JPH0421818B2 - - Google Patents

Info

Publication number
JPH0421818B2
JPH0421818B2 JP56122347A JP12234781A JPH0421818B2 JP H0421818 B2 JPH0421818 B2 JP H0421818B2 JP 56122347 A JP56122347 A JP 56122347A JP 12234781 A JP12234781 A JP 12234781A JP H0421818 B2 JPH0421818 B2 JP H0421818B2
Authority
JP
Japan
Prior art keywords
antibody
labeled
antigenic substance
antigen
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP56122347A
Other languages
English (en)
Japanese (ja)
Other versions
JPS57118159A (en
Inventor
Gary Samuel David
Howard Edward Greene
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HYBRITCEH Inc
Original Assignee
HYBRITCEH Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22639055&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPH0421818(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by HYBRITCEH Inc filed Critical HYBRITCEH Inc
Publication of JPS57118159A publication Critical patent/JPS57118159A/ja
Publication of JPH0421818B2 publication Critical patent/JPH0421818B2/ja
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
    • G01N2470/04—Sandwich assay format
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/971—Capture of complex after antigen-antibody reaction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP56122347A 1980-08-04 1981-08-04 Immunological inhibition test using signle coulomb- oriented antibody Granted JPS57118159A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/175,133 US4376110A (en) 1980-08-04 1980-08-04 Immunometric assays using monoclonal antibodies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP3324583A Division JPH0587816A (ja) 1980-08-04 1991-12-09 イムノメトリツクアツセイ法および当該方法用の試薬キツト

Publications (2)

Publication Number Publication Date
JPS57118159A JPS57118159A (en) 1982-07-22
JPH0421818B2 true JPH0421818B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1992-04-14

Family

ID=22639055

Family Applications (2)

Application Number Title Priority Date Filing Date
JP56122347A Granted JPS57118159A (en) 1980-08-04 1981-08-04 Immunological inhibition test using signle coulomb- oriented antibody
JP3324583A Pending JPH0587816A (ja) 1980-08-04 1991-12-09 イムノメトリツクアツセイ法および当該方法用の試薬キツト

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP3324583A Pending JPH0587816A (ja) 1980-08-04 1991-12-09 イムノメトリツクアツセイ法および当該方法用の試薬キツト

Country Status (5)

Country Link
US (1) US4376110A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (2) JPS57118159A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE889855A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1281640C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1225944B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (1551)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840588A (en) * 1971-05-20 1998-11-24 Strahilevitz; Meir Agglutination inhibition assay methods and reagents for psychoactive substances
EP0146654A3 (en) * 1980-06-20 1986-08-20 Unilever Plc Processes and apparatus for carrying out specific binding assays
US6406920B1 (en) 1980-06-20 2002-06-18 Inverness Medical Switzerland Gmbh Processes and apparatus for carrying out specific binding assays
JPS57501147A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1980-07-16 1982-07-01
NL185309C (nl) * 1980-07-28 1990-03-01 Akzo Nv Methode voor het bepalen van antigenen met behulp van twee of meer monoklonale antilichamen alsmede immuunreagens.
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4879219A (en) * 1980-09-19 1989-11-07 General Hospital Corporation Immunoassay utilizing monoclonal high affinity IgM antibodies
EP0064063B1 (en) * 1980-11-07 1985-09-11 Celltech Limited Assay for interferon
US4837167A (en) * 1981-01-30 1989-06-06 Centocor, Inc. Immunoassay for multi-determinant antigens using high-affinity
US4680258A (en) * 1981-03-24 1987-07-14 Sloan-Kettering Institute For Cancer Research Process for sex determination in man by use of monoclonal antibodies to the H-Y antigen
JPS585659A (ja) * 1981-06-24 1983-01-13 ハイブリテツク　インコ−ポレ−テツド 単クロ−ン性抗体を使用する免疫学的、抑制試験
US4474893A (en) * 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
EP0072902B1 (de) * 1981-08-21 1985-04-24 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Bestimmung von carcinoembryonalem Antigen (CEA) und zur Bestimmung geeignete Antikörperlösung
US4661586A (en) * 1981-11-17 1987-04-28 The Board Of Trustees Of The Leland Stanford Junior University Monoclonal anti-idiotype antibodies
EP0082636B2 (en) * 1981-12-11 2006-10-18 The Welsh National School of Medicine Luminescent labelling materials and procedures
USRE32011E (en) * 1981-12-14 1985-10-22 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4444878A (en) * 1981-12-21 1984-04-24 Boston Biomedical Research Institute, Inc. Bispecific antibody determinants
ES521370A0 (es) * 1982-04-12 1985-04-16 Hybritech Inc Un procedimiento para obtener un polidoma.
US4483929A (en) * 1982-05-03 1984-11-20 Liposome Technology Incorporated Liposomes with glycolipid-linked antibodies
US4514505A (en) * 1982-05-21 1985-04-30 The Trustees Of Columbia University In The City Of New York Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays
US4792528A (en) * 1982-05-21 1988-12-20 The Trustees Of Columbia University In The City Of New York Methods for obtaining monoclonal antibodies useful in enhanced sensitivity immunoassays
US4443427A (en) * 1982-06-21 1984-04-17 Sidney Farber Cancer Institute, Inc. Monoclonal antibody
US4623621A (en) * 1982-06-24 1986-11-18 Hoffmann-La Roche Inc. Immunoassay for peptide and protein oligomers
DE3225027A1 (de) * 1982-07-05 1984-01-05 Boehringer Mannheim Gmbh, 6800 Mannheim Immunchemisches messverfahren
US4471058A (en) * 1982-07-26 1984-09-11 Board Of Trustees Operating Michigan State University Method for the detection and/or determination of a polyvalent antigen using at least two different monoclonal antibodies
US4879218A (en) * 1982-09-13 1989-11-07 Virginia Tech Intellectual Properties, Inc. Antibody for C.difficile
JPS5954966A (ja) * 1982-09-22 1984-03-29 Mochida Pharmaceut Co Ltd 免疫学的測定試薬
US4596771A (en) * 1982-09-27 1986-06-24 Research Corporation Monoclonal antibodies to vitamin B-6 and immunossay method
US4659678A (en) * 1982-09-29 1987-04-21 Serono Diagnostics Limited Immunoassay of antigens
US4845027B1 (en) * 1982-10-13 1994-05-10 Biowhittaker Inc Fluorometric assay of allergic reactions
US4844966A (en) * 1982-10-13 1989-07-04 Minnesota Mining And Manufacturing Company Assaying total IgE levels with fluorogenic enzyme labeled antibody
US4539292A (en) * 1982-12-29 1985-09-03 Reid Michael J Immunoassay technique for specific immunoglobulin E
US4818709A (en) * 1983-01-21 1989-04-04 Primus Frederick J CEA-family antigens, Anti-CEA antibodies and CEA immunoassay
WO1984002983A1 (en) * 1983-01-21 1984-08-02 Frederick James Primus Specific cea-family antigens, antibodies specific thereto and their methods of use
US4525452A (en) * 1983-01-24 1985-06-25 Btc Diagnostics Limited Partnership Enzyme immunoassay with step of immersing sample in deionized water
US4994373A (en) 1983-01-27 1991-02-19 Enzo Biochem, Inc. Method and structures employing chemically-labelled polynucleotide probes
US4849337A (en) * 1983-01-31 1989-07-18 Minnesota Mining And Manufacturing Company Assaying allergen specific IgE levels with fluorogenic enzyme labeled antibody
US4558006A (en) * 1983-02-04 1985-12-10 Kirin-Amgen, Inc. A.T.C.C. HB8209 and its monoclonal antibody to erythropoietin
US5106760A (en) * 1983-02-04 1992-04-21 Kirin-Amgen ATCC HB8209, its monoclonal antibody to erythropoietin and assay using same
US4474892A (en) * 1983-02-16 1984-10-02 Board Of Trustees Of The Leland Stanford Junior University Two-site immunoassays using monoclonal antibodies of different classes or subclasses and test kits for performing same
FR2541304A1 (fr) * 1983-02-21 1984-08-24 Centre Nat Rech Scient Anticorps monoclonaux anti-legionella, procede d'obtention et application au diagnostic de pneumonies
US5084379A (en) * 1983-04-29 1992-01-28 Biowhittaker, Inc. Fluorometric assay of chymopapain hypersensitivity and reagents therefor
US4851356A (en) * 1983-05-06 1989-07-25 The Trustees Of Columbia University In The City Of New York Immunoassay for human chorionic gonadotropin
JPS60501271A (ja) * 1983-05-06 1985-08-08 ザ・トラステイ−ズ・オブ・コロンビア・ユニヴア−シテイ・イン・ザ・シテイ・オブ・ニユ−・ヨ−ク ヒト絨毛性ゴナドトロピンのイムノアツセイ
US4642284A (en) * 1983-06-13 1987-02-10 Scripps Clinic And Research Foundation Method and system for detection of complement pathway activation
GB8317124D0 (en) * 1983-06-23 1983-07-27 Ekins R P Free ligand assay
USRE34405E (en) * 1983-08-01 1993-10-12 Abbott Laboratories Determination of analytes in particle-containing medium
EP0154625A4 (en) * 1983-08-18 1987-09-02 Quidel HYBRIDOME CELL LINE PRODUCING AN ALLERGY SUPPRESSOR FACTOR.
US4828981A (en) * 1983-08-24 1989-05-09 Synbiotics Corporation Immunoassays for determining Dirofilaria immitis infection using antiidiotype monoclonal antibody reagents
JPS6060557A (ja) * 1983-09-13 1985-04-08 Eisai Co Ltd Ｐｉｖｋａ−２の測定方法および試薬
JPS6080768A (ja) * 1983-10-12 1985-05-08 Eisai Co Ltd 塩基性胎児蛋白の測定方法および試薬
US4595661A (en) * 1983-11-18 1986-06-17 Beckman Instruments, Inc. Immunoassays and kits for use therein which include low affinity antibodies for reducing the hook effect
US5229272A (en) * 1989-04-25 1993-07-20 Igen, Inc. Catalytic antibody components
US6846654B1 (en) 1983-11-29 2005-01-25 Igen International, Inc. Catalytic antibodies as chemical sensors
US6057121A (en) * 1983-11-29 2000-05-02 Igen International, Inc. Method of catalyzing stereochemical reactions
US4839275A (en) * 1983-12-01 1989-06-13 The Jewish Hospital Circulating antigens of dirofilaria immitis, monoclonal antibodies specific therefor and methods of preparing such antibodies and detecting such antigens
US4683196A (en) * 1983-12-12 1987-07-28 Meru, Inc. Method and materials for the identification of lipopolysaccharide producing microorganisms
EP0168422A1 (en) * 1983-12-12 1986-01-22 Meru, Inc. Method and materials for the identification of lipopolysaccharide producing microorganisms
US4610960A (en) * 1983-12-21 1986-09-09 Wisconsin Alumni Research Foundation Monoclonal antibody to thrombospondin and method for assaying for and isolating thrombospondin
US4666865A (en) * 1984-01-13 1987-05-19 Centocor, Inc. Immunoassay for biologically active human interferon-gamma employing unique monoclonal antibodies
US4757001A (en) * 1984-02-16 1988-07-12 Fujirebio Kabushiki Kaisha Method of measuring biological ligand by utilizing amylase
GB8404368D0 (en) * 1984-02-20 1984-03-28 Cogent Ltd Monoclonal antibodies to human cytomegalovirus
US4865997A (en) * 1984-02-23 1989-09-12 Becton Dickinson And Company Assay for ligands by separating bound and free tracer from sample
US4690890A (en) * 1984-04-04 1987-09-01 Cetus Corporation Process for simultaneously detecting multiple antigens using dual sandwich immunometric assay
US4780401A (en) * 1984-04-09 1988-10-25 Ciba-Geigy Corporation Novel monoclonal antibodies to human renin and hybridoma cells, processes for their preparation and their applications
US5011771A (en) * 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
GR850899B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1984-04-12 1985-11-25 Gen Hospital Corp
CA1260372A (en) * 1984-04-27 1989-09-26 Elazar Rabbani Hybridization method for the detection of genetic materials
US4632901A (en) * 1984-05-11 1986-12-30 Hybritech Incorporated Method and apparatus for immunoassays
ZA853756B (en) * 1984-06-01 1986-01-29 Miles Lab Nucleic acid hybridization assay employing immobilized rna probes
US4731326A (en) * 1984-06-04 1988-03-15 Ortho Diagnostic Systems Inc. Disease diagnosis by detection of shed normal tissue antigens
US4636478A (en) * 1984-07-16 1987-01-13 Becton, Dickinson And Company Monoclonal antibodies recognizing L-thyroxine
EP0188603A1 (en) * 1984-08-01 1986-07-30 Advanced Biotechnology Associates, Inc. A salmonella-specific analyses reagent
US4707438A (en) * 1984-08-22 1987-11-17 Tel Aviv University Immunoassay for breast cancer employing monoclonal antibodies
IL76184A0 (en) * 1984-08-28 1985-12-31 Hybritech Inc Article for diagnostic assays
US4745075A (en) * 1984-09-06 1988-05-17 Burroughs Wellcome Co. Diagnostic test methods
EP0198826A4 (en) * 1984-10-29 1989-03-23 Eks Inc IMMUNOTEST PROCEDURE FOR SMALL MOLECULES.
JPS62500686A (ja) * 1984-10-31 1987-03-19 アルコン　ラボラトリ−ズ　インコ−ポレイテツド 抗原の定性試験、製品および方法
US4713347A (en) * 1985-01-14 1987-12-15 Sensor Diagnostics, Inc. Measurement of ligand/anti-ligand interactions using bulk conductance
JPH0672893B2 (ja) * 1985-08-16 1994-09-14 富士薬品工業株式会社 ヒト血中のヒトプロリルヒドロキシラーゼの放射性免疫学的測定法による定量法
DE3508384A1 (de) * 1985-03-08 1986-11-06 Boehringer Mannheim Gmbh, 6800 Mannheim Hemmung humaner speichel- und pankreasamylase durch monoklonale antikoerper
DE3509958A1 (de) * 1985-03-20 1986-09-25 Bayer Ag, 5090 Leverkusen Monoklonale antikoerper gegen atriale, natriuretische peptide vom menschen
US4722889A (en) * 1985-04-02 1988-02-02 Leeco Diagnostics, Inc. Immunoassays using multiple monoclonal antibodies and scavenger antibodies
US4707443A (en) * 1985-04-19 1987-11-17 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Soluble interleukin-2 receptor as a disease indicator and a method of assaying the same
US4935339A (en) * 1985-05-07 1990-06-19 Nichols Institute Diagnostics Delayed solid phase immunologic assay
US4737456A (en) * 1985-05-09 1988-04-12 Syntex (U.S.A.) Inc. Reducing interference in ligand-receptor binding assays
US5273882A (en) * 1985-06-13 1993-12-28 Amgen Method and kit for performing nucleic acid hybridization assays
US4931385A (en) * 1985-06-24 1990-06-05 Hygeia Sciences, Incorporated Enzyme immunoassays and immunologic reagents
US5112738A (en) * 1985-07-03 1992-05-12 Miles Inc. Histamine derivatives, immunogen conjugates and antibodies raised thereto
US4910133A (en) * 1985-08-29 1990-03-20 Ube Industries, Limited Diagnostic test drug comprising monoclonal antibody to human copper.zinc-superoxide dismutase and diagnostic test method using the same
US5063151A (en) * 1985-09-20 1991-11-05 Biometallics, Inc. Immunoassay method and kit
US5595908A (en) * 1985-09-26 1997-01-21 University Of Southern Mississipi Piezoelectric device for detection of polynucleotide hybridization
US4933275A (en) * 1985-10-24 1990-06-12 The General Hospital Corporation Method for the detection of a polypeptide subunit in the presence of a quaternary protein containing the subunit
US6265176B1 (en) 1985-10-29 2001-07-24 Cordis Corporation Dot immunoassay on plastic sheets
US4770993A (en) * 1985-10-31 1988-09-13 Beatrice Companies, Inc. Hybridoma tumor cell lines and their monoclonal antibodies to thaumatin
US5501949A (en) * 1985-12-10 1996-03-26 Murex Diagnostics Corporation Particle bound binding component immunoassay
US4868108A (en) * 1985-12-12 1989-09-19 Hygeia Sciences, Incorporated Multiple-antibody detection of antigen
US4810639A (en) * 1985-12-20 1989-03-07 E. I. Du Pont De Nemours And Company Immunoassay for CK-MB using bound and soluble antibodies
US4772551A (en) * 1985-12-26 1988-09-20 Neogen Corporation Method and test kit for detecting a trichothecene using novel monoclonal antibodies
US5175113A (en) * 1986-01-16 1992-12-29 Novo Nordisk A/S Modified β2 -microglobulin
US4741999A (en) * 1986-02-26 1988-05-03 The Research Foundation Of State University Of New York Monoclonal antibodies useful in the identification of microorganisms causing periodontal disease
JPS62231168A (ja) 1986-03-21 1987-10-09 ハイブリテツク・インコ−ポレイテツド アナライト−レセプタ−分析用内部標準を設けるための改良法
AU7202887A (en) * 1986-03-26 1987-10-20 Murex Corp. Device and method for determining microbial resistance to antimicrobic agents
US5426029A (en) * 1986-03-31 1995-06-20 T Cell Diagnostics, Inc. Therapeutic and diagnostic methods using leukocyte surface antigens
US5292636A (en) * 1986-03-31 1994-03-08 T Cell Diagnostics, Inc. Therapeutic and diagnostic methods using soluble T cell surface molecules
US5006459A (en) * 1986-03-31 1991-04-09 T Cell Sciences, Inc. Therapeutic and diagnostic methods using soluble T cell surface molecules
US6881536B1 (en) * 1986-04-30 2005-04-19 Bioveris Corporation Particle based electrochemiluminescent assays
US4963355A (en) * 1986-06-23 1990-10-16 Igen, Inc. Production of antibody catalysts
US5120504A (en) * 1986-07-14 1992-06-09 Hybritech Incorporated Apparatus for immunoassays with vent chennels in the container side wall
DE3751182T2 (de) * 1986-08-06 1995-10-26 Scripps Clinic Res Monoklonale Antikörper, B-spezifisch für Apolipoprotein, die von zwei Hybridomen erzeugt werden.
US4935343A (en) * 1986-08-08 1990-06-19 Syntex (U.S.A.) Inc. Monoclonal antibodies for interleukin-1β
US5316914A (en) * 1986-09-04 1994-05-31 Fuji Yakuhin Kogyo Kabushiki Kaisha Method for determining human collagen peptides by way of enzyme immunoassay
JP2617299B2 (ja) * 1986-09-17 1997-06-04 ダイナボット 株式会社 エラスターゼ１の免疫学的測定方法
US5763262A (en) * 1986-09-18 1998-06-09 Quidel Corporation Immunodiagnostic device
US20010023075A1 (en) * 1992-04-03 2001-09-20 Siu-Yin Wong A immunodiagnositc device having a dessicant incorporated therein
US4828986A (en) * 1986-09-29 1989-05-09 Scripps Clinic And Research Foundation Assay method and diagnostic system for determining the ratio of APO B-100 to APO A-I in a blood sample
US4804626A (en) * 1986-10-22 1989-02-14 The General Hospital Corporation Immunometric assay for the detection of human chorionic gonadotropin
US4911909A (en) * 1987-01-02 1990-03-27 E. I. Du Pont De Nemours And Company Method of controlling hypertension using monoclonal antibodies to angiotensin-II
US4940659A (en) * 1987-02-20 1990-07-10 Monoclonetics International, Inc. Screening extra-cellular body fluids for superoxide dismutase (SOD-1) for determining fetal trisomy 21 down syndrome
US5789235A (en) * 1987-03-23 1998-08-04 Tackett; Scott E. Modifying cell metabolism via extra-cellular nucleases
DE3714147A1 (de) * 1987-04-28 1988-11-17 Boehringer Mannheim Gmbh Immunchemisches verfahren und reagenz zur bestimmung eines polyvalenten antigens in einer fluessigen probe
US4788138A (en) * 1987-04-30 1988-11-29 Beckman Instruments, Inc. Method to achieve a linear standard curve in a sandwich immunoassay
US5474899A (en) * 1987-05-13 1995-12-12 Cistron Biotechnology, Inc. Selective immunoassay for IL-1 β
US5149626A (en) * 1987-05-14 1992-09-22 Mclean Hospital Corporation Multiple antigen immunoassay
FR2615622B1 (fr) * 1987-05-19 1994-05-06 Ire Medgenix Sa Dosage plasmatique de monokines
US4971904A (en) * 1987-06-26 1990-11-20 E. I. Du Pont De Nemours And Company Heterogeneous immunoassay
US5009998A (en) * 1987-06-26 1991-04-23 E. I. Du Pont De Nemours And Company Method for performing heterogeneous immunoassay
US5179000A (en) * 1987-07-24 1993-01-12 Nippon Kayaku Kabushiki Kaisha Method for assaying basic fetoprotein in urine and assay kit therefor
US5447837A (en) * 1987-08-05 1995-09-05 Calypte, Inc. Multi-immunoassay diagnostic system for antigens or antibodies or both
DE3889041T2 (de) * 1987-09-02 1994-10-27 Igen Inc Herstellung von Immunonähe-Katalysatoren.
US6461825B1 (en) * 1987-09-30 2002-10-08 Sanofi (Societe Anonyme) Immunometric assay kit and method applicable to whole cells
US4859612A (en) * 1987-10-07 1989-08-22 Hygeia Sciences, Inc. Metal sol capture immunoassay procedure, kit for use therewith and captured metal containing composite
DE3734015A1 (de) * 1987-10-08 1989-04-20 Behringwerke Ag Diagnostisches mittel und verfahren zur bestimmung von apolipoprotein b
US5231000A (en) * 1987-10-08 1993-07-27 The Mclean Hospital Antibodies to A4 amyloid peptide
US5217869A (en) * 1987-10-13 1993-06-08 Terrapin Technologies, Inc. Method to produce immunodiagnostic reagents
US5300425A (en) * 1987-10-13 1994-04-05 Terrapin Technologies, Inc. Method to produce immunodiagnostic reagents
US5256372A (en) * 1987-11-06 1993-10-26 Idexx Corporation Dipstick test device including a removable filter assembly
US5094941A (en) * 1987-12-31 1992-03-10 Zymogenetics, Inc. Monoclonal antibodies to PDGF
US4891313A (en) * 1988-01-21 1990-01-02 Boehringer Manheim Corporation Method for determination of a component of a sample
WO1989009393A1 (en) * 1988-03-24 1989-10-05 Igen, Inc. Luminescent chimeric proteins
US5202267A (en) * 1988-04-04 1993-04-13 Hygeia Sciences, Inc. Sol capture immunoassay kit and procedure
US6702705B1 (en) 1988-05-04 2004-03-09 Igen International, Inc. Prodrugs activated by targeted catalytic proteins
US5620845A (en) * 1988-06-06 1997-04-15 Ampcor, Inc. Immunoassay diagnostic kit
US5173399A (en) * 1988-06-10 1992-12-22 Abbott Laboratories Mouse monoclonal antibodies to hiv-1p24 and their use in diagnostic tests
AU2684488A (en) 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
CA1335880C (en) * 1988-07-14 1995-06-13 Thomas P. O'connor Detection of an antibody and antigen in an immunoassay
US5096809A (en) * 1988-07-25 1992-03-17 Pacific Biotech, Inc. Whole blood assays using porous membrane support devices
US5059522A (en) * 1988-08-18 1991-10-22 Wayne Lawrence G Intrinsic enzyme dot blot immunoassay or indentification of microorganisms
US5030555A (en) * 1988-09-12 1991-07-09 University Of Florida Membrane-strip reagent serodiagnostic apparatus and method
DE3836348A1 (de) * 1988-10-25 1990-04-26 Boehringer Mannheim Gmbh Verfahren zur bestimmung von fuer ein antigen klassenspezifischen antikoerpern und dazu geeignetes reagenz
EP0368674A3 (en) * 1988-11-11 1991-10-09 SANYO CHEMICAL INDUSTRIES, Ltd. Immunoassay and test kits therefor
US5200051A (en) * 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
US6306594B1 (en) 1988-11-14 2001-10-23 I-Stat Corporation Methods for microdispensing patterened layers
US5322838A (en) * 1988-11-16 1994-06-21 Brigham & Women's Hospital Use of INHIB (the C3 β-chain) in the detection and inhibition of inflammation
US5512657A (en) * 1988-12-12 1996-04-30 Bainbridge Sciences, Inc. Detection of complexes which include basement membrane components as diagnostic of cancer and other diseases
US5264370A (en) * 1988-12-12 1993-11-23 Bainbridge Laboratories, Inc. Detection of basement membrane components as diagnostic of cancer and other diseases
CA2008304C (en) * 1989-01-31 2001-03-27 Craig S. Hill Assay for bone alkaline phosphatase
AU649949B2 (en) * 1989-02-03 1994-06-09 Commonwealth Scientific And Industrial Research Organisation Monoclonal antibodies directed against vitronectin and fibronectin, and uses thereof
US5106761A (en) * 1989-03-13 1992-04-21 International Canine Genetics, Inc. Method for detecting molecules in a liquid medium
US5599538A (en) * 1989-04-25 1997-02-04 Igen, Inc. Autoantibodies which enhance the rate of a chemical reaction
US6048717A (en) * 1989-04-25 2000-04-11 Igen International, Inc. Inhibitors of catalytic antibodies
US5194585A (en) * 1989-04-25 1993-03-16 Igen, Inc. Inhibitors of catalytic antibodies
US5236836A (en) * 1989-04-25 1993-08-17 Igen, Inc. Autoantibodies which enhance the rate of a chemical reaction
US5658753A (en) * 1989-04-25 1997-08-19 Paul; Sudhir Catalytic antibody components
US5318897A (en) * 1989-04-25 1994-06-07 Igen, Inc. Monoclonal antibody and antibody components elicited to a polypeptide antigen ground state
US6258360B1 (en) 1989-05-04 2001-07-10 Igen International, Inc. Prodrugs activated by targeted catalytic proteins
ATE130099T1 (de) * 1989-06-02 1995-11-15 Univ Georgetown Verfahren zum nachweis von antikörpern gegen streptokinase.
JPH05504617A (ja) * 1989-06-06 1993-07-15 アンプコー・インコーポレーテッド 免疫検定診断用キット
US5187068A (en) * 1989-06-09 1993-02-16 Nicolae Luca Method for determination of lipid moiety and apolipoprotein expressed epitope immunoreactivity on intact lipoprotein
US5484735A (en) * 1989-08-23 1996-01-16 Northwestern University Immunoassay of glycosylated proteins employing antibody directed to reductively glycosylated N-terminal amino acids
US6008057A (en) * 1989-08-25 1999-12-28 Roche Diagnostics Corporation Immunoassay system
US5830709A (en) * 1989-10-27 1998-11-03 Benson; Roger E. Detection method for homologous portions of a class of substances
US5196311A (en) * 1989-10-27 1993-03-23 Health Research, Incorporated Elisa test for von willebrand factor
US5202264A (en) * 1989-10-27 1993-04-13 Health Research, Incorporated ELISA using multi-species antibodies for detection of von Willebrand factor in multiple species
DE69024659T2 (de) * 1989-11-03 1996-11-07 Donald L Morton Harnwegstumor-assoziiertes antigen, verwendung von antigenen untereinheiten und nachweisverfahren
US5624898A (en) 1989-12-05 1997-04-29 Ramsey Foundation Method for administering neurologic agents to the brain
US6407061B1 (en) 1989-12-05 2002-06-18 Chiron Corporation Method for administering insulin-like growth factor to the brain
US5196324A (en) * 1989-12-15 1993-03-23 Eli Lilly And Company Monoclonal antibodies reactive with a human atheroma associated antigen
KR910014706A (ko) * 1990-01-10 1991-08-31 원본미기재 세척이 필요없는 개량된 이뮤노어세이(immunoassay)장치
ES2070492T3 (es) * 1990-01-26 1995-06-01 Washington Res Found Reactividad inmunitaria para oncogenes expresados activos para diagnostico y tratamiento de estados malignos.
