PT2213661E - Moduladores de c-met e métodos de uso - Google Patents

Moduladores de c-met e métodos de uso Download PDF

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Publication number
PT2213661E
PT2213661E PT10160518T PT10160518T PT2213661E PT 2213661 E PT2213661 E PT 2213661E PT 10160518 T PT10160518 T PT 10160518T PT 10160518 T PT10160518 T PT 10160518T PT 2213661 E PT2213661 E PT 2213661E
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PT
Portugal
Prior art keywords
optionally substituted
compound
oxy
methyloxy
fluorophenyl
Prior art date
Application number
PT10160518T
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English (en)
Portuguese (pt)
Inventor
John M Nuss
Wei Xu
Lynne Canne Bannen
Diva Sze-Ming Chan
Timothy Patrick Forsyth
Richard George Khoury
James William Leahy
Morrison B Mac
Larry W Mann
Jason Jevious Parks
Yong Wang
Original Assignee
Exelixis Inc
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34397024&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2213661(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Exelixis Inc filed Critical Exelixis Inc
Publication of PT2213661E publication Critical patent/PT2213661E/pt

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
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    • A61K31/47—Quinolines; Isoquinolines
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