ES2669310T3 - Anticuerpos y otras moléculas que se unen con B7-H1 y PD-1 - Google Patents
Anticuerpos y otras moléculas que se unen con B7-H1 y PD-1 Download PDFInfo
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- ES2669310T3 ES2669310T3 ES12774724.4T ES12774724T ES2669310T3 ES 2669310 T3 ES2669310 T3 ES 2669310T3 ES 12774724 T ES12774724 T ES 12774724T ES 2669310 T3 ES2669310 T3 ES 2669310T3
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Landscapes
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| US20100303828A1 (en) | 2008-01-31 | 2010-12-02 | INSERM Institut National de la Sante et de la Recherche Medicale) | Antibodies Against Human CD39 and Use Thereof for Inhibiting T Regulatory Cells Activity |
| PT2376535T (pt) | 2008-12-09 | 2017-06-23 | Hoffmann La Roche | Anticorpos anti-pd-l1 e a sua utilização para a melhoria do funcionamento das células t |
| US9163087B2 (en) | 2010-06-18 | 2015-10-20 | The Brigham And Women's Hospital, Inc. | Bi-specific antibodies against TIM-3 and PD-1 for immunotherapy in chronic immune conditions |
| ES2671748T3 (es) | 2011-07-21 | 2018-06-08 | Tolero Pharmaceuticals, Inc. | Inhibidores heterocíclicos de proteína quinasas |
| CA3213528A1 (en) | 2012-05-15 | 2013-11-21 | Bristol-Myers Squibb Company | Cancer immunotherapy by disrupting pd-1/pd-l1 signaling |
| CN112587671A (zh) | 2012-07-18 | 2021-04-02 | 博笛生物科技有限公司 | 癌症的靶向免疫治疗 |
| HUE035503T2 (en) | 2012-10-02 | 2018-05-02 | Bristol Myers Squibb Co | Combination of anti-kir antibodies and anti-pd-1 antibodies to treat cancer |
| WO2014100439A2 (en) * | 2012-12-19 | 2014-06-26 | Amplimmune, Inc. | B7-h4 specific antibodies, and compositions and methods of use thereof |
| SG11201504765VA (en) * | 2012-12-21 | 2015-07-30 | Amplimmune Inc | Anti-h7cr antibodies |
| WO2014121085A1 (en) | 2013-01-31 | 2014-08-07 | Thomas Jefferson University | Pd-l1 and pd-l2-based fusion proteins and uses thereof |
| ES2642201T3 (es) | 2013-03-06 | 2017-11-15 | Astrazeneca Ab | Inhibidores de quinazolina de formas mutantes de activación del receptor del factor de crecimiento epidérmico |
| KR20230070054A (ko) * | 2013-03-15 | 2023-05-19 | 제넨테크, 인크. | Pd-1 및 pd-l1 관련 상태를 치료하기 위한 바이오마커 및 방법 |
| WO2014194293A1 (en) * | 2013-05-30 | 2014-12-04 | Amplimmune, Inc. | Improved methods for the selection of patients for pd-1 or b7-h4 targeted therapies, and combination therapies thereof |
| US20160145355A1 (en) * | 2013-06-24 | 2016-05-26 | Biomed Valley Discoveries, Inc. | Bispecific antibodies |
| KR102861895B1 (ko) | 2013-08-08 | 2025-09-22 | 싸이튠 파마 | 병용 약학 조성물 |
| DK3444271T3 (da) | 2013-08-08 | 2022-01-10 | Cytune Pharma | Il-15- og il-15r-alfa-sushi-domænebaserede modulokiner |
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| KR102260855B1 (ko) * | 2013-09-13 | 2021-06-04 | 제넨테크, 인크. | 세포주에서 숙주 세포 단백질 및 재조합 폴리펩티드 생성물을 검출 및 정량화하기 위한 조성물 및 방법 |
| CA3078121A1 (en) * | 2013-09-13 | 2015-03-19 | Beigene Switzerland Gmbh | Anti-pd1 antibodies and their use as therapeutics and diagnostics |
