ctgatgtggg aaggcctgct gtcgagggac 248280 gtgtcccagg agtttgtcgc tcaagtttct tctgagcttt ggggtcacat ccagggtggc 248340 ggggtcttgg gcccaagcaa agcagagggc accaagtgtc tcctgattgg ccatgtggct 248400 gtctctgtgt gtgggaggtt tacagagtat ggatggggac ccaccagagg aagcacgtgg 248460 ccctgcagca ccaggctgtg atttctgttg cacacttgga gaggttgcct ggacacgtgc 248520 ccttcatgcc cagtgacaga ctatgcaact accaggtctg cagcagggtg tgacatctgg 248580 gctagcctcc ttggttggcc gccacctggc tggtggcccg gatctgtgcc caacagtccc 248640 agtgcagcac tggggtcatg caggggagct gttttggaca gtggaggtgc tctcggggcc 248700 tgcaatatga tgcagcctgg gcgttttgct caagcccagt gacccacctg ccctttcctt 248760 tctgggttca gtggaaggga gggccaacag tgtagtgcgt acttaacaag tcagtatttc 248820 acattgaact catcacatgt gtccatggag ggcaagcaaa ggtgagctgg cacccccgac 248880 ccccttcccc aaacggaggt cagtttgggc acacgtctcc ctcctgtctc cccagatggt 248940 gaccccggag gaaaatttgt gttgggccca ctatccctgg gccaatgtca gtcagctagg 249000 cacccagccc ccagtgcgct gaagctcagg accttcctag tgccctcggc tcctgcactg 249060 agctctggtg agtccatctg ggtcctgctg gatgcatgag ctgggggcgg gagggtgccc 249120 tgggttgggt cagtgatgag aaccttatat tgtcctgaag aaaggtgatg acttaaaaat 249180 catgctcaat aggattacac tgaggcccag cctaggtgat aattttggaa gaggatgctg 249240 gaattctgag gtccctgaca gagcagctgt attttgggct ggagaccttg aggccctgaa 249300 gggcatcttg tgggcccacc cctatctctg tgctcctctg tgaggcagcc caggctccct 249360 gtgctggctt ggtatccggg ctctgggtcc ctggtgacgg ggcatgttgg aggctccttc 249420 ctgagcccct gttctccctt gtcattcagt gaactcttct gcacaagtga cccccccagc 249480 cttgagcggc ataggtgagt gcatcctgtt ttggtcatgg gccatgagtg atgcagcatg 249540 gggtccctga cattctgcct ttgggccacc agggttttct caggctgcca acctactccc 249600 caccagggag cgatggtttc tcaggagggc tgcttccttg ggaatctgac ccaaggagca 249660 agtctctcct gaggccctgc aggggtgaca gtggtccagg ctggaaaggg ttccttcagc 249720 ccaatgtagg gcagctccca gctgaaactc agtgggcagg tcaggcctcg agtattgccc 249780 aaggcacatg ggggagtgag gcacggggga tacagtgcgc cgtggaggtc acactggagt 249840 tctcccctcc ctggagaggg atgagtgact gggtccacac ggtcaggctg tggagattca 249900 aggcatgctc cacacccatg gccttgaatg ggaccaaccc tgttgagcaa taggccatct 249960 tagtggcacc tccttgagcc tggtggggga cggcactgtt tcaatgaggt tgggtcaaga 250020 gtgagctctg gctggcacct ggtggtgctg caggccctgg gacttgtgga ctttgggcca 250080 agggagcagc tctgatcctg ctggggacaa gccttccttg aggtccagtg gtgaaaagag 250140 tgtcctcctg agatggcaag gcctgctgtc gagggacctg ttctaggaat ttgctgccca 250200 ggctgcttct gagccttggg gtcacctcag ggggtggcag ggtcttgagc ccaagaaagg 250260 aaaagacacg atgtggttcc tgattggctg agtgtgaccc ggctctgtgt gtcagagttg 250320 ggcaggacat ggattgagac ccaccataga aagcatgtga tcctggaagc ccctaggctt 250380 ggagagggca ccagggccag cgcccaccac gcctaggtac gatctctcgg acttccaggt 250440 ctgcagcggc tcttggcgtc tgggccagca tgcttggttg gccaggggct ggttggtggc 250500 cctgtcttgt gccctgtgtc cccggtatgg ccctggggtt gtgtgtggta gcaggcctgg 250560 gcagtggagg tgctcttggg gcctgcagta gggtgctgcc caggcatctt gcccgagcca 250620 ggtgacacgc ttgccctgtc tttccagggt ttggcggcag ggagggccaa gggtgcccag 250680 tgtccgtgag ggatcagtat tcagcatgga tcccatcaca tgagtatccc ttagcccctt 250740 ctctacattg atgtgtgagg ccctggttag acacatttcc tcctcctgtc cctccagatg 250800 gtaagcctgg aggaagactt gtgttgggcc cacaggcccc aggccaatgt ctgtcagcca 250860 ggtgctcagc ctctggtgcg ctgaaactct gacccttcct ggcacactgg tctcctgcac 250920 tgagctgggg taagcacatc tgggttgcac tggatgtttg tgtggggagg gggttcccta 250980 ggttgggtca atgatgagaa cctgatattg ccctgaagag agatgatgac ttaaaaatca 251040 tgttcaatag gattacgctg aggcctagcc taggtgagaa ttttggaagc agatgctggg 251100 atcccaaggt cccttgcagg gccatcgtat gttgaactgg agacctggag gctctgaagg 251160 gcatctggag gtcgtgcaac ctgtctctgc actcctctgt gaggcagccc aggctccctg 251220 tgtggggttg gtgttggtgc tatggttccc tgggggtggg gaacattggt ggctccctcc 251280 agagcccctg ttctcacctt gtgcctttca gattttccac ctaggaggtc cacctggcat 251340 tgactgacat aggtgagtgg atcctgctgg ggtcatgggt catgagccag accatggggg 251400 gatcccagag attcagtctt tgggcaacag ttttctcagg gagcagacct gaatttccac 251460 ctgggaggga agggttctcc tggagggcga cttttttggg aatcggaccc aaggaggatg 251520 ccttccctga agccctgccg gggtgatggt ggtccaggca ggaaagttcc ttctgctcaa 251580 tgcagggcag cacccagctg agactcggtg ctccggtaag gcctccagaa ctgcccaggt 251640 cacataaggg gggccagagg ggctacgagg tgccacgggg taacagggga gctcttggtc 251700 cccagagtgt ggtgcatgaa tgggcccatt ccgttgggtc tcagagattt aaggattgca 251760 ccacaccatg gccctgaatg caaccgtccc tgttgatcaa tgggccatcc catgggtctc 251820 ctggagcctg gtgggaggca gtgttgtttt cctggggttg ggtcaaggcg gagctctggc 251880 tggtacctgg tggtgctgca ggtcagccct gggacttgtg ggctttgggc caaggggcat 251940 cccgcatccc gctgggggcc accctttctc catggtcgag tgtcgtgaag ggtggcctcc 252000 tgagttggga aggcttgcta ttgaggcact tgtactgtga atttgttgct caggctgctt 252060 gggagccatg gtgtcacctc cagggtggca gggtcttggg accaagcaaa ggagtgggca 252120 ccatgtcact gcagataggc catgtgtgac tggctctgtg tctgggagat atgtggagta 252180 tgaatgggga cccaccattc atagagaaag caagtggccc tgcagcccga ggctatgatt 252240 tccggtgcac acttggagag ggtgccttta cacccaagta ccaggctcag aggtaggcta 252300 tgccactatc aggtctgcag tggcacgtgg catctgggcc agcctccttg gttggccatg 252360 acctggctgg tggcctgggc ctgtgcccag tgttcccagg gtagttctag ggtgctgcgg 252420 gggagctgtt ttggctagtg gaggtgctct tgggtcctgc agtacagcac agcctgggcg 252480 ttttgcctga gcccagtgac ctgcctgcct tgcccttccc aggatcggtg gtagggaaga 252540 ccaggggtgc ccggcatagg tgatgagtca gtatttcaca tggatatcat cacatgtgtc 252600 catggagggg gagcaaacat gagctggcac ccgccacccc cttctccaca tgaagggtgg 252660 tcacacgttc tccatctgtt cctccagatg gtgagacttc tgtcggcctc gcttttcctg 252720 ggccagtgtc catcagccag gtgctcagcc ccagtgcact gaagctccag cccttcctgg 252780 cgccctggac tgagctgtgg tgagcacatc cgggttccac tggatgcgta tgtgggaagg 252840 ggggtgccct gggttgggtc aatgatgaga accgtatatt gtcctgaaga gcggtgatga 252900 cttaaaaata atgctcaata ggattacgct gaggcccacc ctaagtgaga aatttggtag 252960 gggatgttgg gatcccgaga tttctggcag ggccactgta gtttgggttg gaggcctgga 253020 ggccctgaag ggcatctgga ggtggctcaa ctctttctct gtgctcctcc gtgtagcagc 253080 ccaggctccc tgtgcgggct tggtgttgtt gcttctgttc cttgggggca gggcatgtgg 253140 gtggctcctc cctgagcccc agttctcccc ttgtgtcttt cagtgagctc ttctgccaag 253200 ggggtcctcc tggcattgac caacataggt gagtggatcc tgctgctgtc atggtccgtg 253260 agccaggctg cttggggttg ccaagggtca gacttcgggc catgaaggtt tcctcaggga 253320 gctgacccta attcccatga gggaggcatg gtttctccag gaggtcagct tccttgggaa 253380 tctgtgactt gacagggttg agtcgcagag gttcaaggat ctcatcccac ctgtaaccct 253440 gaatggggcc caccctgttg agcaactggc catcccagtg gcacatattg agcctggtgg 253500 ggggtggtgc agtttcaatg gggttgggtc aaggctgaga tatggctggt gcctggtggt 253560 gctgcagtcc agccctggga tccgtgggct ttgggctgag ggggaagcct gcatcctatt 253620 gggggtaacc tgttctccaa atttgagtga ttggtgggaa ggcctactgt ctgaggtcct 253680 gtactgggaa tttgccacct cagcttcttc tgagccatag ggtcacctcc agggtcatgg 253740 ggtcttggga ccaaggaaaa gagaagatac catgtggccc ttgattggcc gagtgtagcc 253800 cagctctgtg tttgggaggt gtgtgggatg tggatagggt cccacctgtg aaagcatgtg 253860 gcccgggtcc ccaggctgtg attttcagtg cacacttgga gagggcacct tggtgggtgc 253920 ccaccatgtc caggggcagg ctatgtgact gccaggtttg caatggtgtg tagcttcctt 253980 ctaccctcct tggttggctg ggagtgggtt ggttgctgtg gcccatgccc agtggtcaca 254040 gggcaggcag actgccttgt tttttcaggg tatgctgaca gggagggcca tgggtgccct 254100 gcattcatga tgagtcagtg ttccacatgg aacccattat gtgggtatct cttattcctt 254160 ctacatatgg agatgtgagg ccctatttgg acacatgtcc tcctcctgta cccccaggtg 254220 gtgagcctgg aggaagactt gcattgggcc caatggccct ggaccagtgt ctgtcagcca 254280 ggttcccagc ccccgatgcg ctgaagctca agcctttcct ggcaccctgg tctcctgcac 254340 tgagctgtgg tgagcatatc ctggtcctgc tggatgcatg cgtggggagg ggttgtccta 254400 ggttgggtca atgatgagaa ccttataatg ttctgaagag aggtgatgac ttaaaaatca 254460 tgctcaatag gattacgctg aggcccagcc taggtgataa ttttggaaga ggacactggg 254520 tcccgaagcc ccctgcaggg cccctgtgtt ttgggctgga gaccttgagg ccctgaaagg 254580 catctggtgg acccaactct atctctgccc tcctcaatga ggcagcccag cctccctgta 254640 ctggcttggt atccgggctc cgggtctctg gggacggggc acattggagg ctccttcctg 254700 agcccccatt ctctcctgtg tctttcagtg agctcttcgg cccaagtggt ccccccggcc 254760 ttaagcggca taggtgagtg catcctgttt tgatcatggg ccatgagtgt tgcagcatgg 254820 ggtccccgac attcagcctt caggccacta ggcttttctc aggctgcaaa cctactctcc 254880 accagggagc gatggtttct caggagggcc acttccttcg gaatctgacc catggagcac 254940 gcctttcctg aagccctgca gaggtgacag tggtccaggc aggaaggggt tccttcagcc 255000 ccaatgtagg gcagctccca gctgaaactt ggtggacaga tcaggcctgg agtactgccc 255060 agggcatatg gggaggaggg acacagggaa tgtggcgcac cctagaggtc acactggagt 255120 tctgtctccc tggagagggg tgagtgattg ggcccacatg gtcaggctgt ggagattcaa 255180 ggaatgctcc acaccgatgg ccttgaatgg gaccaaccct attgagcaat gggccatctt 255240 agtggcacct ccttgaacct ggtgggggat ggcactcttt caatgaggtt gggtcaaggc 255300 tgagctctgg ctggcaccca gtggtgctgc aggctggccc tgggacttgt gggctttggg 255360 ccaaggggga agcttccatc ctgctgggaa caacccttcc ttgaggtcca gtggcaggaa 255420 ggggggcttc ctgaggtgga aagccctact gttgagggac ctgtcctggg aatttgctgt 255480 ccaagctgct tctgagccat ggggtcacct ctagggtggt ggggtcttga gcccaaggaa 255540 aggagaggac accatgtggt tcctgattgg ctgagtgtgg cccggctctg tgtgtcggag 255600 ttgtgcaggg tatggattgg gacccaccag tgaaagcaca tggccctgga ggtccgcagg 255660 cttggagagg gcaccagatc tggcacccac catgcccagg tacaggctct gggactgcca 255720 ggttgcagca gctcttggca tctgggccac cctccttggt tggccaggag ctagttggtg 255780 gccctgtccc atgccccatg tccctggtat ggccatgggg tcatgcagag gaaccggccc 255840 tggcatggag gtgctcttgc aacatgcagt agggtgcatc ccaggcatct tgcctgagcc 255900 aggtgacccg cttgccctgt ctctccaggg tttggtggca gggagggcca agggtgcccc 255960 gtgtccatgt tgggtcagtg ttcagcatgg atcccattgc atgagtatca cttagctcct 256020 tcccagcatt gatatgtgag gccctggttg gacacttgtc ctcctgtccc tccagatggt 256080 gagcctggag gaagactcgt gttgggccca caggccccag gccagtgtac gtcagccagg 256140 tgctcagccc atggtgtgct gaagctctga cccttcctga ctccgtggtc tcctgcactg 256200 agctgtgatg accatatcca ggtcctgcta gatgcatgcg tggggaggca gggtgccctg 256260 ggttgggtca atgatgagaa ccttgtatta tcttgaagag aggtgatgac ttaaaaatca 256320 tgctcaatag gattacactg aggcccagac taggtgagaa ttttggaaga ggatgctggg 256380 atcctgaggt ccccaacagg gccaccatat tttgggctgg agacctggag gtcctgaagg 256440 gcatctgtag ggggcccaac cctgtctctg cactcctccc tgaggcagcc catgctccct 256500 attcgggatc ggtattggtg ctccacttcc ctgggggcag gacacgtggg tggctactcc 256560 ctgagccccc gttctcccct tgtgtctttc agtgagctct tccaaacagg tgggctccct 256620 agcattgacc gacagaggtg agtggatcct tctgggatta tgggccatga gccaggccat 256680 gtggggtccc caaggttcag cctttggatc ccgagagttg tctcagacag ccaacctgat 256740 ttgccacctg ggagagatgg cttctccagg agggtgggtt tttgggaatt ggacccaagg 256800 aggacgcctt ccctgaagcc ctactgggat gatggtggtc caggcaggaa agggttcctt 256860 cacccagctg agactcggtg ttccagtaag gcctcaagga cctccctgcc acatgaaggg 256920 gcccagaggg gctacgaggc accacaggag tgacagggga gctcttggtc cccagagtgt 256980 ggtacatgaa tgggcccatg gggttgagtc gcagagattc aaggatgctg caccacccat 257040 ggccctgaat gtgactctcc tcctggagcc tggtgggggg tggcgttttt tccctggggt 257100 tcggtcaagg tggaactctg gtcagtacct ggtggtaatg taggtcagcc ctgggactcg 257160 tgggctttgg gccaacggac agcccacatc cctctggggg tcaccctttc tctgaggtcg 257220 agtgtcgtga agggtggcct cctgaggtgg gaaagcccaa tgtcgaagga cctgtactga 257280 gaatttgttg cttaggctgc ttaggatcca tgttgtcacc tccagggtgg tgggatcttg 257340 ggaccaagca aaggagaggg caccatgtgg ctgccagtgg ctatgtgtga ctggctctgt 257400 gtctgagagg tgtgtggatg gggacccacc agagaaagca agtggccctg cagccccaag 257460 atgtgatttc tggtgcaggc ttggagaggg tgcctatacc tgctcccacc acgcccaggg 257520 gcaggctttg ccactgcagg tctgcagtgc cacgtggcat ctgggccagc caccttggtt 257580 ggccgtgacc tggctggtag cccgtgcctg tgcccagtgt tcccagggct gccctggggt 257640 cttgctgggg agctgttttg ggcagtggaa atgctcttgg ggcctgcagt atggcacagc 257700 ctgggggcat tttgcctgag cccagtgacc tgcctgcctt gtccttcctg ggttcggtgg 257760 cagggagggc caagggtgcc ctacattggt gacaagtcaa tattttgcat ggatctcatc 257820 acgtgtccat ggaggtgggg gcaagcgtga gctggcacgc accccattct ccccatggag 257880 ggtggtcaca tgtactccac ctgtgtccct agatggtgag actggaggaa gacttccatt 257940 gggcccactt ttcatgggac agtgtccatc agccaggtgc tcagccccca gtgcattgaa 258000 gacccagccc atcctggcac cctagtctcc tgcactgagc tgtgctgagc acatctggct 258060 tccactggaa gttttttttg cgaggagggg cttccctggg ttgggtcaat gatgagaacc 258120 ttatattgtc ctgaagagag gtgatgactt aaaaatcatg ctcaatagga ttacgctgag 258180 gcccaaccta ggggagaatt ttggaagagg attatgggat cccaaggtcc ccaacaaggc 258240 cactgcattt tgggctagag acctggaggc tcttaagagc atctggaggt ggcccaacct 258300 gtctctgctc cttcgtgatg cagcccaggc tccctgtgtg ggattggtgt tggtgctcca 258360 tttccctggc atggggaatg ttggtggctc cttcctgagc tcctgttctc gccttgtgtc 258420 tttcagtgag ctctgccacc caggacatcc ccctggcatt gactggcata ggtgagtgga 258480 tcctgctggg gtcattggtc atgagccaga ccatgtggag tccccaaggt tcagcctttg 258540 ggccacaaag gttttctcag ggagcagacc tgaatttcac ccgggaggga agggttgtcc 258600 tggagggtgg cttttttggg aacctaaccc aaggaggacc cattccctga agccctgcag 258660 gggtgatggt ggtccaggca ggaaagggtt ccttctgctc aatgcagggc aacacccagc 258720 taagatgcgg tgatctggta aggcctccag aactgcccag gccatatgag gggggccaga 258780 ggggctacag ggtgccacag gggtaacagg ggagctcttg gtccttggag tgtggtgcct 258840 gaatggaccc atgggattgg gttgtgtaga ttcaaggatc acaccctacc cacagccctg 258900 aatgtgactc ttcctcttga gcaatgggcc atctcagtgg gtctcctgga gcctggtcgg 258960 ggggtggtgt tgtttccctg gggttgggtc taggtggagc tctggctggt acctggtggt 259020 gctgcagatc atccctggga cttttgggct ttgggccaag ggacagcccg catcccgctt 259080 ggggtcagcc tatctccatg gtcaagtgtc atgaagggtg gccccctgag gtgagaaggc 259140 ctactgtcaa gggatctgtc ccaggatttt gttgctcagg ctgcttctga gccatggcgt 259200 cacatccaca gtggcagggt cttgggcctg agcatagcag agggcaccat gtcgttctgg 259260 attggccaag tatggcctag ctctgtgtgc gggaggtgtg cagagcatgg acggtgaccc 259320 accagagaaa gcacgtggcc ctgcatccca ggctgtgatt tccaatgcac acttggagag 259380 ggtgtcttga tttgtgccca ccatgcccag gggcagacta cgtgatagcc aggtctgcag 259440 cctgagccac gtgtggcatc tgggccagcc accttggttg gccgtgagct ggctggtggc 259500 cttggcctgt ggccagtggt gccagggcgg ccctggggtc gtgtggggga gccatgttgg 259560 gcagtggagg tgctgtcagg gcctgcagta cagtgcagcc tgggcatttg gcctgagccc 259620 agtcacccgc ctgctctgtt cctccagggt ttggtggcgg ggagggccaa gggtgccccg 259680 catccgtgac gactcagtaa ttcacatgga tcacatcaca tttttccttg gagggcaagc 259740 aaatgtgagc ccccaccccc cactgccttc cccacatgga ggtcattttg gacacatatc 259800 ctcctctagt ccccctagat ggtgagactg gaggaagact tgcattatgc ccgctgttcc 259860 tgggccagtg tcagtcagcc aggttcccag ctccaagtgt gctgaagctc aggcccttcc 259920 tggcaccctc agctcctgca ctgagctggg gttacatccg ggttccactg tttgcatgca 259980 aagggagggg tgtaccctgg gttgggctga tgatgagaac cttatattgt cctgaaaaaa 260040 ggtgatgact taaacatcat gcttaatagt attatgctga agcccaagct aggtgagaat 260100 tttggaagat gaggctggga tcctgagatc cccggcaggg ccacacttat tttgggctgg 260160 aaaatttcaa gacctgaagc gcatcttgtg ggggggcaat cctgtctctg tgcttctccg 260220 tgaggcagcc caggctcccg ttgcgggctt ggtgcccatg cttcgcttcc ccaggggtgg 260280 ggcaatttgg catcctcttc ctgagccctc cttcttccct gtgtctttca gtaagttctt 260340 cttcccaggt ggggcccctg gctttgagcg gcatgggtca gagcatcctg tcagggtcat 260400 gggccatgag tgaggcagcg tcggttcgtc gagagtcagc ctttgggcca ctggggtttt 260460 ctcagggagc caacaggtta cccatcagga gggatggttc ctccaggagg gtcgcttcct 260520 tgggaatctg actctaggag catgcatttc ctgaagctct gcagggtgat ggtggtccag 260580 gcgggaaagg gttccttcag cccaacataa tgcagttccc agctgaaact cggtggcaga 260640 tcaggctcaa ggactgctcg ggccacatga tgggggccac aggggatttg gggtgccctg 260700 ggggtcatgc tggagttctt gccccaagag gggtgggtga tagggcccat gcgatcaggc 260760 tgcggagatt caaggaatgc tacccaccca tggccctgaa tgggactgac cctgttgaac 260820 aatgggccat tttaatggtg cctccttgag cctggtaggt agtggcattg tttcaatgcg 260880 gttgggtcaa ggctgaactc tggctggtgc ccggtggtgc ccacatgggc tttgggccaa 260940 gggggcagct catatccctc tggggtcacc ccttccttga gattcagtgg caggaagggt 261000 gttctcctga ggtggaagac ctgctgtcaa gggacttgtc ctgggaattt gccacctagg 261060 ctgcttctga gccatggagt cacctccagg gtggcagggt cttgagccca gggaaaggag 261120 acaccatatg gtttctgact gggagtgtgg cctggatctg tgtgtgggag gtgtgcaggg 261180 catggatggg gacccatcag agaaagcatg tggccctgta ggcccccagg ctttgatttc 261240 tggtgtgtgc ttgcagtggg caccagggca gccctaccat gcccaggggc aggctctgtg 261300 actgccaggt ctggagtggc tcctggcatg aagaccacgc tccttggttg gccatgagca 261360 ggttggttgc cctagcctgt gccctgtggt cctggtgcag ccctggggtt gtttggggag 261420 acagcaccgg cagtggaggt gctctcaagg cctgcagtag ggcgcagccc aggtgtcttg 261480 cccgagccca gtaacccact tgccctgtct ttccagggtt tggtggcagg gagggccaac 261540 tgtgccccgc atctgaaatg gatcagtgtt ctgcatggat cccatcacaa gggtatcccc 261600 tacccaactt ctgtgcattg ttatgtgagg ccctggttgg acacatgtcc tcctcctgtc 261660 cctgcagatg ctgaccctgg aggaagactt gtgtcgggcc cccaggcccc aggccagtgt 261720 ccatcagcca ggtgctcagc tcccagtgcg ctgaagctca gacccttcct ggcaccctgg 261780 tgtccagcac tgagctgtgg tgagcccatc cgggtcctgc tggatgcatg aatggggagg 261840 ggcctgccca gagttgggtc aatgatgaga accttacatt gtcctgaaga gagatgatga 261900 cttaaaaatc atgctcaata ggattacgct gaggcccagc ctaggtgaga attttggaag 261960 aggacggctg ggatcctgag atcccagtca gggtcactgt attttgggct ggagacctgg 262020 aggccctaaa gggcatctgg aagggggccc agccctgtct ctgtgctcct ccgtgaggca 262080 acccacactc cctgtgtggg cttggtgttg gtgctctggt tccccaggga cagggcgggt 262140 tggtggctcc ttcctgagcc cctattctcc ctttgtgtct ttcagtgagc ttttccaccc 262200 aggtgggccc cctggcattg accgacatag gtgagtgcat cctactggga taatgggcca 262260 ctagatagtc tgtgtggggt tgctgaggtt tagcctttgg gccacaaggg ttttctcagg 262320 cagccaacct gaattcccac ctgggagaga tgggttctcc aggaggcagc ttttttggga 262380 atcagaccca aggaggacac cttccctgaa gccctgcagg ggtgatggtg gtccaggcag 262440 gaaagggttc cttctgccca actcgaggcc caatgcaggg cagtgccccc ctgagaattg 262500 gtgctctggt aagggctcga ggactgccca ggccacatga aggaggtcag aggggctatg 262560 gggaaccatg ggggcaacag gggagctctt ggcccccgga gtgtggtaca tgaatgggcc 262620 catggggttg ggtcacggag attcaaggat tgcatctcac ccacggccct gaatgcgacc 262680 atccctgttg agcaatgggc catcccagtg ggtctcctgg ggcctggtgt ggggtggcat 262740 tgttttcctg gggttgggtc aaggcggagc tctgactggt acctgatggt gctgcaggtc 262800 agccctggga ctcgtgggct ttgggccaag aggcagcccg catcctgctg ggggtcgcct 262860 tttctccgag gttgagtgtc gtgaaggatg gcctcctgag gtgggaaggc ccactgtcaa 262920 ggcacctaga ctaggaattg ttcctcaggc tgcttgggag ccatggtgtc acctccaggg 262980 tggcgggatc ttgggactaa gcaaaggagg ggacactacg tggctcccaa ttggccatgt 263040 gtggctggct ctgtgcctgg gaagtgtgtg gagtatggat ggggacccac cagagaaagc 263100 aagtggccct gcagtcccag aatgtaattt ctggtgtagg cttggagagg gtgcctatat 263160 gcatgcccac catgcccagg agcaggctat gccacttcag ggtctgcagg ggcacctggc 263220 atatgggcca gcctccttcg ttggctgtga cctgggtggt ggcctgtgct tgtgcccagt 263280 ggtcccaggg tagccctggg gtcgtgcagg ggagccgttt tgggcagtgg atgtgctctc 263340 gggtcctaca gtacagcaca gcctgggtgt tttgctcaag cccagtgacc tgcctgcctt 263400 gtccttcccg ggttcagtgg cagggagagc caagggtgcc ccacattggt gacgagtcag 263460 tattttgcat ggatctcatc acacgtgacc atgaaggacg agcaagcatg agctggcacc 263520 agccaccccc ttctccgcgt ggagggtggt cacatgtcct ccacctgtgc ccccagatga 263580 tgagactgga ggaagacttc cattgggccc acttttcctg ggccagtgtc catcagccag 263640 gtgctcagcc cctggtgtac tgaagctcca gcctttcctg gtgccccagt cttctgcact 263700 aagctgtggt gagcacatcc gggttccact ggatttttgt gcggggaggg ggttttctac 263760 gttgggtcaa tgatgagaat cttatattgt cctgaagaga ggtgatgact taaaaatcat 263820 gctcaatagg attacgctga ggcccagcct aggtgagaat tttggaaggg gattatggga 263880 tgctgaggtc ctcagcaagg ccactgtatt ttgggctaga gacctggagg ctctgaaggg 263940 catctggagg tggcccaacc tgtctctgcg ctcctccatg aggcagccca ggctccctgt 264000 gcagggttgg tgttggtgct ccggttctct ggtgtgggga atgttggtgg ctccttcctg 264060 agccctcatt ctcaccttgt gtctttcagt gagctcttcc acccaggagg gccccttggc 264120 attgactggc ataggtgagt ggatcctgct ggggtcattg gtcatgagct agaccgtgtg 264180 gggtccccga ggttcagcct tcagtccaca agggttttct cggggagcag acctgaattt 264240 ccacctggga gggaagggtt ctcctggagg gtagtttttt tgggaatcta gcccaaggag 264300 gatgccttcc ctgaagccct gcaagggtga tggtggtcca ggcaggagag ggttccttct 264360 gcccaatgca ggacagctcc cagttgagac tgagtgctcc agtaaggtct ccaggactgc 264420 ccaggccaca tgaaggaggc cagaggggct atggagcacc actggggtaa taggggagct 264480 cttggtccct ggagtgtggt gtgtgaatgg ggtttggtca cggagattca aggatcacac 264540 cccacccatg gccctgaaag tgaccatccc tattgagcaa tgggccatcc caccgggtct 264600 cctggagtct ggtgcagggc gacgtttttt ccctggggtt gggtcaaggt ggagctctgg 264660 tacctggtca tgctgcaggt cagccttggg actcgtaagc tttgggccaa gggacagctg 264720 gcatcctgct ggggggtcac cctatctctg gggtcgaatg tcacgaaggg tggcctcctg 264780 aggtgggaag gcccattgtc gagggacctg tcccaggatt ttgttgctca ggcttcttct 264840 gagccatggt atcacctcca gggtgacagg gtcttgggcc caagcaaagg agagggcacc 264900 atgtcgctct gagttggcca agtgtagcct agctctgtgg tgggaggtgt gcagagcatg 264960 gctggtgacc caccagagaa agcacgtggc cctgcagccc caagctgtga tttccagtac 265020 atgcttagag agggcatctt gatgtgagcc caccacaccc aggggcagac tacgtgactg 265080 ccaggactgc agtggcacat ggcatctggg ccagccttct tggttggcca tgacctagct 265140 aatggccctg gcccgtgcct tggggtcatg caggggagcc ctcttggaca gtggaggtcc 265200 tctcagggcc tgcaatatgg cgcaggctgg gcatttggcc cgagcccagt gacctacctg 265260 ccctgtcctt ccagggttgg gtggcaggga gggacaaggg tgccccatgt cagtgacaag 265320 tcagtatttc acatggatct catcacatgt gcccatggag gacgagcaag cgggaactgg 265380 cacccgctac ttccttccct acatagaggc cattttggac acatgttctc cacctctctc 265440 ccagatggtg agacgggagg aagacttgtg ttgggcctgc tgttcctggg ccagtggcca 265500 tcagcctgtt gcccagcccc tgaggcgctg aagctcaggc ccttcctcac accctggtct 265560 cctgcactag ctgtggtgag cacatccggg tcccgctgga tgcatgcaag aggtggttgg 265620 tctcgtgggt tgggtcgatg atgagaacct tatattttcc tgaagagagg tgatgactta 265680 aaaatcatgc tcaataggat tacgctgagg cccagcctag gtgagaactt tggaagagga 265740 tgctgggatc ctgagatccc aggcagggcc actatatttt ggggtggaga actcaaggcc 265800 ctgaagggcc tctcaggggg tgccaccctg tctctgtgcc cctctgtaag gcagcccagg 265860 ctccctgtgt gggcttggtg tctggtctct ggttccccgg gggcggggca tgttggtggc 265920 tccttcctga gcccgctttc tcccccatgt ctttcagtga gctcttctgc ccaggtgggg 265980 cccatggcct tacacgacat aggtgagtgt atcctgttgg ggtcatgggc catgaatgag 266040 gcagcatggg gccatttagg gtcagccttc gggccactag agttttctca gggtgcgacc 266100 ggggagggaa catttctcca gtagggtcac ttccttggaa atctgatcct aggagcacgc 266160 atttcttgaa gtcctgcaaa ggtgatggtg gtccagacag gagagggttc cttcagccca 266220 acatagcgca gctcccagct gaaactcgga aggctggtca ggcctcgagg actgcccagg 266280 ccacatgagg tgggcaacag gggctctggg gcaacctggg ggtcacgctg gagttctccc 266340 tctctggaca gtggtgggtg attgggccca cgcagacagg ccccggagat tcaggactgc 266400 accccatcca tggccctgaa tgggaccgac cctgttgagt aatgggccat ctcagtggta 266460 cctccttgag cctggtaggg ggagacactg tttcaatgca gttgaatcaa ggctgagctc 266520 tggctggtgc ctggtggtgc tgcaggcagc cctgagggtt gtggtctttg ggacaagggg 266580 tagctcacat cccactgggg tcaccccttc cttgagattc agtggccaaa agggtgtcct 266640 cctgagatgg gaagtcctgc tgtcgaggga cctgttctgg gaatttgcca cacaggctgc 266700 ttctgagcca cggggtcacc tccagggtgg tagggtcttg atcccaagga aaggagagga 266760 caccatgtgg tttcttattg accaagtgtg gcctggcttt gtgtgtggga ggtgtaacgc 266820 aagatgagga cccaccagag aaagcacgtg gctctggagg cccccagggt ttgatttccg 266880 gtgtgtgctt ggagagggca ccaggttggg cacccaccac gcccagggca ggctctgcga 266940 ctgccaggtc tgcattggct cctggtgtca gggccagact cattggttgg ccatgagcag 267000 gttggttgcc ctgacccatc cccatggtcc cagtgtggcc ctggggtttt tcaggggagc 267060 cggctcaagc agtggaggtg cgcttagggc ctgcagtagg gaacagccca ggcatcttgc 267120 ctgagcccag taacctgctt gccttgtctt tccagggttt ggtggccggg agggccaatg 267180 atgctctgcg tctgtgttgg atcagtgttc ttcatggatt ccatcacgtg ggtatcccct 267240 acccaccttc cccttgctca tacgtgaggc cctggttgga cacatgtcct tctcctgtca 267300 ccccagatgg tgagccttga ggaagacttg tattgggccc ccacaggccc caggccagtg 267360 tccgtcagcc tggtgctcac ccccagtgtg ctgaagctca gaccctccgt ggcaccctgg 267420 tctcctgcac tgagctgtgg tgagcacatt caggttccgc tggatgcatg catggagagg 267480 ggcttgccct tggttgggtc agtgatgaga accttctatt gtcctgaaga gaggtgatga 267540 cttaaaaatc atgctcaata ggattacgct gaggcccaac ctaggtgagt atgttggaag 267600 aagacactgg gatcccgaga tctccaacag ggcactgtat tttgggttgg agacctggag 267660 gccctgaagg gcatctggaa ggaggcccaa ccctgtctct gtgctcttcc ttggggcagc 267720 ccaggctacc tctgcgggct tggtgttggt gctccagttc cctggggcca gggaacattg 267780 ctggctcctt cctgagcccc cattcctccc ttgtgtcttt cagtgaactt ttcctcccag 267840 atgggccccc tggcattgac tggcataggt gagtgcatcc tgctggggtc atgggccatc 267900 agccaggcca tgtggggtcg ctgaggttca gcctttgggc cacaagggtt ttctcaggca 267960 gccgacctga attcccacct gggagagacg ggttctccag gagggcagct tttttgggaa 268020 ttagacccaa ggaggatacc tgaagccctg caggggtgac ggtggtccag gcaggaaagg 268080 gttccatcag cccgggcaag gcagctccta gctgacactc ggtgttcggg tcagtccttg 268140 aggactgcct gaacacgagg gggtccagag gggctctggg tgccacgggg gtcacatggg 268200 agctctcagt ccctagagtg tggtgtgtga atggaccctt agggttaggt cttggagata 268260 aaaggattgt gctccaccca tggcctggaa tgtgaccgtc cctgttgagt aatgggccat 268320 tccagtgggt ctcctggagc ctgatgggag gtggcgttgt cttcctgggg ttgagtcaag 268380 gcagagctct ggcccatacc tggttgtgct gcaggtcagc cctgggactc gtgggctttg 268440 ggccgagggg cagcccgcat cccgctggag attaccctat ctctgagatc aagcgtcata 268500 gagggtgacc tcctgagaag ggaaggccca ctgtcgaggg acctttccta ggattttgtt 268560 gctcaggctg cttggaatcc attgtgtcac ctccagggtg atggaggttt gggcccaagc 268620 aatggagagg gcaccatgtg tctcctgatt gttcaagtgt gtcggagata tgcggggtat 268680 ggatggtggc ccaccaaaga aagcatgtga ctcaagctgt gatttccagt gcatgcttag 268740 agagggcgcc tgtatgcgtg ccccacatgc ccggggtagg ctatgcaact gccaggtctg 268800 cagtggcgca tggcatcttg gccagccttc ttggttggcc atgacctggc taatgaccct 268860 ggcctgtgcc cagtgatccc agggaagccc tggtgtcatg cagcggaggc ctcttgggca 268920 gtggaggtgc tcttaaagcc tgcagcatgg cacggcctgg gcatttatcc caagcccaat 268980 gaactacctg ccctgtcctt ccagggttcg gtggcaggca gggccaaggg tgccccgtgt 269040 tggtgacaag tcagtatttc acatggctct catcacatgt gtccgtggaa gataagcaag 269100 tgtgaactgg cacgtcctac ctccttccct acatggaggt aactttggac acatgttctc 269160 cacctctctc ccagatggtg agaccggagg aagacttgca ttgggcctgt tgttcctggg 269220 ccagtggcca tcagcctgtt gcccagcccc tgatgcgctg aagctcgggc ccttcctcgc 269280 gccctggtct cctgcactga gctgtggtga gcacatccgg gtcctgctgg atgcatgcac 269340 gaggtgattg atcccctcag ttgggtcgat gatgagaacc ttatattgtt ctgaagagag 269400 gtgatgactt aaaaatcatg ctcaatagga ttacgctgag gcccagccta ggtgagaatt 269460 ttggaagagg atgctgggat cccgagatcc ctggcagggc cactatattt tgggctggag 269520 aacttgaggc cctgaagggc atctcagggg ggtccaaccc tatctctgtg cccctccatg 269580 aggcagccca ggctccctgt gtgggcatgg tgtccgggct ctggttccct gggggtgggg 269640 catgttggtg gctccttcct gagcctgctt tctcccccat gtctttcagt gagctcttct 269700 gcccaggtga ggcccatggc cttaagcggc ataggtgagt gtatcctgtt ggggtcatgg 269760 gccatgaatg aggcagcatg gggccattta tggtcagcct tcgggccact agggttttct 269820 cagggtgcga ccggggaggg aatgtttctc cagtagggtc acttccttgg gaatctgacc 269880 ctaggagcat gcatttcgtg aagccctgca aaggtgatgg tggtcccggc aggaaagggt 269940 tccttcagcc caacatagag cagctcccag ctgaaactca gcgggctggt caggcctcga 270000 ggactgccca ggccacatga ggtgggcaac aggggctctg gggcaacctg ggggtcacgc 270060 tggagttctc cctctctgga cagtggtggg tgattgggcc cacgcagaca ggccccggag 270120 attcaggact gcaccccatc catggccctg aatgggaccg accctgttga gtaatgggcc 270180 atctcagtgg tacctccttg agcctggtag ggggaggcac tgtttcaatg cagttgaatc 270240 aaggctgagc tctggctggt gcctggtggt gctgcaggca gccctggggg ttgtggtctt 270300 tgggacaagg ggccagctca cgtccctctg gggtctcccc ttccttgaga ttcagtggcc 270360 gaaaggatgt cctcctgagg tgggaagtcc tgctgtcgag ggacctgttc tgggaatttg 270420 ccacacaggc tgcttctgag ccacggggtc acctccaggg tggtagggtc ttgatcccaa 270480 ggaaaggaga ggacaccatg tggtttctta ttgaccaagt gggacctggc tctgtgtgtg 270540 ggaggtgtag ggcaagatga ggacccacca gagaaagtac gtggccctgg aggcccccag 270600 gctttgattt ctggtgtgtg cttggagagg gcaccagggt gggcacccac catgcccagg 270660 gtaggctctg caatggccag gtctgcattg gctcctggtg ttagggccag actcgctggt 270720 tggccatgag caggttggtt gccctcaccc gtccccatag tcccagtgcg gccctggggt 270780 tgttcggggg agccggcccg agcagtggag gtgctgttgg ggcctgcagt agggcatctt 270840 gccccagccc agtgacccac cttccctgtc tttccaaggt ttggtggcca gcagggccaa 270900 tggtgccctg tgtctgtgat gagtcagtgt tcttcatgga ttccatcaca tgggtatccc 270960 ctacccacat tcccctcgct catatgtgag gccctggttg gacacatgtc cttctcctgt 271020 caccacccca gatggtgagc ctggaggaag acttgtattg ggaccctaca ggccccaggc 271080 cagtgtctgt cagcctggtg ctcatccccc agtgcgctga agctcagacc ctccctggca 271140 ccctggtctc ctgcactgag ctgtggtgag cacatccagg ttctgctgga tgcatgcatg 271200 gggagggcct tgattgggtc aatgatgaga accttatatt gtcctgaaga gaggtgatga 271260 cttaaaaatc atgctcaata ggattacgct gaggcccagg ctaggtgaga attttggaag 271320 ggagcgctgg gatgccaaga tccccggcag ggccactagc cactgtattt tatactgaag 271380 aacttgaggc cccaaagggc atctcagggg tcctagccct gtctctgtgc ccctccgtga 271440 ggcagcccag gctccctgtg ttgacttggt gtccaggctc tgcttcctgg ggatagggca 271500 tgttggcagc tccttcctga gcccacgttc tcccctgtgt cttctattga gctcttctgc 271560 ccaggtgggg cccatgccct taagcagtat aggtgagtgt atcctgttgc ggtcatgggc 271620 cataaatgag gcagtgtggg gtcatcgagg gtcagccttc aggccactag cgttttctcc 271680 aggtgccccc ggggagggaa cattgctcca gtagggtcac ttccttggga atctgaccct 271740 aggagcacgc atttcctgaa gccctgcaaa ggtgatggtg gtccaggcag gaaagcgttc 271800 cttcagccca acatacagca gctcccagct gaaatttggt gggctcgtca ggccttgagg 271860 actgcccagg cttcatgatg ggggacacag aagctctggg gctccctggg gctcacactg 271920 gagttctccc tccctgaaga gtggtgggtg attgggccca cagtcaggtg gcggagattc 271980 aaggaatgcc cccacccctg gccctgaatg ggaccaactc tgttgagtaa tgggccatct 272040 taatggcgcc tccttgagcc tgttgggggt gggttgctgt ttcaataagg ttgagtcaaa 272100 gctgagctct gactgggcgc ctggtggtac tgcaggccgg cccttccttg ggccaagggg 272160 gcagcttgtg tcccgctggt gtcatccctt ccttgaggtc cagtggtgga aagggtagcc 272220 tcctatggtg ggaaggcctg ctgctcaggg acctgtcctg gaaatttgcc atccaggctg 272280 cttctgagcc atggggtcac ctccagggta gtggggtctt gagtccaaga aaaggagagg 272340 acaccatgtg gttcctgatt ggccaaggct ccttggttgg ccaggagcag gttggttgcc 272400 ctggcccatg ccccatggtc ctggtgtggc cctggggttg ttcaggggag ctggcccagg 272460 ccgtgaaggt gctctcaggg cctgcagtag agtgcagccc aggcatcttg ccccagccca 272520 gtgacccact taccctgtct ttctaaggtt tggtggccag gagggccaat ggtgccttgt 272580 gcccatgttg ggtcagtgtt ctgcatggat ccccatcata tgggtattcc ctacccaccc 272640 tccctgcact gatatgtgag gccctggttg gacacatgtc ctcctcctgt cccttcagat 272700 ggtgagtctg gaggaagact tgtgttggac ccccacaggc cccaggccag tgtccatcag 272760 cctggtgcta atcccccagt gctctggagt ttggaccctc cctggcaccc tggtctcctg 272820 cactgagctg tggtgagcac atggatgcat gcttggggtg ggggttgccc ttggttgggt 272880 caatgatgag aaccttatat tgtcctgaag agcggtgatg acttaaaaat catgctcaat 272940 aggattacgc tgaggcccag cctaggtgag aattttggaa gaggacactg ggctccccgg 273000 aatggccact gtattttgcg ctggacacct gcaggccctg agggccatct ggaaggtcca 273060 accctgtctc tctgctcctc caggaggcag cccaggctcc ctgagggggc ttggtgtcgg 273120 gctcctgttc cccggggttg gggccggttg gtggctcctt cctgagcccc cattctcccc 273180 ttgtgtcttt cagtgagctc ttccacccgg gcgggccccc ggcattgact ggcataggtg 273240 agtggatcct gcttgtgtca tgggccatga accggtccat gtggggtcac caagggtcag 273300 cctttgggat aagagggttt cctcagggaa ccaacctgaa ttcccatcag agaggtatgg 273360 gttctccagg agggccgctt ttttgggaat tggacccaag gaggataact tccctgatct 273420 ctgcaggagt gacggtggtc caggcaggaa agagttcctt cagccccacc cagcgcagcg 273480 ttctgttgag actcagtgct caggtcaggc ctggaggatt tctcaggcca tctgaggggg 273540 ttagagggga gctctttgtc catggagtgt ggtgcttgaa tctgcccttg gggttgggtc 273600 atggagattc aaggatggtg cctcacccat ggccctgatt ggaattgtcc attgagaaat 273660 acgccattcc agtgggcctc ctggagcctg atggggggtg gtgttttttt ccctggggtt 273720 gagtcgttga tggggactca ccatagaaag catgtggctc tggaggcccc caggctttga 273780 tttccagtgc ctgcttggag