SG11202106635WA - Combination of antibody-drug conjugate and kinase inhibitor - Google Patents

Combination of antibody-drug conjugate and kinase inhibitor

Info

Publication number
SG11202106635WA
SG11202106635WA SG11202106635WA SG11202106635WA SG11202106635WA SG 11202106635W A SG11202106635W A SG 11202106635WA SG 11202106635W A SG11202106635W A SG 11202106635WA SG 11202106635W A SG11202106635W A SG 11202106635WA SG 11202106635W A SG11202106635W A SG 11202106635WA
Authority
SG
Singapore
Prior art keywords
antibody
combination
kinase inhibitor
drug conjugate
conjugate
Prior art date
Application number
SG11202106635WA
Inventor
Chiaki Ishii
Yasuki Kamai
Kiyoshi Sugihara
Daisuke Okajima
Yuuri HASHIMOTO
Hirokazu Suzuki
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of SG11202106635WA publication Critical patent/SG11202106635WA/en

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Classifications

    • A—HUMAN NECESSITIES
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    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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    • A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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