US6190885B1 (en) 1990-02-02 2001-02-20 Cancer Research Fund Of Contra Costa Fusion protein containing HMFG Epitop E (S)
US5532135A (en) * 1990-02-02 1996-07-02 Cancer Research Fund Of Contra Costa Solid-phase competitive assay utilizing a fusion protein
WO1991012333A1 (en) * 1990-02-07 1991-08-22 Kanebo, Ltd. Antiprocollagenase monoclonal antibody and assay of procollagenase therewith
US5096837A (en) * 1990-02-08 1992-03-17 Pacific Biotech, Inc. Immunochromatographic assay and method of using same
US5922615A (en) 1990-03-12 1999-07-13 Biosite Diagnostics Incorporated Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
US5223220A (en) * 1990-03-27 1993-06-29 Pacific Biotech, Inc. Solid phase immunoassay device and method of making same
CA2095642C (en) * 1990-08-02 1999-12-14 Howard C. Krivan Adhesion receptors for pathogenic or opportunistic microorganisms
WO1992005282A1 (en) * 1990-09-14 1992-04-02 Biosite Diagnostics, Inc. Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
JPH085920B2 (ja) * 1991-01-21 1996-01-24 富士薬品工業株式会社 抗ヒトストロムライシンモノクローナル抗体及び酵素免疫測定法
US5997878A (en) 1991-03-07 1999-12-07 Connaught Laboratories Recombinant poxvirus-cytomegalovirus, compositions and uses
AU657102B2 (en) * 1991-04-12 1995-03-02 Bio-Rad Laboratories, Inc. CA 195-like immunoreactive antigen from human amniotic fluid
US5223396A (en) * 1991-05-03 1993-06-29 Boehringer Ingelheim Pharmaceuticals, Inc. Method for detecting organ transplant rejection
WO1992020820A1 (en) * 1991-05-15 1992-11-26 Vanderbilt University Method to determine metastatic potential of tumor cells
US5998220A (en) 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
US5877028A (en) 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
US5869345A (en) * 1991-05-29 1999-02-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing conductive barrier
US5468648A (en) * 1991-05-29 1995-11-21 Smithkline Diagnostics, Inc. Interrupted-flow assay device
US5607863A (en) * 1991-05-29 1997-03-04 Smithkline Diagnostics, Inc. Barrier-controlled assay device
US6168956B1 (en) 1991-05-29 2001-01-02 Beckman Coulter, Inc. Multiple component chromatographic assay device
WO1992022668A1 (en) * 1991-06-14 1992-12-23 Vanderbilt University Method and compositions to assess oxidative stress in vivo
US5338660A (en) * 1991-07-12 1994-08-16 Board Of Supervisors Of Louisiana State University And Agricutural And Mechanical College Diagnosis of Fasciola infections by detection of antigens in feces or intestinal content
US5965379A (en) * 1991-07-19 1999-10-12 Cytimmune Sciences Inc. Method for measuring endogenous cytokines
ATE184703T1 (de) * 1991-07-19 1999-10-15 Cytimmune Sciences Inc Verfahren und testsatz zur messung von endogenen zytokinen
US5726010A (en) * 1991-07-31 1998-03-10 Idexx Laboratories, Inc. Reversible flow chromatographic binding assay
US6007999A (en) * 1991-07-31 1999-12-28 Idexx Laboratories, Inc. Reversible flow chromatographic binding assay
US5369006A (en) * 1991-08-20 1994-11-29 E. I. Du Pont De Nemours And Company Determination of CK isoenzymes and CK isoforms
CA2116453A1 (en) 1991-08-28 1993-03-18 Basil Rapoport Disease associated human autoantibodies specific for human thyroid peroxidase
DE4134297A1 (de) * 1991-10-17 1993-04-22 Behringwerke Ag Monoclonale antikoerper gegen mycoplasma pneumoniae, diese produzierende hybridome, verfahren zu deren herstellung sowie deren verwendung
DK0625048T4 (da) * 1991-10-23 2006-02-20 Fibrogen Inc Syntese af human procollagener og collagener i rekombinant DNA-systemer
WO1993008473A1 (en) * 1991-10-24 1993-04-29 Beth Israel Hospital Association Assay for malignant effusions
US5525461A (en) * 1991-11-01 1996-06-11 T Cell Diagnostics, Inc. Therapeutic and diagnostic methods using total leukocyte surface antigens
WO1993014404A1 (en) * 1992-01-17 1993-07-22 Selective Antibodies Limited Determination of haptens
ES2090835T3 (es) * 1992-02-17 1996-10-16 Akzo Nobel Nv Calibrador y su uso en un ensayo inmunologico.
US5851787A (en) * 1992-04-20 1998-12-22 The General Hospital Corporation Nucleic acid encoding amyloid precursor-like protein and uses thereof
US5708141A (en) * 1992-05-11 1998-01-13 Corvas International, Inc. Neutrophil inhibitors
DE4218257A1 (de) * 1992-06-03 1993-12-09 Behringwerke Ag Verfahren zur immunchemischen Bestimmung eines Analyten
US5688936A (en) * 1992-06-11 1997-11-18 The Regents Of The University Of California Vesicle membrane transport proteins
US5395754A (en) * 1992-07-31 1995-03-07 Hybritech Incorporated Membrane-based immunoassay method
US5447838A (en) * 1992-08-05 1995-09-05 Hybritech Incorporated Protein-dye conjugate for confirmation of correct dilution of calibrators
US5789183A (en) * 1992-08-14 1998-08-04 University Of Arkansas Serological detection and identification of rice blast
US5354692A (en) * 1992-09-08 1994-10-11 Pacific Biotech, Inc. Analyte detection device including a hydrophobic barrier for improved fluid flow
AU689091B2 (en) * 1992-12-18 1998-03-26 Cell Med, Inc. Assay and treatment for demyelinating diseases such as multiple sclerosis
DE69322847T2 (de) * 1993-01-13 1999-05-27 Idemitsu Kosan Co. Ltd., Tokio/Tokyo Monoklonaler Antikörper gegen menschliches Ceruloplasmin
US5914241A (en) * 1993-01-19 1999-06-22 Biosite Diagnostics, Inc. Assays and kits for detecting analytes in the presence of cross-reacting substances
FR2700855B1 (fr) * 1993-01-28 1995-03-03 Commissariat Energie Atomique Dosage immunométrique d'un antigène ou d'un haptène.
US7713528B1 (en) 1993-02-18 2010-05-11 Enzo Therapeutics, Inc. Method for in vivo delivery of active compounds using reagent conjugate
US5374531A (en) * 1993-03-22 1994-12-20 Zynaxis, Inc. Immunoassay for determination of cells
DE4314254A1 (de) * 1993-04-30 1994-11-03 Boehringer Mannheim Gmbh Monoklonale Antikörper gegen CK-MB
WO1994029722A1 (en) * 1993-06-08 1994-12-22 Chronomed, Inc. Two-phase optical assay method and apparatus
CA2166871A1 (en) * 1993-07-29 1995-02-09 Neill A. Giese Receptor function assays
US5837546A (en) * 1993-08-24 1998-11-17 Metrika, Inc. Electronic assay device and method
WO1995008336A1 (en) * 1993-09-22 1995-03-30 Nichols Institute Diagnostics Graves' ophthalmopathy associated antibodies, graves' ophthalmopathy orbital antigen, and methods of use thereof
JP3356556B2 (ja) * 1993-10-22 2002-12-16 第一化学薬品株式会社 変性リポプロテイン類の測定法
US7312052B1 (en) 1993-12-08 2007-12-25 Stratagene California Polymerase compositions and uses thereof
US5695928A (en) * 1993-12-10 1997-12-09 Novartis Corporation Rapid immunoassay for detection of antibodies or antigens incorporating simultaneous sample extraction and immunogenic reaction
US6045797A (en) * 1994-03-14 2000-04-04 New York University Medical Center Treatment or diagnosis of diseases or conditions associated with a BLM domain
US5877016A (en) 1994-03-18 1999-03-02 Genentech, Inc. Human trk receptors and neurotrophic factor inhibitors
US6417324B1 (en) * 2000-04-21 2002-07-09 Tripep Ab Synthetic peptides that bind to the hepatitis B virus core and e antigens
US6933366B2 (en) * 1996-12-27 2005-08-23 Tripep Ab Specificity exchangers that redirect antibodies to bacterial adhesion receptors
US6660842B1 (en) * 1994-04-28 2003-12-09 Tripep Ab Ligand/receptor specificity exchangers that redirect antibodies to receptors on a pathogen
US6040137A (en) * 1995-04-27 2000-03-21 Tripep Ab Antigen/antibody specification exchanger
US6140099A (en) * 1994-05-20 2000-10-31 The Trustees Of The University Of Pennsylvania Method of delaying fetal membrane rupture by inhibiting matrix metalloproteinase-9 activity
US5708142A (en) 1994-05-27 1998-01-13 Genentech, Inc. Tumor necrosis factor receptor-associated factors
US6107045A (en) 1994-06-30 2000-08-22 Oklahoma Medical Research Foundation Antibodies to lipoproteins and apolipoproteins and methods of use thereof
ATE201445T1 (de) 1994-08-12 2001-06-15 Myriad Genetics Inc Mutationen des mit 17q verbundenen ovarial- und brustkrebs empfindlichkeitsgens
ATE209660T1 (de) 1994-08-12 2001-12-15 Myriad Genetics Inc 17q-verbundenes ovarial- und brustkrebs empfindlichkeitsgen
US5556752A (en) 1994-10-24 1996-09-17 Affymetrix, Inc. Surface-bound, unimolecular, double-stranded DNA
US8236493B2 (en) * 1994-10-21 2012-08-07 Affymetrix, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US6974666B1 (en) * 1994-10-21 2005-12-13 Appymetric, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
JP2729159B2 (ja) * 1994-10-31 1998-03-18 日清製粉株式会社 ヒトグリセンチンのモノクローナル抗体、この抗体を産生するハイブリドーマおよびそれを用いるヒトグリセンチンの定量法
PT789575E (pt) 1994-11-02 2008-12-15 Nps Pharma Inc Canais de sódio específicos do sistema nervoso periférico, adn que os codificam, rastreio de medicamentos e métodos para a sua produção e utilização
US5837524A (en) * 1994-12-15 1998-11-17 Sugen, Inc. PYK2 related polynucleotide products
IL114615A0 (en) 1995-07-16 1995-11-27 Yeda Res & Dev Modulators of the function of fas receptors and other proteins
US5837815A (en) * 1994-12-15 1998-11-17 Sugen, Inc. PYK2 related polypeptide products
US5807989A (en) * 1994-12-23 1998-09-15 New York University Methods for treatment or diagnosis of diseases or disorders associated with an APB domain
US6300482B1 (en) 1995-01-03 2001-10-09 Max-Flanck-Gesellschaft Zuer For{Overscore (D)}Erung Der MDKI, a novel receptor tyrosine kinase
US5569608A (en) * 1995-01-30 1996-10-29 Bayer Corporation Quantitative detection of analytes on immunochromatographic strips
US5731153A (en) * 1996-08-26 1998-03-24 The Regents Of The University Of California Identification of random nucleic acid sequence aberrations using dual capture probes which hybridize to different chromosome regions
US5783387A (en) * 1995-02-06 1998-07-21 The Regents Of The University Of California Method for identifying and quantifying nucleic acid sequence aberrations
US5751629A (en) * 1995-04-25 1998-05-12 Irori Remotely programmable matrices with memories
US6329139B1 (en) 1995-04-25 2001-12-11 Discovery Partners International Automated sorting system for matrices with memory
US6416714B1 (en) * 1995-04-25 2002-07-09 Discovery Partners International, Inc. Remotely programmable matrices with memories
US5874214A (en) * 1995-04-25 1999-02-23 Irori Remotely programmable matrices with memories
US6017496A (en) * 1995-06-07 2000-01-25 Irori Matrices with memories and uses thereof
US5741462A (en) * 1995-04-25 1998-04-21 Irori Remotely programmable matrices with memories
US6331273B1 (en) 1995-04-25 2001-12-18 Discovery Partners International Remotely programmable matrices with memories
US5686257A (en) * 1995-04-26 1997-11-11 Schering Corporation Binding compositions for mammalian T cell antigens and related reagents
US6147106A (en) * 1997-08-20 2000-11-14 Sugen, Inc. Indolinone combinatorial libraries and related products and methods for the treatment of disease
AU6113396A (en) 1995-06-14 1997-01-15 Regents Of The University Of California, The Novel high affinity human antibodies to tumor antigens
US7635597B2 (en) * 1995-08-09 2009-12-22 Bayer Healthcare Llc Dry reagent particle assay and device having multiple test zones and method therefor
US5616465A (en) 1995-08-09 1997-04-01 The Regents Of The University Of California Detection and isolation of nucleic acid sequences using competitive hybridization probes
US6027879A (en) * 1995-08-09 2000-02-22 The Regents Of The University Of California Detection and isolation of nucleic acid sequences using a bifunctional hybridization probe
US5660990A (en) * 1995-08-18 1997-08-26 Immunivest Corporation Surface immobilization of magnetically collected materials
US5733728A (en) * 1995-08-18 1998-03-31 Regents Of The University Of Colorado Detecting and treating heart failure
US7455964B1 (en) 1996-07-15 2008-11-25 The Hospital For Sick Children Genes from the 20q13 amplicon and their uses
US7119174B2 (en) * 1995-12-18 2006-10-10 Sugen, Inc. Diagnosis and treatment of AUR1 and/or AUR2 related disorders
US6716575B2 (en) 1995-12-18 2004-04-06 Sugen, Inc. Diagnosis and treatment of AUR1 and/or AUR2 related disorders
US5837492A (en) 1995-12-18 1998-11-17 Myriad Genetics, Inc. Chromosome 13-linked breast cancer susceptibility gene
JP3449419B2 (ja) 1995-12-22 2003-09-22 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデーション ＫＶＬＱＴ１をコードするＱＴ延長症候群遺伝子およびそのｍｉｎＫとの関連
US7888466B2 (en) 1996-01-11 2011-02-15 Human Genome Sciences, Inc. Human G-protein chemokine receptor HSATU68
US5770086A (en) * 1996-01-25 1998-06-23 Eureka| Science Corp. Methods and apparatus using hydrogels
US5942385A (en) * 1996-03-21 1999-08-24 Sugen, Inc. Method for molecular diagnosis of tumor angiogenesis and metastasis
US6531578B1 (en) 1996-04-12 2003-03-11 Robert Webber Immunoassay method employing monoclonal antibody reactive to human iNOS
US5968839A (en) * 1996-05-13 1999-10-19 Metrika, Inc. Method and device producing a predetermined distribution of detectable change in assays
EP0979101B1 (en) 1996-07-03 2010-10-27 Merial, Inc. Recombinant canine adenovirus 2 (cav2) containing exogenous dna
US6524578B1 (en) 1996-07-10 2003-02-25 Scott E. Tackett Use of nuclease to reduce wrinkles and discolorations in humans
DE19629444A1 (de) * 1996-07-22 1998-01-29 Behringwerke Ag Sensitivitätssteigerung bei der immunchemischen Bestimmung eines Analyten
US6297027B1 (en) 1996-07-31 2001-10-02 Purina Mills, Inc. Bovine leptin protein, nucleic acid sequences coding therefor and uses thereof
US6277592B1 (en) 1996-07-31 2001-08-21 Purina Mills, Inc. Porcine leptin protein, nucleic acid sequences coding therefor and uses thereof
US5851984A (en) * 1996-08-16 1998-12-22 Genentech, Inc. Method of enhancing proliferation or differentiation of hematopoietic stem cells using Wnt polypeptides
US6159462A (en) * 1996-08-16 2000-12-12 Genentech, Inc. Uses of Wnt polypeptides
US5945345A (en) * 1996-08-27 1999-08-31 Metrika, Inc. Device for preventing assay interference using silver or lead to remove the interferant
US6001658A (en) * 1996-09-13 1999-12-14 Diagnostic Chemicals Limited Test strip apparatus and method for determining presence of analyte in a fluid sample
US5795784A (en) 1996-09-19 1998-08-18 Abbott Laboratories Method of performing a process for determining an item of interest in a sample
US5856194A (en) 1996-09-19 1999-01-05 Abbott Laboratories Method for determination of item of interest in a sample
EA199900355A1 (ru) 1996-10-01 2000-08-28 Джерон Корпорейшн Теломераза обратная тринскриптаза
US6004791A (en) 1996-11-13 1999-12-21 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Protein tyrosine phosphatase PTP20 and related products and methods
US6660481B2 (en) * 1996-12-09 2003-12-09 Osteometer Biotech A/S Sandwich assays for collagen type I fragments
EP1780277A1 (en) 1997-01-15 2007-05-02 Yeda Research And Development Company, Ltd. IFN receptor 1 binding proteins, DNA encoding them, and methods of modulating cellular response to interferons
US5879951A (en) * 1997-01-29 1999-03-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing unidirectional flow
EP0942992B1 (en) 1997-01-31 2007-03-07 Genentech, Inc. O-fucosyltransferase
US20040241645A1 (en) * 1997-01-31 2004-12-02 Genentech, Inc. O-fucosyltransferase
PT966533E (pt) 1997-02-07 2010-01-26 Univ Ramot Factor neurotrófico iii dependente da actividade (adnf iii)
US20050101032A1 (en) * 1997-02-10 2005-05-12 Metrika, Inc. Assay device, composition, and method of optimizing assay sensitivity
DE69838724T2 (de) 1997-03-21 2008-10-30 Stratagene California, La Jolla Polymerase-verbessernder faktor (pef)-enthaltende extrakte, pef proteinkomplexe, isoliertes pef protein und verfahren zur reinigung und identifizierung
US5955355A (en) * 1997-03-27 1999-09-21 Millennium Pharmaceuticals, Inc. Chromosome 18 marker
US5866412A (en) * 1997-03-27 1999-02-02 Millennium Pharmaceuticals, Inc. Chromosome 18 marker
US5939316A (en) * 1997-03-27 1999-08-17 Millennium Pharmaceuticals, Inc. Chromosome 18 marker
US5914394A (en) * 1997-03-27 1999-06-22 Millenium Pharmaceuticals, Inc. Methods and compositions for the diagnosis and treatment of neuropsychiatric disorders
DE122005000026I1 (de) 1997-04-07 2005-08-04 Genentech Inc Anti-VEGF Antik¦rper.
SI0973804T1 (sl) 1997-04-07 2007-06-30 Genentech Inc Proti-VEGF protitelesa
EP2006303A1 (en) 1997-04-09 2008-12-24 Intellect Neurosciences, Inc. Recombinant antibodies specific for Beta-Amyloid ends, DNA encoding and methods of use thereof
US6818440B2 (en) * 1997-04-28 2004-11-16 Sugen, Inc. Diagnosis and treatment of alk-7 related disorders
US6103536A (en) 1997-05-02 2000-08-15 Silver Lake Research Corporation Internally referenced competitive assays
US5939252A (en) * 1997-05-09 1999-08-17 Lennon; Donald J. Detachable-element assay device
US6228641B1 (en) 1997-05-20 2001-05-08 Sugen, Inc. Diagnosis and treatment of PTP04 related disorders
US6210976B1 (en) 1997-06-10 2001-04-03 Medlyte Diagnostics, Inc. Methods for early detection of heart disease
US7115710B2 (en) * 1997-06-11 2006-10-03 Sugen, Inc. Diagnosis and treatment of PTP related disorders
JP2002503963A (ja) 1997-06-11 2002-02-05 ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド ヒト腫瘍壊死因子受容体ｔｒ９
US6342593B1 (en) 1997-06-11 2002-01-29 Sugen, Inc. Diagnosis and treatment of ALP related disorders
US6388063B1 (en) * 1997-06-18 2002-05-14 Sugen, Inc. Diagnosis and treatment of SAD related disorders
US6235769B1 (en) 1997-07-03 2001-05-22 Sugen, Inc. Methods of preventing and treating neurological disorders with compounds that modulate the function of the C-RET receptor protein tyrosine kinase
US6391547B1 (en) * 1997-09-09 2002-05-21 Center For The Application Of Molecular Biology To International Agriculture Microbial β-glucuronidase genes, gene products and uses thereof
US7087420B1 (en) 1997-07-17 2006-08-08 Cambia Microbial β-glucuronidase genes, gene products and uses thereof
US20040067531A1 (en) * 1997-08-20 2004-04-08 Sugen, Inc. Methods of modulating protein tyrosine kinase function with substituted indolinone compounds
US6960457B1 (en) 1997-09-04 2005-11-01 Stanford University Reversible immobilization of arginine-tagged moieties on a silicate surface
US20140080177A1 (en) * 1997-09-26 2014-03-20 Pieris Ag Anticalins
JP2001518453A (ja) * 1997-09-29 2001-10-16 ユニバーシティ オブ メリーランド， ボルチモア 悪性腫瘍の生体マーカーとしての改変されたｄｎａシンセソーム成分
EP2386630A1 (en) 1997-10-14 2011-11-16 Darwin Molecular Corporation Thymidine kinase mutants and fusion proteins having thymidine kinase and guanylate kinase activities
DE69839942D1 (de) 1997-10-29 2008-10-09 Genentech Inc Verwendung des wnt-1 induzierten sekretierten polypeptids wisp-1
ES2316173T3 (es) 1997-10-29 2009-04-01 Genentech, Inc. Genes inducibles por wnt-1.
CN1174993C (zh) 1997-11-03 2004-11-10 人体基因组科学有限公司 Vegi,一种血管发生和肿瘤生长的抑制剂
US6224882B1 (en) 1997-11-07 2001-05-01 Protein Science Corp. Insect cells or fractions as adjuvant for antigens
US6437563B1 (en) 1997-11-21 2002-08-20 Quantum Design, Inc. Method and apparatus for making measurements of accumulations of magnetically susceptible particles combined with analytes
US7192589B2 (en) 1998-09-16 2007-03-20 Genentech, Inc. Treatment of inflammatory disorders with STIgMA immunoadhesins
ATE410512T1 (de) 1997-11-21 2008-10-15 Genentech Inc Plättchen-spezifische antigene und deren pharmazeutische verwendung
US6221585B1 (en) 1998-01-15 2001-04-24 Valigen, Inc. Method for identifying genes underlying defined phenotypes
US6531502B1 (en) * 1998-01-21 2003-03-11 Sugen, Inc. 3-Methylidenyl-2-indolinone modulators of protein kinase
CA2318403A1 (en) * 1998-01-21 1999-07-29 Sugen, Inc. Human orthologues of wart
US6764830B1 (en) 1998-01-23 2004-07-20 The Regents Of The University Of California Thermomyces lanuginosus kinesin motor protein and methods of screening for modulators of kinesin proteins
AU754436B2 (en) 1998-03-16 2002-11-14 Millennium Pharmaceuticals, Inc. Methods and compositions for diagnosing and treating chromosome-18p related disorders
US20040176572A1 (en) * 1998-03-16 2004-09-09 Freimer Nelson B. Methods of compositions for diagnosing and treating chromosome-18p related disorders
DE69939374D1 (de) 1998-03-17 2008-10-02 Genentech Inc Zu vegf und bmp1 homologe polypeptide
US6274314B1 (en) * 1998-04-02 2001-08-14 Nyxis Neurotherapies, Inc. Diagnostic assay for the modified nucleosides pseudouridine, 7-methyladenosine, or 1-methyladenosine
US6514981B1 (en) * 1998-04-02 2003-02-04 Sugen, Inc. Methods of modulating tyrosine protein kinase function with indolinone compounds
AU3642499A (en) 1998-04-14 1999-11-01 Sugen, Inc. Ste20-related protein kinases
US7157083B2 (en) * 1998-04-17 2007-01-02 Surrogate Pharmaceutical Pathways, Llc Compositions and methods for treating retroviral infections
US20060019404A1 (en) * 1998-05-06 2006-01-26 Blatt Joel M Quantitative assay with extended dynamic range
CN102274272A (zh) 1998-05-19 2011-12-14 研究发展基金会 三萜组合物和它们的使用方法
AU762799B2 (en) 1998-06-12 2003-07-03 Henry M. Jackson Foundation For The Advancement Of Military Medicine Enhancement of B cell activation and immunoglobulin secretion by co-stimulation of receptors for antigen and EBV Gp350/220
US7402400B2 (en) 2001-07-03 2008-07-22 Regents Of The University Of California Mammalian sweet taste receptors
EP1806362B1 (en) 1998-07-28 2010-07-21 The Regents of the University of California Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction
ATE332373T1 (de) * 1998-08-21 2006-07-15 Immunex Corp Menschlisches il-1 epsilon dna und polypeptide
US6627747B1 (en) 1998-09-09 2003-09-30 Millenium Pharmaceuticals, Inc. Essential bacterial genes and their use
US20070178475A1 (en) * 1998-09-17 2007-08-02 Nehls Michael C Novel human polynucleotides and polypeptides encoded thereby
US6680335B2 (en) 1998-09-28 2004-01-20 Sugen, Inc. Methods of modulating protein tyrosine kinase function with substituted indolinone compounds
US6368793B1 (en) * 1998-10-14 2002-04-09 Microgenomics, Inc. Metabolic selection methods
US7091324B2 (en) 1998-11-05 2006-08-15 Board Of Trustees Of Leland Stanford Junior University Prevention and treatment of HCV infection employing antibodies directed against conformational epitopes
SI1135498T1 (sl) 1998-11-18 2008-06-30 Genentech Inc Variante protitelesa z višjo vezavno afiniteto vprimerjavi z izvirnimi protitelesi
US20040009535A1 (en) 1998-11-27 2004-01-15 Celltech R&D, Inc. Compositions and methods for increasing bone mineralization
BRPI9915679B8 (pt) * 1998-11-27 2021-05-25 Darwin Discovery Ltd composições e métodos para aumentar a mineralização óssea
US7273618B2 (en) * 1998-12-09 2007-09-25 Chiron Corporation Method for administering agents to the central nervous system
ATE300957T1 (de) 1998-12-22 2005-08-15 Genentech Inc Antagonisten von vaskular-endothelialen zellwachstumsfaktoren und ihre anwendung
US6861442B1 (en) 1998-12-30 2005-03-01 Sugen, Inc. PYK2 and inflammation
US20020164784A1 (en) * 2000-10-27 2002-11-07 Walke D. Wade Novel human 7TM proteins and polynucleotides encoding the same
US20020031802A1 (en) * 2000-05-12 2002-03-14 Yi Hu Novel seven transmembrane proteins and polynucleotides encoding the same
US6570003B1 (en) * 2001-01-09 2003-05-27 Lexion Genetics Incorporated Human 7TM proteins and polynucleotides encoding the same
US20020103359A1 (en) * 1999-12-07 2002-08-01 Gregory Donoho Novel human membrane proteins and polynucleotides encoding the same
US20020038013A1 (en) * 2000-02-04 2002-03-28 Gregory Donoho Novel human membrane proteins and polynucleotides encoding the same
US6579715B1 (en) 1999-01-19 2003-06-17 Lexicon Genetics Incorporated Mammalian cortexin-like proteins and polynucleotides encoding the same
US7625859B1 (en) 2000-02-16 2009-12-01 Oregon Health & Science University HER-2 binding antagonists
US7396810B1 (en) * 2000-08-14 2008-07-08 Oregon Health Sciences University Compositions and methods for treating cancer by modulating HER-2 and EGF receptors
US7393823B1 (en) 1999-01-20 2008-07-01 Oregon Health And Science University HER-2 binding antagonists
US6303749B1 (en) 1999-01-29 2001-10-16 Amgen Inc. Agouti and agouti-related peptide analogs
EP1153037A1 (en) 1999-02-09 2001-11-14 Lexicon Genetics Incorporated Human uncoupling proteins and polynucleotides encoding the same
GB9903841D0 (en) * 1999-02-20 1999-04-14 Imp College Innovations Ltd Diagnosis and treatment of cancer
US6864235B1 (en) * 1999-04-01 2005-03-08 Eva A. Turley Compositions and methods for treating cellular response to injury and other proliferating cell disorders regulated by hyaladherin and hyaluronans
US6911429B2 (en) * 1999-04-01 2005-06-28 Transition Therapeutics Inc. Compositions and methods for treating cellular response to injury and other proliferating cell disorders regulated by hyaladherin and hyaluronans
DE60035267T2 (de) 1999-04-12 2008-02-21 Dainippon Sumitomo Pharma Co., Ltd. Verfahren zur analyse der menge an intraabdominalem fettgewebe
US20080145347A1 (en) * 1999-04-29 2008-06-19 Steiner Mitchell S p-Hyde sequences in the Rat
US20020110809A1 (en) * 1999-04-30 2002-08-15 Nehls Michael C. Novel human polynucleotides and polypeptides encoded thereby
US7566452B1 (en) 1999-05-04 2009-07-28 New York University Cancer treatment with endothelin receptor antagonists
US20020095031A1 (en) * 1999-05-04 2002-07-18 Nehls Michael C. Novel human polynucleotides and polypeptides encoded thereby
US20030186311A1 (en) * 1999-05-21 2003-10-02 Bioforce Nanosciences, Inc. Parallel analysis of molecular interactions
IL130225A0 (en) 1999-05-31 2000-06-01 Yissum Res Dev Co Novel uses of antibodies against ache and peptides thereof
AU784533B2 (en) * 1999-08-24 2006-04-27 Lexicon Genetics Incorporated Sequence derived from a human mammary gland CDNA library
KR20050004240A (ko) * 1999-08-31 2005-01-12 제넨테크, 인크. 종양 치료용 조성물 및 방법
AU7101700A (en) 1999-09-02 2001-03-26 Lexicon Genetics Incorporated Human calcium dependent proteases and polynucleotides encoding the same
US6716614B1 (en) 1999-09-02 2004-04-06 Lexicon Genetics Incorporated Human calcium dependent proteases, polynucleotides encoding the same, and uses thereof
US20080003673A1 (en) * 1999-09-02 2008-01-03 Alejandro Abuin Novel human proteases and polynucleotides encoding the same
US6509456B2 (en) * 2000-02-11 2003-01-21 Lexicon Genetics Incorporated Human proteases and polynucleotides encoding the same
US6448388B1 (en) 2000-08-16 2002-09-10 Lexicon Genetics Incorporated Human proteases and polynucleotides encoding the same
US20050153323A1 (en) * 2000-07-28 2005-07-14 Yi Hu Novel human proteases and polynucleotides encoding the same
US20030050464A1 (en) * 2000-07-28 2003-03-13 Yi Hu Novel human proteases and polynucleotides encoding the same
US7459540B1 (en) 1999-09-07 2008-12-02 Amgen Inc. Fibroblast growth factor-like polypeptides
US7408047B1 (en) 1999-09-07 2008-08-05 Amgen Inc. Fibroblast growth factor-like polypeptides
WO2001018206A1 (en) * 1999-09-08 2001-03-15 Lexicon Genetics Incorporated Human g-protein coupled 7 transmembrane receptor and polynucleotides encoding the same
US6500629B1 (en) 1999-09-13 2002-12-31 Equitech Laboratories, Inc. Materials and methods for detection and quantitation of an analyte
US6900043B1 (en) * 1999-09-21 2005-05-31 Amgen Inc. Phosphatases which activate map kinase pathways
US6790660B1 (en) * 2001-09-18 2004-09-14 Lexicon Genetics Incorporated Human kielin-like proteins and polynucleotides encoding the same
EP1633872A2 (en) * 1999-09-24 2006-03-15 Lexicon Genetics Incorporated Novel human protease inhibitor-like proteins and polynucleotides encoding the same
AU780770B2 (en) 1999-09-24 2005-04-14 Lexicon Pharmaceuticals, Inc. Novel human endothelin converting enzyme-like proteins and polynucleotides encoding the same
US6867291B1 (en) * 2000-09-15 2005-03-15 Lexicon Genetics Incorporated Human hemicentin proteins and polynucleotides encoding the same
US6586230B1 (en) * 2000-10-27 2003-07-01 Lexicon Genetics Incorporated Human kinase and polynucleotides encoding the same
US20080050809A1 (en) * 1999-09-28 2008-02-28 Alejandro Abuin Novel human kinases and polynucleotides encoding the same
US6511840B1 (en) 2000-06-15 2003-01-28 Lexicon Genetics Incorporated Human kinase proteins and polynucleotides encoding the same
