|
CN104356236B
(zh)
*
|
2005-07-01 |
2020-07-03 |
E.R.施贵宝&圣斯有限责任公司 |
抗程序性死亡配体1(pd-l1)的人单克隆抗体
|
|
TW202442680A
(zh)
|
2008-12-09 |
2024-11-01 |
美商建南德克公司 |
抗pd-l1抗體及其於增進t細胞功能之用途
|
|
US8741591B2
(en)
|
2009-10-09 |
2014-06-03 |
The Research Foundation For The State University Of New York |
pH-insensitive glucose indicator protein
|
|
CN103517990A
(zh)
|
2010-10-07 |
2014-01-15 |
通用医疗公司 |
癌症生物标志物
|
|
EP2655409A4
(en)
|
2010-12-22 |
2015-07-01 |
Univ Leland Stanford Junior |
SUPERAGONISTS AND ANTAGONISTS OF INTERLEUKIN-2
|
|
EP2537933A1
(en)
|
2011-06-24 |
2012-12-26 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
An IL-15 and IL-15Ralpha sushi domain based immunocytokines
|
|
PT3409278T
(pt)
|
2011-07-21 |
2020-12-18 |
Sumitomo Dainippon Pharma Oncology Inc |
Inibidores de proteína cinase heterocíclicos
|
|
MX349096B
(es)
|
2011-11-28 |
2017-07-11 |
Merck Patent Gmbh |
Anticuerpos anti-pd-l1 y sus usos.
|
|
EP2855528B1
(en)
*
|
2012-05-31 |
2019-06-19 |
Genentech, Inc. |
Methods of treating cancer using pd-l1 axis binding antagonists and vegf antagonists
|
|
MX2015007051A
(es)
|
2012-12-07 |
2016-01-12 |
Chemocentryx Inc |
Diazol lactamas.
|
|
EP3640375A3
(en)
*
|
2012-12-11 |
2020-07-29 |
Albert Einstein College of Medicine |
Methods for high throughput receptor/ligand identification
|
|
DK2944323T3
(en)
|
2013-01-11 |
2019-04-15 |
Dingfu Biotarget Co Ltd |
Means for the treatment of tumors, their use and their method
|
|
MY176706A
(en)
|
2013-03-15 |
2020-08-19 |
Genentech Inc |
Biomarkers and methods of treating pd-1 and pd-l1 related conditions
|
|
AR095882A1
(es)
|
2013-04-22 |
2015-11-18 |
Hoffmann La Roche |
Terapia de combinación de anticuerpos contra csf-1r humano con un agonista de tlr9
|
|
BR112015028326A8
(pt)
|
2013-06-03 |
2018-01-23 |
Novartis Ag |
combinações de anticorpo anti-pd-l1, inibidor de mek e/ou inibidor de braf, seus kits e seus usos, e composição farmacêutica
|
|
KR102661249B1
(ko)
*
|
2013-09-11 |
2024-04-25 |
메디뮨 리미티드 |
종양 치료용 항-b7-h1 항체
|
|
AR097584A1
(es)
*
|
2013-09-12 |
2016-03-23 |
Hoffmann La Roche |
Terapia de combinación de anticuerpos contra el csf-1r humano y anticuerpos contra el pd-l1 humano
|
|
EA034666B1
(ru)
|
2013-09-13 |
2020-03-04 |
Бейджин Свитзерланд Гмбх |
Антитело против pd-1 и его применение для лечения рака или вирусной инфекции и фрагмент антитела
|
|
CN105722860A
(zh)
|
2013-09-24 |
2016-06-29 |
梅迪塞纳医疗股份有限公司 |
白介素-2融合蛋白及其应用
|
|
EP3049442A4
(en)
|
2013-09-26 |
2017-06-28 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
|
EP4285928A3
(en)
*
|
2013-09-27 |
2024-03-13 |
F. Hoffmann-La Roche AG |
Anti-pdl1 antibody formulations
|
|
US10202454B2
(en)
*
|
2013-10-25 |
2019-02-12 |
Dana-Farber Cancer Institute, Inc. |
Anti-PD-L1 monoclonal antibodies and fragments thereof
|
|
WO2015066413A1
(en)
|
2013-11-01 |
2015-05-07 |
Novartis Ag |
Oxazolidinone hydroxamic acid compounds for the treatment of bacterial infections
|
|
SG10201808519VA
(en)
*
|
2013-12-17 |
2018-10-30 |
Genentech Inc |
Methods of treating her2-positive cancers using pd-1 axis binding antagonists and anti-her2 antibodies
|
|
EA032469B1
(ru)
|
2013-12-24 |
2019-05-31 |
Бристол-Маерс Сквибб Компани |
Новые трициклические соединения в качестве противораковых средств
|
|
US20160340407A1
(en)
*
|
2014-01-14 |
2016-11-24 |
Dana-Farber Camcer Institute, Inc. |
Compositions and methods for identification, assessment, prevention, and treatment of melanoma using pd-l1 isoforms
|
|
WO2015109124A2
(en)
*
|
2014-01-15 |
2015-07-23 |
Kadmon Corporation, Llc |
Immunomodulatory agents
|
|
JO3517B1
(ar)
|
2014-01-17 |
2020-07-05 |
Novartis Ag |
ان-ازاسبيرو الكان حلقي كبديل مركبات اريل-ان مغايرة وتركيبات لتثبيط نشاط shp2
|
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對pd-1的人類抗體
|
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗pd-l1之人類抗體
|
|
US10441654B2
(en)
|
2014-01-24 |
2019-10-15 |
Children's Hospital Of Eastern Ontario Research Institute Inc. |
SMC combination therapy for the treatment of cancer
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
DK3105246T3
(da)
|
2014-02-10 |
2021-06-14 |
Merck Patent Gmbh |
Målrettet TGF-beta-inhibering
|
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
|
KR102442436B1
(ko)
|
2014-03-14 |
2022-09-15 |
노파르티스 아게 |
Lag-3에 대한 항체 분자 및 그의 용도
|
|
UA121383C2
(uk)
|
2014-03-24 |
2020-05-25 |
Новартіс Аг |
Органічні сполуки, що є монобактамами, для лікування бактеріальних інфекцій
|
|
CN106659757B
(zh)
|
2014-04-24 |
2022-01-28 |
利兰斯坦福初级大学董事会 |
白介素2的超级激动剂、部分激动剂和拮抗剂
|
|
CA2949121A1
(en)
|
2014-05-15 |
2015-11-19 |
Bristol-Myers Squibb Company |
Treatment of lung cancer using a combination of an anti-pd-1 antibody and another anti-cancer agent
|
|
ES2753360T3
(es)
|
2014-05-29 |
2020-04-08 |
Spring Bioscience Corp |
Anticuerpos contra PD-L1 y usos de los mismos
|
|
PT3151921T
(pt)
|
2014-06-06 |
2019-11-21 |
Bristol Myers Squibb Co |
Anticorpos contra recetor do fator de necrose tumoral induzido por glicocorticoide e utilizações dos mesmos
|
|
EP3151820A4
(en)
|
2014-06-06 |
2017-11-22 |
Flexus Biosciences, Inc. |
Immunoregulatory agents
|
|
US10092645B2
(en)
*
|
2014-06-17 |
2018-10-09 |
Medimmune Limited |
Methods of treatment with antagonists against PD-1 and PD-L1 in combination with radiation therapy
|
|
EP3760208B1
(en)
|
2014-06-25 |
2024-05-29 |
The General Hospital Corporation |
Targeting human satellite ii (hsatii)
|
|
KR102130600B1
(ko)
*
|
2014-07-03 |
2020-07-08 |
베이진 엘티디 |
Pd-l1 항체와 이를 이용한 치료 및 진단
|
|
DK3166976T3
(da)
|
2014-07-09 |
2022-04-11 |
Birdie Biopharmaceuticals Inc |
Anti-pd-l1-kombinationer til behandling af tumorer
|
|
EP3166616B1
(en)
*
|
2014-07-10 |
2021-04-07 |
Biothera, Inc. |
Beta-glucan in combination with anti-cancer agents affecting the tumor microenvironment
|
|
ES2916923T3
(es)
|
2014-07-11 |
2022-07-06 |
Ventana Med Syst Inc |
Anticuerpos anti-PD-L1 y usos diagnósticos de los mismos
|
|
BR122020025583B1
(pt)
|
2014-07-22 |
2023-12-05 |
Cb Therapeutics, Inc |
Anticorpo isolado ou fragmento do mesmo que liga a pd-1, uso deste, composição, polinucleotídeo isolado e vetor de expressão
|
|
EP3195168B1
(en)
*
|
2014-07-31 |
2022-09-07 |
The University Of Western Australia |
A method for the identification of immunotherapy-drug combinations using a network approach
|
|
US10435470B2
(en)
*
|
2014-08-05 |
2019-10-08 |
Cb Therapeutics, Inc. |
Anti-PD-L1 antibodies
|
|
WO2016020836A1
(en)
|
2014-08-06 |
2016-02-11 |
Novartis Ag |
Quinolone derivatives as antibacterials
|
|
HRP20220738T1
(hr)
|
2014-08-11 |
2022-08-19 |
Acerta Pharma B.V. |
Terapijske kombinacije inhibitora btk, inhibitora pd-1 i/ili inhibitora pd-l1
|
|
HUE046661T2
(hu)
|
2014-08-15 |
2020-03-30 |
Merck Patent Gmbh |
SIRP-alfa immunglobulin fúziós proteinek
|
|
CN112587672A
(zh)
|
2014-09-01 |
2021-04-02 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-pd-l1结合物
|
|
JP6681905B2
(ja)
|
2014-09-13 |
2020-04-15 |
ノバルティス アーゲー |
Alk阻害剤の併用療法
|
|
CN107074952B
(zh)
*
|
2014-09-30 |
2021-04-09 |
英特维特国际股份有限公司 |
结合犬pd-l1的pd-l1抗体
|
|
KR101619862B1
(ko)
*
|
2014-09-30 |
2016-05-12 |
주식회사 녹십자 |
간접효소면역측정법을 이용하는 인간 Fc 포함 단백질의 역가 측정키트 및 이를 이용한 Fc 포함 단백질의 역가 측정방법
|
|
KR20170066546A
(ko)
|
2014-10-03 |
2017-06-14 |
노파르티스 아게 |
조합 요법
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
EP4029508A1
(en)
|
2014-10-10 |
2022-07-20 |
Idera Pharmaceuticals, Inc. |
Treatment of cancer using tlr9 agonists and checkpoint inhibitors
|
|
EA201790834A1
(ru)
|
2014-10-14 |
2018-01-31 |
Новартис Аг |
Молекулы антител к pd-l1 и их применение
|
|
HUE054526T2
(hu)
|
2014-10-29 |
2021-09-28 |
Bicyclerd Ltd |
MT1-MMP-ra specifikus biciklusos peptid ligandumok
|
|
AR102537A1
(es)
|
2014-11-05 |
2017-03-08 |
Flexus Biosciences Inc |
Agentes inmunomoduladores
|
|
UY36390A
(es)
|
2014-11-05 |
2016-06-01 |
Flexus Biosciences Inc |
Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen
|
|
MX2017005462A
(es)
|
2014-11-05 |
2017-07-28 |
Flexus Biosciences Inc |
Agentes inmunorreguladores.
|
|
MX2017006408A
(es)
|
2014-11-17 |
2018-03-23 |
Adicet Bio Inc |
Linfocitos t gamma delta modificados geneticamente.
|
|
JP2017537617A
(ja)
|
2014-12-05 |
2017-12-21 |
アビッドバイオティクス コーポレイション |
抗体の挿入可能な可変フラグメントおよびnkg2dリガンドの改変α1−α2ドメイン
|
|
HUE067123T2
(hu)
|
2014-12-09 |
2024-10-28 |
Regeneron Pharma |
Humanizált differenciációs klaszter 274 génnel rendelkezõ nem humán állatok
|
|
EA032138B1
(ru)
|
2014-12-16 |
2019-04-30 |
Новартис Аг |
СОЕДИНЕНИЯ ИЗОКСАЗОЛГИДРОКСАМИНОВОЙ КИСЛОТЫ В КАЧЕСТВЕ ИНГИБИТОРОВ LpxC
|
|
WO2016100882A1
(en)
|
2014-12-19 |
2016-06-23 |
Novartis Ag |
Combination therapies
|
|
CN105777906B
(zh)
*
|
2014-12-19 |
2019-04-23 |
苏州丁孚靶点生物技术有限公司 |
抗pd-l1全人抗体及其应用
|
|
TW201630907A
(zh)
|
2014-12-22 |
2016-09-01 |
必治妥美雅史谷比公司 |
TGFβR拮抗劑
|
|
JP6180663B2
(ja)
|
2014-12-23 |
2017-08-16 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
Tigitに対する抗体
|
|
GB201500319D0
(en)
*
|
2015-01-09 |
2015-02-25 |
Agency Science Tech & Res |
Anti-PD-L1 antibodies
|
|
CN107428818A
(zh)
|
2015-01-29 |
2017-12-01 |
密西根州立大学校董会 |
隐藏多肽及其用途
|
|
EP3254110B1
(en)
|
2015-02-03 |
2020-03-18 |
Ventana Medical Systems, Inc. |
Histochemical assay for evaluating expression of programmed death ligand 1 (pd-l1)
|
|
WO2016127052A1
(en)
|
2015-02-05 |
2016-08-11 |
Bristol-Myers Squibb Company |
Cxcl11 and smica as predictive biomarkers for efficacy of anti-ctla4 immunotherapy
|
|
WO2016128912A1
(en)
|
2015-02-12 |
2016-08-18 |
Acerta Pharma B.V. |
Therapeutic combinations of a btk inhibitor, a pi3k inhibitor, a jak-2 inhibitor, a pd-1 inhibitor, and/or a pd-l1 inhibitor
|
|
US11318163B2
(en)
|
2015-02-18 |
2022-05-03 |
Enlivex Therapeutics Ltd |
Combination immune therapy and cytokine control therapy for cancer treatment
|
|
US11596652B2
(en)
|
2015-02-18 |
2023-03-07 |
Enlivex Therapeutics R&D Ltd |
Early apoptotic cells for use in treating sepsis
|
|
JP6858128B2
(ja)
|
2015-02-18 |
2021-04-14 |
エンリヴェックス セラピューティクス リミテッド |
癌治療のための免疫療法とサイトカイン制御療法との組み合わせ
|
|
US11497767B2
(en)
|
2015-02-18 |
2022-11-15 |
Enlivex Therapeutics R&D Ltd |
Combination immune therapy and cytokine control therapy for cancer treatment
|
|
US11304976B2
(en)
|
2015-02-18 |
2022-04-19 |
Enlivex Therapeutics Ltd |
Combination immune therapy and cytokine control therapy for cancer treatment
|
|
US11000548B2
(en)
|
2015-02-18 |
2021-05-11 |
Enlivex Therapeutics Ltd |
Combination immune therapy and cytokine control therapy for cancer treatment
|
|
BR112017018234A2
(pt)
|
2015-02-26 |
2018-04-17 |
Merck Patent Gmbh |
inibidores de pd-1 / pd-l1 para o tratamento de câncer
|
|
RU2742312C1
(ru)
*
|
2015-02-26 |
2021-02-04 |
Мерк Патент Гмбх |
Ингибиторы pd-1 / pd-l1 для лечения рака
|
|
AU2016226468B2
(en)
|
2015-03-02 |
2020-10-22 |
Bristol-Myers Squibb Company |
TGF-beta inhibitors
|
|
US20180044429A1
(en)
|
2015-03-09 |
2018-02-15 |
Celldex Therapeutics, Inc. |
Cd27 agonists
|
|
EA035817B1
(ru)
|
2015-03-10 |
2020-08-14 |
Адуро Байотек, Инк. |
Композиции и способы для активации сигналинга, зависимого от "гена стимулятора интерферона"
|
|
EP3067062A1
(en)
*
|
2015-03-13 |
2016-09-14 |
Ipsen Pharma S.A.S. |
Combination of tasquinimod or a pharmaceutically acceptable salt thereof and a pd1 and/or pdl1 inhibitor, for use as a medicament
|
|
IL292449B2
(en)
|
2015-03-13 |
2024-02-01 |
Cytomx Therapeutics Inc |
Nucleic acids encoding anti-pdl1 antibodie and methods of producing same
|
|
JP6815329B2
(ja)
|
2015-03-23 |
2021-01-20 |
バイエル ファーマ アクチエンゲゼルシャフト |
抗ceacam6抗体およびその使用
|
|
US11933786B2
(en)
|
2015-03-30 |
2024-03-19 |
Stcube, Inc. |
Antibodies specific to glycosylated PD-L1 and methods of use thereof
|
|
US10836827B2
(en)
|
2015-03-30 |
2020-11-17 |
Stcube, Inc. |
Antibodies specific to glycosylated PD-L1 and methods of use thereof
|
|
MX2017012729A
(es)
|
2015-04-03 |
2017-11-15 |
Bristol Myers Squibb Co |
Inhibidores de indolamina 2,3-dioxigenasa (ido) para el tratamiento de cancer.
