SG11201504558TA - Methods for high throughput receptor:ligand identification - Google Patents
Methods for high throughput receptor:ligand identificationInfo
- Publication number
- SG11201504558TA SG11201504558TA SG11201504558TA SG11201504558TA SG11201504558TA SG 11201504558T A SG11201504558T A SG 11201504558TA SG 11201504558T A SG11201504558T A SG 11201504558TA SG 11201504558T A SG11201504558T A SG 11201504558TA SG 11201504558T A SG11201504558T A SG 11201504558TA
- Authority
- SG
- Singapore
- Prior art keywords
- methods
- high throughput
- ligand identification
- receptor
- throughput receptor
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/06—Methods of screening libraries by measuring effects on living organisms, tissues or cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261735791P | 2012-12-11 | 2012-12-11 | |
US201361833588P | 2013-06-11 | 2013-06-11 | |
PCT/US2013/073275 WO2014093118A1 (en) | 2012-12-11 | 2013-12-05 | Methods for high throughput receptor:ligand identification |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201504558TA true SG11201504558TA (en) | 2015-07-30 |
Family
ID=50934838
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201504558TA SG11201504558TA (en) | 2012-12-11 | 2013-12-05 | Methods for high throughput receptor:ligand identification |
SG10201808463RA SG10201808463RA (en) | 2012-12-11 | 2013-12-05 | Methods for high throughput receptor:ligand identification |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201808463RA SG10201808463RA (en) | 2012-12-11 | 2013-12-05 | Methods for high throughput receptor:ligand identification |
Country Status (12)
Country | Link |
---|---|
US (2) | US10048271B2 (en) |
EP (2) | EP3640375A3 (en) |
JP (2) | JP2016500255A (en) |
KR (1) | KR102208505B1 (en) |
CN (2) | CN109324190A (en) |
AU (2) | AU2013359907B2 (en) |
BR (1) | BR112015013557B1 (en) |
CA (1) | CA2894511C (en) |
HK (1) | HK1218144A1 (en) |
IL (2) | IL239096B (en) |
SG (2) | SG11201504558TA (en) |
WO (1) | WO2014093118A1 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2894511C (en) | 2012-12-11 | 2021-12-07 | Albert Einstein College Of Medicine Of Yeshiva University | Methods for high throughput receptor:ligand identification |
CN106471122B (en) | 2014-07-07 | 2020-07-03 | 阿斯特瑞格诊断公司 | Phenotypic identification and in situ genotyping of libraries of genetically distinct cells |
KR20190019068A (en) | 2016-05-18 | 2019-02-26 | 큐 바이오파마, 인크. | T-cell modulated multimeric polypeptides and methods for their use |
EP3458095A4 (en) | 2016-05-18 | 2019-11-27 | Albert Einstein College of Medicine | Variant pd-l1 polypeptides, t-cell modulatory multimeric polypeptides, and methods of use thereof |
JP7019171B2 (en) * | 2016-11-24 | 2022-02-15 | 国立研究開発法人物質・材料研究機構 | A method for measuring cell-cell interactions due to the binding of molecules existing on the cell surface |
WO2018111941A1 (en) * | 2016-12-12 | 2018-06-21 | 13.8, Inc. | Compositions of high affinity reagents and methods of use thereof |
EP3558339B1 (en) | 2016-12-22 | 2024-01-24 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
EP3565829A4 (en) | 2017-01-09 | 2021-01-27 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
IL269000B2 (en) | 2017-03-15 | 2024-06-01 | Cue Biopharma Inc | Methods for modulating an immune response |
CN111315768A (en) | 2017-09-07 | 2020-06-19 | 库尔生物制药有限公司 | T cell regulatory multimeric polypeptides with conjugation sites and methods of use thereof |