US6746861B2 (en) 2000-01-18 2004-06-08 Lexicon Genetics Incorporated Human kinase protein and polynucleotides encoding the same
US6734009B2 (en) 2000-12-27 2004-05-11 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US6734010B2 (en) * 2001-05-09 2004-05-11 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US6476210B2 (en) 2000-10-12 2002-11-05 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US6593125B2 (en) 2000-11-20 2003-07-15 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US6720173B1 (en) 1999-11-08 2004-04-13 Lexicon Genetics Incorporated Human kinase protein and polynucleotides encoding the same
US6841377B1 (en) 2001-06-13 2005-01-11 Lexicon Genetics Incorporated Human kinase and polynucleotides encoding the same
US6797510B1 (en) * 2001-05-24 2004-09-28 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US6541252B1 (en) 2000-05-19 2003-04-01 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US6759527B2 (en) 2001-03-20 2004-07-06 Lexicon Genetics Incorporated Human kinase and polynucleotides encoding the same
US6716616B1 (en) * 1999-09-28 2004-04-06 Lexicon Genetics Incorporated Human kinase proteins and polynucleotides encoding the same
JP2003512027A (ja) * 1999-09-29 2003-04-02 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトカルボキシペプチダーゼおよびそれをコードするポリヌクレオチド
US6794132B2 (en) 1999-10-02 2004-09-21 Biosite, Inc. Human antibodies
US7135287B1 (en) 1999-10-02 2006-11-14 Biosite, Inc. Human antibodies
US20070111259A1 (en) * 1999-10-02 2007-05-17 Medarex, Inc. Human antibodies
WO2001027274A1 (en) 1999-10-12 2001-04-19 Lexicon Genetics Incorporated Human ldl receptor family proteins and polynucleotides encoding the same
AU1198701A (en) * 1999-10-13 2001-04-23 Lexicon Genetics Incorporated Novel human membrane proteins
EP1226170B1 (en) * 1999-10-18 2008-07-30 Lexicon Pharmaceuticals, Inc. Human chordin and polynucleotides encoding the same
US20030013865A1 (en) * 2001-03-12 2003-01-16 Yu Xuanchuan (Sean) Novel human EGF-family proteins and polynucleotides encoding the same
US6743907B1 (en) 1999-10-19 2004-06-01 Lexicon Genetics Incorporated Human proteins and polynucleotides encoding the same
US20080213878A1 (en) * 1999-10-19 2008-09-04 Gregory Donoho Novel human membrane proteins and polynucleotides encoding the same
CA2390182A1 (en) 1999-11-02 2001-05-10 Lexicon Genetics Incorporated Novel human transporter proteins and polynucleotides encoding the same
AU783485B2 (en) * 1999-11-10 2005-11-03 Lexicon Pharmaceuticals, Inc. Human atpase proteins and polynucleotides encoding the same
EP1242588A2 (en) 1999-11-12 2002-09-25 Lexicon Genetics Incorporated Human proteins with homology to carboxypeptidases and polynucleotides encoding the same
DE60025526T2 (de) 1999-11-16 2006-08-24 Genentech, Inc., South San Francisco Elisa für vegf
US6943010B1 (en) * 1999-11-19 2005-09-13 Hortense W. Dodo Down-regulation and silencing of allergen genes in transgenic peanut seeds
ES2629683T3 (es) 1999-11-30 2017-08-14 Mayo Foundation For Medical Education And Research B7-H1, una nueva molécula inmunorreguladora
US6680209B1 (en) * 1999-12-06 2004-01-20 Biosite, Incorporated Human antibodies as diagnostic reagents
AU785082B2 (en) 1999-12-07 2006-09-14 Lexicon Pharmaceuticals, Inc. Novel human kinase proteins and polynucleotides encoding the same
JP2004500060A (ja) 1999-12-09 2004-01-08 レキシコン・ジェネティクス・インコーポレーテッド ヒトａｄａｍ−ｔｓプロテアーゼおよびそれをコードするポリヌクレオチド
WO2001042477A1 (en) * 1999-12-13 2001-06-14 Lexicon Genetics Incorporated Novel human transferase proteins and polynucleotides encoding the same
AU784266B2 (en) 1999-12-22 2006-03-02 Sugen, Inc. Indolinone derivatives for modulation of c-kit tyrosine kinase
JP2003529341A (ja) * 1999-12-22 2003-10-07 レキシコン・ジェネティクス・インコーポレーテッド ヒト膜タンパクおよびそれをコードするポリヌクレオチド
AU2092901A (en) * 1999-12-22 2001-07-03 Lexicon Genetics Incorporated Polynucleotides encoding human protease homologs
EP2163625B1 (en) 1999-12-23 2014-05-21 Genentech, Inc. IL-17 and IL-17R homologous polypeptides and therapeutic uses thereof
JP2004502402A (ja) * 2000-01-06 2004-01-29 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトプロテアーゼおよびそれをコードするポリヌクレオチド
CA2398483A1 (en) * 2000-01-26 2001-08-16 Lexicon Genetics Incorporated Human neurexin-like proteins and polynucleotides encoding the same
US20030054513A1 (en) * 2000-01-28 2003-03-20 Gregory Donoho Novel human enzymes and polynucleotides encoding the same
JP2003520607A (ja) * 2000-01-28 2003-07-08 レキシコン・ジェネティクス・インコーポレーテッド ヒト膜タンパクおよびそれをコードするポリヌクレオチド
CA2399663A1 (en) * 2000-02-04 2001-08-09 Lexicon Genetics Incorporated Novel human enzymes and polynucleotides encoding the same
DK1255752T3 (da) 2000-02-15 2007-11-26 Sugen Inc Pyrrolsubstituerede 2-indolinonproteinkinaseinhibitorer
AU2001238503A1 (en) * 2000-02-17 2001-08-27 Lexicon Genetics Incorporated Novel human thrombospondin repeat proteins and polynucleotides encoding the same
EP1259610A2 (en) 2000-02-29 2002-11-27 Lexicon Genetics Incorporated Human transporter proteins and polynucleotides encoding the same
WO2001064903A2 (en) * 2000-02-29 2001-09-07 Lexicon Genetics Incorporated Novel human transferase proteins and polynucleotides encoding the same
US20040002068A1 (en) 2000-03-01 2004-01-01 Corixa Corporation Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
WO2001066744A2 (en) * 2000-03-06 2001-09-13 Lexicon Genetics Incorporated Human transporter proteins and polynucleotides encoding the same
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
CA2402227A1 (en) 2000-03-10 2001-09-20 Lexicon Genetics Incorporated Human g-coupled protein receptor kinases and polynucleotides encoding the same
WO2001068871A2 (en) * 2000-03-13 2001-09-20 Lexicon Genetics Incorporated Human phospholipases and polynucleotides encoding the same
AU2001250898A1 (en) * 2000-03-17 2001-10-03 The Salk Institute For Biological Studies Compositions associated with complex formation
JP2004501609A (ja) * 2000-03-20 2004-01-22 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒト分泌タンパク質及び該タンパク質をコードするポリヌクレオチド
AU2001218871A1 (en) * 2000-03-21 2001-10-03 Takao Arai Monoclonal antibody and method and kit for the immunoassay of soluble human st2 with the use of the same
US7514239B2 (en) 2000-03-28 2009-04-07 Amgen Inc. Nucleic acid molecules encoding beta-like glycoprotein hormone polypeptides and heterodimers thereof
JP5079962B2 (ja) 2000-03-31 2012-11-21 ノヴァークス ＴＧＦβ阻害剤を発現する遺伝的に改変された細胞であって、肺癌細胞である細胞
AU2001251283A1 (en) * 2000-04-03 2001-10-15 Lexicon Genetics Incorporated Human ion channel protein and polynucleotides encoding the same
AU2001257043A1 (en) * 2000-04-12 2001-10-30 Lexicon Genetics Incorporated Human metalloprotease and polynucleotides encoding the same
US7364867B2 (en) * 2000-04-17 2008-04-29 The Mount Sinai School Of Medicine Method of identifying bitter compounds by employing TRP8, a transient receptor potential channel expressed in taste receptor cells
EP1276873A2 (en) 2000-04-25 2003-01-22 Lexicon Genetics Incorporated Human kinase proteins and polynucleotides encoding the same
WO2001081411A2 (en) * 2000-04-27 2001-11-01 Lexicon Genetics Incorporated Human 7-transmembrane g-protein coupled receptors and polynucleotides encoding the same
US7030219B2 (en) * 2000-04-28 2006-04-18 Johns Hopkins University B7-DC, Dendritic cell co-stimulatory molecules
DK2026073T3 (en) 2000-04-29 2016-07-25 Univ Iowa Res Found Diagnosis and treatment of macular degeneration-related disorders
AU2001263107A1 (en) * 2000-05-12 2001-11-26 Lexicon Genetics Incorporated Novel human lipocalin homologs and polynucleotides encoding the same
AU2001264769A1 (en) * 2000-05-17 2001-11-26 Oregon Health And Sciences University Induction of apoptosis and cell growth inhibition by protein 4.33
AU2001263105A1 (en) * 2000-05-18 2001-11-26 Lexicon Genetics Incorporated Human semaphorin homologs and polynucleotides encoding the same
AU2001274923A1 (en) * 2000-05-23 2001-12-03 Lexicon Genetics Incorporated Novel human thrombospondin-like proteins and polynucleotides encoding the same
US6790667B1 (en) 2000-05-30 2004-09-14 Lexicon Genetics Incorporated Human mitochondrial proteins and polynucleotides encoding the same
AU2001275337A1 (en) * 2000-06-07 2001-12-17 Lexicon Genetics Incorporated Novel human transporter proteins and polynucleotides encoding the same
US6465632B1 (en) * 2000-06-09 2002-10-15 Lexicon Genetics Incorporated Human phosphatases and polynucleotides encoding the same
WO2001094417A2 (en) * 2000-06-09 2001-12-13 Lexicon Genetics Incorporated Novel human seven transmembrane proteins and polynucleotides encoding the same
US20040168209A1 (en) * 2000-06-12 2004-08-26 Alejandro Abuin Novel murine polynucleotide sequences and mutant cells and mutant animals defined thereby
WO2001096528A2 (en) 2000-06-15 2001-12-20 Human Genome Sciences, Inc. Human tumor necrosis factor delta and epsilon
JP2004504064A (ja) 2000-06-22 2004-02-12 アムジエン・インコーポレーテツド Ｉｌ−１７分子およびその用途
CA2648051A1 (en) 2000-06-23 2002-01-03 Genentech, Inc. Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
DK2042597T3 (da) 2000-06-23 2014-08-11 Genentech Inc Sammensætninger og fremgangsmåder til diagnose og behandling af sygdomme, der involverer angiogenese
US6528321B1 (en) 2000-06-26 2003-03-04 Beckman Coulter, Inc. Opposable-element chromatographic assay device for detection of analytes in whole blood samples
US20030032791A1 (en) * 2000-06-26 2003-02-13 Alan Robertson Scott Novel melanocortin-4 receptor sequences and screening assays to identify compounds useful in regulating animal appetite and metabolic rate
WO2002000720A2 (en) * 2000-06-27 2002-01-03 Lexicon Genetics Incorporated Novel human gaba receptors and polynucleotides encoding the same
US20060024304A1 (en) * 2000-06-28 2006-02-02 Gerngross Tillman U Immunoglobulins comprising predominantly a Man5GlcNAc2 glycoform
PT2077279E (pt) 2000-06-28 2012-09-14 Amgen Inc Moléculas do receptor de linfopoietina estromal tímica e suas utilizações
US20060034828A1 (en) * 2000-06-28 2006-02-16 Gerngross Tillman U Immunoglobulins comprising predominantly a GlcNAcMAN5GLCNAC2 glycoform
US20060029604A1 (en) * 2000-06-28 2006-02-09 Gerngross Tillman U Immunoglobulins comprising predominantly a GlcNAc2Man3GlcNAc2 glycoform
US20060257399A1 (en) * 2000-06-28 2006-11-16 Glycofi, Inc. Immunoglobulins comprising predominantly a Man5GIcNAc2 glycoform
US20060034830A1 (en) * 2000-06-28 2006-02-16 Gerngross Tillman U Immunoglobulins comprising predominantly a GalGlcNAcMan5GLcNAc2 glycoform
AU2002224553A1 (en) * 2000-07-21 2002-02-05 Incyte Genomics, Inc. Human proteases
US6632681B1 (en) 2000-07-24 2003-10-14 Ey Laboratories Reagent delivery device and method of use
US6887685B1 (en) 2000-07-25 2005-05-03 Lexicon Genetics Incorporated Human thymosin protein and polynucleotides encoding the same
US20020076780A1 (en) * 2000-08-16 2002-06-20 Turner C. Alexander Novel human ion channel proteins and polynucleotides encoding the same
RU2286172C2 (ru) * 2000-08-17 2006-10-27 Трипеп Аб Вакцины, содержащие рибавирин, и способы их использования
CA2419418A1 (en) 2000-08-17 2002-02-21 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US7022830B2 (en) * 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
US6680059B2 (en) * 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
JP2004531201A (ja) * 2000-08-22 2004-10-14 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトプロテアーゼ及び該プロテアーゼをコードするポリヌクレオチド
WO2002016435A2 (en) * 2000-08-22 2002-02-28 Lexicon Genetics Incorporated Human 7tm proteins and polynucleotides encoding the same
JP4932125B2 (ja) 2000-08-25 2012-05-16 ビーエーエスエフ プラント サイエンス ゲーエムベーハー 新規プレニルプロテアーゼをコードする植物ポリヌクレオチド
EP1197550A3 (en) * 2000-08-25 2002-11-20 Pfizer Products Inc. Methods and compositions for diagnosing and treating disorders involving angiogenesis
JP2003000268A (ja) 2000-08-25 2003-01-07 Pfizer Prod Inc 血管新生にかかわる疾患を診断および治療するための方法および組成物
WO2002018555A2 (en) * 2000-08-31 2002-03-07 Lexicon Genetics Incorporated Human kinase proteins and polynucleotides encoding the same
US7491801B2 (en) * 2000-09-01 2009-02-17 International Bioimmune Systems, Inc. Identification and development of specific monoclonal antibodies to squamous cell carcinoma
AU2001285327A1 (en) * 2000-09-01 2002-03-22 Lexicon Genetics Incorporated Human gaba transporter protein and polynucleotides encoding the same
US20030176344A1 (en) * 2000-09-14 2003-09-18 Decode Genetics Ehf. Human osteoporosis gene
WO2002026107A2 (en) * 2000-09-25 2002-04-04 The Regents Of The University Of California Model for neurodegenerative diseases involving amyloid accumulation
WO2002026981A2 (en) * 2000-09-27 2002-04-04 Lexicon Genetics Incorporated Human protease inhibitor proteins and polynucleotides encoding the same
US6787352B2 (en) 2000-09-27 2004-09-07 Lexicon Genetics Incorporated Polynucleotides encoding human ion-exchanger proteins
US6777232B1 (en) 2000-10-02 2004-08-17 Lexicon Genetics Incorporated Human membrane proteins and polynucleotides encoding the same
WO2002033089A2 (en) * 2000-10-05 2002-04-25 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Ixodes scapularis tissue factor pathway inhibitor
US7001763B1 (en) 2000-10-17 2006-02-21 Lexicon Genetics Incorporated Human semaphorin proteins and polynucleotides encoding the same
DE60116889T2 (de) * 2000-10-17 2006-09-14 Besst-Test Aps Test zum direkten nachweis eines inflammatorischen anzeigers ein einer körperflüssigkeitsprobe
US7232880B2 (en) * 2000-10-27 2007-06-19 Oregon Health & Science University Mutant IGFBP-3 molecules that do not bind to IGFS, but retain their ability to functionally bind IGFBP-3 receptor
WO2002036633A2 (en) * 2000-10-30 2002-05-10 Lexicon Genetics Incorporated Human 7tm proteins and polynucleotides encoding the same
WO2002036759A2 (en) * 2000-11-01 2002-05-10 Lexicon Genetics Incorporated Polynucleotides encoding human meltrin beta (adam19) metalloendopeptidases
CA2429519A1 (en) * 2000-11-15 2002-06-27 Lexicon Genetics Incorporated Novel human secreted proteins and polynucleotides encoding the same
US20060148732A1 (en) * 2000-11-17 2006-07-06 Gutterman Jordan U Inhibition of NF-kappaB by triterpene compositions
US6989247B2 (en) 2000-11-28 2006-01-24 Celltech R & D, Inc. Compositions and methods for diagnosing or treating psoriasis
US7393921B2 (en) * 2000-12-04 2008-07-01 Institute For Systems Biology Prostate-specific polypeptide pamp and encoding nucleic acid molecules
US7408041B2 (en) 2000-12-08 2008-08-05 Alexion Pharmaceuticals, Inc. Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
US20060057651A1 (en) 2000-12-08 2006-03-16 Bowdish Katherine S Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
US9249229B2 (en) * 2000-12-08 2016-02-02 Alexion Pharmaceuticals, Inc. Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
US20040198661A1 (en) * 2000-12-08 2004-10-07 Bowdish Katherine S. Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
EP1341902A2 (en) * 2000-12-08 2003-09-10 Alexion Pharmaceuticals, Inc. Chronic lymphocytic leukemia cell line and its use for producing an antibody
EP1341906A2 (en) * 2000-12-11 2003-09-10 Lexicon Genetics Incorporated Novel human kinase and polynucleotides encoding the same
JP2004530417A (ja) * 2000-12-12 2004-10-07 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトキナーゼおよびそれをコードするポリヌクレオチド
US6583269B1 (en) * 2000-12-18 2003-06-24 Lexicon Genetics Incorporated Human protease inhibitor and polynucleotides encoding the same
WO2002050271A2 (en) * 2000-12-20 2002-06-27 Lexicon Genetics Incorporated Human ion channel protein and polynucleotides encoding the same
US6852844B1 (en) * 2000-12-20 2005-02-08 Lexicon Genetics Incorporated Human protocadherin proteins and polynucleotides encoding the same
IL140537A0 (en) * 2000-12-25 2002-02-10 Hadasit Med Res Service Educated nk t cells and their uses in the treatment of immune-related disorders
US7445802B2 (en) * 2000-12-26 2008-11-04 Yeda Research And Development Co. Ltd Site-specific in situ generation of allicin using a targeted alliinase delivery system for the treatment of cancers, tumors, infectious diseases and other allicin-sensitive diseases
WO2002068626A2 (en) * 2000-12-28 2002-09-06 Lexicon Genetics Incorporated Novel human ion channel-related proteins and polynucleotides encoding the same
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
WO2002053753A2 (en) * 2001-01-05 2002-07-11 Lexicon Genetics Incorporated Novel human lipase and polynucleotides encoding the same
WO2002053754A2 (en) * 2001-01-08 2002-07-11 Lexicon Genetics Incorporated Human protease and polynucleotides encoding the same
JP2004524835A (ja) * 2001-01-23 2004-08-19 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトキナーゼおよびそれをコードするポリヌクレオチド
JP2005502311A (ja) * 2001-01-24 2005-01-27 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトリパーゼ及び該リパーゼをコードするポリヌクレオチド
US20020127674A1 (en) * 2001-02-02 2002-09-12 Xuanchuan Yu Novel human transporter protein and polynucleotides encoding the same
WO2002064755A2 (en) 2001-02-14 2002-08-22 Anthrogenesis Corporation Post-partum mammalian placenta, its use and placental stem cells therefrom
AR042586A1 (es) 2001-02-15 2005-06-29 Sugen Inc 3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa
CA2473197A1 (en) * 2001-02-20 2002-08-29 Lexicon Genetics Incorporated Novel human protease and polynucleotides encoding the same
US20020117169A1 (en) 2001-02-27 2002-08-29 Kurz Daniel R. Cover and applicator for a portion of a mammalian body
JP3929250B2 (ja) * 2001-03-08 2007-06-13 株式会社ルネサステクノロジ 半導体装置
WO2002072774A2 (en) * 2001-03-12 2002-09-19 Lexicon Genetics Incorporated Novel human transporter proteins and polynucleotides encoding the same
US7252990B2 (en) * 2001-03-12 2007-08-07 Lexicon Genetics Incorporated Human dectin proteins and polynucleotides encoding the same
DK1411962T3 (da) 2001-03-15 2011-04-04 Neogenix Oncology Inc Terapi for pancreacancer med monoklonalt stof
US6994995B1 (en) 2001-03-16 2006-02-07 Lexicon Genetics Incorporated Human synaptotagmin and polynucleotides encoding the same
US20030228639A1 (en) * 2001-03-19 2003-12-11 Wright George L Prostate cancer markers
US6613534B2 (en) 2001-03-20 2003-09-02 Wake Forest University Health Sciences MAP-2 as a determinant of metastatic potential
US7071303B2 (en) 2001-03-28 2006-07-04 Institute For Systems Biology Androgen regulated prostate specific nucleic acids
EP1383879A4 (en) 2001-04-06 2005-05-11 Lexicon Genetics Inc HUMAN KINASES AND POLYNUCLEOTIDES ENCODING SAME
JP2004528841A (ja) 2001-04-06 2004-09-24 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトキナーゼおよびそれをコードするポリヌクレオチド
CA2443968A1 (en) 2001-04-12 2002-10-24 Imperial College Innovations Limited Diagnosis and treatment of cancer: i
CA2443493A1 (en) * 2001-04-13 2002-10-24 Wyeth Surface proteins of streptococcus pyogenes
US20070128229A1 (en) * 2002-04-12 2007-06-07 Wyeth Surface proteins of Streptococcus pyogenes
WO2002083706A1 (en) * 2001-04-16 2002-10-24 Lexicon Genetics Incorporated Nucleic acid encoding a human adenylosuccinate synthetase
US7803982B2 (en) 2001-04-20 2010-09-28 The Mount Sinai School Of Medicine Of New York University T1R3 transgenic animals, cells and related methods
MXPA03009580A (es) * 2001-04-20 2004-12-06 Sinai School Medicine Tir3, un receptor de sabor novedoso.
US20030166893A1 (en) * 2001-04-30 2003-09-04 Yi Hu Novel human nuclear transporters and polynucleotides encoding the same
US20030211464A1 (en) * 2001-05-02 2003-11-13 Charles Pidgeon Method and compositions for drug discovery
CA2446112C (en) 2001-05-08 2011-04-26 Darwin Molecular Corporation A method for regulating immune function in primates using the foxp3 protein
US20020193585A1 (en) * 2001-05-25 2002-12-19 Walke D. Wade Novel human transporter proteins and polynucleotides encoding the same
DE60225064T2 (de) 2001-05-29 2009-01-29 Lexicon Pharmaceuticals, Inc., The Woodlands Neue menschliche hydroxylasen und diese codierende polynukleotide
EP2277542B1 (en) 2001-06-01 2014-04-16 Cornell Research Foundation Inc. Modified antibodies to prostrate-specific membrane antigen and uses thereof
US20070160576A1 (en) 2001-06-05 2007-07-12 Genentech, Inc. IL-17A/F heterologous polypeptides and therapeutic uses thereof
US7235358B2 (en) * 2001-06-08 2007-06-26 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
US7026121B1 (en) * 2001-06-08 2006-04-11 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
US6905827B2 (en) * 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
EP1406645A4 (en) * 2001-06-14 2005-02-16 Lexicon Genetics Inc NEW HUMANTRANSPORTER PROTEINS AND THESE CODING POLYNUCLEOTIDE
DE60233509D1 (de) * 2001-06-20 2009-10-08 Fibron Ltd Fgfr3 blockierende antikörper, verfahren zum screening darauf und verwendungen davon
US20030018009A1 (en) * 2001-06-20 2003-01-23 Collins Douglas A. Adenosyl-cobalamin fortified compositions
AU2002305478A1 (en) * 2001-06-20 2003-01-08 Molecular Staging, Inc. Conjugates of reduced antibodies and biomolecules
EP2327985B2 (en) 2001-06-26 2019-08-21 Senomyx, Inc. T1R Hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
AU2002318186A1 (en) * 2001-07-03 2003-01-21 Lexicon Genetics Incorporated Novel human kielin-like proteins and polynucleotides encoding the same
JP4265149B2 (ja) * 2001-07-25 2009-05-20 セイコーエプソン株式会社 電気光学装置、電気光学装置の製造方法
US7270959B2 (en) 2001-07-25 2007-09-18 Oakville Hong Kong Company Limited Specimen collection container
US7300633B2 (en) * 2001-07-25 2007-11-27 Oakville Hong Kong Company Limited Specimen collection container
AUPR673001A0 (en) 2001-07-31 2001-08-23 Prince Henry's Institute Of Medical Research Pregnancy-related enzyme activity
US7744888B2 (en) 2001-08-03 2010-06-29 Abgenomics Cooperatief U.A. Methods of modulating T cell or natural killer cell activity with anti-P-selectin glycoprotein ligand 1 antibodies
WO2003062785A2 (en) 2001-08-09 2003-07-31 Syracuse Bioanalytical, Inc. Detection of bovine viral diarrhea virus in hair samples
WO2003016481A2 (en) * 2001-08-14 2003-02-27 Lexicon Genetics Incorporated Novel human collagen proteins and polynucleotides encoding the same
JP2005507654A (ja) * 2001-08-27 2005-03-24 トゥラリック インコーポレイテッド 増幅した癌遺伝子およびそれらの癌への関与
WO2003018631A2 (en) * 2001-08-27 2003-03-06 Novartis Ag Nogo receptor homologues and their use
AU2002324792A1 (en) * 2001-08-27 2003-03-10 Tularik Inc. Amplified gene involved in cancer
JP2003076656A (ja) * 2001-09-05 2003-03-14 Sony Corp 情報処理システム、情報処理装置および方法、記録媒体、並びにプログラム
EP1434993B1 (en) 2001-09-18 2013-04-24 Fibrogen, Inc. Methods of assaying connective tissue growth factor
DE60233744D1 (de) 2001-09-20 2009-10-29 Univ Texas Bestimmung der zirkulierenden therapeutischen antikörper, antigene sowie antigen-antikörper-komplexe mit elisa-tests
ATE354370T1 (de) * 2001-09-27 2007-03-15 Gangagen Inc Inaktivierte immunogene bakterielle ganzzell- zusammensetzungen
CA2461647C (en) * 2001-09-27 2012-01-24 Gangagen, Inc. Lysin-deficient bacteriophages having reduced immunogenicity
EP1437936A4 (en) 2001-09-27 2005-10-12 Pioneer Hi Bred Int PHYTATE POLYNUCLEOTIDES AND METHOD FOR THEIR USE
AU2002330102A1 (en) * 2001-09-28 2003-04-14 Aspenbio, Inc. Bovine pregnancy test
US20030110518A1 (en) * 2001-09-28 2003-06-12 Houseknecht Karen L. Melanocortin-5 receptor sequences and uses thereof
CA2462790A1 (en) 2001-10-04 2003-04-10 Immunex Corporation Ul16 binding protein 4
CA2462950A1 (en) 2001-10-10 2003-04-17 Sugen, Inc. 3-[4-(substituted heterocyclyl)-pyrrol-2-ylmethylidene]-2-indolinone derivatives as kinase inhibitors
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
DE10151511A1 (de) 2001-10-18 2003-05-08 Basf Lynx Bioscience Ag ee3-Proteinfamilie und zugrundeliegende DNA-Sequenzen
US20050221420A1 (en) * 2001-10-22 2005-10-06 Carmen Barske Nogo receptor homologues and their use
GB0126378D0 (en) 2001-11-02 2002-01-02 Oxford Biomedica Ltd Antigen
US20040067512A1 (en) * 2001-11-09 2004-04-08 Neurogenetics, Inc. Single nucleotide polymorphisms and mutations on Alpha-2-Macroglobulin
CA2466443A1 (en) * 2001-11-09 2003-05-15 Neopharm, Inc. Selective treatment of il-13 expressing tumors
WO2003051174A2 (en) * 2001-11-09 2003-06-26 Neurogenetics, Inc. Single nucleotide polymorphisms and mutations on alpha-2-macroglobulin
AU2002356898A1 (en) * 2001-11-15 2003-06-10 Tularik Inc. Gene amplification and overexpression in cancer
US20030099621A1 (en) 2001-11-29 2003-05-29 Robert Chow Stem cell screening and transplantation therapy for HIV infection
EP2002827A2 (en) 2001-12-05 2008-12-17 The Baylor College Of Medicine Methods and compositions for control of bone formation via modulation of sympathetic tone
CN1612941B (zh) * 2001-12-10 2011-11-16 诺瓦提斯公司 基于cntf基因的多态性治疗精神病和精神分裂症的方法
AU2002359697A1 (en) * 2001-12-20 2003-07-09 Tularik Inc. Identification of an amplified gene and target for drug intervention
US20060034829A1 (en) * 2001-12-27 2006-02-16 Gerngross Tillman U Immunoglobulins comprising predominantly a MAN3GLCNAC2 glycoform
US20060024292A1 (en) * 2001-12-27 2006-02-02 Gerngross Tillman U Immunoglobulins comprising predominantly a Gal2GlcNAc2Man3GlcNAc2 glycoform
US20040137440A1 (en) * 2002-01-15 2004-07-15 Biaoyang Lin Androgen regulated nucleic acid molecules and encoded proteins
US7462491B2 (en) * 2002-01-31 2008-12-09 Baylor College Of Medicine Methods and compositions for diagnosis and monitoring of prostate cancer progression by detection of serum caveolin
US7704700B2 (en) * 2002-02-12 2010-04-27 Burnham Institute For Medical Research Methods for determining the prognosis for patients with a prostate neoplastic condition using inhibitor of apoptosis polypeptides
AU2003237779B2 (en) 2002-02-13 2008-06-26 American Diagnostica Inc. Methods for selecting treatment regimens and predicting outcomes in cancer patients
US20060088830A1 (en) * 2002-02-21 2006-04-27 Eastern Virginia Medical School Protein biomarkers that distinguish prostate cancer from non-malignant cells
WO2003072738A2 (en) * 2002-02-22 2003-09-04 Board Of Trustees Of The University Of Illinois Beta chain-associated regulator of apoptosis
WO2003072035A2 (en) 2002-02-22 2003-09-04 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
US7662924B2 (en) * 2002-02-22 2010-02-16 The Board Of Trustees Of The University Of Illinois Beta chain-associated regulator of apoptosis
US7294471B2 (en) * 2002-02-27 2007-11-13 Cskeys, Llc Method for purifying cancer-specific proliferating cell nuclear antigen
EP1480666B1 (en) 2002-03-05 2012-06-13 Ramot at Tel-Aviv University Ltd. Immunizing composition and method for inducing an immune response against the beta-secretase cleavage site of amyloid precursor protein
WO2003079025A2 (en) 2002-03-19 2003-09-25 Novartis Ag Methods for the identification of compounds useful for the suppression of chronic neuropathic pain and compositions thereof
US6974672B2 (en) * 2002-03-19 2005-12-13 Amgen Inc. Gene amplification in cancer
AU2003221841A1 (en) 2002-04-03 2003-10-27 Celltech R And D, Inc. Association of polymorphisms in the sost gene region with bone mineral density
WO2004040398A2 (en) * 2002-05-06 2004-05-13 Dana-Farber Cancer Institute, Inc. Use of a computer to design a molecule
WO2003094841A2 (en) * 2002-05-06 2003-11-20 Functional Genetics, Inc. Mammalian genes involed in rapamycin resistance and tumorgenesis: annexin xiii genes
AU2003239544A1 (en) * 2002-05-24 2003-12-12 Tularik Inc. Amplification and overexpression of oncogenes
EP2305710A3 (en) 2002-06-03 2013-05-29 Genentech, Inc. Synthetic antibody phage libraries
GB0213745D0 (en) 2002-06-14 2002-07-24 Univ Edinburgh Enzyme
AU2003247806B2 (en) 2002-07-08 2009-11-12 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
US20040219609A1 (en) * 2002-07-12 2004-11-04 Day Anthony G. Methods for modulating proteins not previously known as proteases
US20040053399A1 (en) * 2002-07-17 2004-03-18 Rudolf Gilmanshin Methods and compositions for analyzing polymers using chimeric tags
CA2492883C (en) 2002-08-01 2012-10-02 James D. Marks Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
US20050059011A1 (en) * 2002-08-07 2005-03-17 Sin Wun Chey Amplification and overexpression of oncogenes
MXPA05001832A (es) * 2002-08-13 2005-08-16 N Dia Inc Dispositivos y metodos para detectar fluido amniotico en secreciones vaginales.