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| EP3508502B1 (en) | 2013-09-20 | 2023-04-26 | Bristol-Myers Squibb Company | Combination of anti-lag-3 antibodies and anti-pd-1 antibodies to treat tumors |
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| AU2014361473B2 (en) | 2013-12-12 | 2019-09-26 | Jiangsu Hengrui Medicine Co., Ltd. | PD-1 antibody, antigen-binding fragment thereof, and medical application thereof |
| PL3466949T3 (pl) | 2013-12-24 | 2021-05-31 | Bristol-Myers Squibb Company | Związek tricykliczny jako środki przeciwrakowe |
| CA2936375A1 (en) | 2014-01-10 | 2015-07-16 | Shanghai Birdie Biotech, Inc. | Compounds and compositions for treating her2 positive tumors |
| TWI681969B (zh) | 2014-01-23 | 2020-01-11 | 美商再生元醫藥公司 | 針對ｐｄ-１的人類抗體 |
| TWI680138B (zh) | 2014-01-23 | 2019-12-21 | 美商再生元醫藥公司 | 抗ｐｄ-ｌ１之人類抗體 |
| JOP20200094A1 (ar) | 2014-01-24 | 2017-06-16 | Dana Farber Cancer Inst Inc | جزيئات جسم مضاد لـ pd-1 واستخداماتها |
| JOP20200096A1 (ar) | 2014-01-31 | 2017-06-16 | Children’S Medical Center Corp | جزيئات جسم مضاد لـ tim-3 واستخداماتها |
| GB201403775D0 (en) | 2014-03-04 | 2014-04-16 | Kymab Ltd | Antibodies, uses & methods |
| KR20220127940A (ko) | 2014-03-05 | 2022-09-20 | 브리스톨-마이어스 스큅 컴퍼니 | 항-pd-1 항체 및 또 다른 항암제의 조합물을 이용한 신장암의 치료 |
| US10618963B2 (en) | 2014-03-12 | 2020-04-14 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| US10519237B2 (en) | 2014-03-12 | 2019-12-31 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| KR20230097209A (ko) | 2014-03-12 | 2023-06-30 | 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 | Cns의 질환 및 손상을 치료하기 위한 전신적 조절 t 세포 수준 또는 활성의 감소 |
| US9394365B1 (en) | 2014-03-12 | 2016-07-19 | Yeda Research And Development Co., Ltd | Reducing systemic regulatory T cell levels or activity for treatment of alzheimer's disease |
| US20150259420A1 (en) | 2014-03-14 | 2015-09-17 | Novartis Ag | Antibody molecules to lag-3 and uses thereof |
| BR112016026559A8 (pt) | 2014-05-15 | 2021-07-13 | Bristol Myers Squibb Co | uso de um anticorpo anti-pd-1 e outro agente anticâncer em combinação com quimioterapia dupla com base em platina (pt-dc) e kit |
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| SMT201900668T1 (it) | 2014-06-06 | 2020-01-14 | Bristol Myers Squibb Co | Anticorpi contro il recettore per il fattore di necrosi tumorale indotto da glucocorticoidi(gitr)e loro usi |
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| FI4001311T3 (fi) | 2014-07-09 | 2026-01-27 | Birdie Biopharmaceuticals Inc | Pd-l1/pd-1-vasta-aineiden yhdistelmiä kasvaimien hoitoon |
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| BR112017000497B1 (pt) | 2014-07-11 | 2023-12-26 | Ventana Medical Systems, Inc | Anticorpo isolado, célula hospedeira procariótica, imunoconjugado e método de detecção da presença ou do nível de expressão de pd-l1 |
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| WO2016022994A2 (en) * | 2014-08-08 | 2016-02-11 | The Board Of Trustees Of The Leland Stanford Junior University | High affinity pd-1 agents and methods of use |
