BR112014002141A2 - crizotinib para uso no tratamento de câncer - Google Patents

crizotinib para uso no tratamento de câncer

Info

Publication number
BR112014002141A2
BR112014002141A2 BR112014002141A BR112014002141A BR112014002141A2 BR 112014002141 A2 BR112014002141 A2 BR 112014002141A2 BR 112014002141 A BR112014002141 A BR 112014002141A BR 112014002141 A BR112014002141 A BR 112014002141A BR 112014002141 A2 BR112014002141 A2 BR 112014002141A2
Authority
BR
Brazil
Prior art keywords
crizotinib
cancer treatment
cancer
treatment
provides methods
Prior art date
Application number
BR112014002141A
Other languages
English (en)
Inventor
Gail Christensen James
Zou Yahong
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BR112014002141A2 publication Critical patent/BR112014002141A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

resumo patente de invenção: "crizotinib para uso no tratamento de câncer". a presente invenção refere-se à utilização de inibidores de ros quinase para o tratamento de crescimento de célula anormal em mamíferos. em particular, a invenção proporciona métodos de tratamento de mamíferos que sofrem de câncer mediado por, pelo menos, um ros geneticamente alterado. em particular, a invenção proporciona métodos de tratamento de mamíferos que sofrem de câncer mediado por, pelo menos, um ros geneticamente alterado pela administração de crizotinib.
BR112014002141A 2011-08-02 2012-07-24 crizotinib para uso no tratamento de câncer BR112014002141A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161514386P 2011-08-02 2011-08-02
PCT/IB2012/053765 WO2013017989A1 (en) 2011-08-02 2012-07-24 Crizotinib for use in the treatment of cancer

Publications (1)

Publication Number Publication Date
BR112014002141A2 true BR112014002141A2 (pt) 2017-02-21

Family

ID=46845786

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014002141A BR112014002141A2 (pt) 2011-08-02 2012-07-24 crizotinib para uso no tratamento de câncer

Country Status (15)

Country Link
US (1) US20160206608A1 (pt)
EP (1) EP2739284A1 (pt)
JP (1) JP2013032355A (pt)
KR (1) KR20140041906A (pt)
CN (1) CN103841972A (pt)
AR (1) AR087731A1 (pt)
AU (1) AU2012291744A1 (pt)
BR (1) BR112014002141A2 (pt)
CA (1) CA2842493A1 (pt)
HK (1) HK1198133A1 (pt)
IL (1) IL230698A0 (pt)
MX (1) MX2014001354A (pt)
RU (1) RU2014102935A (pt)
TW (1) TW201313698A (pt)
WO (1) WO2013017989A1 (pt)