|
|
DK3281641T3
(da)
|
2015-04-07 |
2021-01-18 |
Cytlimic Inc |
Adjuvans til cancervacciner
|
|
WO2016162505A1
(en)
|
2015-04-08 |
2016-10-13 |
F-Star Biotechnology Limited |
Her2 binding agent therapies
|
|
DK3283107T3
(da)
|
2015-04-17 |
2020-08-31 |
Bristol Myers Squibb Co |
Sammensætninger omfattende en kombination af ipilimumab og nivolumab
|
|
EP3283508B1
(en)
|
2015-04-17 |
2021-03-17 |
Alpine Immune Sciences, Inc. |
Immunomodulatory proteins with tunable affinities
|
|
US10857181B2
(en)
|
2015-04-21 |
2020-12-08 |
Enlivex Therapeutics Ltd |
Therapeutic pooled blood apoptotic cell preparations and uses thereof
|
|
EP3736287A1
(en)
|
2015-05-11 |
2020-11-11 |
The Johns Hopkins University |
Autoimmune antibodies for use in inhibiting cancer cell growth
|
|
WO2016183114A1
(en)
|
2015-05-11 |
2016-11-17 |
Bristol-Myers Squibb Company |
Tricyclic compounds as anticancer agents
|
|
US9725449B2
(en)
|
2015-05-12 |
2017-08-08 |
Bristol-Myers Squibb Company |
Tricyclic compounds as anticancer agents
|
|
EP3307740B1
(en)
|
2015-05-12 |
2019-12-18 |
Bristol-Myers Squibb Company |
5h-pyrido[3,2-b]indole compounds as anticancer agents
|
|
CA2929850A1
(en)
|
2015-05-14 |
2016-11-14 |
Pfizer Inc. |
Combination therapies comprising a pyrrolidine-2,5-dione ido1 inhibitor
|
|
PT3298021T
(pt)
|
2015-05-18 |
2019-08-05 |
Tolero Pharmaceuticals Inc |
Pró-fármacos de alvocidib possuindo biodisponibilidade aumentada
|
|
ES2904252T3
(es)
|
2015-05-21 |
2022-04-04 |
Chemocentryx Inc |
Moduladores de CCR2
|
|
SG10202002131PA
(en)
|
2015-05-21 |
2020-05-28 |
Harpoon Therapeutics Inc |
Trispecific binding proteins and methods of use
|
|
TWI715587B
(zh)
*
|
2015-05-28 |
2021-01-11 |
美商安可美德藥物股份有限公司 |
Tigit結合劑和彼之用途
|
|
US20180155429A1
(en)
|
2015-05-28 |
2018-06-07 |
Bristol-Myers Squibb Company |
Treatment of pd-l1 positive lung cancer using an anti-pd-1 antibody
|
|
HRP20201031T1
(hr)
|
2015-05-29 |
2020-10-16 |
Agenus Inc. |
Anti-ctla-4 protutijela i postupci njihove upotrebe
|
|
US11078278B2
(en)
|
2015-05-29 |
2021-08-03 |
Bristol-Myers Squibb Company |
Treatment of renal cell carcinoma
|
|
RS63897B1
(sr)
|
2015-05-29 |
2023-02-28 |
Bristol Myers Squibb Co |
Antitela protiv ox40 i njihova primena
|
|
CN115554399A
(zh)
|
2015-05-31 |
2023-01-03 |
源生公司 |
用于免疫疗法的组合组合物
|
|
US9782410B2
(en)
*
|
2015-06-09 |
2017-10-10 |
Rexahn Pharmaceuticals, Inc. |
Fluorocyclopentenylcytosine methods of use
|
|
CN106243225B
(zh)
*
|
2015-06-11 |
2021-01-19 |
智翔(上海)医药科技有限公司 |
新型抗-pd-l1抗体
|
|
WO2016197367A1
(en)
|
2015-06-11 |
2016-12-15 |
Wuxi Biologics (Shanghai) Co. Ltd. |
Novel anti-pd-l1 antibodies
|
|
US20180179282A1
(en)
|
2015-06-12 |
2018-06-28 |
Bristol-Myers Squibb Company |
Treatment of cancer by combined blockade of the pd-1 and cxcr4 signaling pathways
|
|
RU2766890C2
(ru)
|
2015-06-16 |
2022-03-16 |
Мерк Патент Гмбх |
Комбинированные способы лечения антагонистами pd-l1
|
|
EP3310815A1
(en)
|
2015-06-17 |
2018-04-25 |
F. Hoffmann-La Roche AG |
Methods of treating locally advanced or metastatic breast cancers using pd-1 axis binding antagonists and taxanes
|
|
MY193078A
(en)
|
2015-06-24 |
2022-09-26 |
Hoffmann La Roche |
Anti-transferrin receptor antibodies with tailored affinity
|
|
BR112017027653A2
(pt)
|
2015-06-29 |
2018-08-28 |
Ose Immunotherapeutics |
método para induzir a resposta de memória t precoce com vacina anti-tumoral de peptídeos curtos
|
|
CA2990015A1
(en)
|
2015-06-29 |
2017-01-05 |
The Rockefeller University |
Antibodies to cd40 with enhanced agonist activity
|
|
RS61532B1
(sr)
|
2015-07-14 |
2021-04-29 |
Bristol Myers Squibb Co |
Postupak lečenja kancera primenom inhibitora imunološke kontrolne tačke; antitelo koje se vezuje za receptor programirane smrti-1 (pd-1) ili ligand programirane smrti-1 (pd-l1)
|
|
BR112018000917A2
(pt)
|
2015-07-16 |
2018-09-11 |
Bioxcel Therapeutics Inc |
abordagem inovadora para o tratamento de câncer através da imunomodulação
|
|
US10399987B2
(en)
|
2015-07-28 |
2019-09-03 |
Bristol-Myer Squibb Company |
TGF beta receptor antagonists
|
|
EP3316902A1
(en)
|
2015-07-29 |
2018-05-09 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
|
US20180222982A1
(en)
|
2015-07-29 |
2018-08-09 |
Novartis Ag |
Combination therapies comprising antibody molecules to pd-1
|
|
ES2878188T3
(es)
|
2015-07-29 |
2021-11-18 |
Novartis Ag |
Terapias de combinación que comprenden moléculas de anticuerpos contra LAG-3
|
|
CN106397592A
(zh)
*
|
2015-07-31 |
2017-02-15 |
苏州康宁杰瑞生物科技有限公司 |
针对程序性死亡配体(pd-l1)的单域抗体及其衍生蛋白
|
|
WO2017020291A1
(en)
*
|
2015-08-06 |
2017-02-09 |
Wuxi Biologics (Shanghai) Co. Ltd. |
Novel anti-pd-l1 antibodies
|
|
AR105654A1
(es)
|
2015-08-24 |
2017-10-25 |
Lilly Co Eli |
Anticuerpos pd-l1 (ligando 1 de muerte celular programada)
|
|
KR20180042370A
(ko)
|
2015-08-25 |
2018-04-25 |
브리스톨-마이어스 스큅 컴퍼니 |
Tgf 베타 수용체 길항제
|
|
CA2994184A1
(en)
*
|
2015-09-04 |
2017-03-09 |
Rexahn Pharmaceuticals, Inc. |
Quinoxalinyl-piperazinamide methods of use
|
|
CN114230571B
(zh)
|
2015-09-14 |
2025-07-08 |
无限药品股份有限公司 |
异喹啉酮的固体形式、其制备方法、包含其的组合物及其使用方法
|
|
MA44909A
(fr)
|
2015-09-15 |
2018-07-25 |
Acerta Pharma Bv |
Association thérapeutique d'un inhibiteur du cd19 et d'un inhibiteur de la btk
|
|
CN106540255A
(zh)
*
|
2015-09-18 |
2017-03-29 |
聊城市奥润生物医药科技有限公司 |
环二核苷酸cGAMP联合贝伐珠单抗在抗肿瘤中的应用
|
|
EP3356551B1
(en)
|
2015-09-29 |
2020-09-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for determining the metabolic status of b-lymphomas
|
|
US20180282415A1
(en)
|
2015-09-30 |
2018-10-04 |
Merck Patent Gmbh |
Combination of a PD-1 Axis Binding Antagonist and an ALK Inhibitor for Treating ALK-Negative Cancer
|
|
AR106189A1
(es)
|
2015-10-02 |
2017-12-20 |
Hoffmann La Roche |
ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO
|
|
CN108137697A
(zh)
|
2015-10-02 |
2018-06-08 |
豪夫迈·罗氏有限公司 |
双特异性抗人cd20/人转铁蛋白受体抗体及使用方法
|
|
CN106565836B
(zh)
*
|
2015-10-10 |
2020-08-18 |
中国科学院广州生物医药与健康研究院 |
高亲和力的可溶性pdl-1分子
|
|
ES2994611T3
(en)
|
2015-10-19 |
2025-01-27 |
Cg Oncology Inc |
Methods of treating solid or lymphatic tumors by combination therapy
|
|
US10149887B2
(en)
|
2015-10-23 |
2018-12-11 |
Canbas Co., Ltd. |
Peptides and peptidomimetics in combination with t cell activating and/or checkpoint inhibiting agents for cancer treatment
|
|
SI3370733T1
(sl)
|
2015-11-02 |
2021-11-30 |
Board Of Regents The University Of Texas System |
Postopek za aktivacijo CD40 in blokada imunske nadzorne točke
|
|
CA3004804A1
(en)
*
|
2015-11-17 |
2017-05-26 |
Jiangsu Hengrui Medicine Co., Ltd. |
Pd-l1 antibody, antigen-binding fragment thereof and medical application thereof
|
|
US11072657B2
(en)
|
2015-11-18 |
2021-07-27 |
Bristol-Myers Squibb Company |
Treatment of lung cancer using a combination of an anti-PD-1 antibody and an anti-CTLA-4 antibody
|
|
BR112018010172A2
(pt)
|
2015-11-19 |
2018-11-21 |
Bristol Myers Squibb Co |
anticorpos contra receptor de fator de necrose de tumor induzido por glicocorticoide (gitr) e usos dos mesmos
|
|
EP3383412A4
(en)
|
2015-12-02 |
2019-06-05 |
Stcube, Inc. |
SPECIFIC ANTIBODIES TO GLYCOSED PD-1 AND METHOD OF USE THEREOF
|
|
CR20180286A
(es)
|
2015-12-03 |
2018-07-16 |
Glaxosmithkline Ip Dev Ltd |
Dinucleotidos de purina cíclicos como moduladores de sting
|
|
BR112018010211A2
(pt)
*
|
2015-12-07 |
2019-02-05 |
Merck Patent Gmbh |
formulação farmacêutica aquosa compreendendo anticorpo anti-pd-l1 avelumab
|
|
WO2017098421A1
(en)
|
2015-12-08 |
2017-06-15 |
Glaxosmithkline Intellectual Property Development Limited |
Benzothiadiazine compounds
|
|
KR102738306B1
(ko)
|
2015-12-15 |
2024-12-03 |
브리스톨-마이어스 스큅 컴퍼니 |
Cxcr4 수용체 길항제
|
|
GB201522311D0
(en)
|
2015-12-17 |
2016-02-03 |
Photocure Asa |
Use
|
|
WO2017106656A1
(en)
|
2015-12-17 |
2017-06-22 |
Novartis Ag |
Antibody molecules to pd-1 and uses thereof
|
|
EP3390454A4
(en)
*
|
2015-12-17 |
2019-08-28 |
University of Maryland, Baltimore County |
RECOMBINANT BISPEZIFIC POLYPEPTIDE FOR THE COORDINATED ACTIVATION OF TUMOR REACTIVE T CELLS AND FOR THE NEUTRALIZATION OF IMMUNOSUPPRESSION
|
|
GB201522309D0
(en)
|
2015-12-17 |
2016-02-03 |
Photocure Asa |
Use
|
|
JP2019506844A
(ja)
|
2015-12-18 |
2019-03-14 |
ノバルティス アーゲー |
CD32bを標的とする抗体およびその使用方法
|
|
EP4643874A2
(en)
|
2015-12-22 |
2025-11-05 |
Novartis AG |
Mesothelin chimeric antigen receptor (car) and antibody against pd-l1 inhibitor for combined use in anticancer therapy
|
|
PT3394103T
(pt)
|
2015-12-22 |
2023-09-04 |
Regeneron Pharma |
Combinação de anticorpos anti-pd-1 e anticorpos biespecíj'icos anti-cd20/anti-cd3 para tratar cancro
|
|
HRP20220525T1
(hr)
|
2015-12-23 |
2022-05-27 |
Modernatx, Inc. |
Postupci uporabe polinukleotida koji kodiraju ligand ox40
|
|
CN105461808B
(zh)
*
|
2015-12-24 |
2019-03-19 |
长春金赛药业股份有限公司 |
单克隆抗体及其应用
|
|
EP3400443B1
(en)
|
2016-01-04 |
2020-09-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of pd-1 and tim-3 as a measure for cd8+ cells in predicting and treating renal cell carcinoma
|
|
CN106939047B
(zh)
*
|
2016-01-04 |
2021-08-31 |
江苏怀瑜药业有限公司 |
一种pd-l1抗体及其制备方法
|
|
US20190008869A1
(en)
|
2016-01-13 |
2019-01-10 |
Acerta Pharma B.V. |
Therapeutic Combinations of an Antifolate and a BTK Inhibitor
|
|
EA201891732A1
(ru)
*
|
2016-02-02 |
2019-02-28 |
Кадмон Корпорейшн, Ллк |
Биспецифичные связывающие белки для pd-l1 и kdr
|
|
US11730761B2
(en)
|
2016-02-18 |
2023-08-22 |
Enlivex Therapeutics Rdo Ltd |
Combination immune therapy and cytokine control therapy for cancer treatment
|
|
US9845325B2
(en)
|
2016-02-19 |
2017-12-19 |
Novartis Ag |
Tetracyclic pyridone compounds as antivirals
|
|
EP3420000A1
(en)
|
2016-02-25 |
2019-01-02 |
Cell Medica Switzerland AG |
Modified cells for immunotherapy
|
|
US10465014B2
(en)
*
|
2016-03-04 |
2019-11-05 |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. |
PDL-1 antibody, pharmaceutical composition thereof, and uses thereof
|
|
JP7208492B2
(ja)
|
2016-03-10 |
2023-01-19 |
シージー オンコロジー, インコーポレイテッド |
併用療法によって固形腫瘍又はリンパ系腫瘍を処置する方法
|
|
WO2017153952A1
(en)
|
2016-03-10 |
2017-09-14 |
Glaxosmithkline Intellectual Property Development Limited |
5-sulfamoyl-2-hydroxybenzamide derivatives
|
|
CN109153719B
(zh)
|
2016-03-15 |
2022-12-30 |
中外制药株式会社 |
使用pd-1轴结合拮抗剂和抗gpc3抗体治疗癌症的方法
|
|
BR112018068461A2
(pt)
|
2016-03-15 |
2019-01-22 |
Mersana Therapeutics Inc |
conjugado, composição farmacêutica, métodos para preparação de um conjugado e para alívio de um sintoma de um câncer.
|
|
CN107216389B
(zh)
|
2016-03-18 |
2022-03-29 |
和迈生物科技有限公司 |
抗pd-l1纳米抗体及其编码序列和用途
|
|
RU2744959C2
(ru)
*
|
2016-03-23 |
2021-03-17 |
Мэбспейс Байосайнсиз (Сучжоу) Ко., Лтд |
Новые анти-pd-l1 антитела
|
|
PT3433257T
(pt)
|
2016-03-24 |
2023-11-29 |
Novartis Ag |
Análogos nucleosídeos de alquinil como inibidores do rinovírus humano
|
|
WO2017172518A1
(en)
|
2016-03-29 |
2017-10-05 |
Stcube, Inc. |
Dual function antibodies specific to glycosylated pd-l1 and methods of use thereof
|
|
EP3436475A1
(en)
|
2016-03-29 |
2019-02-06 |
STCube & Co., Inc. |
Methods for selecting antibodies that specifically bind glycosylated immune checkpoint proteins
|
|
EP3225253A1
(en)
|
2016-04-01 |
2017-10-04 |
Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts |
Cancer therapy with an oncolytic virus combined with a checkpoint inhibitor
|
|
US11209441B2
(en)
|
2016-04-05 |
2021-12-28 |
Bristol-Myers Squibb Company |
Cytokine profiling analysis
|
|
PL3439653T3
(pl)
|
2016-04-07 |
2021-07-05 |
Chemocentryx, Inc. |
Zmniejszenie obciążenia guzem przez podawanie antagonistów ccr1 w skojarzeniu z inhibitorami pd-1 lub inhibitorami pd-l1
|
|
CN109789195A
(zh)
|
2016-04-13 |
2019-05-21 |
维维雅生物技术公司 |
离体bite激活的t细胞
|
|
US11353459B2
(en)
*
|
2016-04-14 |
2022-06-07 |
Creatv Microtech, Inc. |
Methods of using PD-L1 expression in treatment decisions for cancer therapy
|
|
SMT202400438T1
(it)
|
2016-04-14 |
2024-11-15 |
Ose Immunotherapeutics |
Nuovi anticorpi anti-sirpa e loro applicazioni terapeutiche
|
|
US10865244B2
(en)
|
2016-04-18 |
2020-12-15 |
Celldex Therapeutics, Inc. |
Nucleic acids encoding agonistic antibodies that bind CD40
|
|
CN105695406A
(zh)
*
|
2016-04-27 |
2016-06-22 |
天津普瑞赛尔生物科技有限公司 |
制备具有高效肿瘤杀伤性dc-cik免疫细胞的方法及制得的dc-cik免疫细胞
|
|
EP3452451A4
(en)
|
2016-05-04 |
2019-11-13 |
Bristol-Myers Squibb Company |
INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS AND METHODS OF USE
|
|
CN109414420A
(zh)
|
2016-05-04 |
2019-03-01 |
百时美施贵宝公司 |
吲哚胺2,3-双加氧酶的抑制剂及其使用方法
|
|
JP2019516681A
(ja)
|
2016-05-04 |
2019-06-20 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
インドールアミン2,3−ジオキシゲナーゼ阻害剤およびその使用方法
|
|
CN109414421A
(zh)
|
2016-05-04 |
2019-03-01 |
百时美施贵宝公司 |
吲哚胺2,3-双加氧酶的抑制剂及其使用方法
|
|
JP2019522627A
(ja)
|
2016-05-04 |
2019-08-15 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
インドールアミン2,3−ジオキシゲナーゼ阻害剤およびその使用方法
|
|
MX2018013519A
(es)
|
2016-05-05 |
2019-03-14 |
Glaxosmithkline Ip No 2 Ltd |
Inhibidores del potenciador del homologo zeste 2.
|
|
PT3455257T
(pt)
*
|
2016-05-09 |
2021-12-06 |
Igm Biosciences Inc |
Anticorpos anti-pd-l1
|
|
WO2017197347A1
(en)
|
2016-05-12 |
2017-11-16 |
Adicet Bio, Inc. |
METHODS FOR SELECTIVE EXPANSION OF γδ T-CELL POPULATIONS AND COMPOSITIONS THEREOF
|
|
TWI755395B
(zh)
|
2016-05-13 |
2022-02-21 |
美商再生元醫藥公司 |
抗-pd-1抗體與輻射治療癌症之組合
|
|
PT3458474T
(pt)
|
2016-05-18 |
2022-11-08 |
Modernatx Inc |
Combinações de arnm que codificam polipéptidos de modulação imunitária e as suas utilizações
|
|
CN109195621A
(zh)
|
2016-05-18 |
2019-01-11 |
莫得纳特斯公司 |
编码白细胞介素12(il12)的多核苷酸及其用途
|
|
BR112018073606A2
(pt)
|
2016-05-18 |
2019-02-26 |
Cue Biopharma, Inc. |
polipeptídeos multiméricos moduladores de células t e métodos de uso dos mesmos
|
|
WO2017201432A2
(en)
|
2016-05-19 |
2017-11-23 |
Jounaidi Youssef |
Tethered interleukin-2 to its receptor il-2rbeta, a platform to enhance natural killer and regulatory t cell activity
|
|
JP7194022B2
(ja)
|
2016-05-20 |
2022-12-21 |
イーライ リリー アンド カンパニー |
Notch阻害剤とPD-1またはPD-L1阻害剤との併用療法
|
|
US11623958B2
(en)
|
2016-05-20 |
2023-04-11 |
Harpoon Therapeutics, Inc. |
Single chain variable fragment CD3 binding proteins
|
|
WO2017202744A1
(en)
|
2016-05-26 |
2017-11-30 |
Merck Patent Gmbh |
Pd-1 / pd-l1 inhibitors for cancer treatment
|
|
CA3024508A1
(en)
|
2016-05-27 |
2017-11-30 |
Agenus Inc. |
Anti-tim-3 antibodies and methods of use thereof
|
|
HRP20230864T1
(hr)
|
2016-06-02 |
2023-11-10 |
Bristol-Myers Squibb Company |
Pd-1 blokada nivolumabom kod refraktornog hodgkinovog limfoma
|
|
KR20230119265A
(ko)
|
2016-06-02 |
2023-08-16 |
브리스톨-마이어스 스큅 컴퍼니 |
림프종 치료에서의 항-cd30 항체와 조합된 항-pd-1항체의 용도
|
|
KR20190015408A
(ko)
|
2016-06-03 |
2019-02-13 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법에 사용하기 위한 항-pd-1 항체
|
|
WO2017210637A1
(en)
|
2016-06-03 |
2017-12-07 |
Bristol-Myers Squibb Company |
Use of anti-pd-1 antibody in the treatment of patients with colorectal cancer
|
|
KR20190015407A
(ko)
|
2016-06-03 |
2019-02-13 |
브리스톨-마이어스 스큅 컴퍼니 |
재발성 소세포 폐암의 치료 방법에 사용하기 위한 항-pd-1 항체
|
|
ES2913929T3
(es)
|
2016-06-08 |
2022-06-06 |
Glaxosmithkline Ip Dev Ltd |
Compuestos químicos como inhibidores de la ruta de ATF4
|
|
US11472856B2
(en)
|
2016-06-13 |
2022-10-18 |
Torque Therapeutics, Inc. |
Methods and compositions for promoting immune cell function
|
|
US10077308B2
(en)
|
2016-06-13 |
2018-09-18 |
Askgene Pharma Inc. |
PD-L1 specific monoclonal antibodies for disease treatment and diagnosis
|
|
AU2017284632B2
(en)
|
2016-06-13 |
2020-05-14 |
I-Mab Biopharma Co., Ltd. |
Anti-PD-L1 antibodies and uses thereof
|
|
MA45250B1
(fr)
|
2016-06-14 |
2020-09-30 |
Novartis Ag |
Forme crystalline de (r)-4-(5-(cyclopropyléthynyl)isoxazol-3-yl)-n-hydroxy-2-méthyl-2-(méthylsulfonyl)butanamide en tant qu'agent antibacteriel
|
|
WO2017216685A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
Pentacyclic pyridone compounds as antivirals
|
|
WO2017216686A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
8,9-fused 2-oxo-6,7-dihydropyrido-isoquinoline compounds as antivirals
|
|
CN116903741A
(zh)
*
|
2016-06-20 |
2023-10-20 |
科马布有限公司 |
特异性结合于pd-l1的抗体或其抗原结合片段及其用途
|
|
US9567399B1
(en)
|
2016-06-20 |
2017-02-14 |
Kymab Limited |
Antibodies and immunocytokines
|
|
RU2018142573A
(ru)
|
2016-06-20 |
2020-07-21 |
Ф-Стар Бета Лимитед |
Партнеры по связыванию lag-3
|
|
WO2018029474A2
(en)
|
2016-08-09 |
2018-02-15 |
Kymab Limited |
Anti-icos antibodies
|
|
CA3028718A1
(en)
|
2016-06-24 |
2017-12-28 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
|
WO2017222556A2
(en)
|
2016-06-24 |
2017-12-28 |
Avidbiotics Corp. |
Insertable variable fragments of antibodies and modified a1-a2 domains of nkg2d ligands
|
|
CA3027204A1
(en)
*
|
2016-06-29 |
2018-01-04 |
Checkpoint Therapeutics, Inc. |
Pd-l1-specific antibodies and methods of using the same
|
|
RU2021127872A
(ru)
|
2016-06-30 |
2021-11-09 |
Онкорус, Инк. |
Доставка терапевтических полипептидов посредством псевдотипированных онколитических вирусов
|
|
AU2017293423B2
(en)
|
2016-07-05 |
2023-05-25 |
Beone Medicines I Gmbh |
Combination of a PD-1 antagonist and a RAF inhibitor for treating cancer
|
|
WO2018009466A1
(en)
|
2016-07-05 |
2018-01-11 |
Aduro Biotech, Inc. |
Locked nucleic acid cyclic dinucleotide compounds and uses thereof
|
|
EP4512829A3
(en)
|
2016-07-14 |
2025-06-11 |
Bristol-Myers Squibb Company |
Antibodies against tim3 and uses thereof
|
|
GB201612520D0
(en)
|
2016-07-19 |
2016-08-31 |
F-Star Beta Ltd |
Binding molecules
|
|
AU2017300123A1
(en)
|
2016-07-20 |
2019-01-31 |
Glaxosmithkline Intellectual Property Development Limited |
Isoquinoline derivatives as PERK inhibitors
|
|
JP2019528251A
(ja)
|
2016-07-20 |
2019-10-10 |
エスティーキューブ,インコーポレイテッド |
グリコシル化pd−l1に結合する抗体の組合せを使用するがんの処置および治療の方法
|
|
WO2018017633A1
(en)
|
2016-07-21 |
2018-01-25 |
Bristol-Myers Squibb Company |
TGF Beta RECEPTOR ANTAGONISTS
|
|
JP2019527236A
(ja)
|
2016-08-01 |
2019-09-26 |
モレキュラー テンプレーツ,インコーポレイティド |
癌を治療するための免疫調節剤と組み合わせた低酸素活性化型プロドラッグの投与
|
|
AU2017305366B2
(en)
*
|
2016-08-04 |
2019-06-20 |
Innovent Biologics (Suzhou) Co., Ltd |
Anti-PD-L1 nanobody and use thereof
|
|
EP3496707A4
(en)
*
|
2016-08-09 |
2020-03-25 |
Angimmune, LLC |
Treatment of cancer using a combination of immunomodulation and check point inhibitors
|
|
CN117736325A
(zh)
|
2016-08-09 |
2024-03-22 |
科马布有限公司 |
分离抗体及其应用
|
|
BR112019001818A2
(pt)
|
2016-08-12 |
2019-05-07 |
Merck Patent Gmbh |
terapia combinada para câncer
|
|
AU2017313085B2
(en)
|
2016-08-19 |
2024-06-20 |
Beone Medicines I Gmbh |
Use of a combination comprising a Btk inhibitor for treating cancers
|
|
JP7138094B2
(ja)
|
2016-08-25 |
2022-09-15 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
マクロファージ活性化剤と組み合わせた抗csf-1r抗体の間欠投与
|
|
JP2019528300A
(ja)
|
2016-08-26 |
2019-10-10 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
