PL3442535T3 - Związki heterocykliczne jako inhibitory kinazy ret - Google Patents

Związki heterocykliczne jako inhibitory kinazy ret

Info

Publication number
PL3442535T3
PL3442535T3 PL17719688.8T PL17719688T PL3442535T3 PL 3442535 T3 PL3442535 T3 PL 3442535T3 PL 17719688 T PL17719688 T PL 17719688T PL 3442535 T3 PL3442535 T3 PL 3442535T3
Authority
PL
Poland
Prior art keywords
kinase inhibitors
heterocyclic compounds
ret kinase
ret
heterocyclic
Prior art date
Application number
PL17719688.8T
Other languages
English (en)
Inventor
Allan Jordan
Rebecca NEWTON
Bohdan Waszkowycz
Jonathan Mark Sutton
George Hynd
Silvia PAOLETTA
Euan Alexander Fraser Fordyce
Original Assignee
Cancer Research Technology Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Research Technology Limited filed Critical Cancer Research Technology Limited
Publication of PL3442535T3 publication Critical patent/PL3442535T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
PL17719688.8T 2016-04-15 2017-04-18 Związki heterocykliczne jako inhibitory kinazy ret PL3442535T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB201606635 2016-04-15
PCT/GB2017/051077 WO2017178845A1 (en) 2016-04-15 2017-04-18 Heterocyclic compounds as ret kinase inhibitors

Publications (1)

Publication Number Publication Date
PL3442535T3 true PL3442535T3 (pl) 2022-10-24

Family

ID=58633036

Family Applications (1)

Application Number Title Priority Date Filing Date
PL17719688.8T PL3442535T3 (pl) 2016-04-15 2017-04-18 Związki heterocykliczne jako inhibitory kinazy ret

Country Status (13)

Country Link
US (3) US10844067B2 (pl)
EP (2) EP3442535B1 (pl)
DK (1) DK3442535T3 (pl)
ES (1) ES2925698T3 (pl)
HR (1) HRP20221051T8 (pl)
HU (1) HUE060082T2 (pl)
LT (1) LT3442535T (pl)
PL (1) PL3442535T3 (pl)
PT (1) PT3442535T (pl)
RS (1) RS63609B1 (pl)
SI (1) SI3442535T1 (pl)
SM (1) SMT202200348T1 (pl)
WO (1) WO2017178845A1 (pl)

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TWI876442B (zh) 2017-10-10 2025-03-11 美商絡速藥業公司 6-(2-羥基-2-甲基丙氧基)-4-(6-(6-((6-甲氧基吡啶-3-基)甲基)-3,6-二氮雜雙環[3.1.1]庚-3-基)吡啶-3-基)吡唑并[1,5-a]吡啶-3-甲腈之調配物
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Also Published As

Publication number Publication date
HRP20221051T8 (hr) 2023-07-21
LT3442535T (lt) 2022-10-25
ES2925698T3 (es) 2022-10-19
EP3442535B1 (en) 2022-06-01
US20210047334A1 (en) 2021-02-18
EP4104837A2 (en) 2022-12-21
HUE060082T2 (hu) 2023-01-28
PT3442535T (pt) 2022-09-05
US20190263819A1 (en) 2019-08-29
RS63609B1 (sr) 2022-10-31
HRP20221051T1 (hr) 2023-03-03
US11661423B2 (en) 2023-05-30
SMT202200348T1 (it) 2022-11-18
WO2017178845A1 (en) 2017-10-19
EP4104837A3 (en) 2023-04-26
DK3442535T3 (da) 2022-09-05
US20240116938A1 (en) 2024-04-11
EP3442535A1 (en) 2019-02-20
SI3442535T1 (sl) 2023-01-31
US10844067B2 (en) 2020-11-24

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