tgggcaccag ggccggcacc caccatgccc aagggcaggc 273840 tctgcgactg ccaggtctgc attggctcct ggcatcagga ccagcctcct tggttggcca 273900 tcagctgctt ggttgccctg gcccatgccc cgtggtcctg gtgtggccct ggggtggttg 273960 agtggagctg gcccaggcag tggaggtgct cttggggcct gcagtagggt gcagcccagg 274020 catcttgcct gatcccagtg acctgcttgc cctgtctttc caggattttg tggcagggag 274080 ggccaagggt gccctgcatc cgtgatgggt cagtgttcca cgtggatccc attacgtggg 274140 tccatagagg atgagcatgc gtgagccagc gcccccttcc cacttcttct catggagctg 274200 tgaggccctg tgtggacagc tgtcttcctc ttgtcccacc aggtggtgag cccggaggag 274260 gacttgcgtt cggcccgctg gtcccagtgt gtccggaatt ggtgggttct tggtctcact 274320 gacttcaaga atgaagctgc ggaccctcgc tgtgagtgtt acagctctta aggtggcatg 274380 tctggagttt gttccttctg atgttcggat gtgttcggag tttcttcctt ctggtgggtt 274440 tgtggtctcg ctggcttcag gagtgaagct gcagaccttc gcggtgagtg ttacagctca 274500 taaaagcagt gtggacccaa agagtgagca gtagcaagat ttattgcaaa gagtgaaaga 274560 acaaagcttc cacagtttgg aaggggaccc aagtgggttg ccactgctgg ctggggcagc 274620 ctgcttttat tctcttatct ggccccacac acatcctgct gattggtaga gctgagtgat 274680 ctgttttgac agggcgctga ttggtgcgtt tacaatccct gagctagaca caaaggttct 274740 ccatgtcccc actagattag ctagatacag agtgttgaca caaaggttct ccaagtcccc 274800 accggagtag ctagatacag agtgtctatt ggtgcattca caaaccctga gcttgacaca 274860 gagtgctgat tggtgtgttt gcaaaccttg agccagatac agagcgcgga ttggtgtatt 274920 tacagtccct gagctagaca taaaggttct ccaaggcccc accagagaag ctagatacag 274980 agtgtcgatt ggtgcattca caaaccctga gctagacaca gggtgctgat tggtgtgttt 275040 acaaaccttg agctagatac agagtgccga ttggtgtatt tacaatccct gagctagaca 275100 taaaggttct ccaaggcccc accagactca ggagcccagc tgtcttcacc cagtggatcc 275160 cgcactgggg ctgcaggtgg agctgcctgc cagtcctgcg ccatgcgccc gcactcctca 275220 gcccttgtgt ggttgatggg actgggcacc gtggagcagg gggcggcact cgtcggggag 275280 gctctggctg cacaggagcc catggagggg gtgggaggct caggcatggc aggctgcagg 275340 tcccgagccc tgccccgagg gaaggcagct aaggcccggt gagaaatcaa gtgcagcgcc 275400 ggtgggctgg cactgctggg ggacccagta taccctctgc agctgctggc ccgggtgcta 275460 agcccctcat tgcctggggc cggcagggcc ggcccgctgc tccgagtgtg gggcccgcca 275520 agcccacacc cacccggaac tccagctggc ccacaagcgc cccgcgcagc cccggttccc 275580 acttgcgcct ctccctccac acctccctgc aagctgaggg agcaggctcc ggccttggcc 275640 agcccagaaa ggggctccca cagtgcagca gtgggctgaa gggctcctca agtgccacca 275700 aagtgggagc ccaggcagag gaggcgccaa gagcaagtga gggctgtgag gactgccagc 275760 acgctgtcac ctttcatcag gacagtgtct gtcagccagg tgcacagccc ttggtgtgct 275820 ggagcttggg cttttcttgg cagcctggtg tcctgcattg agcggtggtg agcttgtcca 275880 ggtcccgctg gttacctgca cggtgacggg ggtgccctcg gttaggttga tgatgagaac 275940 cttattttgt ctcgaggaga ggttatgtga tgggtgttgt ggcagctctt tgtatttcat 276000 tttcttcagt gctttttgtg tgttctcttt gtatttttta ccgctttgtg tattttactt 276060 tcacaaaggc agcagcaaat gttttattgg tggtggtatt tttcattttt atttacttcc 276120 taatttgata gtgttttagt tggaatacac agtctcattg tagttgttca gaaatatgct 276180 ttttttctgt acattatatg attgtgcata atttttgcca gttttttttt taattgggga 276240 ctacagttga atgcactgcc tatctcctac tttactgaaa cagattgtat ggaaatctaa 276300 agacgagaaa gtagacaagc acagcagagg acatttattt tgatataacc acagaaattc 276360 attgatatga ccttatcata ttgatggttt ttcaaagaaa tataaaatct ttcgataatg 276420 gattgtctca gttgcgtttc tccttatatc atgttttgcc ttcaatacaa attgcaatgc 276480 ttagaaattt aaagaacacc ttctgaagtg gaagatctag ctaaagaatt agattggtat 276540 tggctgaaat gttgcagtaa tcacatgata gggttaatac aacatgagtt acatgctgag 276600 tgctctaagg tagaaagtag gtaacaagga ataacaggta ggtaatgtaa gtcgggagaa 276660 ggaaactcta ggacagaatc attagaaaag gcttgacgtc aacagcagtg tatagaattt 276720 acagtgtata gaatttacag tgcatagaat ttacaataag tgcctttttt tgtgctcatc 276780 aatgctcttg cttatattgt aggaggagtt agttcccttg aagaaatatc aatacaaatt 276840 tccaaattgc aatgcagagg gaaaaaagaa tgagaaagta aaaaatatcc aagaactctg 276900 gaagcatttc aaaaagtgta aaaatgcata gtgacaatgt caggagaata aggagataaa 276960 ggaaaagaaa tatttgacac aacaatgact tgagcacttt ctaaaattaa tgatggacag 277020 aaacccacat gttcaggaag ctcagagagc actctgcaga ataaaaatat tttacaaatc 277080 gacacctttg catttcatat ttaaagtcca gaaaatcata gactaaggga aaagcttgat 277140 aggagcaata ggaagaaaac catcttacct atggagcaac aagaataaaa attgctttga 277200 aattatcttc agaatccatg aaagcaagaa gtgagtcagg gtgaaatatt tagtgttaaa 277260 agtaagaaac aaaaaaaagt accaactttg aattttctgc tcatcaaaat tattcttcaa 277320 aagtgaagga gaaatactct ctgagaccaa caaaaattgc tagaacttct tgccactaca 277380 ccaacctttt aataaacgta acaagaaatt cttcagaaag gataaaaatg acataggtcg 277440 gaaaatctaa tttacataaa gaaatgaaaa gcattggaga agaaatatat gaagaaaaat 277500 taaatatata tgtatttttt gattcataat tgatctttca acaatttgtt caaaataata 277560 acaagattat atttggtgat tataggttat ggaaaagtga aatgaatgac agcaatatta 277620 taagtcatcc ggttccaaga tggccgaata ggaacagctc cagtttacag ctcccagtgt 277680 gagtgacgca gaagacagtt gatttctgca tttccaactg acgtaccagg ttcatctcac 277740 tggggcttgt tggacagtgg gtgcagccca tggagtgtaa gccgaagcag gacgaggcat 277800 cacctcacct gggaagtgca agaggtcagg gaattccctt tcctagccaa gggaagcgtg 277860 acagatggta cctggaaaat tgggacactc ccaccctaat actgtgcttt tccaactgtc 277920 ttagcaaacg gcacaccagg agattatatc ccgtgcctgg cttggagggt cccacatcca 277980 cggagccttg ctcactgcta gcacagtagt ctgagatcaa actgcaaggc agcagtgagg 278040 ctgggggagg ggcatccacc attgctgagg cttgagtagg taaacaaagc ggctgggaag 278100 ctcgaactgg gtggagccca ccacagctca aggaggcctg cctgcttccg tagactccac 278160 ctctaggggc agggcatagc agaacaaaag gcaacagaaa cttctgcaga cttaaacatc 278220 cctgacagct ttgaagagag tagtggttct cccagtacag agtttcagat ctgagaacag 278280 acaggctgcc tccttaaatg ggtccctgac ccccaagtag cctaactgag agacacctcc 278340 cagtaggggc tgactgatac ctcatacagc tgggtgcccc tctgagacga agcttccaga 278400 ggaaggatca ggcagcaaca tttgccgttc tgcaatattt gctgttttgc agcctccact 278460 ggtgataccc aagcaaacag ggtctggagt ggacttccag caaactccaa cagacctgca 278520 gctgaggatc ctgactgtta gaaggaaaac taacaaagag aaaggacatc cacaccaaaa 278580 ccccatctgt acgtcaccat catcaaagac caaaggtaga tgaaaccaca aagatgggga 278640 gaaaccagag cagaaaaact gaaaattcta aaaatcagag cacctcttct cctccaaagg 278700 aatgcagctc cctgccagca atggaacaaa gctggacgga gaatgacttt gacgagctga 278760 cagaagtagg cttcagatga tcgctaataa caaacttctc tgagctaaag gatgaggttc 278820 aaacccatcg caaagaagct aaaaaccttg aaaaaagatt agatgagtgg ctaactagaa 278880 taaacagcat agagaagacc ttaaatgacc tgatggagct gaaaccatgg cacaagaact 278940 acgtcacaca tgcacaagct tcagtagccg atttgatcaa gtggaagaaa gggtatcagt 279000 gattcaagat caaatgaatg aaatgaagca agaagagaag tttagagaaa aaagagtaaa 279060 aagaaacaaa gcctaaaaaa gtaaaaaagt aaaacaaagt aaaaaagaaa catgggacta 279120 tgtgaaaaca ccaaatctac gtctgattgg tgtacttgaa agtgatgggg agaatggaac 279180 caagttggaa aacactctgc aggatattat ccaggagaac tcccccaacc taggaaggca 279240 agccaacatt caagttcaga aaatacagag aatgccacaa agatactcct tgagaagcgt 279300 aactccaaga cacataattg acagatacac caaagttgaa atgaaggaaa aaatattaag 279360 ggaagccaga gagaaaggtc aagttaccca caaagggaag cccatcaaac taacagcaaa 279420 tctctcagca gaaactctac aagccagaag agagtggggg ccaatattca acattcttaa 279480 atgaaagaat tttcaaccca gaatttcata tccagccaaa ctaagcttca taattgaagg 279540 agaaataaaa tactttacag acaagtaaat gctgagagat tttgtcacca ccaggcctgc 279600 cctacaagag ctcctgaagg aagcactaag catggaaagg aacaaccagt accagccact 279660 gcaaaaacat gccaaattgt aaagatcact gatgctagga agaaactgcg tcaactaacg 279720 agcaaaataa ccagctaaca tcacaatgac aggatcacat tcacacataa caatattaac 279780 cttaaatgta aatgggctaa attctccaat taaaagacac agactggcaa attggataaa 279840 gagtcaagac ccatcagtgt gctgtattca ggagacccat ctcatgtgca gagacacaca 279900 taggctccaa ataaagggat ggaggaagat ctaccaagca aatggaaaac aaaaaaaagc 279960 aggggttgca atcctagtct ctgatgaaac agactttaaa ccaacaaaga tcaaaagaga 280020 caaagaaggc cattatgtaa tagtaaaggg gtcaattcaa caacaagagc taactatcct 280080 aaatatacat gcacccaata caggagcacc cagattcata aagtaagtcc ttacagacct 280140 acaaagagac ttagactccc acacaataat aatgggagac tttaacaccc cactgtcaac 280200 attagacaga tcaacaagac agaaagttaa caaggatatc caggaattga actcagctct 280260 acaccaagca gacctaatag acatctacag aactctccac cccaaatcaa cagaatgtac 280320 attcttctca gcaccacatc gcacttattc caaaattgac cacatagttg gaagtaaagc 280380 actcctcagc gaatgtaaaa gaatagaaat tataacaaac tgtctctcag accacagtgc 280440 aatcaaacta gaactcagga ttaagaaact cactcaaaac cactcaacta catggaaact 280500 gaaaaatctg ctcctgaatg actactgggt acataatgaa atgaaggcag aaataaagat 280560 gttctttgaa accaatgaga acaaagacac aacataccag aatctctggg acatatttaa 280620 agcagtgtgt agagagaaat ttatagcact aaatgcccac aagagaaagc aggaaagatc 280680 taaaattgac accctaacat cacaattaaa agaactaggg aagcaagagc caacattttc 280740 aaaagctagc agaaggcagg aaataactaa gattggagca gaactgaagg agatagagac 280800 acaaaaaacc cttcaaaaaa tcaatgaatc caggaactgg ttttttgaaa agataaacaa 280860 aattgataga ccactagcaa gactaataaa gaagaaaaga gagaagaatc caatagatgc 280920 aataaaaaat gataaagggg atatcaccac caatcccaca gaaatacaaa ctaccatcag 280980 agaatactat aaacatctct atgcaaataa actagaaaat ctagaagaaa tggataaatt 281040 cctggacaca tacaccctcc caagactaaa ccaggaagaa ggtgaatctc tgaatagacc 281100 aataacaggc tctgaaattg aggcaataat taatagccta ccaaccaaag aaagtccagg 281160 accagaggga ttcacagctg aattctgcca gaggtacaaa gaggagctgg taccatgcct 281220 tccgaaacta ttccagtcag tagaaaaata gggaatcctc tctaactcat tttataaggc 281280 cagcatcatc ctgataccaa agcctggcag agacacaaca aaaaagagaa ttttagacca 281340 atatccctga tgaacatcga tgcaaaaatc ttcaataaaa tactggcaaa ccgaatccag 281400 caacacatca aaagctaatc caccacgatc aagttggctt catccctggg atgcaaggct 281460 ggttcaacat acacaaatca ataaacataa tccatcatat aaacagaacc aaagacaaaa 281520 accacatgat tatctcaaca gatgcagaaa aggcctcgac aaaattcaac agcgcttcat 281580 gctaaaaact ctcactaaac taggtgttga tgggacgtat ctcaaaataa taagagctgt 281640 ttatgacaaa cccacagcca atgtcatact gaatgggcaa aaactggaag cattcccttt 281700 gaaaactggc acaagacagg aatgccctct ctcaccgctc ctattcaact tagtgttgga 281760 agttctggcc agggcaatca ggcaggagaa agaaataaag ggtattcaat taggaaaaga 281820 ggaagtcaaa ttgtccctgt ttgcagatga catgattgta tatttagaaa accccatcgt 281880 ctcagcccaa aatctcctta agctgataag caacttcagc aaagtctcag aatacaaaat 281940 caatgtgcaa aaatcacaag cattcctata caccaataac agacaaacag agagtgaaat 282000 catgagtgaa ctcccattca caattgcttc aaagaataaa atacctagga atccaactta 282060 caagggatgt gaaggacctc ttcaaggaga actacaaacc actgctcaac gaaataaaag 282120 aggacacaaa caaatggaag aacattccat gctcatggat aggaagaatc agtatcgtga 282180 aaatggccat actgcccaag gtaatttata gattcaatgc catccccatc aagctaccaa 282240 tgactttctt cacagaattg gaaaaaacta ctttaaagtt catatggaac cgaaaaagag 282300 cctgcattgc caagtcaatc ctaagccaaa aggacaaagc tggaggcatc acactacctg 282360 acttcaaact atactacgag gctacagtaa ccaaaacagc atggtactgg taccaaaaca 282420 gagatataga ccagtggaac agaacagacc cctcagaaat aataccacat gtctacaacc 282480 atctgatctt tgacaaacct gacaaaaata agaaatgggg aaaggattcc ctatttaata 282540 aatggtgctg agaaaactgg ctagccatat gtaaaaagct gaaactggat cccttcctta 282600 caccttatac aaaaattaat tcaagatgga ttaaagacct aaatgttaga cctaaaacca 282660 taaaaaccct agaagaaaac ctaggcaata ccattcagga cataggcatg ggcaaggact 282720 tcatgactaa aacaccaaaa gcaatggcaa caaaagccaa aataaacaaa tgggatctaa 282780 ttaaactaaa gagtttctac acagcaaaag aaactaccat cagagtgaac aggcaaccta 282840 cagaatggga gaaaattttt acaatctact catctgacaa agggctgata tccagaatct 282900 agaaagaagt taaacaaatt tacaagaaaa aaatcaaccc catcaacaag tgggcaaagg 282960 atatgaacag acacttctca aaagaagaca tttatgcagc caaagacaca tgaaaaaatg 283020 ctcatcatca ctggccatca gagaaatgcg aatcaaagcc acaatgagat cccatctcac 283080 accagttaga atggcaatca ttaaaaagtc aggaaacaac aggtgctgga caggatgtgg 283140 agaaatagga atacttttac actgttggtg ggatggtaaa ctagttccac cattgtagaa 283200 gacagtgtgg caattcctca aggatctaga actagaaata ccatttgtcc cagccatccc 283260 attactgggt acatacccaa aggattatat atcatgctac tataaagaca catgcacatg 283320 tatgttcatt gtggcactat tcacagtagc aaagacttgg aaccaactca aatgtccatc 283380 aacgatagac tggattaaga aaatgtggca catatacacc atggaatact ttgcagccat 283440 aaaaatggat gagttcaagt cttttgtagg gacatggatg aagctggaaa ccatcattct 283500 cagcaaacta tcgcaaggac aaaaaaccaa acactgcatg ttctcactca taggtgggaa 283560 ttgaacggtg agaacacttg gacacagggt ggggaacatc acacacgagt ggctgccgtg 283620 gggtgggggg aggggggagg gatagcatta ggagatatac ctaatgtaaa tgacgagtta 283680 acgggtgcag cacaccaaca tggcacatgt atacatatgt aacaaacctg cacgttttgc 283740 acatgtaccc tagaacttaa agtatgaaat atatatatat atatatatat atagtcatga 283800 gggagagaaa atactcttag ttacttggac taacccacga agtaggacag tataatttga 283860 aaaaggactt ggattagttg taaacgtata atgtaatatc cagcacagcc actaaaaatg 283920 attttgaaaa aagcagtata atcaatatac taacagaaga aaaagcagaa tcaggccaga 283980 catggtgact catgtctgta atcccagcac tttgggatgc tgaggcagga agatcacttg 284040 agccccggag ttcaagtcca gcctggcaac gaataagagc ccatctctac cctccacccc 284100 ccccaaaaaa aaaaagaaaa agaaaaagag gccgggcacg gtggcttact cctgtaatcc 284160 cagcactttg ggaggccgag gtgggtggat cgcgaggtca ggagatcaag accatcctgc 284220 ctaacacggt gaaaccccgt ctctactaaa aatacaaaaa aaaaaaaaaa atagctgggc 284280 atggtggcgg gcgcctgtag tcccagctac tcaggaggct gaggcaggag aatggtgtga 284340 acctgggagg cagagcttgc agtgagccga gattgcgcca ctgcactcca gcctgggaga 284400 cagccgcaag attctgtctc aaaaaaacaa caacaacaac aaaaaaaaac aaaaacaaaa 284460 acaaagaaaa cgaaaagaaa aagcagaatc tttttttttt tttttttttt tttttttttg 284520 agatggagtt ttggtcttgt tgcccgggct ggagtgcaat ggcacgattt cagctcacca 284580 caacctccac ctcccaggtt caagcaattc tccgggctca gcctcccgaa tagctgggat 284640 tacaggtgtg caccaccatg cctggctaat tttttgtatg aaaaagcaga atcttataca 284700 atgctcaatt aaaatcaggg agaggagaaa aagagtagaa taccaaaaaa gtaacaaatt 284760 acaaggttga tataaataga aaacaatcac aaatactgag tatactaatc taagtatatc 284820 aataatcact ttaaacatcg cttaaaagac agagattgtc agtggattaa gaacaagacc 284880 caaatatatg ttgtctatga gaaatgcact ttaaatagct gggcatggtg gtgtgcacct 284940 gcagtcctta ggaggccaag gcggagtgtc acctgagccc aggattttgg gactacagtg 285000 agctatgatc atgccactgc actctagcct ggttgacaga ataagacctc atctctatag 285060 aaaaaagtaa gtaaatctac tttataaagg cacaaatata ttcacagtaa aggaatagag 285120 aaagatatcc catgctaaca ttaatcaaaa taaagtgaaa tagccatatt aatttcagac 285180 acaaccgact ttagaacaag gaatattatc agagatcaaa agggacattc cttaatgata 285240 aagggatcag ttttctaaga agacataaca atccttaatg tgtacgcact gaacagcaga 285300 tcatcaaagt acatgaagct aaatctgata gaactgcata gagaaataga taaattcact 285360 cttagagttg gaggcattgg catccctcta tcagaaatgg acaggtttag caagcagaaa 285420 atcagtaagg gcataacatg atcaatcatg atcaaaaact tgattcagtc aactatatgt 285480 aactgacatc tatggaccac tttacccaac aacagcagat gacacatttt ctcacacaca 285540 catgaaacat tcagcagaat agaccacatt ctgggctaga aaatgcacct caacaaattt 285600 aaaagaatag aaatcataca aagtatgttc tcagactaca atggaatgaa agtaaacaaa 285660 aatcactaaa aaagatagct gaaaaacatg aaaatacttg gaggttaaac aacagactga 285720 aataactgaa ggtcacagaa gtctcaagat aaatttttaa aatatttcaa actaaatgga 285780 attgaaagca caacttatca aaaatttagg aacgcaacaa aggcagtgcc tactgggaaa 285840 tttataccac tgaatgtatg ttaaaaagaa caaagatcta aataaataat ccttcccatt 285900 ggaaagctag ggggaaaatt caaattaaat tcaaagtaag caagtaaaag aaataataaa 285960 atatgaatac aattctgagt ggcctgatat ctgatttctg gaagctgagt tttatgtggc 286020 tttagaagtt tcatgttatg agtgtgaaat ggcaagtgac catggcgatt gcttctgata 286080 tggccacctc aattacatag agaagggatg atcagtggca tcatcccagt tctgcatgat 286140 accacaccag tgattctcca aagtcaagaa acctgtatat gttgtccttg tgtttggtga 286200 atctgtggtc tatagactac ataatgggct atttctgggg tactgaccat tttgctccat 286260 taaggaaaac catgcatgag ccatataact atgggaaaca atgttttcct ttttgacacc 286320 tggcctactc tcttcttagg tgagagcaaa ggaagagcac cacttggcct gctgcaccca 286380 gggcaattta taccatccag atatccagca ctgaatatgt agcaactcca atccaccata 286440 gaacattaat ctatctctga taagcatgct aatatctatg attctgcctt tgtggggaga 286500 tgactccata gattaacccc ctggcttggg gcaatatgga gatgttatat tgtcttcgac 286560 agggaagatg acataaaaat tatgttcaat aggattatgt ggagacttaa cataagtgac 286620 aaacctaaga caagaagtta gaaatccttg tttcttttag gtgaataatt ttggagcttg 286680 agaaaaagac accattgtgg cgaacttgct ttgccaaacc ctgtgtatgc atttttgggt 286740 aaacaacaca ttttcatcct ttaagcattg tttccattat ttataattcc taatagtatg 286800 agacatttag gactcattcc ttggttcttc ttctctcatt gtatctttca ttgtatcttt 286860 cagtgctgca agagatgcaa tcatcccatt aatgaaagca gagtgactgc cttcgtcaca 286920 catacattca aaatagatca ctaggctagt gatgattctc tcttaaggct attatgttta 286980 ctcatttaaa aaatctggat ctcagtatag attttcttct cagtgagtga ctgacctatc 287040 tgatatgatg ctatgacaaa atctttactt tttacctgaa tttggtggga ttgaaagttg 287100 agaacatatt aatttatttt ctgtttcact tgattaataa tgcccaatct aacatgcagt 287160 gttcacttgg gtacatatat acaactacat caaatttttt cttgttttac cttaaaagtg 287220 ttaagatatt gtaatggtat ggccagttta ctcactggta aacttttcat aacagaaata 287280 tcatgccagt ggacacaaat atgtaacatc agtaatttgc tttcctcatg aaacagagaa 287340 ctgaataagt tgatgggtaa actagtatct gaattataaa ccccaaatat catgtgactt 287400 catcattttc agtataatga aaatacaggc tgtgaatgct tccagttggt cctgaaaggg 287460 cctttgaggt gagtaggttc accaaagcgg caacatatgt gtcccagtgg gcattctact 287520 cctcagtaag tgacttgaca ttctttatgg cttcctcatg attaaaacaa gtctttttat 287580 tgaaatttta ctgaaataat gatgaaacaa tgtaatattc ttttcatcta catataagag 287640 tagacataga ttaacctcta cctttttttt tttttttttt gagacggagt ctcgctctgt 287700 tgcccaggct agagtacagt ggtgcgatct cagctcattg caacctctgc ctcccaggtt 287760 caagcgattc tcctgcctca gcctcctgag tagctgggat tacaggcacg tgctaccatt 287820 cctggctaat ttttttgtaa ttttagtaga gacatggttt caccatgttg gtcaggctgt 287880 tcttgaactc ctgaccttgt gatctgccca cctctgcctc ccaaagtgct gggattacag 287940 gcttgagccc ccgtgcctgg ccttcacctc tacctattat aatattttca tgttattcca 288000 ttttgtcatg tttgtgggtc atttgatgag ggttcacaat atgaaaactg ggcattttgg 288060 ccaagatgca tgtaaatgaa tacaactcca tgtgccctga taactgattt ctagatcctg 288120 agatgcaagt ggcttccaga gtgtctgtat tttatgaaag ttcatataca gtaaaccatg 288180 ctaattgtta ctgatacagc ttccttgaat atataaagcg atgattaatg ggatgttttg 288240 tttctgcaga aaaccactga attgcttctc caaagccaag tgacctgtat gatttgtcct 288300 tattatattt tgtgaaccag tggactaaaa cctttataat gggtcatttt tttagtattg 288360 tcaatattgc tcaattaaca aacatgactc atatacacag gtgagatgta gttctccctt 288420 tgacatttgc tctacatctg tcccttagat gatgatatgg aagaaaagca ctctttggcc 288480 tgttgtgact gggacagttg acagcaccca ggtgtccttt aatgaaaatg ctcttgacac 288540 caatgcatcc tagcatcaca gcttcaggaa gccttctcaa gtgtgcatgg ggagtactat 288600 gtctttcatc aataatgaaa tcttctgatt tggtgagaaa taatgcctta aaattacact 288660 caataggatt atgctgaggc tcagcctacc tagatgaaaa tgctgaaaca gataatagtg 288720 acttcttatt tcccttcaag gggaatttta ttttgaactt gaaataacaa aatctttatg 288780 ggtaacttgt ttgcccaact gtatcagtgc acctataaat gaacaaaaaa ttctcagcct 288840 ataagctttg cttcagtgac ctttaatttc taatagtaag gtatattcag gtctcattct 288900 ttggcttttt ctcttattgt gtatttcagt aagacatgct gccaagagat gtgccattct 288960 attataaaag atcagtagct tcctttaccg acgtgtatat tctatctaga acattgagct 289020 atggaagact cccacctaag ggaattagtt ttacaccttc aggtaatctg aacttcaata 289080 tgagttttgc tttatgatat aatccttatg acaaaatctt tactttttat ctgaacttca 289140 tacaatcaat attgaagatt ttttaaattc actgttacct agtccaatat ttaatataca 289200 tttggctgta gatacatgac tagacaaaaa ttttttatat tattattgtg ggggctctaa 289260 cagtgtttca ctgttttgag ttactgatga actttctgta actgtgagac catggtaatg 289320 gaagagaccg tggtaatggg gaggagaatg tgaggatcag tatgtacttt gcctataaaa 289380 cttaaatatt tagtaatttg atcaccaaat tgatactcaa atttcagttc ctatcatgtg 289440 taaaccaaaa agtatctgag atttagaagt ttatttagaa gtggattttg ccaaggttaa 289500 gcacatgctc agaagaaata aacccaaaat cacagaaacc gtctggggtc tatgtctttc 289560 tccaaagatg attttgaggg cttcagtgtt taaaggggaa aagtgggctg gagggggaaa 289620 agggagggta tgataatccg tatgttccaa gacaaaagga gcaggtaggg gtatagtcaa 289680 taatgtattc atctcatgct cagtaaatca gcactttaca taagataagg tgaacataga 289740 gaagctacct gtggagatct ttaaccttta atctgtagct atctgcttaa gatcaaaagg 289800 aaattcttgc atgactcagc tttcagctta tttttttttt ctcttggcgt agtaaattgg 289860 ggtcccaagt ttattttcct ttcacacatg tgaccccact attttcagaa taatgaaagc 289920 acatgttaga aatgatgaca cttattccta atatggactt tgaaatgact gggttcacaa 289980 atttagaatc atggatctca ttataggttt ttattttcaa tgagtgactg gcctacttga 290040 tggaattctt tcaaaaaatg ttcacttttt actgagatta tattaaaata atgttggaat 290100 gtgttcagtc atgtttacca tctctatagt atgatatatg ataatatcgc agattactca 290160 gtgtcaaaaa cctggcatac cttgtcctta tgatgttgat gagtcaatgg tctagagcct 290220 tagtaatatg tctttttgtg gtagtacgga ccgtatctgt ccactaagaa atagcctgtg 290280 taagccatat acacatgaac aatttatgtc tgattttgaa ctatggtccc attcctatgc 290340 ctgtagataa agactgctga gaagagcacc ctctggtgtt gtcacagagg caagtgctac 290400 cgcacaggca tgctgcagtg aatttaactg atcctctgtc cctgcaaccg ttgtttaagg 290460 atgctattct ggtaagggtt tacaagacaa cgtaaatata tgtataaaga gtatcttcag 290520 gagacgtaat aatgtaaaaa tcatgctcaa tagaattaag ctgaggctca aaatagtgcc 290580 aatccttgca agaaggtgtg agaagtcatt agatttgggg ggtatgggtt attccatttt 290640 gaacttggta ggaagaaacc cttgggggaa tcttacatca tttgcctcta cctacttcta 290700 aaggaacttt taaaattctt ttatcttgtc tttattctta atactcatac attattagag 290760 agaatatctt ggtttatttt ttcctcatgg tgtgcttcag aatgttcatc cagcaagagg 290820 tgtgtcatta cacggattat atatatgagt tctgtctttc gtaattaaaa aatttcaagt 290880 ggaccatttg aatattaaac attggccttc aaaatgatta catttacctg ttcatacaaa 290940 attagtgagc aatgatctat tctttccaat gagtgactga tctaatgagg tcctcattaa 291000 aactcctttt tttttttttt ttttttttgc ctgaacgtac tttgatttaa agatgtgaca 291060 tttagtaatt cattgcaatc aactctttag tgattgcaca aatagacaat ccttttctat 291120 tattttattt tttggttgct gtgtatggtg ttatgatgtt tgtggatcat tgaggcacta 291180 ctcacaactg aaagactttg gcaattttag ggaatggctt gagattcagc tataggttac 291240 ccttgattga aattgaatac aatacaggta gtctgaaatc tcatttcctt atcctgagtc 291300 tcactcaggt gtcattagat tcattataaa gaaatgcata cactatgtat gatgccagtt 291360 gttactgata tgaagacgat aagaagcttt tatttctgca gggaaataat cccttaccag 291420 gtcatcaaaa gacatgatac ctatgtgctt ggcccttact gtacacgggg aatcagtggt 291480 ctaccacagc ttaagtaacg ggtcatattt ggagtatcac acatctcagt cttgtagaaa 291540 ttaggaacag caattaggag tcatgcacat ataagagatg taatcccacc ctttgactat 291600 agcctactct tgtcttttac agaaaagact gtggaggaag aaaacccttt accctgttgt 291660 tcagggagaa actgacacca ctcaactgcc tggcactgaa aatgtggcat ccagtccact 291720 ttaccatcag tgtttaagga aaccatctct ggtaagcata tttgatccaa gtgtgcatat 291780 gcacatgagt gccatgggct gggtcaatga tgagatgtta ccttgaagag aaatgatgac 291840 gtaaaaatta agttcagttg gattacgctg aggcccagcc taggtaacaa ttgtgagaca 291900 agaagtttgg atttcttagt ttccttccat tggggacttt attttgggat tctggcaatg 291960 gaatcttatt gcgaaacttg ttttgcacgc ttctatctgt gtgcttctaa gtaaactata 292020 aattctgatt ctttaagtgc tatttaagtt tcctacaatt cctaattttc ttggatattt 292080 ggcactaaga cccttgctct ttttctctca ttggatgatt tagtaagtcc tactggcact 292140 attctattga gtggaggtga gaggctgcct ttgctgactg aaaaatttca aatagataat 292200 tgaactagtg aagactgagc tctataataa ttagatttat tcattcagac aacatgaata 292260 tcacgatagg gttttcttct caatgattga ctgacacatg tgatgcaatc ctcatgagaa 292320 aatccttact tttgccctac gattgattgt tttcagggtt gagaaatatg atacattgga 292380 attttgctca atgcgctaca gttatcgtgg tctaaatata cagacaaaat tttctgtaat 292440 gttagtataa tattttaaca gtgctaggat atgttttgat cattaatgaa tctttatgac 292500 ttaagggtcc ttgcaattgg gataaaaatg tgagtttcaa taatatgtgt ttgcccatga 292560 aacttgaaat tagataaatt gatgagcaat ctggtgcctg acttttcttt ctcaagtacc 292620 tttggcttcg ttttcattat gatgaaagtg tgtgctgtga ataatgccaa tggtaaataa 292680 gacctttatg gacacttata tgaatgacag tcagggccgt tccttcaggc cacatgatta 292740 tcgttatgca ttcttcttct caatgagtga ctagcatact tgccaggatc tacaagaggg 292800 aaactttatt ttttactaaa attgcatcga tataatgttg acaagttttg tgattattgg 292860 tatcatctct aagatgtgat gctcatttgg tctaaatata gaagttaaca tattaacttc 292920 taatttatat atgtcaggtt gctatgtttt tacaatgttt gtggtttatt gatgatgact 292980 cacaacataa agactatggc attatggcta catgttctaa ttctgatata tacatatccc 293040 atcattcatt aaattaaata caattatgag tagtatgatg tctgttttct aaaatctgag 293100 tttcacctgg ctccagtatg atcattatat gatggagtgc aagcaacatg ttaatgccaa 293160 ttgttattga tatggcttcc ttgaatatgt aaacaagact gatcaattga aggtcttatt 293220 tctgcattaa actacctgag atattctcca aattcaagag acctgtatag ttagtcttta 293280 ttctgtttga tgaataaatg gcctatagcc tatctaatgg atcagttttt ccagtactaa 293340 tcatatctct tcattaagaa atagcatgca taagccatac atacaggagg taatatttgt 293400 catcttgatc tactgtctta tcctcctccc cttagataag gatgactgag gaagagtact 293460 ctttggcttg ttgacaccag cacagctgac acacccagat atctgtttgg tctcctgtga 293520 actttcaacc aggatttaag gatgccactc tggtaggtat tttcagacaa agtgaatatg 293580 tgattgtaga gttccatggc ttgtttcaac aataagacct tatgttgtct tgaggacatg 293640 agatgacatg aaaactagac tggctggtcc ttatcttttc tggggtattc tagtttgagc 293700 ttaagataaa gaaatatatt tgggatatag tttctctcac ctgtttctat tagcttctag 293760 aagaccactt atcaattctt tcctcctgat ttagtggaaa acattttggc agttcctcaa 293820 aaagttaaag ataaaattac catgtaaccc aacaattctg ctcctaagta cacactcaaa 293880 agaattgaat acaaatgttc aaatgaatac atacacatga atgttcatag cagcactatt 293940 cactggctgg agttccagac cagcctggcc aacgtggcaa gaccctgtct ctactaaaaa 294000 tagaaaaatt agctgggcat ggttgctcac gcttgtagtc tcagctactc aggaggctga 294060 ggcacaagaa tcacttgaac ccaggaggca gaggctgcag tgagctgaga tcacaccatt 294120 gcactccagc atgggtgaca agtgagattc tgtctcaaaa aaaaaaaagt gaaggtatga 294180 tgacaatgtc acacaaaata gtgaatacca ataaaaagat agaaattatt aaaaagaacc 294240 aaatgaaaat tctggagttg aaaagtacaa taactaaaat ttaaaaattt attagaaagg 294300 ctcaatagta gatttgaact gggagaagaa acaagaagta aacttgaaga tagaacaata 294360 gagattatgt tcaaaagaac agaaagcata aagaataaag aaacaaagag agtctcagag 294420 aatgtggaac atcattaagc ataccagcat acacatatgg gagtaccaga caggcagggg 294480 agatacaaag gatcagaaaa aaatatttga aggaataatg gctgaaacct cccatatttg 294540 tggaaaacaa taactgacat atccaggaag ctcaatgaat tccaatgaat aaatgcaaag 294600 attgacaaat ggaaacatca cagtaagata tctgaaagtc aaaaacaaga agaaagtctt 294660 gaaagcagtg tgagaaaaat gatttgttac ttacaaggga accccaggaa gattaacagc 294720 tgacttcagc agaagcaatg gaggccagaa gcaaaggcat aacatattaa aaatgctcaa 294780 agaaaaaaga acctgtcacc taagaattct gtacctggca aagctgtctt tcaaaaatga 294840 aggcaaaata aagacttcct caattaaaaa aaaaaaagtt ggagaatcta ctgctctcaa 294900 aaccccctta aaagagttct ctaaatactt aaagaagtta ttcaagctga aagcaagtga 294960 gcctaggtag ttattcaaat caacaactac aaagcaaatg cttgtaaagg taattatata 295020 aatataaaag acagtagaaa tgtaattttt ctctgaagtg attttaaaat aaattctata 295080 aaataatatg tatataatgt attttggggt ctataacata taaaagtgta atatatttgc 295140 caaagaagat aggtggatgc aaagcaatac aagactaagg aaatgactac agatggtaga 295200 ttaatattta ttataatgtc tttcttggct tatagcatca ataaatgtaa tatgtataat 295260 aataccacaa aagatggcaa aaagggaata gagctatata ggtgtaacat ttctgtataa 295320 gactgaaatt aagctagtgt aaattagaaa cttatttggg tgagttaaga tatatgcagt 295380 aaaccctaga gcaaccactg aaaaaattca aaacatatag tgaaaaaaat tattaaggaa 295440 gtttaaatgc tacattataa aataattact taatgaaaaa gaagtaaaga ggaatagagg 295500 aacaaaaaca catgagacac agaggagaag aagaatgaca taataaactc aactaaataa 295560 taaaattaca tgtgaataca gtaaatatgt aaattaaaag gcagagattc ccaggctgga 295620 taaaatctcc aggtttaata tccctttgcc ccaaataaac tccagctttt tttcctatga 295680 tgtatttgat cattgtgctg gtttacaaaa gatttctaac ctttctaaaa tctttaaaat 295740 cagcggcgaa gtgttctatc tcatttcacc catatatatc agagactcaa atcctgaaaa 295800 ataccaagtt gacctgccca ttcttgagtt ctgctgaatg gtgtgttccc agatcactat 295860 ggatattgct gtttacttga ccaattactt ttagtcaaca agatttgaac aatgcttttg 295920 attcacacag cgtgagacct agacttccct catattgaaa taggagcatt agcatcctgg 295980 attcctgcac cggcttttga accttatgtt tcctgcaccc caagaagcca tgttatctgg 296040 acattgtcct ctctgtgatg ggaaagaaga gttttttcaa caaatgttgc taggacaact 296100 ggatatctag atacaaaaga tactgcattt atgttaccag ttttctgtgt cagtccattt 296160 tgctctgatg taacagaata ctgcagactg ggtatttgta atgagtggaa acttattggc 296220 tcacatttct ggaggctgga aagatcaagg ggctggcata tgataagggc cttctcactc 296280 tgtcatccta tggtagaagg gcaaagagag ggtatggatg ggacaaatat cttcttttat 296340 aggaacccac ccctgaaata acagcattaa tccattgatg agggcagagc tctcacagcc 296400 taatcacctt tttttttttt ttttgagacg gagtctcgct ctttcgccca ggcgagagtg 296460 cagtggtgct atctcggctc actgcaggct ccgcctcccg ggttcacgcc attctcctgc 296520 ctcagcctcc cgagtagctg ggactatagg cgcccgccac ggcggccggc taattttttg 296580 tatttttagt agagacgggg tttcaccgtg ttagccagga tggtctcatt ctcctgacct 296640 cgcgatccgc ccgccttggc ctcccaaagc cctgggatca caggcgtgag ccaccgcgcc 296700 cggccgccta atcacctttt aaatgttgct ttattaaaca ctgttgcatt gagggttacg 296760 tttccaagac aggcttttga agtgaaatga aaaatttgac cattcccaat tatagtttga 296820 aatttcaatg ctcctttctt agtatgtgat tgaacatgga taagataatc agtaacggtg 296880 gatgtaagaa cactattaac caacttgact ccactgtcat atgtagaaca caacacccaa 296940 caatagcaga atgcacatta tattcaagtg ctcataaagc attattttgt atatatgtat 297000 tttctccctt ttttgataaa gttagctagt agagtgccta tgtagttaat attttttaaa 297060 aaccacaggc ttctcaatta ttaattacat ctatggtttt taaaatatta tcttcattaa 297120 tttctgcttt gatccttatt cctttctttc ttgtactttc ttttattttt gttctttttt 297180 agtgttttaa gatgaaaatt gaattgtttc attcatcttt ttcatttttt aaaataaaaa 297240 catttagtgc aatgaatttt cctctagaac tgcctttaaa tgcatattac agattctcat 297300 atgttgtata ttttaaaata atatgtaaat atatatttgc atagaaaaac atatttacat 297360 acaaaatatg tatttacata tttaaacata tgtattttct gtttatattt ttccttttac 297420 tcaggagtta ataggatatt tttaaaattt cttggtgaaa gcgcctttat cttattgtta 297480 gtaaagtcta tgtttttgca ttgtgatcag atagtgcagt ttttaatatt tcttgagtta 297540 ctaatttttc tttccaacct aatatataat cagttttttg tgactatgcc atgggcactt 297600 aagaacaaca cagatcttct attatctgtc aagtttaata tgtagccata aaatctacct 297660 tatttttatg ttgctatttt tgcccacttg atctgtcttt ttctgataat ggtgtattat 297720 agttttctat tatgggatca tctatgtctt gtctccttac atctcataca tctcatgcag 297780 ttttttattc ataaaggtgg ttattatgtt atttggtata taagtctcca taagggtcaa 297840 atcttcatgt gtattatatc ttttagcata aaaaaagtgt ccttctttgc cttgattaac 297900 atggtgggac ttgaatacat tgtgtgatat aagaattact acgcttgcat gcgattggca 297960 tgaaaaaaaa aaagattact cctatctctt tttgttttca tgtgcctgat atactttcgc 298020 ccatcccttt attttcagtc ttttagaatc catttgtttt agattcatct ctcatagaaa 298080 acatattatg ttttattttg tgagcccact gaaaatattt ttcttctagt aggtgtgtgg 298140 agtccactca cgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtagctatg actgatattt 298200 attgtgtttg tattttcttt atatttgcta cgctcttttg tcacggtgta gtctttgctt 298260 gcctatttat tcatacttag gagagttttt gtttttgttg gagtgtttac ttttgtacct 298320 ctcttaattc tgttagttct gtgttttcct agttaatctt ttacttctga tttatcagtt 298380 tgggggatgt tcttcagcac tcccctattc tcatgcaaag tgctttcggt tttcctcttt 298440 tttttttttt cctcctcctg tgtttagttg tcttatttct actttgtcac aatattagtg 298500 acatttgtat gctagtcttc taccctggat agggaatata cacctgtcag atggaaggaa 298560 tatcatgttg tatgctgctg tcaaatagat cctaacatac tttaataatc ttttaaatga 298620 tataatccaa gttcatagtt aactcctgac tttttatttc tatcatattc agtagatata 298680 tcagcattga cagccatccc actgcaatat cacttcacat tttgcttaga ccaaagggtt 298740 ctgagaagct tctggagctg ttgtgaaagc cagtttcatt aaagtcaagt cagacatcca 298800 cctgtgctgt tttctgctat aagctgaatg caggggatac aatgttagga gcatcagtgt 298860 ggtatgagga atgtttactt attggtagta gacttgtctg gatcaaggat aagtacaagt 298920 atctgagatg ctgaggtgtg gctgaatgaa tggccatctg ttctattgca acaggataaa 298980 taacacattc ggagcaggcc taactggtga actcctcaat tatctcacaa tagcactatc 299040 acgtgtcttt catttttcac agcacagtgt attttcataa aatctttatt ggtagaccac 299100 aactttagca tttcccattc aagatacaac tactgtgtca cttggatagc ttggtagaga 299160 ggaaattggc tattttcaga gtaaagaatt caaggaggaa acagattata aatgaaatga 299220 caaaggtgat gagatcaagc aatgctgacg tttgtagcaa ggagtagagg gctgagatgc 299280 ctgtatgata agaaattata atggaaccaa tcttgtgctt tattttttat taatttggag 299340 