AU2003268135A1 (en) * 2002-08-15 2004-03-19 Functional Genetics, Inc. Mammalian genes involved in rapamycin resistance and tumorgenesis: rapr6 genes
WO2004020581A2 (en) * 2002-08-15 2004-03-11 Functional Genetics, Inc. Mammalian genes involved in rapamycin resistance and tumorgenesis: rapr7 genes
WO2004016643A2 (en) 2002-08-16 2004-02-26 Yeda Research And Development Co. Ltd. Tumor associated antigen, peptides thereof, and use of same as anti-tumor vaccines
AU2003251702B2 (en) 2002-08-23 2010-06-03 Bayer Schering Pharma Aktiengesellschaft Polypeptide biomarkers for diagnosing alzheimer's disease
US7785608B2 (en) * 2002-08-30 2010-08-31 Wyeth Holdings Corporation Immunogenic compositions for the prevention and treatment of meningococcal disease
NZ538384A (en) 2002-09-06 2009-04-30 Alexion Pharma Inc Treatment for asthma using a compound which binds to or otherwise blocks the generation and/or activity of one or more complement components reptors, such as, C5a receptors
AU2003267096B9 (en) 2002-09-11 2010-11-11 Genentech, Inc. Novel compositions and methods for the treatment of immune related diseases
WO2004024068A2 (en) 2002-09-11 2004-03-25 Genentech, Inc. Novel composition and methods for the treatment of immune related diseases
JP2006521082A (ja) 2002-09-11 2006-09-21 ジェネンテック・インコーポレーテッド 免疫関連疾患の治療のための新規組成物と方法
AU2003291625B2 (en) 2002-09-16 2009-10-08 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
US7094551B2 (en) * 2002-09-17 2006-08-22 Zahradnik Richard J Immunoassays, assay methods, antibodies and method of creating antibodies for detecting FGF-23
AU2003279084A1 (en) 2002-09-25 2004-04-19 Genentech, Inc. Novel compositions and methods for the treatment of psoriasis
JP2006518982A (ja) * 2002-10-02 2006-08-24 エフ．ホフマン−ラ　ロシュ　アーゲー Ｍｈｃｉｉ結合ペプチド
US7432351B1 (en) 2002-10-04 2008-10-07 Mayo Foundation For Medical Education And Research B7-H1 variants
DE60320821D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 2002-10-11 2008-06-19 Sentina Biotechnology Inc
US20080293750A1 (en) * 2002-10-17 2008-11-27 Anna Helgadottir Susceptibility Gene for Myocardial Infarction, Stroke, Paod and Methods of Treatment
JP3447009B1 (ja) * 2002-10-29 2003-09-16 實 平垣 構築物用構成体およびその製造方法
AU2003298607B9 (en) 2002-10-29 2011-08-04 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
WO2004042030A2 (en) 2002-11-01 2004-05-21 Leucadia Technologies, Inc. Displacement sandwich immuno-pcr
EP1581169A4 (en) 2002-11-08 2008-09-17 Genentech Inc COMPOSITIONS AND METHODS FOR TREATING DISEASES RELATED TO NATURAL K CELLS
US20050129711A1 (en) * 2002-11-14 2005-06-16 Janakiraman Ramachandran Incapacitated whole-cell immunogenic bacterial compositions produced by recombinant expression
US7754450B2 (en) * 2002-11-15 2010-07-13 Morphotek, Inc. Methods of generating high-production of antibodies from hybridomas created by in vitro immunization
WO2004047728A2 (en) 2002-11-26 2004-06-10 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
US20040101860A1 (en) * 2002-11-27 2004-05-27 Jones Alison M. Predicting animal performance
US20040259226A1 (en) * 2003-05-30 2004-12-23 Robey W. Wade Monitoring for and detecting microbes used in bioterrorism
WO2004050873A1 (en) * 2002-11-29 2004-06-17 The University Of Hong Kong Genetically modified plants expressing proteinase inhibitors, sapina2a or sapin2b, and methods of use thereof for the inhibition of trypsin-and chymotrypsin-like activities
EP1570075A2 (en) * 2002-12-03 2005-09-07 Aarhus Universitet Method for determing predisposition to manifestation of immune system related diseases
JP2006512076A (ja) * 2002-12-31 2006-04-13 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー イヌ（ｃａｎｉｎｅ）Ｌ−ＰＢＥ配列
AU2003285680A1 (en) * 2002-12-31 2004-07-22 Pharmacia & Upjohn Company Llc Canine dioxin/aryl hydrocarbon receptor sequences
JP2006512075A (ja) * 2002-12-31 2006-04-13 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー イヌｃｙｐ１ａ２配列
US7560272B2 (en) * 2003-01-04 2009-07-14 Inverness Medical Switzerland Gmbh Specimen collection and assay container
JP2006518997A (ja) * 2003-01-21 2006-08-24 ブリストル−マイヤーズ　スクイブ　カンパニー 新規アシルコエンザイムａ：モノアシルグリセロールアシルトランスフェラーゼ−３（ｍｇａｔ３）をコードするポリヌクレオチドおよびその用途
US7449321B2 (en) * 2003-01-22 2008-11-11 National University Of Singapore Molecules, compositions, methods and kits for applications associated with flaviviruses
CA2514839A1 (en) 2003-02-01 2004-08-19 Tanox, Inc. A method for generating high affinity antibodies
WO2004069873A2 (en) 2003-02-06 2004-08-19 Tripep Ab Antigen/antibody or ligand/receptor glycosylated specificity exchangers
US7335359B2 (en) * 2003-02-06 2008-02-26 Tripep Ab Glycosylated specificity exchangers
WO2004071462A2 (en) * 2003-02-12 2004-08-26 Johns Hopkins University Methods and compositions for treatment of viral infections based on tsg101-vps28 interaction
EP1594900A2 (en) * 2003-02-14 2005-11-16 Salmedix, Inc. Compositions and methods for the detection and treatment of methylthioadenosine phosphorylase deficient cancers
GB0304515D0 (en) * 2003-02-27 2003-04-02 Dakocytomation Denmark As Standard
US20040178714A1 (en) * 2003-03-11 2004-09-16 Pan Wun Fang Decorative bulb of a series connected light string
US20040185446A1 (en) * 2003-03-18 2004-09-23 Jones Alison M. Cpn60 targets for quantification of microbial species
US20040185434A1 (en) * 2003-03-21 2004-09-23 Robey W. Wade Detecting microbial contamination in animal by-products
US20040185454A1 (en) * 2003-03-21 2004-09-23 Jones Alison M. Identification and quantification of microbial species in a sample
WO2004087758A2 (en) * 2003-03-26 2004-10-14 Neopharm, Inc. Il 13 receptor alpha 2 antibody and methods of use
JP5392980B2 (ja) * 2003-03-27 2014-01-22 チルドレンズ ホスピタル メディカル センター 早発型の腎尿細管細胞障害を検出するための方法およびキット
BRPI0409459A (pt) * 2003-04-16 2006-05-02 Wyeth Corp novas composições imunogênicas para a prevenção e tratamento de doença meningocócica
US7321065B2 (en) * 2003-04-18 2008-01-22 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof
US7892745B2 (en) * 2003-04-24 2011-02-22 Xdx, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
US20060263813A1 (en) * 2005-05-11 2006-11-23 Expression Diagnostics, Inc. Methods of monitoring functional status of transplants using gene panels
KR100531760B1 (ko) * 2003-04-28 2005-11-29 대한민국(관리부서 : 농림부 국립수의과학검역원) 구제역 바이러스의 감염여부를 진단하는 방법 및 이를구현하기 위한 진단키트
US7892563B2 (en) 2003-05-20 2011-02-22 Wyeth Holdings Corporation Methods for treatment of severe acute respiratory syndrome (SARS)
US20050250094A1 (en) * 2003-05-30 2005-11-10 Nanosphere, Inc. Method for detecting analytes based on evanescent illumination and scatter-based detection of nanoparticle probe complexes
US20040241662A1 (en) * 2003-05-30 2004-12-02 Robey W. Wade Detecting microbial contamination in grain and related products
CA2526080A1 (en) * 2003-05-30 2005-01-06 Genentech, Inc. Polypeptides that bind an anti-tissue factor antibody and uses thereof
US7405274B2 (en) 2003-06-04 2008-07-29 Fibrogen, Inc. Connective tissue growth factor antibodies
AU2004247146A1 (en) * 2003-06-12 2004-12-23 Vaxgen, Inc. HIV-1 envelope glycoproteins having unusual disulfide structure
ES2586401T3 (es) * 2003-06-16 2016-10-14 Ucb Pharma S.A. Anticuerpos específicos para la esclerostina y métodos para aumentar la mineralización ósea
IL156495A0 (en) * 2003-06-17 2004-01-04 Prochon Biotech Ltd Use of fgfr3 antagonists for treating t cell mediated diseases
CA2528529A1 (en) * 2003-06-20 2004-12-29 Amgen Inc. Gene amplification and overexpression in cancer
JP4750024B2 (ja) 2003-06-20 2011-08-17 プロテイン サイエンシーズ コーポレイション Ｓａｒｓの免疫原を発現するベクター、そのようなベクター又はその発現産物を含有する組成物、並びにその作製及び使用の方法及びアッセイ
GB0315991D0 (en) * 2003-07-08 2003-08-13 Dakocytomation Denmark As Standard
PT2784084T (pt) 2003-07-08 2019-10-01 Genentech Inc Anticorpos antagonistas contra polipéptidos heterólogos il-17a/f
US20050014734A1 (en) * 2003-07-18 2005-01-20 Genovate Biotechnology Co., Ltd. Modulation of interleukin-10 by DHEA
JP2007500132A (ja) 2003-07-25 2007-01-11 アムジェン インコーポレイテッド Ｌｄｃａｍのアンタゴニストおよびアゴニスト、並びにその使用法
WO2005012537A2 (en) * 2003-07-25 2005-02-10 Genvec, Inc. Adenoviral vector-based vaccines
GB0317592D0 (en) * 2003-07-26 2003-08-27 Astrazeneca Ab Method
US20050106667A1 (en) 2003-08-01 2005-05-19 Genentech, Inc Binding polypeptides with restricted diversity sequences
US7476399B2 (en) 2003-08-06 2009-01-13 Senomyx Inc. Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof
WO2005019258A2 (en) 2003-08-11 2005-03-03 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
WO2005018571A2 (en) 2003-08-20 2005-03-03 University Of Miami Compositions and methods for treating inflammatory lung disease
US20050048589A1 (en) * 2003-08-25 2005-03-03 Moncef Jendoubi Lung cancer specific gene products: their coding sequence, their antibodies and their use in diagnostic, therapeutic and disease management of lung cancer
US7517495B2 (en) * 2003-08-25 2009-04-14 Inverness Medical Switzerland Gmbh Biological specimen collection and analysis system
CA2536873C (en) 2003-08-29 2019-09-10 Dyax Corp. Poly-pegylated protease inhibitors
US7604994B2 (en) * 2003-09-03 2009-10-20 Morphotek, Inc. Genetically altered antibody-producing cell lines with improved antibody characteristics
MXPA06002563A (es) * 2003-09-05 2006-06-20 Scripps Research Inst Deteccion de productos de ozonacion de colesterol.
US20050214279A1 (en) * 2003-09-19 2005-09-29 Silverstein Samuel C Methods for stimulating human leukocytes to kill bacteria, yeast and fungi in biofilms that have formed in/on prosthetic devices, catheters, tissues and organs in vivo
US20070111209A1 (en) * 2003-09-19 2007-05-17 Soley Bjornsdottir Inversion on chromosome 8p23 is a risk factor for anxiety disorders, depression and bipolar disorders
US20050069958A1 (en) * 2003-09-26 2005-03-31 Mills Rhonda A. Method for simultaneous evaluation of a sample containing a cellular target and a soluble analyte
US20050069546A1 (en) 2003-09-30 2005-03-31 Yaron Ilan Educated NKT cells and their uses in the treatment of immune-related disorders
IL158287A0 (en) 2003-10-07 2004-05-12 Yeda Res & Dev Antibodies to nik, their preparation and use
CA2542542C (en) 2003-10-21 2015-09-15 Orion Genomics Llc Method of detecting a quantity of methylation at a locus
AU2004293471C1 (en) 2003-11-25 2011-02-24 The Government Of The United States, As Represented By The Secretary Of Health And Human Services Mutated anti-CD22 antibodies and immunoconjugates
WO2005062048A1 (de) 2003-12-01 2005-07-07 Dade Behring Marburg Gmbh Homogenes nachweisverfahren
US20050118727A1 (en) * 2003-12-01 2005-06-02 Carsten Schelp Conjugates and their use in detection methods
CA2550900A1 (en) 2003-12-23 2005-07-07 Mount Sinai Hospital Methods for detecting markers associated with endometrial disease or phase
PT2805728T (pt) 2003-12-23 2020-04-08 Genentech Inc Novos anticorpos anti-il13 e o uso dos mesmos
US7150995B2 (en) * 2004-01-16 2006-12-19 Metrika, Inc. Methods and systems for point of care bodily fluid analysis
US20060147946A1 (en) * 2004-01-27 2006-07-06 Pinchas Akiva Novel calcium channel variants and methods of use thereof
US8158362B2 (en) * 2005-03-30 2012-04-17 Decode Genetics Ehf. Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype
US20100216863A1 (en) * 2004-01-30 2010-08-26 Decode Genetics Ehf. Susceptibility Gene for Myocardial Infarction, Stroke, and PAOD; Methods of Treatment
US20050271650A1 (en) * 2004-02-17 2005-12-08 Cellmatrix, Inc. Method and composition for angiogenesis inhibition
US20060122377A1 (en) 2004-02-19 2006-06-08 Genentech, Inc. CDR-repaired antibodies
US7604956B2 (en) * 2004-03-01 2009-10-20 Biotraces, Inc. Supersensitive immunoassays
KR20070002044A (ko) * 2004-03-05 2007-01-04 뿌리마하무가부시끼가이샤 알레르겐의 검출방법
US20050227370A1 (en) * 2004-03-08 2005-10-13 Ramel Urs A Body fluid analyte meter & cartridge system for performing combined general chemical and specific binding assays
US9498484B2 (en) 2004-03-12 2016-11-22 Intercept Pharmaceuticals, Inc. Treatment of fibrosis using FXR ligands
JP2007529758A (ja) * 2004-03-19 2007-10-25 ユー．エス． ジェノミクス， インコーポレイテッド 単一分子の検出のための組成物および方法
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
US7396654B2 (en) 2004-04-15 2008-07-08 University Of Florida Research Foundation, Inc. Neural proteins as biomarkers for traumatic brain injury
CN1997893A (zh) * 2004-04-16 2007-07-11 健泰科生物技术公司 抗体测定法
WO2005115394A2 (en) * 2004-04-20 2005-12-08 New York University School Of Medicine Prenyl-electrostatic switch, and methods of use
WO2005107796A2 (en) 2004-04-23 2005-11-17 Pharmacia & Upjohn Company, Llc Cellular permissivity factor for viruses, and uses thereof
AU2005243193B2 (en) 2004-04-29 2011-01-27 Otsuka Pharmaceutical Co., Ltd. Antibodies specific for glycoprotein VI and methods of producing these antibodies
AU2005247332A1 (en) 2004-04-30 2005-12-08 Corthera, Inc. Methods and compositions for control of fetal growth via modulation of relaxin
US20050272101A1 (en) * 2004-06-07 2005-12-08 Prasad Devarajan Method for the early detection of renal injury
US7939251B2 (en) 2004-05-06 2011-05-10 Roche Molecular Systems, Inc. SENP1 as a marker for cancer
UY28886A1 (es) 2004-05-10 2005-12-30 Boehringer Ingelheim Int Anticuerpos que consisten en polipéptidos y derivados conprendiendo tres secuencias conteniendo respectivamente los siguientes números de seq. id: 1-3 y 4-6; 7-9 y 10-12 y 13-15 ó 16-18
ES2655833T3 (es) 2004-05-11 2018-02-21 AbGenomics Coöperatief U.A. Epítopos que inducen la muerte de células T
EP1769243A2 (en) * 2004-05-15 2007-04-04 Genentech, Inc. Cross-screening system and methods for detecting a molecule having binding affinity for a target molecule
US7504205B2 (en) * 2004-05-17 2009-03-17 The Burnham Institute Uncharacterized ORF3 in SARS-coronavirus is a cyclic-AMP-dependent kinase and a target for SARS therapy
US7604947B2 (en) * 2004-06-09 2009-10-20 Cornell Research Foundation, Inc. Detection and modulation of cancer stem cells
US20060003410A1 (en) 2004-06-10 2006-01-05 Lee-Ming Chuang Prostaglandin reductase
DK1766077T3 (da) 2004-06-21 2012-07-16 Univ Leland Stanford Junior Differentielt udtrykte gener og veje i bipolar forstyrrelse og/eller alvorlig depressiv forstyrrelse
US8034553B2 (en) 2004-06-24 2011-10-11 Kimberly-Clark Worldwide, Inc. Biomarkers for wound healing
US7973134B2 (en) * 2004-07-07 2011-07-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in anaplastic large cell lymphoma signaling pathways
ATE540973T1 (de) 2004-07-22 2012-01-15 Five Prime Therapeutics Inc Zusammensetzungen und verfahren zur verwendung von mgd-cdf zur krankheitsbehandlung
US7342093B2 (en) 2004-07-23 2008-03-11 University Of Massachusetts Compounds that inhibit Hsp90 protein-protein interactions with IAP proteins
US20060024744A1 (en) * 2004-07-28 2006-02-02 Mills Rhonda A Methods for substantially simultaneous evaluation of a sample containing a cellular target and a soluble analyte
US7510858B2 (en) * 2004-08-02 2009-03-31 Janssen Pharmaceutica N.V. IRAK 1c splice variant and its use
WO2006023312A2 (en) * 2004-08-20 2006-03-02 Carl Deirmengian Diagnostic assay for source of inflammation
US7893197B2 (en) * 2004-08-25 2011-02-22 Janssen Pharmaceutica N.V. Relaxin-3 chimeric polypeptides and their preparation and use
EP1784493A2 (en) * 2004-09-01 2007-05-16 The Government of the United States of America as Represented by The Department of Health and Human Services Adenoviral vectors able to transduce apcs, potential use in immune response generation
US7645575B2 (en) * 2004-09-08 2010-01-12 Xdx, Inc. Genes useful for diagnosing and monitoring inflammation related disorders
FI20041204A0 (fi) 2004-09-16 2004-09-16 Riikka Lund Menetelmät immuunivälitteisiin sairauksiin liittyvien uusien kohdegeenien hyödyntämiseksi
GB0421639D0 (en) 2004-09-29 2004-10-27 Proteome Sciences Plc Methods and compositions relating to alzheimer's disease
US7935790B2 (en) * 2004-10-04 2011-05-03 Cell Singaling Technology, Inc. Reagents for the detection of protein phosphorylation in T-cell receptor signaling pathways
EP1807106A2 (en) * 2004-10-05 2007-07-18 Oregon Health and Science University Compositions and methods for treating disease
HUE039237T2 (hu) * 2004-10-06 2018-12-28 Mayo Found Medical Education & Res B7-H1 és PD-1 vesesejt karcinoma kezelésében
US8969291B2 (en) 2004-10-08 2015-03-03 Enzo Therapeutics, Inc. Methods for decreasing leptin levels or activity for treating inflammation
WO2006047417A2 (en) 2004-10-21 2006-05-04 University Of Florida Research Foundation, Inc. Detection of cannabinoid receptor biomarkers and uses thereof
EP2586456B1 (en) 2004-10-29 2016-01-20 ratiopharm GmbH Remodeling and glycopegylation of fibroblast growth factor (FGF)
DE602005023529D1 (de) * 2004-11-03 2010-10-21 Iris Molecular Diagnostics Inc Homogener nachweis von analyten
EP2302078B1 (en) * 2004-11-03 2015-07-15 Iris Molecular Diagnostics, Inc. Microbubbles for affinity concentration
AU2005302083A1 (en) * 2004-11-04 2006-05-11 Fibron Limited Treatment of B-cell malignancies
JP5341350B2 (ja) 2004-11-16 2013-11-13 トラスティーズ オブ ボストン ユニバーシティ 高血圧および血管新生におけるエンドセリン−１／アンジオテンシンｉｉ二重レセプター（ｄｅａｒ）の役割
US20070207496A1 (en) * 2004-11-19 2007-09-06 Larsen Oeistein Diagnostic control system
WO2006068768A2 (en) 2004-11-24 2006-06-29 Hanna Skubatch Methods and compositions for treating conditions
US7608277B2 (en) * 2004-12-01 2009-10-27 Gene Therapy Systems, Inc. Tuberculosis nucleic acids, polypeptides and immunogenic compositions
ES2336345T3 (es) * 2004-12-20 2010-04-12 Antibodyshop A/S Determinacion de lipocalina asociada a gelatinasa de neutrofilos (ngal) como marcador de diagnostico para trastornos renales.
