HRP20110707T1 - C-met modulatori i postupci uporabe - Google Patents
C-met modulatori i postupci uporabe Download PDFInfo
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- HRP20110707T1 HRP20110707T1 HR20110707T HRP20110707T HRP20110707T1 HR P20110707 T1 HRP20110707 T1 HR P20110707T1 HR 20110707 T HR20110707 T HR 20110707T HR P20110707 T HRP20110707 T HR P20110707T HR P20110707 T1 HRP20110707 T1 HR P20110707T1
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- 150000001875 compounds Chemical class 0.000 claims abstract 16
- 150000003839 salts Chemical class 0.000 claims abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 26
- 201000010099 disease Diseases 0.000 claims 13
- 208000035475 disorder Diseases 0.000 claims 13
- 239000008194 pharmaceutical composition Substances 0.000 claims 13
- 230000002159 abnormal effect Effects 0.000 claims 2
- 230000001413 cellular effect Effects 0.000 claims 2
- 208000003174 Brain Neoplasms Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 208000000461 Esophageal Neoplasms Diseases 0.000 claims 1
- 208000008839 Kidney Neoplasms Diseases 0.000 claims 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 206010038389 Renal cancer Diseases 0.000 claims 1
- 208000000453 Skin Neoplasms Diseases 0.000 claims 1
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 201000004101 esophageal cancer Diseases 0.000 claims 1
- 206010017758 gastric cancer Diseases 0.000 claims 1
- 201000010982 kidney cancer Diseases 0.000 claims 1
- 201000007270 liver cancer Diseases 0.000 claims 1
- 208000014018 liver neoplasm Diseases 0.000 claims 1
- 201000005202 lung cancer Diseases 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 201000000849 skin cancer Diseases 0.000 claims 1
- 201000011549 stomach cancer Diseases 0.000 claims 1
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- C—CHEMISTRY; METALLURGY
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- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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HR20110707T HRP20110707T1 (hr) | 2003-09-26 | 2011-10-05 | C-met modulatori i postupci uporabe |
HR20110810T HRP20110810T1 (hr) | 2003-09-26 | 2011-11-02 | N-[3-fluoro-4-({6-(metiloksi)-7[(3-morfolin-4-ilpropil)oksi]kinolin-4-il}oksi)fenil]-n'-(4-fluorofenil)ciklopropan-1,1-dikarboksamid za liječenje raka |
HRP20140012TT HRP20140012T1 (hr) | 2003-09-26 | 2014-01-07 | C-met modulatori i postupci uporabe |
HRP20140563TT HRP20140563T1 (hr) | 2003-09-26 | 2014-06-13 | C-met modulatori i postupci uporabe |
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HR20110810T HRP20110810T1 (hr) | 2003-09-26 | 2011-11-02 | N-[3-fluoro-4-({6-(metiloksi)-7[(3-morfolin-4-ilpropil)oksi]kinolin-4-il}oksi)fenil]-n'-(4-fluorofenil)ciklopropan-1,1-dikarboksamid za liječenje raka |
HRP20140012TT HRP20140012T1 (hr) | 2003-09-26 | 2014-01-07 | C-met modulatori i postupci uporabe |
HRP20140563TT HRP20140563T1 (hr) | 2003-09-26 | 2014-06-13 | C-met modulatori i postupci uporabe |
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