WO2019139896A1 (en) | 2018-01-09 | 2019-07-18 | Cue Biopharma, Inc. | Multimeric t-cell modulatory polypeptides and methods of use thereof |
KR20230009872A (en) | 2020-05-12 | 2023-01-17 | 큐 바이오파마, 인크. | Multimeric T-Cell Regulatory Polypeptides and Methods of Use Thereof |
Family Cites Families (86)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5635363A (en) | 1995-02-28 | 1997-06-03 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for the detection, quantitation and purification of antigen-specific T cells |
US5869270A (en) | 1996-01-31 | 1999-02-09 | Sunol Molecular Corporation | Single chain MHC complexes and uses thereof |
US6211342B1 (en) | 1996-07-18 | 2001-04-03 | Children's Hospital Medical Center | Multivalent MHC complex peptide fusion protein complex for stimulating specific T cell function |
US20050003431A1 (en) | 1996-08-16 | 2005-01-06 | Wucherpfennig Kai W. | Monovalent, multivalent, and multimeric MHC binding domain fusion proteins and conjugates, and uses therefor |
WO1998035981A1 (en) | 1997-02-13 | 1998-08-20 | The Regents Of The University Of California | Prevention and treatment of hepatocellular cancer |
US7098306B2 (en) | 1997-02-13 | 2006-08-29 | The Regents Of The University Of California | Method and compositions for treating hepatocellular cancer |
US6268411B1 (en) | 1997-09-11 | 2001-07-31 | The Johns Hopkins University | Use of multivalent chimeric peptide-loaded, MHC/ig molecules to detect, activate or suppress antigen-specific T cell-dependent immune responses |
US20030007978A1 (en) | 1997-09-16 | 2003-01-09 | Burrows Gregory G. | Recombinant MHC molecules useful for manipulation of antigen-specific T-cells |
US6696304B1 (en) | 1999-02-24 | 2004-02-24 | Luminex Corporation | Particulate solid phase immobilized protein quantitation |
US7446189B1 (en) | 1999-04-30 | 2008-11-04 | Institut De Recherches Cliniques De Montreal | Nucleic acids encoding mutant human CD80 and compositions comprising the same |
US20020006664A1 (en) | 1999-09-17 | 2002-01-17 | Sabatini David M. | Arrayed transfection method and uses related thereto |
EP1287363A2 (en) | 2000-05-25 | 2003-03-05 | Sunol Molecular Corporation | Modulation of t-cell receptor interactions |
US20020122820A1 (en) | 2001-01-16 | 2002-09-05 | Hildebrand William H. | Soluble MHC artificial antigen presenting cells |
US6800748B2 (en) * | 2001-01-25 | 2004-10-05 | Large Scale Biology Corporation | Cytoplasmic inhibition of gene expression and expression of a foreign protein in a monocot plant by a plant viral vector |
EP2336167B1 (en) | 2001-03-14 | 2019-05-29 | Dako Denmark A/S | MHC molecule constructs and their uses for diagnosis and therapy |
WO2002093129A2 (en) * | 2001-05-15 | 2002-11-21 | University Of Medicine & Dentistry Of New Jersey | Methods for analyzing interactions between proteins in live and intact cells |
AU2002310321A1 (en) | 2001-06-04 | 2002-12-16 | Corixa Corporation | Compositions and methods for high-level, large-scale production of recombinant proteins |
US20030017134A1 (en) | 2001-06-19 | 2003-01-23 | Technion Research And Development Foundation Ltd. | Methods and pharmaceutical compositions for immune deception, particularly useful in the treatment of cancer |
AU2002368044A1 (en) | 2001-06-22 | 2004-04-19 | Maxygen, Inc. | Co-stimulatory molecules |
