DE69939374D1 - Zu vegf und bmp1 homologe polypeptide - Google Patents
Zu vegf und bmp1 homologe polypeptideInfo
- Publication number
- DE69939374D1 DE69939374D1 DE69939374T DE69939374T DE69939374D1 DE 69939374 D1 DE69939374 D1 DE 69939374D1 DE 69939374 T DE69939374 T DE 69939374T DE 69939374 T DE69939374 T DE 69939374T DE 69939374 D1 DE69939374 D1 DE 69939374D1
- Authority
- DE
- Germany
- Prior art keywords
- vegf
- bmp1
- homologous polypeptides
- growth factor
- vascular endothelial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/040,220 US6391311B1 (en) | 1998-03-17 | 1998-03-17 | Polypeptides having homology to vascular endothelial cell growth factor and bone morphogenetic protein 1 |
US18421698A | 1998-11-02 | 1998-11-02 | |
PCT/US1999/005190 WO1999047677A2 (en) | 1998-03-17 | 1999-03-10 | Polypeptides homologous to vegf and bmp1 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69939374D1 true DE69939374D1 (de) | 2008-10-02 |
Family
ID=26716852
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69939374T Expired - Lifetime DE69939374D1 (de) | 1998-03-17 | 1999-03-10 | Zu vegf und bmp1 homologe polypeptide |
Country Status (14)
Country | Link |
---|---|
US (11) | US6455283B1 (de) |
EP (2) | EP1064382B1 (de) |
JP (3) | JP4532733B2 (de) |
AT (1) | ATE405651T1 (de) |
AU (1) | AU758353B2 (de) |
CA (1) | CA2322792C (de) |
CY (2) | CY1108500T1 (de) |
DE (1) | DE69939374D1 (de) |
DK (2) | DK1064382T3 (de) |
ES (2) | ES2389387T3 (de) |
HK (1) | HK1125853A1 (de) |
IL (5) | IL138488A0 (de) |
PT (1) | PT2016951E (de) |
WO (1) | WO1999047677A2 (de) |
Families Citing this family (62)
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---|---|---|---|---|
WO2001052904A2 (en) * | 2000-01-19 | 2001-07-26 | Gill Parkash S | Pharmaceutical compositions and methods of treatment based on vegf antisense oligonucleotides |
DE69933856D1 (de) | 1998-02-13 | 2006-12-14 | Koester Hubert | Verwendung von ribozymen zur bestimmung der funktion von genen |
EP1059891A4 (de) * | 1998-03-06 | 2004-05-19 | Crosscart Inc | Xenotransplantate aus weichem gewebe |
EP1064382B1 (de) | 1998-03-17 | 2008-08-20 | Genentech, Inc. | Zu vegf und bmp1 homologe polypeptide |
EP0984063A3 (de) * | 1998-08-31 | 2000-08-16 | Eli Lilly And Company | Vegf-verwandtes gen und protein |
US6432673B1 (en) | 1998-12-07 | 2002-08-13 | Zymogenetics, Inc. | Growth factor homolog ZVEGF3 |
US6663870B2 (en) * | 1998-12-07 | 2003-12-16 | Zymogenetics, Inc. | Methods for promoting growth of bone using zvegf3 |
DE69939330D1 (de) * | 1998-12-07 | 2008-09-25 | Zymogenetics Inc | Wachstumsfaktor-homologe zvegf-3 |
US6783953B1 (en) | 1998-12-22 | 2004-08-31 | Janssen Pharmaceutica N.V. | Vascular endothelial growth factor-X |
ES2291047T3 (es) * | 1998-12-22 | 2008-02-16 | Janssen Pharmaceutica N.V. | Factor de crecimiento del endotelio vascular-x. |
WO2000039284A1 (en) * | 1998-12-30 | 2000-07-06 | Millennium Pharmaceuticals, Inc. | Secreted proteins and nucleic acids encoding them |
CA2362427A1 (en) * | 1999-03-08 | 2000-09-14 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
AU3737500A (en) * | 1999-03-12 | 2000-09-28 | Genentech Inc. | Method of preventing the death of retinal neurons and treating ocular diseases |
AU4008500A (en) * | 1999-04-06 | 2000-10-23 | Eli Lilly And Company | Platelet-derived growth factor related gene and protein |
US6630142B2 (en) | 1999-05-03 | 2003-10-07 | Zymogenetics, Inc. | Method of treating fibroproliferative disorders |
EP1222279A2 (de) * | 1999-10-07 | 2002-07-17 | Curagen Corporation | Wachstumsfaktorenpolypeptide und nukleinsäuren die dafür kodieren |
AU8031700A (en) * | 1999-10-21 | 2001-04-30 | Zymogenetics Inc. | Method of treating fibrosis |
US6893637B1 (en) * | 1999-10-21 | 2005-05-17 | Zymogenetics, Inc. | Method of treating fibrosis |
AU1430601A (en) * | 1999-11-02 | 2001-05-14 | Eli Lilly And Company | Methods of using lp8, a pdgf-related protein, to treat musculoskeletal disorders |
US7141607B1 (en) | 2000-03-10 | 2006-11-28 | Insite Vision Incorporated | Methods and compositions for treating and inhibiting retinal neovascularization |
AU2001249525A1 (en) * | 2000-03-28 | 2001-10-08 | Ludwig Institute For Cancer Research | Non-human transgenic animals expressing platelet-derived growth factor C (PDGF-C) and uses thereof |