cattctctga tctgatttat tttctatgtg atattttgct gcaggttaaa agctgaaaca 299400 acttcaagga aacttcaggg aaaagaggtg agcagccact ttggtacttt tgaaattctt 299460 tgttctgtgg gcaatgatgt cagaatgtca aagactgtga gttcattatt tcagaggctt 299520 aaaggagatt attcttttgg tagatatatt tccccatggg tgtccctacc ttgttcaagg 299580 attccttatt attgtttctt ctctttgttt aaatctcttt ttgagatgac ctaaacaact 299640 gtggagaatc attgatatat ttcctttttt cactgttcat gttgggtgaa aataatcttg 299700 tagtgaaatt cacatgttct aaatattgtt tttttacatc tttatctggc acattcataa 299760 catagatgtt tctatacata ttagtactgt aatcatacca tatattattc tgttacccca 299820 cttactcctt aaacttttag ttaattaaag agtttttata aagtccccca atagattttt 299880 tttttttgag acatagtctc actctgttgc ccaggctgga gtgcagtggc gtgattttgg 299940 ctcactgcaa cctccccatc ctgggttcaa gcaattctcc tgcctcagcc tgccaagtag 300000 ctgggattac aggtgcctgc caccacgccc gactaatttt tgtattttca gtagtgacag 300060 ggtttcacca tcttggccag gctggtcttg aactcctgac ctcgtgatcc acccgccttg 300120 gcctctcaga gtgctaggat tacaggcttg agccactgca cccggccaga ttttaatcta 300180 attttattag aacaattcag tcatatgttt tttcatgcta tgtatatgag agttccatta 300240 ttcagatact aaacaaatgt ctactgtaca tttactgttc tcactgatga tgcattagat 300300 aaccatgcac aaaataagcc tggctgtgga aacgcttatt tgttgggagg gtgcttgttt 300360 ggatcgatga tgagaataat tgtctgagga tgctgaggga ctcattccag atgtcaatct 300420 gaggtccaga tgtgcggccc tccaatagga caaataagac tctcagagcc tggctctatt 300480 tggggatccc tcagtgacaa catagtaccc ctgtgagcgt gccttttcta tctcttcgaa 300540 gagggcagtg gcatcctgtc ttatgagtca gtgtgcactt tagtgtgcct agtgacccaa 300600 gacttgcttt aattgtagat agatacttac atataggaaa tatttcttaa gtaacaaatg 300660 aaaaacttta gaagattgaa ttaagggtca agcaactgtg atatgtctga aaatctcatt 300720 agtgttgtgc tgaaagaagg aaatatggca tgcctctatt aaataatgac agtggaacca 300780 agtttattgc tttgttattt ttactgtgga gtattttcta agattatttt tgcttttttt 300840 ttctttcatg ttttgctgag atagaaggcc tggaatctga tcctccactt cagagaacag 300900 gggtgagtag ctaagccatt atcttttgaa attcatatgt catgtgctct ttgctaggtc 300960 tttaggtcgt tttgtacatc ttttcagaag cttattggag gacattttca tgatatgtcc 301020 ttttcctcat tgagaccctc accatgtcac ctacactatt gaatccttat catttctctt 301080 ttaattttaa ctctcttttg cttttatgga aaaatgtaga atttaagaga atttttggca 301140 atttcatatt ggatcaaaat gtattgtagt gaaatccagg tgtgccaaaa tattaacaga 301200 ttttccccat ctgtttaatt attggggttt cagaatagag actccatggt tcataatatc 301260 tttgtggtca tactacatta tatttctgct tctaatttaa ttattaaata ttgacttgaa 301320 ttagtctttt cctcattgtt gcaacaaggt aagttatata ggaaattttc ttctcttgat 301380 ggcatgtctg agataatcat agatataaga cacctggctg gtttctagaa tgcatgtaat 301440 ttttatttct tgatctgtgt gttgagtact tgctgtgatt gcatcatgca aatacattga 301500 gctttacaat tttagtgtat gcacttttct acatgtatat tattcttcga tagaaagtaa 301560 aaaaaactta tcgaactagt caaaatattg gttaatacat aaaaaaagtc tcaagtagat 301620 tgtgtattac atggtgcttg ttgattgatg ccctcataat agatcaagtg ggttctctct 301680 ttagcacagg gctttttagc aaatcatgtc atgagtagtt actcaagtat ttttatttta 301740 acacatttat attttttcta tgtatattct taaattctct tatacttttt tctctgttat 301800 aaaaacatgc tgaacaatct caagtcttaa ggattgcagt attgtcccca catattcatg 301860 tattttggta ctcaattctt tatactttct ttgacagatc acttgaactg gcacatgtct 301920 cttgttttgc agagagggaa ttaatgtgat accttcatgc ttttctattc tatgtgctac 301980 ataattgaat atacaagcaa atatagttgt taagatttag tgtgattatt tctacaccac 302040 atgcaaagaa gtttctcata gatcttaata gaggcccaca tgcattgtac agtttagaat 302100 ttggggaaat attgatgaag ttgggtaaag tataaagcca aaagtcagaa cagtgaactc 302160 cttgcttaag gatttccttg gagattactt agtcaataca caactgataa atttaagtgc 302220 ttttcacctt ttgagttctc gacatactaa agctaaaatg tgtttcaact tttaatcctg 302280 cttccctgat tttccctttt ttagtctgag atcaaagagt ttcagccata aattactgcc 302340 aagagtaatc acttcatttt aagaaagctt aacaatatag aagaatataa aattatttat 302400 gacagatgta tttttaacct tttccccatg ctttccagag gaaatatgtt taatcatctg 302460 ccctatatta gggaaaaact ttctatgcta atacaagtat ctatcaatcc atttatcttt 302520 ctatataaga tgtattgatc ataaccaatt aactttactg taaatgagct ttagatttga 302580 cattttggta gtaatatatg ttgtacaatc tcctgaggtc ctataggtct tgaggtctct 302640 atgtcaaaaa ctatagatgt gccagtgtcc tcagtgaatg tgaaggacac cacattttcc 302700 ttagccattt cttgttttca gaataatggt tatcaacatt ttgctactgc aagataccat 302760 acatttataa tcggaatatg ccagttttta tgcactcatg cctctgtttc tgtagagcat 302820 tcccagaatg agtaatgctt gaaaattagg tccatgtgat ttctttaatg agttatagtc 302880 aaatcatgaa atattcaggt taccattatt tcagtaatgt attagaatgt caaggtaaag 302940 ttatctacat tgtatatata cacacaacat agatataatt tatacaacat ctatatttat 303000 acaacagata tatatttatg tatatattta tacaacataa aatatatttt attatttaaa 303060 cataaaatat attttattat ttaatataga ttcttaagtg ataaatatgt ttaatattat 303120 taaaataggt taaaataggt tatagttagt acagtgaaaa ttggcagccc ttttacaaaa 303180 catatgccat aactatagca tttatcactg acagtcatac caggatagtc ttttatttcc 303240 aatcacttaa atattcctaa ttgcaaaaga aatttgaaga ctaaaattca gaagttttga 303300 aagagccatt gcctgggtaa actatacagg tttcagtttt atttataata attatgaggc 303360 caggcgcagt ggctcacacc tgtaatccca acactttggg aggccgaggc gggtggatca 303420 cgaggtcagg agatcgagac catcctggct aacacggtga aaccccatct ctactaaaaa 303480 tacaaaaaat tagccgggcg tggtggcggg cgcctgtagt cccagctact cgggaggctg 303540 aggcaggaga atggcgtgaa cctggtaggc ggagcttgca gtgagccgag atcgcgccac 303600 tgccctccag cctgggagac agtgcgagac tccgtctcaa aaaaaaaaat tatgtatata 303660 tttataaatt aatacttaat aaattaataa cttgtgatag gcaatgcaaa gatgacagta 303720 aaaggacaaa attgattaga ttgataaagt cctgttaaca tgaagaaatt gaccaggata 303780 ccatccacac tataaagtta gagaaattta tcaggacaat tccctaaaat actcttctca 303840 attttaacat tgtaacagga atttttaaaa ttttggtatt atgtgtgttt ccttccagat 303900 aatttgaaca gattcatatt tggtattttt aaaagccata tctttgtcct tagtgctggc 303960 aatgtattct tgagaatgaa caaataagag atacgtaaaa gcataagaga aggtatcagg 304020 ttgaagtagt caatcagtta tacagaacac aaagaatttt atcttgtata atgtttatat 304080 agctttatag aagtgtgctg aaagggctat aaaacatgga cattattatc tcattgaaag 304140 gtccaatacg tactgaaata catgctttta ttttgaacca accaccctat aaacgttgta 304200 tggcttattt agatgagagc ccaggttgtg tgtgtctgtg tgtgtgtgtg tgtgtgtgtg 304260 tgtgtgtgtg tgtgtgtgtg tacctgacag ggaagcaaga acatcgagtt gccaatgcac 304320 tctgtctatg gttagaatca tgctgaaaac atggctcccc cagttctgga atgagcccac 304380 agatcaagca ttccccaaag acatagcagg ctcaaatccc tgtgtacaca atattttatg 304440 attatcttat gtcagtactt tcaaagtata cagtttgtgt gaagacaaat ccaatgtcat 304500 ttttcttggc tagcctatat gtgtggtaaa tccattattt acttacttgc ttcctgaaaa 304560 ttacaattag attaacaaac tgcagcaaag tgggcatgat gagatagaga ttgaagtgta 304620 agcttatgtt aatgatgccc ttggtttgga taaacacatc taagagaaaa atggaaaaac 304680 acacatggca gggaagcctt gatagagcca aaatatagga ttgtatgtag taatgcaatc 304740 catagatgag catttggcag taatattatt tttcagatat ggataaaaat tgcttaggag 304800 agtaaagaga gacaaagttg aaagcaggtt tatagtaggt gttgttttag tgttgatccc 304860 tttttgctcc aataatcaaa gtgataaata ttgaaaattg attcatgcag cattacttac 304920 tccattctaa tttttatata tgtcaaaagt gccatctccc aaactgtgct atccccttca 304980 ggagaagaga ctctgctgaa gtttataagg ttgacatatt gccagcttca ataatgtaaa 305040 gatgaagtgt atactgaatt cttaatgcaa ataacaactc tattggaaag taacccagtt 305100 atagaagtgc taatttgtca ggagctgcct taccaagatc atgatgagta cagttatctc 305160 aggattctga aagattgttt tccgatttca actagtctag ctgaatgttc cttgatagaa 305220 agagaggact tttagaattg gttcaatatg atgacctcct gaattatctc acatagcccg 305280 tttgtacatg cctttctttt ctctcagaaa atggcactat cataatagct ttcttacaca 305340 gacttcacct tagggtttta cattaaggga ggggtctggt gtttcattta ttttgaagta 305400 tttgttgttg attgtgtaca gtgcttgagt aaaaaattga atatagaaac atctagaata 305460 tttttttaaa ggatcagtgt ttataaagtg aattattagt gtcaataatg ttgggaaagt 305520 tttaagagaa tataggaaac ttgaacatta cacaactaca atgggaccaa attgtggggt 305580 ctcattatag ttaatattta tgtatttttt tccaattgat ttgtgtgctt tttttctgca 305640 tgtttttggc agatagaatg gctataacaa gtaacagcat gtcaggtaat aaaaataagc 305700 agagccctat tcctttaaaa atcttcactg atgggagggc cataaaataa gtcttaatac 305760 atttaaagaa ttaaattcat gtaaaccatg ttaatttaat tccacaatga tattgaatta 305820 gaaataagag gaatatctct tgaacatctc ctaaatgttt ggaaatttaa attagcattt 305880 ctgacctatt tattggttaa aaaagataca aagaaaggaa aattgaaaag tcttttgaac 305940 tgaataaaaa taaaaatata gaatctaaaa ctttatggga tactgacaaa acaggatata 306000 gggaataatt tatagcactg aaatgcctat attagaaaag aaaaaaggtt ttaaatcagt 306060 aaatttgtat tttaccttaa gaaacttaga aaagaacaaa ttaacccaga cttaagtaaa 306120 ataaaggcac taataaagat aagagcagaa atcaatgaaa tataaaacaa caaaacacag 306180 agaaaaattg agaaaattta aaaatagcct agtgagaaga tattgataaa cttgtaacca 306240 gaccaattta agaaaaaaag tcaaaacaca aataccaata tttgaaaatg taggagggca 306300 aatcattaca gattctatga atactaaaat gataataagg aaaaattatt taaaaggggc 306360 atgtcagcca ggcatggtgg cttacccctg taatcccagc actttggcag gccgaggtgg 306420 gaggattgct agagctcagg cattcgagac cagcctgggc aacatgttga aaccttgtct 306480 acacaaaaag tacaaaaatt agctgggtgt ggtgttgcac acttgtagtc ccagtcactt 306540 gggaggctga ggcgagagga tcacttgagc ccaggaggtt gaggctgcag tgagccatgt 306600 ttgtaccact gccctccagc ctgggtgaca aagtaagacc ctatgtaaaa aaaaaaaaat 306660 gtatgccaac atttttcaat aacttaaatg aaatggaaaa attccttgaa agacacgaac 306720 tacaaaaact cagtgaacaa gtaaataacc tgaatagccc tgtatcaagt aaattgaatt 306780 tgtagttaaa agccttccaa cagagaaaac ttcaggtacc tatagcttca tatgaaatga 306840 aaaaaaaaat accaatcctc tacaagattc cagaacattt aaaagaaggg aatatttccc 306900 aacttattcc atttggacag caatacccag gtaagaaaaa gagacacaga aatttaaaaa 306960 gaagaatata cattattcct taggaacata aatgcaaaga aatctaatca aaattttggc 307020 aaatgaaatg tagaaatact ttatgaccaa gtgagagtta cccaaagaat ttaaggttgg 307080 ttttatatgt aaagatcaac caatatagga aaatcacttc tggaaagtca gagtaagaaa 307140 ctccaaaaat ctactcctcc ataaaaccaa taacagcctt gatagaaata gttgaaatta 307200 attttccaaa actttggaaa ttaaccaaag gcttacaaaa ttccagagaa cattaattca 307260 agaaaaatgg ctgaatcagt aagaacagcc agctttgtgg cattttaata tgaccccttc 307320 ccatgctttt ctccctagtg ctgagatagt cttaaaaatt agcaggatag caaccactgg 307380 agaagaaagg tttggaaatt tcccaaaaag ttccatcccc atagaattat cactatttga 307440 cctctaaagc ccaatctata ggatttatat tcatttggac tgactcagag ctcactcagt 307500 aaggaaatct caatttcaag gtattggtca aaaagaatcc atggcaattg ttgactatca 307560 caactgcctg aagtcttggt aacagttggg ataaacaaga agctgatcaa aaactgaaaa 307620 ctaaaatctt gggaatgaga tatctacagg atgcttcaaa aagctttgat acattcctgt 307680 ttatctagaa agctacatgc aggctgggtg cagtggctca cacctgtaat cccagcactt 307740 tgggaggccg aggcgtgcgg atcatgaggt caggagtttg aggccagcct gaccaacatg 307800 gtctctacta aaaacacaaa aattagccag gcgtggtggc gtgcatctgt aatcctagct 307860 actcaggagg ctgagacagg agaatcgctt gaacccggga ggcggaggtt gcagtgagcc 307920 aagattgtgc cactgcactc cagcctgggc gacagagcaa ggctctgtct caaaaaaaaa 307980 aaaaaaaaaa gccacatgca tgtaattgtt tacctctggc tttcctttta tgctctgggc 308040 aagctaagga agagttgtga actacctaag tgctgaatgg gaaccataac acacacacac 308100 acacacacac acacacacac agcaccttag taaagggtga gaggcatgtt agttagaagc 308160 attaaaggaa atctctttct agtcattatc tgtgcactaa cctaactgag cagagacttc 308220 agtatccaca tactacaggg catataaact ttacagaatt agtccaggaa aatcatatct 308280 aaaaaaaaaa aaaagcagta acaaaaataa actctgggaa aggggagaat atgatttaaa 308340 gagttgccac attatacata atatgtctag tgttcaacaa aaaattacga gacatgcaaa 308400 gaaatagaaa aatatggcac aaagaggata agatgaagtc agtgaaacta tcctcgagga 308460 agaccagatg ttggtcttac tagacacaga cattgaacca gctattaaaa atacgtacac 308520 agaactaaga aaaacatgtc aaaagggtta aagaaaggta taaaaatagt gtcttaccaa 308580 atatagacta ccaataaaga gatagaaatt ataagaaaag acaacatgaa aaaatataaa 308640 gcaaaaaaat tagacaattg aaacaagagg gcctctattc gcagatttga gcaggcagaa 308700 gaaagaatca gtgaacttga agatatgtca actgagatta tccagtctga gcaacaaagg 308760 tgggaaaaaa tgaagaaaac tgagcaacaa agaactgtag aacagcatct ctcataccaa 308820 tggatacata aactggagcc ctagaaggat gaaaaaagga gaaggaaaga aaacttccca 308880 aattttaaga aaaacattaa tttatatacc cgagatgacc aataaaatcc aattaagata 308940 atctcaaaga gaccaacacc tatacacatc atagtcagcg tgtcaaaaga caaacataag 309000 gagagaattc ttgaagatag taagaaaaaa attattcata acatacacac catcctcaat 309060 aagtctgaca attgacttct cactgtaaac catgcaggct aaaaaggcaa tgtacataac 309120 caaagtgatg aaataaaaac cttcaaccaa tcattctaga tccaacaaaa ctattgttca 309180 aaaagaagaa atgaagacat tcctaaacaa aatctcagag aaatgttctc tataagactt 309240 gtcctaatag aaatgctaaa ggaactcctt cggtctgaaa tagaaaggca ctggagagta 309300 aatcaaatcc acgagaagaa ataaagagaa ccagtataag taactacatg tgtaagttta 309360 aaacaaagta taaatttatt ttgtttgtaa catttgtctt ttcctatttg atttaaaata 309420 taatctcaat tataaacttg tgttgatggt attatataaa gatgtaattt tgggttatag 309480 caccaaaatg gcagaatagg aattttctgt aggtgtttcc cacataagta tcaattttga 309540 caaccatcca tgggcaagag taccttgtgg gagttcagga gttgacagta aaacttcagc 309600 acaccagagg agtaaagaaa tctaagaata gattcattgg aaagggtata aacagtttca 309660 ctttacctgc atcaccaacc cccaaaagtg gcacagctca gtaacaagag cccattattt 309720 cttccacaga ggaaaaggag agtataataa gtaagtgtcc agtttctcaa gacatacagg 309780 cccctgccca agagatccac tttattttca tctcacccag aatattgagg tgatcagcaa 309840 ggtggagtgg ttgggagagg gtaaaagcag gaaagagaga tggggactca aacagcagcc 309900 catacttgga actgccatag atcctaccag ttacttcatg gactccatca ggaacccacc 309960 tataagccac aggggatgca tccctcccat cttgccaaca aaaccccgaa tgctccaaat 310020 gcctcaccca ctctttggct ggctcccaag tgcgctcctg tgaaaagcga gtgagtatct 310080 ctgcagatgg cttgcaagca catgttgaca gctggctcca ctctgtagaa ctggaaaaaa 310140 gctcacatac atgagaattt caggacacta ccctaaaaaa aaaaatgaga cttcagcacc 310200 tggcctggct ttatgcaacc tagagaaggt gatatgattt ggctctgtgt ccccacgtaa 310260 atctcatgtc aaattgtaat ccccacgtgt tggacaaggg acttggtggg aggtgattga 310320 atcatgcggg tggacttccc tcttgctgtt cttgtgatag agttgttatg agatccagtt 310380 atttgaaagt atgtagcatg tcccccttca ctctcttgca ctcctgctcc accttggtaa 310440 gacttgcttg ctaccccttt gccttctgcc atgattgtaa gtttcctgag gcctcccagc 310500 tatgcttcct gtatggcctg cagaactgaa ctgtgagcca attaaacctc ttttcttcat 310560 aaattatcca gtcttaggta gttctttata gcagtgtgag aatggactaa tgcagaaggc 310620 atacaacctt tagaatttgc ccccttgagg gaacaagatg tgtgaagcag gttcatccat 310680 agaaaatgtc tgagagaacc tcaaaatccc taacctgact aactgatgaa agtgtttctc 310740 tcctaaggcc agtcagtaaa gaccagaggg ggtgactgtt tctttaaatg caaaggcagc 310800 agcacaataa ttcaagaaac atgaaaaatc aagaaaacat gacaccacca gaagaacaca 310860 atcattttcc aataaccaac tccccaaaaa tggagattta caaattggtt tataatgaat 310920 tcagaacaat tatgttaagg aagctcagca aactaaaagg aacaccaata gactactctg 310980 tgaagtcagg caaacaattc atgaacaaaa ctagaaattc aaaaaagaga aaaattatct 311040 taaaagaaaa cccagaagtt atggagctaa agaatacaat gcatgaaatg aaggagcgta 311100 tcaacagcaa agttgatcaa gcataagaaa aaaaaaatct gtgaaactga agactggcta 311160 tttgaaatta ttcatcagag gattaaaaaa aaaagaatga aaagaaataa agaaagccta 311220 caggatgtat aaaacaccat caagagaact aatataagga ttattggagt cataaaggag 311280 aagagagaaa agggtagaaa acttatttaa gaaataatgg ctgaaaactc tccaaatcta 311340 ggaaaagata tgagcatcca ggtatatgaa gctcaaagat ccccgtacag gatacattcc 311400 aaaaagactt caccaaaaca catgataatc aaactgtcaa aagcaaaatc aagacgatga 311460 ataaaccacc aatcactaag agggagacag gattcttatg ttgtcattat tatttacata 311520 taatttcagt aaatgttatt ggaaaattta taatgtttta aaaaaagaaa tttgaaagca 311580 ccgaaagaaa agagactcat cacatacagg gaaccctttt aaggcattca agagatttct 311640 cagtagaaac cttacaaaat aggagagagt gggatgaact atacaagtgc tgcaaggaaa 311700 aaaatgccaa ccaacgcttt acctggcaaa tctgttcctc agaaatgaag gagagagaag 311760 aactttccta gacaaacaaa agctgaggca gttcatcacc actagacctg ccttacaaga 311820 catactaagg ggagttcttc aagctgaaat gatatggcaa tagttagtaa tatgaaatga 311880 taaacctcac tggtaaagga aagtacatag tcaaatttag aacactttga tactataatg 311940 atggtgtata aataatttta ctgtgctatg aaggttaaaa gacaaaagta ttaaaaaaaa 312000 cccatagctg caatagcttg tcaatgcata ctacagtata aaaagatgta aattagaaca 312060 ttaaaaacat agcatgcaag ggtagggaag taaaagtgta gttttcatat gtaatcaaat 312120 ttaatttgtt atcagcttaa aataaattgt tatacctatg ttttatgtaa gtgtcatggt 312180 aactataaag gaaaaacctc tagtagatac acaaaagaaa aagagaaagg aatcaaaaca 312240 taacactaca gaaaattatc aaattacaaa ggaagacagc aagggaggaa caaagtaaaa 312300 agagcaagaa aaaatttaac ataatgaaaa cagtaagtcc ttacgtgtca ataattactt 312360 taaatgtaaa tggattaaat tatccaaaca aaaaaacaga ctggacaaat ggattttaga 312420 aacaacaaca acaacaaaca ccgcacacac acacacacac acacaaacca cccagcccca 312480 actatgtgct gcctacaaga gatttacttc cactttaagg acacatacag gctgaaatta 312540 aaagaacaga aaaagatatt gcatgcagat agaaaccaga agagaggaga ggcatctata 312600 cttacagcat acagaaaaga ttttaagtta aaaactatat caaaaggcta agaaggtcaa 312660 aatggtgaag cagttaattg ttcaagaaga cataaaaatt gtaaatattt atacacccaa 312720 tattgaagca cctaaatata taaggcaaat attaatacat ataaaaggag aaatatacag 312780 caatacagta atagtagtga acttcagtgc ctccctttca aaaatggata atccagacat 312840 aaaatcaata aggaaacatt taacttaaac ttcactttag accaaatgga tctaacagac 312900 attatactga acatttcatc caacagtggt agaattcaca ttcttctcaa gcacacatgg 312960 aacattctcc aggatagatt atatgttagc tcacaaaata atattacaaa atttaataaa 313020 gctgaaatat caattatttt gcaccacaat agtataacac tagaaatcaa taacaagatg 313080 gaaactggaa atttacaaat atatagcatt aacatattcc tgaacaacca atgggtcaaa 313140 gaaaaaaatc aaaataattt tgtgacagca aagtagaaac acaacatacc aaaacataca 313200 ggacacagca aaagcagttc tatgaggtaa gcttatattg ataaacacat ttaaaaaaag 313260 attttaaata aacaacatta cacctcaagg aactacaagg aagaaaaaaa aacaagcccc 313320 atgttatcaa agggaaggaa ctaacaaaga tcagacagaa ataaatgaaa catagactag 313380 aaaaacaata gagactatta ataaaactta gagttagttt tttaaaaaat aaaatcaaca 313440 aacctttagc tagactaaaa aaagagaaga ctcaaataaa ataaaaaatg aaagaggaga 313500 cattacaact gataccacag acatacaaat taagagaaaa ctatatgcca acatattagt 313560 taacttgcaa tgggtaaatc cctagaaaca tacaacctac aaaaactgaa tcatgaagaa 313620 atggaagatc tgaacagatc aataatgaat aagggaattg aatcaatatt caaaaatctc 313680 acaaaaagaa aagctcagga tcagatggct tcactggtga agactgccaa ccatttaaaa 313740 aaattaatac cactctttat taagctcttc caaaaaaatt gaagaggaga aaacactttc 313800 aaattcatta taagaggcca gttttacctt gatatcaaag atttaaaaag aacactttga 313860 gaaaggaaaa ttacaggcca aaacccttga taaatataga tgcaaaaatg ctcagcaaaa 313920 tactagcaaa cctaattcag caacacatta taatggcata catcatgacc aagtgagatt 313980 catgcctcgg atgcaggata gttcaatata atcaaatcaa caaatgttac actactttaa 314040 cagaatgaag gataaaaatc atatgatcat ctcgatggtt gaactagttt acagtcccac 314100 caacagtgta aaaatgttcc tatttctcca catcctctgc agcacctgtt gtttcctaac 314160 tttttacaga tcaccattct aactggtgtg agatggtatc ttattgtggt tttgatttgc 314220 atttctctga tggccagtga tggtgagcat ttttcaagtg tctgttggct gcataaatgt 314280 cttcttttga gacgtgtctg ttcatatcct tcacctactt tttgatgggg ttgtttgttt 314340 ttttcttgta aatttgtttg agttctttgt agattctgga tattagccct ttgtcagatg 314400 agtagattgc aaaaattttc tcccattctg taggttgtct gttcactctg atggtagttt 314460 cttttgctgt gcagaagctc tttagtttaa ttagacccca tttgtcaatt ttgtcttttg 314520 ttgccattgc ttttggtgtt ttagacatga agacagtgtg gtgattcctc aaggatctag 314580 aactagaaat accatttgac ccagccatcc tgttactggg tatataccca gaggattata 314640 aatcacgctg ctataagcca taaaaaatga tgagttcatg tcctttgtag ggacatggat 314700 gaagctggaa accatcattc tcagcaaact atcacaagga caaaaaacca aacaccgcat 314760 gttctcactc ataggtggga attgaacaat gagaacacat ggacccagga aggggaacat 314820 cacacactgg ggatggttgt ggggtggggg gaggggagag ggatagcatt aggagatata 314880 cctaatgcta aatgacgagt taatgggtgc agcacaccaa cacggcacat gtgcacatat 314940 gtaacaaacc tgcacgttgt gcacatgtac cctaaaactt aaagtataat taaaaaaaat 315000 aatgctgcta taaagacacg tgcacacgta tgttcattgc ggcactattc acaatagcaa 315060 agacttggaa ccaacccaaa tgtccatcaa tgatagactg gattaagaaa atgtggcaca 315120 tatacaccat ggaatactat gcagccataa aaaagatgag ttcatgtcct ttgtagggac 315180 atggatgaag ctggaaacca tcattctcag caaactatca caaggacaaa aaaccaaaca 315240 ctgcatgttc tcactcatag gtgggaattg aacaatgaga acacttggac acaggaaggg 315300 gaacatcaca cactggggcc tgtcgtgggg tcagggtagg gggagggata gcattaggag 315360 atatacctaa tgtaaatgac gagttaatgg gtgcagcaca ccaacacagc acatgtgtgc 315420 acatgtaccc tagaacttaa agtataataa aaaataaatc atatcatcat ctcagtagat 315480 ttagaaaagc atttaacaat attcaacatc ctttcagaac taaaaactct caataaatca 315540 ggtatagaaa gaatgtgcct caacactata aaagccacat atgacaaacc tggaggtaat 315600 atactcaatg gtgaaaagta aaaagctttg actctaagat cagaaccaaa acaaggatgt 315660 ccattctcac cacttatatt taacatagta gttgaaattc tagctagagc aattaggcaa 315720 gaaaaaaggc acccaagttg gaaagaatga agttaaattg tctctgtaga tgacatgatc 315780 ttatatatag aaaacactaa agactccacc aaaatgctgt tttaattaga gcttaaaaaa 315840 ataattcact aaagttgcag gatacaaaat cagtatacaa aaatcagttg catttctaaa 315900 caccaaaaac aagttatcca aaaaattaag aaaacaatcc tatttgtgat atcatcaaaa 315960 aataaaatac taaagaatac caaagaaact gaaaataaat ggaaataaat ggaaagatag 316020 cccatgttca tggattagat gaattaatac tgttaaaatg ttcatactac ccaaagcaac 316080 ctacagatta agtgcaattc ctactaaaat tccaatgaca tttttcacag aaatagaaaa 316140 cacactccta aagtttgcat ggaaccgcaa aagactcaaa tagatgaagc aattttgagc 316200 aagaacagta aagctggaga catcacacta cctaacttca aaattttatt aatcaaaaca 316260 gcatgacata aaaacagaca gaaaagacca atggaacaga atagagagcc cagaaataaa 316320 ctcacgttta tagagtcaac taatattcaa cgaaggtgcc aagagtacac aatggggaaa 316380 gtatagtctc tacaataaac agcactggga agacaatatc caaatgcaaa agaatgaaat 316440 tacaccctta tcttatacca tacacacaaa tcaaatcaaa attgataaag acttaaatat 316500 aagacctgaa accatacaat ctttaggcaa aaactcattg acattggtct tggcaatgat 316560 ttttttgata tgacaccaga agcacaggca acaaaagcaa acctaaacaa gtgggaccct 316620 aacaaactaa aaagtttctg cacagcaaag gaaacaatca atcatcagaa ttaaaaggca 316680 atttatgaaa tgggagaaaa tgtttgcaaa ccacatatct gataaagggt taatatccaa 316740 aaatatataa ggaatgcata aaattcaata gaaataaaca aacaaataat ccaattttaa 316800 aatgggtgaa gaacctgaat agacattttt tcaaagaaga cttacagata ggcaacaggc 316860 atatgaaaaa atgcttgaca tcactaataa tcagggaaat gcaaatcaaa gctccagtga 316920 aataccacct ccaactatta ggatggctat tatcaaaaac tcaaaagaaa acaagctggg 316980 ggaatgtaga gaaaagggaa aagaagatcc ttatacactg ttggtgtgaa tttaaactgg 317040 aatagccctt atggaaaaca gcatggaggt tcctcaaaaa attaaaaata gaactactat 317100 atgatccagc aatttcacta ttgagtatat atccaaatga attaaaatca ctgtcttgaa 317160 gaggtatttg cacactcata tttatttcag cattattcac aatagccaag acatggaatc 317220 aacctaagtg ttcatcagta gatgattaga taaagagaac gtggtatata gacacagtgg 317280 aatctattta gtgttcaaaa agaaggaaat ccaactttta aaatccttta aaaagttaaa 317340 ctcataaaaa cagagaggag aatggcggtt tccaggaact ggagggtggg agaatgggga 317400 gatgttggtc aaaaggtaca aactttcagt tataaaatga ataagttcta gagatctagt 317460 gtacaacagc attactatag ttaataataa tattttttat acttgaaatt tgctaagagt 317520 aaatatcaat attctcaata cacacaaaac agaactatct gaaggcactg atatgttaat 317580 tatcttcatt atagtaatca tttcacaatg tataatgaat atcaaaacaa tagtgtacat 317640 cttaaatata tacagttttg atttgttaat catacatcaa tgaagctaga aaaaatgttg 317700 taatttttaa aacaatagta atataaatta ggggtgaagg aattgaccta tgttggagaa 317760 aagtttttgt aaactattta aattaattgg tatccattca agctagatta tttttaattg 317820 ttaatttaat tgtaatacta aggcaaccac taaaaaagcc tttaaaaaaa tatagcactt 317880 gaggctgggc atggtggccc tcaattatat atataatata tataaaatat atattatata 317940 tatagtagat gaacaacaat gggatttaaa tggtacacta gaaaatatct gtttaacaaa 318000 aagaaagcaa tagtggagaa atataagaac aaaaccatgt aagatttata gaaaatgaat 318060 agcaaattgg ttgacctaaa ccctatctta taattatatt aaagataaat gaaataaata 318120 ctacatcaaa aggcagagat tatcagaata gagaagaaaa atccaaacca taattcaacc 318180 ttatgttatc tgtatttaga atatttagag tcaagacaca aatagataga gttccatttg 318240 ggcgtgaaaa tatttaccat gcaaaatgta attaaaatag agctagagca gcaatactaa 318300 tatctgacaa aatatacttt aacaaaaatt gttgctaaag acaaaaaaga acattttata 318360 ataagacaca acaattataa acatatacac caaacaatag agcccaaaat atacaaagca 318420 aaaactgcta gaattgaaga aagatagaaa aatcaatgat tacagttgga ggtgtcaata 318480 ccaaactttc agtaatacac agaacaacaa gtcaaaagca aaaaggaaat aaaaaactac 318540 acattatcat acaacacctt aatacgatat ccaacaatag cagaatacac attattctga 318600 agtgcacatg gaatattctt caggatgaca catattaggc tgtaaaacat atcttaataa 318660 tttaaaagaa ttgaaataat acagcacata ttctctgact gcaaaatatt aaaccaatta 318720 cagaagaaaa tgtgggaaat tcacaatgat atggagattt aaaaatactt caaagtaacc 318780 aatgaatcaa agaacaaatc acaagagaaa ttagaaaata ttttagatga ataaaactga 318840 agaaacaaca taccaaaatt ttgtggttgt agctaaagca gtgcttcaag ggaaatgtat 318900 aacagtatat ccctaaattt taaaaaaatc tcaatccaat aacctaattt ttcaccttaa 318960 gaaatgagag tgaaagagca gacttaaccc aaagtaaaca gaaggaagaa ataataaaga 319020 ttagcatgga gataagtagt gaaaataaaa acaatagaga aaattaataa acttgaaagt 319080 tggttcttct gatatatcag taaaattgac gtattattag tttgaccgag aaagaacaaa 319140 agagagaaga ttcaagttac tagacataaa tgaaagtata gatatcacct tacagaaatt 319200 aaaagaattc taacagaata ttgtgaaaaa gtgaatgtca aaaaattaaa ttatatgaga 319260 tacacaaatc cctctaaagg cacaaactac cacagctggt gtaaaaacat gaatacacca 319320 tttacagtta aaaagactga atagataaaa attttaagaa gaaattgagt aagtaattta 319380 attttcaaac tataatccca agaccagatg ttttcattgg tgaattctac caaactttaa 319440 aaggattaat atctattttt catacactct ttccagaaaa tagaaaagga gggaacactc 319500 tataactcac tgtatgaggt ccgtattacc cttatatcaa gaccaaacat cataagaaaa 319560 gaagactaaa gacttatggt ttctgctctg atatgtttgg aagtcatcac tactattgtc 319620 acaaggaaaa atctgaacaa actaaagtca acgatttctt aaactaacca tagaattgag 319680 gtaacgggcg aaaactggag atgtaggcaa atacaaaaaa aatcacagtt tatcaggagc 319740 agaaactgct gaaaccagca actcgtatga acatgttaag tggtaattga caaatttctg 319800 gagattgaat gtggactgga ttgagagtta ggaactccta agtgcccagt ttttgatgac 319860 cccacacact tttgtaaact agacttccaa gagccccagc aagtttctta cagtgaagac 319920 tgcagaaaaa tcccctgatg cttcagatag gaggaaggga aaagcaacta ttttgaaata 319980 agcccagggg acaagtagtt atttctaaac actctcagag cattttcttt cacacggcag 320040 ggggctccct gcaagggaag ctactttgcc tgagccttgt ctgatgtagg agaaaaggaa 320100 ttggatggct caagctccat ctagcctttc tgatttatat aagggaagca aaaaataggt 320160 taagaaactc ttctgaaagt cacaactcag atttatttta tatttattta tttatttata 320220 ttttttgaga cggagtctcg ctctgttgcc caggctggag tgcagtggcg cgatctcggc 320280 tcactgcaag ctccacctcc cgggttcacg ccattcttct gcctcagcct cctgagtagc 320340 tgggactaca ggcgcccagc taattttttg tatttttagt agagacgggg tttcaccacg 320400 ttagccagga tggtctcgat ctcctgacct cgtgatccac ctgcctctgc ctcccaaagt 320460 gctgggatta caggcgtgag ccaccgcacc tggcctcaca actcagattt aaccataaga 320520 ttatagaaca cttctcctcc caaaacagag atatagatca atggaacaga acagagccct 320580 cagaaataac gccgcatatc tacaactatc tgatctttga caaacccgag aaaaacaagc 320640 aatggggaaa ggattcccta tttaataaat ggtgctggga aaactggcta gccatatgta 320700 aaaagctgaa actggatccc ttccttacac cttacacaaa aattaattca agatggatta 320760 aagacttaaa cgttaggcct aaaaccataa aaaccctaga agaaaaccta ggcattacca 320820 ttcaggacat aggcatgggc aaggacttca tgtctaaaac accaaaagca atggcaacaa 320880 aagacaaaat tgacaaacgg gatctcatta aactaaagag cttctgcaca gcaaaagaaa 320940 ctaccatcag agtgaacagg caacctacaa aattttcaca acctactcat ctgacaaagg 321000 gctaatatcc agaatctaca atgaactcag acaaatttac aagaaaaaaa caaacaacct 321060 catcaaaaag tgggcaaagg atataagcag acacttctca aaagaagaca tttatgcagc 321120 caacagacac atgaaaaaat gctcatcatc actggccgtc agagaaatgc aaatcaaaac 321180 cacaatgaga taccatctca caccagttag aatggcgatc attaaaaagt caggaaacaa 321240 caggtgctgg agaggatgtg gagaaatagg aacactttta cactgttggt gggactgtaa 321300 actagttcaa ccattgtgga agtcagtgtg gcgattcctc agggatctag aactagaaat 321360 accatttgac ccagccatcc cattgctata tatatatata tatacccaaa ggactataaa 321420 tcatgctgct ataaagacat atgcacaggt atgtttattg cagcactatt cacaatagca 321480 aagacttgga accaacccaa atgtccaaca atgatagact ggattaagaa aatgtggcac 321540 atatacacca tggaatacta tgcagccata aaaaagatga gttcatgtct tttgtaggga 321600 catggatgaa attggaaatc atcattctca gtaaactatc gcaaggacaa aaaaccaaac 321660 actgcatgtt ctcactcata gatgggaatt gaacaatgag aacacatgga cacaggaagg 321720 ggaacatcac actctgggga ctgttgtggg gtcgggggag gggggaggga tagcattagg 321780 agatatacct aatggtaaat gacgagttaa tgggtgtagc acaccagcat ggcacatgta 321840 tacatatgta acaaacctgc acattgtgca catgtaccct aaaacttaaa gtataataat 321900 aataaaaaaa ggctacctaa aaaaaaaaaa aagaacactt ctcctcccaa caccatatca 321960 ccacatcaac caggactcca gtgtaatagc agtgaattct aactgaaaga ggtgaaagac 322020 actgattgta tttaagaaag atcttctaag gaaatccaaa aatagtaggg gagatcaaaa 322080 caaagatact agaggaaatt gaatatgtga cacctatagc tacaaaaaaa ttaaacataa 322140 catagcccta accatataaa cataaaacct cacacaaaga cctattatct gagattctgt 322200 tgcctgatac attgcgtttt atttcaataa aaaaattaga gggtatgtta aaaagcagga 322260 aaagttagtc taaagagaca aattgagcct cagaagtagg ctcagatatg gcagagattt 322320 ggcaattata cctagagttt aatataaatg attaatataa taagtgttct aacagaaaaa 322380 ggcaacatgc aagaacggat gggtaatgtg atcagcaaga aggaaactct aagaaagaag 322440 tcaaaaggaa atgctaggaa taaaaaccta caagaaataa agaatgcctg tgatgggttc 322500 ctcagtagac tggacaaggt caaagaatca gtggatttga aaatatgtca acaaaaactg 322560 ccccactgaa atacaaaaga aaaatagaat tttaaaaacg taacacaatc tccaaaacag 322620 tgggacaatt acaaaagatg taatgtgcct aatgcaaatg acagtaggag tataaaggga 322680 gaaaggaata gaaaatctga agtaataatg gcagagagtt ttccaaaatt aatgctaaac 322740 cacagataca gcaagcccag agaacaacaa ggaggaaatt tagtaaagcg tctgcaacca 322800 agtatgtcat attcagactg acaaaaccaa aggtgaagag aaaatattga aagaagacaa 322860 agaggaaaat aaatatcaag aaaatacata cgaaatacat catacataca taagaaatac 322920 atcagaccat acaagcaaga agagaatgga gtgaaatgtt taaaatgttg aaaaaaaaac 322980 tatcaatttg caattctgta tccagtgaga ttatctttca aaagtgaaga gggaaatggc 323040 agagaagtca tctccaagac ctatggtttc ccttcacaga aacactgaaa aatatgaaca 323100 aaagtggtca gaattaactt tctaagaatt ctataaaatg gtaaaatgtt tacaccagta 323160 aagcaaatgc tgaattgaga aggcaactta aaaaggtgaa gaaaacttcg tattattttt 323220 atgtgtcctt gccccacgtc cttccctacc ttagtcttga agatggcagc ccacatttct 323280 actgtggggc tctggtttct gtttcctggt tcaagaggga gaataacaga ccttactttt 323340 agtcattatt atttccttct ttctgatttc cttgggttta ttttgctctt ctttctactt 323400 tattgaaatg agaactaaga ttatgatttg agacattttt ctaatgtaag catttagtgc 323460 tataaatttc catctcaaca ctgctttagt cacatcccac aaatttttat atgttgtaat 323520 ttcactttca tttagttcta tttttaaatt ttttcttttt atacttcctc tgactcacag 323580 attacttaga attgtgttgt tcagttttca aggatattgt agattttcct gtttctctgt 323640 tgtctaatag ttctgttcca ttttgtacag atagctcacg ctgtatgatt tcaatttttt 323700 aaaaaattgt gctttgtttt atggcccaga tatggtctgt gctgtgaata ttccatgtta 323760 ttataaagta tgcctgttat attattatat atatataata tatataatta taaagcatgc 323820 ccgttttgta ttgttagcag agtattctag aaatgtcaat gagatcttgt tggttgatgg 323880 tgcttttcag ttctatatct ttgctaattt tttttttttt tgcttagtag ctatatgaga 323940 ttctgagaga ggaaattgaa gtctccaacc ataattgtgg atttgtctat ttctcctatc 324000 agttctatca gtttgtgcat cacatatttg aggctctgtt gtttggtgca tacacaagtg 324060 gaatcattgt gccctcttgg tggcttattt tatgattata tagtgcctat ctttgtggta 324120 tttttatttg ctcttaaatc tactttgtgt tatattcata tacccattct tttttaaaaa 324180 aaattgtttg cgtgatacat cttttccatt cttttaatct cagcctatct gtgccattga 324240 atttgaagtg agttttcata tagagaacat attattgaat catcatttta aaaattcctt 324300 ttgccaatct tttttatact gaggtaaaat tgacataaaa tttatcattt taaagtgtac 324360 aatacagtgg catttggtaa tacacatgtt atgcaacgtt aactctacct ggctcctaaa 324420 tgttttcatc atccccaaaa ggaaacttca tactcattaa gcagttaatt cccattcctt 324480 ctctcggcca ctggcatccg caaacctact tttctgtctc tatgaattta cctattatgg 324540 atattttgta taaattgaat tatacaataa gtgaccttta tgtttggctt cgttcgcttc 324600 gcatactatt tttcgatatt caaccatgtt gtagtatgta tcagttttat ttgaataact 324660 caattctttt tgttgtatag ctaaaagttg attcctaggt cataatgata attctatgtt 324720 tagtttattg aatagctgcc aaagtttttc cacagtggct ctgtcatttt aaaatcccac 324780 tagcaatgga tgagagttcc aatatctcca catccttacc aatattgtta ttttatattt 324840 ttataattat aattttccta gtgaatacgc aatggtatct cattgtgttt ttggtttgcc 