AU2002322211A1 (en) | 2001-07-12 | 2003-01-29 | Canvac | Methods and compisitions for activation human t cells in vitro |
US20040038349A1 (en) | 2001-07-27 | 2004-02-26 | Hilbert David M. | Heteromultimeric TNF ligand family members |
MXPA04005266A (en) | 2001-12-04 | 2004-10-11 | Merck Patent Gmbh | Immunocytokines with modulated selectivity. |
US8895020B2 (en) | 2002-04-19 | 2014-11-25 | Washington University | Single chain trimers and uses therefor |
US7432351B1 (en) | 2002-10-04 | 2008-10-07 | Mayo Foundation For Medical Education And Research | B7-H1 variants |
WO2004076488A1 (en) | 2003-02-27 | 2004-09-10 | Theravision Gmbh | A molecule which binds cd80 and cd86 |
AU2003901876A0 (en) | 2003-04-17 | 2003-05-08 | The Macfarlane Burnet Institute For Medical Research And Public Health | Viral vector |
US20050042641A1 (en) | 2003-05-27 | 2005-02-24 | Cold Spring Harbor Laboratory | In vivo high throughput selection of RNAi probes |
US7470513B2 (en) | 2003-11-10 | 2008-12-30 | Academia Sinica | Risk assessment for adverse drug reactions |
US20060234205A1 (en) | 2004-03-05 | 2006-10-19 | Chiron Corporation | In vitro test system for predicting patient tolerability of therapeutic agents |
DE102004014983A1 (en) | 2004-03-26 | 2005-10-20 | Univ Stuttgart | Recombinant polypeptides of the members of the TNF ligand family and their use |
US20060034850A1 (en) | 2004-05-27 | 2006-02-16 | Weidanz Jon A | Antibodies as T cell receptor mimics, methods of production and uses thereof |
US7670595B2 (en) | 2004-06-28 | 2010-03-02 | Merck Patent Gmbh | Fc-interferon-beta fusion proteins |
KR20080082628A (en) * | 2005-11-10 | 2008-09-11 | 리셉터 바이오로직스 인크 | Methods for production of receptor and ligand isoforms |
US8518697B2 (en) | 2006-04-04 | 2013-08-27 | Washington University | Single chain trimers and uses therefor |
WO2007136778A2 (en) | 2006-05-19 | 2007-11-29 | Teva Pharmaceutical Industries, Ltd. | Fusion proteins, uses thereof and processes for producing same |
EP1889851A1 (en) | 2006-08-18 | 2008-02-20 | Charite Universitätsmedizin-Berlin | PAX2 and PAX8 as targets for immunologic and molecular tumour treatment strategies |
US8992937B2 (en) | 2006-08-28 | 2015-03-31 | Washington University | Disulfide trap MHC class I molecules and uses therefor |
DK2479275T3 (en) | 2006-12-28 | 2015-12-14 | Int Inst Cancer Immunology Inc | HLA-A * 1101-restricted WT1 peptide or pharmaceutical composition comprising this |
ES2527412T3 (en) | 2007-02-15 | 2015-01-23 | Mannkind Corporation | Method to increase the response of T lymphocytes |
WO2008116468A2 (en) | 2007-03-26 | 2008-10-02 | Dako Denmark A/S | Mhc peptide complexes and uses thereof in infectious diseases |
WO2008134461A2 (en) | 2007-04-27 | 2008-11-06 | Dow Global Technologies, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
US8926961B2 (en) | 2007-10-03 | 2015-01-06 | Board Of Trustees Of The University Of Arkansas | HPV E6 protein T cell epitopes and uses thereof |
CN101418309B (en) | 2007-10-23 | 2011-05-04 | 中国农业科学院上海兽医研究所 | Cloning, expression and application of eimeria tenella protein disulfide isomerase gene |
DE102008023820A1 (en) | 2008-05-08 | 2009-11-12 | Aicuris Gmbh & Co. Kg | An agent for the treatment and / or prophylaxis of an autoimmune disease and for the production of regulatory T cells |
