JP5944313B2 - 特定の化学物質、組成物および方法 - Google Patents

特定の化学物質、組成物および方法 Download PDF

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JP5944313B2
JP5944313B2 JP2012520630A JP2012520630A JP5944313B2 JP 5944313 B2 JP5944313 B2 JP 5944313B2 JP 2012520630 A JP2012520630 A JP 2012520630A JP 2012520630 A JP2012520630 A JP 2012520630A JP 5944313 B2 JP5944313 B2 JP 5944313B2
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compound
cancer
formula
substituted
acid
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JP2012533541A5 (hr
JP2012533541A (ja
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ピンダ レン，
ピンダ レン，
イー リュー，
イー リュー，
トロイ エドワード ウィルソン，
トロイ エドワード ウィルソン，
リャンシェン リー，
リャンシェン リー，
カトリーナ チャン，
カトリーナ チャン，
クリスチャン ロメル，
クリスチャン ロメル，
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インテリカイン， エルエルシー
インテリカイン， エルエルシー
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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JP2012520630A 2009-07-15 2010-07-15 特定の化学物質、組成物および方法 Active JP5944313B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/503,776 2009-07-15
US12/503,776 US8193182B2 (en) 2008-01-04 2009-07-15 Substituted isoquinolin-1(2H)-ones, and methods of use thereof
PCT/US2010/002020 WO2011008302A1 (en) 2009-07-15 2010-07-15 Certain chemical entities, compositions and methods

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JP2016103832A Division JP6158395B2 (ja) 2009-07-15 2016-05-25 特定の化学物質、組成物および方法

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JP2012533541A JP2012533541A (ja) 2012-12-27
JP2012533541A5 JP2012533541A5 (hr) 2016-03-17
JP5944313B2 true JP5944313B2 (ja) 2016-07-05

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US (12) US8193182B2 (hr)
EP (4) EP2456444B1 (hr)
JP (2) JP5944313B2 (hr)
KR (1) KR101680406B1 (hr)
CN (3) CN102711767B (hr)
AU (1) AU2010274075B2 (hr)
BR (1) BR112012000968B8 (hr)
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RU2582676C2 (ru) 2016-04-27
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AU2010274075B2 (en) 2015-01-22
FIC20210039I1 (fi) 2021-11-03
RU2012105071A (ru) 2013-08-20
KR20120097479A (ko) 2012-09-04
SI2456444T1 (sl) 2015-07-31
IL243932A (en) 2016-11-30
US20180098983A1 (en) 2018-04-12
US8569323B2 (en) 2013-10-29
EP2918589B1 (en) 2016-11-02
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US20190290636A1 (en) 2019-09-26
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US8785456B2 (en) 2014-07-22
CN109912599A (zh) 2019-06-21
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SG10201503886WA (en) 2015-06-29
MY168762A (en) 2018-12-04
US20090312319A1 (en) 2009-12-17
PT2456444E (pt) 2015-06-09
RU2582676C3 (ru) 2022-01-17
CA2768307C (en) 2018-02-13
US20120149701A1 (en) 2012-06-14
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EP2456444B1 (en) 2015-03-18
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US20140341894A1 (en) 2014-11-20
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CN106188059B (zh) 2019-02-01
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NL301140I1 (hr) 2021-11-03
AU2010274075A1 (en) 2012-02-09
US20220265637A1 (en) 2022-08-25
BR112012000968B8 (pt) 2021-05-25
HUS2100048I1 (hu) 2021-12-28
EP2456444A4 (en) 2012-12-05
MX2012000626A (es) 2012-03-26
NZ706506A (en) 2016-11-25
MY175979A (en) 2020-07-19
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UA109878C2 (uk) 2015-10-26
CN106188059A (zh) 2016-12-07
RU2746319C2 (ru) 2021-04-12
BR112012000968A2 (pt) 2017-12-05
PL2456444T3 (pl) 2015-08-31
SMT201500141B (it) 2015-09-07
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