インドールアミン2,3−ジオキシゲナーゼの阻害剤およびその使用方法
|
|
CN106248955A
(zh)
*
|
2016-09-03 |
2016-12-21 |
长春工业大学 |
一种检测人源化pd‑l1抗体的试剂盒
|
|
WO2018047109A1
(en)
|
2016-09-09 |
2018-03-15 |
Novartis Ag |
Polycyclic pyridone compounds as antivirals
|
|
WO2018048975A1
(en)
|
2016-09-09 |
2018-03-15 |
Bristol-Myers Squibb Company |
Use of an anti-pd-1 antibody in combination with an anti-mesothelin antibody in cancer treatment
|
|
JP2019526595A
(ja)
|
2016-09-09 |
2019-09-19 |
ティージー セラピューティクス,インコーポレイテッド |
血液癌を治療するための抗cd20抗体、pi3キナーゼ−デルタ阻害剤および抗pd−1抗体または抗pd−l1抗体の組み合わせ
|
|
US11673971B2
(en)
|
2016-09-23 |
2023-06-13 |
Marengo Therapeutics, Inc. |
Multispecific antibody molecules comprising lambda and kappa light chains
|
|
JOP20190061A1
(ar)
|
2016-09-28 |
2019-03-26 |
Novartis Ag |
مثبطات بيتا-لاكتاماز
|
|
EP4541423A3
(en)
|
2016-10-06 |
2025-06-25 |
Pfizer Inc. |
Dosing regimen of avelumab for the treatment of cancer
|
|
WO2018071500A1
(en)
|
2016-10-11 |
2018-04-19 |
Agenus Inc. |
Anti-lag-3 antibodies and methods of use thereof
|
|
RU2759728C2
(ru)
|
2016-10-11 |
2021-11-17 |
Ситлимик Инк. |
Лекарственное средство
|
|
BR112018013653B1
(pt)
|
2016-10-15 |
2020-12-15 |
Innovent Biologics (Suzhou) Co., Ltd |
Anticorpos anti-pd-1, processo para produção do mesmo e uso dos anticorpos
|
|
TW201819380A
(zh)
|
2016-10-18 |
2018-06-01 |
瑞士商諾華公司 |
作為抗病毒劑之稠合四環吡啶酮化合物
|
|
CN110099925A
(zh)
|
2016-10-28 |
2019-08-06 |
百时美施贵宝公司 |
使用抗pd-1抗体治疗尿道上皮癌的方法
|
|
KR102543323B1
(ko)
*
|
2016-10-30 |
2023-06-14 |
상하이 헨리우스 바이오테크, 인크. |
항-pd-l1 항체 및 변이체
|
|
TWI788307B
(zh)
|
2016-10-31 |
2023-01-01 |
美商艾歐凡斯生物治療公司 |
用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
|
|
WO2018083248A1
(en)
|
2016-11-03 |
2018-05-11 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses & methods
|
|
AU2017355446A1
(en)
|
2016-11-03 |
2019-05-02 |
Bristol-Myers Squibb Company |
Activatable anti-CTLA-4 antibodies and uses thereof
|
|
WO2018085935A1
(en)
*
|
2016-11-09 |
2018-05-17 |
Engene, Inc. |
Intestinal expression of programmed death ligand 1
|
|
US11471515B2
(en)
|
2016-11-09 |
2022-10-18 |
The Brigham And Women's Hospital, Inc. |
Restoration of tumor suppression using MRNA-based delivery system
|
|
US10660909B2
(en)
|
2016-11-17 |
2020-05-26 |
Syntrix Biosystems Inc. |
Method for treating cancer using chemokine antagonists
|
|
CN106496327B
(zh)
*
|
2016-11-18 |
2019-01-15 |
昆山百尔泰生物科技有限公司 |
针对pd-l1胞外段的人源抗体或抗体片段和用途、核苷酸序列和载体
|
|
US11279694B2
(en)
|
2016-11-18 |
2022-03-22 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
|
JOP20190100A1
(ar)
|
2016-11-19 |
2019-05-01 |
Potenza Therapeutics Inc |
بروتينات ربط مولد ضد مضاد لـ gitr وطرق استخدامها
|
|
WO2018098352A2
(en)
|
2016-11-22 |
2018-05-31 |
Jun Oishi |
Targeting kras induced immune checkpoint expression
|
|
US11135307B2
(en)
|
2016-11-23 |
2021-10-05 |
Mersana Therapeutics, Inc. |
Peptide-containing linkers for antibody-drug conjugates
|
|
JP2020500878A
(ja)
|
2016-12-01 |
2020-01-16 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
併用療法
|
|
CN110234342A
(zh)
|
2016-12-01 |
2019-09-13 |
葛兰素史密斯克莱知识产权发展有限公司 |
组合疗法
|
|
KR20190104529A
(ko)
|
2016-12-03 |
2019-09-10 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Car-t 세포의 조절 방법
|
|
US11013802B2
(en)
|
2016-12-07 |
2021-05-25 |
Agenus Inc. |
Anti-CTLA-4 antibodies and methods of use thereof
|
|
AU2017373945B2
(en)
|
2016-12-07 |
2025-01-23 |
Agenus Inc. |
Antibodies and methods of use thereof
|
|
EP3552626A4
(en)
|
2016-12-12 |
2020-06-10 |
Daiichi Sankyo Company, Limited |
ASSOCIATION OF AN ANTIBODY DRUG CONJUGATE AND AN IMMUNE CONTROL POINT INHIBITOR
|
|
WO2018111976A1
(en)
|
2016-12-14 |
2018-06-21 |
Janssen Biotech, Inc. |
Pd-l1 binding fibronectin type iii domains
|
|
US10611823B2
(en)
|
2016-12-14 |
2020-04-07 |
Hanssen Biotech, Inc |
CD137 binding fibronectin type III domains
|
|
BR112019012154A2
(pt)
|
2016-12-14 |
2019-11-12 |
Janssen Biotech Inc |
domínios do tipo iii da fibronectina de ligação a cd8a
|
|
WO2018112360A1
(en)
|
2016-12-16 |
2018-06-21 |
Evelo Biosciences, Inc. |
Combination therapies for treating cancer
|
|
WO2018112364A1
(en)
|
2016-12-16 |
2018-06-21 |
Evelo Biosciences, Inc. |
Combination therapies for treating melanoma
|
|
WO2018119114A1
(en)
|
2016-12-22 |
2018-06-28 |
Cue Biopharma, Inc. |
T-cell modulatory multimeric polypeptides and methods of use thereof
|
|
US11130931B2
(en)
|
2016-12-22 |
2021-09-28 |
The University Of Hong Kong |
Compositions and methods for clearing tissue
|
|
CN110072553B
(zh)
|
2016-12-22 |
2023-09-15 |
豪夫迈·罗氏有限公司 |
在抗pd-l1/pd1治疗失败之后抗csf-1r抗体与抗pd-l1抗体组合对肿瘤的治疗
|
|
EP3559045A4
(en)
*
|
2016-12-23 |
2020-08-19 |
REMD Biotherapeutics, Inc. |
IMMUNOTHERAPY USING ANTIBODIES THAT BIND TO A TIMED DEATH LIGAND 1 (PD-L1)
|
|
WO2018132279A1
(en)
|
2017-01-05 |
2018-07-19 |
Bristol-Myers Squibb Company |
Tgf beta receptor antagonists
|
|
WO2018129497A1
(en)
|
2017-01-09 |
2018-07-12 |
Bioxcel Therapeutics, Inc. |
Predictive and diagnostic methods for prostate cancer
|
|
US11584733B2
(en)
|
2017-01-09 |
2023-02-21 |
Shuttle Pharmaceuticals, Inc. |
Selective histone deacetylase inhibitors for the treatment of human disease
|
|
US11851471B2
(en)
|
2017-01-09 |
2023-12-26 |
Cue Biopharma, Inc. |
T-cell modulatory multimeric polypeptides and methods of use thereof
|
|
EP3565549B1
(en)
|
2017-01-09 |
2022-03-09 |
Shuttle Pharmaceuticals, Inc. |
Selective histone deacetylase inhibitors for the treatment of human disease
|
|
KR20190103226A
(ko)
|
2017-01-13 |
2019-09-04 |
아게누스 인코포레이티드 |
Ny-eso-1에 결합하는 t 세포 수용체 및 이의 사용 방법
|
|
SG11201905812WA
(en)
|
2017-01-20 |
2019-08-27 |
Arcus Biosciences Inc |
Azolopyrimidine for the treatment of cancer-related disorders
|
|
BR112019015069A2
(pt)
|
2017-01-24 |
2020-03-03 |
Pfizer Inc. |
Derivados de caliqueamicina e conjugados de anticorpo-fármaco dos mesmos
|
|
WO2018138110A1
(en)
|
2017-01-25 |
2018-08-02 |
Ose Immunotherapeutics |
Method for manufacturing a stable emulsion for peptide delivery
|
|
US11555038B2
(en)
|
2017-01-25 |
2023-01-17 |
Beigene, Ltd. |
Crystalline forms of (S)-7-(1-(but-2-ynoyl)piperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, preparation, and uses thereof
|
|
EP3573657A4
(en)
*
|
2017-01-29 |
2021-04-14 |
Zequn Tang |
IMMUNE MODULATION METHODS AGAINST FOREIGN ANTIGENS AND / OR AUTOANTIGENS
|
|
WO2018146612A1
(en)
|
2017-02-10 |
2018-08-16 |
Novartis Ag |
1-(4-amino-5-bromo-6-(1 h-pyrazol-1-yl)pyrimidin-2-yl)-1 h-pyrazol-4-ol and use thereof in the treatment of cancer
|
|
WO2018151820A1
(en)
|
2017-02-16 |
2018-08-23 |
Elstar Therapeutics, Inc. |
Multifunctional molecules comprising a trimeric ligand and uses thereof
|
|
TWI674261B
(zh)
|
2017-02-17 |
2019-10-11 |
美商英能腫瘤免疫股份有限公司 |
Nlrp3 調節劑
|
|
CN108456251A
(zh)
|
2017-02-21 |
2018-08-28 |
上海君实生物医药科技股份有限公司 |
抗pd-l1抗体及其应用
|
|
WO2018156888A1
(en)
|
2017-02-24 |
2018-08-30 |
Biothera Pharmaceuticals, Inc. |
Beta glucan immunopharmacodynamics
|
|
CA3053803A1
(en)
|
2017-02-24 |
2018-08-30 |
Macrogenics, Inc. |
Bispecific binding molecules that are capable of binding cd137 and tumor antigens, and uses thereof
|
|
WO2018160538A1
(en)
|
2017-02-28 |
2018-09-07 |
Mersana Therapeutics, Inc. |
Combination therapies of her2-targeted antibody-drug conjugates
|
|
KR20190125363A
(ko)
*
|
2017-03-06 |
2019-11-06 |
메르크 파텐트 게엠베하 |
수성 항-pd-l1 항체 제제
|
|
EP3372615A1
(en)
|
2017-03-06 |
2018-09-12 |
Merck Patent GmbH |
Composition comprising avelumab
|
|
LT3592769T
(lt)
|
2017-03-09 |
2024-08-26 |
Genmab A/S |
Antikūnai, atpažįstantys pd-l1
|
|
EP3596118B1
(en)
|
2017-03-15 |
2024-08-21 |
Cue Biopharma, Inc. |
Combination of multimeric fusion polypeptides and immune checkpoint inhibitor for treating hpv-associated cancer
|
|
US20230220039A1
(en)
*
|
2017-03-16 |
2023-07-13 |
Alpine Immune Sciences, Inc. |
Pd-l1 variant immunomodulatory proteins and uses thereof
|
|
US20210186982A1
(en)
|
2017-03-24 |
2021-06-24 |
Universite Nice Sophia Antipolis |
Methods and compositions for treating melanoma
|
|
JP2020512382A
(ja)
*
|
2017-03-29 |
2020-04-23 |
グリコトープ ゲーエムベーハー |
Pd−l1抗体およびta−muc1抗体
|
|
KR102644408B1
(ko)
|
2017-03-30 |
2024-03-07 |
메르크 파텐트 게엠베하 |
암의 치료를 위한 항-pd-l1 항체 및 dna-pk 억제제의 병용
|
|
WO2018183928A1
(en)
|
2017-03-31 |
2018-10-04 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
US11603407B2
(en)
|
2017-04-06 |
2023-03-14 |
Regeneron Pharmaceuticals, Inc. |
Stable antibody formulation
|
|
TWI788340B
(zh)
|
2017-04-07 |
2023-01-01 |
美商必治妥美雅史谷比公司 |
抗icos促效劑抗體及其用途
|
|
JP7297672B2
(ja)
|
2017-04-13 |
2023-06-26 |
アジェナス インコーポレイテッド |
抗cd137抗体およびその使用方法
|
|
RU2665790C1
(ru)
*
|
2017-04-17 |
2018-09-04 |
Закрытое Акционерное Общество "Биокад" |
Моноклональное антитело к pd-l1
|
|
US12460208B2
(en)
|
2017-04-18 |
2025-11-04 |
Parr Biotechnology Co., Ltd. |
Immunomodulatory polynucleotides and uses thereof
|
|
CN108728444A
(zh)
|
2017-04-18 |
2018-11-02 |
长春华普生物技术股份有限公司 |
免疫调节性多核苷酸及其应用
|
|
JP2020517256A
(ja)
|
2017-04-19 |
2020-06-18 |
エルスター セラピューティクス, インコーポレイテッド |
多重特異性分子およびその使用
|
|
US10570138B2
(en)
|
2017-04-21 |
2020-02-25 |
Kyn Therapeutics |
Indole AHR inhibitors and uses thereof
|
|
JP2020517699A
(ja)
|
2017-04-26 |
2020-06-18 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
ジスルフィド結合の還元を最小限にする抗体製造法
|
|
AR111419A1
(es)
|
2017-04-27 |
2019-07-10 |
Novartis Ag |
Compuestos fusionados de indazol piridona como antivirales
|
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
|
AR111651A1
(es)
|
2017-04-28 |
2019-08-07 |
Novartis Ag |
Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación
|
|
EP3615566B1
(en)
|
2017-04-28 |
2023-12-20 |
Marengo Therapeutics, Inc. |
Multispecific molecules comprising a non-immunoglobulin heterodimerization domain and uses thereof
|
|
US11021537B2
(en)
|
2017-05-01 |
2021-06-01 |
Agenus Inc. |
Anti-TIGIT antibodies and methods of use thereof
|
|
UY37718A
(es)
|
2017-05-05 |
2018-11-30 |
Novartis Ag |
2-quinolinonas triciclicas como agentes antibacteriales
|
|
KR20200018436A
(ko)
|
2017-05-09 |
2020-02-19 |
테사로, 인코포레이티드 |
암 치료를 위한 조합 요법
|
|
CN121159691A
(zh)
|
2017-05-12 |
2025-12-19 |
哈普恩治疗公司 |
间皮素结合蛋白质
|
|
MX2019013023A
(es)
|
2017-05-12 |
2019-12-18 |
Jiangsu Hengrui Medicine Co |
Proteina de fusion con receptor tgf-?, y uso farmaceutico de la misma.
|
|
WO2018209049A1
(en)
|
2017-05-12 |
2018-11-15 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
KR20200006115A
(ko)
|
2017-05-16 |
2020-01-17 |
브리스톨-마이어스 스큅 컴퍼니 |
항-gitr 효능제 항체에 의한 암의 치료
|
|
JP7189155B2
(ja)
|
2017-05-17 |
2022-12-13 |
アーカス バイオサイエンシズ インコーポレイティド |
癌関連障害の治療のためのキナゾリン-ピラゾール誘導体
|
|
CA3063715A1
(en)
|
2017-05-18 |
2018-11-22 |
Tesaro, Inc. |
Combination therapies for treating cancer
|
|
EP3625246A1
(en)
|
2017-05-18 |
2020-03-25 |
ModernaTX, Inc. |
Polynucleotides encoding tethered interleukin-12 (il12) polypeptides and uses thereof
|
|
CN110691795A
(zh)
|
2017-05-30 |
2020-01-14 |
百时美施贵宝公司 |
包含抗-lag3抗体、pd-1途径抑制剂和免疫治疗剂组合的组合物
|
|
WO2018222722A2
(en)
|
2017-05-30 |
2018-12-06 |
Bristol-Myers Squibb Company |
Compositions comprising an anti-lag-3 antibody or an anti-lag-3 antibody and an anti-pd-1 or anti-pd-l1 antibody
|
|
IL322104A
(en)
|
2017-05-30 |
2025-09-01 |
Bristol Myers Squibb Co |
Treatment of lag-3 positive tumors
|
|
EP3630836A1
(en)
|
2017-05-31 |
2020-04-08 |
Elstar Therapeutics, Inc. |
Multispecific molecules that bind to myeloproliferative leukemia (mpl) protein and uses thereof
|
|
JOP20190279A1
(ar)
|
2017-05-31 |
2019-11-28 |
Novartis Ag |
الصور البلورية من 5-برومو -2، 6-داي (1h-بيرازول -1-يل) بيريميدين -4- أمين وأملاح جديدة
|
|
CA3065929A1
(en)
|
2017-06-01 |
2018-12-06 |
Michael Wayne SAVILLE |
Bispecific antibodies that bind cd123 and cd3
|
|
CA3064331A1
(en)
|
2017-06-01 |
2018-12-06 |
Compugen Ltd. |
Triple combination antibody therapies
|
|
JP2020522486A
(ja)
|
2017-06-01 |
2020-07-30 |
サイトメックス セラピューティクス インコーポレイテッド |
活性化可能抗pdl1抗体、およびその使用方法
|
|
WO2018223004A1
(en)
|
2017-06-01 |
2018-12-06 |
Xencor, Inc. |
Bispecific antibodies that bind cd20 and cd3
|
|
CN110678483B
(zh)
|
2017-06-01 |
2023-09-22 |
百时美施贵宝公司 |
用抗pd-1抗体治疗肿瘤的方法
|
|
WO2018225093A1
(en)
|
2017-06-07 |
2018-12-13 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds as atf4 pathway inhibitors
|
|
EP3634483A1
(en)
|
2017-06-09 |
2020-04-15 |
GlaxoSmithKline Intellectual Property Development Limited |
Combination therapy
|
|
WO2018229715A1
(en)
|
2017-06-16 |
2018-12-20 |
Novartis Ag |
Compositions comprising anti-cd32b antibodies and methods of use thereof
|
|
US11542312B2
(en)
|
2017-06-19 |
2023-01-03 |
Medicenna Therapeutics, Inc. |
IL-2 superagonists in combination with anti-PD-1 antibodies
|
|
GB201709808D0
(en)
|
2017-06-20 |
2017-08-02 |
Kymab Ltd |
Antibodies
|
|
WO2018235056A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
Il-1beta binding antibodies for use in treating cancer
|
|
TW201904993A
(zh)
|
2017-06-22 |
2019-02-01 |
瑞士商諾華公司 |
IL-1β 結合抗體之用途
|
|
US20200172628A1
(en)
|
2017-06-22 |
2020-06-04 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
CN110785187B
(zh)
|
2017-06-22 |
2024-04-05 |
诺华股份有限公司 |
针对cd73的抗体分子及其用途
|
|
WO2019005634A2
(en)
*
|
2017-06-25 |
2019-01-03 |
Systimmune, Inc. |
ANTI-PD-L1 ANTIBODIES AND METHODS OF PREPARATION AND USE
|
|
CN110799543A
(zh)
|
2017-06-26 |
2020-02-14 |
百济神州有限公司 |
肝细胞癌的免疫治疗
|
|
US20200223924A1
(en)
|
2017-06-27 |
2020-07-16 |
Novartis Ag |
Dosage regimens for anti-tim-3 antibodies and uses thereof
|
|
AU2018291081B2
(en)
|
2017-06-27 |
2025-02-20 |
Neuracle Science Co., Ltd. |
Use of anti-FAM19A5 antibodies for treating cancers
|
|
IL271601B2
(en)
|
2017-06-30 |
2024-05-01 |
Bristol Myers Squibb Co |
Amorphous and crystalline forms of ido inhibitors
|
|
JP2020525513A
(ja)
|
2017-07-03 |
2020-08-27 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
癌および他の疾患を治療するためのatf4阻害剤としてのn−(3−(2−(4−クロロフェノキシ)アセトアミドビシクロ[1.1.1]ペンタン−1−イル)−2−シクロブタン−1−カルボキサミド誘導体および関連化合物
|
|
CA3068395A1
(en)
|
2017-07-03 |
2019-01-10 |
Glaxosmithkline Intellectual Property Development Limited |
2-(4-chlorophenoxy)-n-((1-(2-(4-chlorophenoxy)ethynazetidin-3-yl)methyl)acetamide derivatives and related compounds as atf4 inhibitors for treating cancer and other diseases
|
|
NZ761519A
(en)
|
2017-07-14 |
2023-07-28 |
Innate Tumor Immunity Inc |
Nlrp3 modulators
|
|
EP3431088A1
(en)
*
|
2017-07-20 |
2019-01-23 |
Paris Sciences et Lettres - Quartier Latin |
Mntbap for use in inducing a transient immune tolerance
|
|
IL319798A
(en)
|
2017-07-20 |
2025-05-01 |
Novartis Ag |
ANTI-LAG-3 Antibody Dosage Regimens and Their Uses
|
|
WO2019021208A1
(en)
|
2017-07-27 |
2019-01-31 |
Glaxosmithkline Intellectual Property Development Limited |
USEFUL INDAZOLE DERIVATIVES AS PERK INHIBITORS
|
|
CN111148996A
(zh)
|
2017-07-28 |
2020-05-12 |
百时美施贵宝公司 |
用于检查点抑制剂的预测性外周血生物标志物
|
|
CN119019564A
(zh)
|
2017-08-01 |
2024-11-26 |
Ab工作室有限公司 |
双特异性抗体及其用途
|
|
CN111406067B
(zh)
|
2017-08-04 |
2022-11-08 |
健玛保 |
与pd-l1和cd137结合的结合剂及其用途
|
|
EP3661948B1
(en)
|
2017-08-04 |
2022-06-01 |
BicycleTx Limited |
Bicyclic peptide ligands specific for cd137
|
|
WO2019032663A1
(en)
*
|
2017-08-09 |
2019-02-14 |
Orionis Biosciences Inc. |
PD-1 AND PD-L1 BINDING AGENTS
|
|
WO2019035938A1
(en)
|
2017-08-16 |
2019-02-21 |
Elstar Therapeutics, Inc. |
MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF
|
|
JP7269917B2
(ja)
|
2017-08-17 |
2023-05-09 |
イケナ オンコロジー, インコーポレイテッド |
Ahr阻害剤およびその使用
|
|
TWI785098B
(zh)
|
2017-08-18 |
2022-12-01 |
開曼群島商科賽睿生命科學公司 |
Tg02之多晶型
|
|
TWI870011B
(zh)
|
2017-08-25 |
2025-01-11 |
美商戊瑞治療有限公司 |
B7-h4抗體及其使用方法
|
|
KR20200044899A
(ko)
|
2017-08-28 |
2020-04-29 |
브리스톨-마이어스 스큅 컴퍼니 |
암의 치료 및 진단을 위한 tim-3 길항제
|
|
MA50084A
(fr)
|
2017-09-04 |
2020-07-15 |
Agenus Inc |
Récepteurs de lymphocytes t qui se lient à des phosphopeptides spécifiques de la leucémie de lignée mixte (mll) et méthodes d'utilisation de ces derniers
|
|
TW201922721A
(zh)
|
2017-09-07 |
2019-06-16 |
英商葛蘭素史克智慧財產發展有限公司 |
化學化合物
|
|
US11497756B2
(en)
|
2017-09-12 |
2022-11-15 |
Sumitomo Pharma Oncology, Inc. |
Treatment regimen for cancers that are insensitive to BCL-2 inhibitors using the MCL-1 inhibitor alvocidib
|
|
WO2019053617A1
(en)
|
2017-09-12 |
2019-03-21 |
Glaxosmithkline Intellectual Property Development Limited |
CHEMICAL COMPOUNDS
|
|
US20200216542A1
(en)
|
2017-09-20 |
2020-07-09 |
Chugai Seiyaku Kabushiki Kaisha |
Dosage regimen for combination therapy using pd-1 axis binding antagonists and gpc3 targeting agent
|
|
JP7366031B2
(ja)
|
2017-09-22 |
2023-10-20 |
カイメラ セラピューティクス, インコーポレイテッド |
タンパク質分解剤およびそれらの使用
|
|
WO2019060693A1
(en)
|
2017-09-22 |
2019-03-28 |
Kymera Therapeutics, Inc. |
CRBN LIGANDS AND USES THEREOF
|
|
BR112020005284A2
(pt)
|
2017-09-25 |
2020-09-24 |
Chemocentryx, Inc. |
terapia de combinação usando um antagonista do receptor de quimiocina 2 (ccr2) e um inibidor de pd-1/pd-l1
|
|
EA202090839A1
(ru)
*
|
2017-09-27 |
2021-02-04 |
Юниверсити Оф Саутерн Калифорния |
Новые платформы для костимуляции, новые конструкции car и другие улучшения для адаптивной клеточной терапии
|
|
JP2020536066A
(ja)
|
2017-09-30 |
2020-12-10 |
テサロ, インコーポレイテッド |
癌を治療するための併用療法
|
|
CN111182923A
(zh)
|
2017-10-06 |
2020-05-19 |
特沙诺有限公司 |
组合疗法及其用途
|
|
US11203592B2
(en)
|
2017-10-09 |
2021-12-21 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
WO2019074822A1
(en)
|
2017-10-09 |
2019-04-18 |
Bristol-Myers Squibb Company |
INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS AND METHODS OF USE
|
|
EP3694552A1
(en)
|
2017-10-10 |
2020-08-19 |
Tilos Therapeutics, Inc. |
Anti-lap antibodies and uses thereof
|
|
EP3470429A1
(en)
*
|
2017-10-10 |
2019-04-17 |
Numab Innovation AG |
Antibodies targeting pdl1 and methods of use thereof
|
|
CN120248120A
(zh)
*
|
2017-10-10 |
2025-07-04 |
努玛治疗有限公司 |
靶向pdl1的抗体及其使用方法
|
|
WO2019072868A1
(en)
|
2017-10-10 |
2019-04-18 |
Numab Therapeutics AG |
MULTISPECIFIC ANTIBODIES
|
|
CA3075337A1
(en)
|
2017-10-10 |
2019-04-18 |
Numab Therapeutics AG |
Antibodies targeting cd137 and methods of use thereof
|
|
EP3470426A1
(en)
|
2017-10-10 |
2019-04-17 |
Numab Therapeutics AG |
Multispecific antibody
|
|
EP4116327A1
(en)
*
|
2017-10-11 |
2023-01-11 |
Board Of Regents, The University Of Texas System |
Human pd-l1 antibodies and methods of use therefor
|
|
CN111511766B
(zh)
|
2017-10-13 |
2024-06-07 |
Ose免疫疗法 |
修饰的抗SIRPa抗体及其应用
|
|
IL315737A
(en)
|
2017-10-13 |
2024-11-01 |
Harpoon Therapeutics Inc |
B-cell maturation antigen-binding proteins
|
|
EA202090817A1
(ru)
|
2017-10-13 |
2020-09-08 |
Харпун Терапьютикс, Инк. |
Триспецифические белки и способы их применения
|
|
MX2020003361A
(es)
|
2017-10-13 |
2020-07-29 |
Merck Patent Gmbh |
Combinacion de un inhibidor parp y un antagonista de union al eje pd-1.
