MX2008011220A - Compuestos de pirazol heterobiciclicos y metodos de uso. - Google Patents
Compuestos de pirazol heterobiciclicos y metodos de uso.Info
- Publication number
- MX2008011220A MX2008011220A MX2008011220A MX2008011220A MX2008011220A MX 2008011220 A MX2008011220 A MX 2008011220A MX 2008011220 A MX2008011220 A MX 2008011220A MX 2008011220 A MX2008011220 A MX 2008011220A MX 2008011220 A MX2008011220 A MX 2008011220A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- compounds
- pyrazole compounds
- tautomers
- solvates
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
Se describen compuestos de las fórmulas (Ia) y (Ib) (ver fórmulas (Ia) y (Ib)) y estereoisómeros, isómeros geométricos, tautómeros, solvatos, metabolitos y sales farmacéuticamente aceptables de los mismos son útiles para inhibir el receptor de tirosina cinasa y para tratar trastornos mediados por los mismos. Los métodos para usar los compuestos de la fórmula Ia y Ib, y estereoisómeros, isómeros geométricos, tautómeros, solvatos y sales farmacéuticamente aceptables de los mismos, por diagnósticos in vitro, in situ e in vivo, prevención o tratamiento de tales trastornos en células mamíferas o condiciones patológicas asociadas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77980506P | 2006-03-07 | 2006-03-07 | |
US87483206P | 2006-12-14 | 2006-12-14 | |
PCT/US2007/005583 WO2007103308A2 (en) | 2006-03-07 | 2007-03-06 | Heterobicyclic pyrazole compounds and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2008011220A true MX2008011220A (es) | 2008-09-11 |
Family
ID=38475465
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2008011220A MX2008011220A (es) | 2006-03-07 | 2007-03-06 | Compuestos de pirazol heterobiciclicos y metodos de uso. |
Country Status (20)
Country | Link |
---|---|
US (2) | US7723330B2 (es) |
EP (1) | EP2001880A2 (es) |
JP (1) | JP2009529047A (es) |
KR (1) | KR20080110783A (es) |
AR (1) | AR059887A1 (es) |
AU (1) | AU2007224020A1 (es) |
BR (1) | BRPI0708615A2 (es) |
CA (1) | CA2645137A1 (es) |
CL (1) | CL2007000601A1 (es) |
CO (1) | CO6140061A2 (es) |
CR (1) | CR10338A (es) |
EC (1) | ECSP088791A (es) |
IL (1) | IL193587A0 (es) |
MA (1) | MA31339B1 (es) |
MX (1) | MX2008011220A (es) |
NO (1) | NO20084183L (es) |
RU (1) | RU2008139599A (es) |
TW (1) | TW200800996A (es) |
WO (1) | WO2007103308A2 (es) |
ZA (1) | ZA200807632B (es) |
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- 2007-03-06 EP EP07752297A patent/EP2001880A2/en not_active Withdrawn
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- 2007-03-06 RU RU2008139599/04A patent/RU2008139599A/ru not_active Application Discontinuation
- 2007-03-06 AU AU2007224020A patent/AU2007224020A1/en not_active Abandoned
- 2007-03-06 CA CA002645137A patent/CA2645137A1/en not_active Abandoned
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- 2007-03-07 CL CL2007000601A patent/CL2007000601A1/es unknown
- 2007-03-07 TW TW096107890A patent/TW200800996A/zh unknown
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CA2645137A1 (en) | 2007-09-13 |
CR10338A (es) | 2008-10-31 |
BRPI0708615A2 (pt) | 2011-06-07 |
MA31339B1 (fr) | 2010-05-03 |
AR059887A1 (es) | 2008-05-07 |
ZA200807632B (en) | 2011-04-28 |
JP2009529047A (ja) | 2009-08-13 |
NO20084183L (no) | 2008-11-24 |
CO6140061A2 (es) | 2010-03-19 |
WO2007103308A2 (en) | 2007-09-13 |
TW200800996A (en) | 2008-01-01 |
US7723330B2 (en) | 2010-05-25 |
EP2001880A2 (en) | 2008-12-17 |
ECSP088791A (es) | 2008-11-27 |
RU2008139599A (ru) | 2010-04-20 |
KR20080110783A (ko) | 2008-12-19 |
US20070238726A1 (en) | 2007-10-11 |
CL2007000601A1 (es) | 2008-01-25 |
AU2007224020A1 (en) | 2007-09-13 |
IL193587A0 (en) | 2009-08-03 |
WO2007103308A3 (en) | 2008-02-07 |
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