HUE060082T2 - Heterociklusos vegyületek, mint RET kináz inhibitorok - Google Patents

Heterociklusos vegyületek, mint RET kináz inhibitorok

Info

Publication number
HUE060082T2
HUE060082T2 HUE17719688A HUE17719688A HUE060082T2 HU E060082 T2 HUE060082 T2 HU E060082T2 HU E17719688 A HUE17719688 A HU E17719688A HU E17719688 A HUE17719688 A HU E17719688A HU E060082 T2 HUE060082 T2 HU E060082T2
Authority
HU
Hungary
Prior art keywords
kinase inhibitors
heterocyclic compounds
ret kinase
ret
heterocyclic
Prior art date
Application number
HUE17719688A
Other languages
English (en)
Inventor
Allan Jordan
Rebecca Newton
Bohdan Waszkowycz
Jonathan Sutton
George Hynd
Silvia Paoletta
Euan Alexander Fraser Fordyce
Original Assignee
Cancer Research Tech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Research Tech Ltd filed Critical Cancer Research Tech Ltd
Publication of HUE060082T2 publication Critical patent/HUE060082T2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
HUE17719688A 2016-04-15 2017-04-18 Heterociklusos vegyületek, mint RET kináz inhibitorok HUE060082T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB201606635 2016-04-15

Publications (1)

Publication Number Publication Date
HUE060082T2 true HUE060082T2 (hu) 2023-01-28

Family

ID=58633036

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE17719688A HUE060082T2 (hu) 2016-04-15 2017-04-18 Heterociklusos vegyületek, mint RET kináz inhibitorok

Country Status (12)

Country Link
US (3) US10844067B2 (hu)
EP (2) EP4104837A3 (hu)
DK (1) DK3442535T3 (hu)
ES (1) ES2925698T3 (hu)
HR (1) HRP20221051T8 (hu)
HU (1) HUE060082T2 (hu)
LT (1) LT3442535T (hu)
PL (1) PL3442535T3 (hu)
PT (1) PT3442535T (hu)
RS (1) RS63609B1 (hu)
SI (1) SI3442535T1 (hu)
WO (1) WO2017178845A1 (hu)

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CA3096043A1 (en) 2018-04-03 2019-10-10 Blueprint Medicines Corporation Ret inhibitor for use in treating cancer having a ret alteration
JP2022500383A (ja) 2018-09-10 2022-01-04 アレイ バイオファーマ インコーポレイテッド Ｒｅｔキナーゼ阻害剤としての縮合複素環式化合物
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Also Published As

Publication number Publication date
US20190263819A1 (en) 2019-08-29
US11661423B2 (en) 2023-05-30
US20210047334A1 (en) 2021-02-18
PT3442535T (pt) 2022-09-05
EP3442535A1 (en) 2019-02-20
ES2925698T3 (es) 2022-10-19
LT3442535T (lt) 2022-10-25
EP4104837A3 (en) 2023-04-26
HRP20221051T1 (hr) 2023-03-03
US10844067B2 (en) 2020-11-24
HRP20221051T8 (hr) 2023-07-21
WO2017178845A1 (en) 2017-10-19
US20240116938A1 (en) 2024-04-11
EP4104837A2 (en) 2022-12-21
DK3442535T3 (da) 2022-09-05
PL3442535T3 (pl) 2022-10-24
EP3442535B1 (en) 2022-06-01
RS63609B1 (sr) 2022-10-31
SI3442535T1 (sl) 2023-01-31

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