|
|
KR20200064132A
(ko)
|
2017-10-15 |
2020-06-05 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법
|
|
SG11202003078VA
(en)
|
2017-10-18 |
2020-05-28 |
Alpine Immune Sciences Inc |
Variant icos ligand immunomodulatory proteins and related compositions and methods
|
|
WO2019077062A1
(en)
|
2017-10-18 |
2019-04-25 |
Vivia Biotech, S.L. |
C-CELLS ACTIVATED BY BIT
|
|
CN111655725A
(zh)
|
2017-10-19 |
2020-09-11 |
德比奥药物国际股份有限公司 |
用于治疗癌症的组合产品
|
|
WO2019083971A1
(en)
|
2017-10-23 |
2019-05-02 |
Children's Medical Center Corporation |
METHODS OF TREATING CANCER USING LSD1 INHIBITORS IN COMBINATION WITH IMMUNOTHERAPY
|
|
US20210040205A1
(en)
|
2017-10-25 |
2021-02-11 |
Novartis Ag |
Antibodies targeting cd32b and methods of use thereof
|
|
WO2019089753A2
(en)
|
2017-10-31 |
2019-05-09 |
Compass Therapeutics Llc |
Cd137 antibodies and pd-1 antagonists and uses thereof
|
|
KR20200074214A
(ko)
|
2017-11-01 |
2020-06-24 |
브리스톨-마이어스 스큅 컴퍼니 |
암을 치료하는데 사용하기 위한 면역자극 효능작용 항체
|
|
EP3707138B1
(en)
|
2017-11-06 |
2022-07-13 |
Bristol-Myers Squibb Company |
Isofuranone compounds useful as hpk1 inhibitors
|
|
KR20200084880A
(ko)
|
2017-11-06 |
2020-07-13 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법
|
|
SG11202003477QA
(en)
|
2017-11-14 |
2020-05-28 |
Pfizer |
Ezh2 inhibitor combination therapies
|
|
JP2021502816A
(ja)
|
2017-11-15 |
2021-02-04 |
アディセット バイオ, インコーポレイテッド |
δ3γδT細胞集団の選択的増殖方法及びその組成物
|
|
WO2019097479A1
(en)
|
2017-11-17 |
2019-05-23 |
Novartis Ag |
Novel dihydroisoxazole compounds and their use for the treatment of hepatitis b
|
|
WO2019104289A1
(en)
|
2017-11-27 |
2019-05-31 |
Mersana Therapeutics, Inc. |
Pyrrolobenzodiazepine antibody conjugates
|
|
MX2020005454A
(es)
|
2017-11-27 |
2020-08-27 |
Ose Immunotherapeutics |
Tratamiento de cancer mejorado.
|
|
WO2019108795A1
(en)
|
2017-11-29 |
2019-06-06 |
Beigene Switzerland Gmbh |
Treatment of indolent or aggressive b-cell lymphomas using a combination comprising btk inhibitors
|
|
AU2018375738A1
(en)
|
2017-11-30 |
2020-06-11 |
Novartis Ag |
BCMA-targeting chimeric antigen receptor, and uses thereof
|
|
JP7348899B2
(ja)
|
2017-12-08 |
2023-09-21 |
マレンゴ・セラピューティクス,インコーポレーテッド |
多重特異性分子及びその使用
|
|
TW201938165A
(zh)
|
2017-12-18 |
2019-10-01 |
美商輝瑞股份有限公司 |
治療癌症的方法及組合療法
|
|
GB201721338D0
(en)
|
2017-12-19 |
2018-01-31 |
Kymab Ltd |
Anti-icos Antibodies
|
|
WO2019122882A1
(en)
|
2017-12-19 |
2019-06-27 |
Kymab Limited |
Bispecific antibody for icos and pd-l1
|
|
CN111433210A
(zh)
|
2017-12-20 |
2020-07-17 |
诺华股份有限公司 |
作为抗病毒药的稠合三环吡唑并-二氢吡嗪基-吡啶酮化合物
|
|
EP3727463A1
(en)
|
2017-12-21 |
2020-10-28 |
Mersana Therapeutics, Inc. |
Pyrrolobenzodiazepine antibody conjugates
|
|
IL315310A
(en)
|
2017-12-26 |
2024-10-01 |
Kymera Therapeutics Inc |
Irak degraders and uses thereof
|
|
KR102813744B1
(ko)
|
2017-12-27 |
2025-05-28 |
브리스톨-마이어스 스큅 컴퍼니 |
항-cd40 항체 및 그의 용도
|
|
US12168688B2
(en)
|
2017-12-28 |
2024-12-17 |
Nanjing Legend Biotech Co., Ltd. |
Antibodies and variants thereof against PD-L1
|
|
EP3731850A4
(en)
|
2017-12-29 |
2021-12-01 |
Oncorus, Inc. |
ONCOLYTIC VIRUS DELIVERY OF THERAPEUTIC POLYPEPTIDES
|
|
BR112020013236A2
(pt)
|
2018-01-03 |
2020-12-01 |
Alpine Immune Sciences, Inc. |
proteínas imunomoduladoras de múltiplos domínios e métodos de seu uso
|
|
EP3735590A1
(en)
|
2018-01-04 |
2020-11-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma resistant
|
|
US11447449B2
(en)
|
2018-01-05 |
2022-09-20 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
CA3087765A1
(en)
|
2018-01-08 |
2019-07-11 |
Chemocentryx, Inc. |
Methods of treating solid tumors with ccr2 antagonists
|
|
US20190269664A1
(en)
|
2018-01-08 |
2019-09-05 |
Chemocentryx, Inc. |
Methods of treating solid tumors with ccr2 antagonists
|
|
CN112218651A
(zh)
|
2018-01-08 |
2021-01-12 |
诺华公司 |
用于与嵌合抗原受体疗法组合的免疫增强rna
|
|
EP3737692A4
(en)
|
2018-01-09 |
2021-09-29 |
Elstar Therapeutics, Inc. |
CALRETICULIN AND MODIFIED T-LYMPHOCYTES BINDING CONSTRUCTIONS FOR THE TREATMENT OF DISEASES
|
|
US11407723B2
(en)
|
2018-01-09 |
2022-08-09 |
Shuttle Pharmaceuticals, Inc. |
Selective histone deacetylase inhibitors for the treatment of human disease
|
|
EP3737689A4
(en)
|
2018-01-09 |
2021-12-01 |
Cue Biopharma, Inc. |
MULTIMERIC T CELL-MODULATING POLYPEPTIDES AND METHOD OF USING THEREOF
|
|
CA3087105A1
(en)
|
2018-01-10 |
2019-07-18 |
Jiangsu Hengrui Medicine Co., Ltd. |
Pd-l1 antibody, antigen-binding fragment thereof, and pharmaceutical use thereof
|
|
WO2019140229A1
(en)
|
2018-01-12 |
2019-07-18 |
Bristol-Myers Squibb Company |
Antibodies against tim3 and uses thereof
|
|
WO2019140380A1
(en)
|
2018-01-12 |
2019-07-18 |
Kymera Therapeutics, Inc. |
Protein degraders and uses thereof
|
|
EP3737696A1
(en)
|
2018-01-12 |
2020-11-18 |
Bristol-Myers Squibb Company |
Combination therapy with anti-il-8 antibodies and anti-pd-1 antibodies for treating cancer
|
|
WO2019140387A1
(en)
|
2018-01-12 |
2019-07-18 |
Kymera Therapeutics, Inc. |
Crbn ligands and uses thereof
|
|
WO2019143607A1
(en)
|
2018-01-16 |
2019-07-25 |
Bristol-Myers Squibb Company |
Methods of treating cancer with antibodies against tim3
|
|
EP3743076A1
(en)
|
2018-01-22 |
2020-12-02 |
Bristol-Myers Squibb Company |
Compositions and methods of treating cancer
|
|
AU2019210332A1
(en)
|
2018-01-22 |
2020-09-10 |
Pascal Biosciences Inc. |
Cannabinoids and derivatives for promoting immunogenicity of tumor and infected cells
|
|
SG11202006701TA
(en)
|
2018-01-29 |
2020-08-28 |
Merck Patent Gmbh |
Gcn2 inhibitors and uses thereof
|
|
MX2020007797A
(es)
|
2018-01-29 |
2020-09-18 |
Merck Patent Gmbh |
Inhibidores de la cinasa 2 de control general no desrepresible (gcn2) y usos de los mismos.
|
|
AU2019215031B2
(en)
|
2018-01-31 |
2025-10-09 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
|
KR20200128014A
(ko)
|
2018-01-31 |
2020-11-11 |
셀진 코포레이션 |
입양 세포 요법 및 체크포인트 억제제를 이용한 병용 요법
|
|
CA3090652A1
(en)
|
2018-02-06 |
2019-08-15 |
The General Hospital Corporation |
Repeat rna as biomarkers of tumor immune response
|
|
US20200405806A1
(en)
|
2018-02-08 |
2020-12-31 |
Bristol-Myers Squibb Company |
Combination of a tetanus toxoid, anti-ox40 antibody and/or anti-pd-1 antibody to treat tumors
|
|
WO2019160956A1
(en)
|
2018-02-13 |
2019-08-22 |
Novartis Ag |
Chimeric antigen receptor therapy in combination with il-15r and il15
|
|
JP7417527B2
(ja)
|
2018-02-16 |
2024-01-18 |
アーカス バイオサイエンシズ インコーポレイティド |
アゾロピリミジン化合物による投薬
|
|
EP3756012A1
(en)
|
2018-02-21 |
2020-12-30 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sk1 as biomarker for predicting response to immunecheckpoint inhibitors
|
|
CN111741978A
(zh)
|
2018-02-21 |
2020-10-02 |
戊瑞治疗有限公司 |
B7-h4抗体制剂
|
|
SG11202007678QA
(en)
|
2018-02-23 |
2020-09-29 |
Bicycletx Ltd |
Multimeric bicyclic peptide ligands
|
|
WO2019165315A1
(en)
|
2018-02-23 |
2019-08-29 |
Syntrix Biosystems Inc. |
Method for treating cancer using chemokine antagonists alone or in combination
|
|
US20200407365A1
(en)
|
2018-02-28 |
2020-12-31 |
Novartis Ag |
Indole-2-carbonyl compounds and their use for the treatment of hepatitis b
|
|
CA3091801A1
(en)
|
2018-03-02 |
2019-09-06 |
Five Prime Therapeutics, Inc. |
B7-h4 antibodies and methods of use thereof
|
|
SG11202008113RA
(en)
|
2018-03-05 |
2020-09-29 |
Arcus Biosciences Inc |
Arginase inhibitors
|
|
RU2020133451A
(ru)
|
2018-03-12 |
2022-04-12 |
Инститьют Насьонал Де Ла Санте Et De La Решерш Медикаль (Инсерм) |
Применение терапевтически эффективной комбинации химиотерапиии и ингибитора контрольной точки иммунного ответа с миметиком ограничения калорийности для лечения рака
|
|
CN112105646A
(zh)
|
2018-03-13 |
2020-12-18 |
Ose免疫疗法 |
抗人SIRPa v1抗体的用途和生产抗SIRPa v1抗体的方法
|
|
EP3765516A2
(en)
|
2018-03-14 |
2021-01-20 |
Elstar Therapeutics, Inc. |
Multifunctional molecules and uses thereof
|
|
US10738128B2
(en)
|
2018-03-14 |
2020-08-11 |
Surface Oncology, Inc. |
Antibodies that bind CD39 and uses thereof
|
|
EP3765019A1
(en)
|
2018-03-14 |
2021-01-20 |
Merck Patent GmbH |
Compounds and uses thereof to treat tumors in a subject
|
|
EP3765517A1
(en)
|
2018-03-14 |
2021-01-20 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
JP2021518380A
(ja)
*
|
2018-03-19 |
2021-08-02 |
アベオメ コーポレーション |
プログラム細胞死リガンド1(pd−l1)に対する高親和性中和モノクローナル抗体、及びその使用
|
|
KR102874694B1
(ko)
|
2018-03-21 |
2025-10-23 |
파이브 프라임 테라퓨틱스, 인크. |
산성 pH에서 VISTA에 결합하는 항체
|
|
KR102879521B1
(ko)
|
2018-03-22 |
2025-11-03 |
서피스 온콜로지, 엘엘씨 |
항-il-27 항체 및 이의 용도
|
|
TW202003565A
(zh)
|
2018-03-23 |
2020-01-16 |
美商必治妥美雅史谷比公司 |
抗mica及/或micb抗體及其用途
|
|
EP4501355A3
(en)
|
2018-03-23 |
2025-04-30 |
Board Of Regents, The University Of Texas System |
Dual specificity antibodies to pd-l1 and pd-l2 and methods of use therefor
|
|
CN119101158A
(zh)
|
2018-03-23 |
2024-12-10 |
得克萨斯州大学系统董事会 |
人pd-l2抗体及其使用方法
|
|
CN117586412A
(zh)
|
2018-03-23 |
2024-02-23 |
得克萨斯州大学系统董事会 |
针对人pd-l1和pd-l2的双重特异性抗体及其使用方法
|
|
TW202003569A
(zh)
|
2018-03-30 |
2020-01-16 |
荷蘭商美勒斯公司 |
多價抗體
|
|
US20210032344A1
(en)
|
2018-03-30 |
2021-02-04 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
EP3774903A1
(en)
|
2018-04-04 |
2021-02-17 |
Bristol-Myers Squibb Company |
Anti-cd27 antibodies and uses thereof
|
|
WO2019193541A1
(en)
|
2018-04-06 |
2019-10-10 |
Glaxosmithkline Intellectual Property Development Limited |
Bicyclic aromatic ring derivatives of formula (i) as atf4 inhibitors
|
|
WO2019193540A1
(en)
|
2018-04-06 |
2019-10-10 |
Glaxosmithkline Intellectual Property Development Limited |
Heteroaryl derivatives of formula (i) as atf4 inhibitors
|
|
KR20200142542A
(ko)
|
2018-04-12 |
2020-12-22 |
브리스톨-마이어스 스큅 컴퍼니 |
Cd73 길항제 항체 및 pd-1/pd-l1 축 길항제 항체에 의한 항암 조합 요법
|
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
|
CN112292128A
(zh)
|
2018-04-16 |
2021-01-29 |
阿瑞斯医疗有限公司 |
Ep4抑制剂和其用途
|
|
KR20210011919A
(ko)
|
2018-04-17 |
2021-02-02 |
셀덱스 쎄라퓨틱스, 인크. |
항-cd27 항체 및 항-pd-l1 항체 및 이중특이적 작제물
|
|
MA52289A
(fr)
|
2018-04-18 |
2021-02-24 |
Xencor Inc |
Protéines de fusion fc hétérodimères il-15/il-15ra et leurs utilisations
|
|
KR20210010862A
(ko)
|
2018-04-18 |
2021-01-28 |
젠코어 인코포레이티드 |
IL-15/IL-15Rα Fc-융합 단백질 및 PD-1 항원 결합 도메인을 함유하는 PD-1 표적화 이종이량체 융합 단백질 및 이의 용도
|
|
US10907161B2
(en)
|
2018-04-19 |
2021-02-02 |
Checkmate Pharmaceuticals, Inc. |
Synthetic RIG-I-like receptor agonists
|
|
AU2019261582A1
(en)
|
2018-04-25 |
2020-11-12 |
Innate Tumor Immunity, Inc. |
NLRP3 modulators
|
|
CA3096909A1
(en)
|
2018-04-26 |
2019-10-31 |
Agenus Inc. |
Heat shock protein-binding peptide compositions and methods of use thereof
|
|
US12037323B2
(en)
|
2018-05-03 |
2024-07-16 |
Bristol-Myers Squibb Company |
Uracil derivatives as Mer-AXL inhibitors
|
|
US20210246208A1
(en)
|
2018-05-04 |
2021-08-12 |
Merck Patent Gmbh |
Combined inhibition of pd-1/pd-l1, tgfb and dna-pk for the treatment of cancer
|
|
AR126019A1
(es)
|
2018-05-30 |
2023-09-06 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
US20190365719A1
(en)
|
2018-06-01 |
2019-12-05 |
Massachusetts Institute Of Technology |
Combination treatments of hsp90 inhibitors for enhancing tumor immunogenicity and methods of use thereof
|
|
BR112020024351A2
(pt)
|
2018-06-01 |
2021-02-23 |
Novartis Ag |
moléculas de ligação contra bcma e usos das mesmas
|
|
AU2019276656A1
(en)
|
2018-06-01 |
2021-01-07 |
Novartis Ag |
Dosing of a bispecific antibody that bind CD123 and CD3
|
|
US11180531B2
(en)
|
2018-06-22 |
2021-11-23 |
Bicycletx Limited |
Bicyclic peptide ligands specific for Nectin-4
|
|
CN112584861A
(zh)
*
|
2018-06-22 |
2021-03-30 |
维里亚德公司 |
使用组合疗法治疗癌症的方法
|
|
CN112654621B
(zh)
|
2018-06-27 |
2024-05-14 |
百时美施贵宝公司 |
可作为t细胞活化剂的经取代萘啶酮化合物
|
|
EA202190137A1
(ru)
|
2018-06-27 |
2021-05-17 |
Бристол-Маерс Сквибб Компани |
Нафтиридиноновые соединения для применения в качестве активаторов t-клеток
|
|
US12202879B2
(en)
|
2018-06-29 |
2025-01-21 |
Kookmin University Industry Academy Cooperation Foundation |
PD-L1 variants with enhanced binding affinity to PD-1
|
|
EP3818083A2
(en)
|
2018-07-03 |
2021-05-12 |
Elstar Therapeutics, Inc. |
Anti-tcr antibody molecules and uses thereof
|
|
EP3817822A4
(en)
|
2018-07-06 |
2022-07-27 |
Kymera Therapeutics, Inc. |
PROTEIN DEGRADANTS AND USES THEREOF
|
|
US11292792B2
(en)
|
2018-07-06 |
2022-04-05 |
Kymera Therapeutics, Inc. |
Tricyclic CRBN ligands and uses thereof
|
|
EP3820904A2
(en)
|
2018-07-09 |
2021-05-19 |
Five Prime Therapeutics, Inc. |
Antibodies binding to ilt4
|
|
CA3105942A1
(en)
|
2018-07-09 |
2020-01-16 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
BR112020026947B1
(pt)
|
2018-07-10 |
2022-11-22 |
Novartis Ag |
Derivados de 3-(5-hidróxi-1-oxoisoindolin-2-il)piperidina-2,6-diona, e composição farmacêutica
|
|
CA3106108A1
(en)
*
|
2018-07-11 |
2020-01-16 |
Momenta Pharmaceuticals, Inc. |
Compositions and methods related to engineered fc-antigen binding domain constructs targeted to pd-l1
|
|
CN121203021A
(zh)
|
2018-07-11 |
2025-12-26 |
戊瑞治疗有限公司 |
在酸性pH下结合至VISTA的抗体
|
|
WO2020014471A1
(en)
|
2018-07-11 |
2020-01-16 |
The Brigham And Women's Hospital, Inc. |
Methods and compositions for delivery of agents across the blood-brain barrier
|
|
GB201811450D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Delta Ltd |
Mesothelin and CD137 binding molecules
|
|
GB201811403D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Antibody molecules
|
|
US12344672B2
(en)
|
2018-07-12 |
2025-07-01 |
Invox Pharma Limited |
Antibody molecules that bind PD-L1 and CD137
|
|
MX2021000399A
(es)
|
2018-07-12 |
2021-05-27 |
F Star Therapeutics Ltd |
Moleculas de anticuerpo que se unen a cd137 y ox40.
