PL2170959T3
(pl)
|
2007-06-18 |
2014-03-31 |
Merck Sharp & Dohme |
Przeciwciała przeciwko ludzkiemu receptorowi programowanej śmierci PD-1
|
EP2262837A4
(en)
*
|
2008-03-12 |
2011-04-06 |
Merck Sharp & Dohme |
PD-1 BINDING PROTEINS
|
EP2990487A1
(en)
|
2008-05-08 |
2016-03-02 |
Asuragen, INC. |
Compositions and methods related to mirna modulation of neovascularization or angiogenesis
|
US9650639B2
(en)
|
2008-05-19 |
2017-05-16 |
Advaxis, Inc. |
Dual delivery system for heterologous antigens
|
US9017660B2
(en)
|
2009-11-11 |
2015-04-28 |
Advaxis, Inc. |
Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors
|
EP2288379A4
(en)
|
2008-05-19 |
2012-08-08 |
Advaxis |
DOUBLE RELEASE SYSTEM FOR HETEROLOGIST ANTIGENE
|
ES2592216T3
(es)
|
2008-09-26 |
2016-11-28 |
Dana-Farber Cancer Institute, Inc. |
Anticuerpos anti-PD-1, PD-L1 y PD-L2 humanos y sus usos
|
CA2756811C
(en)
|
2009-03-30 |
2014-09-23 |
Eisai R&D Management Co., Ltd. |
Liposome composition of eribulin or its pharmacologically permissible salt
|
US10016617B2
(en)
|
2009-11-11 |
2018-07-10 |
The Trustees Of The University Of Pennsylvania |
Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers
|
TW201134488A
(en)
*
|
2010-03-11 |
2011-10-16 |
Ucb Pharma Sa |
PD-1 antibodies
|
CN102892786B
(zh)
|
2010-03-11 |
2016-03-16 |
Ucb医药有限公司 |
Pd-1抗体
|
WO2012138377A2
(en)
|
2010-10-01 |
2012-10-11 |
Trustees Of The University Of Pennsylvania |
The use of listeria vaccine vectors to reverse vaccine unresponsiveness in parasitically infected individuals
|
US20140031250A1
(en)
|
2010-10-07 |
2014-01-30 |
David Tsai Ting |
Biomarkers of Cancer
|
CN103687611A
(zh)
|
2011-03-11 |
2014-03-26 |
阿德瓦希斯公司 |
基于李斯特菌属的佐剂
|
RS57324B1
(sr)
*
|
2011-04-20 |
2018-08-31 |
Medimmune Llc |
Antitela i drugi molekuli koji vezuju b7-h1 i pd-1
|
CA2834548C
(en)
|
2011-04-28 |
2021-06-01 |
The Broad Institute, Inc. |
Inhibitors of histone deacetylase
|
CN102298053B
(zh)
*
|
2011-05-20 |
2014-01-29 |
中山大学肿瘤防治中心 |
原发性肝细胞肝癌术后复发风险评估的组合抗体试剂盒
|
ES2758884T3
(es)
|
2011-06-24 |
2020-05-06 |
Stephen D Gillies |
Proteínas de fusión de inmunoglobulina a través de cadena ligera y métodos de uso de ellas
|
PL3409278T3
(pl)
|
2011-07-21 |
2021-02-22 |
Sumitomo Pharma Oncology, Inc. |
Heterocykliczne inhibitory kinazy białkowej
|
US9701749B2
(en)
|
2011-08-11 |
2017-07-11 |
Ono Pharmaceutical Co., Ltd. |
Therapeutic agent for autoimmune diseases comprising PD-1 agonist
|
EP3763741A1
(en)
|
2011-11-28 |
2021-01-13 |
Merck Patent GmbH |
Anti-pd-l1 antibodies and uses thereof
|
KR20140134695A
(ko)
|
2012-03-12 |
2014-11-24 |
어드박시스, 인크. |
리스테리아 백신 치료 후 억제 세포 기능 저해
|
US9863935B2
(en)
|
2012-05-08 |
2018-01-09 |
H. Lee Moffitt Cancer And Research Institute, Inc. |
Predictive biomarkers for CTLA-4 blockade therapy and for PD-1 blockade therapy
|
SG11201407190TA
(en)
|
2012-05-15 |
2014-12-30 |
Bristol Myers Squibb Co |
Cancer immunotherapy by disrupting pd-1/pd-l1 signaling
|
MY186099A
(en)
*
|
2012-05-31 |
2021-06-22 |
Genentech Inc |
Methods of treating cancer using pd-l1 axis binding antagonists and vegf antagonists
|
ES2618003T3
(es)
|
2012-06-13 |
2017-06-20 |
Incyte Holdings Corporation |
Compuestos tricíclicos sustituidos como inhibidores de FGFR
|
CN112587671A
(zh)
|
2012-07-18 |
2021-04-02 |
博笛生物科技有限公司 |
癌症的靶向免疫治疗
|
WO2014018979A1
(en)
|
2012-07-27 |
2014-01-30 |
The Broad Institute, Inc. |
Inhibitors of histone deacetylase
|
CN111499755A
(zh)
*
|
2012-08-03 |
2020-08-07 |
丹娜法伯癌症研究院 |
抗-pd-l1和pd-l2双结合抗体单一试剂及其使用方法
|
US10457733B2
(en)
|
2012-08-03 |
2019-10-29 |
Dana-Farber Cancer Institute, Inc. |
Agents that modulate immune cell activation and methods of use thereof
|
CA2882292C
(en)
|
2012-08-13 |
2023-10-17 |
The Rockefeller University |
Treatment and diagnosis of melanoma
|
AU2013308595C1
(en)
|
2012-08-30 |
2019-01-17 |