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-
2012
- 2012-04-19 RS RS20180683A patent/RS57324B1/sr unknown
- 2012-04-19 LT LTEP12774724.4T patent/LT2699264T/lt unknown
- 2012-04-19 RU RU2013151455A patent/RU2625034C2/ru not_active IP Right Cessation
- 2012-04-19 EP EP18161596.4A patent/EP3403672A1/en not_active Withdrawn
- 2012-04-19 SM SM20180294T patent/SMT201800294T1/it unknown
- 2012-04-19 CA CA2833636A patent/CA2833636A1/en not_active Abandoned
- 2012-04-19 SI SI201231320T patent/SI2699264T1/en unknown
- 2012-04-19 ES ES12774724.4T patent/ES2669310T3/es active Active
- 2012-04-19 PT PT127747244T patent/PT2699264T/pt unknown
- 2012-04-19 HR HRP20180893TT patent/HRP20180893T1/hr unknown
- 2012-04-19 DK DK12774724.4T patent/DK2699264T3/en active
- 2012-04-19 PL PL12774724T patent/PL2699264T3/pl unknown
- 2012-04-19 MX MX2013012088A patent/MX338353B/es active IP Right Grant
- 2012-04-19 JP JP2014506544A patent/JP6072771B2/ja not_active Expired - Fee Related
- 2012-04-19 EP EP12774724.4A patent/EP2699264B1/en active Active
- 2012-04-19 AU AU2012245477A patent/AU2012245477C1/en not_active Ceased
- 2012-04-19 HU HUE12774724A patent/HUE037651T2/hu unknown
- 2012-04-19 US US14/111,402 patent/US9205148B2/en not_active Expired - Fee Related
- 2012-04-19 WO PCT/US2012/034223 patent/WO2012145493A1/en not_active Ceased
- 2012-04-19 KR KR1020137030691A patent/KR101970025B1/ko not_active Expired - Fee Related
- 2012-04-19 CN CN201280030691.9A patent/CN103608040B/zh not_active Expired - Fee Related
-
2015
- 2015-10-29 US US14/926,732 patent/US20160130348A1/en not_active Abandoned
-
2016
- 2016-12-28 JP JP2016254558A patent/JP2017101042A/ja active Pending
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2018
- 2018-06-13 CY CY181100615T patent/CY1120626T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20180893T1 (hr) | 2018-07-27 |
| CA2833636A1 (en) | 2012-10-26 |
| RS57324B1 (sr) | 2018-08-31 |
| CN103608040A (zh) | 2014-02-26 |
| PT2699264T (pt) | 2018-05-23 |
| PL2699264T3 (pl) | 2018-08-31 |
| JP2014523401A (ja) | 2014-09-11 |
| AU2012245477C1 (en) | 2017-06-15 |
| EP2699264A4 (en) | 2014-10-08 |
| US20160130348A1 (en) | 2016-05-12 |
| SI2699264T1 (en) | 2018-08-31 |
| KR101970025B1 (ko) | 2019-04-17 |
| RU2625034C2 (ru) | 2017-07-11 |
| CN103608040B (zh) | 2017-03-01 |
| DK2699264T3 (en) | 2018-06-25 |
| CY1120626T1 (el) | 2019-12-11 |
| AU2012245477A1 (en) | 2013-10-31 |
| JP6072771B2 (ja) | 2017-02-01 |
| LT2699264T (lt) | 2018-07-10 |
| US9205148B2 (en) | 2015-12-08 |
| SMT201800294T1 (it) | 2018-07-17 |
| MX2013012088A (es) | 2014-04-30 |
| MX338353B (es) | 2016-04-13 |
| WO2012145493A1 (en) | 2012-10-26 |
| RU2013151455A (ru) | 2015-05-27 |
| EP2699264A1 (en) | 2014-02-26 |
| JP2017101042A (ja) | 2017-06-08 |
| AU2012245477B2 (en) | 2017-03-23 |
| EP2699264B1 (en) | 2018-03-14 |
| EP3403672A1 (en) | 2018-11-21 |
| HUE037651T2 (hu) | 2018-09-28 |
| KR20140048121A (ko) | 2014-04-23 |
| US20140044738A1 (en) | 2014-02-13 |
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