|
|
GB201811410D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
OX40 Binding molecules
|
|
GB201811415D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Anti-Mesothelin Anti bodies
|
|
GB201811408D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
CD137 Binding Molecules
|
|
WO2020014583A1
(en)
|
2018-07-13 |
2020-01-16 |
Bristol-Myers Squibb Company |
Ox-40 agonist, pd-1 pathway inhibitor and ctla-4 inhibitor combination for use in a mehtod of treating a cancer or a solid tumor
|
|
CA3106366A1
(en)
|
2018-07-18 |
2020-01-23 |
Arcus Biosciences, Inc. |
Solid forms of an azolopyrimidine compound
|
|
JP7072715B2
(ja)
|
2018-07-20 |
2022-05-20 |
サーフィス オンコロジー インコーポレイテッド |
抗cd112r組成物及び方法
|
|
US12059420B2
(en)
|
2018-07-23 |
2024-08-13 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
WO2020023356A1
(en)
|
2018-07-23 |
2020-01-30 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
WO2020020307A1
(en)
|
2018-07-25 |
2020-01-30 |
I-Mab Biopharma Co., Ltd. |
Anti-cd73 anti-pd-l1 bispecific antibodies
|
|
JP2021532143A
(ja)
|
2018-07-26 |
2021-11-25 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
癌の処置のためのlag−3併用療法
|
|
US20210317233A1
(en)
|
2018-07-31 |
2021-10-14 |
The University Of Tokyo |
Super Versatile Method for Imparting New Binding Specificity to Antibody
|
|
WO2020031107A1
(en)
|
2018-08-08 |
2020-02-13 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds
|
|
CA3109778A1
(en)
|
2018-08-16 |
2020-02-20 |
Innate Tumor Immunity, Inc. |
Substitued 4-amino-1h-imidazo[4,5-c]quinoline compounds and improved methods for their preparation
|
|
EP3837015B1
(en)
|
2018-08-16 |
2024-02-14 |
Innate Tumor Immunity, Inc. |
Imidazo[4,5-c]quinoline derived nlrp3-modulators
|
|
EP3837014B1
(en)
|
2018-08-16 |
2022-10-19 |
Innate Tumor Immunity, Inc. |
Imidazo[4,5-c]quinoline derived nlrp3-modulators
|
|
JP7488534B2
(ja)
*
|
2018-08-20 |
2024-05-22 |
1グローブ バイオメディカル カンパニー, リミテッド |
新規ながん免疫療法抗体組成物
|
|
KR102715542B1
(ko)
|
2018-08-20 |
2024-10-08 |
화이자 인코포레이티드 |
항-gdf15 항체, 조성물 및 사용 방법
|
|
CN112955221A
(zh)
|
2018-08-27 |
2021-06-11 |
皮里斯制药有限公司 |
包含cd137/her2双特异性试剂和pd-1轴抑制剂的组合疗法及其用途
|
|
US11253525B2
(en)
|
2018-08-29 |
2022-02-22 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
US10959986B2
(en)
|
2018-08-29 |
2021-03-30 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
TW202031273A
(zh)
|
2018-08-31 |
2020-09-01 |
美商艾歐凡斯生物治療公司 |
抗pd-1抗體難治療性之非小細胞肺癌(nsclc)病患的治療
|
|
WO2020048942A1
(en)
|
2018-09-04 |
2020-03-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for enhancing cytotoxic t lymphocyte-dependent immune responses
|
|
US11331269B2
(en)
|
2018-09-06 |
2022-05-17 |
Massachusetts Institute Of Technology |
Methods and compositions targeting lung microbiota and its responding immune pathways for lung cancer treatment
|
|
EP3846793B1
(en)
|
2018-09-07 |
2024-01-24 |
PIC Therapeutics, Inc. |
Eif4e inhibitors and uses thereof
|
|
JP7476171B2
(ja)
*
|
2018-09-07 |
2024-04-30 |
ザ ジェネラル ホスピタル コーポレイション |
免疫チェックポイント阻害のための組成物および方法
|
|
AU2019339777B2
(en)
|
2018-09-12 |
2022-09-01 |
Novartis Ag |
Antiviral pyridopyrazinedione compounds
|
|
CN109053891B
(zh)
*
|
2018-09-17 |
2021-12-21 |
苏州泓迅生物科技股份有限公司 |
一种抗pd-l1抗体及其制备方法和应用
|
|
US20220073638A1
(en)
|
2018-09-19 |
2022-03-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical composition for the treatment of cancers resistant to immune checkpoint therapy
|
|
SG11202101787XA
(en)
|
2018-09-20 |
2021-04-29 |
Iovance Biotherapeutics Inc |
Expansion of tils from cryopreserved tumor samples
|
|
WO2020061482A1
(en)
|
2018-09-21 |
2020-03-26 |
Harpoon Therapeutics, Inc. |
Egfr binding proteins and methods of use
|
|
AU2019346466A1
(en)
|
2018-09-25 |
2021-05-20 |
Harpoon Therapeutics, Inc. |
DLL3 binding proteins and methods of use
|
|
CA3114024A1
(en)
|
2018-09-26 |
2020-04-02 |
Merck Patent Gmbh |
Combination of a pd-1 antagonist, an atr inhibitor and a platinating agent for the treatment of cancer
|
|
JP7465272B2
(ja)
|
2018-09-27 |
2024-04-10 |
マレンゴ・セラピューティクス,インコーポレーテッド |
Csf1r/ccr2多特異性抗体
|
|
EP3860578A1
(en)
|
2018-10-01 |
2021-08-11 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Use of inhibitors of stress granule formation for targeting the regulation of immune responses
|
|
JP7612571B2
(ja)
|
2018-10-03 |
2025-01-14 |
ゼンコア インコーポレイテッド |
Il-12ヘテロ二量体fc-融合タンパク質
|
|
US20210395392A1
(en)
|
2018-10-09 |
2021-12-23 |
Bristol-Myers Squibb Company |
Anti-mertk antibodies for treating cancer
|
|
CN113164780A
(zh)
|
2018-10-10 |
2021-07-23 |
泰洛斯治疗公司 |
抗lap抗体变体及其用途
|
|
CR20210239A
(es)
|
2018-10-12 |
2021-12-15 |
Xencor Inc |
Proteínas de fusión de il-15/il-15ralfa-fc dirigidas a pd-1 y usos de las mismas en terapias combinadas
|
|
WO2020079581A1
(en)
|
2018-10-16 |
2020-04-23 |
Novartis Ag |
Tumor mutation burden alone or in combination with immune markers as biomarkers for predicting response to targeted therapy
|
|
WO2020081493A1
(en)
|
2018-10-16 |
2020-04-23 |
Molecular Templates, Inc. |
Pd-l1 binding proteins
|
|
EP3866850B1
(en)
|
2018-10-19 |
2024-07-24 |
Bristol-Myers Squibb Company |
Combination therapy for melanoma
|
|
US20210324081A1
(en)
|
2018-10-22 |
2021-10-21 |
Glaxosmithkline Intellectual Property Development Limited |
Dosing
|
|
CN112912403A
(zh)
|
2018-10-23 |
2021-06-04 |
百时美施贵宝公司 |
治疗肿瘤的方法
|
|
MX2021004906A
(es)
|
2018-10-29 |
2021-09-10 |
Mersana Therapeutics Inc |
Conjugados de anticuerpo modificado con cisteína-fármaco con enlazadores que contienen péptidos.
|
|
WO2020089811A1
(en)
|
2018-10-31 |
2020-05-07 |
Novartis Ag |
Dc-sign antibody drug conjugates
|
|
WO2020093024A2
(en)
|
2018-11-01 |
2020-05-07 |
Merck Patent Gmbh |
Methods of administering anti-tim-3 antibodies
|
|
CA3117429A1
(en)
|
2018-11-01 |
2020-05-07 |
Merck Patent Gmbh |
Anti-tim-3 antibodies
|
|
WO2020095184A1
(en)
|
2018-11-05 |
2020-05-14 |
Pfizer Inc. |
Combinations for treating cancer
|
|
JP2022509917A
(ja)
|
2018-11-05 |
2022-01-25 |
ファイザー・インク |
がんを処置するための組合せ
|
|
WO2020094744A1
(en)
|
2018-11-06 |
2020-05-14 |
Genmab A/S |
Antibody formulation
|
|
WO2020097409A2
(en)
|
2018-11-08 |
2020-05-14 |
Modernatx, Inc. |
Use of mrna encoding ox40l to treat cancer in human patients
|
|
BR112021008288A2
(pt)
|
2018-11-09 |
2021-08-10 |
Jiangsu Hengrui Medicine Co., Ltd. |
composição farmacêutica de proteína de fusão do receptor tgf-ss e uso da mesma
|
|
SG11202105078XA
(en)
|
2018-11-14 |
2021-06-29 |
Bayer Ag |
Pharmaceutical combination of anti-ceacam6 and either anti-pd-1 or anti-pd-l1 antibodies for the treatment of cancer
|
|
WO2020102375A1
(en)
|
2018-11-14 |
2020-05-22 |
Regeneron Pharmaceuticals, Inc. |
Intralesional administration of pd-1 inhibitors for treating skin cancer
|
|
PE20211284A1
(es)
|
2018-11-16 |
2021-07-19 |
Bristol Myers Squibb Co |
Anticuerpos anti-nkg2a y usos de los mismos
|
|
EP3880231A1
(en)
|
2018-11-16 |
2021-09-22 |
NeoImmuneTech, Inc. |
Method of treating a tumor with a combination of il-7 protein and an immune checkpoint inhibitor
|
|
TWI828800B
(zh)
|
2018-11-16 |
2024-01-11 |
美商阿克思生物科學有限公司 |
Arg1及/或arg2之抑制劑
|
|
WO2020104479A1
(en)
|
2018-11-20 |
2020-05-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating cancers and resistant cancers with anti transferrin receptor 1 antibodies
|
|
CN113056288A
(zh)
|
2018-11-20 |
2021-06-29 |
康奈尔大学 |
放射性核素的大环配合物及其在癌症的放射治疗中的应用
|
|
EP3883964A1
(en)
|
2018-11-20 |
2021-09-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Bispecific antibody targeting transferrin receptor 1 and soluble antigen
|
|
EP3886842A1
(en)
|
2018-11-26 |
2021-10-06 |
Debiopharm International SA |
Combination treatment of hiv infections
|
|
EP3887823B1
(en)
|
2018-11-28 |
2024-01-17 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and kit for assaying lytic potential of immune effector cells
|
|
KR20250167680A
(ko)
|
2018-11-30 |
2025-12-01 |
카이메라 쎄라퓨틱스 인코포레이티드 |
Irak 분해제 및 이의 용도
|
|
JP7406556B2
(ja)
|
2018-11-30 |
2023-12-27 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド |
Hiv療法に有用な化合物
|
|
KR102835299B1
(ko)
|
2018-12-04 |
2025-07-18 |
브리스톨-마이어스 스큅 컴퍼니 |
다중 동위원소체 반응 모니터링에 의한 샘플내 보정 곡선을 사용한 분석 방법
|
|
EP3890749B1
(en)
|
2018-12-04 |
2025-10-29 |
Sumitomo Pharma America, Inc. |
Cdk9 inhibitors and polymorphs thereof for use as agents for treatment of cancer
|
|
WO2020115261A1
(en)
|
2018-12-07 |
2020-06-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
WO2020115262A1
(en)
|
2018-12-07 |
2020-06-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of cd26 and cd39 as new phenotypic markers for assessing maturation of foxp3+ t cells and uses thereof for diagnostic purposes
|
|
WO2020120592A1
(en)
|
2018-12-12 |
2020-06-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating melanoma
|
|
GB201820288D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicycle Tx Ltd |
Bicycle peptide ligaands specific for MT1-MMP
|
|
WO2020123011A1
(en)
|
2018-12-13 |
2020-06-18 |
Surface Oncology, Inc. |
Anti-il-27 antibodies and uses thereof
|
|
GB201820325D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for psma
|
|
GB201820295D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for MT1-MMP
|
|
US20220047556A1
(en)
|
2018-12-17 |
2022-02-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sulconazole as a furin inhibitor
|
|
KR20210104704A
(ko)
|
2018-12-19 |
2021-08-25 |
바이엘 악티엔게젤샤프트 |
항 ceacam6 및 tim3 항체의 제약 조합물
|
|
WO2020127411A1
(en)
|
2018-12-19 |
2020-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating cancers by immuno-modulation using antibodies against cathespin-d
|
|
EP3670659A1
(en)
|
2018-12-20 |
2020-06-24 |
Abivax |
Biomarkers, and uses in treatment of viral infections, inflammations, or cancer
|
|
WO2020132646A1
(en)
|
2018-12-20 |
2020-06-25 |
Xencor, Inc. |
Targeted heterodimeric fc fusion proteins containing il-15/il-15ra and nkg2d antigen binding domains
|
|
BR112021011874A2
(pt)
|
2018-12-20 |
2021-09-08 |
Novartis Ag |
Regime de dosagem e combinação farmacêutica compreendendo derivados de 3-(1-oxoisoindolin-2-il)piperidina-2,6-diona
|
|
CA3119582A1
(en)
|
2018-12-21 |
2020-06-25 |
Novartis Ag |
Use of il-1.beta. binding antibodies
|
|
WO2020128613A1
(en)
|
2018-12-21 |
2020-06-25 |
Novartis Ag |
Use of il-1beta binding antibodies
|
|
CA3119584A1
(en)
|
2018-12-21 |
2020-06-25 |
Novartis Ag |
Use of il-1 beta antibodies in the treatment or prevention of myelodysplastic syndrome
|
|
WO2020127885A1
(en)
|
2018-12-21 |
2020-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Compositions for treating cancers and resistant cancers
|
|
WO2020128893A1
(en)
|
2018-12-21 |
2020-06-25 |
Pfizer Inc. |
Combination treatments of cancer comprising a tlr agonist
|
|
US20220054524A1
(en)
|
2018-12-21 |
2022-02-24 |
Onxeo |
New conjugated nucleic acid molecules and their uses
|
|
JP2022514618A
(ja)
|
2018-12-21 |
2022-02-14 |
バイスクルテクス・リミテッド |
Pd-l1に特異的な二環式ペプチドリガンド
|
|
WO2020128637A1
(en)
|
2018-12-21 |
2020-06-25 |
Novartis Ag |
Use of il-1 binding antibodies in the treatment of a msi-h cancer
|
|
MX2021007860A
(es)
|
2018-12-28 |
2021-10-26 |
Transgene |
Poxvirux deficiente en m2.
|
|
WO2020150113A1
(en)
|
2019-01-14 |
2020-07-23 |
Innate Tumor Immunity, Inc. |
Substituted quinazolines as nlrp3 modulators, for use in the treatment of cancer
|
|
US12391675B2
(en)
|
2019-01-14 |
2025-08-19 |
Innate Tumor Immunity, Inc. |
NLRP3 modulators
|
|
EP3911642A1
(en)
|
2019-01-14 |
2021-11-24 |
Innate Tumor Immunity, Inc. |
Nlrp3 modulators
|
|
EP3911417B1
(en)
|
2019-01-14 |
2022-10-26 |
Innate Tumor Immunity, Inc. |
Heterocyclic nlrp3 modulators , for use in the treatment of cancer
|
|
ES3011707T3
(en)
|
2019-01-15 |
2025-04-08 |
Inst Nat Sante Rech Med |
Mutated interleukin-34 (il-34) polypeptides and uses thereof in therapy
|
|
AU2020208637A1
(en)
|
2019-01-18 |
2021-09-09 |
Dracen Pharmaceuticals, Inc. |
Combinaton therapy with a don prodrug and an immune checkpoint inhibitor
|
|
US12463463B2
(en)
|
2019-01-28 |
2025-11-04 |
Ab Therapeutics, Inc. |
Bispecific antibodies and uses thereof
|
|
JP7442536B2
(ja)
|
2019-01-30 |
2024-03-04 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
ガンを患っている被験体が免疫チェックポイント阻害剤で反応を達成するかを特定するための方法及び組成物
|
|
CN113365659B
(zh)
*
|
2019-01-31 |
2023-08-18 |
正大天晴药业集团股份有限公司 |
抗pd-l1抗体治疗头颈癌的用途
|
|
WO2020161083A1
(en)
|
2019-02-04 |
2020-08-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for modulating blood-brain barrier
|
|
AU2020221247B2
(en)
|
2019-02-12 |
2024-12-12 |
Sumitomo Pharma America, Inc. |
Formulations comprising heterocyclic protein kinase inhibitors
|
|
WO2020165370A1
(en)
|
2019-02-13 |
2020-08-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for selecting a cancer treatment in a subject suffering from cancer
|
|
WO2020165833A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
AU2020222346B2
(en)
|
2019-02-15 |
2021-12-09 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
ES2973104T3
(es)
|
2019-02-18 |
2024-06-18 |
Medivir Ab |
Combinación de fármacos para su uso en un método de tratamiento de cáncer de hígado
|
|
WO2020169472A2
(en)
|
2019-02-18 |
2020-08-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of inducing phenotypic changes in macrophages
|
|
MX2021009967A
(es)
|
2019-02-19 |
2021-11-12 |
Myst Therapeutics Llc |
Metodos para producir celulas t autologas utiles para tratar cancer y composiciones de las mismas.
