IN2012DN00943A - - Google Patents

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Publication number
IN2012DN00943A
IN2012DN00943A IN943DEN2012A IN2012DN00943A IN 2012DN00943 A IN2012DN00943 A IN 2012DN00943A IN 943DEN2012 A IN943DEN2012 A IN 943DEN2012A IN 2012DN00943 A IN2012DN00943 A IN 2012DN00943A
Authority
IN
India
Prior art keywords
chemical entities
kinase activity
treatin
modulate
diseases
Prior art date
Application number
Other languages
English (en)
Inventor
Ren Pingda
Liu Yi
Edward Wilson Troy
Li Liansheng
Chan Katrina
Rommel Christian
Original Assignee
Intellikine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intellikine Inc filed Critical Intellikine Inc
Publication of IN2012DN00943A publication Critical patent/IN2012DN00943A/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/36—Sulfur atom
    • C07D473/38—Sulfur atom attached in position 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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    • A61K31/131—Amines acyclic
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
IN943DEN2012 2009-07-15 2010-07-28 IN2012DN00943A (enEXAMPLES)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/503,776 US8193182B2 (en) 2008-01-04 2009-07-15 Substituted isoquinolin-1(2H)-ones, and methods of use thereof
PCT/US2010/002020 WO2011008302A1 (en) 2009-07-15 2010-07-15 Certain chemical entities, compositions and methods

Publications (1)

Publication Number Publication Date
IN2012DN00943A true IN2012DN00943A (enEXAMPLES) 2015-04-10

Family

ID=43450336

Family Applications (1)

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IN943DEN2012 IN2012DN00943A (enEXAMPLES) 2009-07-15 2010-07-28

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US (13) US8193182B2 (enEXAMPLES)
EP (4) EP3150609B1 (enEXAMPLES)
JP (2) JP5944313B2 (enEXAMPLES)
KR (1) KR101680406B1 (enEXAMPLES)
CN (3) CN102711767B (enEXAMPLES)
AU (1) AU2010274075B2 (enEXAMPLES)
BR (1) BR112012000968B8 (enEXAMPLES)
CA (1) CA2768307C (enEXAMPLES)
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DK (1) DK2456444T3 (enEXAMPLES)
ES (1) ES2538853T3 (enEXAMPLES)
FI (1) FIC20210039I1 (enEXAMPLES)
HR (1) HRP20150586T1 (enEXAMPLES)
HU (1) HUS2100048I1 (enEXAMPLES)
IL (2) IL217181A (enEXAMPLES)
IN (1) IN2012DN00943A (enEXAMPLES)
LT (1) LTC2456444I2 (enEXAMPLES)
LU (1) LUC00237I2 (enEXAMPLES)
MX (3) MX379814B (enEXAMPLES)
MY (2) MY175979A (enEXAMPLES)
NL (1) NL301140I2 (enEXAMPLES)
NO (1) NO2021047I1 (enEXAMPLES)
NZ (3) NZ706506A (enEXAMPLES)
PH (2) PH12015502432A1 (enEXAMPLES)
PL (1) PL2456444T3 (enEXAMPLES)
PT (1) PT2456444E (enEXAMPLES)
RU (2) RU2746319C2 (enEXAMPLES)
SG (2) SG10201503886WA (enEXAMPLES)
SI (1) SI2456444T1 (enEXAMPLES)
SM (1) SMT201500141B (enEXAMPLES)
UA (2) UA109878C2 (enEXAMPLES)
WO (1) WO2011008302A1 (enEXAMPLES)
ZA (1) ZA201200254B (enEXAMPLES)

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AU2004203682B2 (en) * 2003-01-06 2009-10-01 Angiochem Inc. Aprotinin and analogs as carriers across the blood-brain barrier
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IL243932A0 (en) 2016-04-21
JP2012533541A (ja) 2012-12-27
JP2016210781A (ja) 2016-12-15
US8193182B2 (en) 2012-06-05
EP3150609A1 (en) 2017-04-05
BR112012000968A2 (pt) 2017-12-05
CY2021034I2 (el) 2022-03-24
US20250170122A1 (en) 2025-05-29
RU2582676C3 (ru) 2022-01-17
SMT201500141B (it) 2015-09-07
US20200222384A1 (en) 2020-07-16

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