US7807789B2 (en) * 2004-12-21 2010-10-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in EGFR-signaling pathways
SG176509A1 (en) 2004-12-22 2011-12-29 Genentech Inc Methods for producing soluble multi-membrane-spanning proteins
CA2531616A1 (en) * 2004-12-28 2006-06-28 Kabushiki Kaisha Kobe Seiko Sho (Kobe Steel, Ltd.) High strength thin steel sheet having high hydrogen embrittlement resisting property and high workability
US8697674B2 (en) * 2004-12-29 2014-04-15 Naturon, Inc. Xanthurenic acid derivative pharmaceutical compositions and methods related thereto
EP1997890A1 (en) 2004-12-30 2008-12-03 Agency for Science, Technology and Research Chinese hamster apoptosis-related genes
EP1850866A4 (en) 2005-01-27 2009-07-08 Univ California MONOCLONAL THERAPEUTIC ANTIBODIES FOR THE NEUTRALIZATION OF BOTULIN NEUROTOXINES
ATE408828T1 (de) * 2005-02-16 2008-10-15 Dana Farber Cancer Inst Inc Verfahren zur erkennung eines ovarialkarzinoms
US20080213237A1 (en) * 2005-03-10 2008-09-04 Hadasit Medical Research Services And Development Ltd. Antigen Specific Lymphocytes, Compositions Thereof, and Methods for Isolation and Preparation Thereof
EP2481424A1 (en) 2005-03-19 2012-08-01 Medical Research Council Improvements in or relating to treatment and prevention of hepatitis C viral infections
US20070092886A1 (en) * 2005-03-22 2007-04-26 Raymond Tabibiazar Methods and compositions for diagnosis, monitoring and development of therapeutics for treatment of atherosclerotic disease
AU2006226733C9 (en) 2005-03-23 2019-03-14 Genmab A/S Antibodies against CD38 for treatment of multiple myeloma
US8323645B2 (en) 2005-03-24 2012-12-04 Millennium Pharmaceuticals, Inc. Antibodies that bind OV064 and methods of use therefor
US20070037232A1 (en) * 2005-03-31 2007-02-15 Barasch Jonathan M Detection of NGAL in chronic renal disease
US8048638B2 (en) * 2005-04-01 2011-11-01 University Of Florida Research Foundation, Inc. Biomarkers of liver injury
EP1874958B1 (en) 2005-04-01 2019-03-27 University of Florida Research Foundation, Incorporated Biomarkers of liver injury
LT3264094T (lt) 2005-04-04 2021-04-12 Biogen Ma Inc. Imuninio atsako į terapijos agentą įvertinimo būdai
US9187546B2 (en) 2005-04-08 2015-11-17 Novo Nordisk A/S Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
LT3321359T (lt) 2005-04-11 2021-05-10 Horizon Pharma Rheumatology Llc Urato oksidazės variantinės formos ir jų panaudojimas
US20090099340A1 (en) * 2007-10-12 2009-04-16 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
CA2606721A1 (en) * 2005-05-02 2006-11-09 The Curators Of The University Of Missouri Detection of carbohydrate biomarkers
US8003108B2 (en) 2005-05-03 2011-08-23 Amgen Inc. Sclerostin epitopes
US7592429B2 (en) * 2005-05-03 2009-09-22 Ucb Sa Sclerostin-binding antibody
WO2006125021A2 (en) * 2005-05-16 2006-11-23 Dana Farber Cancer Institute, Inc. Fibrinogen alpha and hemoglobin polypeptides as cancer markers
BRPI0610794A2 (pt) 2005-05-18 2010-11-09 Decore Genetics Ehf métodos para diagnosticar uma susceptibilidade a um cáncer e para predizer um risco aumentado de cáncer, kit para ensaiar uma amostra de um indivìduo para detectar uma susceptibilidade a um cáncer, e, métodos para diagnosticar um risco aumentado de cáncer e para diagnosticar um cáncer associado com chr8q24.21
RU2413947C2 (ru) * 2005-05-23 2011-03-10 Фадиа Аб Способы и устройства для двухэтапного латерального проточного анализа
US7968697B2 (en) * 2005-05-25 2011-06-28 Chrontech Pharma Ab Hepatitis C virus non-structural NS3/4A fusion gene
US8652465B2 (en) 2005-06-08 2014-02-18 Emory University Methods and compositions for the treatment of persistent infections
CA2612475C (en) * 2005-06-20 2015-07-28 Decode Genetics Ehf. Genetic variants in the tcf7l2 gene as diagnostic markers for risk of type 2 diabetes mellitus
US7482124B2 (en) * 2005-07-08 2009-01-27 Bristol-Myers Squibb Company Method of identifying a PPARgamma-agonist compound having a decreased likelihood of inducing dose-dependent peripheral edema
US7906297B2 (en) 2005-07-20 2011-03-15 Cell Signaling Technology, Inc. Reagents for the detection of phosphorylated ATR kinase (Ser 428) and uses thereof
JP2009504659A (ja) * 2005-08-08 2009-02-05 オンコノン・リミテッド・ライアビリティ・カンパニー 抗体組成物、腫瘍性疾患の処置方法、および受胎能の調節方法
US20070202512A1 (en) * 2005-08-19 2007-08-30 Bristol-Myers Squibb Company Human single nucleotide polymorphisms associated with dose-dependent weight gain and methods of use thereof
BRPI0617057A2 (pt) 2005-08-30 2011-07-12 Univ Miami anticorpo isolado, toxina especìfica para receptor de fator de necrose tumoral 25 (tnfr25), método para ativar o receptor de fator de necrose tumoral 25 (tnfr25), método para inibir a sinalização do receptor de fator de necrose tumoral 25 (tnfr25) numa célula, vacina antitumoral, método para imunizar um paciente contra tumor, método para tratar cáncer num paciente, método para tratar e/ou prevenir inflamação intestinal, composição terapêutica para a facilitação de um transplante de órgão, método para transplantar um tecido de um doador para um hospedeiro, método para inibir a expressão clonal de uma população de células t cd8 cognatas, método para tratar e/ou prevenir inflamação pulmonar, antagonista de tnfr25 isolado, composição e vetor de expressão
US20100151495A9 (en) * 2005-08-31 2010-06-17 Cell Signaling Technolgy, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
EP1934867A2 (en) * 2005-08-31 2008-06-25 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in leukemia signaling pathways
WO2007027867A2 (en) 2005-08-31 2007-03-08 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
WO2007030560A2 (en) * 2005-09-08 2007-03-15 Philadelphia Health & Education Corporation, D/B/A Drexel University College Of Medicine Identification of modulators of serine protease inhibitor kazal and their use as anti-cancer and anti-viral agents
AU2005336263A1 (en) * 2005-09-09 2007-03-15 Glycofi, Inc. Immunoglobulin comprising predominantly a man7GlcNAc2, Man8GlcNAc2 glycoform
US7611834B2 (en) * 2005-09-30 2009-11-03 Sandia Corporation Methods and devices for protein assays
IL172297A (en) 2005-10-03 2016-03-31 Compugen Ltd Soluble vegfr-1 variants for the diagnosis of preeclampsia
US8119358B2 (en) * 2005-10-11 2012-02-21 Tethys Bioscience, Inc. Diabetes-related biomarkers and methods of use thereof
EP2177908A3 (en) 2005-10-11 2010-05-19 Tethys Bioscience, Inc. Diabetes-associated markers and methods of use thereof
US20080090304A1 (en) * 2006-10-13 2008-04-17 Barasch Jonathan Matthew Diagnosis and monitoring of chronic renal disease using ngal
WO2007053524A2 (en) * 2005-10-28 2007-05-10 The Florida International University Board Of Trustees Horse: human chimeric antibodies
US20090074720A1 (en) * 2005-10-28 2009-03-19 Sabbadini Roger A Methods for decreasing immune response and treating immune conditions
US20080213274A1 (en) * 2005-10-28 2008-09-04 Sabbadini Roger A Compositions and methods for the treatment and prevention of fibrotic, inflammatory, and neovascularization conditions of the eye
EP1948687A2 (en) * 2005-10-31 2008-07-30 Janssen Pharmaceutica N.V. A polypeptide complex of trpm8 and calmodulin and its uses thereof
EP1948674A4 (en) 2005-11-02 2009-02-04 Protiva Biotherapeutics Inc MODIFIED SIRNA MOLECULES AND APPLICATIONS THEREOF
MX360959B (es) 2005-11-04 2018-11-23 Genentech Inc Uso de inhibidores de la vía del complemento para tratar enfermedades oculares.
BRPI0618338A2 (pt) 2005-11-07 2011-08-23 Scripps Resarch Inst uso de inibidor de sinalização de fator tecidual, método para identificar um agente que inibe a sinalização de tf/viia, composições farmacêuticas e kit
WO2007056411A2 (en) * 2005-11-08 2007-05-18 Genentech, Inc. Method of producing pan-specific antibodies
UA96139C2 (uk) 2005-11-08 2011-10-10 Дженентек, Інк. Антитіло до нейропіліну-1 (nrp1)
ES2534672T3 (es) 2005-11-12 2015-04-27 The Board Of Trustees Of The Leland Métodos relacionados con FGF2 para diagnosticar y tratar la depresión
WO2007057395A2 (en) 2005-11-16 2007-05-24 Novartis Ag Biomarkers for anti-nogo-a antibody treatment in spinal cord injury
DK1948798T3 (en) 2005-11-18 2015-07-06 Glenmark Pharmaceuticals Sa The anti-alpha2-integrin antibodies and uses thereof
ES2409835T3 (es) 2005-11-28 2013-06-28 Zymogenetics, Inc. Antagonistas de IL-21
DK2468901T3 (en) 2005-11-29 2017-07-17 Cambridge Entpr Ltd Markers for breast cancer
US7822474B2 (en) * 2005-11-30 2010-10-26 Cedars-Sinai Medical Center Methods for the prediction of arrhythmias and prevention of sudden cardiac death
EP2623516B1 (en) 2005-12-02 2015-07-15 Genentech, Inc. Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling involving antibodies that bind to il-22 and il-22r
US20070134814A1 (en) * 2005-12-09 2007-06-14 Kajander E O Methods and compositions for the detection of calcifying nano-particles, identification and quantification of associated proteins thereon, and correlation to disease
US9347945B2 (en) 2005-12-22 2016-05-24 Abbott Molecular Inc. Methods and marker combinations for screening for predisposition to lung cancer
CA2634797A1 (en) 2005-12-22 2007-07-05 Abbott Laboratories Methods and marker combinations for screening for predisposition to lung cancer
WO2007082154A2 (en) * 2006-01-05 2007-07-19 Mayo Foundation For Medical Education And Research B7-h1 and b7-h4 in cancer
WO2007082144A2 (en) * 2006-01-05 2007-07-19 Mayo Foundation For Medical Education And Research B7-h1 and survivin in cancer
CN101401001A (zh) * 2006-01-12 2009-04-01 詹森药业有限公司 分泌性白细胞蛋白酶抑制剂通过糜酶的加工
WO2007084321A2 (en) 2006-01-12 2007-07-26 Alexion Pharmaceuticals, Inc. Antibodies to ox-2/cd200 and uses thereof
US20100184021A1 (en) 2006-01-16 2010-07-22 Compugen Ltd. Novel nucleotide and amino acid sequences, and methods of use thereof for diagnosis
EP3936621A1 (en) 2006-01-20 2022-01-12 Cell Signaling Technology, Inc. Translocation and mutant ros kinase in human non-small cell lung carcinoma
US20120208824A1 (en) 2006-01-20 2012-08-16 Cell Signaling Technology, Inc. ROS Kinase in Lung Cancer
CN101505780B (zh) 2006-02-22 2017-06-13 朱正崙 发育相关疾病的治疗
WO2007100580A2 (en) * 2006-02-22 2007-09-07 The Texas A & M University System Antibodies recognizing a highly expressed putative antigen of ca-mrsa and methods of use
PL2676967T3 (pl) 2006-02-28 2019-12-31 Biogen Ma Inc. Metody leczenia chorób zapalnych i autoimmunologicznych za pomocą natalizumabu
EP3360900A1 (en) 2006-03-03 2018-08-15 Biogen MA Inc. Methods of treating inflammatory and autoimmune diseases with natalizumab
EP2005185B1 (en) 2006-03-22 2010-10-20 Viral Logic Systems Technology Corp. Methods for identifying polypeptide targets
US8129334B2 (en) 2006-03-31 2012-03-06 The Regents Of The University Of California Methods and compositions for treating neurodegenerative disorders and Alzheimer'S disease and improving normal memory
EP2007909A4 (en) * 2006-04-07 2011-01-26 Xdx Inc EXPRESSION OF NUCLEIC ACID IN RESPONSE TO STEROIDS AND PREDICTION OF DISEASE ACTIVITY
BRPI0709481A2 (pt) * 2006-04-07 2011-07-19 Government Of The Us Secretary Dept Of Health And Human Services anticorpo monoclonal isolado, anticorpo monoclonal humano isolado, composição farmacêutica, anticorpo anti-igf-i e anti-igf-ii recombinante isolado ou fragmento de ligação ao antìgeno do mesmo, método para detectar o fator i e o fator ii de crescimento insulina humana em uma amostra, método para dectetar o fator i de crescimento insulina humana em uma amostra, ácido nucléico isolado, célula recombinante , célula hospedeira ,método para preparar um anticorpo, método para preparar um anticorpo, método para tratar uma doença neoplásica em um indivìduo mamìfero, método para diagnosticar doença neoplásica em um indivìduo mamìfero e método para classificar um composto candidato a fármaco
ES2532804T3 (es) * 2006-04-12 2015-03-31 Crealta Pharmaceuticals Llc Purificación de proteínas con tensioactivo catiónico
PL2450437T3 (pl) 2006-04-14 2017-12-29 Cell Signaling Technology Inc Defekty genu i zmutowana kinaza ALK w ludzkich guzach litych
WO2007124361A2 (en) * 2006-04-20 2007-11-01 Mayo Foundation For Medical Education And Research Soluble b7-h1
US8148536B2 (en) 2006-04-21 2012-04-03 Senomyx, Inc. Comestible compositions comprising high potency savory flavorants, and processes for producing them
US20090298093A1 (en) * 2006-04-27 2009-12-03 Roberto Polakiewicz Reagents for the Detection of Protein Phosphorylation in ATM & ATR Kinase Signaling Pathways
EP2016097A2 (en) 2006-05-04 2009-01-21 Genentech, Inc. Methods and compositions relating to zpa polypeptides
KR20090034811A (ko) * 2006-05-09 2009-04-08 무스크 파운데이션 포 리서치 디벨롭먼트 프로테아제 및 프로테아제 저해제 혈장 프로파일링에 의해 확장기 심부전을 검출하는 방법
CA2652570A1 (en) * 2006-05-15 2007-11-22 Viral Logic Systems Technology Corp. Cd47 related compositions and methods for treating immunological diseases and disorders
US8377448B2 (en) * 2006-05-15 2013-02-19 The Board Of Trustees Of The Leland Standford Junior University CD47 related compositions and methods for treating immunological diseases and disorders
US7745584B2 (en) * 2006-05-22 2010-06-29 California Institute Of Technology Antibodies to sulfated carbohydrates
US20100196336A1 (en) 2006-05-23 2010-08-05 Dongsu Park Modified dendritic cells having enhanced survival and immunogenicity and related compositions and methods
EP1862538A1 (en) * 2006-05-29 2007-12-05 IMBA-Institut für Molekulare Biotechnologie GmbH siRNA kinase and methods of use
ES2379603T3 (es) 2006-05-30 2012-04-27 Antibodyshop A/S Métodos para la evaluación rápida de la gravedad de un traumatismo
US7862812B2 (en) * 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
EP2924440A3 (en) 2006-06-07 2016-03-09 Health Diagnostic Laboratory, Inc. Markers associated with arteriovascular events and methods of use thereof
WO2007144893A2 (en) * 2006-06-15 2007-12-21 Fibron Ltd. Antibodies blocking fibroblast growth factor receptor activation and methods of use thereof
AU2007260817A1 (en) 2006-06-23 2007-12-27 Myriad Genetics, Inc. DPYD gene variants and use thereof
PT2193801E (pt) 2006-06-28 2012-02-28 Yeda Res & Dev Caspase-8 e tratamento de inflamação, infecção e cicatrização de ferida
US7572618B2 (en) 2006-06-30 2009-08-11 Bristol-Myers Squibb Company Polynucleotides encoding novel PCSK9 variants
US20080004410A1 (en) * 2006-06-30 2008-01-03 Yu-Chin Lai Hydrophilic macromonomers having alpha,beta-conjugated carboxylic terminal group and medical devices incorporating same
JP2009544013A (ja) * 2006-07-11 2009-12-10 エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント プロテアーゼおよびプロテアーゼ阻害因子のプロファイリングによる心筋梗塞後の心不全の予測
MY150687A (en) 2006-07-21 2014-02-28 Femalon S P R L Assay and kit for predicting implantation success in assisted fertilisation
ATE465179T1 (de) 2006-07-24 2010-05-15 Pasteur Institut Antikörper, antikörperfragmente und scfv die an posttranslational modifizierte neurotrophine binden
WO2008017306A1 (en) * 2006-08-07 2008-02-14 Antibodyshop A/S Diagnostic test to exclude significant renal injury
WO2008021954A2 (en) * 2006-08-09 2008-02-21 Biogen Idec Ma Inc. Method for distribution of a drug
US7939636B2 (en) * 2006-08-11 2011-05-10 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in c-Src signaling pathways
US7993832B2 (en) * 2006-08-14 2011-08-09 Xdx, Inc. Methods and compositions for diagnosing and monitoring the status of transplant rejection and immune disorders
US20090258442A1 (en) * 2006-08-31 2009-10-15 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
US20100267052A1 (en) * 2006-09-01 2010-10-21 American Type Culture Collection Compositions and methods for diagnosis and treatment of type 2 diabetes
US7951776B2 (en) * 2006-09-01 2011-05-31 American Type Culture Collection Methods for treatment of type 1 diabetes
US20080300170A1 (en) * 2006-09-01 2008-12-04 Cohava Gelber Compositions and methods for diagnosis and treatment for type 2 diabetes
US20090203602A1 (en) * 2006-09-01 2009-08-13 Cohava Gelber Compositions and methods for diagnosis and treatment of type 2 diabetes
US7569396B1 (en) 2006-09-08 2009-08-04 Purplecow Llc Caffeine detection using internally referenced competitive assays
EP2066812A4 (en) 2006-09-21 2010-04-28 Univ Rochester COMPOSITIONS AND METHODS RELATED TO PROTEIN SHIFT THERAPY FOR MYOTONE DYSTROPHY
AU2007302448C1 (en) 2006-09-26 2019-02-14 Genmab A/S Combination treatment of CD38-expressing tumors
KR101551984B1 (ko) 2006-10-04 2015-09-09 제넨테크, 인크. Ｖｅｇｆ용 ｅｌｉｓａ
JP5518479B2 (ja) * 2006-10-25 2014-06-11 ザ ロックフェラー ユニヴァーシティ Ａβ関連障害の処置のための方法およびその組成物
PT2087002E (pt) * 2006-10-27 2014-11-26 Lpath Inc Composições e métodos para a ligação de esfingosina-1- fosfato
CN101687031B (zh) 2006-10-27 2014-05-14 勒帕斯公司 用于治疗眼疾和眼病的组合物及方法
EP2087152B1 (en) 2006-10-27 2015-03-11 Walfish, Paul Endometrial biomarkers
US20080125368A1 (en) * 2006-10-31 2008-05-29 Imperial Innovations Limited Methods
US20100104572A1 (en) * 2006-11-02 2010-04-29 Sylvie Luria Methods for screening for therapeutic molecules and use of the molecules therefrom
TW201534620A (zh) 2006-11-02 2015-09-16 Genentech Inc 人類化之抗-因子ｄ抗體及其用途
EP2102367A2 (en) * 2006-11-09 2009-09-23 XDX, Inc. Methods for diagnosing and monitoring the status of systemic lupus erythematosus
EP2460828A3 (en) * 2006-11-10 2012-08-08 UCB Pharma, S.A. Antibodies and diagnostics
EP2423226A3 (en) * 2006-11-10 2012-05-30 Amgen Inc. Antibody-based diagnostics and therapeutics
US20080112847A1 (en) * 2006-11-15 2008-05-15 Nancy Yu Chen Collecting and testing device and method of use
WO2008064040A2 (en) * 2006-11-22 2008-05-29 The Board Of Regents Of The University Of Texas System Methods and compositions using chelator-antibody conjugates
US20100086921A1 (en) * 2006-11-30 2010-04-08 Valgerdur Steinthorsdottir Genetic susceptibility variants of type 2 diabetes mellitus
WO2008066498A1 (en) 2006-12-01 2008-06-05 Agency For Science, Technology And Research Cancer-related protein kinases
BRPI0720116B8 (pt) * 2006-12-05 2021-07-27 Decode Genetics Ehf método para determinar uma suscetibilidade à arritmia cardíaca ou acidente vascular cerebral em um indivíduo humano, uso de uma sonda de oligonucleotídeo, e, aparelho para determinar um indicador genético para a arritmia cardíaca e/ou acidente vascular cerebral em um indivíduo humano
AR064388A1 (es) 2006-12-18 2009-04-01 Genentech Inc Anticuerpos antagonistas anti- notch3 y su uso en la prevencion y el tratamiento de enfermedades relacionadas con el receptor notch3
US20090186034A1 (en) * 2006-12-19 2009-07-23 Genetech, Inc. Gene expression markers for inflammatory bowel disease
AR064642A1 (es) * 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
WO2008094370A2 (en) 2006-12-22 2008-08-07 University Of Utah Research Foundation Method of detecting ocular diseases and pathologic conditions and treatment of same
US20080171344A1 (en) * 2006-12-22 2008-07-17 Kapsner Kenneth P Methods, Kits and Materials for Diagnosing Disease States by Measuring Isoforms or Proforms of Myeloperoxidase
US7989173B2 (en) 2006-12-27 2011-08-02 The Johns Hopkins University Detection and diagnosis of inflammatory disorders
US20090142342A1 (en) * 2006-12-27 2009-06-04 Johns Hopkins University B7-h4 receptor agonist compositions and methods for treating inflammation and auto-immune diseases
WO2008083239A2 (en) * 2006-12-27 2008-07-10 The Johns Hopkins University Compositions and methods for stimulating an immune response
WO2008085895A2 (en) * 2007-01-04 2008-07-17 Musc Foundation For Research Development Predicting atrial fibrillation recurrence by protease and protease inhibitor profiling
WO2008085857A2 (en) 2007-01-04 2008-07-17 Children's Hospital Medical Center Processing text with domain-specific spreading activation methods
PE20130588A1 (es) * 2007-02-02 2013-05-21 Amgen Inc Hepcidina, antagonistas de la hepcidina y metodos de uso
IN2009DN05722A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2007-02-07 2015-07-24 Decode Genetics Ehf
EA022610B1 (ru) * 2007-02-21 2016-02-29 Декоуд Дженетикс Ехф Способ определения предрасположенности к сердечно-сосудистым заболеваниям с применением полиморфных маркеров
US20090081659A1 (en) 2007-03-07 2009-03-26 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
CN101680903A (zh) * 2007-03-21 2010-03-24 比奥波托诊断股份公司 肾损伤的诊断试验
US7960139B2 (en) 2007-03-23 2011-06-14 Academia Sinica Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
US20090068684A1 (en) * 2007-03-26 2009-03-12 Cell Signaling Technology, Inc. Serine and threoninephosphorylation sites
WO2008118324A2 (en) 2007-03-26 2008-10-02 Macrogenics, Inc. Composition and method of treating cancer with an anti-uroplakin ib antibody
US20090092631A1 (en) * 2007-03-26 2009-04-09 Tripep Ab Glycosylated specificity exchangers that induce an antibody dependent cellular cytotoxicity (adcc) response
EP2137324A2 (en) * 2007-03-26 2009-12-30 Decode Genetics EHF Genetic variants on chr2 and chr16 as markers for use in breast cancer risk assessment, diagnosis, prognosis and treatment
US20100105571A1 (en) 2007-03-27 2010-04-29 Carl Arne Krister Borrebaeck Protein Signature/Markers for the Detection of Adenocarcinoma
US20080238709A1 (en) * 2007-03-28 2008-10-02 Faramarz Vaziri One-way communication apparatus with dynamic key generation
WO2008120202A2 (en) 2007-03-29 2008-10-09 Technion Research & Development Foundation Ltd. Antibodies, methods and kits for diagnosing and treating melanoma
ATE501280T1 (de) * 2007-04-04 2011-03-15 Chimera Biotec Gmbh Verfahren zum nachweis eines analyten in einer biologischen matrix
EP2131834A2 (en) * 2007-04-11 2009-12-16 Alcon Research, Ltd. Use of an inhibitor of tnfa plus an antihistamine to treat allergic rhinitis and allergic conjunctivitis
US20090182035A1 (en) * 2007-04-11 2009-07-16 Alcon Research, Ltd. Use of a combination of olopatadine and cilomilast to treat non-infectious rhinitis and allergic conjunctivitis
DK2147315T3 (da) 2007-04-18 2013-09-23 Tethys Bioscience Inc Diabetesrelaterede biomarkører og fremgangsmåder til anvendelse deraf
EP2145902A3 (en) 2007-04-19 2010-09-29 Peter Hornbeck Tyrosine phosphorylation sites and antibodies specific for them
US7977462B2 (en) 2007-04-19 2011-07-12 Cell Signaling Technology, Inc. Tyrosine phosphorylation sites
EP1983003A3 (en) 2007-04-19 2009-03-11 Peter Hornbeck Tyrosine phosphorylation sites and antibodies specific for them
US20100143336A1 (en) 2007-04-26 2010-06-10 Opsona Therapeutics Limited Toll-like receptor binding epitope and compositions for binding thereto
US20090004677A1 (en) * 2007-04-27 2009-01-01 The Board Of Trustees Of The University Of Illinois Quantitative determination of bcl10
US20090053831A1 (en) 2007-05-01 2009-02-26 Cell Signaling Technology, Inc. Tyrosine phosphorylation sites
US8759258B2 (en) * 2007-05-01 2014-06-24 Hill's Pet Nutrition, Inc. Methods and compositions for diagnosing osteoarthritis in a feline
GB0709092D0 (en) * 2007-05-11 2007-06-20 Borrebaeck Carl Diagnosis and method of disease
WO2008141318A1 (en) * 2007-05-14 2008-11-20 Dr. Susan Love Research Foundation Device for determining risk of developing breast cancer and method thereof
MX2009012722A (es) 2007-05-25 2009-12-11 Decode Genetics Ehf Variantes geneticas sobre chr 5p12 y 10q26 como marcadores para el uso en la evaluacion del riesgo, diagnostico, pronostico y tratamiento del cancer de mama.
US9163091B2 (en) * 2007-05-30 2015-10-20 Lpath, Inc. Compositions and methods for binding lysophosphatidic acid
DK2164992T3 (en) 2007-05-30 2016-08-15 Lpath Inc COMPOSITIONS AND METHODS FOR BONDING OF LYTHOPHOSPHATIC ACID
CN101971033A (zh) * 2007-06-04 2011-02-09 戴诺普雷克斯公司 用于结直肠癌的生物标志物组合
CA2687896A1 (en) 2007-06-05 2008-12-18 Yale University Antibody directed against the d4 ig-like domain of the kit receptor
PL2171090T3 (pl) 2007-06-08 2013-09-30 Genentech Inc Markery ekspresji genów odporności guza na leczenie hamujące HER2
WO2009009127A2 (en) * 2007-07-12 2009-01-15 U.S. Genomics, Inc. Method and system for transferring and/or concentrating a sample
EP2514762B1 (en) 2007-07-13 2015-04-08 The Johns Hopkins University B7-DC variants
CA2694121C (en) * 2007-07-25 2016-06-07 Alexion Pharmaceuticals, Inc. Methods and compositions for treating autoimmune disease
CA2693237C (en) 2007-08-03 2016-11-01 Opsona Therapeutics Limited Anti-toll-like receptor 2 antibodies for use in the treatment of cardiac inflammatory conditions
WO2009022236A2 (en) 2007-08-16 2009-02-19 Tripep Ab Immunogen platform
UA104715C2 (en) 2007-08-29 2014-03-11 Санофи-Авентис Isolated anti-cxcr5 antibody
ES2719728T3 (es) 2007-09-04 2019-07-12 Compugen Ltd Polipéptidos y polinucleótidos, y usos de los mismos como una diana farmacológica para producir fármacos y agentes biológicos
US20090111131A1 (en) * 2007-09-13 2009-04-30 Seth Fishman Method of detecting protein losing enteropathy in animals
CL2008002775A1 (es) 2007-09-17 2008-11-07 Amgen Inc Uso de un agente de unión a esclerostina para inhibir la resorción ósea.
EP2203749B1 (en) 2007-10-05 2012-08-29 Affymetrix, Inc. Highly multiplexed particle-based assays
WO2009047809A2 (en) * 2007-10-12 2009-04-16 Decode Genetics Ehf Sequence variants for inferring human pigmentation patterns
EP2050764A1 (en) 2007-10-15 2009-04-22 sanofi-aventis Novel polyvalent bispecific antibody format and uses thereof
US9096855B2 (en) 2007-10-18 2015-08-04 Cell Signaling Technology, Inc. Translocation and mutant ROS kinase in human non-small cell lung carcinoma
WO2009055538A1 (en) 2007-10-23 2009-04-30 The Cleveland Clinic Foundation Oxidant resistant apolipoprotein a-1 and mimetic peptides
US8361465B2 (en) * 2007-10-26 2013-01-29 Lpath, Inc. Use of anti-sphingosine-1-phosphate antibodies in combination with chemotherapeutic agents
CA2705007A1 (en) 2007-11-07 2009-05-14 Genentech, Inc. Compositions and methods for treatment of microbial disorders
BRPI0819262A2 (pt) 2007-11-08 2017-05-02 Neogenix Oncology Inc anticorpos monoclonais recombinantes e antìgenos correspondentes para cânceres de cólon e pancreático
JP2011503587A (ja) * 2007-11-15 2011-01-27 バイオポルト ディアグノスティックス エイ／エス 独特の分子形態を有するタンパク質バイオマーカーの診断における使用
JP5580205B2 (ja) 2007-11-19 2014-08-27 セレラ コーポレーション 肺癌マーカーとその使用
EP2062920A3 (en) 2007-11-21 2009-06-17 Peter Hornbeck Protein phosphorylation by basophilic serine/threonine kinases in insulin signalling pathways
US8912149B1 (en) 2007-11-28 2014-12-16 California Institute Of Technology Glycosaminoglycan mimetics
CN101970689A (zh) 2007-11-29 2011-02-09 健泰科生物技术公司 炎性肠病的基因表达标志物
US8697360B2 (en) 2007-11-30 2014-04-15 Decode Genetics Ehf. Genetic variants on CHR 11Q and 6Q as markers for prostate and colorectal cancer predisposition
WO2010055366A2 (en) 2007-12-07 2010-05-20 Zymogenetics, Inc. Anti-human il-21 monoclonal antibodies
CN104131030A (zh) * 2007-12-13 2014-11-05 菲利普莫里斯生产公司 就减少的镉转运进行修饰的转基因植物、衍生产物和相关方法
JP2011506483A (ja) * 2007-12-14 2011-03-03 アムジエン・インコーポレーテツド 抗スクレロスチン抗体を用いた骨折の治療方法
US9006191B2 (en) 2007-12-27 2015-04-14 Protiva Biotherapeutics, Inc. Silencing of polo-like kinase expression using interfering RNA
DE202008000834U1 (de) 2008-01-21 2008-05-29 Chin, Li-Te Zusammensetzung und Reagenz für CTLA-4 und Verwendungen derselben
ES2500066T3 (es) 2008-01-25 2014-09-30 Amgen, Inc Anticuerpos frente a ferroportina y métodos de uso
CA2713667A1 (en) * 2008-01-31 2009-08-06 Compugen Ltd. Cd55 isoform and uses therof in cancer detection, monitoring and therapy
CA2618163A1 (en) 2008-02-07 2009-08-07 K. W. Michael Siu Head and neck cancer biomarkers
EP2247755B1 (en) * 2008-02-14 2015-01-28 Decode Genetics EHF Susceptibility variants for lung cancer
CN103884840A (zh) * 2008-02-21 2014-06-25 艾瑞斯国际有限公司 早期确定前列腺癌治疗后复发的方法
US20090220991A1 (en) * 2008-02-29 2009-09-03 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in leukemia signaling pathways
WO2009111315A2 (en) * 2008-02-29 2009-09-11 Mayo Foundation For Medical Education And Research Methods for reducing granulomatous inflammation
US20110136166A1 (en) 2008-03-14 2011-06-09 Eastern Virginia Medical School Imaging Mass Spectrometry for Improved Prostrate Cancer Diagnostics
US8993231B2 (en) * 2008-03-18 2015-03-31 Marshall University Research Corporation Methods for stem cell production and therapy
US8808985B2 (en) 2008-04-01 2014-08-19 Decode Genetics Ehf. Susceptibility variants for peripheral arterial disease and abdominal aortic aneurysm
WO2009123894A2 (en) 2008-04-02 2009-10-08 Macrogenics, Inc. Her2/neu-specific antibodies and methods of using same
MX2010010387A (es) 2008-04-02 2010-10-15 Macrogenics Inc Anticuerpos especificos para el complejo de bcr y metodos para el uso de los mismos.