|
|
SG11202108955QA
(en)
|
2019-02-21 |
2021-09-29 |
Marengo Therapeutics Inc |
Antibody molecules that bind to nkp30 and uses thereof
|
|
SG11202109085YA
(en)
*
|
2019-02-21 |
2021-09-29 |
Eucure Beijing Biopharma Co Ltd |
Anti-pd-l1 antibody and use thereof
|
|
CN119661722A
(zh)
|
2019-02-21 |
2025-03-21 |
马伦戈治疗公司 |
结合t细胞相关癌细胞的多功能分子及其用途
|
|
AU2020228296B2
(en)
|
2019-02-28 |
2025-10-02 |
Regeneron Pharmaceuticals, Inc. |
Administration of PD-1 inhibitors for treating skin cancer
|
|
CN113677707A
(zh)
|
2019-03-06 |
2021-11-19 |
瑞泽恩制药公司 |
用于在治疗癌症中增强效力的il-4/il-13途径抑制剂
|
|
WO2020185859A1
(en)
|
2019-03-12 |
2020-09-17 |
Arcus Biosciences, Inc. |
Treatment of oncogene-driven cancers
|
|
CN113795264A
(zh)
|
2019-03-19 |
2021-12-14 |
瓦尔希伯伦私人肿瘤研究基金会 |
采用Omomyc和结合PD-1或CTLA-4的抗体治疗癌症的联合疗法
|
|
WO2020191326A1
(en)
|
2019-03-20 |
2020-09-24 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Treatment of acute myeloid leukemia (aml) with venetoclax failure
|
|
CA3133460A1
(en)
|
2019-03-22 |
2020-10-01 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Compositions comprising pkm2 modulators and methods of treatment using the same
|
|
EP3946619A1
(en)
|
2019-03-26 |
2022-02-09 |
The Regents Of The University Of Michigan |
Small molecule degraders of stat3
|
|
KR20210146348A
(ko)
|
2019-03-28 |
2021-12-03 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법
|
|
WO2020198676A1
(en)
|
2019-03-28 |
2020-10-01 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
EP3947463A4
(en)
|
2019-03-29 |
2022-12-21 |
Arcus Biosciences, Inc. |
CANCER TREATMENT USING AN IDENTIFIED ADENOSINE IMPRESSION
|
|
EP3947403A1
(en)
|
2019-03-29 |
2022-02-09 |
The Regents Of The University Of Michigan |
Stat3 protein degraders
|
|
MX2021011608A
(es)
|
2019-03-29 |
2021-12-10 |
Myst Therapeutics Llc |
Metodos ex vivo para producir celulas t terapeuticas y composiciones y metodos afines.
|
|
US20220177978A1
(en)
|
2019-04-02 |
2022-06-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of predicting and preventing cancer in patients having premalignant lesions
|
|
EP3946462A1
(en)
|
2019-04-02 |
2022-02-09 |
BicycleTX Limited |
Bicycle toxin conjugates and uses thereof
|
|
EP3947640A4
(en)
|
2019-04-02 |
2022-12-14 |
The Brigham & Women's Hospital, Inc. |
PROCEDURE FOR DETERMINING THE PROGRESSION OF PRIMARY MELANOMA
|
|
CA3135802A1
(en)
|
2019-04-05 |
2020-10-08 |
Kymera Therapeutics, Inc. |
Stat degraders and uses thereof
|
|
WO2020208060A1
(en)
|
2019-04-09 |
2020-10-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sk2 inhibitors in combination with immune checkpoint blockade therapy for the treatment of cancer
|
|
BR112021020225A2
(pt)
|
2019-04-12 |
2021-12-07 |
Vascular Biogenics Ltd |
Métodos de terapia antitumoral
|
|
WO2020212484A1
(en)
|
2019-04-17 |
2020-10-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treatment of nlrp3 inflammasome mediated il-1beta dependent disorders
|
|
US11208486B2
(en)
*
|
2019-04-26 |
2021-12-28 |
I-Mab Biopharma Us Limited |
Human PD-L1 antibodies
|
|
EP3963109A1
(en)
|
2019-04-30 |
2022-03-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
BR112021022135A2
(pt)
*
|
2019-05-06 |
2023-02-28 |
Univ Brown |
Anticorpos biespecíficos contra chi3l1 e pd1 com efeitos citotóxicos mediados por célula t realçados sobre células de tumor
|
|
JP2022534889A
(ja)
|
2019-05-24 |
2022-08-04 |
ファイザー・インコーポレイテッド |
Cdk阻害剤を使用した組合せ療法
|
|
CN114127315A
(zh)
|
2019-05-30 |
2022-03-01 |
百时美施贵宝公司 |
鉴定适合于免疫肿瘤学(i-o)疗法的受试者的方法
|
|
JP2022534967A
(ja)
|
2019-05-30 |
2022-08-04 |
ブリストル-マイヤーズ スクイブ カンパニー |
多腫瘍遺伝子シグネチャーおよびその使用
|
|
US20220233691A1
(en)
|
2019-05-30 |
2022-07-28 |
Bristol-Myers Squibb Company |
Cell localization signature and combination therapy
|
|
US11458149B1
(en)
|
2019-05-31 |
2022-10-04 |
Ikena Oncology, Inc. |
TEAD inhibitors and uses thereof
|
|
CN114206926B
(zh)
|
2019-06-10 |
2022-06-17 |
山东博安生物技术股份有限公司 |
抗PDL1和TGFβ的双功能融合蛋白及其用途
|
|
WO2020252336A1
(en)
|
2019-06-12 |
2020-12-17 |
Vanderbilt University |
Dibenzylamines as amino acid transport inhibitors
|
|
AU2020291464A1
(en)
|
2019-06-12 |
2022-02-03 |
Vanderbilt University |
Amino acid transport inhibitors and the uses thereof
|
|
US20220307035A1
(en)
*
|
2019-06-12 |
2022-09-29 |
Acurasysbio Co., Ltd. |
Composition for preventing or treating cancer
|
|
US20220220204A1
(en)
*
|
2019-06-12 |
2022-07-14 |
Nanjing GenScript Biotech Co., Ltd. |
Anti-pd-l1/anti-lag-3 multiple antigen binding proteins and methods of use thereof
|
|
JP2022538284A
(ja)
|
2019-06-27 |
2022-09-01 |
ザ ジョージ ワシントン ユニバーシティ, ア コングレッショナリー チャータード ノット-フォー-プロフィット コーポレイション |
Hdac6活性化マクロファージ、その組成物および使用
|
|
KR20220028075A
(ko)
|
2019-07-03 |
2022-03-08 |
스미토모 다이니폰 파마 온콜로지, 인크. |
티로신 키나제 비-수용체 1 (tnk1) 억제제 및 그의 용도
|
|
US20220356255A1
(en)
*
|
2019-07-15 |
2022-11-10 |
Capella Bioscience Ltd |
Anti-pd-l1 antibodies
|
|
AU2020315401B2
(en)
|
2019-07-16 |
2025-05-22 |
The Regents Of The University Of Michigan |
Imidazopyrimidines as EED inhibitors and the use thereof
|
|
CN114269780B
(zh)
|
2019-07-19 |
2024-01-19 |
北京先通生物医药技术有限公司 |
一种新型抗pd-l1抗体及其用途
|
|
WO2021024020A1
(en)
|
2019-08-06 |
2021-02-11 |
Astellas Pharma Inc. |
Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
|
|
CN114641337A
(zh)
|
2019-08-27 |
2022-06-17 |
密歇根大学董事会 |
Cereblon e3连接酶抑制剂
|
|
AR119821A1
(es)
|
2019-08-28 |
2022-01-12 |
Bristol Myers Squibb Co |
Compuestos de piridopirimidinonilo sustituidos útiles como activadores de células t
|
|
CR20220076A
(es)
|
2019-08-30 |
2022-06-24 |
Agenus Inc |
Anticuerpos anti-cd96 y sus métodos de uso
|
|
WO2021048292A1
(en)
|
2019-09-11 |
2021-03-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
JP2022547719A
(ja)
|
2019-09-13 |
2022-11-15 |
ニンバス サターン, インコーポレイテッド |
Hpk1アンタゴニストおよびその使用
|
|
US11655303B2
(en)
|
2019-09-16 |
2023-05-23 |
Surface Oncology, Inc. |
Anti-CD39 antibody compositions and methods
|
|
US11918649B2
(en)
|
2019-09-18 |
2024-03-05 |
Molecular Templates, Inc. |
PD-L1-binding molecules comprising Shiga toxin a subunit scaffolds
|
|
KR20220081977A
(ko)
|
2019-09-18 |
2022-06-16 |
몰레큘러 템플레이츠, 인코퍼레이션. |
시가 독소 a 서브유닛 스캐폴드를 포함하는 pd-l1 결합분자(pd-l1 binding molecules comprising shiga toxin a subunit scaffolds)
|
|
JP2022548881A
(ja)
|
2019-09-18 |
2022-11-22 |
ノバルティス アーゲー |
Entpd2抗体、組合せ療法並びに抗体及び組合せ療法を使用する方法
|
|
TW202124446A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
與entpd2抗體之組合療法
|
|
EP4031575A1
(en)
|
2019-09-19 |
2022-07-27 |
Bristol-Myers Squibb Company |
Antibodies binding to vista at acidic ph
|
|
CN115023267A
(zh)
|
2019-09-19 |
2022-09-06 |
密歇根大学董事会 |
螺环雄激素受体蛋白质降解剂
|
|
KR20220068242A
(ko)
|
2019-09-20 |
2022-05-25 |
트랜스진 |
Hpv 폴리펩티드 및 il-2를 암호화하는 폭스바이러스와 항-pd-l1 항체의 조합
|
|
JP2022549273A
(ja)
|
2019-09-22 |
2022-11-24 |
ブリストル-マイヤーズ スクイブ カンパニー |
Lag-3アンタゴニスト治療のための定量的空間プロファイリング
|
|
JP7739269B2
(ja)
|
2019-09-25 |
2025-09-16 |
ブリストル-マイヤーズ スクイブ カンパニー |
がん療法のための複合バイオマーカー
|
|
TW202521984A
(zh)
|
2019-09-25 |
2025-06-01 |
美商表面腫瘤學有限責任公司 |
抗il-27抗體及其用途
|
|
TWI867053B
(zh)
|
2019-09-26 |
2024-12-21 |
瑞士商諾華公司 |
抗病毒吡唑并吡啶酮化合物
|
|
WO2021058711A2
(en)
|
2019-09-27 |
2021-04-01 |
Glaxosmithkline Intellectual Property Development Limited |
Antigen binding proteins
|
|
EP3800201A1
(en)
|
2019-10-01 |
2021-04-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Cd28h stimulation enhances nk cell killing activities
|
|
AU2020358979A1
(en)
|
2019-10-03 |
2022-04-21 |
Xencor, Inc. |
Targeted IL-12 heterodimeric Fc-fusion proteins
|
|
US20220354811A1
(en)
|
2019-10-03 |
2022-11-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for modulating macrophages polarization
|
|
EP4037710A1
(en)
|
2019-10-04 |
2022-08-10 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and pharmaceutical composition for the treatment of ovarian cancer, breast cancer or pancreatic cancer
|
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
|
EP4045061A4
(en)
|
2019-10-14 |
2024-04-17 |
ARO Biotherapeutics Company |
FIBRONECTIN TYPE III DOMAINS BINDING TO CD137
|
|
WO2021076574A2
(en)
|
2019-10-14 |
2021-04-22 |
Aro Biotherapeutics Company |
Fn3 domain-sirna conjugates and uses thereof
|
|
US12491255B2
(en)
|
2019-10-14 |
2025-12-09 |
Aro Biotherapeutics Company |
EPCAM binding fibronectin type III domains
|
|
CA3157889A1
(en)
|
2019-10-17 |
2021-04-22 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods for diagnosing nasal intestinal type adenocarcinomas
|
|
JP2022553306A
(ja)
|
2019-10-21 |
2022-12-22 |
ノバルティス アーゲー |
Tim-3阻害剤およびその使用
|
|
CN114786679A
(zh)
|
2019-10-21 |
2022-07-22 |
诺华股份有限公司 |
具有维奈托克和tim-3抑制剂的组合疗法
|
|
EP4048795A1
(en)
|
2019-10-23 |
2022-08-31 |
Checkmate Pharmaceuticals, Inc. |
Synthetic rig-i-like receptor agonists
|
|
WO2021079958A1
(ja)
|
2019-10-25 |
2021-04-29 |
第一三共株式会社 |
抗garp抗体と免疫調節剤の組み合わせ
|
|
US20240122938A1
(en)
|
2019-10-29 |
2024-04-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating uveal melanoma
|
|
KR20220092918A
(ko)
|
2019-11-04 |
2022-07-04 |
알렉터 엘엘씨 |
Siglec-9 ecd 융합 분자 및 이의 사용 방법
|
|
WO2021092220A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
WO2021092221A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
CN115942973A
(zh)
|
2019-11-08 |
2023-04-07 |
百时美施贵宝公司 |
用于黑色素瘤的lag-3拮抗剂疗法
|
|
US20220395553A1
(en)
|
2019-11-14 |
2022-12-15 |
Cohbar, Inc. |
Cxcr4 antagonist peptides
|
|
MX2022005839A
(es)
|
2019-11-19 |
2022-06-09 |
Bristol Myers Squibb Co |
Compuestos utiles como inhibidores de la proteina helios.
|
|
WO2021102343A1
(en)
|
2019-11-22 |
2021-05-27 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Solid dose pharmaceutical composition
|
|
CN115151306A
(zh)
|
2019-11-26 |
2022-10-04 |
百时美施贵宝公司 |
(r)-n-(4-氯苯基)-2-((1s,4s)-4-(6-氟喹啉-4-基)环己基)丙酰胺的盐/共晶
|
|
PL4065582T3
(pl)
|
2019-11-26 |
2025-08-18 |
Ikena Oncology, Inc. |
Polimorficzne pochodne karbazolu i ich zastosowania
|
|
CN115023270A
(zh)
|
2019-11-27 |
2022-09-06 |
迈斯特治疗公司 |
使用调节剂产生肿瘤反应性t细胞组合物的方法
|
|
EP4066852A4
(en)
|
2019-11-27 |
2024-05-22 |
NEC Corporation |
PHARMACEUTICAL COMPOSITION
|
|
WO2021127190A1
(en)
|
2019-12-17 |
2021-06-24 |
Kymera Therapeutics, Inc. |
Irak degraders and uses thereof
|
|
US11591332B2
(en)
|
2019-12-17 |
2023-02-28 |
Kymera Therapeutics, Inc. |
IRAK degraders and uses thereof
|
|
WO2021123243A1
(en)
|
2019-12-19 |
2021-06-24 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and vaccine compositions to treat cancers
|
|
US20230089255A1
(en)
|
2019-12-19 |
2023-03-23 |
Bristol-Myers Squibb Company |
Combinations of dgk inhibitors and checkpoint antagonists
|
|
CN115175937A
(zh)
|
2019-12-20 |
2022-10-11 |
诺华股份有限公司 |
用于治疗骨髓纤维化和骨髓增生异常综合征的抗TIM-3抗体MBG453和抗TGF-β抗体NIS793与或不与地西他滨或抗PD-1抗体斯巴达珠单抗的组合
|
|
IL294273A
(en)
|
2019-12-23 |
2022-08-01 |
Bristol Myers Squibb Co |
Substituted heteroaryl compounds are useful as t-cell activators
|
|
AR120823A1
(es)
|
2019-12-23 |
2022-03-23 |
Bristol Myers Squibb Co |
Compuestos bicíclicos sustituidos útiles como activadores de células t
|
|
AU2020415377A1
(en)
|
2019-12-23 |
2022-08-18 |
Bristol-Myers Squibb Company |
Substituted quinazolinyl compounds useful as T cell activators
|
|
AU2020412780A1
(en)
|
2019-12-23 |
2022-07-21 |
Kymera Therapeutics, Inc. |
SMARCA degraders and uses thereof
|
|
EP4081513B1
(en)
|
2019-12-23 |
2024-11-20 |
Bristol-Myers Squibb Company |
Substituted quinolinonyl piperazine compounds useful as t cell activators
|
|
KR20220120624A
(ko)
|
2019-12-23 |
2022-08-30 |
브리스톨-마이어스 스큅 컴퍼니 |
T 세포 활성화제로서 유용한 치환된 피페라진 유도체
|
|
GB2609554B
(en)
|
2020-01-03 |
2025-08-20 |
Marengo Therapeutics Inc |
Anti-TCR antibody molecules and uses thereof
|
|
WO2021138407A2
(en)
|
2020-01-03 |
2021-07-08 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to cd33 and uses thereof
|
|
EP4087874A1
(en)
|
2020-01-06 |
2022-11-16 |
HiFiBiO (HK) Limited |
Anti-tnfr2 antibody and uses thereof
|
|
US20230054718A1
(en)
|
2020-01-07 |
2023-02-23 |
Hifibio (Hk) Limited |
Anti-galectin-9 antibody and uses thereof
|
|
JP7573622B2
(ja)
|
2020-01-10 |
2024-10-25 |
イネイト・テューマー・イミュニティ・インコーポレイテッド |
Nlrp3モジュレーター
|
|
US11981705B2
(en)
|
2020-01-10 |
2024-05-14 |
The Brigham And Women's Hospital, Inc. |
Methods and compositions for delivery of immunotherapy agents across the blood-brain barrier to treat brain cancer
|
|
CN115279771B
(zh)
|
2020-01-15 |
2025-03-21 |
缆图药品公司 |
Map4k1抑制剂
|
|
EP4090770A1
(en)
|
2020-01-17 |
2022-11-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
KR20220128389A
(ko)
|
2020-01-17 |
2022-09-20 |
노파르티스 아게 |
골수이형성 증후군 또는 만성 골수단핵구성 백혈병을 치료하는데 사용하기 위한 tim-3 억제제 및 저메틸화제를 포함하는 조합물
|
|
CA3161513A1
(en)
|
2020-01-28 |
2021-08-05 |
Irwin DAVIDSON |
Antisense oligonucleotide targeting linc00518 for treating melanoma
|
|
WO2021154073A1
(en)
|
2020-01-29 |
2021-08-05 |
Merus N.V. |
Means and method for modulating immune cell engaging effects.
|
|
EP4097130A1
(en)
|
2020-01-30 |
2022-12-07 |
Ona Therapeutics S.L. |
Combination therapy for treatment of cancer and cancer metastasis
|
|
US20230072528A1
(en)
|
2020-02-05 |
2023-03-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for discontinuing a treatment with a tyrosine kinase inhibitor (tki)
|
|
JP2023514152A
(ja)
|
2020-02-06 |
2023-04-05 |
ブリストル-マイヤーズ スクイブ カンパニー |
Il-10およびその使用
|
|
WO2021167964A1
(en)
|
2020-02-18 |
2021-08-26 |
Alector Llc |
Pilra antibodies and methods of use thereof
|
|
IL295990A
(en)
|
2020-02-27 |
2022-11-01 |
Myst Therapeutics Llc |
Methods for in vitro enrichment and expansion of tumor-reactive t cells and preparations related thereto
|
|
TW202146452A
(zh)
|
2020-02-28 |
2021-12-16 |
瑞士商諾華公司 |
結合cd123和cd3之雙特異性抗體的給藥
|
|
EP4110955A1
(en)
|
2020-02-28 |
2023-01-04 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for diagnosing, prognosing and managing treatment of breast cancer
|
|
WO2021174045A1
(en)
|
2020-02-28 |
2021-09-02 |
Bristol-Myers Squibb Company |
Radiolabeled fibronectin based scaffolds and antibodies and theranostic uses thereof
|
|
TW202146393A
(zh)
|
2020-03-03 |
2021-12-16 |
美商皮克醫療公司 |
Eif4e抑制劑及其用途
|
|
US20230089536A1
(en)
|
2020-03-06 |
2023-03-23 |
Celgene Quanticel Research, Inc. |
Combination of an lsd-1 inhibitor and nivolumab for use in treating sclc or sqnsclc
|
|
MX2022011050A
(es)
|
2020-03-06 |
2022-12-15 |
Ona Therapeutics S L |
Anticuerpos anti-cd36 y su uso para tratar cancer.
|
|
EP3878446A1
(en)
|
2020-03-09 |
2021-09-15 |
Universite De Geneve |
Hsd11b1 inhibitors for use in immunotherapy and uses thereof
|
|
WO2021183428A1
(en)
|
2020-03-09 |
2021-09-16 |
Bristol-Myers Squibb Company |
Antibodies to cd40 with enhanced agonist activity
|
|
KR20230005160A
(ko)
|
2020-03-19 |
2023-01-09 |
카이메라 쎄라퓨틱스 인코포레이티드 |
Mdm2 분해제 및 이의 용도
|
|
IL295569A
(en)
|
2020-03-19 |
2022-10-01 |
Arcus Biosciences Inc |
Tetralin and tetrahydroquinoline compounds as inhibitors of hif-2alpha
|
|
TW202140441A
(zh)
|
2020-03-23 |
2021-11-01 |
美商必治妥美雅史谷比公司 |
經取代之側氧基異吲哚啉化合物
|
|
KR20220157446A
(ko)
|
2020-03-23 |
2022-11-29 |
브리스톨-마이어스 스큅 컴퍼니 |
암을 치료하기 위한 항-ccr8 항체
|
|
US20230159573A1
(en)
|
2020-03-26 |
2023-05-25 |
The Regents Of The University Of Michigan |
Small molecule stat protein degraders
|
|
EP4132971A1
(en)
|
2020-04-09 |
2023-02-15 |
Merck Sharp & Dohme LLC |
Affinity matured anti-lap antibodies and uses thereof
|
|
CA3175490A1
(en)
|
2020-04-14 |
2021-10-21 |
Glaxosmithkline Intellectual Property Limited |
Combination treatment for cancer based upon an icos antibody and a pd-l1 antibody tgf-beta-receptor fusion protein
|
|
KR20230037069A
(ko)
|
2020-04-22 |
2023-03-15 |
이오반스 바이오테라퓨틱스, 인크. |
환자-특이적 면역요법을 위해 세포의 제조를 조정하기 위한 시스템 및 방법
|
|
WO2021219807A1
(en)
*
|
2020-04-30 |
2021-11-04 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Pd-l1 variants with improved affinity towards pd-1
|
|
WO2021224215A1
(en)
|
2020-05-05 |
2021-11-11 |
F. Hoffmann-La Roche Ag |
Predicting response to pd-1 axis inhibitors
|
|
AU2021272895A1
(en)
|
2020-05-12 |
2022-09-22 |
Cue Biopharma, Inc. |
Multimeric T-cell modulatory polypeptides and methods of use thereof
|
|
WO2021231732A1
(en)
|
2020-05-15 |
2021-11-18 |
Bristol-Myers Squibb Company |
Antibodies to garp
|
|
EP4157343A2
(en)
|
2020-05-26 |
2023-04-05 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Severe acute respiratory syndrome coronavirus 2 (sars-cov-2) polypeptides and uses thereof for vaccine purposes
|
|
AU2021280245A1
(en)
|
2020-05-26 |
2022-12-08 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cervical cancer by administering a PD-1 inhibitor
|
|
EP4157319A1
(en)
|
2020-05-28 |
2023-04-05 |
Modernatx, Inc. |
Use of mrnas encoding ox40l, il-23 and il-36gamma for treating cancer
|
|
KR20230019152A
(ko)
|
2020-06-02 |
2023-02-07 |
아르커스 바이오사이언시즈 인코포레이티드 |
Tigit에 대한 항체
|
|
TW202210483A
(zh)
|
2020-06-03 |
2022-03-16 |
美商凱麥拉醫療公司 |
Irak降解劑之結晶型
|
|
WO2021247897A1
(en)
|
2020-06-03 |
2021-12-09 |
Kymera Therapeutics, Inc. |
Deuterated irak degraders and uses thereof
|
|
WO2021249969A1
(en)
|
2020-06-10 |
2021-12-16 |
Merck Patent Gmbh |
Combination product for the treatment of cancer diseases
|
|
WO2021258010A1
(en)
|
2020-06-19 |
2021-12-23 |
Gossamer Bio Services, Inc. |
Oxime compounds useful as t cell activators
|
|
TW202214857A
(zh)
|
2020-06-19 |
2022-04-16 |
法商昂席歐公司 |
新型結合核酸分子及其用途
|
|
CA3182346A1
(en)
|
2020-06-23 |
2021-12-30 |
Novartis Ag |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
US20230250173A1
(en)
|
2020-07-01 |
2023-08-10 |
Pfizer Inc. |
Biomarkers for pd-1 axis binding antagonist therapy
|
|
AU2021306613A1
(en)
|
2020-07-07 |
2023-02-02 |
BioNTech SE |
Therapeutic RNA for HPV-positive cancer
|
|
US20230233690A1
(en)
|
2020-07-10 |
2023-07-27 |
The Regents Of The University Of Michigan |
Androgen receptor protein degraders
|
|
US20230257365A1
(en)
|
2020-07-10 |
2023-08-17 |
The Regents Of The University Of Michigan |
Small molecule androgen receptor protein degraders
|
|
WO2022023379A1
(en)
|
2020-07-28 |
2022-02-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for preventing and treating a cancer
|
|
MX2023001217A
(es)
|
2020-07-30 |
2023-03-03 |
Kymera Therapeutics Inc |
Metodos de tratamiento de linfomas mutantes.