TW201008574A (en) | 2008-08-19 | 2010-03-01 | Oncotherapy Science Inc | INHBB epitope peptides and vaccines containing the same |
WO2010037395A2 (en) | 2008-10-01 | 2010-04-08 | Dako Denmark A/S | Mhc multimers in cancer vaccines and immune monitoring |
EP2184070A1 (en) | 2008-11-07 | 2010-05-12 | Hla-G Technologies | HLA-G proteins and pharmaceutical uses thereof |
MX362028B (en) | 2009-02-03 | 2019-01-04 | Amunix Pharmaceuticals Inc | Extended recombinant polypeptides and compositions comprising same. |
US20120178703A1 (en) | 2009-06-25 | 2012-07-12 | Commisariat A L'energie Atomique Et Aux Energies Alternatives | Multimeric polypeptides of hla-g including at least two alpha3 domains and pharmaceutical uses thereof |
MX343747B (en) * | 2009-11-24 | 2016-11-22 | Medimmune Ltd | Targeted binding agents against b7-h1. |
WO2011066342A2 (en) * | 2009-11-24 | 2011-06-03 | Amplimmune, Inc. | Simultaneous inhibition of pd-l1/pd-l2 |
JP6251570B2 (en) | 2010-09-21 | 2017-12-20 | アルター・バイオサイエンス・コーポレーション | Multimeric IL-15 soluble fusion molecule and methods for its production and use |
WO2012088446A1 (en) | 2010-12-22 | 2012-06-28 | Board Of Trustees Of The Leland Stanford Junior University | Superagonists and antagonists of interleukin-2 |
WO2012127464A2 (en) | 2011-03-23 | 2012-09-27 | Gavish-Galilee Bio Applications Ltd | Constitutively activated t cells for use in adoptive cell therapy |
AR086982A1 (en) | 2011-06-22 | 2014-02-05 | Hoffmann La Roche | ELIMINATION OF DIANA CELLS BY SPECIFIC CYTOTOXIC T-CELLS OF VIRUSES USING COMPLEXES THAT INCLUDE MHC CLASS I |
EP3357511B1 (en) | 2011-06-30 | 2020-05-13 | Genzyme Corporation | Inhibitors of t-cell activation |
DE112011100879A5 (en) | 2011-08-30 | 2013-11-14 | Jacobs University Bremen Ggmbh | Gene codes for an MHC class I molecule, plasmid, expression system, protein, multimer, reagent and kit for analyzing a T-cell frequency |
US8956619B2 (en) | 2011-10-25 | 2015-02-17 | University Of Maryland, Baltimore County | Soluble CD80 as a therapeutic to reverse immune supression in cancer patients |
RS61033B1 (en) * | 2011-11-28 | 2020-12-31 | Merck Patent Gmbh | Anti-pd-l1 antibodies and uses thereof |
US20150104413A1 (en) | 2012-01-13 | 2015-04-16 | Memorial Sloan Kettering Cancer Center | Immunogenic wt-1 peptides and methods of use thereof |
CA2863658C (en) | 2012-02-03 | 2023-03-14 | Emory University | Immunostimulatory compositions, particles, and uses related thereto |
US20140044675A1 (en) | 2012-08-10 | 2014-02-13 | Roche Glycart Ag | Interleukin-2 fusion proteins and uses thereof |
CN104781279A (en) | 2012-11-30 | 2015-07-15 | 罗切格利卡特公司 | Removal of cancer cells by circulating virus-specific cytotoxic t-cells using cancer cell targeted MHC class I comprising multi-function proteins |
CA2894511C (en) | 2012-12-11 | 2021-12-07 | Albert Einstein College Of Medicine Of Yeshiva University | Methods for high throughput receptor:ligand identification |
US10815273B2 (en) | 2013-01-15 | 2020-10-27 | Memorial Sloan Kettering Cancer Center | Immunogenic WT-1 peptides and methods of use thereof |
US20140242077A1 (en) | 2013-01-23 | 2014-08-28 | Abbvie, Inc. | Methods and compositions for modulating an immune response |
ES2691091T3 (en) | 2013-03-29 | 2018-11-23 | Sumitomo Dainippon Pharma Co., Ltd. | WT1 antigenic peptide conjugate vaccine |
GB201311475D0 (en) | 2013-06-27 | 2013-08-14 | Alligator Bioscience Ab | Polypeptides |