KR101924831B1 (ko) 2008-04-09 2018-12-05 제넨테크, 인크. 면역 관련 질병의 치료를 위한 신규한 조성물 및 방법
AU2009234389B2 (en) 2008-04-10 2014-08-21 Cell Signaling Technology, Inc. Compositions and methods for detecting EGFR mutations in cancer
WO2009129319A2 (en) 2008-04-15 2009-10-22 Protiva Biotherapeutics, Inc. Silencing of csn5 gene expression using interfering rna
US8058069B2 (en) 2008-04-15 2011-11-15 Protiva Biotherapeutics, Inc. Lipid formulations for nucleic acid delivery
WO2009130588A2 (en) * 2008-04-22 2009-10-29 Tripep Ab Immunogen platform
EP3670538A1 (en) 2008-04-25 2020-06-24 Dyax Corp. Antibodies against fcrn and use thereof
CR20170001A (es) 2008-04-28 2017-08-10 Genentech Inc Anticuerpos anti factor d humanizados
MX2010011717A (es) 2008-05-01 2010-11-30 Amgen Inc Anticuerpos anti-hepcidina y metodos de uso.
EP3284828A1 (en) 2008-05-07 2018-02-21 Eutropics Pharmaceuticals, Inc. Antibodies specific to heterodimers of bcl-2 family and uses thereof
EP2116261A1 (en) 2008-05-07 2009-11-11 Institut Pasteur Sub-region of a plasmodium protein with improved vaccine potential and medical uses thereof
JP2010043063A (ja) 2008-05-09 2010-02-25 Agency For Science Technology & Research 川崎病の診断及び治療
EP2304439A4 (en) 2008-05-29 2012-07-04 Nuclea Biotechnologies Llc ANTI-phospho-AKT ANTIBODY
US20110081347A1 (en) 2008-06-04 2011-04-07 Macrogenics, Inc. Antibodies with Altered Binding to FcRn and Methods of Using Same
JOP20190083A1 (ar) 2008-06-04 2017-06-16 Amgen Inc بولي ببتيدات اندماجية طافرة لـfgf21 واستخداماتها
US20110123542A1 (en) * 2008-06-24 2011-05-26 Hadasit Medical Research Services And Development Ltd. Ccl20-specific antibodies for cancer therapy
HRP20241467T1 (hr) 2008-06-25 2025-01-03 Novartis Ag Stabilna i topljiva protutijela koja inhibiraju vegf
US8673310B2 (en) 2008-06-25 2014-03-18 ESBA Tech, an Alcon Biomedical Research Unit LLC Stable and soluble antibodies inhibiting TNFα
CN102132160A (zh) * 2008-06-26 2011-07-20 达纳-法伯癌症研究院有限公司 与转移有关的信号和决定子以及它们的使用方法及用途
AU2009262199B2 (en) 2008-06-27 2012-08-09 Amgen Inc. Ang-2 inhibition to treat multiple sclerosis
CN102137938B (zh) 2008-07-04 2015-01-21 解码遗传学私营有限责任公司 预测精神分裂症的风险的拷贝数变异
JP2011527565A (ja) 2008-07-07 2011-11-04 ディコーデ ジェネテクス イーエイチエフ 乳癌のリスクアセスメントのための遺伝的変異
WO2010006048A2 (en) 2008-07-08 2010-01-14 Source Precision Medicine, Inc. Gene expression profiling for predicting the survivability of prostate cancer subjects
ES2442024T3 (es) 2008-07-15 2014-02-07 Academia Sinica Matrices de glucano sobre portaobjetos de vidrio revestidos con aluminio de tipo PTFE y métodos relacionados
WO2010009438A1 (en) 2008-07-17 2010-01-21 Andreas Pfuetzner Biomarkers for insulin resistance and beta-cell dysfunction
AU2009272369B2 (en) 2008-07-17 2016-04-14 Ikfe Institut Fur Klinische Forschung Und Entwicklung Gmbh Biomarkers for cardiodiabetes
US20100021472A1 (en) * 2008-07-25 2010-01-28 Geetha Srikrishna Methods for diagnosing and treating cancer
US8795981B2 (en) * 2008-08-08 2014-08-05 Molecular Devices, Llc Cell detection
US20110143375A1 (en) 2008-08-11 2011-06-16 Banyan Blomakers, Inc. Biomarker detection process and assay of neurological condition
JP2011530306A (ja) * 2008-08-12 2011-12-22 ディコーデ ジェネテクス イーエイチエフ 甲状腺癌のリスクアセスメントに有用な遺伝的変異
WO2010018601A2 (en) * 2008-08-15 2010-02-18 Decode Genetics Ehf Genetic variants predictive of cancer risk
MX2011001900A (es) 2008-08-18 2011-08-17 Seoul Nat Univ Ind Foundation Metodo para controlar metastasis de cancer o migracion de celulas de cancer modulando el nivel celular de lisil-tarn sintetasa.
DK2350129T3 (en) 2008-08-25 2015-08-31 Amplimmune Inc PREPARATIONS WITH PD-1 ANTAGONISTS AND PROCEDURES FOR USE THEREOF
CA2735006A1 (en) 2008-08-25 2010-03-11 Amplimmune, Inc. Pd-1 antagonists and methods of use thereof
DK2324060T3 (en) 2008-09-07 2015-10-26 Glyconex Inc ANTI-EXTENDED TYPE I glycosphingolipid ANTIBODY, DERIVATIVES AND USE
CA2734694A1 (en) 2008-09-10 2010-03-18 Genentech, Inc. Methods for inhibiting ocular angiogenesis
WO2010030167A2 (en) 2008-09-12 2010-03-18 Cancer Research Initiative Foundation Method of detection and diagnosis of oral and nasopharyngeal cancers
US8417011B2 (en) 2008-09-18 2013-04-09 Molecular Devices (New Milton) Ltd. Colony detection
US20110200525A1 (en) * 2008-10-09 2011-08-18 Patz Jr Edward F Vhh antibody fragments for use in the detection and treatment of cancer
EP2358749B1 (en) 2008-10-10 2018-07-18 Amgen, Inc Fgf21 mutants and uses thereof
US20110262446A1 (en) 2008-10-14 2011-10-27 Dyax Corp. Use of igf-ii/igf-iie binding proteins for the treatment and prevention of systemic sclerosis associated pulmonary fibrosis
CN102257000B (zh) * 2008-10-21 2014-10-08 国际疫苗研究所 新型志贺氏菌蛋白抗原及方法
US8871202B2 (en) 2008-10-24 2014-10-28 Lpath, Inc. Prevention and treatment of pain using antibodies to sphingosine-1-phosphate
CN107050442B (zh) * 2008-11-05 2022-09-13 惠氏有限责任公司 用于预防β-溶血链球菌(BHS)疾病的多组分免疫原性组合物
RS64039B1 (sr) 2008-11-10 2023-04-28 Alexion Pharma Inc Metode i kompozicije za lečenje poremećaja povezanih sa komplementom
AT507604A1 (de) 2008-11-19 2010-06-15 Affiris Forschungs & Entwicklungs Gmbh Behandlung von atherosklerose
ATE523603T1 (de) 2008-11-21 2011-09-15 Chimera Biotec Gmbh Konjugatkomplexe zum analytnachweis
JP2012509941A (ja) 2008-11-26 2012-04-26 ファイブ・プライム・セラピューティクス，インコーポレイテッド Ｓｅｒｐｉｎｅ２によるコラーゲンおよび平滑筋アクチンの発現を調節するための組成物および方法
WO2010061393A1 (en) 2008-11-30 2010-06-03 Compugen Ltd. He4 variant nucleotide and amino acid sequences, and methods of use thereof
MX2011005915A (es) 2008-12-03 2011-08-17 Proyecto Biomedicina Cima Sl Uso de modulinas solubles en fenol para el desarrollo de vacunas.
WO2010064250A1 (en) 2008-12-04 2010-06-10 Yeda Research And Development Co. Ltd. Compositions and methods for diagnosing and treating cancer and neurodegenerative diseases related to beclin-1
WO2010065867A1 (en) 2008-12-04 2010-06-10 Pioneer Hi-Bred International, Inc. Methods and compositions for enhanced yield by targeted expression of knotted1
US20100256196A1 (en) 2008-12-04 2010-10-07 Ikfe Biomarkers for Atherosclerosis
EP2373690B1 (en) 2008-12-08 2015-02-11 Compugen Ltd. Antibodies specific for tmem154
WO2010067207A1 (en) 2008-12-11 2010-06-17 Ikfe Gmbh Biomarkers for insulin sensitizer drug response
EP2382467A1 (en) 2008-12-30 2011-11-02 IKFE GmbH Biomarkers for adipose tissue activity
US20100210541A1 (en) 2009-01-07 2010-08-19 Andreas Pfuetzner Biomarkers for Appetite Regulation
BRPI1007483B1 (pt) 2009-01-28 2021-11-30 Bio Preventive Medicine Corporation Método de diagnóstico de nefropatia in vitro, método in vitro para o monitoramento de progresso de nefropatia, método in vitro para o monitoramento da eficácia de um tratamento de nefropatia, método in vitro de avaliação de toxicidade renal de um agente e kit para diagnóstico de nefropatia
EP2392351A4 (en) 2009-01-28 2012-12-12 Univ Tokai Educational System INHIBITOR OF HIV REPLICATION AND USE
EP2396661A4 (en) 2009-02-11 2013-10-30 Caris Mpi Inc MOLECULAR PROFILING OF TUMORS
EP3266795A1 (en) 2009-02-12 2018-01-10 Cell Signaling Technology, Inc. Method for detecting a fig-ros fusion polynucleotide
EP2396035A4 (en) 2009-02-12 2012-09-12 Human Genome Sciences Inc USE OF ANTAGONISTS OF PROTEIN STIMULATING LYMPHOCYTES B TO PROMOTE GRAFT TOLERANCE
CA2982157A1 (en) 2009-02-16 2010-08-19 Cerenis Therapeutics Holding Sa Apolipoprotein a-i mimics
US20100248265A1 (en) * 2009-02-27 2010-09-30 The Salk Institute For Biological Studies Compositions and methods for diagnosis and treatment of cancer
US8772238B2 (en) 2009-03-18 2014-07-08 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Use of ixolaris, a tissue factor inhibitor, for the treatment of cancer
EP2233496A1 (en) 2009-03-26 2010-09-29 Ruhr-Universität Bochum Fluorescent proteins
BRPI1014121A2 (pt) 2009-03-27 2016-11-08 Gojo Ind Inc composições e métodos para investigação e uso de compostos que antagonizam as interações esporo-superfície
WO2010112033A2 (en) 2009-03-31 2010-10-07 Østjysk Innovation A/S Method for estimating the risk of having or developing multiple sclerosis using sequence polymorphisms in a specific region of chromosome x
CA2757384A1 (en) 2009-04-03 2010-10-07 Decode Genetics Ehf. Determination of genetic risk of atrial fibrillation and stroke associated with rs7193343 and correlated markers
NZ596037A (en) 2009-05-05 2013-10-25 Amgen Inc Fgf21 mutants and uses thereof
WO2010129600A2 (en) 2009-05-05 2010-11-11 Amgen Inc. Fgf21 mutants and uses thereof
US20110301093A1 (en) 2009-05-06 2011-12-08 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Compositions and methods for diagnosing and treating cancer and neurodegenerative diseases related to beclin-1
AU2010245598A1 (en) * 2009-05-08 2011-11-17 Decode Genetics Ehf Genetic variants contributing to risk of prostate cancer
WO2010148142A1 (en) 2009-06-17 2010-12-23 Amgen Inc. Chimeric fgf19 polypeptides and uses thereof
CZ2011827A3 (cs) 2009-06-25 2012-09-26 Savient Pharmaceuticals, Inc. Zpusoby a sady pro predpovídání rizika reakce na infuzi a ztráty odezvy zpusobené protilátkami, monitorováním kyseliny mocové v séru behem lécby pegylovanou urikázou
IL199618A0 (en) 2009-06-29 2010-04-29 Two To Biotech Ltd Novel antibodies and their use in diagnostic methods
WO2011000805A1 (en) 2009-06-29 2011-01-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Biomarkers of oocyte competency and method of use
IL292615B2 (en) 2009-07-01 2023-11-01 Protiva Biotherapeutics Inc Nucleic acid-lipid particles, preparations containing them and their uses
IE20090514A1 (en) 2009-07-06 2011-02-16 Opsona Therapeutics Ltd Humanised antibodies and uses therof
US8796182B2 (en) 2009-07-10 2014-08-05 Decode Genetics Ehf. Genetic markers associated with risk of diabetes mellitus
WO2011004379A1 (en) 2009-07-10 2011-01-13 Tel Hashomer Medical Research Infrastructure And Services Ltd. Compositions and methods for treating cancer
WO2011011447A1 (en) 2009-07-20 2011-01-27 Protiva Biotherapeutics, Inc. Compositions and methods for silencing ebola virus gene expression
SG177699A1 (en) 2009-07-20 2012-02-28 Genentech Inc Gene expression markers for crohn's disease
US9493834B2 (en) 2009-07-29 2016-11-15 Pharnext Method for detecting a panel of biomarkers
IL200202A0 (en) 2009-08-02 2010-05-31 Orly Devary Novel proteins
KR102033276B1 (ko) 2009-08-03 2019-10-16 유니버시티 오브 마이애미 T 조절 세포의 생체 내 확장 방법
EP2467398B1 (en) 2009-08-20 2019-10-09 Poseida Therapeutics, Inc. Trpc4 inhibitors and uses thereof
CA2808611A1 (en) * 2009-08-28 2011-03-03 Inova Diagnostics, Inc. Detecting circulating cartilage oligomeric matrix protein in liver cirrhosis
CN102666581A (zh) 2009-08-31 2012-09-12 艾普利穆恩公司 用于抑制移植物排斥的方法和组合物
ES2538007T3 (es) 2009-09-16 2015-06-16 Vaxart, Inc. Estrategia de inmunización para prevenir una infección por H1N1
WO2011038160A2 (en) 2009-09-23 2011-03-31 Protiva Biotherapeutics, Inc. Compositions and methods for silencing genes expressed in cancer
US8926976B2 (en) 2009-09-25 2015-01-06 Xoma Technology Ltd. Modulators
EP2480888B1 (en) 2009-09-25 2016-11-30 XOMA Technology Ltd. Screening methods
EP2482798A1 (en) * 2009-10-01 2012-08-08 Alcon Research, Ltd. Olopatadine compositions and uses thereof
US9377458B2 (en) 2009-10-11 2016-06-28 Biogen Ma Inc. Anti-VLA-4 related assays
AU2010306593B2 (en) 2009-10-15 2015-09-10 Crescendo Bioscience, Inc. Biomarkers and methods for measuring and monitoring inflammatory disease activity
WO2011048598A1 (en) 2009-10-22 2011-04-28 Yeda Research And Development Co. Ltd. Compositions and methods for treating aspergillosis
PH12012500665B1 (en) 2009-10-23 2019-10-30 Amgen British Columbia Anti-gcc antibody molecules and related compositions and methods
DK2494356T3 (en) * 2009-10-26 2017-05-15 Genentech Inc ASSAYS FOR THE DETECTION OF ANTIBODIES SPECIFIC TO THERAPEUTIC ANTI-IGE ANTIBODIES AND THEIR USE OF ANAPHYLAXY
CA2779223A1 (en) 2009-10-27 2011-05-12 Caris Mpi, Inc. Molecular profiling for personalized medicine
WO2011059721A1 (en) 2009-10-29 2011-05-19 Tethys Bioscience, Inc. Protein and lipid biomarkers providing consistent improvement to the prediction of type 2 diabetes
JP2013509587A (ja) 2009-10-29 2013-03-14 テシス バイオサイエンス， インコーポレイテッド 糖尿病のリスクを決定する方法
WO2011058367A2 (en) 2009-11-13 2011-05-19 Astrazeneca Ab Diagnostic test for predicting responsiveness to treatment with poly(adp-ribose) polymerase (parp) inhibitor
US8592151B2 (en) * 2009-11-17 2013-11-26 Musc Foundation For Research Development Assessing left ventricular remodeling via temporal detection and measurement of microRNA in body fluids
WO2011067711A2 (en) 2009-12-01 2011-06-09 Compugen Ltd Novel heparanase splice variant
US11377485B2 (en) 2009-12-02 2022-07-05 Academia Sinica Methods for modifying human antibodies by glycan engineering
US10087236B2 (en) 2009-12-02 2018-10-02 Academia Sinica Methods for modifying human antibodies by glycan engineering
CA2782814A1 (en) * 2009-12-02 2011-06-09 Amgen Inc. Binding proteins that bind to human fgfr1c, human .beta.-klotho and both human fgfr1c and human .beta.-klotho
KR101974044B1 (ko) 2009-12-07 2019-04-30 피어이스 파마슈티컬즈 게엠베하 주어진 표적에 대한 친화성을 갖는 인간의 리포칼린 2의 뮤테인
UA109888C2 (uk) 2009-12-07 2015-10-26 ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
CN102812348B (zh) 2009-12-22 2016-02-03 新加坡科技研究局 基于sers的分析物检测
DK2516468T3 (en) 2009-12-23 2016-05-23 Synimmune Gmbh ANTI-FLT3 ANTIBODIES AND METHODS FOR USING THESE
JP6037841B2 (ja) 2010-01-06 2016-12-07 ダイアックス コーポレーション 血漿カリクレイン結合タンパク質
IN2012DN06139A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2010-01-11 2015-09-18 Biogen Idec Inc
US11287423B2 (en) 2010-01-11 2022-03-29 Biogen Ma Inc. Assay for JC virus antibodies
CA2786692A1 (en) 2010-01-11 2011-07-14 Alexion Pharmaceuticals, Inc. Biomarkers of immunomodulatory effects in humans treated with anti-cd200 antibodies
WO2011089211A1 (en) 2010-01-22 2011-07-28 Synimmune Gmbh Anti-cd133 antibodies and methods of using the same
WO2012141674A2 (en) 2010-01-26 2012-10-18 Banyan Biomarkers, Inc. Compositions and methods relating to argininosuccinate synthetase
US8697078B2 (en) 2010-01-27 2014-04-15 Yeda Research And Development Co. Ltd. Antibodies that inhibit metalloproteins
CN102781517B (zh) 2010-02-01 2015-11-25 小利兰·斯坦福大学托管委员会 诊断和治疗非胰岛素依赖性糖尿病的方法
TWI518325B (zh) 2010-02-04 2016-01-21 自治醫科大學 對ａｌｋ抑制劑具有先抗性或後抗性癌症的識別、判斷和治療
JP4686639B1 (ja) * 2010-02-25 2011-05-25 田中貴金属工業株式会社 生豚肉検出法およびその検出キット
WO2011106738A2 (en) 2010-02-25 2011-09-01 Fred Hutchinson Cancer Research Center Use of tcr clonotypes as biomarkers for disease
WO2011106723A2 (en) * 2010-02-26 2011-09-01 Lpath, Inc. Anti-paf antibodies
US20130058915A1 (en) 2010-03-02 2013-03-07 Children's Medica Center Corporation Methods and compositions for treatment of angelman syndrome and autism spectrum disorders
US20110237000A1 (en) * 2010-03-11 2011-09-29 Agency For Science, Technology And Research Method for detecting an analyte molecule
US10745467B2 (en) 2010-03-26 2020-08-18 The Trustees Of Dartmouth College VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
US20150231215A1 (en) 2012-06-22 2015-08-20 Randolph J. Noelle VISTA Antagonist and Methods of Use
MX374075B (es) 2010-03-26 2025-03-05 Dartmouth College Proteina mediadora de celula t regulatoria vista, agentes de enlace de vista y uso de los mismos.
EP2556169B1 (en) 2010-04-07 2018-02-14 Imperial Innovations Limited Methods for categorising cancer such as breast cancer
US10338069B2 (en) 2010-04-12 2019-07-02 Academia Sinica Glycan arrays for high throughput screening of viruses
MX2012011986A (es) 2010-04-15 2013-03-05 Amgen Inc RECEPTOR FGF HUMANO Y PROTEINAS ENLAZADAS A ß-KLOTHO.
US8785385B2 (en) 2010-04-19 2014-07-22 Research Development Foundation RTEF-1 variants and uses thereof
EP2561363B1 (en) 2010-04-21 2021-07-14 Memed Diagnostics, Ltd. Signatures and determinants for distinguishing between a bacterial and viral infection and methods of use thereof
CN107641151B (zh) 2010-05-14 2021-10-01 百深公司 Ospa嵌合体及其在疫苗中的用途
SMT202000095T1 (it) 2010-05-14 2020-03-13 Amgen Inc Formulazioni di anticorpi anti-sclerostina ad alta concentrazione
US20110287458A1 (en) 2010-05-18 2011-11-24 The Texas A&M University System Method and composition for the diagnosis and monitoring of inflammatory diseases
WO2011146725A1 (en) 2010-05-19 2011-11-24 Bayer Healthcare Llc Biomarkers for a multikinase inhibitor
WO2011145085A2 (en) 2010-05-21 2011-11-24 Procognia (Israel) Ltd Novel antibodies and methods of use for the treatment and diagnosis of cancer
WO2011161545A2 (en) 2010-06-04 2011-12-29 The Netherlands Cancer Institute Non-hydrolyzable protein conjugates, methods and compositions related thereto
US8383580B2 (en) 2010-06-10 2013-02-26 The Regents Of The University Of Michigan Methods of administering lipocalins to treat metabolic disorders and cardiovascular diseases
GB201009798D0 (en) 2010-06-11 2010-07-21 Immunovia Ab Method,array and use thereof
US20130189268A1 (en) 2010-06-22 2013-07-25 Precision Biologics, Inc. Colon and pancreas cancer specific antigens and antibodies
US9695410B2 (en) 2010-07-15 2017-07-04 Technion Research & Development Foundation Limited Isolated high affinity entities with T-cell receptor like specificity towards native complexes of MHC class II and glutamic acid decarboxylase (GAD) autoantigenic peptides
CA2805478A1 (en) 2010-07-15 2012-01-19 Technion Research & Development Foundation Ltd. Isolated high affinity entities with t-cell receptor like specificity towards native complexes of mhc class ii and diabetes-associated autoantigenic peptides
EP2601212A1 (en) 2010-08-04 2013-06-12 Cizzle Biotechnology Limited Methods and compounds for the diagnosis and treatment of
WO2012019132A2 (en) 2010-08-06 2012-02-09 Cell Signaling Technology, Inc. Anaplastic lymphoma kinase in kidney cancer
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
CA2807209C (en) 2010-08-16 2019-09-17 Mount Sinai Hospital Markers of the male urogenital tract
WO2012024535A2 (en) 2010-08-18 2012-02-23 Fred Hutchinson Cancer Research Center Methods for determining the presence or risk of developing facioscapulohumeral dystrophy (fshd)
US10088490B2 (en) 2010-08-20 2018-10-02 Siemens Healthcare Diagnostics Inc. Assay for analytes using multiple receptors
HRP20240965T1 (hr) 2010-08-23 2024-10-25 Wyeth Llc Stabilne formulacije antigena rlp2086 iz bakterije neisseria meningitidis
WO2012030738A2 (en) 2010-08-30 2012-03-08 Beckman Coulter, Inc. Complex phosphoprotein activation profiles
US9982304B2 (en) 2010-09-03 2018-05-29 The Johns Hopkins University ARID1A and PPP2R1A mutations in cancer
GB201014837D0 (en) 2010-09-07 2010-10-20 Immunovia Ab Biomarker signatures and uses thereof
EP3549601B1 (en) 2010-09-10 2021-02-24 Wyeth LLC Non-lipidated variants of neisseria meningitidis orf2086 antigens
EP2616100B1 (en) 2010-09-17 2016-08-31 Compugen Ltd. Compositions and methods for treatment of drug resistant multiple myeloma
WO2012038744A2 (en) 2010-09-22 2012-03-29 Genome Research Limited Detecting mutations
US9068014B2 (en) 2010-09-23 2015-06-30 Precision Biologics, Inc. Colon and pancreas cancer peptidomimetics
US8497138B2 (en) 2010-09-30 2013-07-30 Genetix Limited Method for cell selection
US9006458B2 (en) 2010-10-12 2015-04-14 Agency For Science, Technology And Research Surface Enhanced Raman Spectroscopy (SERS) compounds and methods of their preparation
EP2444084A1 (en) 2010-10-21 2012-04-25 Centro Nacional de Investigaciones Oncológicas (CNIO) Use of PI3K inibitors for the treatment of obesity
EP2630499A2 (en) 2010-10-21 2013-08-28 Vertex Pharmaceuticals Incorporated Biomarkers for hcv infected patients
UY33679A (es) 2010-10-22 2012-03-30 Esbatech Anticuerpos estables y solubles
GB201018014D0 (en) 2010-10-26 2010-12-08 Senzagen Ab Analytical methods and arrays for use in the same
CN103370337B (zh) 2010-10-28 2015-12-09 耶达研究及发展有限公司 用于产生针对金属酶的抗体的方法
US8361720B2 (en) 2010-11-15 2013-01-29 Exact Sciences Corporation Real time cleavage assay
WO2012068355A2 (en) 2010-11-18 2012-05-24 Tufts Medical Center, Inc. Treating aortic aneurysm by modulating toll-like receptors
AU2011332817A1 (en) 2010-11-23 2013-06-13 Alder Biopharmaceuticals, Inc. Anti-IL-6 antibodies for the treatment of anemia
DK2643017T3 (da) 2010-11-23 2019-08-26 Pantheryx Inc Sammensætninger og fremgangsmåder ved behandling i udifferentierede eller blandede kliniske anvendelser med bredt spektrum
EP2477032A1 (en) 2011-01-18 2012-07-18 Baxter International Inc Measurement of anti-amyloid antibodies in human blood
JP2014507649A (ja) 2011-01-18 2014-03-27 バクスター・インターナショナル・インコーポレイテッド ヒト血液中の抗βアミロイド抗体の測定
AR085141A1 (es) 2011-02-03 2013-09-11 Alexion Pharma Inc Un metodo para prolongar la supervivencia de un aloinjerto renal, uso de un anticuerpo anti-cd200 para prolongar la supervivencia de aloinjertos
FR2971256B1 (fr) 2011-02-09 2024-09-27 Bio Rad Pasteur Combinaison de biomarqueurs pour la detection et l'evaluation d'une fibrose hepatique
FR2971257B1 (fr) 2011-02-09 2020-12-04 Bio Rad Pasteur Combinaison de biomarqueurs pour le pronostic d'une reponse ou non-reponse a un traitement anti-vhc
FR2971258B1 (fr) 2011-02-09 2020-12-04 Bio Rad Pasteur Combinaison de biomarqueurs pour le pronostic d'une reponse ou non-reponse a un traitement anti-vhc
JP2014510721A (ja) 2011-02-15 2014-05-01 イミューン デザイン コーポレイション ベクターワクチンによる免疫原特異的免疫応答を強化するための方法
CN102675460B (zh) 2011-02-28 2015-08-19 珠海市丽珠单抗生物技术有限公司 抗肿瘤坏死因子α的人源化抗体
US8658171B2 (en) 2011-02-28 2014-02-25 Livzon Mabpharm Inc. Humanized anti-TNFα antibodies
JP2014509588A (ja) 2011-03-01 2014-04-21 アムジエン・インコーポレーテツド 二特異性結合剤
GB201103726D0 (en) 2011-03-04 2011-04-20 Immunovia Ab Method, array and use thereof
US9296818B2 (en) 2011-03-14 2016-03-29 Marene Inga-Britt Landstrom Cleavage inhibitors of transforming growth factor beta type I receptor and uses thereof in cancer therapy
TWI700093B (zh) 2011-03-16 2020-08-01 法商賽諾菲公司 雙重ｖ區類抗體蛋白質之用途
CN103517920B (zh) 2011-03-25 2018-04-17 安进公司 抗硬化蛋白(sclerostin)抗体晶体及其制剂
WO2012139058A1 (en) 2011-04-08 2012-10-11 Biogen Idec Ma Inc. BIOMARKERS PREDICTIVE OF THERAPEUTIC RESPONSIVENESS TO IFNβ AND USES THEREOF
SG194083A1 (en) 2011-04-08 2013-11-29 Immune Design Corp Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses
WO2012142164A1 (en) 2011-04-12 2012-10-18 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Human monoclonal antibodies that bind insulin-like growth factor (igf) i and ii
CN103596974B (zh) 2011-04-15 2016-08-31 卡姆普根有限公司 多肽和多核苷酸及其用于治疗免疫相关失调和癌症的用途
CN103619880A (zh) 2011-04-29 2014-03-05 百时美施贵宝公司 Ip-10抗体剂量递增方法
PL3498732T3 (pl) 2011-05-06 2022-02-28 Zoetis Services Llc Przeciwciała przeciw czynnikowi wzrostu nerwów oraz sposoby ich otrzymywania i zastosowania
GB2504887B (en) 2011-05-06 2016-02-03 Nvip Pty Ltd Anti-Nerve growth factor antibodies and methods of preparing and using the same
GB201114858D0 (en) 2011-08-29 2011-10-12 Nvip Pty Ltd Anti-nerve growth factor antibodies and methods of using the same
CA2835094C (en) 2011-05-06 2020-12-22 David Gearing Anti-nerve growth factor antibodies and methods of preparing and using the same
BR112013028652A8 (pt) 2011-05-06 2017-12-26 Nvip Pty Ltd Anticorpos anti-fator de crescimento neuronal e métodos para preparação e utilização dos mesmos
WO2012156825A1 (en) 2011-05-17 2012-11-22 Genoscience Pharma Peptide-based hiv pre-integration complex inhibitors
ES2765874T3 (es) 2011-05-25 2020-06-11 Innate Pharma Sa Anticuerpos anti-KIR para el tratamiento de trastornos inflamatorios
EP2715352B1 (en) 2011-05-31 2019-04-24 Biogen MA Inc. Method of assessing risk of pml
KR102014554B1 (ko) 2011-06-02 2019-08-26 다이액스 코포레이션 Fc 수용체 결합 단백질
KR20140147797A (ko) 2011-06-27 2014-12-30 더 잭슨 래보라토리 암 및 자가면역 질환의 치료 방법 및 조성물
AU2012277376B2 (en) 2011-06-30 2016-11-24 Compugen Ltd. Polypeptides and uses thereof for treatment of autoimmune disorders and infection
WO2013014669A1 (en) 2011-07-24 2013-01-31 Carmel-Haifa University Economic Corp. Lactoferrin fragments and use thereof
AU2011373900B8 (en) 2011-07-27 2015-08-06 Bio-Rad Innovations A2M fragments and applications thereof
BR112014002141A2 (pt) 2011-08-02 2017-02-21 Pfizer crizotinib para uso no tratamento de câncer
EP2739975B1 (en) 2011-08-03 2015-06-17 Quidel Corporation N-acetyl-d-glucosamine for enhanced specificity of strep a immunoassay
US10538584B2 (en) 2011-08-04 2020-01-21 Amgen Inc. Methods for treating bone gap defects
EP3564261B1 (en) 2011-08-23 2024-11-13 Foundation Medicine, Inc. Kif5b-ret fusion molecules and uses thereof
EP2751139A1 (en) 2011-08-30 2014-07-09 NVIP Pty Ltd Caninised tumour necrosis factor antibodies and methods of using the same
KR101425032B1 (ko) 2011-09-22 2014-07-31 재단법인 의약바이오컨버젼스연구단 류신 티알엔에이 합성효소의 신규한 용도
WO2013045863A1 (fr) 2011-09-29 2013-04-04 Institut Pasteur Detection de souches e.coli de serotype o104
EP2581384A1 (en) 2011-10-11 2013-04-17 Institut Pasteur Products useful for the treatment of malignant neoplasms of the human nervous system
TW201321414A (zh) 2011-10-14 2013-06-01 Genentech Inc 抗－ＨｔｒＡ１抗體及其使用方法
WO2013056178A2 (en) 2011-10-14 2013-04-18 Foundation Medicine, Inc. Novel estrogen receptor mutations and uses thereof
CA2848587A1 (en) 2011-10-17 2013-04-25 Westfaelische Wilhelms-Universitaet Muenster Methods of risk assessment of pml and related apparatus
CN106011243A (zh) 2011-11-10 2016-10-12 霍夫曼-拉罗奇有限公司 用于治疗、诊断和监测阿尔茨海默病的方法
WO2013071066A1 (en) 2011-11-11 2013-05-16 The Broad Institute, Inc. Signatures associated with the response to cancer therapy
CN103917870B (zh) 2011-11-16 2016-04-13 贝克顿·迪金森公司 用于检测样品中的分析物的方法和系统
JP6000369B2 (ja) 2011-11-29 2016-09-28 テレフレックス メディカル インコーポレイテッドＴｅｌｅｆｌｅｘ Ｍｅｄｉｃａｌ Ｉｎｃｏｒｐｏｒａｔｅｄ 一体型アレルギー検査方式の器具
US9554736B2 (en) 2011-11-29 2017-01-31 Teleflex Medical Incorporated Device with integrated allergy testing
RU2019103083A (ru) 2011-11-30 2019-03-22 Дженентек, Инк. МУТАЦИИ ErbB3 ПРИ РАКЕ
EP3483288B1 (en) 2011-11-30 2022-03-16 Children's Hospital Medical Center Personalized pain management and anesthesia: preemptive risk identification
LT2790687T (lt) 2011-12-16 2018-12-10 Poseida Therapeutics, Inc. Trpc4 moduliatoriai, skirti panaudoti skausmo gydymui arba prevencijai
US9035039B2 (en) 2011-12-22 2015-05-19 Protiva Biotherapeutics, Inc. Compositions and methods for silencing SMAD4
EP2794626B3 (en) 2011-12-22 2020-08-05 GlycoMimetics, Inc. E-selectin antagonist compounds
EP3712168A3 (en) 2011-12-28 2020-10-14 Amgen Inc. Method of treating alveolar bone loss through the use of anti-sclerostin antibodies
EP2797632A1 (en) 2012-01-01 2014-11-05 QBI Enterprises Ltd. Endo180-targeted particles for selective delivery of therapeutic and diagnostic agents
HUE041900T2 (hu) 2012-01-20 2019-06-28 Genzyme Corp Anti-CXCR3 ellenanyagok
AU2012367247B2 (en) 2012-01-24 2018-04-05 Cd Diagnostics, Inc. System for detecting infection in synovial fluid
SG2014008304A (en) 2012-02-01 2014-06-27 Compugen Ltd C10rf32 antibodies, and uses thereof for treatment of cancer
IN2014MN01780A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2012-02-09 2015-07-03 Memed Diagnostics Ltd
RU2020111326A (ru) 2012-02-24 2020-04-29 Протива Байотерапьютикс Инк. Триалкил катионные липиды и способы их использования
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
KR101784644B1 (ko) 2012-03-09 2017-10-11 화이자 인코포레이티드 수막염균 조성물 및 이의 사용 방법
WO2013142796A2 (en) 2012-03-23 2013-09-26 Bristol-Myers Squibb Company Methods of treatments using ctla4 antibodies
US9592289B2 (en) 2012-03-26 2017-03-14 Sanofi Stable IgG4 based binding agent formulations
RU2014143251A (ru) 2012-03-28 2016-05-20 Дженентек, Инк. Антиидиотипические антитела к hcmv и их применение
EP2647995B8 (en) 2012-04-02 2015-02-18 Roche Diagnostics GmbH Methods and use for assessing chronic obstructive pulmonary disease (COPD) severity
US10130714B2 (en) 2012-04-14 2018-11-20 Academia Sinica Enhanced anti-influenza agents conjugated with anti-inflammatory activity
WO2013158859A1 (en) 2012-04-18 2013-10-24 Cell Signaling Technology, Inc. Egfr and ros1 in cancer
GB201207297D0 (en) 2012-04-26 2012-06-06 Senzagen Ab Analytical methods and arrays for use in the same
US9156915B2 (en) 2012-04-26 2015-10-13 Thomas Jefferson University Anti-GCC antibody molecules
WO2013170054A2 (en) 2012-05-09 2013-11-14 Advanced Animal Diagnostics, Inc. Autofocus method for imaging a biological sample and cartridge for use therein
MX361457B (es) 2012-05-11 2018-12-06 Reset Therapeutics Inc Sulfonamidas que contienen carbazol como moduladoras de criptocromo.