|
|
US20230271940A1
(en)
|
2020-08-03 |
2023-08-31 |
Novartis Ag |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
MX2023001707A
(es)
|
2020-08-10 |
2023-05-04 |
Shanghai Xunbaihui Biotechnology Co Ltd |
Composiciones y métodos para el tratamiento de enfermedades autoinmunes y cánceres por direccionamiento al miembro 8 de la superfamilia de inmunoglobulinas.
|
|
MX2023001588A
(es)
|
2020-08-17 |
2023-05-03 |
Bicycletx Ltd |
Conjugados biciclo específicos para nectina-4 y usos de estos.
|
|
MA71214A
(fr)
|
2020-08-26 |
2025-04-30 |
Regeneron Pharmaceuticals, Inc. |
Méthodes de traitement du cancer par administration d'un inhibiteur de pd-1
|
|
WO2022047046A1
(en)
|
2020-08-26 |
2022-03-03 |
Marengo Therapeutics, Inc. |
Methods of detecting trbc1 or trbc2
|
|
KR20230058442A
(ko)
|
2020-08-28 |
2023-05-03 |
브리스톨-마이어스 스큅 컴퍼니 |
간세포성 암종에 대한 lag-3 길항제 요법
|
|
BR112023003553A2
(pt)
|
2020-08-31 |
2023-04-04 |
Bristol Myers Squibb Co |
Assinatura de localização celular e imunoterapia
|
|
CN111808196B
(zh)
*
|
2020-08-31 |
2020-12-29 |
北京百奥赛图基因生物技术有限公司 |
抗pd-1抗体及其用途
|
|
KR20230061499A
(ko)
|
2020-09-03 |
2023-05-08 |
리제너론 파마슈티칼스 인코포레이티드 |
Pd-1 저해제 투여에 의한 암 통증 치료 방법
|
|
EP4211149A4
(en)
|
2020-09-09 |
2024-10-09 |
Cue Biopharma, Inc. |
MULTIMERIC POLYPEPTIDES MODULATING MHC CLASS II T CELLS FOR THE TREATMENT OF TYPE 1 DIABETES MELLITUS (T1D) AND METHODS OF USE THEREOF
|
|
TW202227126A
(zh)
|
2020-09-14 |
2022-07-16 |
德商百靈佳殷格翰國際股份有限公司 |
異源初免加強疫苗
|
|
CN117157314A
(zh)
*
|
2020-09-16 |
2023-12-01 |
苏州逻晟生物医药有限公司 |
Pd-l1抗体、融合蛋白及其用途
|
|
CN111920948B
(zh)
*
|
2020-09-25 |
2021-02-02 |
安可瑞(山西)生物细胞有限公司 |
包含免疫细胞的药物组合物用于治疗癌症
|
|
CN116601140A
(zh)
|
2020-10-02 |
2023-08-15 |
羿尊生物医药股份有限公司 |
用于皮下施用的包含(s)-2-((s)-2-乙酰氨基-3-(1h-吲哚-3-基)丙酰氨基)-6-重氮基-5-氧代己酸异丙酯的冻干组合物及其用途
|
|
US20230374064A1
(en)
|
2020-10-05 |
2023-11-23 |
Bristol-Myers Squibb Company |
Methods for concentrating proteins
|
|
WO2022076596A1
(en)
|
2020-10-06 |
2022-04-14 |
Codiak Biosciences, Inc. |
Extracellular vesicle-aso constructs targeting stat6
|
|
WO2022084531A1
(en)
|
2020-10-23 |
2022-04-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating glioma
|
|
JP2023548051A
(ja)
|
2020-10-23 |
2023-11-15 |
ブリストル-マイヤーズ スクイブ カンパニー |
肺がんのためのlag-3アンタゴニスト療法
|
|
JP2023549678A
(ja)
|
2020-10-28 |
2023-11-29 |
イケナ オンコロジー, インコーポレイテッド |
AHR阻害剤のPDx阻害剤またはドキソルビシンとの組み合わせ
|
|
EP3992208A1
(en)
*
|
2020-11-03 |
2022-05-04 |
Randox Laboratories Ltd |
Anti-pd-l1 vhh antibodies
|
|
US20240025993A1
(en)
|
2020-11-06 |
2024-01-25 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
|
KR20230107260A
(ko)
|
2020-11-12 |
2023-07-14 |
인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) |
Sars-cov-2 스파이크 단백질의 수용체-결합 도메인에 접합되거나 융합된 항체, 및 백신 목적을 위한 이의 용도
|
|
WO2022101463A1
(en)
|
2020-11-16 |
2022-05-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of the last c-terminal residues m31/41 of zikv m ectodomain for triggering apoptotic cell death
|
|
EP4244392A1
(en)
|
2020-11-16 |
2023-09-20 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and compositions for predicting and treating uveal melanoma
|
|
US20230416830A1
(en)
|
2020-11-16 |
2023-12-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating uveal melanoma
|
|
KR20230131189A
(ko)
|
2020-12-02 |
2023-09-12 |
이케나 온콜로지, 인코포레이티드 |
Tead 억제제 및 이의 용도
|
|
WO2022120353A1
(en)
|
2020-12-02 |
2022-06-09 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
WO2022120179A1
(en)
|
2020-12-03 |
2022-06-09 |
Bristol-Myers Squibb Company |
Multi-tumor gene signatures and uses thereof
|
|
TW202237119A
(zh)
|
2020-12-10 |
2022-10-01 |
美商住友製藥腫瘤公司 |
Alk﹘5抑制劑和彼之用途
|
|
EP4262858A1
(en)
|
2020-12-16 |
2023-10-25 |
Molecular Templates, Inc. |
Clinical methods for use of a pd-l1-binding molecule comprising a shiga toxin effector
|
|
JP2024501207A
(ja)
|
2020-12-16 |
2024-01-11 |
ゴッサマー バイオ サービシズ、インコーポレイテッド |
T細胞活性化剤として有用な化合物
|
|
TW202245808A
(zh)
|
2020-12-21 |
2022-12-01 |
德商拜恩迪克公司 |
用於治療癌症之治療性rna
|
|
WO2022135666A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Treatment schedule for cytokine proteins
|
|
WO2022135667A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Therapeutic rna for treating cancer
|
|
EP4566674A3
(en)
|
2020-12-28 |
2025-08-06 |
Bristol-Myers Squibb Company |
Antibody compositions and methods of use thereof
|
|
JP2024501029A
(ja)
|
2020-12-28 |
2024-01-10 |
ブリストル-マイヤーズ スクイブ カンパニー |
Pd1/pd-l1抗体の皮下投与
|
|
JP2024503300A
(ja)
|
2020-12-30 |
2024-01-25 |
カイメラ セラピューティクス, インコーポレイテッド |
Irak分解剤およびそれらの使用
|
|
WO2022148736A1
(en)
|
2021-01-05 |
2022-07-14 |
Transgene |
Vectorization of muc1 t cell engager
|
|
US20250186539A2
(en)
|
2021-01-11 |
2025-06-12 |
Bicycletx Limited |
Methods for treating cancer
|
|
EP4282413A4
(en)
|
2021-01-21 |
2024-12-25 |
Natural Medicine Institute Of Zhejiang Yangshengtang Co., Ltd. |
COMPOSITION AND METHOD FOR TREATING TUMORS
|
|
JP2024505049A
(ja)
|
2021-01-29 |
2024-02-02 |
ノバルティス アーゲー |
抗cd73及び抗entpd2抗体のための投与方式並びにその使用
|
|
CN117098757A
(zh)
|
2021-02-02 |
2023-11-21 |
里米诺生物科学有限公司 |
Gpr84拮抗剂和其用途
|
|
MX2023009059A
(es)
|
2021-02-02 |
2023-09-15 |
Liminal Biosciences Ltd |
Antagonistas de gpr84 y usos de estos.
|
|
US20240139198A1
(en)
|
2021-02-10 |
2024-05-02 |
Curon Biopharmaceutical (Shanghai) Co., Limited |
Method and combination for treating tumors
|
|
WO2022174253A1
(en)
|
2021-02-12 |
2022-08-18 |
Nimbus Saturn, Inc. |
Hpk1 antagonists and uses thereof
|
|
CA3210553A1
(en)
|
2021-02-12 |
2022-08-18 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydroazepine derivatives for the treatment of cancer
|
|
CN116867494A
(zh)
|
2021-02-15 |
2023-10-10 |
凯麦拉医疗公司 |
Irak4降解剂和其用途
|
|
TW202245788A
(zh)
|
2021-02-15 |
2022-12-01 |
美商凱麥拉醫療公司 |
Irak4降解劑及其用途
|
|
AU2022230795B2
(en)
|
2021-03-02 |
2025-02-13 |
Glaxosmithkline Intellectual Property Development Limited |
Substituted pyridines as dnmt1 inhibitors
|
|
US20240166647A1
(en)
|
2021-03-03 |
2024-05-23 |
The Regents Of The University Of Michigan |
Cereblon Ligands
|
|
WO2022187419A1
(en)
|
2021-03-03 |
2022-09-09 |
The Regents Of The University Of Michigan |
Small molecule degraders of androgen receptor
|
|
WO2022187856A1
(en)
|
2021-03-05 |
2022-09-09 |
Nimbus Saturn, Inc. |
Hpk1 antagonists and uses thereof
|
|
CN117677634A
(zh)
|
2021-03-05 |
2024-03-08 |
利达提斯有限公司 |
三聚体多肽及其在治疗癌症中的用途
|
|
WO2022192145A1
(en)
|
2021-03-08 |
2022-09-15 |
Blueprint Medicines Corporation |
Map4k1 inhibitors
|
|
WO2022197641A1
(en)
|
2021-03-15 |
2022-09-22 |
Rapt Therapeutics, Inc. |
1h-pyrazolo[3,4-d]pyrimidin-6-yl-amine derivatives as hematopoietic progenitor kinase 1 (hpk1) modulators and/or inhibitors for the treatment of cancer and other diseases
|
|
WO2022194908A1
(en)
|
2021-03-17 |
2022-09-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
CN117321418A
(zh)
|
2021-03-18 |
2023-12-29 |
诺华股份有限公司 |
癌症生物标志物及其使用方法
|
|
EP4313123A1
(en)
|
2021-03-23 |
2024-02-07 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cancer in immunosuppressed or immunocompromised patients by administering a pd-1 inhibitor
|
|
TW202304506A
(zh)
|
2021-03-25 |
2023-02-01 |
日商安斯泰來製藥公司 |
涉及抗claudin 18.2抗體的組合治療以治療癌症
|
|
US12071442B2
(en)
|
2021-03-29 |
2024-08-27 |
Nimbus Saturn, Inc. |
Substituted pyrrolo[3,4-c]pyridines as HPK1 antagonists
|
|
AU2022246593A1
(en)
|
2021-03-29 |
2023-10-12 |
Juno Therapeutics, Inc. |
Methods for dosing and treatment with a combination of a checkpoint inhibitor therapy and a car t cell therapy
|
|
EP4314060A1
(en)
|
2021-03-31 |
2024-02-07 |
GlaxoSmithKline Intellectual Property Development Limited |
Antigen binding proteins and combinations thereof
|
|
WO2022212876A1
(en)
|
2021-04-02 |
2022-10-06 |
The Regents Of The University Of California |
Antibodies against cleaved cdcp1 and uses thereof
|
|
BR112023020410A2
(pt)
|
2021-04-05 |
2023-11-28 |
Bristol Myers Squibb Co |
Compostos de oxoisoindolina substituída por piridinila para tratamento de câncer
|
|
WO2022216644A1
(en)
|
2021-04-06 |
2022-10-13 |
Bristol-Myers Squibb Company |
Pyridinyl substituted oxoisoindoline compounds
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
EP4320147A4
(en)
|
2021-04-08 |
2025-06-18 |
Marengo Therapeutics, Inc. |
TCR-BINDING MULTIFUNCTIONAL MOLECULES AND USES THEREOF
|
|
JP2024515263A
(ja)
|
2021-04-09 |
2024-04-08 |
オーエスイー・イミュノセラピューティクス |
改善された特性を有する二機能性分子のための新規足場構造
|
|
CA3214952A1
(en)
|
2021-04-09 |
2022-10-13 |
Silvana Marcel LEIT DE MORADEI |
Cbl-b modulators and uses thereof
|
|
US20240182572A1
(en)
|
2021-04-09 |
2024-06-06 |
Ose Immunotherapeutics |
Scaffold for bifunctional molecules comprising pd-1 or cd28 and sirp binding domains
|
|
CA3213079A1
(en)
|
2021-04-13 |
2022-10-20 |
Kristin Lynne ANDREWS |
Amino-substituted heterocycles for treating cancers with egfr mutations
|
|
US20240228659A1
(en)
|
2021-04-14 |
2024-07-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method to improve nk cells cytotoxicity
|
|
JP2024517610A
(ja)
|
2021-04-14 |
2024-04-23 |
アロ・バイオセラピューティクス・カンパニー |
Cd71に結合するフィブロネクチンiii型ドメイン
|
|
EP4323008A1
(en)
|
2021-04-14 |
2024-02-21 |
ARO Biotherapeutics Company |
Fn3 domain-sirna conjugates and uses thereof
|
|
WO2022221866A1
(en)
|
2021-04-16 |
2022-10-20 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
EP4326903A1
(en)
|
2021-04-23 |
2024-02-28 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and compositions for treating cell senescence accumulation related disease
|
|
WO2022236058A1
(en)
|
2021-05-07 |
2022-11-10 |
Kymera Therapeutics, Inc. |
Cdk2 degraders and uses thereof
|
|
EP4334348A1
(en)
|
2021-05-07 |
2024-03-13 |
Surface Oncology, LLC |
Anti-il-27 antibodies and uses thereof
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
WO2022243378A1
(en)
|
2021-05-18 |
2022-11-24 |
Kymab Limited |
Uses of anti-icos antibodies
|
|
WO2022246177A1
(en)
|
2021-05-21 |
2022-11-24 |
Arcus Biosciences, Inc. |
Axl compounds
|
|
CN117396222A
(zh)
|
2021-05-21 |
2024-01-12 |
天津立博美华基因科技有限责任公司 |
药物组合及其用途
|
|
JP2024521712A
(ja)
|
2021-05-21 |
2024-06-04 |
アーカス バイオサイエンシーズ,インコーポレーテッド |
Axl阻害化合物
|
|
CA3218786A1
(en)
|
2021-05-25 |
2022-12-01 |
Lifei HOU |
C-x-c motif chemokine receptor 6 (cxcr6) binding molecules, and methods of using the same
|
|
CA3220191A1
(en)
|
2021-05-26 |
2022-12-01 |
Tania Crombet Ramos |
Use of therapeutic compositions for the treatment of patients with tumours of epithelial origin
|
|
GB202107994D0
(en)
|
2021-06-04 |
2021-07-21 |
Kymab Ltd |
Treatment of cancer
|
|
CA3218692A1
(en)
|
2021-06-04 |
2022-12-08 |
Boehringer Ingelheim International Gmbh |
Anti-sirp-alpha antibodies
|
|
US20240316005A1
(en)
|
2021-07-05 |
2024-09-26 |
Institut National de la Santé et de la Recherche Médicale |
Gene signatures for predicting survival time in patients suffering from renal cell carcinoma
|
|
JP2024525758A
(ja)
|
2021-07-13 |
2024-07-12 |
ビオンテック・ソシエタス・エウロパエア |
がんのための併用療法におけるcd40およびcd137に対する多重特異性結合剤
|
|
AR126442A1
(es)
|
2021-07-14 |
2023-10-11 |
Blueprint Medicines Corp |
Inhibidores de map4k1
|
|
AR126453A1
(es)
|
2021-07-15 |
2023-10-11 |
Blueprint Medicines Corp |
Inhibidores de map4k1
|
|
EP4373505A1
(en)
|
2021-07-19 |
2024-05-29 |
Regeneron Pharmaceuticals, Inc. |
Combination of checkpoint inhibitors and an oncolytic virus for treating cancer
|
|
US20250206836A1
(en)
|
2021-07-30 |
2025-06-26 |
ONA Therapeutics S.L. |
Anti-cd36 antibodies and their use to treat cancer
|
|
CN118103368A
(zh)
|
2021-08-25 |
2024-05-28 |
皮克医疗公司 |
Eif4e抑制剂及其用途
|
|
JP2024532276A
(ja)
|
2021-08-25 |
2024-09-05 |
ピク セラピューティクス, インコーポレイテッド |
eIF4E阻害剤及びその使用
|
|
IL310773A
(en)
|
2021-09-02 |
2024-04-01 |
Deutsches Krebsforschungszentrum Stiftung Des ?Ffentlichen Rechts |
Anti-CECAM6 antibodies with reduced side effects
|
|
EP4399206A1
(en)
|
2021-09-08 |
2024-07-17 |
Redona Therapeutics, Inc. |
Papd5 and/or papd7 inhibiting 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivatives
|
|
WO2023051926A1
(en)
|
2021-09-30 |
2023-04-06 |
BioNTech SE |
Treatment involving non-immunogenic rna for antigen vaccination and pd-1 axis binding antagonists
|
|
TW202333802A
(zh)
|
2021-10-11 |
2023-09-01 |
德商拜恩迪克公司 |
用於肺癌之治療性rna(二)
|
|
EP4423249A1
(en)
|
2021-10-28 |
2024-09-04 |
Lyell Immunopharma, Inc. |
Methods for culturing immune cells
|
|
AU2022378630A1
(en)
|
2021-10-29 |
2024-05-09 |
Kymera Therapeutics, Inc. |
Irak4 degraders and synthesis thereof
|
|
KR20240099362A
(ko)
|
2021-10-29 |
2024-06-28 |
브리스톨-마이어스 스큅 컴퍼니 |
혈액암에 대한 lag-3 길항제 요법
|
|
JP2024541933A
(ja)
|
2021-11-02 |
2024-11-13 |
ファイザー・インク |
抗gdf15抗体を使用してミトコンドリア筋症を処置する方法
|
|
WO2023078900A1
(en)
|
2021-11-03 |
2023-05-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating triple negative breast cancer (tnbc)
|
|
WO2023083439A1
(en)
|
2021-11-09 |
2023-05-19 |
BioNTech SE |
Tlr7 agonist and combinations for cancer treatment
|
|
EP4433504A1
(en)
|
2021-11-17 |
2024-09-25 |
Institut National de la Santé et de la Recherche Médicale |
Universal sarbecovirus vaccines
|
|
CA3240558A1
(en)
|
2021-12-16 |
2023-06-22 |
Valerio Therapeutics |
New conjugated nucleic acid molecules and their uses
|
|
WO2023114984A1
(en)
|
2021-12-17 |
2023-06-22 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
US20250041261A1
(en)
|
2021-12-21 |
2025-02-06 |
Institut National de la Santé et de la Recherche Médicale |
Methods and compositions for treating melanoma
|
|
WO2023122778A1
(en)
|
2021-12-22 |
2023-06-29 |
Gossamer Bio Services, Inc. |
Pyridazinone derivatives useful as t cell activators
|
|
WO2023122777A1
(en)
|
2021-12-22 |
2023-06-29 |
Gossamer Bio Services, Inc. |
Oxime derivatives useful as t cell activators
|
|
WO2023122772A1
(en)
|
2021-12-22 |
2023-06-29 |
Gossamer Bio Services, Inc. |
Oxime derivatives useful as t cell activators
|
|
WO2023130081A1
(en)
|
2021-12-30 |
2023-07-06 |
Neoimmunetech, Inc. |
Method of treating a tumor with a combination of il-7 protein and vegf antagonist
|
|
JP2025503962A
(ja)
|
2022-01-26 |
2025-02-06 |
ブリストル-マイヤーズ スクイブ カンパニー |
肝細胞がんのための併用療法
|
|
JP2025504059A
(ja)
|
2022-01-31 |
2025-02-06 |
カイメラ セラピューティクス, インコーポレイテッド |
Irakデグレーダー及びその使用
|
|
WO2023150186A1
(en)
|
2022-02-01 |
2023-08-10 |
Arvinas Operations, Inc. |
Dgk targeting compounds and uses thereof
|
|
EP4479388A1
(en)
|
2022-02-14 |
2024-12-25 |
Gilead Sciences, Inc. |
Antiviral naphthyridinone compounds
|
|
WO2023154799A1
(en)
|
2022-02-14 |
2023-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Combination immunotherapy for treating cancer
|
|
JP2025506696A
(ja)
|
2022-02-17 |
2025-03-13 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
がんを処置するためのチェックポイント阻害剤と腫瘍溶解性ウイルスの組合せ
|
|
US20250179174A1
(en)
|
2022-02-25 |
2025-06-05 |
Bristol-Myers Squibb Company |
Combination therapy for colorectal carcinoma
|
|
MX2024010773A
(es)
|
2022-03-03 |
2024-09-10 |
Pfizer |
Anticuerpos multiespecificos y usos de estos.