324900 tttccctaat gactaatgat gttgagcatc ttacaatgta cttgttaact atttgtgttc 324960 tttagagaaa tgtctattca agtgccttgt ccattttaaa aatcgagttg tcttgttgac 325020 ttatgagttc tttaatacag taaacgctta tcagatatga tttataagta ttttaaccca 325080 ttctgaaggt caccttttca cttttgtggt agaccattat gcacaaaggt tttaattttg 325140 ataaatccaa tttatccgct tttgttgttg tttttgttgt tcgtgctttt gcaaaaccta 325200 gtgtcatgag gttttctcat tatctttgga gaattttata gtttgggtct atacatgtag 325260 attattgatc taatttccat taatttgtgt gtatgctacg aggtaggggt ccaaattcaa 325320 tttttgcatt gaattgaaaa ttcatatttt cagtttcaaa tttcaactgc atattcagtt 325380 gttgcagcac aatttgttga agagatcatt ctttaccaca gggaatgatc tgggaccctt 325440 gtcaaaaatc aattgatcat agatgtatgg gattatttca gactttagat cttgttccat 325500 gaatatgcct atttttatgc cagcactgca gtattttcat tactgtagct ttatcataaa 325560 ttttgaaatc aggaagtatg tatcctccaa gtgtgatttt catttgctag agtgttttga 325620 ctatttgggg tctttgcaat tccatatgaa tttcagaatt ggcttttcat ttaaaaaaat 325680 ggtagttgag attttcatag gaattatatt gaatctacag atcactttgg gtagtattgc 325740 catcttaaca atattgtatt ccaatccata aacacggatg tattgccatt catatctttt 325800 tttcttttct ttcggcaaca tttagtatat gacacttgta actccttggt taaatttata 325860 cctaagcatt ttatcctttc tgatgctgtt taaatggaat tattttatta atttctcttt 325920 tagatggctt gttgcaggtg tatagaaata gaactgatta ttgtgctttt attgaattat 325980 ctgaaacttt gctgcattta ttaactctag taggtttttt ttttctttaa agttgtctat 326040 atatcttgct ctgtgaatag ataattttac ttcttgatct ccaatatgga tgcctttctt 326100 tctttttctt acctaattgc tgtagctaga attttcagta taatgtatga tagaagttgt 326160 tcacaactat ccttgtcttc tttctgatcc taggggtata gctttcagtc tttcaccatt 326220 aagcacaatg ttagctgtgg ggttttctta gatgccattt aatatattaa ggaagtgctc 326280 tgctatttct aattggttga gtatttttat tataaaatgg tgttagattt tatgacttta 326340 tgtactgcat aattgagatt atcatgtggt cttttcattc gattaatgtg gtatatttta 326400 tgattttcat atgttgatcc acctttatat tcttggggca aatcccactg tgtacacggg 326460 ttttttaggg tctcctaatt ttcttcattc tttttctttt ctctccctga gactgaataa 326520 cgttaactga cctatcttca agtttactat tttttcttct gctgttcaaa tctgcttgaa 326580 cctatagagt gaatttttca ttttacttat tgaacttttc agctccaaaa tttctctttg 326640 gctactttgt ataatatcta tctctctata gatattctct atttggaaag acatttttct 326700 cctggttttc tttacttatt tgtatttttt aaagtcttta agcatatttg agacagttga 326760 tttaagtatt tgtgtactaa gtccattgcc taagcttttg catagagatt ttatattaat 326820 ttcttttttt tctgtgaaca ggtctttttt tttttttttt tttttttttt ttttttagaa 326880 aactggacat tttgagtagt ataaacgtgg ctattttaga aataattttc ctccctcctt 326940 aggttttgtt tccacttgtt gcatgttgct gttgtttgct cattagtgac ttttctaaag 327000 tattttgaaa agtctgtgtt cttgatcatg tgggtccatt gaattctgta ttctgttaat 327060 ttcatagtca gctagtgttc tgaaagttcc cttaagtgca tagagccaat aaaagaaaaa 327120 gaaaagaaac acagaaaaag aaaagaggaa aaaaggaggg aaagagattt aaaaaaataa 327180 tgtcggttgg gcatggtggc tcatgcctgt aatcccagca cttttgggag gccgaggcag 327240 gcaaatcact taaggttgac catcctggcc aacacggaga aaccttgtct ctactgaaaa 327300 tataaaatta gccgggcatg gtggcacatg cctgtaatcc cagctactcg ggaggctgag 327360 aggtaggaga atcacttgaa ctcgggaggt ggaggttgca gtgaactgag atcacaccac 327420 tgcactccag cctgggcaac aagaatgaaa ctccatctca aaaaaaaata ataataataa 327480 tgcctttgcc gatttgctct gtgtttgggc cctcattcaa tgcctagtca ggccatttac 327540 aactctctct taactttcac tacctgcttg tgtactgact gaaggccacc tataggtgaa 327600 agcttaacat catctcagat ctttttggac catgaatcct accctgggta tgcacatgat 327660 cttcttaatt tcccagtaga tgcaagagtt ttagtgtttt aaaagtcctt attccctcat 327720 ctatcttctt ttctgacctt tttcagtctg cttattgttc atctgaactg acatcctttg 327780 ccccaagcgg ctgtggcaaa aacttttacc tttaaatgct ttcaccacaa gccacttggg 327840 aagctgcccc agacctggga ctgctctgac cctgatgaaa caaagacaag accttgtaca 327900 gccaggcagc cataagacaa gtccataccc aaaccacagt tctttcagaa taaggtctat 327960 attggattct ctggccctag taaccagcat gagtctgggc ttgccatctt catggccact 328020 tgtcttagtt tgctagggct gccataacaa aatatgagag actgagtggc ttaaacaaga 328080 gaaatttatt ttttcacaat tctgaagacc agaagtccat tactctgaaa tctctctcct 328140 tggcttgcag atactgcctt cttgccgtgt cctcacacag ccttttctct gtgtacacat 328200 ccctggtgtt ttttaagcct gtccaaattt tctgttcttc tgaggacacc aatcagattg 328260 gattagcgac cacccatatg atcattttac cttaagtacc tcttcaaagg tatcagagta 328320 gtatatttgc tacagttgat gaacctgcat acaacatcat cacttgaggt ctgcagttta 328380 cattagagtt catcgttagt gttatatatt ctagggtttg ttttgttttg agacagaaca 328440 gagtcttgct gtgttaccca ggctggagcg cagtggtaca atctcattgc tacctctgct 328500 tcccagattc aagcaattct catacctcag cctcctaagt agctggaact acaggcgcac 328560 accaccatgc ccagctaatt ttcgtatttt tagtggagat ggggtttcac catgttggcc 328620 aggcaggtct tgaactcctt gcctcaagtg atctgcccgc ctcagcctcc cccagtgttg 328680 ggataacagg catgagtcac catgcctggc cttattctat gggttttgaa atgtataatg 328740 acatgtatcc atcgttgtag tattagatag aatagcttca ttaccctaaa agtcttcttt 328800 gcactgggtt gagttttaaa agctctttga ttattttatg acagttcctt attagatata 328860 tcttttgcaa gtatttttat cagtctgtgg ttatcttgtc ttttacagag cagtaatttt 328920 taattttaat aaaatccaat ttgtcaatta cttatctcat atgactctgg tgttacatct 328980 aaaatgttac caccatactc aaggtcacct aggttttctc taggaatttt atggttttgc 329040 attttacatt tggtgtatga cccatttgaa gttaattttt gtgaggttgt aaggtctgtg 329100 cctagattca tttttttttt ttttggcatg ttacttcagt attcataaga aacattgttc 329160 tgtaatcttc tttcttatag tatcttagtc ttgctttagt ttttgggcaa tgctggcctc 329220 actgaataaa ttcaaagtgt tccctcctct tcaattattt ggaaaagttt gagaaagact 329280 attgttaact gttttctaaa tttttggtgg aatttaccag tgaaccaact ggtcctaggc 329340 ttttctccag taggtggttt tgattatgct ttcaatctct ttacaagtta cacatctata 329400 cagactttta taattcagtc ttggtaggtt gtgcgtattt aggaatctga ccacttcatc 329460 taagttatcc aattagttgg catgcaatta ttcgtagttc tctgaataat catttttatt 329520 tccacaaaat tggtaatatc ccagtttcca ttttttattt cattgaatct tcttttttct 329580 tagctaatct agctaaatgt ttgccaattt tgttgatctt ttggaagaac caacttttga 329640 tttattaatt ttctctactc tttttctgtt ctttatatta tttatttcca cactaatctt 329700 tactattttc ttccttctgt tggcctttaa tttttttttt ttaattttta aggtgtaaat 329760 ttaggttgag aaatttttta aatgaaagca tttagagcta taaattttcc ttctggtgtt 329820 cctttcacta cctgccataa attttgatat gttgagtttt tgtttgtctt ggagtatttt 329880 ctaatttgtc ttctaatttc ttccttgacc tattggttat ttaaatgtat ttaatttttg 329940 catattgtgg atttcccagt tttccttctg ttattgattt ctagttttat tccattgtga 330000 tcacagaaga tattttgtat aatcgcagtc tattaacatt tattaagtct tgtggcctaa 330060 cagaggatct atgttggaga atgttccaag tgcaattgag aatactattc tggtgctatt 330120 aggtgaagta ttctctatat gtctgttaag tccaattcat ctatagtgtt gacgtttcct 330180 gttccttact gattttctga cttattattc tatccattat taaaagtgga gtggtaaagt 330240 ctctattatt gtagaactct ctgtttttca agtctatcaa tatctgtttc atatattttg 330300 gagctctgtt tgctgcatat gtgtttacaa ttgttatatc ttcttggcaa attgaccagt 330360 ttcatcaaca taaaatataa ttcttattgt cttctaacag tttatttttc tttttacata 330420 aagcctattt tatctgatct tagattccct cacactccac cccagcacgc ttttggttac 330480 atttacataa tatatctttt ccatcctttc attttcaacc tgtttgtgtc tttagatcta 330540 aagtgaatgt cttacagaca gcataagcta tgtcattaaa aaaatccatt ctgcttatct 330600 ctgccttttg actggggagt ttaatccatt tgcatttaaa gtaatcactg atcattaaat 330660 actttcagta ttttgttgtt ttatgtatgt cttataactc ttttgctctt catttccttc 330720 aatattgcct ttgtgtttag cttatctttt tgtgtcacac tttgatcccc ttctcatttc 330780 ttttttatat tttctttgtg gttaccagga ggacaatgta tcaactttta aagttattac 330840 aattttattt ttttaaatct ctcccattcg gggattttag gaaggttaaa taataatgta 330900 aatgagatac ctagaacaat ataagcattc aggaattatt aactcaattc caatccttcc 330960 tccacctcca cctctttctc tgtgagatta tagaaaagat gacaaaaagg atgttttctg 331020 agccctttaa ttgttgagaa tgatctttga gaaaaagaaa aaaaatgaaa gcactaggaa 331080 tgtacaacag cctggaagta taattaagtg taaattaaat agataaaagt tataagcaga 331140 ggaaagtata gtagaactca gtatttaaaa gagaatcaat gtgaaaatta tataaattta 331200 tgtaaaataa aactaccaga caaatctgat atccttagga tttttctttc tttcatgtga 331260 tttctaattg ctacatatga cactaaacca ttgatctgag ctgtaagaga aactggaaat 331320 tgttctgtta tcttttgtaa gatttctaga acattttgcc ctcagactta aatgccaacg 331380 tatttctcac ttattgttta ctgcttttgg atttacatat gatttgattc tttcttatct 331440 cttatcctta caatgtaatt caaactgatg ccaatttaag ttcaattgcg tacaaaaact 331500 ctactcctat gcagctccgc cccatctaat ttacattatt gatgtcgcaa attccatctt 331560 tgtacatagt ttacatatta acatggattt atacattttt atgtatttgg tttttaaatc 331620 ctgtagaaaa taaaaagtca acacaccaat attaaaataa tactggtttt tatatttgtc 331680 catgtgctta cctttatcag tgttctttac atctttatac gggtttgagt tactgtcttg 331740 tgtcctttag ttccaaccta aagaactccc tttagcattt ttatagggca ggtctagtgg 331800 taatgaactc tctgagtttt tatttaggga tgtcttaatt tctagctcct gtttgaagta 331860 aatttttctg gatatacaat tctctgttga ttgatttttg ttcattttcc cttcagctct 331920 tttaaataca ttatcccact ttcttctgcc ttccaaggtt tctattaaca aaattcagct 331980 tataatctta ttaaagatct catgtacatg agtggcttct ctcttgctgt tttcaagatt 332040 ctgtgacttt ggtttctgat agtttaaata taatgtgtct tattgtgggt ctctttggat 332100 ttatcctaga gtttcttggt cttcttacgt tggtatatcc atgtatttca agacatttga 332160 gtagttttca gccattattt cttcaaacaa tctctcctct ttggggactt ccattttacc 332220 tatattggtt cttttgatgg tgtggcacca gtcccctaga ctttgttcac ttttttccag 332280 tcttttattt ctgcttctca gactcaacag cttcaagtgt tctgtattca agtctgctga 332340 ctctttcttc ttccagctca aatctgctgt tggatccccc cttgtaaaat ttttaattcc 332400 attttagtgt ttttcaagtt aagtattttt attaggttcc tttttataat ttctttttgt 332460 tgatattctc attttattac acataatttg tctgatttcc attagttttt ttctttgttt 332520 tcctttagct ctttgaaaat atttaagaca ttttaaaagt ctttatccaa gttcaatttc 332580 tatggttctg tagagatatt ttctgccagt ttatgttctt cttttccatg ggccatgttt 332640 tcctgtttct ttgtatactt tctaattttt ggttgaaaac tgagcatttg aaaatagagc 332700 caactttccc agtttctgca gagagtcttt atgccacagt attcgttcac tgattaactg 332760 ggtatatcta agcttaggga gcagctgagt caaaagttta aggtcttctc aggtcttttc 332820 tgagtataca tgtttcctat gcctgtgtga aatgttctca atttccctat ataaacagct 332880 acttcttctt tttttttttt ttttgagatg gagtctcgct ctgtcaccca ggctggagtg 332940 cagtcatctc agctcactgc atcctccacc tcccaggttc aaacaattct cctatacagg 333000 tgtgtgccac cacgtctggc caatttttgt atttttagta gagacagggt ttcgccgtgt 333060 tggccaggct ggtctcaatc tcctgacctc aggaggatta caggcttgag ccacagtgtc 333120 cagcctaaac agctactttt gaatgcttta atttcctgaa tagtctcaac ccagtttttc 333180 cttgaggtct taggtggtcc attgtatgtc tccacccata gttgcttgcc ccaggcatct 333240 gtgggtctgt ggtaccactg cagctttcac cacctgtagc tgccaccttt ccctatctga 333300 gatccaggtt aggtgagaga gatcattcct tcacgcagtc ccatgacagg ttggaacatt 333360 tcaaataagg tctgttctgc tcctctggtt gaagggagaa aattgggaac cggtttccca 333420 ccttctacaa accaagatct catgttgcca cgggagtggc agggcaagtg caagtgaaaa 333480 tgccatacaa ttttctacca ttttgaacgc gggtttttct tcaatggtca tttgcttggt 333540 tgctgtaggc ctttcactgt tttccagagc tcccataaga ttactttagc cagttttttg 333600 ttctttcctg atgcttccct ggcagagtaa gggttggaac ttccaccatt ttgctgattc 333660 ataactctgt agtcagtttt aaatatattg atacttgagt ttgttttatg gcccagaata 333720 tggtcttggt aaatgtttca catatactca gaaagaatgt gtattctgat gttgttacat 333780 gggctgttct ataaatgtta cttaaggtgg ttaataatgt tgctcaagtc ttctatattc 333840 ttgctgattt tcttttattt atttatttta ttttttttat tatactttta agttctaggg 333900 tacatgtgca caacatgcag gtttgttata tatgtataca tgtgccatgt tggtgtgctg 333960 catccattaa ctcatcattt acattaggta tatctcctaa tgctgtccct ccctgctccc 334020 cccaccccat gacaggcccc agtgtgtgat gttccccttt cctgtgtcca agcgttctca 334080 ttgttcaatt cccacctatg agtgagaact tgcggtgttt gtttttttgt ccttgtgata 334140 gtttgctgag aatgatggtt tccagcttca tccatgtccc tacaaaggac gtgaactcat 334200 ccttttttat gactgcatag tattccatgg tgtatatgtg ctacattttc ttaatccagt 334260 ctatcattga tggacatttg ggttggttcc aagtctttgc tattgtgaac agtgctgcaa 334320 tgaacatacg tgtgcatgtg tctttatagc agcatgattt ataatccttt gagtatatac 334380 tcagtaatgg gatgggtggg tcaaatggta tttctagttc tagatcttga ggaatcacca 334440 cactgtcttc cacaatggtt gaactagttt acagtcccac caacagtgta aaagtgttcc 334500 tatttcttca catcctctcc agcacctgtt gtttcctgac tttttaatga tcgccattct 334560 aactggtgtg agatgggatc tcattgtggt tttgatctgc atttttctga tggccagtga 334620 tgatgagcat tttttcatgt gtctttggct gcataaatgt cttcttttga gaagtgtctg 334680 ttcatatcct ttgcccactt tttgatgggg ttgttttgtt cttgtatatt tgtttgagtt 334740 ctttgtagat tctggatatt agccctttgt cagatgagga gattgcaaaa attttctccc 334800 attctgtagg ttggctgttc actctgatgg tagtttcttt tgctgtgcag aagctcttta 334860 gtttaatgag accccatttg tcaattttgg cttttgttgc cattgctttt ggtgttttag 334920 acatgaagtc ctcgcccatg cctatgtcct gaatggtatt gcctaggttt tcttctaggg 334980 ttttttatgg ttttaggtct aacatttaag tctttaatcc atcttgaatt aatttttgta 335040 taaggtgtaa ggaagggatc cagtttcagc tttttacata tggctagcca gttttcccag 335100 caccatttat taaataggga atcctttccc catttcttgt ttttgtcagg tttgtcaaag 335160 atcagatggt tgtagatgtg tggtattatt tctgagggct ctgttctgtt ccattggttt 335220 atatctgttt tggtaccagt accatgctgt tttggttact gtagcctcgt agtatagttt 335280 gaagtcaggt agtatgatgc ctccagattt gtccttttgg cttaggattg tcttggcaat 335340 acaggctctt ttttggttcc atatgaattt taaagtagtt ttttccaatt ctgtgaagga 335400 agtcattggt aacttaatgg ggatggcatt gaatctataa attaccttgg gcagtatggc 335460 cattttcacg atactgattc ttcctatcca tgagcacgga atgttcttcc atttgtttgt 335520 gtcctcttct atttcgttga gcagtggttt gtatttctgc ttgaagaggt ccttcacgtc 335580 ccttgtaagt tggattccta ggtattttgt tctctttgac gcaactgtga atgggagttc 335640 actcatgatt tggctctctg ttagtctgtt actggtgtat aagaatgctt gtgatttttg 335700 cacattgatt ttgtatcctg agactttgct gaagttgctt atcagcttaa ggagattttg 335760 ggctgagacg atggggtttt ctaaatatac aatcatgtca tctgcaaaca gggacaattt 335820 gacttcctct tttcctaatt gaataccctt tatttctttc tcctgcctga ttgccctggc 335880 cagaacttcc aacactatgt tgaataggag cggtgagaga gggcattcct gtcttgtgcc 335940 agttttcaaa gggaatgctt ccagtttttg cccattcagt atgacattgg ctgtgggttt 336000 gtcataaata gctcttatta ttttgagata tgtcccatca atacctaatt tattgagagt 336060 ttttagcatg aagggctgct gaattttgtc gaaggccttt tctgcatcta ttgagataaa 336120 catatggttt ttgtctttgg ttctgtttat atgatggatt atgtttattg atttgtgtat 336180 gttgaaccag ccttgcaacc cagggatgaa gcccacttga tcatggtgga taagcttttt 336240 gatgtgctgc tggattcagt ttgccagtat tttactgagg atttttgcat caatgttcat 336300 cagggaaatt ggtctaaaat tctctttttt tgttgtgtct ctgccaggct ttggtatcag 336360 gatgatgctg gcctcataaa atgagttagg gaggattctc tctttttcct atttactgta 336420 catttattcc accagtgact aaaacaggtg tatcaataaa atctgttccc tcaggttttg 336480 cttcaggtat tttgagggtc tgttatcagg tgcataaaca agattgttat gtcctattct 336540 taaattaatc tccttataat tatgaagtta attttttttt tcttgagatg cagttttgct 336600 ctgtcgccca ggctggagtg cagtggcaca atctcggctc agtgcaacct ctgcctcctg 336660 ggttcaagca tttctttgcc tcagcctccc gagtagctgg ggttacaggt acctgccacc 336720 acgcccggct aatttttttg tatttttagt agagatgggg tttcaccatc ttggccaagc 336780 tggtcttgaa ctcctgaact cttgatccac ccaccttggc ctcccaaggt gctgggatta 336840 caggtgtgag ccactgcgcc tggacctggc ccgaagtaaa cttctttacc cttgctaatg 336900 atctttgctc tgaagcatgc tttgctggta ttaatatagt cattccttct ttctttgatt 336960 catgtttgca gggtatatct gtttccattc ttttactttt aacctattgt ctttatattt 337020 aaagtgcatt tcttgtaagt ataattggtt tcttaaaatc caattatctg ccttttaaat 337080 gtcattttta tatgatttgc ataaatatga ttattattac agctaaattg aaatctgtca 337140 tcttgctatt tggtttctat ttatcccatt tttttcccct ctttttttgc tttccttgag 337200 attgaacatt gtattagttt tctagggttg ctgtaagaaa gtgacataaa gtggatggct 337260 taaaacaaca gaaatttatt gtttcagttt ggaggctagt catctgaaac caaggtgtca 337320 tcagggccgt attctctctg aaacctgtag ggaagaattc tttcctgcct gttctagctt 337380 ctagcatttt ccagcaattc ttggcattcc tttgcttgta gatgtatccc tccaatctct 337440 gcctctatca taacatagcc atcttctccc tttatctgtc tattcttctc atcttataag 337500 aacattaatt actgaattgg ggcccagcat agattaggcc taatctcatc ttgaataggt 337560 tacatctgcc aaagattctt cttccaaata agatcacttt tacagctttt acaggtactg 337620 agagttagaa cctcaatata tcctttggtg gggaccgacc tcttacccat aaaaagtatt 337680 ttatatgatt ccattttatc tcctttttag gttattaact acaatttttt tttctttttt 337740 ttgagatgga gttttgctct tgtagcccag gctggagcgc gattttggct cactgaaacc 337800 tctgcctccc gggttcaagt gattgtcctg cctcagcctc ctgagtagct gggattacag 337860 gcatgtgcca ccgtgcctgg ccaatttttg tatttttagt agaaacaggg tttcaccatg 337920 ttggctaggg tgggtctcaa attcctgacc ttaggtgatc cacccacctc ggcctcccaa 337980 agtgctggga ttacaggcga gagccaccac gcctggcttt ataatttttt tttaattcag 338040 tggatgtttt agggtttata gtatacatct ttatcacagt ctagctccaa gtgatatatc 338100 cctttatgta tagtacatga cccttacagt agtgcatttc catttttcct ctctggcatt 338160 taggctattg cacacacata cactcaattc atccctttgt gtagatccgt atttccagct 338220 gctatctttt gcttctgtct gaaatatatg tatgatttct tttatgacta ttttgagaaa 338280 tttggttatg tgcatttgtc tatttttctt atgtactttt agctcatcaa tcttaagtct 338340 gtgagtttat agtttttaaa aacaaatttg aaattatttg gctattattt cctcaaatat 338400 ttttttctgc cgcccctgct ttccctttcc ttagggatct ctgatttcca cctatattac 338460 tctgattgaa gttgttccac gtctcttttg aaaatctctg aaaaatcttt tatcatttgg 338520 ataatctgta tttgtacatc ttcaagtaca ttaatatttt cttttgcaat gtttaatctg 338580 ctgttaatcc catgtagtgg attcttcatc tcaggtattg ctgttttaat ctctagaaat 338640 tccattgaag tcttacttga tgaaaaaggc agataaaaac aaatgttggc aaagatatgg 338700 agaaatcaga atctgcacac actgatgatg ggaatgtaaa atggtcaagg caatttggaa 338760 agcagtctgg cagtttctca aaaggctaaa cgtagttccc atatgacagc aatcattcat 338820 ctaggtatat actccagaga aataaaaaca tatccacacc agaacttgaa cattaatttt 338880 catagcaaca ttattcctag gggtttaaaa ttttttacat tatttttatt taaaatagag 338940 acagggtctc actacgttgc ataggctggt ctggaactcc tggaattaag cattcctcct 339000 gcctttgtcc tgttttctcc actggaaaag aataaaactt tgtacacttg gactaacaac 339060 tcccgattcc ctcctttacc aacatgcccc acagcctcta gtaacttact ctctactttc 339120 atgaattcaa cttttttaag attccacata taagtgagat catacaatat ttgtctttct 339180 gtgcctggct tatttctctt agcataatgt cctccagatt catacatgtt gtcttaaatg 339240 acaggattta ccttccttta aaggctgact agtacttcat tgtgtatatg tatcacattt 339300 tctttatcca cttatctgtt gatgggcact taaattgttt caatgtcttg gctactgtaa 339360 gtaatgcttc aataaacatg ggaatgaaga tatcccttca acatattgat ttctgttctt 339420 ttggataata ctcagaagtg agattactgg atcatatggt tgttctattt ttttcagaaa 339480 cctccatact gtttttcata gcggctgtac taatttacat tcccactaac aatgcatgag 339540 ttcacttttc tggacatcct ccccaacact tgttatcttt catctttttc ataaaagcca 339600 ttatataata ggtgtgaagt gacatctcac tgtggttttg atttgcatta ctctaataat 339660 tagtgtgagc attttttttt tttcatgtac cgaatgtctt ttgagaaagg tctcttcatt 339720 cctttgccca ttttaaaatc aggtggtttt cttgctcttg agttgtttga gttccttatg 339780 tattttagat atttacccat ttccagatat atcatttata ttttttccta ttctttgagt 339840 tccctcttca ctgtgttgtt tccattgctg tgcaggtctt ttattttgat gccaccccat 339900 ttgtctattt ttgccatgct tttgcagtca tatccaaaaa aatcattccc aagaccaatg 339960 ctgtggagat ttccccctat gttttcttca gtaggtgtac agttttaggt cttatatgtt 340020 aagttttaaa tctatttttt tatatggtgt aaataagggt ctaatttaat tcttttgcat 340080 gtggatatcc agttttccca acaccattta ttgaagaccc tgtcctttta tacttttcag 340140 tatgcagatc ttttacctcc ttaaatttac acctcagtat ttaatatttg ttgctattat 340200 gagattttca taatttcctt ttcagatagc tcattaatag tagatggaaa cactactgat 340260 ttctgtaaga tgattttgta ttacggaact ttactgagtt tgtgtatcag ttctaccagg 340320 ttttagtttt gttctggtgg agacattaca gttttttgta tatggttatg tcatcagtaa 340380 ttacagatga tttaacctat tcctttccta ttaggatgcc ttttttttct ttctcttgtc 340440 caactgctct ggttaggact tctagtacta tgtcaaaaag tgatgagggt cgtacatggc 340500 ctccatacct aatctgttga gagtttttac catgaaacca ggttgaattt tgtcaaatgc 340560 tttttctgca tccattgaga tgatcatatg atttgattta caccctccat tttgttatgt 340620 ggtatatcac actttttgat gtgcatatgt tgaaccaccc ttgcatccta aggataaatc 340680 ccacttcatc atggtgaatc attctttgta ttcgtgaatc cagtttgcta atatattgtt 340740 gaggattttt gcatccatgt tcatcaggga tattactttg taagtttctg tccttaaagt 340800 gtctttctct ggctttaata acagtgtaac actacccttg taaaatgaat ttagaagtat 340860 tccctctgct tcattgtttt ggaaaagttt gagaattttt attagttctt taaatgtctg 340920 gtaaaattca gtagtgaagc tgcctaatcc tgggctttcc tttggtggga tactttttat 340980 tactggctca atctcttttc ttgttattgg cttattcaga tttgtttctt catgattcac 341040 tctttgtagg ttgtatatgt ctaggaattt attcatttct ttaggtcatc caatttgatg 341100 gtgcataact tcatagtagt ttcttataat cctttgtatt ttggtgatat cagtagtaaa 341160 tgtctcctct ttcatttctg atcttatttg agtactcttt ttttctccta gtctaggtaa 341220 gaatttgttg attttatctt tcaaaaaaaa aaaaaaccaa ctcttagcaa ctcttagttt 341280 tgttcatttt tttccagtct ttatttcaac tgtgatcttt gttacttact tctttatgct 341340 aactttcggg cttagtctgt tcttttccta gttcctttag gtgaaaagtg agattgtgat 341400 ccttcttctt tattggcgta ggtttgtatc gctataaatt tccattagga ctgattttgc 341460 tgcatcacat aagttttgtt tccattttca tttgtctcaa ggtaattttt tatttacttt 341520 ttgacttctt ctgtgaacta ttagttgttt gggagcatat tgtttaattt ccacatattg 341580 ctgtattttc caccagaatt gattcttgtt cttgatttct agtttcacgc cattgtaatc 341640 agaaaaggga tttgatatga tttctgtcca cttaaactta agattagttt tgtggactaa 341700 catatatcct ggagaatgtt ccatgggcat ttgagaacaa aatgtatttt gctgcttctg 341760 gatggaatgt ttcatatatg cctgttaagt ccgtttggtc taaagtgtaa ttgaaatcca 341820 ttgtttcttt attgattttc tgtctaggtg atcaatctgc ccatggtgaa aagtagagta 341880 ttgaggtccc gtattatagt attgcagcct atctccctct tcacatcatt taaaaattgc 341940 tttatgtatt taggtgggtc aatgttgggt gcatatactt ttacaattgt tatgtcttct 342000 tggtgaatta atccctttat cattatataa caaacttctt tctttttata gtattgactt 342060 aaagtctatt ttgtctgata gaagtatagc tacccctgct ctcaatttcc atttatatag 342120 aatatctttt tccatccctt cactttcagt ctatgtgtat gtttagtaga aaagtgaatc 342180 tcttgccggg cgcagtggct cactcctgta atcccagcac tttgggaggc caaggcggcg 342240 ggatcaccag aggttgggag ttagagacca gcctgaccaa catggagaaa acctgtctct 342300 attaaaaata caaaattagc caggcgtggt tgtgggccct tgtaatccca gctactcgag 342360 aggctgaggc aggagaattg cttaaacccg ggaggtggag gttgcggtga gctgagatca 342420 tgccattgca ctccagcctt gacaatagca aaactccgtc tcaaaaaaag aaaaagaaaa 342480 agaaaaaaaa gtgagtctct tataggcagt atgtggttgt gacttaaaaa aaaaaaaaaa 342540 tccattctgt cattctatgt ctttttgttg gagaatctaa tccgtttaca ttcaaggtaa 342600 ctattggtaa gaaactgcta gtgtcatttt gtaatttgtt ttctgattgt tttgtaggtc 342660 ccttgtttct tttttcccta ttgctacctt cctttgtggt ttggtggttt tctgtggtgg 342720 tgtgctttga atcctttctt ttatagtata tgcgattacc attgtatttg ctgtaaggct 342780 aacttaaaac attttatcct taggctactt taagcgataa aaacttgcct ttagttgcat 342840 acaaaaactc tacgctttca caaccccccc gcctttcgtg attttgatgt caaagtttac 342900 acttttttaa atttgtatct cttattgtag ctacagttac aattacttct tgtagctaca 342960 acttattgta gctacagttg tttttaatag tttcatcttt taaacctcct aataggaata 343020 acattgcttt acctgccacc tttacaatac tagagaattc tgactatgaa ttacttatac 343080 catttagttt tttactttta tgtttctcat taactagcag tcttttattt aagcctaaag 343140 aactcccttt tagtaattcc agtagagcag gcctagtagt gacaaactcc cttaggcatt 343200 gtttatctgg aaaagtgttt atttctccct ttgccaagta aagtattctt aattaacagc 343260 tttgtttcct tcagcacttt gaatatacca tcccactctc tactggcctg taaggctttt 343320 gctgataaag ccactgaatc tgtattgggg ctaccttgaa tgtgatgttt cttatctttg 343380 ctgctttcag tattctttgt ctttgatttt tgataacttg gttgtgatgt gtcttggtga 343440 actctttagg ttgaatctga tcggtgacct cagcttcctg ttcctgaatt ttgtcatctt 343500 ttctcagatt tgggaatttt tcagctatta cttccttaaa tatgctttct aggccttttt 343560 ctttcttttc tccttaagga cctcctatta tgcaaaagtt agctagcttg atgtgtcctg 343620 taattcttat aggcattctt ttttgttttt gtttctcatt ggataatttc aaatgtctta 343680 cctttgagct cattgattct tctgcttgat caagtctgct gttgaagcgt tctacttaga 343740 ttttcagttc agttactgta ttctttatct ttagaatttc tattgttttt gtttatattt 343800 gttaaacttc tcattctgtt cagatgttgt tttccaaatt tcatttttct atccatattt 343860 tcttgtactt tgttgaactt aagaggatta gtctaaatta tttgtcattt cacaggtctc 343920 catttcttct gagtctgtta ctggagcttt catatccaat gtacaccaga aactttgcta 343980 attccacagt aaatgttaga aatgggtttt tattgataaa atcagtggct tgctaattag 344040 tatgttagaa gctggcttgc attggtgaag ttgagggtat tcgatatacg tatcccggct 344100 aaaatacttc taaagaacct ctccagcttt gcaagaatag agtataggaa tctgaggagg 344160 cctttaacat ggccctcaga aaggacacac agggcttgac ctctaaacat ataaacatat 344220 acagaaacga ggtcagaaca tgttttgact gatgccagta gtaacacagc agagcctatt 344280 gctggtcact gttaccaata ccttgtgtaa taaacctttc atttaaattg agaggttgta 344340 agccccgaaa aagcaaaggg cttacagtac ctcttgcctg aacactcctg tgtgtgcttt 344400 ctaagaaatg cttttaaaat aatgcctgtg gcacaaattg atttgacact ggctctcttt 344460 ataagctgct atcaaggttg tggggaatag ctaactctta cccactttcc ctgacaaata 344520 ggaacccgta gttacctacc aaaagtatgt aaaagctata tccgacccaa aggccagtta 344580 ggtcaaaaca ccttgaaagg agctcagttt aaggaaatca gtggtgtcac agtgccccac 344640 tagcgtgtaa aagttttcat agtttgacta tcggatgtgc ttagtttcac agctgagtct 344700 taccttgtga tacttttaga gcaaaagtca aatcaaagat gatttaaaaa aacatttcaa 344760 agattcataa agaataaatg cctcctcagg aagtcttctg gagttctgcc cacttccctt 344820 aggtggctct ttactgtgcc catctcatag cctgtctcct tccacttggt gtattgcaga 344880 gtaaagctca ctgtttacag gggtggtaga aagtgtggtc ctttcccaga ctcctttttc 344940 ccttcctctt ctcatttttc agaagatgtg tttgataata aacgaaacaa aatgactaac 345000 acattgagct gagctacata agcagatgtc agtttgacgt gaagagttta aaagatctat 345060 gcattatctg gggactcctc ccccagacct gaaggatcag gtgctgcctt ctatgccacc 345120 tgtgcagaca gcaaaagagg aaaaccatac ccacgttcag tatgaacaaa ggggacattt 345180 gaactctgtg tggacccctc attggaaggg tgtttcttct cctgctgcat ccacaaagag 345240 cactccttag ccttgccttt tgtcagttct ctctccaata aggcttgagc agagacaacc 345300 cagtgcagtt cagagagact gaagtctggt gttccaggtc tgagtcctag ctctagctct 345360 ctgtgtaact ttgggatgtc ccaaagtaac ttttcacaac ttgataggtg ttaacttgaa 345420 ttttggatac aggtgactct tagcccatcc cctctctgtg cttcagatat gtcatcactt 345480 gggccatatg acctctggac acctttccta ctttccacaa tttcagagca gcagagcaga 345540 ctggagctcc tgctgcctct gagcttcagt gaattatcac tcgttggagg gaagcttcaa 345600 gcattttgtt atctttcaag agcaaacaca gtgtctgtca gcaagaatat gtagcagatg 345660 ctagtgaaca gcagtgatta gggttgaatg ctggatttaa atatggagct taggctgtga 345720 aggaagcctg aagaacctag agccccatga agctgccctc tgtgagatct gacaccattt 345780 cccactgatg agccatgggt ctaatgggta gcactgattc cacatacagt atgtgagtgc 345840 aatacagtga aagcaaagag aataaaatga tggctaacat gatgttccaa actttaaaca 345900 ggagaaaaac acacaattcc attatgtata agaacccaca cagagatcag gagaataacc 345960 tcattggaga atgaatgacc tgtgtgggga atttagggta gagttgagat tgaaaaaatg 346020 ggccgaagtc aggtggccaa gggccttaat accttgtata caagatgtgt agtcaaggaa 346080 gaccatgcct tacttatgca tcaattccct tgggcctaca aagagctgcc tagcctggga 346140 ctgttgtaga gaaaagctac agtgttccaa tgacacaggg actcctccat gtatgtatga 346200 gtgcccagct ggctctgtaa taaatcttat ttttatttat taacttttct tgcgcattgg 346260 cttgatgcat cagttggaag tcagaggcca aacgaagtga acactgagcc aaaggaagtt 346320 ctcagccttt agggaggcag aattcacttt aaacacaata aacaaatgaa ctcacattat 346380 acaggagaga gtcagaagat cccagtggct ggtgtcatcg ggccatattt gcccgaagtg 346440 cctattcctt ataggaaccc actcccaggg ttgatgggct acatccttag gaggctttat 346500 gcctatgttc tcctgaccac tggctcctcc agggctggcc ttttttagtc tctctgtaga 346560 ggttcctgta gctggttgga tataggcttt cacagaaggg tcagtgcctt gggtctggtt 346620 acaggactgt taatcttgct ttgttaagag taatgttatt tccccatttc caaattctcc 346680 agggagatgg aatgtcaaag atagtatgac tgtagcacct aaatcctggg ttccagaagc 346740 agagaagaga atacactgaa gctgtagaaa ggcctattag tccatgtcag agattaactg 346800 gatgcgagga ccatttctgg gatggtgtat acagaactgg agaactggat agggagtcag 346860 aaacaaagag ctgaagatga tgcctttgaa gtttccaacg tggataacta ggtcaacaga 346920 atattactca agaaagtatt aacataggat tgagatgcag tcagtagtaa tggaattgaa 346980 atttcaaagt atatacctca tggatctcag ggggtgttga gctgatcacc tgggctaaca 347040 ctcctatgac cctggggaaa atcaaatgac ctggtactgt agccatggta ggggtgtcat 347100 caccttaatc caactgggac agtgctgttt gatattcatc tggaacttgg tgcagaccca 347160 cattttgctg ggtttcacca caaccaaggc ttttttgatt cttttctctt ttaacatcag 347220 tacatcactg caaagttaat cctcatataa taggagatga aactaattgc ttataaaaac 347280 aagattttta caacactaaa attgttcaag catatgggca tatttatagt tgcaggcagt 347340 gtttcagatg cagactgttc ttggctgcag tggttgttta caggcagcat ctgttctgat 347400 taaatatttg atgattatcc ccgaatgttt taaagcatag tactgggctc tgctgactgt 347460 acaacaaact ggcatttttg acctataggg cactgggcta ggagatacag ttctgaggga 347520 agtgaaagat agttaacaac tgcacaactg accctttatt agttgcaata aagcaatcca 347580 accacccaac ccactgtgat ggctttccta ctatttaagg ttggtggtgt caaagagaca 347640 ccctcctgta cagtgtgcag tgaatcaaca tcatttccac aaaacctcct tcctgcacaa 347700 aggaattatc atactttgtt acgaagtaaa attttcctgt atcagtcaca ggagttcacc 347760 agttaagata ctgttagttg aagacttctg gggtgactta atgaaatagc tcagccatct 347820 ggtttaaaaa ctggattctt ctatccctcc acacagctgt ccatgcacct gcatcatctc 347880 aaggctggtc tccctggtgg tagaaaggct gacagtaaaa actggagcca catgattcct 347940 tgcttaggca gtgtttcttc atactctcac atgagagcag gcatgttctt tccctaggct 348000 cacagtaaac actctgtcaa atctcacagg cccaaagtgc ttttggttat ccccattcca 348060 agccaatctg tggcatggaa gatagcatta ccctgactgc cttagactaa tatacctact 348120 ccacttctgg ggctgggaat aattttgagg tcaaccatcc aaactgcatg acagccattc 348180 catggaagag gtatggccta aatctttggg gcaacctgaa ttcatgaaaa ctctcttaga 348240 tttatgtaac tatttttaga attcacttct gtatcattta attttactaa taaaaatacc 348300 acctttaccc taaatgtcag ccaagcgtaa ggctccgttg ggacagaagg aactatcaaa 348360 gctttgtgtt tttatacatt agcagcattt gacaaagaaa taactctgaa ggaaggagaa 348420 taaccaggca gagtctagat gcatggaaaa gaagtctttg agaaggcttc gcaggctgaa 348480 ggaaagggca ggactacttc aggaatacaa cgtttaagta aaagaggttg gggtctgttg 348540 atcttgagga gagatgagga tggactggaa aataggagtg agatatagta ggagaggaaa 348600 ggatatggat gatgtatata ctgtatgggt aaccatcagt cgaccctaag aagataatag 348660 ttgttaaatg gttagctatt taatgaaaga aacctgaaca agtaataatc ttgagttgca 348720 aagtggctgg agtcacacaa cagactaaat ttctggtaga acaaatccag cagcttatgt 348780 gaaggttacc atgtctgaag ctggatagaa aaggtctaac ttccaaccaa agtcacagtt 348840 cttgagctcg gtacacagag acagactgct aacagctgat gtgtcctcag cgagagtgtc 348900 ctcatttata tcctcgttct cttctgcctc ctttttttgt tttaaacttt tgggaagtct 348960 catcattcaa tacagttcta atatatcaca ataacagagg cggcccaatt tctacaaatt 349020 gactaattct atccctgaaa agttcataca ataaaactat acaaagcatc attttcaacc 349080 atcctataga aaaatttccc tattaaattt taactctaaa tcctctatct ctgttaataa 349140 ccttactaaa aacttcccca tcactgcctg ccagggagat caaaagaaac caaatttaag 349200 aaacctccaa cacctgtacc tgactgaaaa gcaaacatac agacctttca gtcctgcccc 349260 tactattcag ctcctatcac agagacatgg tggatgtccc cttgggaagc ggatagctct 349320 taggtggaag ctaggcctgc aataagcagg ccaggaaaca tgtctcccag gccccatact 349380 cttggcagaa gcacttggcc accagacagc atgtcctgtc aacctacaga gttcttaaaa 349440 acaaacactg ggacccagaa tagtaccctg tggtcatagt gcccacagtt cactaagcac 349500 cctcacaggt ctttgacaga acactgactg ccaggtcacc tggtgggcag agaaatggaa 349560 gattcccagg cccaactagc atctcaggga agaaccacaa gcagagcaac tttcagagct 349620 ggtcggccag cgttggcacc cagggaagca agtgctattc catatttgga gagaacataa 349680 aactcaagga aacagagaag tcctactcaa taccgttctc aactgaaaac aagagaactt 349740 gcaaaaaaga aacccagttt tctggagtcc atggagaaat atgaagccaa tgctcggcta 349800 acagagcaga aagcctttta taaataatgc cagtcaaagc tccaaaggtc agagctgatg 349860 catgccggat tgttctgaca atttcttagg tttctaggca acaaggagct ggtcaaacag 349920 ctcacctcca aggacatact ttataatacc accctggtag acgagagcga ggcagcagtg 349980 aaggcaatag tcaagaacag gagagggagg taaagaacaa gatgctcttc agacagtctg 350040 gacaaagaca gtccctaccc agctctcagg agttgcctcc ttaagaaggt ggaggcccag 350100 gcagctccca gggtgaccct aaagacagac tccaaggaaa agggtgtgag ggcaatggtg 350160 aatataagga ggtccccttt cagtaggcag agcaagtcag ttcaggtctt atttttagag 350220 tctctgaaca gtgaagagaa gctttctgtg gacagcattc caccaccatg ggaggggaaa 350280 ggtgccatga gagacttctc cagtggggca tacaagcatt gtgcagtgat ccccaagatc 350340 cagccactgg caggaaatcg aaaggcaagc ttcttaaata catagtatat ggagacagaa 350400 gtgtggagca ctcccaaaat gaaaggccaa gacccaggaa caacctccac