JP6875126B2 (en) | 2014-01-21 | 2021-05-19 | アルバート アインシュタイン カレッジ オブ メディシン | Cell platform for rapid and comprehensive T cell immune monitoring |
WO2015130766A1 (en) | 2014-02-25 | 2015-09-03 | Memorial Sloan-Kettering Cancer Center | Antigen-binding proteins specific for hla-a2-restricted wilms tumor 1 peptide |
US10253075B2 (en) | 2014-02-26 | 2019-04-09 | tella, Inc. | WT1 antigenic polypeptide, and anti-tumor agent containing said polypeptide |
WO2015164815A1 (en) | 2014-04-24 | 2015-10-29 | The Board Of Trustees Of The Leland Stanford Junior University | Superagonists, partial agonists and antagonists of interleukin-2 |
BR112016027897A2 (en) | 2014-06-18 | 2017-10-24 | Albert Einstein College Medicine Inc | multimeric polypeptide, nucleic acid, recombinant expression vector, genetically modified host cell, composition, method, and method of treating an infection in an individual |
CN106604742B (en) | 2014-07-03 | 2019-01-11 | 百济神州有限公司 | Anti- PD-L1 antibody and its purposes as therapeutic agent and diagnosticum |
RS59789B1 (en) | 2014-07-21 | 2020-02-28 | Delinia Inc | Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases |
JP6800141B2 (en) | 2014-08-12 | 2020-12-16 | マサチューセッツ インスティテュート オブ テクノロジー | Synergistic tumor treatment with IL-2 and integrin-binding FC fusion protein |
EP3191131A4 (en) | 2014-08-21 | 2018-09-05 | The General Hospital Corporation | Tumor necrosis factor superfamily and tnf-like ligand muteins and methods of preparing and using the same |
DK3186283T3 (en) | 2014-08-29 | 2020-03-02 | Hoffmann La Roche | Combination therapy with tumor-targeted IL-2 immunocytokine variants and antibodies against human PD-L1 |
JP2018512856A (en) | 2015-04-17 | 2018-05-24 | アルパイン イミューン サイエンシズ インコーポレイテッド | Immunomodulating proteins with tunable affinity |
CA2993429A1 (en) | 2015-07-31 | 2017-02-09 | Tarveda Therapeutics, Inc. | Compositions and methods for immuno-oncology therapies |
CN106565836B (en) | 2015-10-10 | 2020-08-18 | 中国科学院广州生物医药与健康研究院 | High affinity soluble PDL-1 molecules |
JP2019516665A (en) | 2016-03-02 | 2019-06-20 | キュー バイオファーマ, インコーポレイテッド | T cell regulatory multimeric polypeptides and methods of use thereof |
WO2017151940A2 (en) | 2016-03-03 | 2017-09-08 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
CN109071623B (en) | 2016-05-04 | 2022-05-27 | 美国安进公司 | Interleukin-2 muteins for expansion of T regulatory cells |
EP3458095A4 (en) | 2016-05-18 | 2019-11-27 | Albert Einstein College of Medicine | Variant pd-l1 polypeptides, t-cell modulatory multimeric polypeptides, and methods of use thereof |
WO2019051126A1 (en) | 2017-09-07 | 2019-03-14 | Cue Biopharma, Inc. | Antigen-presenting polypeptides with chemical conjugation sites and methods of use thereof |
-
2013
- 2013-12-05 CA CA2894511A patent/CA2894511C/en active Active
- 2013-12-05 CN CN201811139644.3A patent/CN109324190A/en active Pending
- 2013-12-05 JP JP2015545835A patent/JP2016500255A/en not_active Ceased
- 2013-12-05 AU AU2013359907A patent/AU2013359907B2/en not_active Ceased
- 2013-12-05 BR BR112015013557-9A patent/BR112015013557B1/en active IP Right Grant
- 2013-12-05 WO PCT/US2013/073275 patent/WO2014093118A1/en active Application Filing
- 2013-12-05 US US14/649,176 patent/US10048271B2/en active Active
- 2013-12-05 SG SG11201504558TA patent/SG11201504558TA/en unknown
- 2013-12-05 EP EP19197120.9A patent/EP3640375A3/en not_active Withdrawn