|
|
KR20230130911A
(ko)
|
2022-03-04 |
2023-09-12 |
주식회사 온코인사이트 |
암 예방 또는 치료를 위한 병용 투여용 약학 조성물
|
|
WO2023168404A1
(en)
|
2022-03-04 |
2023-09-07 |
Bristol-Myers Squibb Company |
Methods of treating a tumor
|
|
AU2023230110A1
(en)
|
2022-03-08 |
2024-10-24 |
Alentis Therapeutics Ag |
Use of anti-claudin-1 antibodies to increase t cell availability
|
|
WO2023173057A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
WO2023173053A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
WO2023174210A1
(en)
|
2022-03-14 |
2023-09-21 |
Laekna Limited |
Combination treatment for cancer
|
|
EP4493195A1
(en)
|
2022-03-15 |
2025-01-22 |
Compugen Ltd. |
Il-18bp antagonist antibodies and their use in monotherapy and combination therapy in the treatment of cancer
|
|
JPWO2023176881A1
(cg-RX-API-DMAC7.html)
|
2022-03-16 |
2023-09-21 |
|
|
|
JP2025509749A
(ja)
|
2022-03-18 |
2025-04-11 |
ブリストル-マイヤーズ スクイブ カンパニー |
ポリペプチドの単離方法
|
|
WO2023192478A1
(en)
|
2022-04-01 |
2023-10-05 |
Bristol-Myers Squibb Company |
Combination therapy with anti-il-8 antibodies and anti-pd-1 antibodies for treating cancer
|
|
WO2023196987A1
(en)
|
2022-04-07 |
2023-10-12 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
WO2023196988A1
(en)
|
2022-04-07 |
2023-10-12 |
Modernatx, Inc. |
Methods of use of mrnas encoding il-12
|
|
WO2023196964A1
(en)
|
2022-04-08 |
2023-10-12 |
Bristol-Myers Squibb Company |
Machine learning identification, classification, and quantification of tertiary lymphoid structures
|
|
EP4507704A1
(en)
|
2022-04-15 |
2025-02-19 |
Iovance Biotherapeutics, Inc. |
Til expansion processes using specific cytokine combinations and/or akti treatment
|
|
WO2023211889A1
(en)
|
2022-04-25 |
2023-11-02 |
Ikena Oncology, Inc. |
Polymorphic compounds and uses thereof
|
|
WO2023213763A1
(en)
*
|
2022-05-02 |
2023-11-09 |
Transgene |
Poxvirus encoding a binding agent comprising an anti- pd-l1 sdab
|
|
WO2023213764A1
(en)
*
|
2022-05-02 |
2023-11-09 |
Transgene |
Fusion polypeptide comprising an anti-pd-l1 sdab and a member of the tnfsf
|
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
|
US20250340641A1
(en)
|
2022-05-18 |
2025-11-06 |
Kymab Limited |
Uses of anti-icos antibodies
|
|
CA3256230A1
(en)
|
2022-05-24 |
2023-11-30 |
Daiichi Sankyo Company, Limited |
DOSAGE REGIMEN OF AN ANTI-CDH6 ANTIBODY-DRUG CONJUGATE
|
|
CN119768393A
(zh)
|
2022-05-25 |
2025-04-04 |
医肯纳肿瘤学公司 |
Mek抑制剂和其用途
|
|
US20250332252A1
(en)
|
2022-06-02 |
2025-10-30 |
Bristol-Myers Squibb Company |
Antibody compositions and methods of use thereof
|
|
CN119923267A
(zh)
|
2022-07-27 |
2025-05-02 |
阿斯利康(瑞典)有限公司 |
表达白介素-12的重组病毒与pd-1/pd-l1抑制剂的组合
|
|
TW202412859A
(zh)
|
2022-07-28 |
2024-04-01 |
英商阿斯特捷利康英國股份有限公司 |
抗體-藥物結合物及雙特異性檢查點抑制劑之組合
|
|
KR20250057800A
(ko)
|
2022-08-02 |
2025-04-29 |
리미널 바이오사이언시스 리미티드 |
헤테로아릴 카복스아마이드 및 관련 gpr84 길항제 및 이의 용도
|
|
IL318576A
(en)
|
2022-08-02 |
2025-03-01 |
Liminal Biosciences Ltd |
Pyridoxine-substituted GPR84 antagonists and their uses
|
|
WO2024028364A1
(en)
|
2022-08-02 |
2024-02-08 |
Liminal Biosciences Limited |
Aryl-triazolyl and related gpr84 antagonists and uses thereof
|
|
EP4568950A1
(en)
|
2022-08-08 |
2025-06-18 |
Bristol-Myers Squibb Company |
Substituted tetrazolyl compounds useful as t cell activators
|
|
WO2024036101A1
(en)
|
2022-08-09 |
2024-02-15 |
Bristol-Myers Squibb Company |
Tertiary amine substituted bicyclic compounds useful as t cell activators
|
|
WO2024033400A1
(en)
|
2022-08-10 |
2024-02-15 |
Institut National de la Santé et de la Recherche Médicale |
Sk2 inhibitor for the treatment of pancreatic cancer
|
|
WO2024033399A1
(en)
|
2022-08-10 |
2024-02-15 |
Institut National de la Santé et de la Recherche Médicale |
Sigmar1 ligand for the treatment of pancreatic cancer
|
|
WO2024033458A1
(en)
|
2022-08-11 |
2024-02-15 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydroazepine derivatives
|
|
JP2025526727A
(ja)
|
2022-08-11 |
2025-08-15 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
二環式テトラヒドロチアゼピン誘導体
|
|
CN119768401A
(zh)
|
2022-08-11 |
2025-04-04 |
豪夫迈·罗氏有限公司 |
双环四氢硫氮杂䓬衍生物
|
|
EP4583860A1
(en)
|
2022-09-06 |
2025-07-16 |
Institut National de la Santé et de la Recherche Médicale |
Inhibitors of the ceramide metabolic pathway for overcoming immunotherapy resistance in cancer
|
|
WO2024054992A1
(en)
|
2022-09-09 |
2024-03-14 |
Bristol-Myers Squibb Company |
Methods of separating chelator
|
|
WO2024056716A1
(en)
|
2022-09-14 |
2024-03-21 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical compositions for the treatment of dilated cardiomyopathy
|
|
WO2024069009A1
(en)
|
2022-09-30 |
2024-04-04 |
Alentis Therapeutics Ag |
Treatment of drug-resistant hepatocellular carcinoma
|
|
EP4606384A1
(en)
|
2022-10-19 |
2025-08-27 |
Astellas Pharma, Inc. |
Use of anti-cldn4-anti-cd137 bispecific antibody combined with pd-1 signal inhibitor for cancer treatment
|
|
WO2024084034A1
(en)
|
2022-10-21 |
2024-04-25 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical compositions for the treatment of osteoarthritis
|
|
KR20250099224A
(ko)
|
2022-11-01 |
2025-07-01 |
하이델베르크 파마 리서치 게엠베하 |
항-gucy2c 항체 및 이의 용도
|
|
WO2024097328A1
(en)
|
2022-11-03 |
2024-05-10 |
Incyte Corporation |
Combination therapies comprising an anti-gitr antibody for treating cancers
|
|
EP4615480A1
(en)
|
2022-11-07 |
2025-09-17 |
Alector LLC |
Uses of siglec-9 ecd fusion molecules in cancer treatment
|
|
KR20250089492A
(ko)
|
2022-11-07 |
2025-06-18 |
네오이뮨텍, 인코퍼레이티드 |
비메틸화된 mgmt 프로모터를 갖는 종양의 치료 방법
|
|
EP4623072A2
(en)
|
2022-11-21 |
2025-10-01 |
Iovance Biotherapeutics, Inc. |
Two-dimensional processes for the expansion of tumor infiltrating lymphocytes and therapies therefrom
|
|
WO2024112894A1
(en)
|
2022-11-22 |
2024-05-30 |
PIC Therapeutics, Inc. |
Eif4e inhibitors and uses thereof
|
|
WO2024115725A1
(en)
|
2022-12-01 |
2024-06-06 |
BioNTech SE |
Multispecific antibody against cd40 and cd137 in combination therapy with anti-pd1 ab and chemotherapy
|
|
KR20250120305A
(ko)
|
2022-12-14 |
2025-08-08 |
아스텔라스 파마 유럽 비.브이. |
Cldn18.2 및 cd3에 결합하는 2중 특이성 결합제와 면역 체크포인트 저해제를 수반한 조합 요법
|
|
KR20250123912A
(ko)
|
2022-12-21 |
2025-08-18 |
브리스톨-마이어스 스큅 컴퍼니 |
폐암에 대한 병용 요법
|
|
WO2024137865A1
(en)
|
2022-12-22 |
2024-06-27 |
Gossamer Bio Services, Inc. |
Compounds useful as t cell activators
|
|
CN116077645A
(zh)
*
|
2022-12-28 |
2023-05-09 |
广州誉衡生物科技有限公司 |
抗-pd-1抗体及其在制备治疗非小细胞肺癌患者的药物中的用途
|
|
WO2024151885A1
(en)
|
2023-01-13 |
2024-07-18 |
Iovance Biotherapeutics, Inc. |
Use of til as maintenance therapy for nsclc patients who achieved pr/cr after prior therapy
|
|
EP4658310A1
(en)
|
2023-01-30 |
2025-12-10 |
Kymab Limited |
Antibodies
|
|
EP4658687A1
(en)
|
2023-01-31 |
2025-12-10 |
University of Rochester |
Immune checkpoint blockade therapy for treating staphylococcus aureus infections
|
|
WO2024184417A1
(en)
|
2023-03-07 |
2024-09-12 |
Photocure Asa |
Therapy for bladder cancer
|
|
WO2024192051A1
(en)
|
2023-03-13 |
2024-09-19 |
Turnstone Biologics Corp. |
Composition of selected tumor infiltrating lymphocytes and related methods of producing and using the same
|
|
WO2024196952A1
(en)
|
2023-03-20 |
2024-09-26 |
Bristol-Myers Squibb Company |
Tumor subtype assessment for cancer therapy
|
|
WO2024200571A1
(en)
|
2023-03-28 |
2024-10-03 |
Institut National de la Santé et de la Recherche Médicale |
Method for discriminating mono-immunotherapy from combined immunotherapy in cancers
|
|
CN120917143A
(zh)
|
2023-03-29 |
2025-11-07 |
第一三共株式会社 |
抗cd25抗体及抗cd25抗体-药物偶联物
|
|
WO2024216028A1
(en)
|
2023-04-12 |
2024-10-17 |
Agenus Inc. |
Methods of treating cancer using an anti-ctla4 antibody and an enpp1 inhibitor
|
|
WO2024213767A1
(en)
|
2023-04-14 |
2024-10-17 |
Institut National de la Santé et de la Recherche Médicale |
Engraftment of mesenchymal stromal cells engineered to stimulate immune infiltration in tumors
|
|
WO2024223299A2
(en)
|
2023-04-26 |
2024-10-31 |
Isa Pharmaceuticals B.V. |
Methods of treating cancer by administering immunogenic compositions and a pd-1 inhibitor
|
|
WO2024228167A1
(en)
|
2023-05-03 |
2024-11-07 |
Iox Therapeutics Inc. |
Inkt cell modulator liposomal compositions and methods of use
|
|
CN121079326A
(zh)
|
2023-05-04 |
2025-12-05 |
诺瓦森塔股份有限公司 |
抗cd161抗体及其使用方法
|
|
AR132623A1
(es)
*
|
2023-05-08 |
2025-07-16 |
Hoffmann La Roche |
PROTEÍNAS DE FUSIÓN DE INTERFERÓN a DIRIGIDAS Y MÉTODOS DE USO
|
|
KR20250019700A
(ko)
|
2023-05-08 |
2025-02-10 |
브리스톨-마이어스 스큅 컴퍼니 |
치환된 페닐 옥사졸론 화합물
|
|
WO2024231384A1
(en)
|
2023-05-10 |
2024-11-14 |
Institut National de la Santé et de la Recherche Médicale |
Compositions for treating senescence related disease
|
|
TW202509014A
(zh)
|
2023-05-10 |
2025-03-01 |
美商纜圖藥品公司 |
GSK3α抑制劑及其使用方法
|
|
WO2024245951A1
(en)
|
2023-05-26 |
2024-12-05 |
Institut National de la Santé et de la Recherche Médicale |
Combination of slc8a1 inhibitor and mitochondria-targeted antioxidant for treating melanoma
|
|
WO2024249540A1
(en)
|
2023-05-31 |
2024-12-05 |
Bristol-Myers Squibb Company |
Substituted oxazolone compound for decreasing levels of ikzf1-4 proteins
|
|
WO2024254227A1
(en)
|
2023-06-07 |
2024-12-12 |
Bristol-Myers Squibb Company |
Spirocyclic substituted oxoisoindolinyl piperidine-2,6-dione compound
|
|
WO2024256635A1
(en)
|
2023-06-15 |
2024-12-19 |
Institut National de la Santé et de la Recherche Médicale |
Dpm1 inhibitor for treating cancer
|
|
WO2024261302A1
(en)
|
2023-06-22 |
2024-12-26 |
Institut National de la Santé et de la Recherche Médicale |
Nlrp3 inhibitors, pak1/2 inhibitors and/or caspase 1 inhibitors for use in the treatment of rac2 monogenic disorders
|
|
EP4615455A2
(en)
|
2023-06-23 |
2025-09-17 |
Kymera Therapeutics, Inc. |
Irak degraders and uses thereof
|
|
WO2024263853A1
(en)
|
2023-06-23 |
2024-12-26 |
Bristol-Myers Squibb Company |
Substituted oxoisoindolinyl piperidine-2,6-dione compound as anticancer agent
|
|
WO2025003193A1
(en)
|
2023-06-26 |
2025-01-02 |
Institut National de la Santé et de la Recherche Médicale |
Sertraline and indatraline for disrupting intracellular cholesterol trafficking and subsequently inducing lysosomal damage and anti-tumor immunity
|
|
TW202515608A
(zh)
|
2023-06-26 |
2025-04-16 |
以色列商坎布根有限公司 |
Il—18bp拮抗抗體及其於癌症治療之單一療法及組合療法的用途
|
|
WO2025006811A1
(en)
|
2023-06-27 |
2025-01-02 |
Lyell Immunopharma, Inc. |
Methods for culturing immune cells
|
|
WO2025012417A1
(en)
|
2023-07-13 |
2025-01-16 |
Institut National de la Santé et de la Recherche Médicale |
Anti-neurotensin long fragment and anti-neuromedin n long fragment antibodies and uses thereof
|
|
WO2025030002A2
(en)
|
2023-08-02 |
2025-02-06 |
Arvinas Operations, Inc. |
Dgk targeting compounds and uses thereof
|
|
WO2025031923A1
(en)
|
2023-08-04 |
2025-02-13 |
Sanofi |
Imidazo[4,5-d]pyridazine compounds and conjugates thereof, their preparation, and their therapeutic applications
|
|
WO2025038763A1
(en)
|
2023-08-15 |
2025-02-20 |
Bristol-Myers Squibb Company |
Ceramic hydroxyapatite chromatography flow through method
|
|
WO2025064197A1
(en)
|
2023-09-02 |
2025-03-27 |
Bristol-Myers Squibb Company |
Substituted azetidinyl oxoisoindolinyl piperidine-2,6-dione compounds
|
|
EP4568957A1
(en)
|
2023-09-02 |
2025-06-18 |
Bristol-Myers Squibb Company |
Substituted phenyl oxooxazolyl piperidine dione compounds
|
|
AR133800A1
(es)
|
2023-09-13 |
2025-11-05 |
Bristol Myers Squibb Co |
Compuestos de oxoisoindolinil piperidina-2,6-diona sustituida
|
|
WO2025056180A1
(en)
|
2023-09-15 |
2025-03-20 |
BioNTech SE |
Methods of treatment using agents binding to epcam and cd137 in combination with pd-1 axis binding antagonists
|
|
WO2025073765A1
(en)
|
2023-10-03 |
2025-04-10 |
Institut National de la Santé et de la Recherche Médicale |
Methods of prognosis and treatment of patients suffering from melanoma
|
|
US20250114468A1
(en)
|
2023-10-09 |
2025-04-10 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cancer with a combination of a pd1 inhibitor and a targeted immunocytokine
|
|
WO2025080865A1
(en)
|
2023-10-11 |
2025-04-17 |
Turnstone Biologics Corp. |
Combination of tumor infiltrating lymphocytes (til) and low dose radiation
|
|
WO2025078632A1
(en)
|
2023-10-12 |
2025-04-17 |
Institut National de la Santé et de la Recherche Médicale |
Methods of prognosis and treatment of patients suffering from cancer
|
|
WO2025096638A2
(en)
|
2023-10-30 |
2025-05-08 |
Turnstone Biologics Corp. |
Genetically modified tumor infilitrating lymphocytes and methods of producing and using the same
|
|
WO2025096489A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
US20250145590A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025096494A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025096490A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025096505A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025096488A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025096487A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025106278A1
(en)
|
2023-11-17 |
2025-05-22 |
Mersana Therapeutics, Inc. |
Treatment of cancer using b7-h4-targeted antibody-drug conjugates
|
|
WO2025121445A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2025120866A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2025120867A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and anti-vegfr2 antibodies
|
|
WO2025132479A1
(en)
|
2023-12-18 |
2025-06-26 |
Institut National de la Santé et de la Recherche Médicale |
Flt3 inhibitor for modulating macrophages polarization
|
|
WO2025133389A1
(en)
|
2023-12-22 |
2025-06-26 |
Numab Therapeutics AG |
Antibody binding domains having specificity for lilrb2
|
|
WO2025132770A1
(en)
|
2023-12-22 |
2025-06-26 |
Institut National de la Santé et de la Recherche Médicale |
Affitins for the treatment of cancer
|
|
US20250215087A1
(en)
|
2023-12-29 |
2025-07-03 |
Bristol-Myers Squibb Company |
Combination therapy of kras inhibitor and treg depleting agent
|
|
WO2025151487A2
(en)
|
2024-01-08 |
2025-07-17 |
Regents Of The University Of Michigan |
Small-molecule inhibitors of adar1
|
|
WO2025184208A1
(en)
|
2024-02-27 |
2025-09-04 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibodies and uses thereof
|
|
EP4658320A1
(en)
|
2024-02-27 |
2025-12-10 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibody drug conjugates
|
|
CN118077649B
(zh)
*
|
2024-02-29 |
2024-09-10 |
复旦大学附属中山医院 |
一种免疫检查点抑制剂构建动脉粥样硬化小鼠模型的方法
|
|
US20250361297A1
(en)
|
2024-03-12 |
2025-11-27 |
Adaptam Therapeutics, S.L. |
Anti- siglec-15 binding molecules and methods of use
|
|
WO2025210123A1
(en)
|
2024-04-03 |
2025-10-09 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical composition for treating cancers
|
|
WO2025210175A1
(en)
|
2024-04-04 |
2025-10-09 |
Centre National De La Recherche Scientifique |
Mutant csf-1r extracellular domain fusion molecules and therapeutic uses thereof
|
|
WO2025213154A1
(en)
|
2024-04-05 |
2025-10-09 |
Amgen Inc. |
Gastrointestinal cancer treatments using mta-cooperative prmt5 inhibitors
|
|
WO2025219330A1
(en)
|
2024-04-15 |
2025-10-23 |
Institut National de la Santé et de la Recherche Médicale |
Detection of ppix for use in methods for melanoma ferroptosis sensitivity and targeted therapy resistance prediction
|
|
WO2025226767A1
(en)
|
2024-04-24 |
2025-10-30 |
Bristol-Myers Squibb Company |
Substituted 3-(5-(6-aminopyridin-2-yl)-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione compounds for use in the treatment of cancer
|
|
WO2025228998A1
(en)
|
2024-04-30 |
2025-11-06 |
Institut National de la Santé et de la Recherche Médicale |
Use of hdac4 inhibitors for the treatment of melanoma
|
|
WO2025233867A1
(en)
|
2024-05-10 |
2025-11-13 |
Adaptam Therapeutics, S.L. |
Anti-siglec-9 antibodies and uses thereof
|
|
WO2025232879A1
(en)
|
2024-05-10 |
2025-11-13 |
Cytocares (Shanghai) Inc. |
Anti-lilrb2 monospecific and bispecific antibody constructs and uses thereof
|
|
WO2025245489A1
(en)
|
2024-05-24 |
2025-11-27 |
Bristol-Myers Squibb Company |
Treatment of tumors in subjects having fgl-1 positive samples
|
|
WO2025247829A1
(en)
|
2024-05-27 |
2025-12-04 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical composition for treating prostate cancer
|
|
WO2025254987A1
(en)
|
2024-06-03 |
2025-12-11 |
Alector Llc |
Siglec-9 ecd fusion molecule variants and methods of use thereof
|