PL2183254T3 - Inhibitory aktywności białkowej kinazy tyrozynowej - Google Patents

Inhibitory aktywności białkowej kinazy tyrozynowej

Info

Publication number
PL2183254T3
PL2183254T3 PL08800252T PL08800252T PL2183254T3 PL 2183254 T3 PL2183254 T3 PL 2183254T3 PL 08800252 T PL08800252 T PL 08800252T PL 08800252 T PL08800252 T PL 08800252T PL 2183254 T3 PL2183254 T3 PL 2183254T3
Authority
PL
Poland
Prior art keywords
inhibitors
tyrosine kinase
kinase activity
protein tyrosine
protein
Prior art date
Application number
PL08800252T
Other languages
English (en)
Inventor
Stephen William Claridge
Ljubomir Isakovic
Michael Mannion
Stéphane Raeppel
Oscar Mario Saavedra
Frédéric Gaudette
Lijie Zhan
Nancy Z Zhou
Franck Raeppel
ROBERT DéZIEL
Arkadii Vaisburg
Tetsuyuki Uno
Original Assignee
Methylgene Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Methylgene Inc filed Critical Methylgene Inc
Publication of PL2183254T3 publication Critical patent/PL2183254T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
PL08800252T 2007-08-29 2008-08-28 Inhibitory aktywności białkowej kinazy tyrozynowej PL2183254T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96867307P 2007-08-29 2007-08-29
PCT/CA2008/001538 WO2009026717A1 (en) 2007-08-29 2008-08-28 Inhibitors of protein tyrosine kinase activity
EP08800252.2A EP2183254B1 (en) 2007-08-29 2008-08-28 Inhibitors of protein tyrosine kinase activity

Publications (1)

Publication Number Publication Date
PL2183254T3 true PL2183254T3 (pl) 2017-10-31

Family

ID=40386626

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08800252T PL2183254T3 (pl) 2007-08-29 2008-08-28 Inhibitory aktywności białkowej kinazy tyrozynowej

Country Status (19)

Country Link
US (3) US8404846B2 (pl)
EP (1) EP2183254B1 (pl)
JP (1) JP5656634B2 (pl)
KR (1) KR101556269B1 (pl)
CN (3) CN101932586A (pl)
AR (1) AR068066A1 (pl)
AU (1) AU2008293038B2 (pl)
BR (1) BRPI0816064B8 (pl)
CA (1) CA2697795C (pl)
DK (1) DK2183254T3 (pl)
ES (1) ES2635131T3 (pl)
IL (1) IL204192A (pl)
MX (1) MX2010002427A (pl)
MY (1) MY156536A (pl)
PL (1) PL2183254T3 (pl)
RU (1) RU2495044C2 (pl)
TW (1) TWI571468B (pl)
WO (1) WO2009026717A1 (pl)
ZA (1) ZA201001512B (pl)

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US10180422B1 (en) 2017-08-22 2019-01-15 Scripps Health Methods of treating a neuroendocrine tumor
CN111225662B (zh) 2017-10-17 2022-11-22 伊尼塔公司 药物组合物和剂型
US11447500B2 (en) 2018-03-08 2022-09-20 Wellmarker Bio Co., Ltd. Thienopyridine derivatives and pharmaceutical composition comprising same
BR112020023746A2 (pt) 2018-05-23 2021-02-17 Beigene, Ltd. anticorpo, composição farmacêutica, método para tratar câncer, ácido nucleico isolado, vetor, célula hospedeira, processo para a produção de um anticorpo e reagente de diagnóstico
CN109384799B (zh) * 2018-11-12 2020-07-14 深圳海王医药科技研究院有限公司 一种多靶点激酶抑制剂化合物的晶型a及制备方法和含有其的药物组合物
US20230172914A1 (en) 2019-09-06 2023-06-08 Wellmarker Bio Co., Ltd. Biomarker-based therapeutic composition
JP2022546861A (ja) * 2019-09-10 2022-11-09 ミラティ セラピューティクス， インコーポレイテッド マルチチロシンキナーゼ阻害剤の結晶形、調製方法およびその使用
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CN114945576B (zh) * 2020-01-07 2023-10-13 南京明德新药研发有限公司 氘代噻吩并吡啶类化合物
TW202302597A (zh) * 2021-03-10 2023-01-16 美商米拉蒂醫療公司 多重酪胺酸激酶抑制劑之結晶鹽、其製備方法及用途
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Also Published As

Publication number Publication date
ZA201001512B (en) 2010-11-24
CN109970759A (zh) 2019-07-05
US8846927B2 (en) 2014-09-30
US8404846B2 (en) 2013-03-26
RU2495044C2 (ru) 2013-10-10
WO2009026717A1 (en) 2009-03-05
CA2697795C (en) 2016-08-16
BRPI0816064B1 (pt) 2020-01-28
CN105777776A (zh) 2016-07-20
KR20100075873A (ko) 2010-07-05
DK2183254T3 (en) 2017-09-11
EP2183254A1 (en) 2010-05-12
MY156536A (en) 2016-02-26
AR068066A1 (es) 2009-11-04
JP2010536887A (ja) 2010-12-02
CN101932586A (zh) 2010-12-29
TW200914458A (en) 2009-04-01
BRPI0816064B8 (pt) 2021-05-25
CA2697795A1 (en) 2009-03-05
EP2183254A4 (en) 2011-09-28
US20090264440A1 (en) 2009-10-22
IL204192A (en) 2016-08-31
BRPI0816064A2 (pt) 2015-03-31
TWI571468B (zh) 2017-02-21
KR101556269B1 (ko) 2015-09-30
AU2008293038B2 (en) 2013-08-29
US20120108628A1 (en) 2012-05-03
ES2635131T3 (es) 2017-10-02
MX2010002427A (es) 2010-03-30
EP2183254B1 (en) 2017-06-21
RU2010111729A (ru) 2011-10-10
CN105777776B (zh) 2021-06-08
JP5656634B2 (ja) 2015-01-21
AU2008293038A1 (en) 2009-03-05
US20130165477A1 (en) 2013-06-27
US8389541B2 (en) 2013-03-05

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