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EP1604024A4 (de) * | 2000-04-06 | 2008-04-23 | Wayne P Franco | Verfahren zur verwendung von wachstumsfaktoren zur behandlung von herzerkrankungen |
US7166280B2 (en) * | 2000-04-06 | 2007-01-23 | Franco Wayne P | Combination growth factor therapy and cell therapy for treatment of acute and chronic heart disease |
US20050277576A1 (en) * | 2000-04-06 | 2005-12-15 | Franco Wayne P | Combination growth factor therapy and cell therapy for treatment of acute and chronic diseases of the organs |
US20070111935A1 (en) * | 2000-04-06 | 2007-05-17 | Franco Wayne P | Combination growth factor therapy and cell therapy for treatment of acute and chronic diseases of the organs |
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ES2260234T3 (es) * | 2000-05-12 | 2006-11-01 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw. | Utilizacion de inhibidores del factor de crecimiento placentario para el tratamiento de la angiogenesis patologica, de la arteriogenesis patologica, de la inflamacion, de la formacion tumoral y/o de la perdida vascular. |
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CN1602207A (zh) * | 2001-12-11 | 2005-03-30 | 法布罗根股份有限公司 | 抑制眼病理过程的方法 |
AU2003217531A1 (en) * | 2002-05-02 | 2003-11-17 | Massachusetts Eye And Ear Infirmary | Ocular drug delivery systems and use thereof |
EP1501357A4 (de) * | 2002-05-06 | 2009-10-21 | Genentech Inc | Verwendung von vegf für die behandlung von knochendefekten |
WO2003105842A1 (en) * | 2002-06-13 | 2003-12-24 | Novuspharma S.P.A. | Derivatives of chromen-2-one as inhibitors of vegf production in mammalian cells |
US20040052161A1 (en) * | 2002-09-17 | 2004-03-18 | Steven Liao | Mechanical clock having wireless manipulation and adjustment function |
ES2305541T3 (es) | 2002-11-16 | 2008-11-01 | Dade Behring Marburg Gmbh | Scd40l, papp-a y factor de crecimiento placentario (pigf) como combinaciones de marcadores bioquimicos en enfermedades cardiovasculares. |
US20090155266A1 (en) * | 2004-01-16 | 2009-06-18 | Yale University | Methods and Compositions Relating to Vascular Endothelial Growth Factor and TH2 Mediated Inflammatory Diseases |
WO2005087177A2 (en) * | 2004-03-05 | 2005-09-22 | Ludwig Institute For Cancer Research | Chimeric anti-vegf-d antibodies and humanized anti-vegf-d antibodies and methods of using same |
US20050282233A1 (en) * | 2004-03-05 | 2005-12-22 | Ludwig Institute For Cancer Research | Multivalent antibody materials and methods for VEGF/PDGF family of growth factors |
US8415315B2 (en) | 2004-05-06 | 2013-04-09 | University Of Central Florida Research Foundation, Inc. | Methods and compositions for inhibiting the proliferation of cancer cells |
ES2351804T3 (es) | 2004-05-27 | 2011-02-10 | Vib, Vzw | Tratamiento de esclerosis lateral amiotrófica. |
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ES2429225T3 (es) | 2006-05-17 | 2013-11-13 | The Ludwig Institute For Cancer Research | Anticuerpos anti VEGF-B para tratamiento o profilaxis de diabetes de tipo II o síndrome metabólico |
ES2354922B1 (es) | 2009-09-02 | 2012-02-07 | Fundacion Institut De Recerca De L'hospital Universitari Vall D'hebron | Marcadores para la selección de terapias personalizadas para el tratamiento del c�?ncer. |
TW201302793A (zh) | 2010-09-03 | 2013-01-16 | Glaxo Group Ltd | 新穎之抗原結合蛋白 |
EA018848B1 (ru) * | 2010-10-20 | 2013-11-29 | Вадим Юльевич ШАНИН | Иммунологически активное вещество, способ его получения, биозонд на его основе и способ диагностики состояния здоровья с применением биозонда, фармацевтическая композиция и способ лечения с использованием фармацевтической композиции |
WO2013079713A1 (en) | 2011-12-01 | 2013-06-06 | Thrombogenics Nv | Improving trabeculectomy outcome |
KR20150005631A (ko) | 2012-04-24 | 2015-01-14 | 쓰롬보제닉스 엔.브이. | 항-pdgf-c 항체 |
CN104768567B (zh) * | 2012-05-18 | 2017-07-11 | 奥塔哥创业有限公司 | 用于伤口愈合的联合治疗和组合物 |
US20160024181A1 (en) | 2013-03-13 | 2016-01-28 | Moderna Therapeutics, Inc. | Long-lived polynucleotide molecules |
CN105713095B (zh) * | 2016-03-14 | 2021-05-07 | 南京安吉生物科技有限公司 | 一种多功能融合多肽及其制备方法和应用 |
KR101943081B1 (ko) | 2017-08-31 | 2019-01-29 | (주)케어젠 | 주름 개선 활성을 나타내는 펩타이드 및 이의 용도 |
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