aacctggagt 350460 atatacaaat gaacccagcc ctgctgactc agatccacac catcctaaag caggggtttc 350520 tcatgaatga aagggctaag tatttggtgg agagaatgag aagtctccca ctgcccacac 350580 attttttctt cagagatttc ttttccaaga gccccttgaa taaaggaagg gagggagcac 350640 tgaatgcccc agaaatcaga atgcatggtg cgggaagacg acaggaaata gttctcaaag 350700 agatcagaaa ataaattgga agcaatttca ttaccacaaa gaacagacat tttttctaag 350760 gcacccctcc cctttccacc caattgtcat tcagcaacta ctgaatactt accaatgaaa 350820 aacgttaccc ctgacctcaa ggctgctcct gagctctggt agaaaatgct ttccttgtct 350880 ataaaacatg gcaagcaagg caggatttaa cagtaagggc acagtagcac tgcaagcctt 350940 caaatggaaa cctggagaca agcagtgaga acaggaagca aaagcagggc aggtgaagct 351000 aggaccaggg catctggaac tttccacaca ggttggatct ccatgccaga caacagtttt 351060 caaggaaaaa tatctaagag gaacatgact ttgggaaact ttttggcagt actgcttact 351120 gtatactaga gagtaaaaga atttggggaa cattcaccaa tttgcttctt caggggcttg 351180 ggtagggaac gtgaacagga acctggctct aatttctgaa cttttttatc agtaaaaaca 351240 atccaacaaa cgaaagctag tcagtgagag aactgggagg gtctgccctc cttccctgag 351300 tcaagccttc tggggggacc tcctgacatt taattaagca aagacaacgc ccactgaagg 351360 aagctgacct gaaagtgaca cgctactgtg aaatgagcat gaagtgggag cttgttacat 351420 atatgaaatg gccagcgatc ctgagcaaag cgcttcagag cttgagacct aagtcttctc 351480 atctatatac tgagggctgg acaagatgat ctgtcaagcc atttttatcc ctaatccacc 351540 aaaatccaat gctttagttt attgtcacaa aagcaggtat cgaatggcta tcctgcagtg 351600 cctccaatca acattcagac tttttccctg aggcaatata agataacagt taacatgttt 351660 ttatcaatta ggtggtcatg agataaatat atatgggaag tggtagtttt tcacttaaat 351720 gcatataata atggtacagc tctctttgaa tagtatttgt ttatttctta aatatttaag 351780 ttcctaaaga cggtaagaat aacccaagga agtgaaatca atgtcacaaa gcacatggct 351840 aaataactgc aggtttgcag tgccatgtgt gagatcagat gacagaaggg agaactacct 351900 ttaggcagag gcttctcatg tcccctggag tggccatgtg ctgttctaca tgactacttc 351960 cacttcggtt atgtagaagc tatttaaagc acacagatgt ttgtgatgag aaaaaagcca 352020 cccttaattg aataatggaa attataagca tgatttgagg gtgggggtgg aggtgggagt 352080 agagatgggt agaaaggagt gcaatggaaa caaaggagcc ttcataaaat tcaagtcact 352140 tcttaggata acgtgattga tttactcacc accttcttag gaacataaag caaacaagtg 352200 ggttttcctt ttactgcttt tctgaaatga gctacactca agaaagcagc acgggggttg 352260 tgctgtccct gcacagtggc aggagagtat gaggagcagg tgaatgccac aacagctcca 352320 tccaagatca tttttcacat gcaggaacca ttcttatact accctttact ggtaatttct 352380 gtagaaatct ggaagtctgg ttgacaccct cctgtacagt gtgcagtgaa tcaacatcat 352440 ttcccttgga ctttgcaatc acggtggcat tcatacattc attcaacaag tatgtatgta 352500 caggacagtg gagtaaagaa aacagatagt tcttactctc acgaggctta aaatttcagg 352560 agggaactag gcagtcatga agtaaacata aaaacacaga ttgtaatagg cactagagaa 352620 taatgaagac tttggggaac acaatttaaa ttggaaaaat atctcagttc cgttaacaca 352680 tgttgaaggg gaatagcatt gttttgctgg atttggggcc tggatgcaag catgttgggt 352740 atgcattgta gggtaatgca tttccttcca tttgggccca agtgtatatt taccacccag 352800 ttgtgatgag ctgggatcct cctgctcaat ctcagcttga agcacttgga ggttatctgc 352860 ctgctgtggg tgattatttt ggagcaaggt acttcatttg cctcaagaaa cagatttgat 352920 accactactg tgcccttttg gaacagagaa gtaggcaaga ccccagtgtg aggcagagtg 352980 atgggatctt tagggacata attgatgatg taactgatga tgattttgga gtttatacat 353040 ttccaaagtt tcaaaatatt ttcacttggt tgatttatct ttatggtgat gacactacgt 353100 agatatatgc ccttcttaaa agttacagta agaggctggg agcggtggct cacgcctata 353160 atcccagcac tttggaaggc cgaggtgggc agatcatgag gtcaggagat tgagaccatt 353220 ctggctaaca cggtgaaact ccgtctctac taaaaataca aaaaaattag ccgggcgtgg 353280 tggcgggcgc ctgtagtccc agctactcag gaagctgagg caggagaatg gcgtgaaccc 353340 gggaggcgga gcttgcagtg agctgagatt ccgccactgc actccagcca gggcaatgag 353400 cgagactccg tctcaaaaaa aaaaaaaaaa aaaaaaaaaa agttacagtg agagttgaca 353460 ttgagaaaag ggaggcccag ccagggttat gcaaagacac agtagggagg aggatgggaa 353520 gtttctgaga caccccagta actgcatggg tccacaaagc acatgtacag tctgctctat 353580 gcactgcagg tacagccacg aataagacaa agtctctgcc ctcatggagc ttggtgtctg 353640 tctactggag cagacaaaaa caaacctgct ttttctcatt tgcctctact gtgggttccg 353700 tgtataactc tcaaatgcta gcatttccat gcattccatc cttgtccttc tctcctctct 353760 gccttttcca ggagaatttt cctagccaca ggttcagcta tggtctatgt gctggagtca 353820 tacattttta tcttctgtgt acgtttttct ctagacccat atttttaatt gccttaggac 353880 agctctccct ggatatccct cagacacaac taaaacatca ttcaattgta ctattaataa 353940 ttttcccttc aaaatccact cctcttctct atagacctaa cagcaacact gtccgtccag 354000 ctctcaaaac ctgaaatgtg ggagttgtct ttgactctta tctttcccat gcatgagcac 354060 tgaatcaatc agagtcccta gcatgtcttg gactgtggcc tcccttctat cttcagatta 354120 tctgcctttt tagaattatg gcaataactt aactgcaaag accacatgtg cacttgtgct 354180 ctttcagttt gtaataaata taaaatgaaa agtgattatg tctttgctta acgtctgcaa 354240 aataaaagtc caaagtcctt ggtatggtct ataaggccct cattatctga cctgcctgcc 354300 ttcccaatct catcttaatc ccttacagcc tgacactcag acatactaga ctttccacct 354360 aactcactca catacaccta tcctgtatgt caagattcgg cttgaccttc atcacctacc 354420 tatctgcagt atttttggat ctgaattctc tgcccacatt gtactttcac atacttcttt 354480 tacccttagt ggtttgtact tatgcctggt ctaactagat tgtctccctg taacagactt 354540 cttgattcaa caaagcagct ctgaatcagc ctgaaaccta tggcacactg caaaatggca 354600 aacattcaat aggtatttgc ccagtaaatg ttaatgaaag gaaaaaaatt caaacttcag 354660 ttggaatagg attagagaca agttaaaaaa aagtttccca tagaaatctt cctcatcgta 354720 aatatcatca tcctaaatgt cccgagtctt tccatgggtc taatttacca aatcatgaag 354780 actctctttc tcactgtgta tgtgtagtgg gagaggcaga gacagaacgg tttttttttt 354840 tttttgcaag tctgctctct ggattcgttt ttctggggat gaaatctcag gctatgtagc 354900 ttttctggtc cctttttggt aatcaacaaa tcatcagttt ctctaggtat taaaaagcct 354960 acacttttga aacaccaaga ggccaaactc tctcttaatt gaaaacataa ttctgcctct 355020 tactgaggtc tttgggtggg aagcttaaag acagcagtgt tggggcaatt ggtttttctt 355080 ttcctccctc caccttcttt cccattcaag agctgttgct gccctttctg gaggggaggg 355140 aattagaaaa aaagatcctg ccttacccag tcactgttaa ttattacttt gagccagggt 355200 ggggaatgac tttctttcct ggaatacacc ctgctggaaa ccacagctga gattctctaa 355260 gctggcagct tccaacctct cctccctcaa cagcttcaac attatatggc actcagctgc 355320 agggtgcctg gctccaggcc ggcagtccat ttgtgcaggg tagttttcaa gatggctcat 355380 agcccatctc tttcagtgac cagcgtggcc tatgggaaac atacatcttg actccattat 355440 tggtaggagt actctttagt taactgccac aggccagttc agacacgtct taccctgaga 355500 gccttttcag agtcaggtac catccctgtg tcccccagca tctgaagatc acaggtgaag 355560 gtctccaagt agttcactta aaaaatacct cagtaggttt aagaacaggg aaagctccca 355620 attcattctg tcaggagtat gactctcatc cccaaactgg acagatatat aatatgaaaa 355680 ctacagacca atattcctta tgaatataga tgcaaacatt ctaaacaaaa tactagcaaa 355740 ccaaatccag cagcatagaa caaggtttat gtagcatgga caactgagat tatcccagga 355800 atgcaaagtt aattcaatat acaaaagtcc attaatacaa catattaata aaggacaaaa 355860 caacatgaaa atcttgatac agaagaagca tttaacaaaa cccacagccc ctcctttttt 355920 tttttttgat taaaaaacac tcagtaaact aggtttaata aaagaatttc ctcaacttga 355980 agcaaaccca cagctagcta acatcatact caatggtgaa agactgaatg ctttcccctt 356040 aaaatcagga acaagaaaaa gatgtctgct cttgtcactt ctatccaata ttgtactgga 356100 ggtgctagcc agcacactaa ggcaagaaaa tgaaataata ggaatctaga ctggaaagga 356160 agaagtaaaa gtatttctgt tcacagatgc atgatctcat atgcaaaaaa tactaagtga 356220 caaaaaaaga attttagaaa agctacaata tacaaaatca atatacaaaa attaatttta 356280 tttctaacac cagtgatgaa tacaaaaata aaaattagaa aataatcata taattaaagt 356340 ggcatcagta aaatacttag aaaaaaatta aagacgtcaa gacttgcaca ctgaaatctc 356400 taaaacatca ctgaaataaa gacctaagca aatgcaaaga catcccacag tcatggaaca 356460 gaaaacctaa caccattaaa atagcagtta tttctcaaat ttatctacca attcaactaa 356520 atccctatca agatcccagc tgttttgcag gaattgacac aatgatcata taaaaattca 356580 tatgcaatgc aagggaccca aaacagacaa aatgattttg gggaaaaaaa aaaaaaaaat 356640 ggaggacttg cacatcccaa atctaaactt actaccaagc tacagccatc aagacagtgc 356700 ggtgctggta taacgacaga catatagggc aatggagtaa gactgagaat ccagaaagtc 356760 ttatatttat ggtcaactgt tctttgacaa gggtaccagg accattcatg gggaaataat 356820 agtcttttca acaactggtg cttgggcaga tggatataca gataccaatg cacttatgca 356880 aaaaatggat gaaataggaa acttcactac attctactgc atgctcggtc attttcaatc 356940 atttaggtgg caacactgac aagataacag aaagatggag gtaataacat gtgaaaggca 357000 aaatggtttg tttttttttt taaaaatgac agtctctatc atgaatttac ttacactcca 357060 ggcaaaggtt attagaagaa aaaaagatgt aagaaaattc cttaactgaa atgtggaaag 357120 agtatcaaga ggagacccta agacactctg taagaatccc agtgactcct cactgttcaa 357180 ctaagaaatg taccccatta tgctgtgcta ccacggaagc attggaggca ctttgggggt 357240 tgatgaagtc ttcatggatg aggtacttta aatatctggt catgaagagt atttgagaaa 357300 tatgacaagt gaagatgctg ggtaggaatg cagcgaggaa agtgtgtaac acaaggccaa 357360 attggaaagg tcagtgaggg ggcaatctgt ggaggcactg aatgcagagg atattaaaat 357420 tagcaagata gtgttctagc acaatgaaaa ggattggaag agggagatga gagtcaggga 357480 gtgaaattag gcagctgcta agaatgtccg ggtgagtcag aggatcagga cctgtaaggg 357540 cagtataaag aaggaaggaa tgatgggaga ggtttagggg gaaagaagtg acaacctgtg 357600 acaattgagg aatgagagat tttgatgatt ggggtgaagg ttacatttct taaaaagaaa 357660 caaagaatgg tcggtcgata gagatgcaag atgaagaatt ttgtttttag gactactgac 357720 tatgaggtaa caaagaaatc ccagagacag aggtctgagc aaaagatatg ggattgggga 357780 agaatctttg ggagtgactg aggttgacta gagggaactg ggcaagaaca ggtaaggact 357840 ttaagcagaa ttggaggagt atccatctaa aatctgggta aactgggatg gaaaaacaag 357900 tagccagaga agcaacagcc caagctaggg tgttgtcaag gttatagatg ttactgattt 357960 tggcaatgag gagattataa ggatccttga agactgtact ttcggtgaaa ctaccatgca 358020 ttagtagcct ttcacagtga tatctacccc acacctgcat caaaatcttg cagtgcctat 358080 taataaatgc caacccacta acggggaggg gagaaaagac ttgggactct gtacttgtaa 358140 aaccctctac cctccccagg caattcttta cacactaaca ctgttgaggt aaaaggagac 358200 aagtgaggga gcaaatggaa ggtgtgtttt tggattatac agtggctcat ggaagggtgg 358260 gaggggtaca gatggccctt agacactggc ggaaagtcag agaaaaaaaa ttacagtaag 358320 caggtaaagg gatcaagact acacagggac tagtcttggg acgacatttc ttcctctgac 358380 agtttgtatg gaattcttga gaaaaattcc tcgaaggggc ctgaaatctc agaatggtca 358440 tgtttttaat gggaataggg agtgatgctg ccccattaca accatctgtt ctaacagaat 358500 gtctgtaccg aggagggatg agtaacatcg gcaagttctg ttcgaagcct ttttcaagtt 358560 tctttttgat atgtatctat ctatctatca tctccctata caagcaagca tccccaaaag 358620 tagttgtctc aggaaaccag ggttaggatg accagctcat ttgctggagc tgccaaggtc 358680 cagaaaagtt tggctgcagg ctgttttcat gttttatgta tgtttgaaat gttctataat 358740 aataaaaggt taaaaaagtt tacatttatt tggaaaacca gttactttag tttatggttc 358800 ctttttttcc ctccagagct tcctggagat tgaggtctaa ttcaaagaaa accaaaatat 358860 ataatagagt acctgggcaa aaaaagtact tttataacat aacatttggg gtagaggaag 358920 tatccactgt agtcaaaatg tctatgtttt gctcttcctt attgttcagg gacattccat 358980 taaatagtaa tgaaaaggca gcaaaagtaa gaggagtgac aacatgcccg gcataattaa 359040 gcaagctaga gcagctattc tgtgcaaccg acgatttttt ttctctaaaa ttttaagggt 359100 aggttcattc tgactctgtt aaaagtctac ttgatgtgaa caactctata tctgataacc 359160 tatttcaatt accactttaa aacttgtcat atggatacgt tattacaatt gtagaacttt 359220 aataaatacc ataataataa aacttgagaa ctgaagagca cacatttctt cacgaattta 359280 ttatataaaa cgccctcaga gtatttaatt tctcctcact ttaattacac attaagaagc 359340 acagtggatg agaagccttt aagatgacta cagttgcacg aaggtccctt tcatcaaggt 359400 agcgtatgta ccctaacagt gttctaaagg ctggcccaga aaaaccccat gttaccttat 359460 cacaatatgg aaagcattgt cttctttttc cactaaatta aattatggtg aaaagtgcca 359520 cagttttatt tagcattatg gtacataaca aacagttctg tctcaattat gaaaaaaatt 359580 aattaaaata atcctgaaag acatcctttt tctcccccca atgatttgaa agctgcattt 359640 ttcctgccaa tttcaaacaa acaaatcatc aggttgatct acagtaatca gttaaaacaa 359700 tcagtcaatc aatcaatcaa tcaccaaggc acaagctcag cacattagct atagcttgta 359760 gcaaaaggat atatcaatgt ctcaccttag ttaaaaatac ataatccttt tattttataa 359820 tgcaataaaa gaaattaaca acatcacata cacagaagac taggaaaggg gaaactactt 359880 acttctggaa atcagtaatg taaacctact tgtacttttc catagtacat gaaagtaacg 359940 tttaacatgt tttgaattaa ttaattaaat ttaatctgtg gggctataca atgtaattct 360000 taggagtaat agtttcattc atttccaggt cagcttactg tatgattaag taacacaagg 360060 cacagtagcc atctttttca ttatgttgca acactgatca cgtgcctcga taaaatggct 360120 gattcaacaa gatgatggca acacgaaggg gagactttgg attgtctatt taaaatctag 360180 gtaataagta agtaattaat aaaaactcta tcttaagtgc actttcacat gctttttgtt 360240 tataataaac aaacaacaaa cttcctaact ttgttgcaat aggcttgact accatttcat 360300 ttggccaaat gcactttccc cagtaaactt aaaacaacaa cgagaacaac aagaacaaaa 360360 atccctgtcc tttcatatac taagaaagag gattggctac tgaaacagtt cattgcaaga 360420 cacatgaaga cgacatactg tggcatgagt tgtttttgtt tttaatttgt tgtgctgtta 360480 ctaaagttct gagggctgca gttaaaacat tccaatttct cccttccttc catctttctt 360540 tattgattga ttctcaagat tttgcacaga aaactctttg ggggctagaa cagcagtaat 360600 tgcatcacac tgttttcaag acttcaagtt tcaaaagcaa atcattaaaa aaaatacagt 360660 tcctgatttg agttagatac agggacaaaa aagtagcaca tacttgaagg ttacgtggtc 360720 tacaaatggt ggcaatattt tccttgggag agtagttctg ttggtatata ttttttaaat 360780 actcaaaagg ctcaacctca agcagtaata aacacaagca aaagtgattt aacccttaaa 360840 ataaatattc agaaaaacct ctctgtacat acaagtgaaa gaatatgtaa cactttcacg 360900 caaaaaaata attataataa taataaagga tttgttcata tatgtagctg aaatctgctg 360960 ttccagccca catgtcccca ataaagaagg gaggcacaga cataggtgac tactgtggtt 361020 gactatctta cagccttttt gtactgggac actatcacca ccaaaaattt atccctcgtt 361080 atatttttaa aattttttaa attttttctt tttttttcct tccttttttt tgttttattt 361140 tgttttgttt tgttttacag catgccaaat cctttggcat acgtgatggc cttcaacaat 361200 ctctctttaa gtttttcttt gcttgagtat tccggaagta aaagcacatt aaagcaagta 361260 tgagatgtag gtaacctaaa tagagaaaag gggaaaaaaa caggaaaact gtaagtcatg 361320 ggaaatacac ttagaattaa atgctcctat ttttagattg tatatagttg agacggtctg 361380 caatgcaaac tatacattaa tgcaaatcat aaactttttg ttgtgtaact accaagttgc 361440 ctttatccta taaattactc aaagctagtg acgatgataa gatactgtat ccattgagtt 361500 tttactacat aacagatacc attttaggta ctgaattctt acagttcatt taactaaatc 361560 tttccacaac aaaaccacag agaggacatc agtaaatgca ctttagaggt taggtcactg 361620 agaagtcaag taacttcctc taaggtggag aaaatactca aacctgtttt acaagactgc 361680 aaagtgtgtg ctcttaaatg cttattagaa acactgctgg caatatgact aagaaaatga 361740 tttgataaca ggattctagc acaatcaaat gataatcttc cgagcctcaa tgtaaccatt 361800 ctaaatagat gatcatgtta tatggctttc aattaacaag ctgggaatca aaaaagtaaa 361860 tgaatcacac taatttgatt ccaaaccaat gtgagcccca taataatttt taactagggc 361920 aatttcttaa aagtttcctc acacaatgac agcaaagtat tttctcaatt gtctaatatg 361980 atttggggat ttgtatataa aatcacgaat gtgctcagaa actataaaga cagttcatat 362040 gtatgtgacg aggaatgcaa ggttttcggt aggtatacag tcacaagtta ataattacct 362100 acctttctgt gtctgggcca tttttggcta taatcatctt taattttcct agtcctccca 362160 caggtgctct gtctgtgccc gttgtaaact gcaagaagag tcttttctgt tcatctgtaa 362220 atgaatgaac gatttcccag aactccctaa tgagaaaaaa tacaatactg gtttcagttt 362280 ggcattcatt atgactggta ctaacataag cttatgattt gcattaaaac tatattaaga 362340 gacaacttgg aagttaatta tcaggatagt atcacttctg gtgatttaaa aatttccaag 362400 caaatttatc ctgaacagct ctgaatacgt aaaaatttag attagattac aatatagtaa 362460 aatattagta ctacaatagt aaaaaattga gaaaacccaa gtgtgtagta acaggaagtg 362520 actatttaaa ctatggtata atcacattat gcagtcagta atgagcaaaa gacaaaatcc 362580 tatgaattga aaaagactga aatgaatatt tggaaaaatt aactccaggt gcctttgggt 362640 atatatttta tttatccttt ctcctttatt ctcctggtct actcatcctt taactcaact 362700 ttgggaggaa aaagtgatac agattaagga caaaagaaaa aaagaccccc tgccccaacc 362760 aactggcccc aaatgcaaac aactacatac ctaatagcag taatacaaaa gttcaatttt 362820 tatatgaact agaatacttt aaacaagtaa tatgtgctgt gtatggagga ggagaattat 362880 tctgacattt ctgccacctg cagttatttt aagagaatga tttatcctgt ggcattccta 362940 aaatctatgt aataaaagct atgttttaat gacacttatg ttagtttgag ttctaaaaaa 363000 cgaaatacaa gctcataaag tgcaatcttg aagtttattt gaataatcag gcatctataa 363060 aacatatata cactagttca tagctaaata aatttttttt tttttgagac agagtcttgc 363120 tctgtcgctc aggctggagt gcagtggcgc gatctcggct cattgcaagc tccgcctcct 363180 gggttcgcgc cattgtcctg cctcagcctc ccaagtggct gggactatag gtgcctgcca 363240 ccacgcctgg ctaattttct gtacgtttaa gtagaggcag gatttcacca tgttagccag 363300 gatgggtctc gatctcctga cctcgtgatc cgcccacctt ggcctcccaa agtgctggga 363360 ttgcaggcat gagccaccgc gcctggccta tagctaaata atgttaagat taaaaaatta 363420 aaaaaaaaat taaaagtatt tttagttgct tatataatat aaaatgcatt ttaatagtta 363480 tttagaaagt tctttccaga gccaggtgtg gtggctcatg cctgtaatcc cagcactttg 363540 ggaggctgag gccagtggat cacctgaggt caggggttca agatcagcct gaccaacgtg 363600 gtgaaaccct gtctctacta aaatacaaaa attagccggg cgtggtggca gatgcctgta 363660 atctcagcta cttgggaggc caaggcagaa gaattgcttg aacatgggag gcggaggctg 363720 caatgagctg agatcacacc attgcactct agcctgggaa acattttgag ccatctcaaa 363780 aaaaaaaaaa aatttcatct caaaaaaaaa aaaaaaaaaa attccagaat gttagcagag 363840 aacatcacac atcccaaacc agtaattaca attttctacc ttttgatatt ctaatatccc 363900 aacatactat ttttattacc aaaatgctgg catttttggt gctgcaacac catttatctg 363960 aaataactta aaagttttat tagaattctt ggctttctcc aatctcttgc cacttccctt 364020 ccctgcccct ttacaaatcc accagtcagc aagagaaaac aaaaaagaaa cacacaacaa 364080 cagaaaactg gacatgaaac ttgcaggagc atctctcagg taaggaggag aggaatcgga 364140 ccccagttca tgatactcct tttggggagg ctgacaagag aaaacaagtc tgctgtagca 364200 cagaaccctc caacatagca gaaaagctgc cctgcagtgg gtggtaataa agcctcctca 364260 cactgcagga gggctctgaa gcttaactga accagctaca cctaaggagg tagaccaaag 364320 agcaccaccg aagaacagag acagaccctg caggaagtgg cagatcagca gtggtcacaa 364380 tgaccagtct ggctatatta ttacggagct gtttctttgg acttttaaac gaaaccttta 364440 aaaattttat acaatgaaaa cagggaacaa aatgcatctc tattcctata agtgttatgt 364500 gtgttacatt aacattttga attaaacaag aatgcatata tttagaaagc tgaagaaaac 364560 acgaagaagc ttccaggttt ccacataaaa gtggtggctg tatcgatcac atcctactca 364620 catctctaaa aatctacccg gatcaaaaag gggaaaataa aaaaaaaacc tatgacttag 364680 gtctagagta aaactaggag acagaacaat aaactccaaa taccaaagaa gtggggaaat 364740 gagcagggtc cagcaggagc tacatcgaag agtggcttgt gcggaatcat actgattagg 364800 gatcacccaa ggccagaccc caccccctcc accacctgcc cctcaacaga gcactactga 364860 gtgtaggtta gagcactggc aacagggtgg ttaaaggaag gactacagaa aagtacttgg 364920 gtccagcaat ggcaggctca ggaaggcacc atgcatgaaa ggaagggggg taccttcaaa 364980 agcagaagtg tcccttaagc ggctgtaaag gggtggaagc agctaatgaa aaagagtctt 365040 cattaagcta catggagctg aaaaatcaga aagtggtgat tctgccctta ctaaagcaac 365100 agaagaggga tcccttcaac caagacccct aaagccacac aattcctccc tgctccacca 365160 tgaggtctag taataacagg tccagaaaaa agtaacatct gttatagaaa cataaacaag 365220 aaaaacagaa ttcggaagtc taaataaagt tattatggga agagtctggc gaatgagaag 365280 caaaactttc cggtagacaa aagtagacca gaaaaattca gtcataaaca atgggaaact 365340 agtaacacca cattccaaca caaaaggaga atgcagcagc agacaagaca gaccaccagt 365400 gatgagaaat acaaattcag aaagaaatga gcacatctta aataaaaata agaatactaa 365460 aaaatactga agaaatatgc aaggtaactt tggaaataaa ggctaatttt attataaggt 365520 gaccaaagaa gaagcagtat gactaaaatt tctactgagg acagactcta gaaaattaaa 365580 aaacaaagaa aatgaataaa ataaacataa ctaaagaaat gcatatcaaa gcataataac 365640 gaaaaagatt aatagctaac tacataaaca taaaaccttt catttggcaa aaaaatccta 365700 taagcaaggt taaaagacaa atgacaaact gggaaaaaat atttgcgaat ttaccagcgt 365760 taaaggacta atctccttaa catataaagt ttctaaaagt gaagaaaacg accagctgag 365820 cagcaaaatg agcaaaagac tatataaaac tataaacagc tctacaagaa aaaatgtcca 365880 ttatcattca taattgaggt aagctcaaaa attgtaacta tagtaaaata ccatttctca 365940 attggcaaat aagtaaacat ccacatttaa caacacattc tgtttggaaa gttttaagaa 366000 aagagatact gttgtaaact gctggtggga atgcaaaatg ttatttttct gtgaaggagg 366060 atttggcagt atctagcaaa attacacatg catctaccat ttgatgcaac aatcccactt 366120 ctaacaattt atcttaatga tactttacat atgtacggaa taatgcatga acattaagag 366180 gattcactgt gacattagta ctaacagcaa aaggttaaaa ataacctcga tgcccataaa 366240 tattgataag ctatgctgca tccacacaaa ggagcagtat tcagtcatac aaaacaaaat 366300 ggaaaacacc tctgcaataa tgtgggatga ttctcaggat acactaggaa gattattttc 366360 ctagttctgt cctctgataa ggcctacaag cagtaacgtt caaaagcaaa ggccatactt 366420 tgcatctaaa atctgacttc taaatgccat tctccaacaa tttattggaa aaataactta 366480 ttccaggcct gagaatgaat gttcgagatt agttagaaat ctcaaaatct aatagggtca 366540 ttttaaaagc acacgatagc taagcaattt gaatatcatt tagagtaatg actgtgaaac 366600 gtattaaata caaaaacatt cattagttcg taatattcaa aaaggcagca aaaaccaacc 366660 aaaaaacaaa attaaattgt cactattaaa attattacat taactcctta ctctaaaaac 366720 cttaaatcta ttttatcatg ccttttctgt agaactgttt ttcaaggtaa tcaaatggca 366780 cccaatgatg agaaaaaaga atgccaggta tatatgtagg acaagcagat ggaaattttt 366840 tttccccaaa cagccatttt gcaatcccca atgagataac agattaaggt aatgatactg 366900 ataaatacga aaatcaggtg aagggcaggt agcaggttct ggaaagatga tgatggcaac 366960 gacatagtta ttattattat tattttttgt tttattccct cccaacctcc cctacaaaaa 367020 cagcaaactg aatgagaaaa ccaaagaccc agagacatta tctacaacaa aaccatgaac 367080 cattgcatat aattggacag aaacaaagct ctgacaacta caagactggt tagtaaggaa 367140 gcagatgcaa ggtaactgac tgggtttctg acagccctga gaacactgcc aacccactgg 367200 aaagcacagg ccaatctgaa aacagggctt aaagttttaa aaagttctac aggatctaat 367260 ttgcagatga ttacaaaggg atcatgatgt agtaagctct gggcccttaa aacacccgaa 367320 taccaaaccc ccaccagaaa caaaccttgt accgaggaaa aacttctggg aataacttcc 367380 gaatggacca ggtcagtaat aaaaaccaaa aaaaagttca aatatatgtg tgggatagag 367440 gagtaaagaa ggcagtttca gaaagcacaa gggcatattt ttgaccattt tacaaaaaca 367500 cagacttctc ctcgtcccta aaaagcgaaa aaagttatcc tggcccatct ctccctcgtc 367560 caagtatgag aaactcattt cactcacaca cacacacaca cacacacaaa taaataaata 367620 acagaacaga gtgaaacagt gtaattatta gagaaaaagt atgtgcatat acatgagaat 367680 ggtgtcccta cagaaaatca aagtacatga aacaatatgc aaataaaaca tgaaaactgt 367740 aaacaaattt caaactgagc taaaaagaat ttaaaaaata acaaatcatt agaaatggga 367800 aatttctgaa tgagggtaac tgaaaaaaag gaagacatga cacaactaag gagtaattag 367860 aaatgcaagg aaaaaaatcc catcaaatac aaagaaacta aaactaaact agaagaaaca 367920 taaaggtgaa taaaacagaa caataatacc agaacctgaa ggcagaagaa aaatcttaaa 367980 atcaaaaaga aacaaaccca tgcttgagac tctccttgct ggtccagagc cacagtgctg 368040 ctgtgtactg gcaggaggaa ttctgctata attggtcctg gcagtgttca cctttcctgc 368100 aagtgttcca cagcccaggg acacaatgtg gtcaggagca ctgccaggaa caccagcaag 368160 ggggagcctg ccacaacagg cacaaggctc aggaagcact ctccagccca cgaaaatcta 368220 gtgggggtcc tcttccctca cccaaacaca ctctgcgcag ctcagcctgg agaaggcccc 368280 tcaagcagca ctactaggaa ccagtgcgag ccccagtgga ctgagataaa agcaacaaac 368340 caaaacagca ccataaagcc tctgaaaaat ggtcactgga accacagctc acaaatatat 368400 gctagtacct acatgctata ccttaacagg ttactactga agttaaaatt tttaaaaagt 368460 acagagtctc ctgatataat aactaaaatg tccgagacac aatccaaaaa ttatctgtca 368520 taccaagaac caggaaaatt acatgaagga aagaaaacgc caacactggg atgagtaaga 368580 tgctgaaatt atctggcaag gatcttaatg ctgccatcag agaaatgatt tgacaagcaa 368640 ttacaagttc tactgtttca aaaacgaaac aatagaaaat ctcagcaagg aaacaagata 368700 caaggaaaaa aaagcaaatg gaaattatag acctaaaaaa tacaatagga gaaaaataat 368760 cattagatgg gctcaacagt agagtgaaga tgacaaagga gagaaatctg aacaaaagag 368820 agaaaataga ctgaaaaatg aaccatgcct caggtccatg tggaacagta acaaatgact 368880 caacatttgt atcattagag gcctagaatg gagaaaagag tgacgctgaa agaacacctg 368940 aagaaataat ggttgaaaat tttccatgtt tggcaaaaga cacaaactta cagcttcaag 369000 aagctgagcg aaccccaaat agcacaaata aaactattct ttgggaataa agggaaaata 369060 aagtcatctt cagaaagaga aaaacaaaaa gaatttctca ctagcagaac tgcctttgaa 369120 gactggctaa tggaagtaat aaaagatgga atcttggaaa aaataatgga aatagcagaa 369180 acatgggtac atacaacaga gcatcactcc cttgataagt tctataagtc atattggata 369240 actgatacaa aaactgtaat agcattaatc ctcaaaacaa tactatttaa aagtggggaa 369300 agagacccaa ctgaaattaa ggtttccata tctcattcca tgtaatggta ttgatggcag 369360 tgaatggtgg taagtcacat tatctataat gtgataccca caatgaccgt gaaaacaact 369420 ataaaaaaca catagaaggc caggcatggt ggctcatgcc tgtaattcca gcactttggg 369480 aggctgaggt ggacagatca caaggtcaag agttcgagac cagcctggcc aatatggtga 369540 aacctcatct ctaataaaaa tacaaaaatt agccaggtgt ggtggcatgt gcctgtagtc 369600 ccagctaccc aggaggctga ggcgggagga ttgcttgaac ctgggaagcc gatgttgcag 369660 tgagctgaga ttgtgccact gcactccagc ctgggcaaca gagcgagact gtgtctcgaa 369720 acaaaaacaa acaaacaaac aaaacaaaac ccaaacacta aataaatcaa gggtcttaaa 369780 aatcttaaaa aatgttcaag taatcatgga aggcaataaa taaataacca taaacagaag 369840 acagaaacag aaaacaaata ataaaatggc agacctctcc ctaacatatc aataattacc 369900 ttaaatataa atggtctaaa taaaaaaatt aaaaggcaga gactaacagt ttttattaaa 369960 atgacaacta tatgctgttt acaagagatt cgtttcaaat tcagcaacac aggatgaaag 370020 taaaatgata gtaaaagaca gatcatgcaa acattaattt aaaaaaaaac aaatggttac 370080 actcatatca gattcagagc aaagaaaatc gcaaaacaga aaaaacttat ataatgataa 370140 aggaccaatc accaagacat agtaattcta aatgggtatg aaccaaatga tagagcctca 370200 aaataaatga aacaaaacct gataaacaga taaatctcag aagcagacct atataaatat 370260 tctcaagtga tttttaacgt atgtgaaaaa aacaattcaa tgaaggaaga acatacctag 370320 aaaatacata aggaaccctt aaaactcaac agtaaaaaac caaatggact cttggttttt 370380 aatcccagag aaatacaaac tttttgttta caagtaacat cacagttaat ggtaaatatt 370440 atagtctctc tcaataaaat gaggaataaa gtaagaatac cttctaccaa aggttctagc 370500 cagtgcaata gaggaacagt aataaataac ataaacattg gaaagaaaga aacctgtctt 370560 gatttgtaga tgacatagct gtttactaga aaaccctatg aaatctacta aataactact 370620 agaataagtc aatttagaaa ggttatagga tataagatca atatataaaa atcgatttta 370680 tttcaagata gtaataaaca agtgaaaagc agtatttaaa aaataccact aatagcatta 370740 gaaacatatt ttaagtttat tcctaaccaa agagtacatg atttcaacat taaaaactat 370800 aaaacagtgc tgagataaac taacaaacat ctaaataaat ggagagacgt acggtgttca 370860 aggattggaa gaatatattg ttaaaatgtg aattctctcc aaattgacct gccccagtca 370920 aggcaaccca aatcaaaatc tctgcaggct ttgccctttt gtttgtaaaa attaactgat 370980 tctaatattt atatgcaaat aaaagtcaaa gcaacctaat gaaaaagttg tgggactcac 371040 agcatctgat ttgaagctgc agtaaccata acagtgtcat tttggcaaaa ggacaaaaca 371100 aattaataga acagaatgga gaatccagaa acacggctca cacacagatt gattttcaac 371160 aaaggtgcaa aggcaattca atggggaaag aaaagtctct ttaacaaatg gtactggaac 371220 aaataaataa aactatttag aaaatgaatg acatccactg tctaacagca tcacaaaatt 371280 ttattggtgg tggatcacag atttacacat aaaagttaaa cctatattac acaattagaa 371340 gaaaacataa gatatttgtg gctttgggct aggcaaagat ataaaaggac ataaaaaacc 371400 ataaaagaaa aaataaatta gacctcaaaa aatgaataat ttctgctcac cagaagacac 371460 ttaagaaaat gaaaacttgg agaaaataat cataaactac ttatcagaaa tgggcctttt 371520 atatagaata tacagtattc cccacttacc catggggaat acgttccaag acctccagtg 371580 atgtctgaaa ttgcaaatag tactgaaccc tgtatatact atgcatgatt tatttttcct 371640 tcttcacaat ttcatagata caatactcat ttttaccata gattttagca acctcaacat 371700 atgattttta aattctttcc ttaaaggaag cactttccag cttctctttg gcatatatat 371760 tcgaatttcc aacatcactg ctcttgtgct ttagggccat tattaagtaa aataagggtt 371820 acttgaacac aagcatgtga tactgcaaca gtcgatctga taaccagtag actaaaagtg 371880 gtgggtagtc tagacaacaa cgatatactg gaaaaaggga taattcatgc cctgggtgga 371940 aaggtgggag atttcaccat gttactcaga atagcatgta atttaaaact taagagttgt 372000 tggctgggtg cagtggctca cgcctgtaat cccagcactt tggaaggctg aagtggaaga 372060 attgctagag tccaggggtt tgaaaccagc ctgggcaaca tagtgagacc ctgtttctac 372120 aaaaaaataa ccaactaaaa attagctgca cacctgtagt accagctact cagagggctg 372180 acgtaagaag attgcatgag cccagatact cagaggactg aggtaagaag attgcatgag 372240 cccaggagtt tcagtttata acaatctgta gtcatgctac tgcactccag cctggatgac 372300 agagactttg tctctttaaa aaaaaaaaaa ccaacgaacc aaccaaccaa ctctccctgc 372360 cctgcacccg ccaacacaca catacatcaa aaaccctgaa ttattcatgg aattttctac 372420 ttaataaata tttttggacc actgctgacc aaagataact gaaaccaaaa aaaagcaaaa 372480 ctaaggataa gacatactgc tatattttaa gaaaatatct atagtcaata gaaatacaaa 372540 aatccaatat taaaaatgag gaaaagacac ttttagttaa atatgcacct gctatatgct 372600 ttggaaactc cactcctaca tgtttgccca ggagaaataa aacatttcca caataagact 372660 acacagcttt attcacaata gtcccaaact ggaaacaatc caactgtcca ccaacaggta 372720 aaaaaaaaac actttgcgta ttcatataat gcaacactac tctataattt tttaaaaggc 372780 actataaatc aatgcaataa catggatgaa tctaaagagt cttcatgcag tacaagtaca 372840 taagattcca ttcataagaa attctagagc agacaaaagt aagctacagt gacagtaatt 372900 aggacagtta ttgtctgttc taatggggga tggagattca ctggaaggga aaacatggga 372960 actctgtgct gatggacata gtctacacct tgactgaaat atggttacat aaatgtaatt 373020 tttaaaaact aacccaatta agccctgggt atttcactgt attcaaattt taccccacac 373080 aacatcgaca ccaccattat taccaccaca ttgataacat tcagagagca gttagggaat 373140 cacattattt tgaaaattag taagtaatgg gaaagaatta agcattatcg tatatgatat 373200 gtacatattt atatacatgt atacagatcc tatatgtgga tctgtaattt agggtagtca 373260 tagagttgat gagaaagagt ttttcttaag aagtattaca ggtaataaag gaaggaggaa 373320 taaagaattc gagtatcaca attttgtaac cctcaatgaa ttagcagatc taggcaatca 373380 gaatccacga taaaaattac tagaaaagac agaaagcgag tgagactttt aagttattcc 373440 tacaaaccaa catctatgaa gtatttggga aggaaataaa ctctgaatct gtttttcgtt 373500 tttttgagat ggaatctcac tctgttgccc aggctggagt gcagtggcac gatctaggct 373560 cactgcaacc tccgcctccc aggttcaagc gattctcctg cctcagcctc ccgaggagct 373620 gggattacag ctgcctgcca ccaaacccag ctaatttttg tatttttagt agagacgggg 373680 tttcccccat gtttgccagg ctggtctcaa actcctggct tccggtgatc tgcccgcctc 373740 gggcgttttt gcatgtattt tttcaggtgc tgaaaaagct ctccctgatt tcatttcttg 373800 ttgactgctt agagacatct ttccaaatgt ccttccttgt cactttttca aagttaggag 373860 cagggattgc acgttttttt gattggtaat ttttgtttca aaggtttgat tcagattcag 373920 agttgatttt gctaggtatg gtggctcacg cctgtaatcc cagcactttg ggaggccgag 373980 gcgggcggat caccagaggt caggagtttg agaccagcct ggccaacatg gcaaaaccct 374040 tatctctact aaaaatacaa acattagcca ggtgtagtgg tgtgcacctg taaccccagc 374100 tactcaggag gctgaggcag gagaatcact tgaacccagg aagcggaggt tgcagtgaac 374160 tgagactgcg ccactgcact ccagcctcag tgacagagca agactgttta aacaaacaaa 374220 caaaaaatta acaaaatctt atttctagtg gtttacatat taatgatgct ggcaactttt 374280 agttgaaatg tattaaacag cctcgcagtt tttattttta tgaattctgc atacaataaa 374340 taaataccaa ccaaaatatc tatacaggca taccccagag atactgccgg ttcagtttca 374400 gaccatggca aataaagtga ttatggcagt aaagtgagtc acacaaattt ttttgtttcc 374460 cagtgcttat aaaagttacg tttacattat actgtagtca agtgtgtaac agcattgtct 374520 aaaaataagt acattatctt aatttaaaat cattgctaaa aatgctaatg aagtgagcac 374580 attttgttgg aaaaatggtg ctggtagacc tgcttgatgc agggttgcca ccaaaaaaac 374640 tcagtatctg caaagtgcaa taaagtgaga tacgcctgta atgtcttttt tctcttctgt 374700 tattacaagc actactttaa gtcttcaact accgaatact tgtagactat ttaatgaatt 374760 aatattttca tcatatttat attgagaaaa ttaagaagct gaatttagtt agaaaaggtt 374820 tagaatatca tcaactcttg aggatgagtt ggaagctact ttatctgtca tttttcacat 374880 aacactagtt tgcccttcaa atcatacatt taaaaatgat cttaagatac ataccaagta 374940 gggattatgt tgttataaaa agctagaagt aaaattaaga ctttaatttc aaagataatt 375000 tctctataaa gaatagcaca agatatgttc aactattctc agagatgcat caagatatga 375060 ctttttttcc tactagaaat tatatctatg atcaatcata ttacagagat attgctgtta 375120 tactccttgt gactgatgag gggggttttt cctatcacca tgttatccca accctttaat 375180 gaatcacctt tgaaactcag aacaggtagc agcacagagg ttgctaagag taaatacatt 375240 caccactgct gccagaaatg accaacggtg caccagaaag aagaaatact ggtgaattcc 375300 cacataccac gacgaacaac cttataaaat aacagaacaa atgaatataa agtaacatac 375360 agccatccct tggtatatgt gacagggatt ggttccagga ccacgtgtgt ataccaaaat 375420 ccatgcacgc tcaagttctg cagttggccc tgtgaaactg gcatgtatga aagtcagccc 375480 tctgtatatg caggttctga gtcccaccaa tactgaatct gctcttagtt gagaaaaaaa 375540 atctgcatgt cagagggccc atgaagttca cagctgtgtt gttcaagggt caactgtaat 375600 ataaaaataa catttattgc tagatagagt tgatattcat tctagtgttt atatacttga 375660 gtcttagagc aatagccttt ggagacaact tccaggaagg tacgtgtttg catgccttct 375720 cactgcaatc catcagtagc tgccacttga accagtctta gcaggggatg gggaagccta 375780 tgtctttcag aattggatga tgtagtacac agaagtagac agtagagtag taagggcatt 375840 tgcttaaaag cagatagaac tgggaacctc tacatctttc tgtgagaatt cagggcttag 375900 ttttttaggg tgtaaaatgg aaatactagt atgtatctgg acatattatc ttaagaatta 375960 aataaaagac taccatttca ctcaaaaagt gcttgatcct