SG11202108089SA - Administration of pd-1 inhibitors for treating skin cancer - Google Patents

Administration of pd-1 inhibitors for treating skin cancer

Info

Publication number
SG11202108089SA
SG11202108089SA SG11202108089SA SG11202108089SA SG11202108089SA SG 11202108089S A SG11202108089S A SG 11202108089SA SG 11202108089S A SG11202108089S A SG 11202108089SA SG 11202108089S A SG11202108089S A SG 11202108089SA SG 11202108089S A SG11202108089S A SG 11202108089SA
Authority
SG
Singapore
Prior art keywords
inhibitors
administration
skin cancer
treating skin
treating
Prior art date
Application number
SG11202108089SA
Inventor
Matthew G Fury
Israel Lowy
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of SG11202108089SA publication Critical patent/SG11202108089SA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
SG11202108089SA 2019-02-28 2020-02-27 Administration of pd-1 inhibitors for treating skin cancer SG11202108089SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962811827P 2019-02-28 2019-02-28
PCT/US2020/020018 WO2020176699A1 (en) 2019-02-28 2020-02-27 Administration of pd-1 inhibitors for treating skin cancer

Publications (1)

Publication Number Publication Date
SG11202108089SA true SG11202108089SA (en) 2021-08-30

Family

ID=70057261

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202108089SA SG11202108089SA (en) 2019-02-28 2020-02-27 Administration of pd-1 inhibitors for treating skin cancer

Country Status (12)

Country Link
US (1) US20220259313A1 (en)
EP (1) EP3930848A1 (en)
JP (1) JP2022521800A (en)
KR (1) KR20210134690A (en)
CN (1) CN113490529A (en)
AU (1) AU2020228296A1 (en)
CA (1) CA3137361A1 (en)
IL (1) IL285050A (en)
MA (1) MA55084A (en)
MX (1) MX2021010228A (en)
SG (1) SG11202108089SA (en)
WO (1) WO2020176699A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI680138B (en) * 2014-01-23 2019-12-21 美商再生元醫藥公司 Human antibodies to pd-l1
JP2024507144A (en) * 2021-02-11 2024-02-16 リジェネロン・ファーマシューティカルズ・インコーポレイテッド Method of treating cancer by administering a neoadjuvant PD-1 inhibitor

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1210428T3 (en) 1999-08-23 2015-06-15 Dana Farber Cancer Inst Inc PD-1, a receptor for B7-4 AND USE THEREOF
HUE10161767T1 (en) 2002-07-03 2019-03-28 Ono Pharmaceutical Co Immunopotentiating compositions comprising anti-pd-l1 antibodies
US7488802B2 (en) 2002-12-23 2009-02-10 Wyeth Antibodies against PD-1
CA3151350A1 (en) 2005-05-09 2006-11-16 E. R. Squibb & Sons, L.L.C. Human monoclonal antibodies to programmed death 1 (pd-1) and methods for treating cancer using anti-pd-1 antibodies alone or in combination with other immunotherapeutics
EA019344B1 (en) 2005-07-01 2014-03-31 МЕДАРЕКС, Эл.Эл.Си. Human monoclonal antibodies to programmed death ligand 1 (pd-l1) and uses thereof
PT2170959E (en) 2007-06-18 2014-01-07 Merck Sharp & Dohme Antibodies to human programmed death receptor pd-1
EP2262837A4 (en) 2008-03-12 2011-04-06 Merck Sharp & Dohme Pd-1 binding proteins
CN102203132A (en) 2008-08-25 2011-09-28 安普利穆尼股份有限公司 Compositions of PD-1 antagonists and methods of use
WO2010036959A2 (en) 2008-09-26 2010-04-01 Dana-Farber Cancer Institute Human anti-pd-1, pd-l1, and pd-l2 antibodies and uses therefor
MX356367B (en) 2008-12-09 2018-05-25 Genentech Inc Anti-pd-l1 antibodies and their use to enhance t-cell function.
EP2734551B1 (en) 2011-07-24 2018-01-10 Cure Tech Ltd. Variants of humanized immunomodulatory monoclonal antibodies
WO2013079174A1 (en) 2011-11-28 2013-06-06 Merck Patent Gmbh Anti-pd-l1 antibodies and uses thereof
AU2013267161A1 (en) 2012-05-31 2014-11-20 Sorrento Therapeutics, Inc. Antigen binding proteins that bind PD-L1
MY186099A (en) 2012-05-31 2021-06-22 Genentech Inc Methods of treating cancer using pd-l1 axis binding antagonists and vegf antagonists
US9308236B2 (en) 2013-03-15 2016-04-12 Bristol-Myers Squibb Company Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions
TWI681969B (en) * 2014-01-23 2020-01-11 美商再生元醫藥公司 Human antibodies to pd-1
TWI680138B (en) 2014-01-23 2019-12-21 美商再生元醫藥公司 Human antibodies to pd-l1
WO2016022630A1 (en) 2014-08-05 2016-02-11 Jiping Zha Anti-pd-l1 antibodies
IL292449B2 (en) 2015-03-13 2024-02-01 Cytomx Therapeutics Inc Nucleic acids encoding anti-pdl1 antibodie and methods of producing same
AR105654A1 (en) 2015-08-24 2017-10-25 Lilly Co Eli ANTIBODIES PD-L1 (LINKING 1 OF PROGRAMMED CELL DEATH)
CA3007671A1 (en) * 2015-12-17 2017-06-22 Novartis Ag Antibody molecules to pd-1 and uses thereof
BR112018012801B1 (en) 2015-12-22 2024-03-12 Regeneron Pharmaceuticals, Inc USES OF A COMBINATION OF ANTI-PD-1 ANTIBODIES AND ANTI-CD20/ANTI-CD3 BIESPECIFIC ANTIBODIES AND OF A PHARMACEUTICAL COMPOSITION
RU2745195C2 (en) 2016-04-07 2021-03-22 Кемосентрикс, Инк. Reduction of tumor mass by injecting ccr1 antagonists in combination with pd-1 inhibitors or pd-l1 inhibitors
TWI755395B (en) * 2016-05-13 2022-02-21 美商再生元醫藥公司 Combination of anti-pd-1 antibodies and radiation to treat cancer
MA47604A (en) * 2017-02-21 2020-01-01 Regeneron Pharma ANTI-PD-1 ANTIBODIES FOR THE TREATMENT OF LUNG CANCER
US11603407B2 (en) 2017-04-06 2023-03-14 Regeneron Pharmaceuticals, Inc. Stable antibody formulation
CA3067909A1 (en) * 2017-06-19 2018-12-27 Medicenna Therapeutics Inc. Uses and methods for il-2 superagonists, agonists, and fusions thereof

Also Published As

Publication number Publication date
WO2020176699A1 (en) 2020-09-03
MA55084A (en) 2022-01-05
JP2022521800A (en) 2022-04-12
EP3930848A1 (en) 2022-01-05
KR20210134690A (en) 2021-11-10
AU2020228296A1 (en) 2021-10-14
US20220259313A1 (en) 2022-08-18
CN113490529A (en) 2021-10-08
IL285050A (en) 2021-09-30
CA3137361A1 (en) 2020-09-03
MX2021010228A (en) 2021-10-26

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