- 2013-12-05 SG SG10201808463RA patent/SG10201808463RA/en unknown
- 2013-12-05 EP EP13862361.6A patent/EP2931949B1/en active Active
- 2013-12-05 KR KR1020157017981A patent/KR102208505B1/en active IP Right Grant
- 2013-12-05 CN CN201380071758.8A patent/CN105121715B/en active Active
-
2015
- 2015-05-31 IL IL239096A patent/IL239096B/en active IP Right Grant
-
2016
- 2016-05-30 HK HK16106096.2A patent/HK1218144A1/en not_active IP Right Cessation
-
2018
- 2018-03-14 AU AU2018201812A patent/AU2018201812B2/en not_active Ceased
- 2018-07-25 US US16/044,608 patent/US11226339B2/en active Active
- 2018-11-05 IL IL262785A patent/IL262785B/en active IP Right Grant
-
2019
- 2019-11-05 JP JP2019200491A patent/JP7128792B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
BR112015013557B1 (en) | 2021-12-14 |
CN105121715B (en) | 2018-10-26 |
WO2014093118A1 (en) | 2014-06-19 |
US10048271B2 (en) | 2018-08-14 |
AU2013359907A1 (en) | 2015-06-18 |
EP2931949A1 (en) | 2015-10-21 |
CN109324190A (en) | 2019-02-12 |
EP2931949B1 (en) | 2019-09-18 |
IL239096B (en) | 2019-03-31 |
EP3640375A3 (en) | 2020-07-29 |
IL262785A (en) | 2018-12-31 |
CN105121715A (en) | 2015-12-02 |
AU2013359907B2 (en) | 2018-01-18 |
KR102208505B1 (en) | 2021-01-27 |
JP2016500255A (en) | 2016-01-12 |
IL262785B (en) | 2020-04-30 |
US20200011875A1 (en) | 2020-01-09 |
CA2894511C (en) | 2021-12-07 |
HK1218144A1 (en) | 2017-02-03 |
JP2020043860A (en) | 2020-03-26 |
EP3640375A2 (en) | 2020-04-22 |
BR112015013557A2 (en) | 2020-01-14 |
IL239096A0 (en) | 2015-07-30 |
CA2894511A1 (en) | 2014-06-19 |
EP2931949A4 (en) | 2016-07-27 |
AU2018201812B2 (en) | 2020-09-10 |
AU2018201812A1 (en) | 2018-04-05 |
KR20150094674A (en) | 2015-08-19 |
US11226339B2 (en) | 2022-01-18 |
US20160011204A1 (en) | 2016-01-14 |
JP7128792B2 (en) | 2022-08-31 |
SG10201808463RA (en) | 2018-11-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL262785B (en) | Methods for high throughput receptor:ligand identification | |
IL239262A0 (en) | Methods for screening | |
HK1214504A1 (en) | Methods for treating anemia | |
ZA201501833B (en) | Method for obtaining 1-kestone | |
EP2939260A4 (en) | Method for preparing samples for imaging | |
ZA201409403B (en) | Process for reforming hydrocarbons | |
PL2914386T3 (en) | Device for sorting | |
GB201212902D0 (en) | Combinatoric encoding methods for microarrays | |
IL237436A0 (en) | Method for screening cancer | |
EP2908119A4 (en) | Method for detecting nano-particles | |
EP2828639A4 (en) | Improved apparatus for detecting particles | |
PT3165483T (en) | Apparatus for sorting objects | |
EP2892042A4 (en) | Intellectual productivity analysis device, program | |
PL2876447T3 (en) | Method for detecting cancer | |
EP2837628A4 (en) | Method for preparing rivaroxaban intermediate | |
PL2876446T3 (en) | Method for detecting cancer | |
HK1201800A1 (en) | Method for forming packages | |
SG11201503816PA (en) | Alkylating process | |
EP2855433A4 (en) | Process for preparing dihalopyridines | |
EP2819995A4 (en) | Process for preparing 3-methylsulfonylpropionitrile | |
EP2849689A4 (en) | Modified pusher apparatus | |
EP2818476A4 (en) | Method for preparing 3-o-benzyl-1,2-o-isopropylidene- -l-furan idose | |
EP2835001A4 (en) | Identification for apparatuses | |
EP2888591A4 (en) | Method for improved cell identification | |
EP2840305A4 (en) | Method for preparing reflector |