gggaagccat gtaacagttc 376020 acaaatgcag agttcaaaag aaaggaaaaa ttgcagacat ggtagcctta ttttaattat 376080 cttctaacca gcagtaagca tactctaacc agtgaggaat actagataat ccatacgcca 376140 aatgcaggag attacatgag acttatatat aacaacactt cattcatgaa ataaatcaca 376200 agattagctc tgaaaaatgg tgattatatt acaaatacaa atctaagtat atagatgaca 376260 atttgtgagt ttgcttattt gggaattagt acctagagat aaaggtctga agcaaaatca 376320 cacacccctt tggtgaatca aatcttcctc tgaagaacta agtacctcac ctaatcagaa 376380 cagagtccct ggtatagcca ccgtcatatt ctgtagtttc ttctagtgct tggaaatcta 376440 gattctgcaa attcaagaaa atatgtctta gttatctgct atactactgt atcattacaa 376500 acaataaatc gatacatgac tttttgcaga cacctgcttt cttacccggc ttccacatat 376560 aagcaattca atttcttctg gtctgaataa gtactttaag ggagattcat tggtcaccat 376620 atgaaaacct ctccgaaaag ccttgaactg tttttctact gatttattga gaatgtagtc 376680 agaataaaga ttgacaaatt cctgtagaaa acattaatca caagaacttc ttataatatg 376740 ctatgcaaac aaaacacaag ttattgggct gcatagcttt ttaatttttc caagaaaaaa 376800 acattcaaga atattcttaa aaattcaatt ttacacctac ttcttaacaa tttcacaatt 376860 ctctgttata gccaatatta agctatgaaa aggccatata cataaaactg tcaagaatat 376920 tcttaaaaat tcaattttac acctacaaag aaaactactt cttacaattt cacaattctc 376980 tgttacagcc aatattaagc tatgaaaagg ccatatacac aaaactgtca tacttataaa 377040 tgtcaatttc gataatgtat taaacagaac tgaatataaa tgctggagac gcagaaaatt 377100 ctttaggttc tctcaactag gtatgtaaac agacacattt aaaccatgta tccatctatt 377160 tataaatgcc aaccgtttta agagagtaca atatatttga tttaagcaaa ccaggaagtc 377220 ccaagttttc taccatagaa tatttggtaa gctgcctact gtatccagtt cagcaaaaat 377280 gtggaagtac tgactgacac ataaactact gtatcaaatc ataaaaggaa aatgtgcttt 377340 gtacccttag tgtgtataat atttaatcaa aaaattatat caatataaac atgtttctta 377400 aaggtatact atatatttgt cataattttt tgcttgttat gttctgggtt attcccattc 377460 ccgatgaaca cattttagtc aatagaaacc caaatctgac gtaaagtata cttttcagaa 377520 atgtattttt atcacaaaca ggatatacat gtgtaaatta aatgtaattt ttatttgttc 377580 tgtgataaag accttaatca tgaggttcct gcttacagct taatacaaga aacaccctgc 377640 ttcttgcttt atactacaac cacacttagc tattaactat ctcctgcttc atgtcctctt 377700 tctctaaaag gggctttagt gcccaactgt gtgctttcat accaacttat atccaagatt 377760 tagaaaagtg gactctagca tttacataaa cttagttact tgtttttttt ttgtacagac 377820 tatattagat acttctttaa aaattataag catacatgct ttgaaagtgt taatgaagag 377880 acaaaatgtg acataaaaac atttattacc ttcctgtttt catttgtaat tggaatttta 377940 tcaccatttt cctttagatc atacatcatt gggttaccaa aaagatctgt ctgtgatatc 378000 tggaaagtga tcatcatgtc atcttccaca ttcccttcat actccaataa atcttttaaa 378060 ctctgatata gaacctagca accagaaatg gtaaattgag gccaccatag aactacaaaa 378120 tacaacaaat aatttatatc actcttctta gaagacaaca aaaatcttat caataaaaat 378180 tgtaaaaagt gtagacagta tccctccagt cccccaaata gtttccaacc tataaaagaa 378240 agattgtcag tcactgtgat gtcccattct ctgctgagaa accccatacc accaatttag 378300 caatagaatt cacactgtgc tctatgagaa attctgtggt gtctcaaggt gggggtgggg 378360 gtggtaggag caggcacact cgttgtaact accaagaccc ttagccaggg ctactctgat 378420 ttttacctat ctcttaagat ttcactaaaa cacaaacaaa atgtttagaa acacttctct 378480 atgaaatcaa tcttacaaaa gcttcgtgct gacagcaata tataaaaatg tccccctttg 378540 agtttttaag tgtttctggt acttcggtca gattaaaaca tttttatctt attgataaga 378600 gtatcaacaa agattctaaa caaaaacttt aaaattttga cataaattaa atttttgcat 378660 ttaaataaaa tctaagagac tgaattaaaa aaatgacaaa gaacttactg ggtgagagtc 378720 tcccaagtca cgaaaagttc cttttttccc cattagcttc ctgtagacaa ccatgggaaa 378780 atgtacatcc agtatacagt tattgtaaat agccagaccc agtactatgc caatcagagt 378840 aaactgaccc tcagtttcaa aagaagatgg attaaaccaa aacaattttg tagattcatc 378900 gtatgtgaac atacctataa gaaatgattt ttaaaaatac attacttttg tattttatta 378960 aggactgatg aataatacaa atataaactt aaaataatta tgcatataaa acatttaaaa 379020 tatatgtaat taggcatgca acattgattt ctattatatt agcacttgag aaaacaatgt 379080 ccacatatat ctgctataaa ttggggtgaa tggtgatatg taattttatg aagccaaagg 379140 aataaagtag taagtaattt ggtggcatcg ggtagaaaaa tacgttaatt aaattcaagc 379200 tttctaattt tctactaaca cataagaaaa gttatattca tgctttatcc acccatagct 379260 gaaaaataaa cataaaaaaa caaaaaatgg ctacatttcc aaagtgtttc atttataaaa 379320 atataattac ttatatctgt accacacgta ctatttttga aaacaatttt tcattttttt 379380 ccttgagatg gagtctcgct ctgttaccca gggtgggctg gagtggcacg atctcagctc 379440 actgcaacct ctgcctccta ggttcaaaca attctcctgc ctcagcctcc tgagtagcta 379500 ggactacagg tgtgcaccac cacgccagct aatttttgta tttttagtag agaaggggtt 379560 tcaccatgtt tgccaggatg gtctcaacct cttgacctcg tgatctgcca gcctcagcct 379620 cccaaagtgc tgggattaca ggcgtgagcc accacacctg gcctaaaaaa caatttttaa 379680 tcacagtaaa gaaaggttcg ttttttcaaa attagacaat ggtgccatga aatttttcta 379740 gcattttcct aataaaatca gatgatctga aatacataaa cctggataaa tctgatgaac 379800 ttagataaac aaagctattc aatacacatg ttaattatgg gccaatacgt aaaagaaaag 379860 tagtttcgta gtctttcaat ttcacatggt cttcactatg caagccccaa tcatggaggc 379920 tttttttttt tttttttttt ttgagacggt ctcgctctgt cgcccaagct ggagtgcagc 379980 agcactcagc ttagtgcaag ctccgcctcc cgggttcatg ccattctctg gcctcagcct 380040 ccggagtagt tgggactaca ggcgcctgcg tggaggcctt ttttatatca ctcattggaa 380100 aattggggcc cggtgtggta gttcacacct gtaatcccag cactttgggg aggctgaggc 380160 aggcagatca cttgagctca ggagttcaag accagcctgg gcaagatgga gaaaccccat 380220 ctctacaaaa acacaaaaaa taagctgggt gtggtagcat gtgcctatag tctcagctac 380280 ttgagagggt gatgcatggg gatggtttga gtcttcagcc tgggaggtgg aggttgcagt 380340 gagccgagac agaaccacta cactccagcc tgggcctcag agccagatcc tgcctccctc 380400 caccaaaaaa taaaagatta aaaaaaagga aaattggaat ctttggaatg agtactacta 380460 aaaattgatt tcttcccttt taaatgacta aggaaaaaaa ttttaattga atttaaatca 380520 ttttactaca tgtttagttg ctactgtgaa acaatgaaaa catcttaaga attaagtctg 380580 aaaaaaatct gtaatttcca atagaaaagt agagcttaga aatcagaaat caaattatac 380640 agtatataag tattttaacc tgtttataag aattttaaaa tctttgaaaa tgtcattgtc 380700 actttaagtt taaaaataag gagctttaac atgtttcctt gatcactagg agtatgaatt 380760 aagcttagga cattttctga atgcaaaatg gtttgaaaat taaacaattc atatttgagt 380820 ttcatggttt ctatctaaac atttttttta caggccaagt tacaacatcc atggaaatgc 380880 ttttagttat aagtatggta ttaacaggat caagaacagc tgacaaataa ttacaattaa 380940 taaatttgtt caagctgaca atggtgtgtc taaaaaatta atgaatttaa taaaatgtca 381000 caaatgccct tccttggaac caagagcaac aagctataag ttaatcagaa tataactctg 381060 aagttccatt ttaggcacat tttctcatgt tccagggaga aaagcaccat aacctcctgg 381120 taaaatactc ctttttgata cttctactgc catcacttca gttatcttac tggaactgct 381180 taatctatgt tttttcttac aagtatttct gcatataatg caagtatgct ttatagctaa 381240 ggtttaacat ttctagatac atcaaaagct agagctaagg tttaccaaat ttaagaactt 381300 tatgaagttt ataattttct atctcaaaaa gggcgtcgtc ttatgtatct ctgatttact 381360 tagaacaaac tacatacaaa tggcatagct ttttagttat taataaaaca ctagctagat 381420 tatagataag ggatgcgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt 381480 gactaagaac agtaacagaa aggtcaactc aattagaatc aacaggctat aacagctcaa 381540 atctcaaagc tgaagggaaa tgacatacat tattctatgc acactcctca caattctgat 381600 ggtaccttca gtggaaacct tttcctgtaa ttgtcatgta ctcaatttta aacgtaagca 381660 agctcagtta ctaagtggtt atatttacag tagaaactga accagttcag aattatgaag 381720 ttaagtagac tacccaaaag actgcatctt ttccctgttc tactttatca caaaagggaa 381780 aaaactaaaa ttctgatcct tcactttcaa atttccaaat cccatcagcc tttcccaaac 381840 tgtgttcaat aacaactctt ctgttagggc agaaaaagag ttctggagtt caaaaagttt 381900 gggggaaaca ctacctatat taagccccaa gaaatcttat agcaaataaa cctaattaat 381960 gtgatatcag ctagtgtttc tgaactttga gcatgacata cttgtgagac agtctctcaa 382020 tactcttcaa accattgttc tttgaagttc acaggtcagg aaaaccgtga gtttgatgat 382080 ggttttagac aacaaaaagc aaagaaatcc ctccaactgt tccaatatac cattctaaag 382140 tgctttcaat tcagtttacc aaagagataa tttccttcat tagaatattc cttctaagaa 382200 ataaaagaat ttgaataaat tagtgataca aatcagttcc taaaacctac aaattcagtc 382260 atgatgtgtg attctgggta atccatacca aatccttctt ttgctgctct tcatagctga 382320 aaatatttac aaagtaagat aaacaaataa ctaactcaaa agatgatacg acaccataat 382380 cacattacta atgtatttac caatatctgg attgaagatt tcctccacaa ccagctgaaa 382440 aaattctttg gaaacacctc cctcatcaac tccttgttct ccttcaaatt ccacatacaa 382500 ctgcttcttc aagtctgcag gattttccat agcgatcatc tctagctagt gattgaaaag 382560 ataaacatga aaagaagatg attgctagta tcaggaaaaa aacaaaataa aaacaaggag 382620 taggattagg aaacaaatac aaatttttga ctttttgtat gtaaatggaa acagaaagca 382680 aactgataaa aagccagtga agacaaagat tcagtcttaa agataatcaa aaagacagac 382740 acaaaacaga cactagcata gtaaaaagct aactttactg atttgttatg aaattaacat 382800 acaattaatt aagattttat tacttgtgtg ttaagtctgg actacacagg acatggaaaa 382860 gcagctaaat catttcagca aaaacaatgg agtagaggtc taacctcaaa attgttcatt 382920 agtagtcctt tattagaata gaaactcaag ggttaagtct tagtatctac taagtcataa 382980 gtaaaatatt tcaattaaga aaaatacact gaatactaaa gcagtttatg gtctctcaca 383040 gtaagactta gtataaatta ccacctttta atggactaga acccatctta tatccacatt 383100 tccttaaaaa caggtgagac ataaccttac tcatgtcctt actctttttt tttttttttt 383160 tgacatgaaa tctcactctg tcgcctaggc tggagtgcag tggcgcgatc tcagctcact 383220 gcaacctccg cctcctgggt tcaagcaatt ctcctgcctc agcctcctga gtagctggga 383280 ttacaggcag gcgccactac gcctggctaa attttttatt tttagtagag atggggtttc 383340 actacgtttg ccaggatggt cttgaactcc tgacctcatg atccgcccac ctcagcctct 383400 caaagtgctg ggattacagg cgtgagcaac tgcacccagc ccttattctt aaattgtaag 383460 ttaacaaact ttagtgtcta gcattttctc aactataaat cttttaccaa atatttttgt 383520 gtacctatag aattatgaat atacagtaac ctcattgaga ttaatcataa aatcaacact 383580 agattccaat attaactgtt tatactgcat tttgtttgtt ttactttatg tatctaaaat 383640 ttgctaacag tatgactgta tccagtacat ggatggatac tgtatctagt acatggatgg 383700 atactgtatc cagtatccat catatctcct aacttgcctt caaacatctg ttggctggtt 383760 aaaaaaattt aatcttggag atgaaaattt accaaaacag gatattaaat gttttcaggt 383820 tattccaact atttcaaaca gaattttaaa aatggttttg aaaaatgcaa taatcactga 383880 aacaactgta acacagcact atagtagtta aagtaataat actcatttgg acaatctagt 383940 ctgtctacaa aaaataaaat ctcataaatt aacgcatcag gtcaggttgc ccgagagcat 384000 tgttttttca aacttgtcac ctgcaactca ttagtgggta gtctaatcca tttagtggtt 384060 tgcaatcagc aatgggaaaa tcagaatgca ttccacatag taatggaacc tactgttttg 384120 tgaaactttt gtttcaatta gatgtacaga tggataagca tgtactggga tgctatgtaa 384180 aatactaggg attgcagtca aagagtttga caaaactagc tgaaattatc ttctgggtat 384240 cttcaacttt agggtcctat tctgtgaatt tagtctttag ctttaaataa tgtctgttgt 384300 tgttcaacac cgatctctaa tatttacaaa atcattttta ggccacacag tttactttta 384360 gacaatgttt tgttatggaa agaccaagag tcagtcagaa ttcaccttac tagtcccaac 384420 tctcacttac cataactttt aacctttaaa ctttagcacg cgattcaatt aagcctcagt 384480 ttcctcaaca tactgtaagt tgtgaaggct tattaagaat atatgagaac gagtgttacc 384540 ttttaaaata gttttgctct ctgaacaaca gatttgcaat tttgtgtccc caaaggaact 384600 tgatatagac tagttccaag atctagagtc aaacaaatgt agatgtgaaa ataaccttgg 384660 ggaaaaaaat agtttcagtt ggaaacctgt ttcaagctac ggagtataca gaattctgag 384720 gagactaaaa ttagaattaa catcttagct caaatgtggg accaggccaa cattccatat 384780 tgccatgtaa tccattctga gtttccttat gccagttccc aactggctag gtgttaaaga 384840 tgtaagtcag tgtttatatt tacctttaca tccaaaggta tacttgcttt tatcaaatat 384900 aatgtattcc aaagtgggga aaaaaaaggt tatctggtat ttagactgtg cattctacag 384960 cttttcccca ctaacattca tagatgagag ctgactcctt atcaatgtaa aaccttttaa 385020 aggatgtggt ggtgaatttc tacaggattg agaggccctg tgttctatct agtcttagct 385080 ctacctaaga catgtcaaat gataactgaa gcaaatttat ctttattctc cataaaatat 385140 tacatgtctg tccacttcca ctgatctcta ttctatgctc cccaccttgg tgccaaaaga 385200 atgtaatgca atgcaatatg ttctattgta aatgcaaaca tacaacttta cctctcttat 385260 ttcatctgta aaataaccat aataatatag taataaatta atgtatgaac tgcttagatt 385320 aattccctgc ataaagttag tgcttaaaag tactagctgt tgttgctgtt attttattgg 385380 ttctaaaata ttttctgaaa acctaccata gcattataga acaaaaatat tccatgaata 385440 cagcaacaat aatatatagc acttttgtag catttcacac atagcaacta atttaatctt 385500 cacaacaccc ttatgaggaa ggaaacatta actccacttt acagataagg accccaagat 385560 actgaaaggt gaaataactt caagtcacag taagtcacag taagttgtgg aacagagata 385620 ctaatccagg aaacaagctc ttaactacta tgctttactc actctcttca atgacgacca 385680 aaaatttttt ttttaggatt atgagtgatt tttattttcc ttattctttt ccatattttt 385740 ccatttttta caacaaatac atttttcaga gtcagaatgt gttcaaatat aaatatgtaa 385800 aaagaataat ttgaaaagta gttggtaact gaattctgta ggcaaaaatt ttgttattac 385860 ctattttaga ttaccattct ggtacacata agtgatttca taaaatactg taccacttaa 385920 gaataaaggc tgggcgccgt ggctcacacc tgtaatccca ccactttggg aggccaatgc 385980 aggcagattg cctgagccca gcagtttgag atcagcctgg gcaacatgat gaaaccttgt 386040 ttctacaaaa aactaataaa taaataaata aataaataaa taaataaata aaaaatagtg 386100 gggggtggtg gcatgcgcct gtcatcccag ctacttggga ggctgaggtg ggaggtcaag 386160 gctgcagtca gtagagatcg tgccactgta ctccaggcct gggtgacaga gttaagaccc 386220 tgtctcaaaa attaaaataa ataaaatagt aaaaacagaa tacataaata gcctttaaaa 386280 ctattttatt ttaaattatt aacacataaa atttagcaat aaccattttg ataaaggcca 386340 ttattgcata aacagctgta ctgataattc tttttcttaa aaataacctc catcaattgt 386400 tcggtcaatt taaaaaagat ttaacaaata aactgtaaag gtgtattctt tacataatag 386460 ctatattatt taaaattgta tgttgttgtt taaacccaaa cctcaccata aaactgtatt 386520 ttttaagtca gaagttgttt taaatgcatt aggatatttg aaatttggag gactatgtct 386580 aaacattctg aaaaggagaa cgtgcatgca tgcctgaatt tatttacaat acacacgtgg 386640 atttttaggg ttttttttgt ttgttttttt tttttttttg agacggagtc tcgctctgtc 386700 gcccaggctg gagtgcagtg gcgcaatctt ggcgcactgc aagccccgcc tcccaggttc 386760 atgccattct cctgcctcag cctcccgagt agctgggact acaggcgcct gccaccgcgc 386820 ctggctattt ttttttgtat tttttagtag agatggggtt tcactgtgtt agccaggatg 386880 gtttcggtct cctgaccttg tgatctgccc gccttggcct cccaaagtgc tgggattaca 386940 ggtgtgagcc accgcgccag gccaattttt aggtatattt aaaagtacag tgtatgttgt 387000 atttatttaa catggagact agcaacagac agagattact ggggaaaaat aaacaaaaat 387060 atcctggata taatcatatc tacctcttca ctgcgtaact tcctcttctt taagactctt 387120 gatttcatca attgctggat aaaatgattt ttaatttctg aactttttaa ttggccatga 387180 tgatgaaatc ctagggagtt cattttttaa aaaaaaaatc tgacctgata tcaaagcatt 387240 tgcagaatac ctagcaggat gacatcttaa tatcaaaata tgatattact agacttacag 387300 gaatcaaaag gaaaacctta tcacttaaaa tcttatagtt ttctgagcta ttacatcaaa 387360 tcaattcata attttttaaa aaaattcctt aataccatga atatttaagt agaagcaata 387420 atcagataaa agagacctct aatacttaag aatgcctggg atttctaaga aaggctagct 387480 tcaaggccgg gcgtggtggc tcatgcctgt aatcccggca ctctgggagg ccgaggcggg 387540 cggatcacga ggtcaggaga ttgagaccat cctggctaac acggtgaacc ccatctctac 387600 taaaaataca aaaaaattag ctgggcatgg tggcaggcgc ctgtagtccc agctactcgg 387660 gaggctgagg caggagaatg gcatgaacct gggaggcggg gcttgcagtg agccaagatt 387720 gcgccactgc actccagcct gggtgacaga gcaagactcc gtctaaaaaa aaaaaaaaaa 387780 aaagaggaaa aagaaagaaa ggctagcttc aactacttca gtcaacttga ggcttaaact 387840 attgcttgag atttccagat tatccaaatt aattttttca tgttcacgat aaacacatga 387900 agaaaagtct gttatatctc aaatgtagtt taaatgtttg ggtaacacca aatcacataa 387960 tcacgttcgt ccatgagacc tggaatcctg acttctattt ccaattctgc cattaattta 388020 tgtaggctgg aatctctttt agatttcatt ttcctcacat gtaatactaa gtttgatgtt 388080 tcattgtctt aaattattat ataatgctga ggatctatgt atatataggc ttcattctct 388140 cattcagttt ctgagaaatt actttgaggg cataaaccaa gcatatttct tggtttcatt 388200 tttgatttca attagaataa atcacaagaa agaacaatgg aaattacatg ttaaccacaa 388260 tatagtgtat gtgtaagaca aaattaaaca tacctagtgc agcacagaat aatctcattt 388320 ttaaagctct gtgagtcaat gaataaataa aagaattacg ttcatgtttc actagtaaga 388380 gtgttcacca atgctggaag ctgggagctg aaaatgctgg aagctgggtt agactaggct 388440 attagaaacc agataaaaag ggccagtgac ttttagaggg gattttgcag aacctcctgg 388500 tagtggggct ttttatctgt gccaatcacc tttatctgtg ctaattccta tttttgaact 388560 tccctattca attccacatc tcagccattc cttttggttt ttagatattt atgtgaaatg 388620 ctagaactcc ctgactaatt ggaaccaagt ttcacatcat catcatcctc tattccaagc 388680 ttgctgtccc catgatcctc ttaaaaatct gagtttccaa aacacataaa catacttgta 388740 tatcaaaatg gcctttctct ttctctctat atatgcacac atacacacat aaacacacat 388800 gcacacacac ccccacctga gctgaaccaa aggccatctt cccaaatatt ggagtctggc 388860 tttatcaaaa tatttgtgga gtattaccag aagttcagat tcataggctc tacaatacag 388920 cttctaatct aaacctctag aggttagggc cctggatttt atttatttat ttatttattt 388980 tttttaaaca attttcccat tcagatgtga aggcagtttg agggacctca tgatggcaat 389040 actatattct tccataaact tataacctct atcttctcct ttaagaagta atttaaaaaa 389100 tcttaataca tactatcatt ggaagtgctt catctaagaa aaatgagaaa ttatctactt 389160 gtaaaagaac acacaaatgg gtatatttac atatttgtaa atatgtaaat atttacatat 389220 ttgtaaatat gtaaatattt acatatttgt aaatatgtaa atatttgcat atttgtaaat 389280 atgtaaatat ttacatattt aaattaaatt aatttacata ttaaattaaa ttacatattt 389340 atattaaaaa tgtaaatttg taaatatggt tttacatatt tgtaaaaacc tcatcacatt 389400 aggaatgtca ttcaaatgaa aggtgaagtc taagctcatg tttatcactg tactgttttc 389460 taaggaacaa taacgaaaaa atactgaaaa taagtcctag gggaactatg gcagtaagtt 389520 aaacgggtag ggtgggggtg ttcttaagca gttctaaggt atttgtgaag agacaactta 389580 tattctattg attctaaaat tcactttttt cacattatct ctgaaatcag attacaccat 389640 acaaatgata gcatcttaca atgaattgct ggtatttttc tgtcttagca gtaataaaat 389700 gatagtgttt cctacaatca gagattagtg aaaatactat caacatgaat tcttctcttg 389760 tcatcaaaga caatttctct aaaaacctca ggaaaaaagc tgctagtctg gtttgaattt 389820 cacaatatat aaaagcaatg aatatatttt tcttttttaa aaaaatccac aattattaat 389880 tcaagttacc actcctcaac agaaaacata caagagtctc atatatgaag tcactatttt 389940 ctgggcttga tttctaaact aaggagtgga taactctaag gtttctttta gctcttaaag 390000 cctaggatcc cataatttta tttatcaata ttaagcttac cacaaagttt ctcatttctt 390060 cttttccacc caaccctgct atacaattcc aaaattagca agtcataaaa aagtggccac 390120 tagtttgttc actgtgatat ataagaatga ggcttaaaaa gcagagatcc ttgggaaata 390180 agatcttgaa aaattcatca cttttgagct ttcatatgag agaataatct taaaccactt 390240 tctattatag aacttctact atgtgttact aaaatatgtg gctttatcat aatcatcacc 390300 tgctgtgaat acttacttca aaaaattaca caggttatca attttactta taagacctat 390360 ttcgatgctg gtttttctag tcttttcaca ttctgttatt tttttaaaaa aaagaaaagg 390420 aagaaaaagc aagggagaaa gaaagttaag agtaaaatct gcttagtgtg agcattcaga 390480 gcccctaagg aagcttctct gtaagcatca tctctttcta ttttcacagt ttattaaact 390540 gcctaacaca catgatttct gaagtgaact gcttttgtgg gctggcaata ttcaagtaca 390600 tatactatct agtgaatcct gatttatgat aggccacact atattatcta attttgatat 390660 aattaagcag aacttgctaa aaacaagtta ccataattaa agagctcaca gttaatttta 390720 cactaacacc taaggcttta aaagcagttg tttccttaaa attctagaat agaatttaaa 390780 atatagaata aagtatatac caagtactta aacttttgtt tttagtcttg ctttactaga 390840 gaaaaaaatg ggggactgag gaaaataaga ctgagtagac ttctgagcga aagacagata 390900 aggaaggtag acaatttttt gaaccctgga atgattctta cagtgtaatt tcattgcctt 390960 ttaaaggcta gacatagctt ttgatgaaga cagctgaagg gatctcacct caagaagcca 391020 aacataaagt atgtagcttt ggcatttgca gttctgctcc aacaatggat agtcatagac 391080 agacctcaac atacctttca taaaacatca ctcacattct tataaaatac cctatcattc 391140 tgctaaacta tgtaaagtaa ggtgctggct gccttatgat cagtcattaa gtgtattaat 391200 tattcatgtg tctcaaaact atgtaagtga aataaaaagg gtaccagaaa gcaagcaata 391260 ataatgactt caggcagtta aagccccctt ttgtctctgc tagaaaacca cctgagttgc 391320 ttaaataatg cagaatcttt ctccaacact ataaacatat ctgacattaa aaaaaaaaaa 391380 caaaccagta acaaaaaaaa aaaaaacaca caaaatctct gcaattttta atttctgaga 391440 tgtcaaataa ctttttccac cgggctacag ctttatgaat tctcgaattt agacaattct 391500 aaaactaaaa tttagacatt ctaaaactaa aatacatttt aaagtaaaaa tcacatttcc 391560 tagttgtctg tgtcagacaa ctttactagt atactatagt attattaact accttaattt 391620 ttgttgacat taaattttac ttgaagatga taaaaaagta gcagcaatga cagggatagc 391680 taatactaga aatacaataa agctctgcga taatgcacct gagacaaatg taaattttgg 391740 tgaaatgtga ctgacgactg ctttctgtct tctggccact cttatattct taaacagata 391800 cactaaaatt atcttgtgga ggaaagaaaa ggaacaaatg gcaaccccat ctggaaaacc 391860 aggaagttag gatgagtacc tgagtttcca gtatttccct gctcaatctc cctggacttg 391920 atgttacagg caccactaat ccccagattt ttggaatagc tgctgttttc cagaagttcc 391980 aagacccaga gttgtctcta tgaattttta agtgggaaga aactaccaca gccaggcagt 392040 gccgtccaca cagggatatt ctaagtggcc cagcaggact caactcttac tggcaacagg 392100 cactgatctg ccatggtcac ttcatcaagt ccacaataat gcaactctga attttacacg 392160 atggaatttt ttggacacta cctataattt tatggtatgg ttttactgta ccattactcc 392220 cagttcaaga ctgcacatcc acacttatta ttgggtatct ccacatttct cttgttctgg 392280 tctttgtcca acactctatt ctcttctgaa tgaaagaaac tttggattta gttttcaaga 392340 tttagaaaac ccattctttt tcaaagatag catgaccatt atataataca accgatactt 392400 tgtagaacac atctataaac ttgcacagga acaacaaaag tataatactt atataagatc 392460 agaaatgtcc atgtgttcct atgctatatg gtatcatttt tttcagtcac ttttaaaatg 392520 aattcactga actgtatcat gatatcccca ttattaggtt tttaatctag cagcccaact 392580 tacccggaca agtgcatcat ctatgatatg gtcacgtcta actttgagtc tcaaatatgg 392640 attcaactgc tgtccttgaa ctaagctgta gagaacagtg attcttcgtt cactgtacat 392700 gcgaattcta ttgtcataat ataatcccaa attctttgtg acagcattca atataaaggg 392760 acatgtcata aaagagaatt tgttctctgt ttctactttg aaaaaagtat aatctttatc 392820 catttctaga acctcattca gtggttcatt aataaactct tcaaaaggga taagtggttt 392880 tcgacaatcc agggttttaa caccaagttc agtttccagg gggtccactc gaggaccttt 392940 cttgtttctt ctttcttctc ccaaaagttc ctgaagtgtc agctcgctgg actcagggat 393000 gggctcttca tcatcttctt cattgtgatt tgtgtccact tcccctccca ctacatttgc 393060 atagtaaacc attttcaagc acttcgaagc agcaacaatg gcatcatcat cattcactag 393120 atttcgactg ttaaattcat tgcttatgac tttataagta ataagttgct gaaatgtctc 393180 catcattctc cgaatctggt ctgcattgta tttagaccac agtctgatca gttttccttg 393240 ggctgcaagg ggtagcttgc tcatcgcttt gcaaaataat ggcaaagcca tttccagata 393300 ttcaggactg tggagatttc tattctccat tacgataatg aacaaattca gataattagg 393360 atctcgagag tatacattgt gatacgtcaa gtcacattcc acgttaggtg acaaatatac 393420 aagtgcattg agaaaggcag tttcaatttt ttcattagag agcaatctgg tgtagaccct 393480 tctaatggca tcaatatcca cagacacatc atcagggcct aatttttgca aattgttgtc 393540 tccctgtgag ctatcaccta tccttgagga agatgcttct gagtcttctt ccatagcagc 393600 agcagaacat gcagcttttt ccttttcatc ttcatctttg tcttcatctt ttgcttgaag 393660 agatttcagt tcttccttgg tgtgttgttt aactttccgg aagctctgta ccaatgcctc 393720 agcactagaa aaaactcttc caataacacg gattaaaggg gaataatcct ctctttctct 393780 acataattca agaatttcat ataccttctc ttctgttaag taagtcacat ctagaaaatc 393840 agaggaaaaa agagaacatt tattttcata atatgtatgt ttactctgtt gcaaaaagtt 393900 ctaaaagtaa aacagccaaa cattctaggc tcaatatcat ttatgatata caactcttaa 393960 agtatctaat acttagattc agcaaacaaa atttaatgct tacctatttt tttcaatgaa 394020 ctacctacct ataccaatga cctcacccat gcttttacat tctttcaaca atgtataact 394080 cttaataaga tcatgagttt aaactttctt tataatcaag atatctatta atgtatagct 394140 ttaattataa atatgaacca atatgtcatg tactgattaa tcataataca gctcttaaaa 394200 cctcactgta gaacacacag aaatactact aatctgtgag ttttcttgtt tcagtactct 394260 gttctccaaa gactaagaag gcaaggtctt aaaaaaaggc tccttcagca tctatgtatg 394320 tattaaaatc aaactggttc attttgggtc ttcctagttt gttccagggt agtcattctg 394380 tgagtgattg agaagaatat accatttctc atcggctctt aagtagaaac tgctttccac 394440 agccaggaat caggttagac taaatctcat agagtgacag aaaatagttt ttgagcaatg 394500 aaaacaaaca gtgcaaagaa gtaaacttat gagctggcaa gcagtgcaga gactatgtag 394560 tcatcaaaat ctatttcctc ttttcctggg cacagagttg gaccacattt cccaactttt 394620 tgagataagt gttattttca ggccaaggct ttctcccttc tggctaatag gatgaaagat 394680 atttcatttc acaggtaaaa acaaatgata tattttgtgt actgaccaac ataatactga 394740 gaatagtctt aattctccct tttatcaata aagtgacata cttgtcatca tcagattaac 394800 tacttgagag gttaatttta gaggcacaca gacaatccta cctccattgc gccaaatata 394860 cccttataca tgtagtgtac aacatgtaga atttttaatg actcccacct ctgctataat 394920 atatgtttca caatgaaaga caatataaaa tgtaagtgat cattgaatgg tctccaaaaa 394980 ttgaagcaca aaaataccaa attttatcat actaaggatc tgatctgtgg cccagctaca 395040 agagtaccaa cacttacagt ttcttttatg ggccttaact ctttaagaac taattctcag 395100 gtttgttcta ttaagaatat ataagcatct tttgctaaac atcagtaacc tcttccccaa 395160 aagcataaaa ccactggaaa cctatttctc attattttca ttgaaaattt ttaaaatacc 395220 ttcttacaag acaatgcaaa actcctaatt tcctaaaatg taacataaca gaaaatacta 395280 ctatcctatt aggacatgaa acactttgct tcctgagcaa gtcataaggt taacaaagac 395340 ttgctttgca tgcagtaata tggcctgtcc tagggatcac cattctagac tcacatgtcc 395400 tttgttgata tgtcatgctt tcggaacatc ttcaagtgat tctgacagtc tactaatcct 395460 atatagaatg tacctatact ttttccaagg agtgtttttt gttgttgttt tttgacatgg 395520 agtctcactc tgttgccagg ttggaatgca gtggcaccat ttcggctcac tgcaacttct 395580 gcctcccggg ttcaaacgat tctcctacct cagcctccca agtagctggg actacagatg 395640 cacgccacca caactggcta atttttttgt atttttagta gagagggggt ttcaccacgt 395700 tggccaggtt ggtctcgatc tcttgacgtc gtgattcgcc cgcctcagcc tcccaaagtg 395760 ctgggattac aggcgtgagc cactgtgcct ggcctgtagt gtttaatatg ttaaactgaa 395820 tttttcaggt atatagataa aaattagtca aaaaacactg taattagata tgaacattca 395880 aaaagtttgg tttattgata caggtgttct actgagaaag acatttttat aagatttctt 395940 gtgataaatg tgtccctgaa aatactcaat cttttaaatt ttgcacttaa aaacctccta 396000 cgcaaaaaca gtttggtgca gactacttaa tacttatgca actttgtaat tagtgttaac 396060 aaacataatt aataatcaaa ataagagtac tagtgtacag aaagcatctc taatttccaa 396120 tatacaatag taactataga acaatgcaaa aacaaaaaca aaaaaaccag taacgaacag 396180 ggaacagtaa cagtagcata ttagaaaaca gggataagga aaggtcacaa ctgctataat 396240 gcagacttga gcaaaaagag gagggggcat aaagactgga taaagccaca caataagcac 396300 ctctaagatg gagcacgtgg ccaaaagagc agatgagcac attcctcatg taccacatcc 396360 cccgcagctg gctgcattcc actgtgccag cactctacat tcagttactg gtactctctg 396420 gtgcacactt actggagaac tgtgtacaat aaagtcaatg cagcttccac attatactga 396480 cacactatat atacagacaa catttaccta ttttcccata gtgtgtgaac taattcatga 396540 aacagaatta tacactctga agcaacaaag ttgtgtaaag tgacgaaaat aattttattg 396600 tggaaacaga gtagaggtta taacacaatg ccacttcact aattctttca aacttgattc 396660 aaatgatgtt agtgaaagtt ttagaggcaa atgcctctaa aattctctga cttgtatgtc 396720 ataaaaaaaa agctttctct cttaaaatac aattgcctct gggtgtgtgt aggggtgaga 396780 gtggaggggc gctaagccct ggtagtcatt caaaaatttg attactttgt tactaattac 396840 cttcactgaa gaaaataact tggagtttta gtattagcga caaggtaatc gaattctgaa 396900 ttttggacgt aggaccattt agaaaacaaa agacctgagt gaagactgtc attggtaggt 396960 catgatcctt ggcagcatga ctgtaccaaa tgtccggaag gagagtgaga agcatatatc 397020 tgaaggaaac gtagaattct cacataacta tcacaaaatt ttgtcttgcc ttcaaaaatg 397080 gaaaaaaccc actgtttcct ctttctgctt ctttcatcac atcatcctga ggttccagaa 397140 ctcatgccag atacttagtc cagttattct ataacttaaa tagatgttgt ggcctagttt 397200 tggagattca ctaccactta atacattttt cctaagaatt ttaaaaagtt caaatcaatc 397260 tattaacaaa tgaacttttg gcatatgatc tgcttctaat tagcaatgat tagacctgta 397320 aaatgtagtt attattcctg tccgttacca caataaaaaa ttggttctac gatatcaaaa 397380 tgtctttatg tcacagaaga aaaaacaaat aaaaactaat acatttaaat ctcccacatg 397440 gttttcaggc aacaattctc aattgaaaat aaaacatctt acctttaaaa tcaattctag 397500 cgcctttctt gttcattttt atctcagagc aggagttgtt gggggcacct ttcgagttct 397560 caaggtaagc tgagcttgct cctttcttgg agggatgagg atcacagagt tttgcattaa 397620 tcttataaag ctcgagggct ttaatagctg ctgcattatt atccatacga agaaaagttg 397680 gacaggaagc acaaaactca ttcgtgcagg cttcatttcc acagccctca gttaactggt 397740 ggtagtagcg ttctattaga tgctttgcag ctgctcgctt cctgtaccaa acattcaaac 397800 aataagcaca gtgattagta cagctctcaa gtacaaagct caacatatca tcaaggcaaa 397860 agttagtcaa gcactgaagt gattaacctg tgtatgaaga tgagaagtag aaaatggaga 397920 tgcactattt accacaactc ctgactagtg aaatagttaa taaatatttt ctaggatatt 397980 atgataaaga atgtcaatgc ttactgactg tattaacaga gtatacattc ctttggttta 398040 aaagggggga ggggggcttg tctgatggta tatgtgctta agttgtttag tacaacagct 398100 gaaaaatcac aaggtttaca gctaagagtt gtaggattct atcattttaa aaattagcat 398160 taggaaaatg agtctattta aagcatcaat ccggttttct tttacataat cagtatttca 398220 tttttaacag cttgtaaaca tttgacttat agttaacaca gaatatctat ctggaataaa 398280 aactattttt cccaattatc aacaacatgg gagacttaaa aataaatttg taagtggaat 398340 atccaaagat agtgttacac tgaaagaaag cggctgcagc ctgagtgagg cagatcatga 398400 ctgtaatcaa tcccataact gtgggaggct gaggcaggcc gactacttga gcccaggagg 398460 tcaacaccag cctgggcaac atagtgaggc tactctctac aaactttttt aaaaaaaatt 398520 agccaagtgt ggtggcatgc acctgtagtc ccagctactt gggaggctga ggatcacttg 398580 agcctgagag tcaaggctgc cataagctga aattgcacca ctgcactcca gcctgggcaa 398640 cagagctaga ctttgtctca aaaacaaaca aacaaacaaa aaccaaaaag aaaaagaaaa 398700 agaggctcca aagtgtagaa tcttaaatct aaaacttgtc actaaacctc ctcattagtt 398760 ccacgtcaca agatggaata ttttaagttc catcacgtga aatcttatat tccttttact 398820 ctgtcaactt aaagtacaca gattaatgtc ctattatggc tgtttcagga gagctaccaa 398880 aactgaggga ggaattatgt gaccatgtaa gaagttagat gacattatat tcaacactaa 398940 agagtctatg cttctactaa ctgataaaat taccataatt tcagtagaat aaactactgg 399000 atccaaagaa acataagtca tagccattcc ttttggtccc aaattcacaa gcatggaaat 399060 aacaactaca aagaatcaaa attataagaa aaatagttca gctgattttc aaaacattca 399120 cagaattatc taacatgtag gactagatga ccaatgccag agtttacatc ttgctaatca 399180 tgagaaactc aacaattaac aaggcagcaa gtaagtgaag aaacacacga gatccaattt 399240 tgtctcaaca gaagaacttt cactctctgt ccaggtaggt gacaaaaagt gataattcac 399300 acacattcaa ttcattctgg tgcttatttt tcaaatgttc catgcaaatt taccactcac 399360 tgcatgcaaa cagagaaaaa agaaaaccca caaagcacat gtaaaaattg cataaacatg 399420 acttaaagac attttgctat ctatgaagct ataaacccca cctgaaaatt aaaaactgtt 399480 atcacagatt tagcactatg caaaatatga aagtgaaaac atgtaaaaat aaaatggaaa 399540 tgcagaatct agaaaattta aaatatatat tgctaccctt cagtaaagaa agggagataa 399600 tgtcatgttc tcccaaacta cagtgacttc cctggtgaaa atgtaagtag gtatttcctt 399660 tctggaggaa aacagtgaac atgtatcgaa agtcttaaaa acacgaatac cgtgtgaatg 399720 agatcctact tgtggaaaat aatttgacaa ttttacaaaa atgcattgtt tctatatctg 399780 aaaaaaacat gtctaataaa agattactta aatgaactga taataggtca cacaataaaa 399840 taaaaactat caagatttga attcgacaaa gaactgccta gtcttcctga tatatcacta 399900 actgacaaaa gtcagttaaa aagtagcagg tgtaggatga acccattgtt atttcaaagc 399960 attaatagca ttttctctgg atgatgtgat taagtgagtt ttaaaacttc ttccatcttt 400020 tgatttctta tttattcttt ccatagtaag gatgctactt gcatattaaa aattaataac 400080 tataagggga aaacaatagc agttataaaa cttcatatac atgatttgaa tggccccgag 400140 atttactaaa ttgtctctga tttttaaaaa aattacaaaa gtcaaaatac caaaatagat 400200 atttttaatg tgagctttta tactaaaata acctccccaa aacttgtcag atacatagta 400260 cttctttata tactacatag gaggagagtg atcagcacaa acagaacgag actgaaaaat 400320 cagaagatct gcattaagtg tcatccttct gtccctaagc agctgtagga tcctagggaa 400380 acaattgtct gggcctcagt tttcccagct ttatgagtcc cttcagttct aattttaaag 400440 ttattttatg taatagggag gtgagcaaga aactagtatt tgctggatgc ctgataactt 400500 attacacaca ctgcggggca ctttgacatg ggttatctca tttgaatacc atgacattga 400560 ggattatctt cagtccacag ccaaagagag aaatagaact ggagtcaaat cacgaaacca 400620 agatctcaaa gaaagtacag aaccaagaca agaataggag tccaggagtc tttcagcttc 400680 agagtctaag tcattttgac tatattgttt tgcagaaggt gattcatttc aaaataatta 400740 ttttttaaca tgagtaatac tgaagaattc tatggaaaaa aatctcataa ctaatgtgca 400800 actgggaaaa aaatctgaag aatcataacg tgaacctcac atttatgcat ctatctggta 400860 ccacaaaggc agaccaagtt tcttgaggaa atggaaccac tatattctgc aaagttaatt 400920 tctctctaat ttgttgagga cctatgtgct atgcatttta tagacattcc cactttagag 400980 gggaataaac cttaacagtt aagagctcgc attctgaggc cagatgccca agttcacata 401040 atggctctac ctcttaatta actatgtgac cctgaatgaa ttacttgatc tttctggacg 401100 taagtttcct cgtaatttaa atggtagtat ctacgagcat tatcatggtg agagtattat 401160 tcttcttcac attaccaatt gtgagaaaat taaatgtgtt aatatatata aagtgcttag 401220 aacattgcct ggcacatact aagcactatg aaagtgttag ctactactat tattgttgta 401280 attgttacta tcaccctcac aagtgtatga gttagcacta taaaccttca ttctgctgat 401340 gctcagagaa attacataag tcatacatct aataagagat ttgaactcag ctactaaact 401400 tgagctttta ataactatta agaggaggat ctgaaagtag ccctctatat ttgatctgcc 401460 tttctgtgcc aagtttaaca aatagcagct acactgatga gacaggacta aaggaagcca 401520 tgccagaacc tccaagttaa tggtggaatc