SG11201406729TA (en) 2012-05-31 2014-11-27 Agency Science Tech & Res Surface enhanced raman spectroscopy (sers) marker conjugates and methods of their preparation
US10155987B2 (en) 2012-06-12 2018-12-18 Dana-Farber Cancer Institute, Inc. Methods of predicting resistance to JAK inhibitor therapy
TWI705073B (zh) 2012-06-22 2020-09-21 達特茅斯學院基金會 新穎之vista-ig構築體及vista-ig用於治療自體免疫、過敏及發炎病症之用途
US9890215B2 (en) 2012-06-22 2018-02-13 King's College London Vista modulators for diagnosis and treatment of cancer
EP2869844B2 (en) 2012-07-05 2023-06-21 UCB Pharma S.A. Treatment for bone diseases
DE202012012084U1 (de) 2012-07-09 2013-04-15 Schebo Biotech Ag Testkit (Kombi-Schnelltest) zum synchronen Nachweis von Biomarkern im Stuhl zur Erkennung pathologischer Veränderungen im Gastrointestinaltrakt, insbesondere im Darm
DE102012013888A1 (de) 2012-07-09 2014-05-22 Schebo Biotech Ag Testkit (Kombi-Schnelltest) zum synchronen Nachweis von Biomarkern im Stuhl zur Erkennung pathologischer Veränderungen im Gastrointestinaltrakt, insbesondere im Darm
US9610324B2 (en) 2012-07-11 2017-04-04 Esperion Therapeutics, Inc. Apolipoprotein mixtures
WO2014015217A1 (en) 2012-07-19 2014-01-23 Vertex Pharmaceuticals Incorporated Biomarkers for hcv infected patients
EP2687850A1 (en) 2012-07-19 2014-01-22 Roche Diagniostics GmbH Methods of stratifying for respiratory support therapy
WO2014018375A1 (en) 2012-07-23 2014-01-30 Xenon Pharmaceuticals Inc. Cyp8b1 and uses thereof in therapeutic and diagnostic methods
AU2013293448A1 (en) 2012-07-27 2015-02-05 Baxalta GmbH Compositions comprising chimeric OspA molecules and methods of use thereof
CA3163776A1 (en) 2012-08-03 2014-02-06 Foundation Medicine, Inc. Human papilloma virus as predictor of cancer prognosis
SG11201408340SA (en) 2012-08-14 2015-01-29 Univ Nanyang Tech Angiopoietin-like 4 antibody and a method of its use in cancer treatment
EP2885422B1 (en) 2012-08-15 2018-03-21 The Procter and Gamble Company Systems, models and methods for identifying and evaluating skin-active agents effective for treating an array of skin disorders
JP6302909B2 (ja) 2012-08-18 2018-03-28 アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ シアリダーゼの同定および画像化のための細胞透過性プローブ
US20140056901A1 (en) 2012-08-21 2014-02-27 The Institute For Molecular Medicine Anti-tau antibodies and compositions for and methods of making and using in treatment, diagnosis and monitoring of tauopathies
CA2884704C (en) 2012-09-07 2023-04-04 Randolph J. Noelle Vista modulators for diagnosis and treatment of cancer
JP6502851B2 (ja) 2012-09-10 2019-04-17 ヴェストファーリッシュ ヴィルヘルム−ユニバーシテート ミュンスター 炎症性状態の予防、処置、および診断のための方法および化合物
US10288626B2 (en) 2012-09-14 2019-05-14 University Of Kentucky Research Foundation Secreted tumor-associated cytochrome as a blood-based biomarker for cancer
EP2895623B1 (en) 2012-09-17 2018-08-22 Agios Pharmaceuticals, Inc. Use of e-cadherin and vimentin for selection of treatment responsive patients
US9671405B2 (en) 2012-09-19 2017-06-06 Cornell University Identifying taxane sensitivity in prostate cancer patients
WO2014057490A1 (en) 2012-10-09 2014-04-17 Ramot At Tel-Aviv University Ltd. Methods and kits for predicting prognosis of cancer using soluble mortalin in blood
JP6348115B2 (ja) 2012-10-26 2018-06-27 ザ ユニバーシティー オブ クイーンズランド がん療法のためのエンドサイトーシス阻害剤および抗体の使用
CA2890207A1 (en) 2012-11-05 2014-05-08 Foundation Medicine, Inc. Novel ntrk1 fusion molecules and uses thereof
EP2914622B1 (en) 2012-11-05 2023-06-07 Foundation Medicine, Inc. Novel fusion molecules and uses thereof
HK1214632A1 (zh) 2012-11-05 2016-07-29 Pronai Therapeutics, Inc. 通過調節bcl2表達利用生物標誌物治療癌症的方法
UY35148A (es) 2012-11-21 2014-05-30 Amgen Inc Immunoglobulinas heterodiméricas
CA2892089A1 (en) 2012-11-21 2014-05-30 Rene M. Lemieux Glutaminase inhibitors and methods of use
WO2014079011A1 (en) 2012-11-22 2014-05-30 Agios Pharmaceuticals, Inc. Heterocyclic compounds for inhibiting glutaminase and their methods of use
SI2928476T1 (en) 2012-12-07 2018-06-29 Glycomimetics, Inc. COMPONENTS, INSTALLATIONS AND PROCEDURES OF THE APPLICATION OF E-SELECTINE OF ANTAGONISTS FOR THE MOBILIZATION OF HEMATOPOETIC CELLS
GB201223053D0 (en) 2012-12-20 2013-02-06 Medical Res Council Receptor
WO2014106176A1 (en) 2012-12-28 2014-07-03 Precision Biologics, Inc. Humanized monoclonal antibodies and methods of use for the diagnosis and treatment of colon and pancreas cancer
CA2897053C (en) 2013-01-02 2020-10-13 N-Dia, Inc. Methods for predicting time-to-delivery in pregnant women
CA2897826C (en) 2013-01-09 2022-09-27 Taylor H. Schreiber Compositions and methods for the regulation of t regulatory cells using tl1a-ig fusion protein
EP2945652B1 (en) 2013-01-18 2021-07-07 Foundation Medicine, Inc. Methods of treating cholangiocarcinoma
WO2014122166A1 (en) 2013-02-06 2014-08-14 Pieris Ag Novel lipocalin-mutein assays for measuring hepcidin concentration
ES2685894T3 (es) 2013-03-08 2018-10-15 Pfizer Inc. Polipéptidos de fusión inmunogénicos
US9151747B1 (en) 2013-03-14 2015-10-06 Mercyhurst University Sucralose antibody and immunoassay
US10545140B2 (en) 2013-03-14 2020-01-28 Kasaac Laboratories, Corp. Test strip housing system
US9052314B2 (en) 2013-03-14 2015-06-09 Silver Lake Research Corporation Biomarkers for detecting the presence of bacteria
US9302005B2 (en) 2013-03-14 2016-04-05 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
EP3449977A1 (en) 2013-03-15 2019-03-06 Velo Bio, LLC Method for treating eclampsia and preeclampsia
EP2970980B2 (en) 2013-03-15 2022-07-27 Janssen Biotech, Inc. Manufacturing methods to control c-terminal lysine, galactose and sialic acid content in recombinant proteins
AU2014230447A1 (en) 2013-03-15 2015-09-17 Westfaelische Wilhelms-Universitaet Muenster Detection of acute renal allograft rejection
CN105228641A (zh) 2013-03-21 2016-01-06 密歇根大学董事会 治疗代谢紊乱的方法
GB201305940D0 (en) 2013-04-02 2013-05-15 Immunovia Ab Methods and arrays for use in the same
GB201306147D0 (en) 2013-04-05 2013-05-22 Univ Ha Il Novel biomarker signature and uses thereof
TW201515650A (zh) 2013-05-06 2015-05-01 艾爾妮蘭製藥公司 遞送經脂質調配之核酸分子之劑量及方法
WO2014193804A1 (en) 2013-05-28 2014-12-04 Biogen Idec Ma Inc. Method of assessing risk of pml
EP3003282A1 (en) 2013-06-03 2016-04-13 Novartis AG Combinations of an anti-pd-l1 antibody and a mek inhibitor and/or a braf inhibitor
WO2014195899A1 (en) * 2013-06-06 2014-12-11 Koninklijke Philips N.V. Reagents, methods and devices to prevent aggregation in particle based tests for the detection of multimeric target molecules
EP3013365B1 (en) 2013-06-26 2019-06-05 Academia Sinica Rm2 antigens and use thereof
US9981030B2 (en) 2013-06-27 2018-05-29 Academia Sinica Glycan conjugates and use thereof
WO2015000014A1 (en) 2013-07-01 2015-01-08 Newsouth Innovations Pty Limited Diagnosis and treatment of autoimmune diseases
EP3022303B1 (en) 2013-07-17 2023-11-01 Foundation Medicine, Inc. Methods of treating urothelial carcinomas
US10227370B2 (en) 2013-08-02 2019-03-12 California Institute Of Technology Heparan sulfate/heparin mimetics with anti-chemokine and anti-inflammatory activity
US9770461B2 (en) 2013-08-02 2017-09-26 California Institute Of Technology Tailored glycopolymers as anticoagulant heparin mimetics
US9782476B2 (en) 2013-09-06 2017-10-10 Academia Sinica Human iNKT cell activation using glycolipids with altered glycosyl groups
SG11201601611WA (en) 2013-09-06 2016-04-28 Theranos Inc Systems and methods for detecting infectious diseases
KR20180099912A (ko) 2013-09-08 2018-09-05 화이자 인코포레이티드 나이세리아 메닌지티디스 조성물 및 그의 방법
EP3055695A1 (en) 2013-09-12 2016-08-17 Institut National de la Santé et de la Recherche Médicale Method for in vitro quantifying allo-antibodies, auto-antibodies and/or therapeutic antibodies
JP6546178B2 (ja) 2013-09-13 2019-07-17 ジェネンテック， インコーポレイテッド 細胞株中の宿主細胞タンパク質及び組換えポリペプチド産物を検出及び定量化するための組成物並びに方法
EA034666B1 (ru) 2013-09-13 2020-03-04 Бейджин Свитзерланд Гмбх Антитело против pd-1 и его применение для лечения рака или вирусной инфекции и фрагмент антитела
EP4331605A3 (en) 2013-09-13 2024-05-22 F. Hoffmann-La Roche AG Methods and compositions comprising purified recombinant polypeptides
ES2714708T3 (es) 2013-10-01 2019-05-29 Mayo Found Medical Education & Res Procedimientos para el tratamiento de cáncer en pacientes con niveles elevados de Bim
WO2015050959A1 (en) 2013-10-01 2015-04-09 Yale University Anti-kit antibodies and methods of use thereof
DK3052102T3 (da) 2013-10-04 2020-03-09 Aptose Biosciences Inc Sammensætninger til behandling af cancere
WO2015063604A2 (en) 2013-11-01 2015-05-07 Imberti Luisa BIOMARKERS PREDICTIVE OF THERAPEUTIC RESPONSIVENESS TO IFNβ AND USES THEREOF
GB201319878D0 (en) 2013-11-11 2013-12-25 Immunovia Ab Method, Array and use thereof
CA2928014A1 (en) 2013-11-15 2015-05-21 Institut Pasteur Method for detecting a molecular marker of plasmodium falciparum artemisinin resistance
EP3071217A2 (en) 2013-11-18 2016-09-28 Westfälische Wilhelms-Universität Münster Methods, peptides and antibodies for preventing, treating and diagnosing an inflammatory condition
NZ759287A (en) 2013-12-02 2022-10-28 Baylor College Medicine Identification of a new polypeptide hormone for maintenance of optimal body weight and blood glucose
US9309314B2 (en) 2013-12-03 2016-04-12 Agency For Science, Technology And Research (A*Star) Polypeptides, nucleic acids and uses thereof
GB201322094D0 (en) 2013-12-13 2014-01-29 Electrophoretics Ltd Methods and compositions relating to alzheimers disease
EP3083670A2 (en) 2013-12-17 2016-10-26 Westfälische Wilhelms-Universität Münster Means and methods for treating a pruritus-like skin-disease
EP2960252A1 (en) 2014-06-26 2015-12-30 Institut Pasteur Phospholipase for treatment of immunosuppression
KR102534681B1 (ko) 2013-12-24 2023-05-18 잔센파마슈티카엔.브이. 항-vista 항체 및 단편
US11014987B2 (en) 2013-12-24 2021-05-25 Janssen Pharmaceutics Nv Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
WO2015175340A1 (en) 2014-05-13 2015-11-19 Bavarian Nordic, Inc. Combination therapy for treating cancer with a poxvirus expressing a tumor antigen and a monoclonal antibody against tim-3
ES2728932T3 (es) 2014-01-09 2019-10-29 Intra Cellular Therapies Inc Compuestos orgánicos
EP3091999B2 (en) 2014-01-09 2025-05-07 Hadasit Medical Research Services and Development Ltd. Improved cell compositions and methods for cancer therapy
AU2015206370A1 (en) 2014-01-16 2016-07-07 Academia Sinica Compositions and methods for treatment and detection of cancers
US10150818B2 (en) 2014-01-16 2018-12-11 Academia Sinica Compositions and methods for treatment and detection of cancers
DK3094976T3 (da) 2014-01-17 2020-06-22 Minomic Int Ltd Celleoverfladeprostatakræftantigen til diagnose
BR112016016672A2 (pt) 2014-01-21 2017-08-08 Immune Design Corp Uso de uma composição
MX375123B (es) 2014-02-14 2025-03-06 Immune Design Corp Composición para usarse en mejorar la respuesta inmune contra el cáncer.
GB201403115D0 (en) 2014-02-21 2014-04-09 Qbd Qs Ip Ltd Red blood cell detection
CN106460042A (zh) 2014-02-24 2017-02-22 儿童医院医学中心 用于个性化疼痛管理的方法与组合物
EP3757224A3 (en) 2014-02-27 2021-03-17 Biogen MA Inc. Method of assessing risk of pml
US10000479B2 (en) 2014-03-21 2018-06-19 Agios Pharmaceuticals, Inc. Compounds and their methods of use
WO2015148915A1 (en) 2014-03-27 2015-10-01 Academia Sinica Reactive labelling compounds and uses thereof
SG10201808565QA (en) 2014-03-31 2018-11-29 Debiopharm Int Sa Fgfr fusions
CA2943821A1 (en) 2014-04-02 2015-10-08 Crescendo Bioscience Biomarkers and methods for measuring and monitoring juvenile idiopathic arthritis activity
TWI690521B (zh) 2014-04-07 2020-04-11 美商同步製藥公司 作為隱花色素調節劑之含有咔唑之醯胺類、胺基甲酸酯類及脲類
US9176113B1 (en) 2014-04-11 2015-11-03 Synapdx Corporation Methods and systems for determining autism spectrum disorder risk
EP3134439B1 (en) 2014-04-21 2018-12-26 Millennium Pharmaceuticals, Inc. Anti-psyk antibody molecules and use of same for syk-targeted therapy
US10247729B2 (en) 2014-05-05 2019-04-02 Microbplex, Inc. Media elaborated with newly synthesized antibodies (MENSA) and uses thereof
EP3169365A2 (en) 2014-05-07 2017-05-24 Westfälische Wilhelms-Universität Münster Compounds and methods for the treatment of itch
WO2015172083A1 (en) 2014-05-08 2015-11-12 Biogen Ma Inc. Dimethylfumarate and prodrugs for treatment of multiple sclerosis
EP3143399A1 (en) 2014-05-12 2017-03-22 Biogen MA Inc. Biomarkers predictive of lupus progression and uses thereof
US10302653B2 (en) 2014-05-22 2019-05-28 Mayo Foundation For Medical Education And Research Distinguishing antagonistic and agonistic anti B7-H1 antibodies
CA2950577A1 (en) 2014-05-27 2015-12-03 Academia Sinica Fucosidase from bacteroides and methods using the same
US10118969B2 (en) 2014-05-27 2018-11-06 Academia Sinica Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
AU2015267047A1 (en) 2014-05-27 2017-01-05 Academia Sinica Anti-CD20 glycoantibodies and uses thereof
US10005847B2 (en) 2014-05-27 2018-06-26 Academia Sinica Anti-HER2 glycoantibodies and uses thereof
CN106714829A (zh) 2014-05-28 2017-05-24 中央研究院 抗TNF‑α醣抗体及其用途
GB201410226D0 (en) 2014-06-09 2014-07-23 Immunovia Ab Methods and arrays for use in the same
JP2017523437A (ja) 2014-06-10 2017-08-17 クレッシェンド バイオサイエンス インコーポレイテッド 体軸性脊椎関節炎の疾患活動性を測定およびモニタリングするためのバイオマーカーおよび方法
AU2015274504B2 (en) 2014-06-11 2021-02-04 Kathy A. Green Use of VISTA agonists and antagonists to suppress or enhance humoral immunity
WO2015198334A2 (en) 2014-06-25 2015-12-30 Tel Hashomer Medical Research Infrastructure And Services Ltd. Identification of cancer stem cells and use of same for diagnosis and treatment
FR3023003B1 (fr) 2014-06-27 2016-07-15 Bio-Rad Innovations Combinaison synergique de biomarqueurs pour la detection et l'evaluation d'une fibrose hepatique
AU2015289773A1 (en) 2014-07-15 2017-02-02 Immune Design Corp. Prime-boost regimens with a TLR4 agonist adjuvant and a lentiviral vector
EP3171896A4 (en) 2014-07-23 2018-03-21 Mayo Foundation for Medical Education and Research Targeting dna-pkcs and b7-h1 to treat cancer
CN113846062B (zh) 2014-07-25 2025-02-21 赛拉福柯蒂斯公司 用于嵌合抗原受体分子的调控表达的慢病毒载体
EP3177738B1 (en) 2014-08-08 2019-10-09 Children's Hospital Medical Center Diagnostic method for distinguishing forms of esophageal eosinophilia
RU2730836C2 (ru) 2014-08-14 2020-08-26 Мемед Диагностикс Лтд. Вычислительный анализ биологических данных с применением многообразия и гиперплоскости
WO2016026978A1 (en) 2014-08-22 2016-02-25 Universite Nice Sophia Antipolis Methods and pharmaceutical compositions for treating drug addiction
TWI745275B (zh) 2014-09-08 2021-11-11 中央研究院 使用醣脂激活人類ｉＮＫＴ細胞
US10184154B2 (en) 2014-09-26 2019-01-22 Mayo Foundation For Medical Education And Research Detecting cholangiocarcinoma
WO2016057683A2 (en) 2014-10-07 2016-04-14 Ann And Robert H. Lurie Children's Hospital Of Chicago Novel anti-nodal antibodies and methods of using same
CN114107424A (zh) 2014-10-08 2022-03-01 诺华股份有限公司 预测针对嵌合抗原受体疗法的治疗应答性的生物标志及其用途
GB2555995B (en) 2014-10-20 2019-06-26 Gen Probe Inc Red blood cell lysis solution
US9107906B1 (en) 2014-10-28 2015-08-18 Adma Biologics, Inc. Compositions and methods for the treatment of immunodeficiency
WO2016079219A1 (en) 2014-11-19 2016-05-26 Koninklijke Philips N.V. Diagnostic method employing hnl
CA2969730A1 (en) 2014-12-05 2016-06-09 Immunext, Inc. Identification of vsig8 as the putative vista receptor and its use thereof to produce vista/vsig8 modulators
CN107209184B (zh) 2014-12-11 2020-04-24 米密德诊断学有限公司 用于诊断多种感染的标记组合及其使用方法
MA41142A (fr) 2014-12-12 2017-10-17 Amgen Inc Anticorps anti-sclérostine et utilisation de ceux-ci pour traiter des affections osseuses en tant qu'élements du protocole de traitement
US10495645B2 (en) 2015-01-16 2019-12-03 Academia Sinica Cancer markers and methods of use thereof
US9975965B2 (en) 2015-01-16 2018-05-22 Academia Sinica Compositions and methods for treatment and detection of cancers
EP3248005B1 (en) 2015-01-24 2020-12-09 Academia Sinica Novel glycan conjugates and methods of use thereof
EP3250927B1 (en) 2015-01-28 2020-02-19 H. Hoffnabb-La Roche Ag Gene expression markers and treatment of multiple sclerosis
MX391027B (es) 2015-02-19 2025-03-21 Pfizer Composiciones de neisseria meningitidis y metodos de la misma.