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CA2744236C (en) 2009-02-12 2021-03-16 Cell Signaling Technology, Inc. Mutant ros expression in human cancer
AU2013268400B2 (en) 2012-05-30 2017-07-13 Nippon Shinyaku Co., Ltd. Aromatic heterocyclic derivative and pharmaceutical
EP2764866A1 (en) 2013-02-07 2014-08-13 IP Gesellschaft für Management mbH Inhibitors of nedd8-activating enzyme
ITMI20131124A1 (it) 2013-07-04 2015-01-05 Univ Milano Bicocca 2-acilamminotiazoli per il trattamento del cancro
KR101538385B1 (ko) * 2013-09-02 2015-07-29 가톨릭대학교 산학협력단 크리조티닙을 포함하는 톡소포자충 감염증의 예방 및 치료용 조성물
WO2015144799A1 (en) * 2014-03-27 2015-10-01 Janssen Pharmaceutica Nv SUBSTITUTED 4,5,6,7-TETRAHYDRO-PYRAZOLO[1,5-a]PYRAZINE DERIVATIVES AND 5,6,7,8-TETRAHYDRO-4H-PYRAZOLO[1,5-a][1,4]DIAZEPINE DERIVATIVES AS ROS1 INHIBITORS
US10695426B2 (en) 2014-08-25 2020-06-30 Pfizer Inc. Combination of a PD-1 antagonist and an ALK inhibitor for treating cancer
WO2017058780A1 (en) 2015-09-30 2017-04-06 Merck Patent Gmbh Combination of a pd-1 axis binding antagonist and an alk inhibitor for treating alk-negative cancer
WO2017201502A1 (en) 2016-05-20 2017-11-23 Biohaven Pharmaceutical Holding Company Ltd. Use of glutamate modulating agents with immunotherapies to treat cancer
US20220033402A1 (en) * 2018-09-27 2022-02-03 Dana-Farber Cancer Institute, Inc. Macrocyclic inhibitors of alk, trka, trkb, and ros1
KR20210100557A (ko) 2020-02-06 2021-08-17 웰마커바이오 주식회사 Kras 돌연변이와 관련된 암의 예방 또는 치료용 약학 조성물
EP4115887A1 (en) 2020-03-03 2023-01-11 Wellmarker Bio Co., Ltd. Pharmaceutical composition for prevention or treatment of cancer in which kras mutation and activated ron are present
CN113493437B (zh) * 2020-04-03 2022-07-26 中国药科大学 含苯并咪唑结构的化合物及其制备方法和用途
WO2021196655A1 (zh) * 2020-04-03 2021-10-07 中国药科大学 含苯并咪唑结构的化合物及其制备方法与用途
CN111518769A (zh) * 2020-05-13 2020-08-11 四川大学华西医院 一种克唑替尼获得性耐药肺腺癌细胞系的建立方法

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US4659678A (en) 1982-09-29 1987-04-21 Serono Diagnostics Limited Immunoassay of antigens
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US5376645A (en) 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
GB9518953D0 (en) 1995-09-15 1995-11-15 Pfizer Ltd Pharmaceutical formulations
WO2000035296A1 (en) 1996-11-27 2000-06-22 Wm. Wrigley Jr. Company Improved release of medicament active agents from a chewing gum coating
GB9711643D0 (en) 1997-06-05 1997-07-30 Janssen Pharmaceutica Nv Glass thermoplastic systems
US6573043B1 (en) 1998-10-07 2003-06-03 Genentech, Inc. Tissue analysis and kits therefor
DK1603570T5 (da) 2003-02-26 2013-12-09 Sugen Inc Aminoheteroarylforbindelser som proteinkinaseinhibitorer
ME01309B (me) * 2004-08-26 2013-12-20 Pfizer Pirazolom supstituirani heteroarilni spojevi kao inhibitori proteinskih kinaza
JP4242911B2 (ja) 2004-08-26 2009-03-25 ファイザー・インク プロテインキナーゼ阻害薬としてのエナンチオピュアなアミノヘテロアリール化合物
EP3360965A1 (en) 2006-01-20 2018-08-15 Cell Signaling Technology, Inc. Translocation and mutant ros kinase in human non-small cell lung carcinoma
EP3072963B1 (en) 2007-10-18 2020-04-01 Cell Signaling Technology, Inc. Translocation and mutant ros kinase in human non-small cell lung carcinoma
CA2744236C (en) 2009-02-12 2021-03-16 Cell Signaling Technology, Inc. Mutant ros expression in human cancer

Also Published As

Publication number Publication date
EP2739284A1 (en) 2014-06-11
TW201313698A (zh) 2013-04-01
CN103841972A (zh) 2014-06-04
KR20140041906A (ko) 2014-04-04
AR087731A1 (es) 2014-04-16
US20160206608A1 (en) 2016-07-21
MX2014001354A (es) 2014-10-14
JP2013032355A (ja) 2013-02-14
HK1198133A1 (en) 2015-03-13
AU2012291744A1 (en) 2014-02-20
CA2842493A1 (en) 2013-02-07
WO2013017989A1 (en) 2013-02-07
IL230698A0 (en) 2014-03-31
RU2014102935A (ru) 2015-09-10

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]