aactatatta agcattcttc ttttttcctc 401580 actccaatga caccttaatt tatctgacct catctgcatc actatctaat ttaggatatg 401640 taaaaggcat acaaaattta gagcacataa aagggcctct acgttggaaa agtatacact 401700 aataacgact ttttggtata gttcctgcgc aagggaaatc cttgtaccat atgggtcacc 401760 aaatcatagc tcgtaagtca aatcgagtcc accacctgtt tatgtctctc aagcttagaa 401820 tattttacat ttttaaatgg ctggaaaaag tttgaaaaat aataatagtt tgtaacgtga 401880 aaattataag aaattcaagt tccagtatcc atcaagtgta ctggaacata cccaagttca 401940 ttgatttata aatatactat atatgataat gctttggctc tgtgtcccca cccaaatctc 402000 atcttgaatt gtactcccat aattctcatg tgttgtagga gtgaccccct gggagataat 402060 ctgaatcatg ggggcagttt cccacatgct gttcttgtgg tagtaagtct cacgagatct 402120 gatggtttta tcaggggttt ccgcttttgc atccttctca ttttctcttg tcactgccat 402180 gcaagaagtg tctttcacct ttcgccatga ttctgaagcc ttcccagcca tgtggaagtg 402240 taagtccaat taaacttctt ttttttttcc cagtctcagg tacgtcttta tcagcagcgt 402300 gaaaaaggac taatacaata tactatatag tttatggctg tttttcatac tacaatggca 402360 gagttgagta ctttaggcct gcaaaaccta aaacaaatac cacctgccct ttacagaaaa 402420 tgtttgccaa cccttagttt aggatctatt atttatctct gccctccagt gaccctgcca 402480 tctaatcatt tggcctctta actctctctt taccctgagc aaatccgtaa aataaaaggt 402540 atacctttcc ccaagtacta ttaaagaaaa gaagaggaga ggggaaaagg gaaaaagggg 402600 aaaagaaagt gaggaaaggg agaggatgca aaagaaaaag aaggaaagaa aggaatttcc 402660 ctgatgagat cccttagtaa taccttatca gctgttcata atcaaaattc ctagaagagg 402720 aacaacagct tacttgctat aatttcttca cattccattg acttttctta ttactcaaaa 402780 aacaaagtat gttataatgt gttgattttt aaaataaaac aaacttttct tatttagtca 402840 gcaatgaagg tcaagtgaga ccttctagta aaagtcctct aaagtcagac acatgaaaat 402900 acttatccat ttaaaacaga caatactttc caattattta tttctatgat tgaattaatg 402960 ggacagtgct acaaacagaa gtcctatgga ataagtcata cttggaagat cagagtttac 403020 tctagacaac ttgacagcaa tcagtttaaa aatggtttca cctagaggga tgtgtactaa 403080 tgttagcaat taactttgaa aggcataaaa attaagatgg attgatggat acaaggatgg 403140 ttatacgata aagcaatgta agtattaatg gcagaatcta ggtggcaggc atatgtgtgt 403200 cagctgtaaa atttgtgttc aatgtttttt tagttcccac atatcagtga gaacatgtga 403260 tatctgtctt tccgtgtctg gcttagttca ctaaaaaaat gaatttacaa gacaactgga 403320 atataagcaa tgaatacaag cactaagaag atgaagccat agaaacagct gccagaaagt 403380 gaagatgtga cagtgaacgc caaacaagta agattagaat tacaattaga atcagaaatg 403440 acaaaaaaga aacatgaact gtgagatgca atataaaaac taatggtgaa caaagcaaag 403500 aataaaaaat aaaaacggaa agattaaaag gaaaatgtga ctgtaagtag agtgaccttt 403560 atattataca gaaggtaaag cagaatgaac atgtgaggaa tctaaaaaac agatataaaa 403620 tagaaacaac tgaaggctta tataattagt ctataaagct aggaaccact gcttagtaat 403680 ttctcgtaag tggagtctct ttgttctgag acgttgcaaa actccattcc atctcaaagt 403740 tatttttaat gttaaaattt gtaagagtga gcaacggtat cctaaatagt tctaggcctt 403800 gtagaaatag actgtaagag acatctgtga cacaactata ttcagtatga tgtagggtct 403860 gttacaatgg gatgaagtga atttagatta tttcaagact aaacctacaa ttgtgaactc 403920 attagtacca tgaaccgaac aaaaacctat taaatataga acaagacgat tttcatgaaa 403980 aaataaatat gaacaaatca gtattttcag ttgtttgaaa tataggttaa ccttcaatta 404040 ctgttttatg gccgggtgca gtggctcacg ccacgcctct aatcccagca ctttgggagg 404100 ccgaggcagg cggatcatga ggtcaggaga tcgagaccat cctggctaac atggtgaaac 404160 tacgtcccta ctaaaaatac aaaaaaaaat tagctgggcg ccgtggtggg cgcctatagt 404220 cccagctact tgggaggctg atgcagaaga atggcatgaa cccgggaggc ggagcttgca 404280 gtgagccgag acagagccac tgcactgtgg cctgggcaaa agagcgagac tctgtctcaa 404340 aaaaaaaaaa gaaaagaaaa gaactgtttt tttcattttt atagtctcaa tatccagaat 404400 gcgtgatata tgataaaaaa aaaagtaaaa ttgtagaact aaatatttac ataattcatc 404460 tgtaaaatga aaatctgttt tacagtgtca tatttcacag ttagaaagga agaaaaacct 404520 taaatcaaca aattaacttt acatcttatg gaattaggaa atgaagaaca aatgagactc 404580 aaacttacca aaaaataaaa aaaataaaaa taaattacag ctaaaataaa atagagaaaa 404640 atagaaaatt tttgcaatag aaaaaaaatc aacaaaatta ggagtagctg ttttattgaa 404700 aagatcaaca aaactggcaa attcttagat taagaaatga agagaataga cacaaacagc 404760 aacaactgga aattagaaag gcgatacaac aactgctgcc acagaaataa ataggacctt 404820 aaaagactaa tatgaacaac tatgacccaa aaaaatttga taacctttga gaacggatag 404880 acacatcaaa cccaccaaga ctgagccaca aatacataca acttctgaat ggacctataa 404940 ctattagaga ttgaatcagt aactgtccaa caacgccagg gcttcactga aaactctacc 405000 aaacatttaa aaactaacaa cccttctcaa actctttgaa aaaactagag gacagaacac 405060 tttcaaaatc attttatgag gtaagcatta cttagatatc gaaatcagac aaatttacaa 405120 gaaaaaagaa tccctaataa atactgatgc aaaaaaaatc aacaaaatac caagaaacag 405180 aattcaacaa tgcattaaaa agattatatt tcataaattc tcaactggaa tttattcata 405240 aaatccaagg atggttcaac atacaaaaaa atcactttaa tacactgcat tcttaggaca 405300 aaaaccaata atctcaactg actcagaaga agcatttgac aaaaatcaac acccttttag 405360 gatttaaaaa aaggccagac agggtggctc atgcctgtaa tcccagcact ttagaagggc 405420 aaggtgggtg gatcacctga ggtcaggagt gtgagaccag cctggccaac acagtgaaac 405480 cctgtctcta ctaaaaatac aaaaactaat cgggcatggt ggtgggcgcc tgtaattcca 405540 gctactcggg aggctgaggc aggacaatca cttgagaacc cgggaggcgg agctggcagt 405600 gaggtgagat agcatcattg cactccagcc tgggtgacaa gagcaagatt ctgtctcaaa 405660 aaaacaaaaa caaaaacgct caattcgcta gaaagatatg gaaattactt caacataatg 405720 aaggccatat atagaaagac cacagctaat gttattcaat gatgaaaaac tgaaagtttt 405780 ccctctaaga tcacaaatgg aacaagaatg cacacattca ccacttctat tcaacatact 405840 gttagacatc ctgccagagt tagcaactgg gcaagaaaaa gaaatgaaag gtattaaatg 405900 agaaaagtaa gaagtaaaat tacttctgtt agcaaatgac atgatctttt atgttgaaaa 405960 ctctagccta ccaaaaagaa aaaaaaccgt tagaataaag gaattcagta aagttacagg 406020 atataaaaac caatattaag aaaagagttg catttctaaa tactaaaaat gaagaatcca 406080 aaaaggaaat taatttttta aacccattta aaatgaaatc aaagagtaaa aaatacttag 406140 ggaatatttt caccaagcaa atgaaagaca tgtacattga aaattaaaca acataggccg 406200 gacgtggtgg ctcacgcctg taaccccagc agtttgggag gccaaggtgg gctgatcacg 406260 aggtcaagag attgagacca tcctggccaa catggtgaaa ccctgtctct actaaaaata 406320 caaaataaat tagctgggct tggtggcgcg cgcctgtaat cccagccact cgggaggctg 406380 aggcaggagt tgtcacttga atttgggagg cagaggtgca gtgagccaag atcacgccac 406440 tctactccag cctggtgaca gagtgagact ctgtctcaaa aaaaaaaaaa aaagaaaaag 406500 aaaattatac aacaatgctg aaagaaatta aagacaatac aaataaatgg aaagacatcc 406560 aagtttatga attggaagat ttagtactgt taagatggca atactaccca aagcaatctg 406620 caaattcaaa gcaatcccta tcaaaatccc aatggcattt tctacagaaa cagaaaaaaa 406680 aaatcttaaa attaatacag aatcttgaag gaccctgaat agccgtaaca atctggacaa 406740 aaaacaaagc tagaggcctc acattccctg atttctaaag atattgcaaa gctatagtaa 406800 tcaaaacact atggtgctgg cataaagaca gatatacaga ccaagtgagc agaagagaga 406860 acacagaaat agggaaaaga ggttcttcaa caaactgtat tgggaaatct ggaatctaac 406920 atgcaaaaga atgaagttgg agccttatct cacaccatat acaaagatga actcaagctg 406980 gattacagac ctaaacttaa aacatcgaat tataaaacta ctacaagaaa acatggagaa 407040 aaagcttcat gacattggac ttggcaatga tttcttgaat agatcaccaa aagcacaagc 407100 aaccaaagca aaaatagaca aactggggat acataaactc aaaaatttct acaaagcaaa 407160 cagtaaatgg agtaaaatgg caacctacaa aacaggagaa aatatttcta taccatgtat 407220 ctgttatttg gttaatatcc agaatatata aataactcct acaattcaac aacaaaaaat 407280 ctagttaaaa agtggacaaa ggacttgaat agtcattttt ccaaagaata tatacaaatg 407340 ggcaataagc ccatgaaaag attctcacca tcactgatca gtagggagaa atgtcaatta 407400 aaactgcaat gatacatcat ctgaaaccat taggatggcc accattaaaa aaacagaaaa 407460 taagtattgg tgaagatatg gagaaactgg aacccttatg caccactggt gaaaatgtaa 407520 aatggtgcca ggcactgtgg aaaacaacat gaaggtccct caaaaaattt gaaatagaat 407580 tacctccagt tccacatatg aagagcttgg aagtcaccac tccatcctaa caacaagtaa 407640 aaaatgacaa acttaaaaat aaacaaatct gagataggat aagtgaggtc acagggcaaa 407700 tgactgcctg tgagagcaga gaacaggtga acacatagca tcaccattta tctgagatga 407760 aaaacacaag cagaaacctc cacggggtag gaaatcctga agtgtaatag acaaattgat 407820 gaaggctcag tgtggacaac tctgaaagct aaaaactcca gagttaccca attatagggg 407880 gagccctaca attttctaag ttttacatcc aggcaattga ccagcttctc acagtaaata 407940 taggagaaaa atcctcaacc ctcagcaggg gaggcaaaga gaaatgattt tcaagtacac 408000 tagactattc cagtcttaac aaggtttgtc ctcaggagaa actagttaac cagagcctaa 408060 cctgctgggg ttgtagcaaa gccaaaatga tgtgggggaa gagaaataac ccaacttcag 408120 gccattatag ctatcttgtt ctaactaagg gaatgaggga ggggtgggat tgagaaacac 408180 ttgtgaagtt cacagtccag aggcataagc tcactaaaaa gactgaccta atcataagac 408240 tacagaactc ttctcctctc cctacacctt acaaccacat tactaaatgc tcatttacaa 408300 cagttccttt tacctagtac atcatgtcca agctatcaag aaaaaaatta cagggcataa 408360 taaaaggtaa aaaacaagca ccaggaccag atacagcagg gatttggaat tatcaaactt 408420 ggaatctaaa acaactatga ttaatatgct aagggcccta acgaactgag taaacaacat 408480 gttaaaaaag tagagatgaa aatcctaaga accaaaagga agtgctagag ataaaacaca 408540 aacaaaaaca aaaaacagaa cactgtaaga gaaatgaaga atgcctttga tgggcttatt 408600 agtaggctgg gcatggatga agaatctctg agcttgaaaa tatgccaaaa aactacatct 408660 gggcataaaa cgttgtaatt acagaaattc aaggataaga aaaaaatccg aagtaagcca 408720 gagggaaaaa atcaccttac ctgtagagga aaaaaagaaa aaaaagaaaa aatacatgtg 408780 acttccaaca agaaaaagag tgaaatattc atagtgttga gagaaaaaaa aaccataaac 408840 ctagcactct accttgtgag attattattc aaaagttaaa aagaaacact ttctcagaca 408900 aaaattaagg aaatttgttg tcagtacacc tgccttgcaa taagtgttgg gaagttcaga 408960 aactgaaatc tacatatata gagcatcaaa agaaggaaac actgaaagta aaataaaacc 409020 ttttattttt cttatactta attgatctaa caaataagaa tttgttcaaa ataatgtcaa 409080 caattgtgct tatgcataca aatgctccta aacttactta ttgggttgtg tcccaatacc 409140 attataaatt gaaaatatca tgaaaacaca acttatccaa atttgtggga tacagtgaaa 409200 gcagcgctta gaaagaaaca tacaacactg atgcatttat tagaaaagaa ttatctaggc 409260 cgggcgctgt ggctcacgcc tgtaatccca gcactttggg aggctgaggc gggtggatca 409320 catggtcagg agatcaagac catcctggct aacacagtga aaccccgtct ctactaaaaa 409380 tacaaaaaaa ttagccacac gtggtggcag gcgcctgtag tcccagctac ttgggaggct 409440 gaggcaagag aatggcgtga acccgggagg cggagcttgc ggtgagccga gatcgagcca 409500 ctgcactcca gcctgggcga caaagcgaga ctccatctca aaaaaaaaag aaaagaaaag 409560 aatgatctaa aaatcaatta tctgagctac caacttatga aactagaaaa agcaaattaa 409620 atccaaatag aagtaataaa aattagagca gaaatcaatg aaattgaaaa caagatatca 409680 atagagaaaa atcaaagaaa tcaactagtt ctctgaaaag atcaataaaa tcaataagcc 409740 tctagccagg ctaagaaaaa gagacaaagg acaaaataac taatatcaga atgaaaagag 409800 tggacatcat tacagatctc atggacatta aaaggataat caagggatat tatgaacaac 409860 tttacggcca cgaatttggt aacctagatg aaatgaatca attccttaaa agacacaatc 409920 tattagaact ctaagaagaa ataatcttga ttaaaaagca tatattaaag aaattaaatc 409980 cataattaat aatgttctaa aagagaaggc atcaggccca gatggattct ctgatgaatt 410040 ctactaaaca tttaaggaag aaaccacacc agttctctac aatctccttc agaagacaga 410100 agcaaaggag atgctcctat ctcattgtat gaagtcagca ttactctaat acccaaacca 410160 gacaaagaca ttatcagaaa agaaaactac agacccatat ttgtcatgaa caaagatgca 410220 aaaatctttg tattagcaaa gtattagcaa actaaatttt actacaatgt ataaaaagaa 410280 gtatacacca gcacaaagta ggatttatcc caggtatgca agactggttc aatattggaa 410340 aatcaattaa tgcaattcac catatcaaca gactaaagaa gaaaaatcac atgaccatac 410400 catagatgga gagaagtatg tgacaaaatt taacacccac tcatgataga aactagtaaa 410460 ctaggaatag agggaacacc ttcaacttga taaagaacgt ttacaaaaaa catacagcta 410520 acaccatcct taatgatgag aaactagaaa ctttcttact aagatcagga acaagaaaag 410580 aatatcccca cctcaccact ccatactgga agtcctagct aagacaagaa aaggaaataa 410640 agggtatact aacggggaac aaaaaaatac aactgccttt gtttgcagat gaaatgacta 410700 tatgtgtaga acatagacag gaattgaaaa aaagaaaaag aaaaacaaca aaaacctcct 410760 agaactaata agtgattata gcaaagctgc aggatacaag gttcatataa aaaagttaat 410820 agctttcctg taaaccagca atgcataagt tgaatttgaa attaaaaaca caataccatt 410880 ttacattagc gtgtcccaaa atgaaatatt taagtacaga tctaacaaaa ttagtacaag 410940 atatatgagg aaaaatgttt tagaactctg atgaaagaaa tcaaataact aaataatgaa 411000 gagctattcc atgacccgtg agagacaact caatattgac agaaaaagtc agatggacac 411060 tactgatttc aagatttact gtaaagctac agtagtcaag atggtgtggt actgacaaaa 411120 gaactgacaa aacagaccaa cgaaacagaa tagagagccc agaaatggac ccacatagtc 411180 aaaggagcaa tggcagtatt tgacaaagag gcaaaggcaa tacaatgaag aaaatagtct 411240 ttttcaataa acagtggtaa taactgaaca tccacatgca aaaaaaaaaa gagtctagac 411300 acaggtctta cacccttcac aaaaataaac tcaaaataaa ccagagaatt aaatgtaaaa 411360 ctcaaaacta taaaactcct agaggataac ataagaaaaa atctagatct tgggtttggt 411420 gatgactttt agatacggca ccaaaggtac caaccatgaa gaaaagaact gataagccag 411480 acttcattaa aattgtctac ttgtttctta aaaattgttg tcttttgcaa aagacaatgt 411540 caagagtatg aaaagacaag ccacagatag ggaggaaata tttacataag acacatctga 411600 taaagaacta ttaactaaaa tgtgtaagga ggctgggtgt ggtggctcac atcccagcac 411660 tttgggaggc caaggtgggt ggatcacctg aggtcaggag gtcgagacca gcctggctaa 411720 catagtgaaa ccccgtgtct actaaaaata caaaaattag ccaggtgtgg tggtgcacgg 411780 gtataatccc agctactcgg gaggctgacg caggagaatc acttgaaccc aggtggcaga 411840 ggttgcaggg agccaagact gtgccactgt actgcaacct gggtgacaga gcgaggctct 411900 gtctcaacag acagacagac agacagacaa gacagacaga gacagtgtaa ggaactctta 411960 aaattccaca agaaaacaaa caacccaatt aaaaaattgg ccaacaacct taacagacac 412020 ctcaccaaag atatacagat ggcaattcag catatgaaaa gatgtcccac acatcatatg 412080 gcatcagaga aacacaaatt aaaattataa gatacctcta cacacctatc agaatggaca 412140 aaattcagaa cactgataac accaaatact ggtgaagatg tagagcaaaa gaaacactca 412200 ctcattgctg gtgaaaaatg taaaaggata gcgtcatatt agaagacagt ttggatgttt 412260 cctacaaaac taaacacttt taccataaga tccagcaatt gcactcccta gtatttacag 412320 aaagtcgctg aaaacctaag tccacacaaa aacctgcaca ccgatatcta cagcagtttt 412380 attcataatt agcaaaatgt ggaagcaacc acaatgtcct tcattaggtg aatattcatt 412440 cacaaactgt gatatgtcca gaaaatggaa aaagagaggt actaacaacc tatgaaaaga 412500 catggaagaa actttaatgc atattagtaa gtaaaaatag tcaagctgaa agggctatat 412560 actgtatgat tacaagtata taatatgctg gaaaaggcaa agttagagac acagtaaaag 412620 gatcggtgat tgccaaggag tgggagggaa ggaaagataa ataggcagaa cacagaggat 412680 tttggggcag tgaaaacatt ctgtatgata taatggtaga tacatgtcat tgtactttgt 412740 tcaaagccac agaacgtaca gcactaagaa tgatccctaa tataaactac ggactttggg 412800 taattatgat gtatcaatat aggttcatca gaaagacatg taccactctg gtgggagatg 412860 cacactggct atgagagaat ccatacatgt gtgtggaagg aggtacaggg gaaatctctg 412920 taccttcctc tcaattctgt gaacctagaa ctcctgtaaa aaaaaaaaaa atctaaaaaa 412980 aaatagaata catatgatcc agtaatccta cacctgggta tacttccaaa tatattaaaa 413040 acaggttctc aaaaaaatat ttgtataccc atgtttattt caacattaca atattcaaga 413100 agtggaagga acctaaacat ccatcaacaa atggttaaag aaaatgtggt atacatatat 413160 aacaaaatgt tattcagcct aaaagaaaag aaagaaattc tgtaatatgc tacaacacaa 413220 atgaaccttg aggacattgc tatgtgaaat aggccagtca acaaaagaca aatacttaat 413280 gattccactg acatgaagta gccaaaacag tcaaatttta gaggcaaaaa gtagaatggc 413340 atttgccaag gaataggaag aagggggaaa agaagagttg ttcaatgaat gtagagtttc 413400 tgttttacaa gatgaaaaag ttctagagat ctgctgcaca acaatgtgca cagttaccac 413460 aattgtaccg tacacttcaa atcattaata tggtaaaatg tgttgttttt gacaattttt 413520 aaaactctac cccattgttt tctttacctc ttatataaac tgataaaaac ctgttttatc 413580 ttaatcaatt attgtatgac tactgctccc cagagaaaaa agtgcatgtg aaatactact 413640 acttatccat ctcctggctc tgagcagtac atgtcaggaa caagagggaa ttgtagctgg 413700 aagacagtag aagagccata ggacaagtct ctaagagaag gaagaaaagg cgcaatgaaa 413760 gaaaacaagt ttaagatagt agaaaagcat tcaaagacgg caacctgagg taaggtgttt 413820 tcactgaagc ttttggggta aaacagtttt gagttggcat gcctgtagac atgggaagca 413880 gcagtgatgc agaggtgaac attactgtag ataaaaacgg atgggaattt gacttgctag 413940 ggactgaggg gttaatcata taaataaaga tggcagcaga tttgggaaag agtgaagaag 414000 aataagttca ggtagcagtc ctcaaaaacc gagaagaaac tgatagctca ctgaaggcag 414060 acagaggaag acaaaaccag aaggcataag cttcaaagga gcagggattt ttatgctgag 414120 agagtaaaag gaatagttca aagcagcagt ggagaacacg aataacgttc catgtgggaa 414180 aagaacatgt ccagagctta ctgtacctat aacctagctt ctgtaactgg aaatgaagaa 414240 tctgctctag tcaggtcatc acttttcact acttatttta cttggccttc ctaagaaata 414300 tagacctttt ggaaattatt gacttttggg tctaggacac tatttcttgg tttcctccct 414360 tctctctggc tgtttttcag agacttccct tccaaatcta gagacatttg tattctccag 414420 ggatcagcta ttagatactt tcccttttaa atttcccttt ggacagtttc atctttcaag 414480 gattgagcaa taactaaatg acttccaaat gtctacttca gtataaattc tgcttgtcag 414540 gctacataaa aagggctctt caaggaatta tgatgtctaa agaaagagaa agccacgatt 414600 tcaatatcac agagatgact acagaggaat agcaataaaa agagaggcaa cttaggagag 414660 gtgaatcaca aaagatgact aggagctgat gacactatgg gtgggaagaa tgtttcagac 414720 aggggaagaa tgtttcagat agaggaaaat gagtaaaagc acaggggcct gaaaacatga 414780 tattataaga caattccaag cacttcaaga gcctaaagtt caagaaaagt ttcaaaaata 414840 tgaaaatgga gaggcaggga aaagccagat catggaagac ctcaatagcc atgataagta 414900 attctttttt tagccaaaag aggagtaatc taataaaagc taaagatctt ctcctcataa 414960 aaatacatgc acacttcagg agtgcaaatg cactcttccg gaagattcgt aacccactac 415020 attcataaac cattagataa gaactaaaac acaaggagtc actgaagggt tttaagcagg 415080 ttaagtgact gacaaaattt gccttttcaa taactgaaac caaagtgggc aaaactggag 415140 gcaagcaatc cagttaggta atgactactg taatagtccg gacaaataat gtagcagtag 415200 gaagaaaaaa aaagatgaaa ttgacccagg aaatatttaa aataagtagt ttgtaagagg 415260 taaataagct ggaagagcca gaggtaatgg gtagggtttc tggtatgggc aacaagatat 415320 gctacaagct gagatgttag taaaaacaag cgttcatcag catttagtaa gtgatttatt 415380 tatattatat cactgaatac tcaattatgt taagaggcag acagcagtta aaaaacaaag 415440 aactcggtga atcaaaaagt tctgctaatt tggggaaata gcatcccttt tatttttgtt 415500 aatctctttt gggtttgatc ctcatttata gctgacaaga agttctatgt actaaaggta 415560 aactattctc attaatgttc ccaaaaatct cttggaataa ttaagatata aagaaattca 415620 aaattcacat gattataaaa atctttcctt agataatctc ataatatagc catgttttgc 415680 tcattctact ttgagaagat tcagccagaa acagttcatc cattcaacta tccctactgt 415740 gaactagaag tatgtttcct tacatttgaa acagaagata taggtttata tgatgcttca 415800 ggtggtagaa aagcagggca gactatgact cgtgtcactt ccttccacac gtgatgcctt 415860 tcatgggctc ctgtgtctgt cagaagaaag caaagggcct tagcgtgctc ctggctttct 415920 atatccaaat gcattttttc acaccttctc ccatcagcta actctacatt actgcaatac 415980 ggaacttctt actactcagt ggacttgttc tgctgtcttc tctgattcca ggtgttattc 416040 ttcctgccta gaacactatg attcttagct attcccaagc atcctcaagg tttcagctta 416100 tataccactt ttaagataat taggtattct tcctctgtag tctcatacca accagtacct 416160 attctattat atataataac tgcctattaa ttaaatggga agctgaggta tatgacctaa 416220 taacttattt actgtcgtat cctcagaacc tagcaaatta cagagtctca acagagattt 416280 ttcaatttct cttctgatac tgtctcgata acagtgtcaa ttaaaccttt ctctaattat 416340 ttgaccttga agggaaatag atgtcagact acctcctggt ttcgagtata ctggaagcat 416400 acaaaaggac cttctcaatc tggagaccaa gaatatgata tgagaaccta taggagaacc 416460 acttatttga ttaaagagat ttcttttact tcagaaaata tttcagtatg ttacttgacc 416520 cataaatgct tatagatgtg taagtacacc gaagaagtca tataggaaat aaaagcatcc 416580 aagctatatt tctatggtct actctgatta aaaagctcag ctctcctatc aaattcaaga 416640 taatgcatgt ggattatgga gcacagtcac ttgctacatg gtaaatgctc aaaaagatga 416700 taggtggtat tacccacatt ctacaggctg tgtacatact tatcagttta tatatataca 416760 taaactgatc ctaaaaaatt cttcctacat ttctgcaaga taattaaaaa ggcagaaaca 416820 aacattttgc ataaatttac tagcttcatt ctttcatgta ggaagtagtt actgactacc 416880 tactgtatgc caggcactgt cattaggctt ccattctagt ggtaaagaag caaaacaaca 416940 aagaaatcaa tatgcaagaa gtcaaatgac attaaatccc atgaagaaaa atgcagcaag 417000 ttaaggggaa tgcagaagaa catgatcatt ctttgatgca gccggtcagg aaaagcatca 417060 tttgagcaga gagctctctg aatcaagtga ggaaggaagc cacatggatt atcacagaga 417120 agggtcacag ggtcacagac aatagttaca agccttaaga tgacaaagat acagccattt 417180 tagacagaga tgagcaagtg cggtagagag atcacagaaa tgaaaggaag ccagttcaca 417240 cagggccatg taaatctcca gattttactt ttaagatggg aagcctctga aaagttctgt 417300 gcatagtaaa taacatggtt taactcagat tttaaaaaga tcattccggc tgctactaga 417360 gaatacactg taaagcacaa gactcctggg aaacaatttc tttcttttgc caaaagatga 417420 tgcctttaaa cagagtaaac agaagtataa tggttaaaaa aaataaaatg aattatgggt 417480 atttggaagg tgtagccaac aagatttacc aataatttga gtatgtgaca tagagaaatt 417540 aaaagatgct tccaaggctt ctggctgcac aggaggggaa aaaagctgtt attgactgag 417600 atggcaaaat attatgagag acgtaggttt gggatgatga aaatcaggag ctccacttag 417660 gacaggttaa gtttgagaac cagacttaac tgttggataa atcagtctac agttcagagg 417720 gcaagagctg acgatggaaa tagaagagtt gtcaatagac agagtcctgg ggcatttctg 417780 acatttacag taaactgagc atttattaaa actaacttgc tttactgaac cataaatcac 417840 ttgttgtatt tacccctgct ccatttatag ttatacatct ggaaacatag ccttagtgtt 417900 agaggtaaag agtaaatacc aaacataaaa aatctgatct ggttgggtgc ggtggctcaa 417960 gcctgtaatc ccagcgctct ggaaggccga ggcaggcaga tcacgaggtc aggagttcaa 418020 gaccagcctg gccaatatgg tgaaactctg tctctactaa aaatacaaaa ttagccaggc 418080 atggtggcac atgcctgtaa tctcagctac tcgggtggct gaggcaggag aattgcttca 418140 tcctgggagg caggggttgc agtgagccaa attgcgccac tgcactccag cctgggtgac 418200 agagcaagat tccatctcaa aaaaaaaatc tgaagttact gagaaactgg tatgaaatca 418260 ttaagaaaac taaggtgtct aaattaatac atacaaagag attctacaac acggtattta 418320 taaatttaaa caaaatccat ggccaggcac ggtggctcac gtctgtagtc ccagcacttt 418380 gtgaggccaa ggcagaagga ttactttggg gccaagagtt caagaccagc ctgggcaaca 418440 tagtgagacc ctgtctctac aaaaaacaaa caaacaaaca aaaacactgt tttagcctgg 418500 catggtggca catgcctgta gtcccagcta ctcaggaggc tgaggcatga ggatcacttg 418560 agcccaggaa ttcaaagttg tagtgagctc tgatcacacc actgcactct agctgtatca 418620 cttatgacag agcaagacaa tatctcaaac aacaagcaaa caaaacaaaa aactaaagta 418680 aatccaggta aaataaacat acgaataaat gaaaagatct gggttattgc attagttctg 418740 tttctaggct taactacaaa atggtgtcca gttgttaaaa acacttgttt aagagtatta 418800 ataatttttt tttttactat gctcttctac atcctaggaa attggcaaca ctaagaattc 418860 ctaaaaacaa acaggagtgt taactgtata taaattatta tttaagatgc attcaaggcg 418920 ttacttaaaa tatcaaatgc atgtcaaagt acaaacaaca aaatcatgct tcaacaaatg 418980 tgggatgttg ccattaatgg acagttagct ctgaggtaaa accaagaatc cttcattacc 419040 tatttttgta aattaggaca aatactatta aggtattagg ttggtacaaa agtaattgaa 419100 caaacctgga cccactcacc tcactgaaag tgctgcctgg ctacagtttc tagatatagg 419160 aatgtgagaa atggtagcag ccttgaaggt ttagagctat attcccatac caattatggc 419220 tagaaactta aaacagctct attgagacat tatgggaagt ctaatttcct gttactctac 419280 tttaacacag ccaagtaaaa cagtaagaaa gcttgcttaa ttcaacaagg actgagtgcc 419340 agagtgtcac ctggaaactt gtgacaaata atcatgcctc acacattcat ccttggtttt 419400 tactaccaaa tgcaagcttc atctatcctc ttccattcta aacttgactc atcctcctaa 419460 cctcttccag aaagatctct agaaacccag aggctttctg aagacccata ggctatcccc 419520 catcttcaac tactttacat aatggcccct caacttctta gctttcatga aagcctggct 419580 cctccccaaa ggcactgcct atcatgcaac ccttttatgt gactcctaaa actcctaagt 419640 ccaccattat tcttctaatt ccctgtatta aaaataaacg gcaaaattcc ctgtattaaa 419700 aacaacaaaa aaacagcttg taatttgaaa ctcatgtcat ctaaccgaat gccttctctt 419760 tccctccctg ttctggtcaa ttaaacccac atatttaagc ctccactttg cccccagtta 419820 catcatcagc aaagtgactt caatgtccct gtacatggtt ctatcccaat actctaggcc 419880 cccaaaatat ttgcctttct aaatttgaga catcttcacc tcctcatttc agcaaatcac 419940 tcccttgtct ttgttagaca tactaaaacc tctgacaatg atcatctcag ctatctttgt 420000 aagagtttca ctcatactca tatctccttt cacctgtcaa gacaccaggt ttggtgacaa 420060 ataaaaatga tacgtatttg ggaggctgag gcaggagaat catttgaacc caggaagcag 420120 aggatgcagt ggccaagatc atgctactac actccagcct gggtgacaaa gcaagactct 420180 gtctcaaaaa aaaaaaaaaa aaaaaaaaac acaaaaaaca aaaaaaagga tacatattta 420240 ttgtattcac atgatgttcc aaaatatgta tacactgtgg aatggctaga tcaagctaat 420300 taatacatgc aatacctcac atacttatat tttatggcag aacatttaaa atctactctc 420360 agtgatttcc aaaaatacac tgttattaac tagtttccat gttgtacaat agataccttg 420420 aacaaattcc tcttaattga aattttgtgt cctctgacca acacctctgc aacccagtcc 420480 actcaccccc agcccctggt aaccaccatt ttacatccct gagttaagat tccacattta 420540 agagagatgt agtatttgcc tttctgtggc tggcttactt tcaacaatgc cctccaggtt 420600 catccctgct gtcacaaatg acagcatttc ctccttttta tggctgaagt atattccact 420660 gtgtatacat accacatttt ctttatccat gaacacttag gctgatgctg tatcatgggt 420720 attgcaaatg ataccgaaag gaacatggga gtacagatct cttcagcgca ctgattttat 420780 tcttttattt atatatatat atatatatat atatatatat atatatatat ataaaaatac 420840 atatatatcc aagtgtgact gctgaatcat atggtagttc tattttttaa tttctgagca 420900 aacgtcatgc tattttccat aaatgctgta ctaatttaca ttcctgccat gcgcaatata 420960 tctcttgtct gcaaatcctc atcatacttt aatagccatt ctaatggcca tttgtatgtc 421020 ttattttgag aaatgtctat tcaagtcctt tgcccatttc ttaagtgagg tgctttctta 421080 ctattgagat gtctgagttc cttatatatt ttgcatatta accccttacc agatatatgg 421140 tttggaaata ctatcttcca ttctgtgagt tttttcattc tgtagatttt ttctttttgc 421200 catgcagaag ctttttagtt tgatgtgatc tcattcatca atttttattt ttgttgcctg 421260 tgcttcgagg gggtcatatc caaaaaaatc actgtccaaa ccaatgtcat gtacatttct 421320 cctatacttt attctggtag ttctacagtt tcaggtctta tatttaagac cttaatccat 421380 tttaacttga atttggtata tgatgtgaga tacaggtctg atttcattct catgcatgta 421440 gatattccat tttcccaaca ccacctattg aacagacttc cctttccccg ctgtgttctt 421500 tgcaccctgt ccaaaatcaa ctgatagtac acgaatttat ttctgtgctc tccattctgt 421560 tttgtgggtc gatgtgtctg tttttttgtt tcttttgttt ttaaaagaca gggtctcacg 421620 ctgtcatcca ggctggagtg cagtgatgca atcacagttc actgccacct taagctcctg 421680 agctcaagca atcctccttc ttcagcctct cgggtagcta ggactacaga tacacagcac 421740 cgcgcctggc tttaaaaatt tttttttttt ttaattttag agacagggtc tcactatgtt 421800 gcccaggctg ctctcgaact cctggtttca agtaatcctt ctgcctcagt ctcccagagt 421860 gtgggaatac acgtgtgagc aactgtgcct ggcctgtcta cttctatgtg actatcatgc 421920 tgttataatt actgtagctt tgaactatat tttgaaatca gatagtgtga tgtctccagc 421980 tttgttcttt tcactcatga cagctttggc tatttaggat cttatgtggt tccatataaa 422040 ttttagcact gttttctagt tctgtgaaat ttaacattgg aattttgatc aggattgcat 422100 taaaactgca gattgctttg gataataaaa acattttaca atattaattc ttccaatcca 422160 taaacacaag ataactttcc attatttgta tcatcttcaa tttctttaat caatgttaca 422220 tagttttcaa ctctttggtt aaagttattt ctaagtacaa tcatccctcg gtatctgcag 422280 gatattggtt ccaggatctc ctgtagatac caaaatccat ggatgctcaa gtccattata 422340 taaaatggta tagtatttgc atacaaccta cacacatcct cgtgtatact ttaaatcatt 422400 acttagtacc taatacaacg taaatgctat gtaaatagtt gctatactgt agtttcctta 422460 ttgtataaga aaacagtatt tttattgttg tatttttttc tcaaatattt tcatccaaat 422520 gttggttcaa tttgcaaatg cagaaccact gatactggga gccactgcat gttttgtttt 422580 tggtacctat tatacatgga attgtcttct tgatttttct tttagataat ttgtcattaa 422640 tgtacagaaa ttctacggat ttttgtatct tgattttata tcttacaact ttactgaatt 422700 tatcagttct aacaattctc tggtggagtc tttaggtttt tctatataca agatcatgtc 422760 atcttcaaac agggacaaca atgtcttcct ttcctactgg gatgcctttt ctttctcttg 422820 cctaattgct cttgcaagga cttccggtac tgtgctgaat agaaatggca aaagtgggca 422880 ttctcgtttt cttcctgatc tcaaaagaaa agcttttaac ttttcaacat tcagtataac 422940 gttagcagtg tgtttgtcaa tatggccttt attttataga ggtacattcc ttctatactt 423000 aattttttaa aattttgtag cacaagagaa tactgaattc tgtcaaatgc tttttctcaa 423060 ttatctcaat tatctattga aatgataaca tggttttggc ctttgttctc ctaatgttgt 423120 atatcacatt ttatggattc aggtctgttg gataatcctt gtacccttga ggtaaatccc 423180 atatgatcac agtaaatgat ccttctaata cactgttgaa tttagttatt attttcttca 423240 gaatttctgc atctaaatta agaatacggg tctgtaattt tcttttcctg gagagttctt 423300 gtctggcttt ggtatctagg taatgctcat ctcccaaaat gagtttgaaa ttactccctc 423360 ttcttaaatt tctcataaaa ttatgagaac aatctgtact agttcttctt taaatgtctg 423420 ctagaattca gcagtaaagt caccaagtct tgggcttcct ttggtgggag atatttttat 423480 gactgataca atccttgtca ctggactgtt cacatttttc atttcatgat taagcttgga 423540 caagttgcat gtgtctagga atttatccat ttcttctatg gtaatcaatt tgttggcata 423600 taattgttca gtctcttatg atcctcttat ttcttgtact tctctggtat cagctgcaat 423660 ggttcctctt tcatttctga tttaacttga gtcatctctt tttttcttag tctagctaaa 423720 gacttgttgc ttttatcatc aaaaaacaca actctttatt ttttttatct tgagtcatct 423780 cttttttcct tagtctagcc aaataacctg tcttttgagt tcagattctt ttgtctgctt 423840 gctcaattct gcttttaatg ctcttttgca tttttcattc catttattgc attttcagct 423900 tcagaatttg ttaaaaaata atttcaatct caaaatttct cattttgatt gctgttttcc 423960 tgattttgtt gaattgttta tctgcatttt cttgaaattc attgagcttc cttaaacaat 424020 tactttgaat tctttgtcag gcagttcata tatctccatt tctttatggt tggttcaggt 424080 gccttattgt gttcctttga ctggtgtcac gtttccctga ctgttcttga tccctgtagt 424140 catgtgttgg cacctgcaca tttgaagaag ctgagacttg ttccagtctt tgcagagtga 424200 ctttattggg taaagccctt caccagtcag cctgtccaga gattatgcag cctgagtcta 424260 ccggggctgg cctggagtct gggtcagcag ggtaggtcct ggagccttgg tacacaggtg 424320 ctgctggcct ggcatcctgg tctactagag tgagcctgaa ccttggatct gcaaggacca 424380 gtgtgaaggc tgggtaggtg gatgttggcc tagaatttgg atcacaaggg gctggccaag 424440 tactgggttt ggacccttgt tctgcagtga tgtgaggcca caggggccga tctagagggc 424500 agggctgcag ggaccaccct agcactagac aggcttagag cctagggctg tgggatccag 424560 cttggtgctg gggtgggcct ccaagcttgg tttgtgggta ttggcctgaa gtttggggcc 424620 atgggggcct gcctagcatt gagttttact ggggcgagct caatgttagg gtctaagtct 424680 ggtgtacact tcccctcctt cccccaggtg aacagtctct ctctccatgc tgggatctca 424740 gggactgagg gaggtgtgac acaagtaatg taaaactgtc cttcttaccc ttttcaatgt 424800 gtcttttctt atctgtgtgc cacattcagg taatctctcg tctggtttct tagctcttat 424860 atttttgtgt gtagacagtt gttcaaattg atggttctac aatgagatga gtgctgcaaa 424920 gtgctagtct gccatcttgc tgttatctag acctcaggct tttcttaaaa caactcaaca 424980 ctttggtctg gcatcccaac ctttccaatc atggccatca tccacagcat ataaattcaa 425040 atactccaat gttaacatct tatgcacatg ccactaatga ttctgttcca tcagctctgc 425100 taatatccaa ccctaaaata ccatgcataa tcttctggct attggagaaa agtctttaaa 425160 tttcaaatgt gataaagtct ttaatcttaa ctagtcactc agtggaatga gattctccta 425220 ctctgatacg gtttctgatt tcaggtagcc agccagtcaa gactctcaac ttctgatcca 425280 cttcttcacc cattcccctc agtagcttcc taagttttca gtcttctcaa aacctctaaa 425340 caaaccttgt attccacaaa atattattaa aaaatgtttc ataaaaagtt tcgtggtcac 425400 taacctacag taacatacta ccttatatcc actacaatga ctactattga agtacacaca 425460 cacacacact ctcacacaat atgtgatggc aaggatgtag agaaactgga ccccttgtgc 425520 actagtggta gaaacgcaaa taggtacagt tgctctggaa gagtatggca gtttctcaaa 425580 attttaaaaa taaaattacc atatgatcca acaattccac ttctgggaaa acaattcaaa 425640 gcagggtctc aaaaagatat ttgtacactc ctgttcatag caacattatc tgtaatagct 425700 acaacatgga agcaacctga gcgctcatca acaggtaaat ggataagcaa aatgtggtat 425760 atacatacaa taaaacatta ttcagcctga aaaaggatgc aaattttgaa acatgctaaa 425820 gatggatgaa acttgatgac actgcgaagt aaaataagcc aatcataaaa gggcaaaaac 425880 tgtatgattg cacttatagg gggtacttag agcagtcaaa attagacaca aagtagaata 425940 atggttgtca gaggctgtga agataaggaa atgaggaatt attgtttaat gggtacagag 426000 tttcagttct gcaaaacaga gagttctgat cgtgactgtg caacaatatt aatatactta 426060 ataccattga gccaaatact taaaaatggt gaaatggaaa attttacatt atgtgtattt 426120 tactacaatt ttttaaagct taaaagacaa gtcacatggt tgggtcacat aaatttgaga 426180 aatacatttt atagtcgttt cttgcagatt cacaatatat accggcattt aaataaggtt 426240 ccaatatttt cagtaaaaaa atcttgattt ttccaccctc acccacaatt acaattaata 426300 tcacacatcc atctttactt ccttgttcta atttcattag atgggcatct ttcctcttat 426360 tcaaggtcaa tcactatatc tgcatttttc tttttttata ttacctgtat gagagataca 426420 cctgtatttt tcattccaac ccttaatacc tcgaaaaact ttgctttgat aattactacc 426480 tctattatct gaaacatctt tagtcttcac aataaatcac taaagtctta cttacttcat 426540 gtcctaaata tttgtcttaa atccagaaaa atttattttg aattcctatt ataccactgt 426600 cattgtcaag gctctcactg actgaactac cttaccacca cacgtttctc ttcaatcctt 426660 tctctcttgc aaggttatta aaaatacacg tttgacaaac ttactatcta cctactgagc 426720 aaattctttg ctgactccct aataccttct atcacatctt atcttcttca ttttcctacc 426780 tctcagctag tttatgatct aaaagtcctc aactgcctat tgtcccctac tccctatgct 426840 gcttctaact ttggctcata cttctgcctg gaataagccg ctcatgcttc tagctgcctg 426900 attcccagtc acatttcaag actgaactta gcatttcctg gccactctta cttccctgcc 426960 atctacacta gattcctatt gcatacctgg gtactccagt actccttcat gttactattg 427020 tattttggat accattctac ctcagtgact gaaattattt gcttctgcat ctttcactct 427080 tgagtataat ataaatttct