JP2006524039A - 変異型Ｆｃ領域を含む抗体の同定および作製ならびにその利用法 - Google Patents

変異型Ｆｃ領域を含む抗体の同定および作製ならびにその利用法 Download PDF

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JP2006524039A
JP2006524039A JP2006500901A JP2006500901A JP2006524039A JP 2006524039 A JP2006524039 A JP 2006524039A JP 2006500901 A JP2006500901 A JP 2006500901A JP 2006500901 A JP2006500901 A JP 2006500901A JP 2006524039 A JP2006524039 A JP 2006524039A
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ステイブンヘイゲン，ジェフリー
ヴィー，スジャータ
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マクロジェニクス，インコーポレーテッド
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JP2006500901A 2003-01-09 2004-01-09 変異型Ｆｃ領域を含む抗体の同定および作製ならびにその利用法 Pending JP2006524039A (ja)

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US43949803P 2003-01-09 2003-01-09
US45604103P 2003-03-19 2003-03-19
US51454903P 2003-10-23 2003-10-23
PCT/US2004/000643 WO2004063351A2 (en) 2003-01-09 2004-01-09 IDENTIFICATION AND ENGINEERING OF ANTIBODIES WITH VARIANT Fc REGIONS AND METHODS OF USING SAME

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JP2006524039A5 JP2006524039A5 (https=) 2007-03-29

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JP2010292632A Pending JP2011121954A (ja) 2003-01-09 2010-12-28 変異型Ｆｃ領域を含む抗体の同定および作製ならびにその利用法
JP2014203774A Expired - Fee Related JP6389093B2 (ja) 2003-01-09 2014-10-02 変異型Ｆｃ領域を含む抗体の同定および作製ならびにその利用法

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JP2014203774A Expired - Fee Related JP6389093B2 (ja) 2003-01-09 2014-10-02 変異型Ｆｃ領域を含む抗体の同定および作製ならびにその利用法

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US (5) US7355008B2 (https=)
EP (2) EP2368578A1 (https=)
JP (3) JP2006524039A (https=)
AU (1) AU2004204494B2 (https=)
CA (1) CA2512729C (https=)
ES (1) ES2897506T3 (https=)
IL (1) IL169603A (https=)
WO (1) WO2004063351A2 (https=)

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007525443A (ja) * 2003-05-02 2007-09-06 ゼンコー・インコーポレイテッド 最適化Ｆｃ変異体およびそれらの生成方法
JP2011121954A (ja) * 2003-01-09 2011-06-23 Macrogenics Inc 変異型Ｆｃ領域を含む抗体の同定および作製ならびにその利用法
WO2013002362A1 (ja) * 2011-06-30 2013-01-03 中外製薬株式会社 ヘテロ二量化ポリペプチド
JP2013528357A (ja) * 2010-03-29 2013-07-11 ザイムワークス，インコーポレイテッド 強化又は抑制されたエフェクター機能を有する抗体
JP2014509857A (ja) * 2011-03-16 2014-04-24 アムジエン・インコーポレーテツド Ｆｃ変異体
JP2016512216A (ja) * 2013-03-15 2016-04-25 ラボラトワール・フランセ・デュ・フラクシオンマン・エ・デ・ビョテクノロジーＬａｂｏｒａｔｏｉｒｅ Ｆｒａｎｃａｉｓ Ｄｕ Ｆｒａｃｔｉｏｎｎｅｍｅｎｔ Ｅｔ Ｄｅｓ Ｂｉｏｔｅｃｈｎｏｌｏｇｉｅｓ 主要電荷アイソフォームに富んだ抗体組成物を含む新規な薬剤
JP2016523930A (ja) * 2013-07-05 2016-08-12 エイチ リー モフィット キャンサー センター アンド リサーチ インスティテュート インコーポレイテッド 骨髄異形成症候群（ｍｄｓ）を治療するための可溶性ｃｄ３３
US10766960B2 (en) 2012-12-27 2020-09-08 Chugai Seiyaku Kabushiki Kaisha Heterodimerized polypeptide
US10919953B2 (en) 2012-08-24 2021-02-16 Chugai Seiyaku Kabushiki Kaisha FcgammaRIIB-specific Fc region variant
JP2021019632A (ja) * 2011-12-23 2021-02-18 ファイザー・インク 部位特異的コンジュゲーションのための操作された抗体定常領域、ならびにそのための方法および使用
JP2021050235A (ja) * 2015-07-06 2021-04-01 ラボラトワール・フランセ・デュ・フラクシオンマン・エ・デ・ビョテクノロジーＬａｂｏｒａｔｏｉｒｅ Ｆｒａｎｃａｉｓ Ｄｕ Ｆｒａｃｔｉｏｎｎｅｍｅｎｔ Ｅｔ Ｄｅｓ Ｂｉｏｔｅｃｈｎｏｌｏｇｉｅｓ 免疫療法における改変Ｆｃ断片の使用
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CA2512729C (en) 2014-09-16
EP1587540B1 (en) 2021-09-15
EP2368578A1 (en) 2011-09-28
US7355008B2 (en) 2008-04-08
IL169603A0 (en) 2007-07-04
US8003774B2 (en) 2011-08-23
US8192737B2 (en) 2012-06-05
IL169603A (en) 2016-08-31
ES2897506T3 (es) 2022-03-01
US20080138344A1 (en) 2008-06-12
US20110305714A1 (en) 2011-12-15
AU2004204494A1 (en) 2004-07-29
EP1587540A2 (en) 2005-10-26
US20080131435A1 (en) 2008-06-05
US9028815B2 (en) 2015-05-12
AU2004204494B2 (en) 2011-09-29
JP2011121954A (ja) 2011-06-23
WO2004063351A3 (en) 2005-03-31
EP1587540A4 (en) 2008-09-10
JP6389093B2 (ja) 2018-09-12
WO2004063351A2 (en) 2004-07-29
US20050037000A1 (en) 2005-02-17

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