MX2012000626A - Determinadas entidades, composiciones y métodos químicos. - Google Patents

Determinadas entidades, composiciones y métodos químicos.

Info

Publication number
MX2012000626A
MX2012000626A MX2012000626A MX2012000626A MX2012000626A MX 2012000626 A MX2012000626 A MX 2012000626A MX 2012000626 A MX2012000626 A MX 2012000626A MX 2012000626 A MX2012000626 A MX 2012000626A MX 2012000626 A MX2012000626 A MX 2012000626A
Authority
MX
Mexico
Prior art keywords
chemical entities
methods
compositions
certain chemical
kinase activity
Prior art date
Application number
MX2012000626A
Other languages
English (en)
Spanish (es)
Inventor
Pingda Ren
Yi Liu
Troy Edward Wilson
Liansheng Li
Katrina Chan
Christian Rommel
Original Assignee
Intellikine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intellikine Inc filed Critical Intellikine Inc
Publication of MX2012000626A publication Critical patent/MX2012000626A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/36—Sulfur atom
    • C07D473/38—Sulfur atom attached in position 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
MX2012000626A 2009-07-15 2010-07-15 Determinadas entidades, composiciones y métodos químicos. MX2012000626A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/503,776 US8193182B2 (en) 2008-01-04 2009-07-15 Substituted isoquinolin-1(2H)-ones, and methods of use thereof
PCT/US2010/002020 WO2011008302A1 (en) 2009-07-15 2010-07-15 Certain chemical entities, compositions and methods

Publications (1)

Publication Number Publication Date
MX2012000626A true MX2012000626A (es) 2012-03-26

Family

ID=43450336

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2012000626A MX2012000626A (es) 2009-07-15 2010-07-15 Determinadas entidades, composiciones y métodos químicos.
MX2017012418A MX379814B (es) 2009-07-15 2010-07-15 Proceso para preparar compuestos de dihidroisoquinolinas-fenil-purinas.
MX2013010738A MX351028B (es) 2009-07-15 2012-01-12 Determinadadas entidades, composiciones y metodos quimicos.

Family Applications After (2)

Application Number Title Priority Date Filing Date
MX2017012418A MX379814B (es) 2009-07-15 2010-07-15 Proceso para preparar compuestos de dihidroisoquinolinas-fenil-purinas.
MX2013010738A MX351028B (es) 2009-07-15 2012-01-12 Determinadadas entidades, composiciones y metodos quimicos.

Country Status (33)

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US (13) US8193182B2 (index.php)
EP (4) EP2918589B1 (index.php)
JP (2) JP5944313B2 (index.php)
KR (1) KR101680406B1 (index.php)
CN (3) CN106188059B (index.php)
AU (1) AU2010274075B2 (index.php)
BR (1) BR112012000968B8 (index.php)
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DK (1) DK2456444T3 (index.php)
ES (1) ES2538853T3 (index.php)
FI (1) FIC20210039I1 (index.php)
HR (1) HRP20150586T1 (index.php)
HU (1) HUS2100048I1 (index.php)
IL (2) IL217181A (index.php)
IN (1) IN2012DN00943A (index.php)
LT (1) LTC2456444I2 (index.php)
LU (1) LUC00237I2 (index.php)
MX (3) MX2012000626A (index.php)
MY (2) MY168762A (index.php)
NL (1) NL301140I2 (index.php)
NO (1) NO2021047I1 (index.php)
NZ (3) NZ706506A (index.php)
PH (2) PH12015502432A1 (index.php)
PL (1) PL2456444T3 (index.php)
PT (1) PT2456444E (index.php)
RU (2) RU2746319C2 (index.php)
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PH12020550450A1 (en) 2021-06-07
JP2016210781A (ja) 2016-12-15
MX379814B (es) 2025-03-11
RU2582676C2 (ru) 2016-04-27
CA2768307A1 (en) 2011-01-20
MX351028B (es) 2017-09-28
RU2746319C2 (ru) 2021-04-12
US20200222384A1 (en) 2020-07-16
HRP20150586T1 (hr) 2015-07-03
JP6158395B2 (ja) 2017-07-05

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