gtagggtgaa aactaattat tacgcatctc tgtatctata 427140 acatagtact tgatgcctta aatatggtag gcgttgagac tgttaaactc aactctttcc 427200 tcaacctccc tatttcccta caactgctac cagggaagca aaaagactaa gaatttaggc 427260 gtgtgcattt atctatctag tagtagaaac ctagtaaact gttaccgagg tttagagtta 427320 tctgatagga aaaaaagtag gtatgttcct atctcccatt tactgctaaa tgattccttt 427380 cttttaacca gaaattattt ccaaataatg tgacgtaatt taaagcagtc tagggcaact 427440 caaaataaga accacagtct caaccaagtt acacttacat tcggctagct tcaatgtcgt 427500 cagactgagg ttctcctgat ctgtaaaatg caattgagaa acagttagca aaatattcca 427560 tattccaaaa aaaaaggtag acatattact taggaagaca attttgtaaa caagatttaa 427620 gcactaaata aaacagtttt aaaattaaag atgtcaacat gaaagaaagt ggtcagatca 427680 ggtggccata caacacattt attttaaggg ttggactatt aaaaaactca atgcatgttt 427740 tttaaaggaa actgtaaacg ctatacatag ataccaacag acaagccatt ataagccata 427800 attattcaca aagtcaaata cgtgtaataa aacacacaac taaaaaactt cctatagcca 427860 agtattggtt atccacatta acaaaggtac tcactggtat tcactcacag tattaaactt 427920 tagattagtg gctcagtaaa ctactcccta ggcagacaga ctaaagctta ggccagccat 427980 gtagttttgt aaatgaagtt ttattgggat gcagccatac tcattcattt aggtatcatc 428040 tatggctgct ttcacactaa aagaacagag ctgaggactt gtggcagaaa ccacatggcc 428100 cataaagcct aaaatattta ttttctggcc ctttaagaac aaatgtgcca accgctaccg 428160 ctactccaga caattcaaac taaaatctaa taccttggta agtttaaaga cacttaaatc 428220 agatacaaca ttctaatgat gattatcttg gttcaacaat gaaactgttt ccctaaaaat 428280 acacttactg tatgtattac ctgtcaaaag tgtatcacct gaggtgaagt tttgcactgg 428340 atagctgtga attaacttca gttttaaaca gttgccagtt actttgttat ttctaaatat 428400 actactgctc tctcatgtag aaatatttaa aattctaagt cactaaaaag cctttcattt 428460 tcatttcacg agatatgaat cagtatttcc ctatctattc acttttataa acagcatcag 428520 caacaatgaa tgagtcaata taatattgat ttctaacact tagaaattcc caaactagat 428580 aaaaaatgtt ttttgaggtc aaaagctaaa ttttcaaatt ggcattacaa agtcctgatt 428640 tgtgaacttc tcactgactt taggcttcca actttaagca actctaacaa gaatcttaaa 428700 atcagtcaca cacacacaca cacacacaca cacgcacaca cacaaacctg ttttctaaat 428760 ttcttagcta aaaacaaaaa caaaaacaaa aaacaacccc tcacttcttt atcagactct 428820 caaaattacc ctcactgcaa ttcattcaga ttccaaggac aagaatggaa aaggaaaaaa 428880 aaaaaaaaaa aagactccag cagctcaaat atttatttta gatcttcttt gcaatgtatt 428940 taaattttca attttgcaca aaattacata acaactaaaa actggggcat gctggaggtg 429000 gcagtgactt ggctgtgaca caaatgcaaa aatttcactc caccctctcc cccagggagc 429060 aagcaaatca cctatgtgac acacctggtc tccaccagcc ttgtgggtaa gtaccccaag 429120 attgcttcca aacttgtatc tcccagacag aagagctaaa aattgatgat aaccccatgt 429180 accagctgac tcatttttga aagtgcgacc ctccagcatc agatgtcata ctgtaaggag 429240 gcagagctgg cttgcaaaac aaaaaataaa cctgctggca ctgagggaag agaggcagat 429300 tagaagtttt caaacacgta ggcagcaaaa ctttcaaaat taacagggaa agagaagaga 429360 gggaaaaaat gaggacatga tgataggaaa ataaaaatat tactgcaaaa aggtaagaca 429420 caagaagaaa aacaaatcta agtcttagaa gtacaatatg taactgttac aaagttttga 429480 gatcctgaaa tgggatagag tttaaataca ttatcaaatg ataactacat ctatcttccc 429540 aatttctgtt ccctaagcaa gagaatatgt gaactttggc atcaaaatgt ttgccaccaa 429600 actgtaacat attaattact actttttaca tatattaaag taggctatta aaaaccattg 429660 ataagacaag ctaagtaatt taaaccaatc cagtatagaa gaagaaggat tgaaagatta 429720 ttaccttaaa ataaatctgt cctgggtcta ttaaacatag caaagttgtt ctactcaaat 429780 tggaaattgt tttttaatca agagaaaaat gaatatatgc agaactagca gacatttttc 429840 ttgcagtaat ttataatagt ttctgtctga atgaatttct actcatccta ataacagtat 429900 atttctagaa tattataaat aagttaccaa agtcccgagg ttagaattca aactctcaaa 429960 actatgacat atgccaggtg tggtagttca tgtctgtaat ctcagcactt tgggaggtca 430020 agacataagg accacttgag ctcaggagtt caaggtcaac ctgggcaaca tgatgaaacc 430080 tcgtctctta gccgggtgtg gtggtgggtg cctttagtcc cagcaacttg ggaggctgag 430140 gtgggagggt cacttgagcc cagaaggtca aagttgcagt gaactgtgat cgtgccactg 430200 cactccagcc tgggcgatgg agtgagacct tgtcttggaa acaaacataa actatgaaat 430260 atataccacc tagcaacagt tcccaagctt gactttggct cctaaagagt ctacttattc 430320 ttttactgcc aagttgctgg aagtaagaat cctgtatgtg cttgtaaatg cagaacatat 430380 aacctaattc aaaacatata accaaaggga aatttttgta ttaaactatt gacttaggtt 430440 atcctaaagt gtgtcagaat aacaagtcag aaattttaaa actgaaacaa taaccaaata 430500 acattggata ataaaatgta aatctcagaa tgagaatcaa ttttaggtct tgatttgaat 430560 cgcagaaaat atgatcacaa aacacccact aatctgaata ctgcagcatg agctagcaaa 430620 ttcaaatggt ggctcacttc caataacact ggtgcagctt ctccatcctg caagccactc 430680 cttttacctc cactgtaact ctctaggaga gaaaagtata ctagttttat taatgttata 430740 aaaacttcta gagaaatgtt tagttaaaac gttcaccaca taaaaggcat actttaaaat 430800 gcatattaag aaatttttaa tgttttctat aatgtttata gtaaaatgtt taaaaccttg 430860 aagttttttt gagaaatact ttcctgttta tacatacaga taggtctttg atagtggcta 430920 ctgatatttt taatgagaaa aaaagacact aaaatatttt aaggagatta aatgaagtag 430980 gtcaactctc aggcccacta ttcttagcag tattcctgcc aactatacat tgtcttcatt 431040 tttacagtat gtatttcact ttacaatgac agccttttaa aggctgtaaa ataattcaaa 431100 attacctttt acaagctgtg gccattcggt gacatcaggg tgatcacagc tttgagtcac 431160 tgattaaaaa caggttgtca caccagtcta gctgctacct tgatctgagc gtaggcttaa 431220 taactctaat aaattaaaca aacctttggt tagaacactt taatatataa acccaattca 431280 ttgttcaaaa aataatattc aaagcttcaa attaggtgtc aatgtaaaat tcatcagaag 431340 agtaattatt atagaaaagt ttttaaggac tattttccag cattttgttt ttcttaaatg 431400 atctcttcat ttgagaaaat gtaataattc cttgtacttt tatgtaatgt tatagtttct 431460 gaagcatttt ggtcaatagt accttgagtc ttataacaac tttggcttta cctaatcaag 431520 acagataata tactaagaat taaaaaaaaa aaaaattaag cagcctccga gtgattaact 431580 gacttgccca agattttgga actagtgttg aaggactgac taaaacccag atatactgac 431640 ttcctatcaa gggatggatt tttttgtttg ttttggctta gttttgctat actgggtttc 431700 aagatttaag tatatgtaaa tgagtaaaga ttcagaacac agattgagat ctttcaaata 431760 cggacaaatt cagtcaaaag attcctaagc tgatagagca atcagtcacc aaggagggca 431820 actgcttaat ggaatagtta tatacataca cataaacaca cacacataaa cacaaagtct 431880 agtcccacta attctgtatg tacgtaaagt catttaacat cagtcaccgc atgttctcac 431940 tcacaggtgg gaactgaaca atgagaacac atggacacag gaaggggaac atcacactct 432000 ggggactgtt gtggggtggg gggaagggga gggatagcat taggaaatat acctaatgct 432060 aaatgacgag ttaatgggtg cagcacacca gcatggcaca tgtatacata tgtaactaac 432120 ctgcacattg tgcacatgta ccctaaaact taaagtataa taataataaa aaacatcagt 432180 caaaacccct taagtactgc ataaaaatat attctactct ttcttggcca taaatctact 432240 aagatttaat ttcatgaaaa agtatggcaa aagatgaaag catatcctcc tccctcaacc 432300 aaatatcttt ttaacccctt acatggcctt agctgaactt ttctgattgt cacagttcaa 432360 atttagcagg cctctttact gacactgtag ttctggcaaa gataccatac atctgaaata 432420 tcccagtatc aaaagatcat tttgtgcaac tagttctttc ccctcacgat tcccctatcc 432480 aggccaaatc tgaggcatca actacggaaa gatgaggaaa ttaggaggaa gaaacctttc 432540 ataattaaca tcctcaaagc aacaatagtc aagcgtaaaa ggtggttacc agtgtggatt 432600 cagaacccaa tataaaacag caaggtatct gcgaatacca acggttaaaa catgaatgtt 432660 tgagcccata cctatgcagc tatgaacgca gggcttcaaa atccagatta ggtgaggatt 432720 ggcctgaata tataaaaata attgcagggg attccaataa atgggattta tagtatctgt 432780 aagaaataac gcaatctccc agatactcct atcctaacta tacattgcct aataagaact 432840 tagacattgc tgaggtcata tgggaaacac caccttccct aaaataaaca atgtggtcat 432900 gatacagctt ccccttgggt tctcaagaga ctaatggtat gtggaattag aagattcaaa 432960 caagtctaac tttccatctt gtaaacacaa aaataataaa gttaaaatat cttttaattg 433020 actaattgac ctcaatgtaa ttaaagagct atatgtattt tgaaaactag agtcaagtcc 433080 tctcttccag tcccctcttt tatgagatcc ggtgctcaaa aggctccaag gccaggctgg 433140 acttatgtct ctgtttggtc attcactagc tgagaaatct tgggcaagtt acttaacctc 433200 tccgagtctc agtttcctta taggtagaac taggataata gtacctattc catagagctg 433260 tcatggataa acaagctaac atctaagtat ctcagaacag tgcctgacat aatgtgctca 433320 caaatggctg ggcgtggtgg ctaacgcctg taatcccagc actttgggag gccaaggcgg 433380 gtggatcact tgaggccagg agttcgagac tagcctggcc aacacggtga aaccccgtct 433440 ctactaaaaa tacaaaactt agccaggtgt ggtggcacac gcctgtaatc ccagctacct 433500 gggaggccaa ggcatgagaa tcacttgaac ctgggagatg gacgttgcag tgagtcaaga 433560 aggtgccact gcactccagc ctgggcaaca gagcaagact ctgtctcaaa aacaacagca 433620 gcagcagcag cagcaacaac aacaacaaat gaaagctatt attaatactc atagcccaaa 433680 atccaaacct gccctctcaa tctttttatg catattattt tacctctcat agcacactaa 433740 tctcttgtaa attttttcag caccctacct gggtccctca tacagtcttg gaagtgtagt 433800 tagtgagcac ctgacacaat gctttaaaaa tggcaggggc ccaaatttgc tgaacacatc 433860 tgtcattatt atgacattaa gatacacatg caatacgaat tccaaaaaat aaaacaaaaa 433920 cataccatat ttcgccaaac ttctgaggag ctggtgaatt ctaaaatcag gctcttacag 433980 atttttaacc taaaatataa aacacctcac tcaattcttt ttacataaac aactggatga 434040 actttcaaaa aaaaaggtac taaatttcat cataaaggca aatttatttt ctataattat 434100 gaacatccaa aaacgtatca agaaacaaat tactgctgtt gccgggatga ggaaagcata 434160 ggtaggcagg ccctgtggcc tgagtgcttt cagcaggcaa agccatattt cccatattca 434220 tccataaagc ttagtgcctt ctatttattt actctatcct ccctccaaaa gggctaaaca 434280 catatgaaaa ctatttgact atatccctct aatcctttca aatacctata gcaattttgt 434340 ttttaattaa attctatatg ctaagcatcg gctatgttag gtacaaatct gggcatctac 434400 cactttctag agtagcagcc ttgggccgac cctctgaccc ttgagtctcc aatgtcaggt 434460 tattgtagca gagaaaatgc gttaaaaagt tatagtataa tgcctacctg gcacaaaaca 434520 ggacttcaat atacgacgat aattataatt tattaaatca accacttaat atatatcaaa 434580 acttaactct taaaaaaaaa tcctgaagct taaagcaagc ccctaaatta tcactgtaaa 434640 ttcttaactt gtttgtatac aatcagaaca ttcctcaatg gaacaaaaat aaagtccttt 434700 catgtactgc attacatata aagaaagcaa atctcaaagg ttaagaaacc tatccagtgt 434760 cctagaggtt gatggtagaa agtgaataca ctgcatataa aacattttga aataaaatta 434820 accaactttt aaggttttag agactgactt tcaaacttca gtctataata gaattacctg 434880 gggaaatcta aaaatgcaac tacttgggct ctactcgcaa agattttcat tcagtgcatg 434940 aagtaggggt aaatgaattt tttttttaat ttttttcaga ccaacccaag aacgcagaaa 435000 tgaatttgca ttttaacata tacttcacat gacacacaga tctcatttta agaagccctg 435060 ccttccaaat tatgagttag gaacacataa tcatggagga aatataccaa atctataaaa 435120 atacagaata acaaaaactg taagcactac aaatattagg cacactcact tgccaattta 435180 accataagaa tcctaatacc agacatagtt ctcttacttt atctcttcaa cagagggctc 435240 agtctaataa tcttataaat aagtatagtc taataataaa tgcctatgtt gatctatatc 435300 tacctcccta aaattttcat tttattcatt tctatttttc cttcacctcc ttctaaagct 435360 gtttcaaaac ttaatttcac aaactgtttt tttctatcac tttttattat aacacccaac 435420 acttctgttc tcctttgcat catgtttatg gtgtcttata tttatggata atgctactta 435480 ttaaaactgt ctaagttttg tccgtttaca catttcacaa ttaaaggact actacaacaa 435540 ttttcctaag tcctcctgct ttagtttctc cttattccag tccattctgc agttaagact 435600 taaaaagttt taaatactgc tttcaaataa tacttgcaac ataattccct caactccatt 435660 agctcctcag agtaccattt ctttatcttc tttcctttta ctgccaaaaa gacgtgaaaa 435720 ccactagctc agctgctatt tttctatcta ctgaaatttt tcttgtaaag tttccatcat 435780 ttctgtatat tcccagtgct ttggcccctt aatcctactt aatttttgta gcttttaaga 435840 ctgctaatga ctcctcacct cctctggctt ccctaatgtt gtatccactc attttcttcc 435900 atctctctaa aggcaataag gtcttctgct agttcatctt cctacctcat acatggcctc 435960 tctccaagtt tctgtcaata gccacttttc ttaacctaaa ccaattttct gcgcaatgtc 436020 atccattccc atagcacctc tatgcttaca aacccctaac tctgtatctt taagtcctta 436080 tgtctggcat ggtatgcctg caactacata ttaccaacgg tacacatcca tttggatgtc 436140 tcattaacat ctacattcaa cgtatctaat atcaaactca attattttcc caaagaactc 436200 actctgccta atctcactgt cctggttaag gactaaaaaa attggtgcca ttcattactt 436260 tctccccctc atttttattt gccctaacca ctgtgtaggt tgatacttgt tcagccttca 436320 aattcttcat aatcattaat tcaaaaactg tctactagat tttgagtgcc tactaggtgg 436380 atgaagatgc agaggtagaa aaactagaca taatttcttg ccctcatgtg gtgaaggaaa 436440 tgggcacaaa taaaaaccac aattaattat gcaataacaa tgcacagtta agtgttgtga 436500 tggagagata cagggggtgt taagttgtgt actgtaataa aaagtcctta gtctgaagaa 436560 aaggaaaacc attctttatg agggacaagc aagatttaca agacacacta agaaaaaccc 436620 tgtgaggtaa tgatggtagc actatcagtc cagctgctca aattggaaga ttctcagtca 436680 tattctaaag agtctctctc tttcccagta tatcaaattg tttaccaatt gctaccaatt 436740 catccttaga aattccccta catttctaca ttctcacatt attccccagt cttttttgat 436800 tgcttttagt tgcttccaga ataaagccaa agctcccaat cacgtcagat gagattctac 436860 acaatttggt caaaacctgc cagtgcagcc tcttcttaca gactagacca gacttcaaga 436920 gaacatgtgt atcatttgct tttatacttc cagtgcttgc aaatgtttat agaataagca 436980 tcttacaaaa gagaaaattt ttctcttagg gaactagctt tcagtccttt agtaaatgca 437040 aggttaagat tcaaacccta atttgtctga ttctaaagac cacgcttatt cccttgtact 437100 tgccttctaa tttatactca aaccctatga atttccttaa aaatatctct tactcctttt 437160 ttcctcaaac ttaccaacac tgtcctacta cagtgcccca ttatttcatc tggtttccct 437220 tttgccttta tcctcaactt tgccactaga attatcttcc taaaaactca aagttacaca 437280 tatcattcta tattcaaaag ctttaacact ttctcatgcc aacagaataa atttctaact 437340 ccttcacatt ttatttgagg cccctgccat gtggccctga ccccagccat cccagcacta 437400 ctgcccacta tatgacatca tcaccagtta ccagatctag tcccatcatt tgactattgg 437460 ctataatgta ctggatattt gtgtttctga cttcaatgct tttgcttctg aggagacttc 437520 actcggaaat ggtcctctat ccattactaa cctctatccc ccacccacct atcatgccat 437580 gttaaaaact ggcctcattc taaacactgt atctcacagg gttatctaaa ctcttataca 437640 taatcaccat ctccttcatg tcttattata cattcttaat accataaaat aatttattaa 437700 tttctcctta tatttattat gttatacctt acattacagc tatctgtata catttgtcag 437760 tgcctctagt tgtaagctga ttgatggtag ggatcatctc ttccatattt tacttttcgt 437820 aataatggtg actatgtttt cttgacacca tacctcccct ctacaagaaa aaaaaaaaaa 437880 aaaaaaagga atcaggaccc atggcctttg agctagttcc aaatgtgact catagatgaa 437940 caaagatacc atttcttccc aaattaacac aaatataagt aaatgccaat ttaagaaacg 438000 ttttttcaaa gactaaatat gtaagaataa ccaaaacaat tgtttctaat aatgttcctt 438060 tctctaccag atattaaaac atattaactt aaatggaata attaaaatcg gcatgccttt 438120 aaaaaactga gtatacacta aatatatgca taccttatga cttaaaaatt tcactcttaa 438180 gtataccaaa cagaagtaaa catattcaca agaagacaat cactgaaatg tttagagcag 438240 cagcaatatt cttaacagtt ccaaaccaaa aatgattaaa tgtccgtaac agcagattaa 438300 actatggcat attcttaaaa tggaatatca cttccattct taaaatggaa tatacagcga 438360 ctatcataaa caattactac aaccaacaat gtgaataaat ctcacaaata cattaaaaga 438420 agtcagacac aactaaatgt gcttgattct agttaaagga tgaaaacagg caaatctaat 438480 ctatgctatg agaagtcagg acagtggtta cacatggaag aaaaggggta gtgacacaga 438540 gcacaagggg ctacgcagga gctgctgctg ttttttgatc tgaatgctag ctaaacgggt 438600 gctcagtgtg tgaaagtgca acaagctata cacttagaag tgtatagctt aaaacattct 438660 aaaaaaaaaa aaaaaaacct catatggtat tagcattaga caaagaggta agcacaacaa 438720 gcacaacaga aagctaattt cagagaaaga tccgaaagta tctgacagtt gctccttctc 438780 aaacgagaat tttcagacct tggataacag gcagcagagg actataatgc atgaaaggac 438840 aaaaacaaag gaggtgagcc atccactgct tggatgtctg cctggaggta atttccaacc 438900 tgcagtcaat ggaggggaaa tccagtgaga agacagcagt tttactgagt tcagaatcaa 438960 gagatcagag ctgagaaagc tgaagtgggt aaaattgatg acaagtgcca gacaagtgct 439020 tgtctgagaa ggcagagaaa tggcttcaga aatctgccat ttgagagtcc actgctgagt 439080 actaactgta cacgattaag gtaagtgact ccatgaagct agtgaaagag gggcagtaag 439140 ctgaaatatt cccagtactt ataaaggact gggagactcc taaaattctc tctaacctga 439200 gtgaagagaa cacggtgaca ctgggagcat ttagtaaaga ctcagaagga tcatgcctta 439260 ggtaggagct actaccatta aagcaaagcc ttctctagac aaactccaat gtagccctga 439320 agggataaaa ctgaccagca agttatttag gtggctacaa aacaaaacac tctaaaagaa 439380 aacaaaatct agacacccaa caacaaaata ttacaatgtc cagcatccaa tcttaaaaaa 439440 tcattaaata tgtaaaaaac aaaaaataaa ataaaataaa tactaggaaa atacaaccca 439500 tgaccaagag aaaaaaccaa ccaacaaatt cagagtgaaa aaattcaaga aatcaataag 439560 taacctgatt ttcaaacagc tattacaaat atgctcaaga attcaaaaaa atacatgaat 439620 aaaatgaatc aaatggaatt tcttgaaata taaagcgaaa tatctgaaat tatttaacaa 439680 gggaggagaa aaaacagtaa aatagaagac aaagcaaact gaagcacagg gaaataaaaa 439740 gactgaaaaa taatgaatat gatgttaatg acctgtggat aataccaaac agtctaacat 439800 atgtgtaact ggagtcccag aaaaagagga aatgatgaaa gaggagtaaa ggtggtaaaa 439860 aatatatata tagaagaaac aatggcaaca atcttccaaa tttaaggaaa accataaatg 439920 tacagattca aaaagaaaaa aaaaacaaaa ccccaacaac tctcagcatg gtaatcattg 439980 tgcaaatatc atagaacgta cttacacaaa tctagattag atggtatagc ttactacaga 440040 actaggatac atggtatagc ccgggtgctc ctaggttata aagctgtaca gcatgttact 440100 atactgaatg aatactgtaa gcaactgtaa caaagtgtaa gtatttatac atctaaacct 440160 agaaaaggta cagtgaaaat atggtggtat aatcttaaat gactattgtc aactatgatc 440220 tcgttgactg aaatgtcagc atgcggcaca tgactgtata accagacttc tcatcaaaaa 440280 caaatgctga aagaaaaaca catcaactaa ccaagaaaaa agaaacatat atgtccacac 440340 agagacttct ttttttacac aaatgttcat tgtacctttt tataatagct gggaactgaa 440400 aacagcctgg aactgaaaac agcccaggtg tcccttaaca gatgaagtca caaaccaccg 440460 aaacattcaa caatatggat gaatctcaaa aacattatgt tgagcaaaaa gaaacttttt 440520 acaacatata agtattgtat gactctactt acataaagtt ctgcgcaagc taaactaaga 440580 tgaaaacaat ctgaacaatg ttaggttcta ggggtggtgt ggggggaagg aataactagg 440640 aagaggtgta ggttctatac cctgatagaa ctttctggca aaggtgtata catttgtcac 440700 agctcatgaa atggtatatg tggtcaactg tattttccaa agatggtcac aatagaagcc 440760 attccacatg ctcttaacaa tgtaacactg tcattttttc atcaggtggt ggagtctatg 440820 gcccttctcc ttgaatctga gtgaaattag tgagtctttc aatccaaaga ctacagtcat 440880 acctcaacta tctacagagg actggttcca ggactcccat ggatcccaaa atccaaggat 440940 gcttcgaatc ccttatataa aatggcatgg tatttgcata taacctacat gcatcttcaa 441000 atatgttaaa ccatctctag attacttata ataccaaata caatgtaatg ctatgtaaac 441060 agttgttaca atgtattgtc aaagacaagc tctccttgcc aatccctgac caaatgagag 441120 attcatgagc aaaataaata gttgctgata tttaaggcac taagtttggg gcaatgtatt 441180 acacagcaat aaataactgg aacagcatag taaattctag ttaaaaatac taaactacta 441240 agttttagtt aacatacatg ctcaagttaa gggtgtggta tactaacaac tgcaacttac 441300 tttgaaaagc ataaaaaaag acactagaag aagacaggat ggatagatgg acaagataga 441360 agacaataac aaatagaaca aaatgttgtg aaattatatt ctacaattat tttaaagtct 441420 gtgtggtttg aaaaattgta cgataaaatg aagagtgaaa taaagacatt tccatacaaa 441480 caaaagctga aagattttgt agccagtaga cctatacttt agaaatgttt aagaaatttt 441540 ttcaagtaaa aggaaaataa caccagcaac aaacttggat ctacaaaaag gaatctccac 441600 aaagaaaaat aaataaaaat ggtaaatatg aaggtaaata taaaggaatg ttattcttag 441660 tttttaagtt tcttcgtaag acaactggcc tttgaaagaa atagtttcaa acgctgctgt 441720 ggaatctata acacatatag aagtaaaatg ttaagatcat aataccaaaa agaatgaggg 441780 agagtaaatg gatgtatact attccaaaat tcttacatta tacattaaga ggaataatat 441840 ttttgaaggt agattgaggt aagttaaagg tgcatattgt aaatcctaga agtatcactg 441900 gggggaaaaa aaacagaggg acaagctaat aatggagaca atacaaaatt ccaaaaatgc 441960 tccattaacc gaaaagaagg cagaaaagga agaaaagatt agacaaatag aaaacaaata 442020 gtgtcttaaa cacaattata ttgccaactg caataaatgt aaatggactt aatcaaaaag 442080 <210> 2916 <211> 1116 <212> DNA <213> Homo sapien <400> 2916 tggcatccag tccactttac catcagtgtt taaggaaacc atctctgata aggatgactg 60 aggaagagta ctctttggct tgttgacacc agcacagctg acacacccag atatctgttt 120 ggtctcctgt gaactttcaa ccaggattta aggatgccac tctggttaaa agctgaaaca 180 acttcaagga aacttcaggg aaaagagaag gcctggaatc tgatcctcca cttcagagaa 240 cagggagaaa aaagtgcatg tgaaatacta ctacttatcc atctcctggc tctgagcagt 300 acatgtcagg aacaagaggg aattgtagct ggaagacagt agaagagcca taggacaagt 360 ctctaagaga aggaagaaaa ggcgcaatga aagaaaacaa gtttaagata gtagaaaagc 420 attcaaagac ggcaacctga ggtggtggag tctatggccc ttctccttga atctgagtga 480 aattagtgag tctttcaatc caaagactac agtcatacct caactatcta cagaggactg 540 gttccaggac tcccatggat cccaaaatcc aaggatgctt cgaatccctt atataaaatg 600 gcatggtatt tgcatataac ctacatgcat cttcaaatat gttaaaccat ctctagatta 660 cttataatac caaatacaat gtaatgctat gtaaacagtt gttacaatgt attgtcaaag 720 acaagctctc cttgccaatc cctgaccaaa tgagagattc atgagcaaaa taaatagttg 780 ctgatattta aggcactaag tttggggcaa tgtattacac agcaataaat aactggaaca 840 gcatagtaaa ttctagttaa aaatactaaa ctactaagtt ttagttaaca tacatgctca 900 agttaagggt gtggtatact aacaactgca acttactttg aaaagcataa aaaaagacac 960 tagaagaaga caggatggat agatggacaa gatagaagac aataacaaat agaacaaaat 1020 gttgtgaaat tatattctac aattatttta aagtctgtgt ggtttgaaaa attgtacgat 1080 aaaatgaaga gtgaaataaa gacatttcca tacaaa 1116

Claims (89)

12 내지 30개의 연결된 뉴클레오사이드로 이루어진 변형된 올리고뉴클레오타이드를 포함하는 올리고머 화합물로서, 상기 변형된 올리고뉴클레오타이드의 핵염기 서열은 UBE3A-ATS RNA의 동일한 길이 부분과 적어도 90% 상보성이고, 상기 변형된 올리고뉴클레오타이드는 변형된 당 모이어티 및 변형된 뉴클레오사이드간 링키지(internucleoside linkage)로부터 선택된 적어도 하나의 변형을 포함하는, 올리고머 화합물.
변형된 올리고뉴클레오타이드를 포함하는 올리고머 화합물로서, 상기 변형된 올리고뉴클레오타이드는 12 내지 30개의 연결된 뉴클레오사이드로 이루어지고, 서열번호 17 내지 2762, 2786 내지 2863, 2872 내지 2904 중 어느 것의 적어도 12, 13, 14, 15, 16, 17, 18, 19 또는 20개의 인접한 핵염기를 포함하는 핵염기 서열을 갖는, 올리고머 화합물.
변형된 올리고뉴클레오타이드를 포함하는 올리고머 화합물로서, 상기 변형된 올리고뉴클레오타이드는 12 내지 30개의 연결된 뉴클레오사이드로 이루어지고, 서열번호 2763 내지 2785 또는 2864 내지 2871 중 어느 것의 적어도 12, 13, 14, 15, 16, 17 또는 18개의 인접한 핵염기를 포함하는 핵염기 서열을 갖는, 올리고머 화합물.
변형된 올리고뉴클레오타이드를 포함하는 올리고머 화합물로서, 상기 변형된 올리고뉴클레오타이드는 12 내지 30 연결된 뉴클레오사이드로 이루어지고,
서열번호 1의 핵염기 461,413 내지 461,487의 동일한 길이 부분;
서열번호 1의 핵염기 468,968 내지 469,013의 동일한 길이 부분; 또는
서열번호 1의 핵염기 483,965 내지 484,003의 동일한 길이 부분
과 상보성인 적어도 8, 적어도 9, 적어도 10, 적어도 11, 적어도 12, 적어도 13, 적어도 14, 적어도 15, 적어도 16, 적어도 17, 적어도 18, 적어도 19 또는 적어도 20개의 인접한 핵염기를 포함하는 핵염기 서열을 갖는, 올리고머 화합물.
변형된 올리고뉴클레오타이드를 포함하는 올리고머 화합물로서, 상기 변형된 올리고뉴클레오타이드는 12 내지 30개의 연결된 뉴클레오사이드로 이루어지고,
서열번호 1053, 1329, 1501, 1576, 1873, 1949, 2025, 2096, 2245, 2512, 2591, 2680 내지 2682 및 2844;
서열번호 376, 377, 2751 내지 2756, 2773 내지 2776, 2872, 2873, 2876 내지 2878; 또는
서열번호 172, 764 내지 770, 995, 1445, 1668, 1743, 2255, 2595, 2762 내지 2767
로부터 선택된 서열의 적어도 8, 적어도 9, 적어도 10, 적어도 11, 적어도 12, 적어도 13, 적어도 14, 적어도 15, 적어도 16, 적어도 17 또는 적어도 18개의 인접한 핵염기를 포함하는 핵염기 서열을 갖는, 올리고머 화합물.
제1항 내지 제5항 중 어느 한 항에 있어서, 상기 변형된 올리고뉴클레오타이드는 상기 변형된 올리고뉴클레오타이드의 전체 핵염기 서열에 걸쳐서 측정되는 경우 서열번호 1, 서열번호 2915 또는 서열번호 2916의 핵염기 서열과 적어도 80%, 85%, 90%, 95% 또는 100% 상보성인 핵염기 서열을 갖는, 올리고머 화합물.
제1항 내지 제6항 중 어느 한 항에 있어서, 상기 변형된 올리고뉴클레오타이드는 적어도 하나의 변형된 뉴클레오사이드를 포함하는, 올리고머 화합물.
제7항에 있어서, 상기 변형된 올리고뉴클레오타이드는 변형된 당 모이어티를 포함하는 적어도 하나의 변형된 뉴클레오사이드를 포함하는, 올리고머 화합물.
제8항에 있어서, 상기 변형된 올리고뉴클레오타이드는 이환식 당 모이어티를 포함하는 적어도 하나의 변형된 뉴클레오사이드를 포함하는, 올리고머 화합물.
제9항에 있어서, 상기 변형된 올리고뉴클레오타이드는 2'-4' 브리지를 갖는 이환식 당 모이어티를 포함하는 적어도 하나의 변형된 뉴클레오사이드를 포함하며, 상기 2'-4' 브리지는 -O-CH2-; 및 -O-CH(CH3)-로부터 선택되는, 올리고머 화합물.
제7항 내지 제10항 중 어느 한 항에 있어서, 상기 변형된 올리고뉴클레오타이드는 비-이환식 변형된 당 모이어티를 포함하는 적어도 하나의 변형된 뉴클레오사이드를 포함하는, 올리고머 화합물.
제11항에 있어서, 상기 비-이환식 변형된 당 모이어티는 2'-MOE 변형된 당 모이어티 또는 2'-OMe 변형된 당 모이어티인, 올리고머 화합물.
제7항 또는 제8항에 있어서, 상기 변형된 올리고뉴클레오타이드는 당 대용체(surrogate)를 포함하는 적어도 하나의 변형된 뉴클레오사이드를 포함하는, 올리고머 화합물.
제13항에 있어서, 상기 변형된 올리고뉴클레오타이드는 몰폴리노 및 PNA로부터 선택된 당 대용체를 포함하는 적어도 하나의 변형된 뉴클레오사이드를 포함하는, 올리고머 화합물.
제1항 내지 제8항 및 제11 내지 제14항 중 어느 한 항에 있어서, 상기 변형된 올리고뉴클레오타이드는 이환식 당 모이어티를 포함하지 않는, 올리고머 화합물.
제1항 내지 제15항 중 어느 한 항에 있어서, 상기 변형된 올리고뉴클레오타이드는 갭머(gapmer)인, 올리고머 화합물.
제1항 내지 제16항 중 어느 한 항에 있어서, 상기 변형된 올리고뉴클레오타이드는
1 내지 6개의 연결된 5'-영역 뉴클레오사이드로 이루어진 5'-영역;
6 내지 10개의 연결된 중심 영역 뉴클레오사이드로 이루어진 중심 영역; 및
1 내지 6개의 연결된 3'-영역 뉴클레오사이드로 이루어진 3'-영역
을 포함하는 당 모티프를 가지며;
상기 5'-영역 뉴클레오사이드 각각 및 상기 3'-영역 뉴클레오사이드 각각은 변형된 당 모이어티를 포함하고, 상기 중심 영역 뉴클레오사이드 각각은 2'-β-D-데옥시리보실 당 모이어티를 포함하는, 올리고머 화합물.
제17항에 있어서, 상기 변형된 올리고뉴클레오타이드는
5개의 연결된 5'-영역 뉴클레오사이드로 이루어진 5'-영역;
10개의 연결된 중심 영역 뉴클레오사이드로 이루어진 중심 영역; 및
5개의 연결된 3'-영역 뉴클레오사이드로 이루어진 3'-영역
을 가지며;
상기 5'-영역 뉴클레오사이드 각각 및 상기 3'-영역 뉴클레오사이드 각각은 2'-MOE 변형된 당 모이어티를 포함하고, 상기 중심 영역 뉴클레오사이드 각각은 2'-β-D-데옥시리보실 당 모이어티를 포함하는, 올리고머 화합물.
제17항에 있어서, 상기 변형된 올리고뉴클레오타이드는
4개의 연결된 5'-영역 뉴클레오사이드로 이루어진 5'-영역;
10개의 연결된 중심 영역 뉴클레오사이드로 이루어진 중심 영역; 및
6개의 연결된 3'-영역 뉴클레오사이드로 이루어진 3'-영역
을 가지며;
상기 5'-영역 뉴클레오사이드 각각 및 상기 3'-영역 뉴클레오사이드 각각은 2'-MOE 변형된 당 모이어티를 포함하고, 상기 중심 영역 뉴클레오사이드 각각은 2'-β-D-데옥시리보실 당 모이어티를 포함하는, 올리고머 화합물.
제17항에 있어서, 상기 변형된 올리고뉴클레오타이드는
6개의 연결된 5'-영역 뉴클레오사이드로 이루어진 5'-영역;
10개의 연결된 중심 영역 뉴클레오사이드로 이루어진 중심 영역; 및
4개의 연결된 3'-영역 뉴클레오사이드로 이루어진 3'-영역
을 가지며;
상기 5'-영역 뉴클레오사이드 각각 및 상기 3'-영역 뉴클레오사이드 각각은 2'-MOE 변형된 당 모이어티를 포함하고, 상기 중심 영역 뉴클레오사이드 각각은 2'-β-D-데옥시리보실 당 모이어티를 포함하는, 올리고머 화합물.
제17항에 있어서, 상기 변형된 올리고뉴클레오타이드는
5개의 연결된 5'-영역 뉴클레오사이드로 이루어진 5'-영역;
8개의 연결된 중심 영역 뉴클레오사이드로 이루어진 중심 영역; 및
5개의 연결된 3'-영역 뉴클레오사이드로 이루어진 3'-영역
을 가지며;
상기 5'-영역 뉴클레오사이드 각각 및 상기 3'-영역 뉴클레오사이드 각각은 2'-MOE 변형된 당 모이어티를 포함하고, 상기 중심 영역 뉴클레오사이드 각각은 2'-β-D-데옥시리보실 당 모이어티를 포함하는, 올리고머 화합물.
제17항에 있어서, 상기 변형된 올리고뉴클레오타이드는
4개의 연결된 5'-영역 뉴클레오사이드로 이루어진 5'-영역;
8개의 연결된 중심 영역 뉴클레오사이드로 이루어진 중심 영역; 및
6개의 연결된 3'-영역 뉴클레오사이드로 이루어진 3'-영역
을 가지며;
상기 5'-영역 뉴클레오사이드 각각 및 상기 3'-영역 뉴클레오사이드 각각은 2'-MOE 변형된 당 모이어티를 포함하고, 상기 중심 영역 뉴클레오사이드 각각은 2'-β-D-데옥시리보실 당 모이어티를 포함하는, 올리고머 화합물.
제17항에 있어서, 상기 변형된 올리고뉴클레오타이드는
4개의 연결된 5'-영역 뉴클레오사이드로 이루어진 5'-영역;
8개의 연결된 중심 영역 뉴클레오사이드로 이루어진 중심 영역; 및
6개의 연결된 3'-영역 뉴클레오사이드로 이루어진 3'-영역
을 가지며;
상기 5'-영역 뉴클레오사이드 각각 및 상기 3'-영역 뉴클레오사이드 각각은 2'-MOE 변형된 당 모이어티를 포함하고, 상기 중심 영역 뉴클레오사이드 각각은 2'-β-D-데옥시리보실 당 모이어티를 포함하는, 올리고머 화합물.
제1항 내지 제23항 중 어느 한 항에 있어서, 상기 변형된 올리고뉴클레오타이드는 적어도 하나의 변형된 뉴클레오사이드간 링키지를 포함하는, 올리고머 화합물.
제24항에 있어서, 상기 변형된 올리고뉴클레오타이드의 각각의 뉴클레오사이드간 링키지는 변형된 뉴클레오사이드간 링키지인, 올리고머 화합물.
제24항 또는 제25항에 있어서, 상기 변형된 뉴클레오사이드간 링키지는 포스포로티오에이트 뉴클레오사이드간 링키지인, 올리고머 화합물.
제24항 또는 제26항에 있어서, 상기 변형된 올리고뉴클레오타이드는 적어도 하나의 포스포다이에스터 뉴클레오사이드간 링키지를 포함하는, 올리고머 화합물.
제24항, 제26항 및 제27항 중 어느 한 항에 있어서, 뉴클레오사이드간 링키지 각각은 포스포다이에스터 뉴클레오사이드간 링키지 또는 포스포로티오에이트 뉴클레오사이드간 링키지로부터 독립적으로 선택되는, 올리고머 화합물.
제1항 내지 제24항, 제27항 및 제28항 중 어느 한 항에 있어서, 상기 변형된 올리고뉴클레오타이드는 soooossssssssssooss, sooooossssssssssoss, soooosssssssssoss, sooosssssssssooss, sooossssssssssoooss 또는 soosssssssssoooss로부터 선택된 뉴클레오사이드간 링키지 모티프를 가지며; s는 포스포로티오에이트 뉴클레오사이드간 링키지이고, o는 포스포다이에스터 뉴클레오사이드간 링키지인, 올리고머 화합물.
제1항 내지 제29항 중 어느 한 항에 있어서, 상기 변형된 올리고뉴클레오타이드는 변형된 핵염기를 포함하는, 올리고머 화합물.
제30항에 있어서, 상기 변형된 핵염기는 5-메틸 사이토신인, 올리고머 화합물.
제1항 내지 제31항 중 어느 한 항에 있어서, 상기 변형된 올리고뉴클레오타이드는 12 내지 30, 12 내지 22, 12 내지 20, 14 내지 18, 14 내지 20, 15 내지 17, 15 내지 25, 16 내지 20, 18 내지 22 또는 18 내지 20개의 연결된 뉴클레오사이드로 이루어지는, 올리고머 화합물.
제1항 내지 제32항 중 어느 한 항에 있어서, 상기 변형된 올리고뉴클레오타이드는 18개의 연결된 뉴클레오사이드로 이루어지는, 올리고머 화합물.
제1항, 제2항, 제4항 및 제6항 내지 제32항 중 어느 한 항에 있어서, 상기 변형된 올리고뉴클레오타이드는 20개의 연결된 뉴클레오사이드로 이루어지는, 올리고머 화합물.
제1항 내지 제34항 중 어느 한 항에 있어서, 상기 변형된 올리고뉴클레오타이드로 이루어진 올리고머 화합물.
제1항 내지 제34항 중 어느 한 항에 있어서, 접합체 모이어티 및 접합체 링커를 포함하는 접합체 기를 포함하는 올리고머 화합물.
제36항에 있어서, 상기 접합체 링커는 단일 결합으로 이루어진, 올리고머 화합물.
제36항에 있어서, 상기 접합체 링커는 절단 가능한, 올리고머 화합물.
제36항에 있어서, 상기 접합체 링커는 1 내지 3개의 링커-뉴클레오사이드를 포함하는, 올리고머 화합물.
제36항 내지 제39항 중 어느 한 항에 있어서, 상기 접합체 기는 상기 변형된 올리고뉴클레오타이드의 5'-단부에서 상기 변형된 올리고뉴클레오타이드에 부착되어 있는, 올리고머 화합물.
제36항 내지 제39항 중 어느 한 항에 있어서, 상기 접합체 기는 상기 변형된 올리고뉴클레오타이드의 3'-단부에서 상기 변형된 올리고뉴클레오타이드에 부착되어 있는, 올리고머 화합물.
제1항 내지 제34항 및 제36항 내지 제41항 중 어느 한 항에 있어서, 말단 기를 포함하는 올리고머 화합물.
제1항 내지 제42항 중 어느 한 항에 있어서, 상기 올리고머 화합물은 단일-가닥 올리고머 화합물인, 올리고머 화합물.
제1항 내지 제38항 및 제40항 내지 제43항 중 어느 한 항에 있어서, 상기 올리고머 화합물은 링커-뉴클레오사이드를 포함하지 않는, 올리고머 화합물.
제1항 내지 제42항 및 제44항 중 어느 한 항의 올리고머 화합물을 포함하는 올리고머 듀플렉스.
제1항 내지 제44항 중 어느 한 항의 올리고머 화합물 또는 제45항의 올리고머 듀플렉스를 포함하거나 또는 이들로 이루어진 안티센스 화합물.
제1항 내지 제44항 중 어느 한 항의 올리고머 화합물 또는 제45항의 올리고머 듀플렉스 및 약제학적으로 허용 가능한 담체 또는 희석제를 포함하는 약제학적 조성물.
제47항에 있어서, 상기 약제학적으로 허용 가능한 희석제는 인공 척수액인, 약제학적 조성물.
제48항에 있어서, 상기 약제학적 조성물은 상기 변형된 올리고뉴클레오타이드 및 인산염 완충 식염수로 본질적으로 이루어진, 약제학적 조성물.
대상체에게 제47항 내지 제50항 중 어느 한 항의 약제학적 조성물을 투여하는 단계를 포함하는 방법.
UBE3A-ATS와 연관된 질환의 치료 방법으로서, UBE3A-ATS와 연관된 질환을 갖거나 이의 발병 위험이 있는 개체에게 치료적 유효량의 제47항 내지 제49항 중 어느 한 항의 약제학적 조성물을 투여하는 단계; 및 이에 의해서 상기 UBE3A-ATS와 연관된 질환을 치료하는 단계를 포함하는, UBE3A-ATS와 연관된 질환의 치료 방법.
제51항에 있어서, 상기 UBE3A-ATS-연관 질환은 안젤만 증후군(Angelman Syndrome)인, UBE3A-ATS와 연관된 질환의 치료 방법.
제50항 내지 제52항 중 어느 한 항에 있어서, 상기 UBE3A-ATS-연관 질환의 적어도 하나의 증상 또는 특징이 개선되는, UBE3A-ATS와 연관된 질환의 치료 방법.
제53항에 있어서, 상기 증상 또는 특징은 발달 지연, 운동실조, 언어 장애, 수면 문제, 발작 또는 EEG 이상인, UBE3A-ATS와 연관된 질환의 치료 방법.
하기 화학식에 따른 변형된 올리고뉴클레오타이드 또는 이의 염:
Figure pct00211
.
하기 화학식에 따른 변형된 올리고뉴클레오타이드:
Figure pct00212
하기 화학식에 따른 변형된 올리고뉴클레오타이드 또는 이의 염:
Figure pct00213
.
하기 화학식에 따른 변형된 올리고뉴클레오타이드:
Figure pct00214
하기 화학식에 따른 변형된 올리고뉴클레오타이드 또는 이의 염:
Figure pct00215
.
하기 화학식에 상응하는 변형된 올리고뉴클레오타이드:
Figure pct00216
하기 화학식에 따른 변형된 올리고뉴클레오타이드 또는 이의 염:
Figure pct00217
.
하기 화학식에 따른 변형된 올리고뉴클레오타이드:
Figure pct00218
하기 화학식에 따른 변형된 올리고뉴클레오타이드 또는 이의 염:
Figure pct00219
.
하기 화학식에 따른 변형된 올리고뉴클레오타이드:
Figure pct00220
하기 화학식에 따른 변형된 올리고뉴클레오타이드 또는 이의 염:
Figure pct00221
.
하기 화학식에 따른 변형된 올리고뉴클레오타이드:
Figure pct00222
제55항, 제57항, 제59항, 제61항, 제63항 및 제65항 중 어느 한 항에 있어서, 나트륨염 또는 칼륨염인 변형된 올리고뉴클레오타이드.
제55항 내지 제67항 중 어느 한 항의 변형된 올리고뉴클레오타이드 및 약제학적으로 허용 가능한 담체 또는 희석제를 포함하는 약제학적 조성물.
제68항에 있어서, 상기 약제학적으로 허용 가능한 희석제는 인공 척수액인, 약제학적 조성물.
제69항에 있어서, 상기 약제학적 조성물은 상기 변형된 올리고뉴클레오타이드 및 인공 척수액으로 본질적으로 이루어진, 약제학적 조성물.
하기 화학적 표기에 따른 변형된 올리고뉴클레오타이드를 포함하는 화합물: mCesAeoTeo mCeoAeoTdsGdsAdsTds mCdsTdsTdsGdsGdsTdsAeoAeoGesGes mCe (서열번호 1949),
식 중,
A = 아데닌 핵염기이고,
mC = 5-메틸 사이토신 핵염기이며,
G = 구아닌 핵염기이고,
T = 티민 핵염기이며,
e = 2'-MOE 당 모이어티이고,
d = 2'-β-D-데옥시리보실 당 모이어티이고,
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고,
o = 포스포다이에스터 뉴클레오사이드간 링키지이다.
하기 화학적 표기에 따른 변형된 올리고뉴클레오타이드를 포함하는 화합물: Tes mCeoAeo mCeo mCeoAeoTdsTdsTdsTdsGdsAds mCds mCdsTdsTds mCeoTesTesAe (서열번호 2751),
식 중,
A = 아데닌 핵염기이고,
mC = 5-메틸 사이토신 핵염기이며,
G = 구아닌 핵염기이고,
T = 티민 핵염기이며,
e = 2'-MOE 당 모이어티이고,
d = 2'-β-D-데옥시리보실 당 모이어티이고,
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고,
o = 포스포다이에스터 뉴클레오사이드간 링키지이다.
하기 화학적 표기에 따른 변형된 올리고뉴클레오타이드를 포함하는 화합물: TesTeo mCeoAeo mCeo mCeoAdsTdsTdsTdsTdsGdsAds mCds mCdsTdsTeo mCesTesTe (서열번호 2752),
식 중,
A = 아데닌 핵염기이고,
mC = 5-메틸 사이토신 핵염기이며,
G = 구아닌 핵염기이고,
T = 티민 핵염기이며,
e = 2'-MOE 당 모이어티이고,
d = 2'-β-D-데옥시리보실 당 모이어티이고,
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고,
o = 포스포다이에스터 뉴클레오사이드간 링키지이다.
하기 화학적 표기에 따른 변형된 올리고뉴클레오타이드를 포함하는 화합물: Ges mCeoAeoTeoAeo mCeo mCds mCdsAdsGdsGdsGdsTdsAdsGdsGdsAeoTesTes mCe (서열번호 765),
식 중,
A = 아데닌 핵염기이고,
mC = 5-메틸 사이토신 핵염기이며,
G = 구아닌 핵염기이고,
T = 티민 핵염기이며,
e = 2'-MOE 당 모이어티이고,
d = 2'-β-D-데옥시리보실 당 모이어티이고,
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고,
o = 포스포다이에스터 뉴클레오사이드간 링키지이다.
하기 화학적 표기에 따른 변형된 올리고뉴클레오타이드를 포함하는 화합물: Aes mCeoGeo mCesAdsAdsTdsGdsTdsAdsTds mCdsAeoGeoGeo mCesAesAe (서열번호 2866),
식 중,
A = 아데닌 핵염기이고,
mC = 5-메틸 사이토신 핵염기이며,
G = 구아닌 핵염기이고,
T = 티민 핵염기이며,
e = 2'-MOE 당 모이어티이고,
d = 2'-β-D-데옥시리보실 당 모이어티이고,
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고,
o = 포스포다이에스터 뉴클레오사이드간 링키지이다.
하기 화학적 표기에 따른 변형된 올리고뉴클레오타이드를 포함하는 화합물: Aes mCeo mCeoAeoTeoTdsTdsTdsGdsAds mCds mCdsTdsTds mCdsTeoTeoAesGes mCe (서열번호 2873), 식 중,
A = 아데닌 핵염기이고,
mC = 5-메틸 사이토신 핵염기이며,
G = 구아닌 핵염기이고,
T = 티민 핵염기이며,
e = 2'-MOE 당 모이어티이고,
d = 2'-β-D-데옥시리보실 당 모이어티이고,
s = 포스포로티오에이트 뉴클레오사이드간 링키지이고,
o = 포스포다이에스터 뉴클레오사이드간 링키지이다.
제71항 내지 제76항 중 어느 한 항에 있어서, 접합체 기에 공유 연결된 상기 변형된 올리고뉴클레오타이드를 포함하는 화합물.
제71항 내지 제77항 중 어느 한 항의 약제학적 조성물 및 약제학적으로 허용 가능한 희석제 또는 담체를 포함하는 약제학적 조성물.
제78항에 있어서, 상기 약제학적으로 허용 가능한 희석제는 인공 척수액인, 약제학적 조성물.
제79항에 있어서, 상기 약제학적 조성물은 상기 변형된 올리고뉴클레오타이드 및 인공 척수액으로 본질적으로 이루어진, 약제학적 조성물.
제55항 내지 제67항 중 어느 한 항의 변형된 올리고뉴클레오타이드의 카이럴적으로 풍부한 집단으로서, 상기 집단은 특정 입체화학 배위를 갖는 적어도 하나의 특정 포스포로티오에이트 뉴클레오사이드간 링키지를 포함하는 변형된 올리고뉴클레오타이드가 풍부한, 카이럴적으로 풍부한 집단.
제81항에 있어서, 상기 집단은 (Sp) 배위를 갖는 적어도 하나의 특정 포스포로티오에이트 뉴클레오사이드간 링키지를 포함하는 변형된 올리고뉴클레오타이드가 풍부한, 카이럴적으로 풍부한 집단.
제81항에 있어서, 상기 집단은 (Rp) 배위를 갖는 적어도 하나의 특정 포스포로티오에이트 뉴클레오사이드간 링키지를 포함하는 변형된 올리고뉴클레오타이드가 풍부한, 카이럴적으로 풍부한 집단.
제81항에 있어서, 상기 집단은 각각의 포스포로티오에이트 뉴클레오사이드간 링키지에서 독립적으로 선택된 특정 입체화학 배위를 갖는 변형된 올리고뉴클레오타이드가 풍부한, 카이럴적으로 풍부한 집단.
제84항에 있어서, 상기 집단은 각각의 포스포로티오에이트 뉴클레오사이드간 링키지에서 (Sp) 배위를 갖는 변형된 올리고뉴클레오타이드가 풍부한, 카이럴적으로 풍부한 집단.
제84항에 있어서, 상기 집단은 각각의 포스포로티오에이트 뉴클레오사이드간 링키지에서 (Rp) 배위를 갖는 변형된 올리고뉴클레오타이드가 풍부한, 카이럴적으로 풍부한 집단.
제84항에 있어서, 상기 집단은 하나의 특정 포스포로티오에이트 뉴클레오사이드간 링키지에서 (Rp) 배위를 갖고, 나머지 포스포로티오에이트 뉴클레오사이드간 링키지 각각에서 (Sp) 배위를 갖는 변형된 올리고뉴클레오타이드가 풍부한, 카이럴적으로 풍부한 집단.
제81항 또는 제84항에 있어서, 상기 집단은 5'에서 3' 방향으로, Sp, Sp, 및 Rp 배위의 적어도 3개의 인접한 포스포로티오에이트 뉴클레오사이드간 링키지를 갖는 변형된 올리고뉴클레오타이드가 풍부한, 카이럴적으로 풍부한 집단.
제55항 내지 제67항 중 어느 한 항의 변형된 올리고뉴클레오타이드의 카이럴적으로 풍부한 집단으로서, 상기 변형된 올리고뉴클레오타이드의 상기 포스포로티오에이트 뉴클레오사이드간 링키지 모두는 입체무작위인, 카이럴적으로 풍부한 집단.
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