WO2016144824A1 (en) 2015-03-06 2016-09-15 Genentech, Inc. Ultrapurified dsba and dsbc and methods of making and using the same
WO2016149537A1 (en) 2015-03-17 2016-09-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Bank vole prion protein as a broad-spectrum substrate for rt-quic-based detection and discrimination of prion strains
GB201504432D0 (en) 2015-03-17 2015-04-29 Electrophoretics Ltd Materials and methods for diagnosis and treatment of alzheimers disease
US10435755B2 (en) 2015-03-27 2019-10-08 Exact Sciences Development Company, Llc Detecting esophageal disorders
US11279768B1 (en) 2015-04-03 2022-03-22 Precision Biologics, Inc. Anti-cancer antibodies, combination therapies, and uses thereof
US9758575B2 (en) 2015-04-06 2017-09-12 Yung Shin Pharmaceutical Industrial Co. Ltd. Antibodies which specifically bind to canine vascular endothelial growth factor and uses thereof
EP3285811A1 (en) 2015-04-21 2018-02-28 Institut Gustave Roussy Therapeutic methods, products and compositions inhibiting znf555
CN107636014B (zh) 2015-05-04 2021-12-07 皮里斯制药有限公司 抗癌融合多肽
US20180259516A1 (en) 2015-05-04 2018-09-13 Westfälische Wilhelms-Universität Münster Means and methods for diagnosing and treating inflammatory disorders
WO2016181393A1 (en) 2015-05-11 2016-11-17 Yeda Research And Development Co. Ltd. Citrin inhibitors for the treatment of cancer
JP6820278B2 (ja) 2015-05-22 2021-01-27 フアフイ ヘルス リミテッドＨｕａｈｕｉ Ｈｅａｌｔｈ Ｌｔｄ． 抗Ｐｒｅ−Ｓ１ ＨＢＶ抗体
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
CN114805576A (zh) 2015-06-24 2022-07-29 詹森药业有限公司 抗vista抗体和片段
CA2994518A1 (en) 2015-08-25 2017-03-02 Prothena Biosciences Limited Methods for detecting phosphorylated alpha-synuclein
EP3932953A1 (en) 2015-08-28 2022-01-05 F. Hoffmann-La Roche AG Anti-hypusine antibodies and uses thereof
CN108780084B (zh) 2015-09-03 2022-07-22 诺华股份有限公司 预测细胞因子释放综合征的生物标志物
GB201516801D0 (en) 2015-09-22 2015-11-04 Immunovia Ab Method, array and use thereof
MA42924A (fr) 2015-09-23 2018-08-01 Hoffmann La Roche Variants optimisés d'anticorps anti-vegf
WO2017058999A2 (en) 2015-09-29 2017-04-06 Crescendo Bioscience Biomarkers and methods for assessing response to inflammatory disease therapy withdrawal
WO2017059003A1 (en) 2015-09-29 2017-04-06 Crescendo Bioscience Biomarkers and methods for assessing psoriatic arthritis disease activity
AU2016332062A1 (en) 2015-10-01 2018-04-26 Amgen Inc. Treatment of bile acid disorders
AU2016340125B2 (en) 2015-10-15 2021-12-09 Inbios International, Inc. Disabled Multiplexed lateral flow assay systems and methods for their use
US10875923B2 (en) 2015-10-30 2020-12-29 Mayo Foundation For Medical Education And Research Antibodies to B7-H1
CR20180296A (es) 2015-10-30 2018-08-10 Genentech Inc ANTICUERPOS ANTI-HtrA1 Y MÉTODOS DE USO
CA3002196C (en) 2015-10-30 2024-05-14 Exact Sciences Development Company, Llc Multiplex amplification detection assay and isolation and detection of dna from plasma
KR20180073670A (ko) 2015-11-03 2018-07-02 글리코미메틱스, 인크. 암 줄기 세포를 표적화하여 공격성 암을 치료하기 위한 항체
JP2019503985A (ja) 2015-11-03 2019-02-14 グリコミメティクス， インコーポレイテッド モノクローナル抗体、造血幹細胞の産生のための方法および組成物、ならびにそれらを使用する方法
GB201520258D0 (en) 2015-11-17 2015-12-30 Academisch Ziekenhuis Leiden Modulation of ciliogenesis
CN108770366A (zh) 2015-12-15 2018-11-06 凯斯西储大学 β防御素在上皮性癌评估中的应用
EP3402572B1 (en) 2016-01-13 2022-03-16 Children's Hospital Medical Center Compositions and methods for treating allergic inflammatory conditions
EP3410849B1 (en) 2016-02-05 2023-07-05 Institut Pasteur Use of inhibitors of adam12 as adjuvants in tumor therapies
MX2018009800A (es) 2016-02-12 2018-11-09 Janssen Pharmaceutica Nv Anticuerpos y fragmentos anti-vista, usos de los mismos y procedimientos de identificacion de los mismos.
AU2017225854B2 (en) 2016-02-29 2020-11-19 Foundation Medicine, Inc. Therapeutic and diagnostic methods for cancer
CA3015913A1 (en) 2016-02-29 2017-09-08 Foundation Medicine, Inc. Methods of treating cancer
AU2017231749A1 (en) 2016-03-08 2018-09-20 Academia Sinica Methods for modular synthesis of N-glycans and arrays thereof
GB201604124D0 (en) 2016-03-10 2016-04-27 Ucb Biopharma Sprl Pharmaceutical formulation
US10731166B2 (en) 2016-03-18 2020-08-04 Caris Science, Inc. Oligonucleotide probes and uses thereof
GB201700138D0 (en) 2017-01-05 2017-02-22 Senzagen Ab Analytical methods and arrays for use in the same
DK3417074T3 (da) 2016-03-23 2019-09-16 Senzagen Ab Analytiske fremgangsmåder og arrays til bestemmelse af den hudsensibiliserende virkning af midler in vitro
WO2017175058A1 (en) 2016-04-07 2017-10-12 Janssen Pharmaceutica Nv Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
UA125382C2 (uk) 2016-04-15 2022-03-02 Імьюнекст Інк. Антитіла проти людського vista та їх застосування
CA3021343C (en) 2016-04-20 2024-05-28 Crescendo Bioscience Biomarkers and methods for assessing response to inflammatory disease therapy
DE202017007129U1 (de) 2016-04-27 2019-08-29 Gen-Probe Incorporated Lysereagenz für Blutzellen
GB201608192D0 (en) 2016-05-10 2016-06-22 Immunovia Ab Method, array and use thereof
WO2017205686A1 (en) 2016-05-25 2017-11-30 Caris Science, Inc. Oligonucleotide probes and uses thereof
GB201609951D0 (en) 2016-06-07 2016-07-20 Immunovia Ab Biomarkers signatures and uses thereof
GB201609950D0 (en) 2016-06-07 2016-07-20 Immunovia Ab Biomarkers signatures and uses thereof
DK3264087T3 (da) 2016-06-27 2020-07-20 Chimera Biotec Gmbh Fremgangsmåde og indretning til kvantificering af målmolekyler
WO2018001932A1 (en) 2016-06-30 2018-01-04 Koninklijke Philips N.V. Device, system and method for detecting an analyte in a body fluid sample containing a plurality of cells
EP3482201B1 (en) 2016-07-10 2022-12-14 Memed Diagnostics Ltd. Early diagnosis of infections
EP3482200B1 (en) 2016-07-10 2022-05-04 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
US11832801B2 (en) 2016-07-11 2023-12-05 Arizona Board Of Regents On Behalf Of Arizona State University Sweat as a biofluid for analysis and disease identification
CA3033016A1 (en) 2016-08-10 2018-02-15 Institut Pasteur Methods and reagents for detecting piperaquine-resistant plasmodium falciparum malaria
EP4033248B1 (en) 2016-08-10 2024-04-10 MeMed Diagnostics Ltd. System and method for analysis of mx1 and crp in blood
ES2971881T3 (es) 2016-08-19 2024-06-10 Beigene Switzerland Gmbh Combinación de zanubrutinib con un anticuerpo anti-cd20 o anti-pd-1 para su uso en el tratamiento del cáncer
US10538592B2 (en) 2016-08-22 2020-01-21 Cho Pharma, Inc. Antibodies, binding fragments, and methods of use
SG10201912199XA (en) 2016-08-26 2020-02-27 Beigene Ltd Anti-tim-3 antibodies and use thereof
WO2018045162A1 (en) 2016-09-01 2018-03-08 Biogen Ma Inc. Biomarkers predictive of primary progressive multiple sclerosis and uses thereof
EP3510047A1 (en) 2016-09-07 2019-07-17 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. Anti-nkp46 antibodies and therapeutic use of same
WO2018075408A1 (en) 2016-10-17 2018-04-26 Alexion Pharmaceuticals, Inc. Methods of treating acute myeloid leukemia (aml) with combinations of anti-cd200 antibodies, cytarabine, and daunorubicin
WO2018081649A1 (en) 2016-10-28 2018-05-03 Banyan Biomarkers, Inc. Antibodies to ubiquitin c-terminal hydrolase l1 (uch-l1) and glial fibrillary acidic protein (gfap) and related methods
US20180128545A1 (en) 2016-11-08 2018-05-10 Berry Metal Company Modular furnace cooling wall
WO2018102594A1 (en) 2016-12-01 2018-06-07 Alexion Pharmaceuticals, Inc. Methods of treating solid tumors with anti-cd200 antibodies
US10656164B2 (en) 2016-12-22 2020-05-19 Qiagen Sciences, Llc Screening asymptomatic pregnant woman for preterm birth
US10935555B2 (en) 2016-12-22 2021-03-02 Qiagen Sciences, Llc Determining candidate for induction of labor
CN110167967B (zh) 2017-01-18 2022-08-05 豪夫迈·罗氏有限公司 针对抗pd-l1抗体的独特型抗体及其用途
WO2018136728A1 (en) 2017-01-20 2018-07-26 Children's Hospital Medical Center Methods and compositions relating to oprm1 dna methylation for personalized pain management
KR20240074896A (ko) 2017-01-27 2024-05-28 이그젝트 싸이언스 디블롭먼트 컴패니, 엘엘씨 메틸화된 dna 분석에 의한 결장 신조직형성의 검출
GB201701572D0 (en) 2017-01-31 2017-03-15 Immunovia Ab Methods, arrays and uses thereof
PE20191107A1 (es) 2017-01-31 2019-08-26 Pfizer Composiciones de neisseria meningitidis y metodos respectivos
WO2018148180A2 (en) 2017-02-07 2018-08-16 Immune Design Corp. Materials and methods for identifying and treating cancer patients
US11061026B2 (en) 2017-02-17 2021-07-13 MFB Fertility, Inc. System of evaluating corpus luteum function by recurrently evaluating progesterone non-serum bodily fluids on multiple days
US12282029B2 (en) 2017-05-08 2025-04-22 MPB Fertility, Inc. Portable diagnostic system for ovulation cycle monitoring
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection
CN110536969A (zh) 2017-04-24 2019-12-03 豪夫迈·罗氏有限公司 跨膜或近膜域中的erbb2/her2突变
GB201706464D0 (en) 2017-04-24 2017-06-07 Senzagen Ab Analytical methods and arrays for use in the same
EP3618861A1 (en) 2017-05-02 2020-03-11 Bayer Aktiengesellschaft Tmem16a modulation for diagnostic or therapeutic use in pulmonary hypertension (ph)
EP3622291A4 (en) 2017-05-10 2021-04-21 Rowan University Diagnostic biomarkers for detecting, subtyping, and/or assessing progression of multiple sclerosis
WO2019055609A1 (en) 2017-09-14 2019-03-21 University Of Alabama At Birmingham BIOMARKERS AND METHODS OF RISK ASSESSMENT OF MYOCARDIAL INFARCTION AND SEVERE INFECTION IN PATIENTS WITH RHEUMATOID ARTHRITIS
GB201715445D0 (en) 2017-09-25 2017-11-08 Senzagen Ab Novel cell line and uses thereof
US20200225244A1 (en) 2017-09-26 2020-07-16 Sanford Burnham Prebys Medical Discovery Institute Compositions and methods for assessing painful demyelinating and nondemyelinating diseases
WO2019067499A1 (en) 2017-09-27 2019-04-04 Alexion Pharmaceuticals, Inc. BIOMARKER SIGNATURE FOR PREDICTING A TUMOR RESPONSE TO ANTI-CD200 THERAPY
US20200331975A1 (en) 2017-10-20 2020-10-22 Institut Curie Dap10/12 based cars adapted for rush
AU2018358804A1 (en) 2017-11-02 2020-04-09 Bayer Aktiengesellschaft Bispecific antibodies binding ALK-1 and BMPR-2
CA3082365A1 (en) 2017-11-09 2019-05-16 Pinteon Therapeutics Inc. Methods and compositions for the generation and use of humanized conformation-specific phosphorylated tau antibodies
US10648025B2 (en) 2017-12-13 2020-05-12 Exact Sciences Development Company, Llc Multiplex amplification detection assay II
US12139533B2 (en) 2017-12-20 2024-11-12 Alexion Pharmaceuticals, Inc. Liquid formulations of anti-CD200 antibodies
US11802154B2 (en) 2017-12-20 2023-10-31 Alexion Pharmaceuticals, Inc. Humanized anti-CD200 antibodies and uses thereof
EP3727459A2 (en) 2017-12-21 2020-10-28 Friedrich-Alexander-Universität Erlangen-Nürnberg Immunotoxin conjugates for use in therapy
TWI877769B (zh) 2017-12-30 2025-03-21 英屬開曼群島商百濟神州有限公司 抗tigit抗體及其作為治療和診斷的用途
EP3737696A1 (en) 2018-01-12 2020-11-18 Bristol-Myers Squibb Company Combination therapy with anti-il-8 antibodies and anti-pd-1 antibodies for treating cancer
WO2019155474A1 (en) 2018-02-12 2019-08-15 Hadasit Medical Research Services & Development Ltd. Modulation of slamf6 splice variants for cancer therapy
US11859250B1 (en) 2018-02-23 2024-01-02 Children's Hospital Medical Center Methods for treating eosinophilic esophagitis
EP3530282A1 (en) 2018-02-27 2019-08-28 Diaccurate Therapeutic methods
EP3775900A1 (en) 2018-03-26 2021-02-17 Alexion Pharmaceuticals, Inc. High throughput method for measuring the protease activity of complement c3 convertase
CN112166120B (zh) 2018-03-30 2024-09-10 安姆根有限公司 C末端抗体变体
CN112334485B (zh) 2018-04-06 2024-09-27 百进生物科技公司 抗-四次穿膜蛋白33药剂及其组合物以及制备和使用方法
EP3781588B1 (en) 2018-04-20 2024-10-30 Children's Hospital Medical Center Blood biomarker for eosinophilic gastrointestinal disorders
WO2019237119A1 (en) 2018-06-08 2019-12-12 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services New compositions and detection methods for onchocerca volvulus infection
WO2020006179A1 (en) 2018-06-28 2020-01-02 Salaqua Diagnostics, Inc. Compositions and methods associated with haptoglobin related protein
AU2019310040A1 (en) 2018-07-23 2021-02-11 Enclear Therapies, Inc. Methods of treating neurological disorders
EP3826649A4 (en) 2018-07-23 2022-07-20 Enclear Therapies, Inc. Methods of treating neurological disorders
US12181465B2 (en) 2018-08-22 2024-12-31 MFB Fertility, Inc. Method for evaluating urine of a subject to estimate the fertile window by evaluating for the presence of analytes of estrogen and progesterone
WO2020043693A1 (en) 2018-08-29 2020-03-05 Westfälische Wilhelms-Universität Münster Diagnosis of multiple sclerosis
WO2020051277A1 (en) 2018-09-06 2020-03-12 Board Of Regents, The University Of Texas System Treatment and prevention of hemophilic arthropathy with an antibody against endothelial cell protein c receptor (epcr)
JP2022501374A (ja) 2018-09-21 2022-01-06 プレジデント アンド フェローズ オブ ハーバード カレッジ 糖尿病を治療するための方法及び組成物、ならびに分泌タンパク質をコードするｍＲＮＡを濃縮する方法
EP3856343A1 (en) 2018-09-25 2021-08-04 Biolegend, Inc. Anti-tlr9 agents and compositions and methods for making and using the same
DE102018124022A1 (de) 2018-09-28 2020-04-02 Rheinisch-Westfälische Technische Hochschule (Rwth) Aachen Hyaluronsäurestabilisator
AU2019354101A1 (en) 2018-10-05 2021-04-15 Bavarian Nordic A/S Combination therapy for treating cancer with an intravenous administration of a recombinant mva and an immune checkpoint antagonist or agonist
EP3864166A1 (en) 2018-10-12 2021-08-18 Quidel Corporation Extraction reagent for use in an assay for detection of group a streptococcus
WO2020081493A1 (en) 2018-10-16 2020-04-23 Molecular Templates, Inc. Pd-l1 binding proteins
EP3873500A4 (en) 2018-10-31 2023-01-11 Mayo Foundation for Medical Education and Research CANCER TREATMENT METHODS AND MATERIALS
AU2019385665A1 (en) 2018-11-20 2021-05-27 Bavarian Nordic A/S Therapy for treating cancer with an intratumoral and/or intravenous administration of a recombinant MVA encoding 4-1BBL (CD137L) and/or CD40l
CA3121170A1 (en) 2018-11-30 2020-06-04 Caris Mpi, Inc. Next-generation molecular profiling
US20220098310A1 (en) 2018-12-06 2022-03-31 Alexion Pharmaceuticals, Inc. Anti-alk2 antibodies and uses thereof
CA3123717A1 (en) 2019-01-03 2020-07-09 Senzagen Ab Method for identifying agents capable of inducing respiratory sensitization and array and analytical kits for use in the method
WO2020160322A1 (en) 2019-01-30 2020-08-06 Horizon Pharma Rheumatology Llc Tolerization reduces intolerance to pegloticase and prolongs the urate lowering effect (triple)
SG11202107720UA (en) 2019-01-31 2021-08-30 Agency Science Tech & Res Cnx/erp57 inhibitor for use in the treatment or prevention of cancer
EP3693063A1 (en) 2019-02-06 2020-08-12 Diaccurate Methods and compositions for treating cancer
IL264768A (en) 2019-02-10 2020-08-31 Sagi Irit ANTI-MATRIX METALLOPROTEINASE 7 (MMP-7) inhibitory antibody and its use
EA202192146A1 (ru) 2019-02-15 2021-11-09 Интиграл Молекьюлар, Инк. Антитела к клаудину 6 и их применение
EP3924379A4 (en) 2019-02-15 2022-12-21 Integral Molecular, Inc. COMMON LIGHT CHAIN ANTIBODIES AND THEIR USES
US12297501B2 (en) 2019-02-25 2025-05-13 Children's Hospital Medical Center Methods for diagnosing and treating eosinophilic gastritis
US12263192B2 (en) 2019-02-26 2025-04-01 Pantheryx, Inc. Compositions for management of disorders of the gastrointestinal tract
EP3938400B1 (en) 2019-03-11 2025-07-30 Memorial Sloan Kettering Cancer Center Cd22 antibodies and methods of using the same
GB201904472D0 (en) 2019-03-29 2019-05-15 Immunovia Ab Methods, arrays and uses thereof
KR20220011123A (ko) 2019-04-11 2022-01-27 엔클리어 테라피스, 인크. 뇌척수액 개선 방법 및 이를 위한 디바이스 및 시스템
CA3140406A1 (en) 2019-05-28 2020-12-03 Shanghaitech University Composition and methods to treat ectodermal dysplasia 2, clouston type
WO2020261281A1 (en) 2019-06-27 2020-12-30 Ramot At Tel-Aviv University Ltd. Semaphorin 3a antibodies and uses thereof
CN112415184B (zh) 2019-08-22 2025-04-15 香港科技大学 用于细胞群体和单细胞的单分子分离系统及其方法和用途
CN115605222A (zh) 2019-09-27 2023-01-13 辉瑞公司（Us） 脑膜炎奈瑟氏菌组合物及其方法
CN114929740A (zh) 2019-11-11 2022-08-19 Ibi-Ag创新生物杀虫剂有限公司 昆虫防控纳米抗体及其用途
AU2020387646A1 (en) 2019-11-20 2022-05-19 Bavarian Nordic A/S Recombinant MVA viruses for intratumoral and/or intravenous administration for treating cancer
CA3163319A1 (en) 2019-12-02 2021-06-10 Caris Mpi, Inc. Pan-cancer platinum response predictor
US20210188971A1 (en) 2019-12-19 2021-06-24 Quidel Corporation Monoclonal antibody fusions
EP4090681A1 (en) 2020-01-17 2022-11-23 Biolegend, Inc. Anti-tlr7 agents and compositions and methods for making and using the same
WO2021152595A1 (en) 2020-01-29 2021-08-05 Memed Diagnostics Ltd. Methods of diagnosing and classifying viral infections
WO2021188389A2 (en) 2020-03-17 2021-09-23 Genevant Sciences Gmbh Cationic lipids for lipid nanoparticle delivery of therapeutics to hepatic stellate cells
US11815513B2 (en) 2020-04-01 2023-11-14 Institut Pasteur Severe acute respiratory syndrome (SARS)-associated coronavirus diagnostics
US12326451B2 (en) 2020-04-01 2025-06-10 Institut Pasteur Severe acute respiratory syndrome (SARS)—associated coronavirus diagnostics
WO2021209824A1 (en) 2020-04-17 2021-10-21 Institut Pasteur Methods and products for serological analysis of sars-cov-2 infection
JP2023524041A (ja) 2020-04-30 2023-06-08 ジェネンテック， インコーポレイテッド Ｋｒａｓ特異的抗体及びその使用
WO2021239666A1 (en) 2020-05-26 2021-12-02 Diaccurate Therapeutic methods
JP2023530600A (ja) 2020-06-01 2023-07-19 ジェネンテック， インコーポレイテッド 細胞外ベシクルの製造するための方法及びその使用
TW202216771A (zh) 2020-06-26 2022-05-01 德商拜耳廠股份有限公司 用於治療應用之ccr8抗體
CN116600824A (zh) 2020-07-10 2023-08-15 巴斯德研究所 Gdf11诊断和治疗焦虑症和抑郁症的用途
GB202010970D0 (en) 2020-07-16 2020-09-02 Immunovia Ab Methods, arrays and uses thereof
US20240053339A1 (en) 2020-09-21 2024-02-15 Theravectys High throughput methods and products for sars-cov-2 sero-neutralization assay
CA3197180A1 (en) 2020-09-29 2022-04-07 Enclear Therapies, Inc. Subarachnoid fluid management method and system
WO2022093640A1 (en) 2020-10-30 2022-05-05 BioLegend, Inc. Anti-nkg2c agents and compositions and methods for making and using the same
WO2022093641A1 (en) 2020-10-30 2022-05-05 BioLegend, Inc. Anti-nkg2a agents and compositions and methods for making and using the same
WO2022133344A1 (en) 2020-12-18 2022-06-23 Genevant Sciences Gmbh Peg lipids and lipid nanoparticles
PE20241582A1 (es) 2021-01-22 2024-08-01 Bayer Ag Anticuerpos lrrc15 y conjugaddos de los mismos
EP4046652A1 (en) 2021-02-23 2022-08-24 Johann Wolfgang Goethe-Universität Frankfurt Compositions and methods for diagnosing, treating and preventing carrion's disease
EP4298124A1 (en) 2021-02-26 2024-01-03 Bayer Aktiengesellschaft Inhibitors of il-11 or il-11ra for use in the treatment of abnormal uterine bleeding
GB202104422D0 (en) 2021-03-29 2021-05-12 Orre Lukas Methods
WO2022207748A1 (en) 2021-03-30 2022-10-06 Westfälische Wilhelms-Universität Münster Classification of neurological or psychiatric disease manifestations using multi-dimensional cerebrospinal fluid analysis
EP4070814A1 (en) 2021-04-07 2022-10-12 Lama France Sars-cov-2 polypeptides and uses thereof
AR125344A1 (es) 2021-04-15 2023-07-05 Chugai Pharmaceutical Co Ltd Anticuerpo anti-c1s
WO2023118508A1 (en) 2021-12-23 2023-06-29 Bavarian Nordic A/S Recombinant mva viruses for intraperitoneal administration for treating cancer
WO2023144798A1 (en) 2022-01-31 2023-08-03 Genevant Sciences Gmbh Ionizable cationic lipids for lipid nanoparticles
WO2023192478A1 (en) 2022-04-01 2023-10-05 Bristol-Myers Squibb Company Combination therapy with anti-il-8 antibodies and anti-pd-1 antibodies for treating cancer
CN119585444A (zh) 2022-05-18 2025-03-07 巴斯德研究所 人圆环病毒的鉴定
EP4558523A1 (en) 2022-07-19 2025-05-28 Biolegend, Inc. Anti-cd157 antibodies, antigen-binding fragments thereof and compositions and methods for making and using the same
CN119968395A (zh) 2022-08-18 2025-05-09 百进生物科技公司 抗axl抗体、其抗原结合片段及其制备和使用方法
WO2024044675A1 (en) 2022-08-25 2024-02-29 Beigene, Ltd. Methods of cancer treatment using anti-pd1 antibodies in combination with anti-tim3 antibodies
EP4583978A2 (en) 2022-09-09 2025-07-16 Bayer Aktiengesellschaft Medical use of ccr8 antibodies and dosing schedule
WO2024052922A1 (en) 2022-09-11 2024-03-14 Yeda Research And Development Co. Ltd. Anti-klk4 antibodies and uses thereof
AU2023383923A1 (en) 2022-11-24 2025-07-10 Beigene Switzerland Gmbh Anti-cea antibody drug conjugates and methods of use
KR20250114330A (ko) 2022-11-30 2025-07-29 인테그럴 몰큘러 인코포레이티드 클라우딘 6을 표적하는 항체 및 이의 이중특이적 형식
EP4379375A1 (en) 2022-12-01 2024-06-05 Universität Münster Classification of connective tissue disease with neurological manifestation using multi-dimensional peripheral blood analysis
WO2024149703A1 (en) 2023-01-09 2024-07-18 Inserm (Institut National De La Sante Et De La Recherche Medicale) Diagnosis of alzheimer disease
CN120603850A (zh) 2023-01-19 2025-09-05 广州百济神州生物制药有限公司 抗cmet抗体及使用方法
WO2024165468A1 (en) 2023-02-06 2024-08-15 Bayer Aktiengesellschaft Combination of ccr8 antibodies with dgk inhibitors in the treatment of cancer
WO2024183637A1 (en) 2023-03-03 2024-09-12 Beigene Switzerland Gmbh Muc1 antibodies and methods of use
TW202436344A (zh) 2023-03-03 2024-09-16 瑞士商百濟神州瑞士有限責任公司 Ｃｄ１６ａ抗體及使用方法
TW202436343A (zh) 2023-03-03 2024-09-16 瑞士商百濟神州瑞士有限責任公司 Muc1與cd16a抗體以及其使用方法
WO2024184811A1 (en) 2023-03-06 2024-09-12 Beigene Switzerland Gmbh Anti-cd3 multispecific antibodies and methods of use
WO2024184810A1 (en) 2023-03-06 2024-09-12 Beigene Switzerland Gmbh Anti-cldn6 and anti-cd3 multispecific antibodies and methods of use
AR132064A1 (es) 2023-03-06 2025-05-21 Beigene Switzerland Gmbh Anticuerpos anti-cldn6 y métodos de uso
WO2024200655A1 (en) 2023-03-28 2024-10-03 Westfälische Wilhelms-Universität Münster Predictive level of pd-l1 on microvesicles in the evaluation whether being a responder to a treatment of nsclc
WO2024243217A1 (en) 2023-05-25 2024-11-28 BioLegend, Inc. Ceacam6 binding antibodies and antigen-binding fragments thereof
GB2630774A (en) 2023-06-07 2024-12-11 Curenetics Ltd Lung cancer biomarkers
WO2024261762A2 (en) 2023-06-21 2024-12-26 Metasight Diagnostics Ltd Liver fibrosis, nash and "at-risk" nash biomarkers and methods
WO2025008404A1 (en) 2023-07-04 2025-01-09 Universitaet Regensburg In Vertretung Des Freistaates Bayern Use of soluble cd46 concentration from peripheral blood as a parameter for the diagnosis of non-alcoholic fatty liver disease
US12269875B2 (en) 2023-08-03 2025-04-08 Jeff R. Peterson Gout flare prevention methods using IL-1BETA blockers
WO2025052278A1 (en) 2023-09-05 2025-03-13 Genevant Sciences Gmbh Pyrrolidine based cationic lipids for lipid nanoparticle delivery of therapeutics to hepatic stellate cells
EP4527851A1 (en) 2023-09-22 2025-03-26 Bayer Aktiengesellschaft Bispecific antibodies binding ltbr and lrrc15
WO2025072313A1 (en) 2023-09-27 2025-04-03 BioLegend, Inc. Anti-gpc4 antibodies
TW202515903A (zh) 2023-10-12 2025-04-16 瑞士商百濟神州瑞士有限責任公司 手術前後基於抗ｐｄ－１之治療
GB202316762D0 (en) 2023-11-01 2023-12-13 Rna Guardian Ltd Determination of cancer status
WO2025133951A1 (en) 2023-12-21 2025-06-26 Genevant Sciences Gmbh Ionizable lipids suitable for lipid nanoparticles
WO2025146131A1 (en) 2024-01-05 2025-07-10 Beigene, Ltd. ANTI-FGFR2b ANTIBODIES, CONJUGATES AND METHODS OF USE
WO2025154058A1 (en) 2024-01-21 2025-07-24 Ibi-Ag Innovative Bio Insecticides Ltd. Anti-insect hsp70 nanobodies and uses thereof
WO2025154056A1 (en) 2024-01-21 2025-07-24 Ibi-Ag Innovative Bio Insecticides Ltd. Anti-insect cda nanobodies and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654090A (en) * 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
NL154600B (nl) * 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
US3867517A (en) * 1971-12-21 1975-02-18 Abbott Lab Direct radioimmunoassay for antigens and their antibodies
US4016043A (en) * 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
JPS5347518A (en) * 1976-10-07 1978-04-28 Mochida Pharm Co Ltd Immunologically measuring method
US4098876A (en) * 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
NL185309C (nl) * 1980-07-28 1990-03-01 Akzo Nv Methode voor het bepalen van antigenen met behulp van twee of meer monoklonale antilichamen alsmede immuunreagens.
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies

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