Amgen Inc. |
A method for treating melanoma using a herpes simplex virus and an immune checkpoint inhibitor
|
CN107892719B
(zh)
*
|
2012-10-04 |
2022-01-14 |
达纳-法伯癌症研究所公司 |
人单克隆抗-pd-l1抗体和使用方法
|
ES2707323T3
(es)
|
2012-12-07 |
2019-04-03 |
Chemocentryx Inc |
Diazol lactamas
|
AR093984A1
(es)
|
2012-12-21 |
2015-07-01 |
Merck Sharp & Dohme |
Anticuerpos que se unen a ligando 1 de muerte programada (pd-l1) humano
|
ES2739913T3
(es)
|
2013-02-22 |
2020-02-04 |
Curevac Ag |
Combinación de vacunación e inhibición de la ruta PD-1
|
EP3292873B1
(en)
|
2013-02-22 |
2019-05-01 |
CureVac AG |
Combination of vaccination and inhibition of the pd-1 pathway
|
EP3633377A1
(en)
*
|
2013-03-15 |
2020-04-08 |
F. Hoffmann-La Roche AG |
Biomarkers and methods of treating pd-1 and pd-l1 related conditions
|
US9533984B2
(en)
|
2013-04-19 |
2017-01-03 |
Incyte Holdings Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
LT2992017T
(lt)
|
2013-05-02 |
2021-02-25 |
Anaptysbio, Inc. |
Antikūnai nukreipti prieš programuotos žūties baltymą-1 (pd-1)
|
EP4119662A1
(en)
|
2013-05-10 |
2023-01-18 |
Whitehead Institute For Biomedical Research |
Protein modification of living cells using sortase
|
CN103242448B
(zh)
*
|
2013-05-27 |
2015-01-14 |
郑州大学 |
一种全人源化抗pd-1单克隆抗体及其制备方法和应用
|
CA2913977C
(en)
|
2013-05-31 |
2022-11-29 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind pd-1
|
MA38643A1
(fr)
|
2013-06-03 |
2017-10-31 |
Novartis Ag |
Combinaisons d'un anticorps anti-pd-l1 et d'un inhibiteur de mek et/ou d'un inhibiteur de braf
|
AU2014275166B2
(en)
|
2013-06-06 |
2020-09-10 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for identification, assessment prevention, and treatment of cancer using PD-L1 isoforms
|
CN104250302B
(zh)
*
|
2013-06-26 |
2017-11-14 |
上海君实生物医药科技股份有限公司 |
抗pd‑1抗体及其应用
|
BR112016002614B8
(pt)
|
2013-08-08 |
2023-10-03 |
Hopitaux Paris Assist Publique |
Imunocitoquina e composição farmacêutica
|
KR20220148304A
(ko)
|
2013-08-08 |
2022-11-04 |
싸이튠 파마 |
병용 약학 조성물
|
WO2015035606A1
(en)
*
|
2013-09-13 |
2015-03-19 |
Beigene, Ltd. |
Anti-pd1 antibodies and their use as therapeutics and diagnostics
|
US10570204B2
(en)
|
2013-09-26 |
2020-02-25 |
The Medical College Of Wisconsin, Inc. |
Methods for treating hematologic cancers
|
WO2015061668A1
(en)
*
|
2013-10-25 |
2015-04-30 |
Dana-Farber Cancer Institute, Inc. |
Anti-pd-l1 monoclonal antibodies and fragments thereof
|
NZ719232A
(en)
*
|
2013-11-05 |
2022-04-29 |
Bavarian Nordic As |
Combination therapy for treating cancer with a poxvirus expressing a tumor antigen and an antagonist and/or agonist of an immune checkpoint inhibitor
|
JP6879739B2
(ja)
|
2013-11-25 |
2021-06-02 |
フェイムウェイヴ リミテッド |
癌治療のための抗ceacam1および抗pd抗体を含む組成物
|
PL3081576T3
(pl)
|
2013-12-12 |
2020-03-31 |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
Przeciwciało anty pd-1, jego fragment wiążący antygen i ich zastosowanie medyczne
|
DE202014010499U1
(de)
|
2013-12-17 |
2015-10-20 |
Kymab Limited |
Targeting von humaner PCSK9 zur Cholesterinbehandlung
|
JP2017503503A
(ja)
*
|
2014-01-06 |
2017-02-02 |
エクスプレッション、パソロジー、インコーポレイテッド |
Pd−l1に対するsrmアッセイ
|
CN113633783A
(zh)
|
2014-01-10 |
2021-11-12 |
博笛生物科技有限公司 |
用于免疫疗法的化合物和组合物
|
AU2015206603B9
(en)
*
|
2014-01-14 |
2019-07-18 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for identification, assessment, prevention, and treatment of melanoma using PD-L1 isoforms
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對pd-1的人類抗體
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗pd-l1之人類抗體
|
JOP20200094A1
(ar)
*
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
TW201613635A
(en)
|
2014-02-04 |
2016-04-16 |
Pfizer |
Combination of a PD-1 antagonist and a 4-1BB agonist for treating cancer
|
KR20160108568A
(ko)
|
2014-02-04 |
2016-09-19 |
인사이트 코포레이션 |
암을 치료하기 위한 pd-1 길항제 및 ido1 억제제의 조합
|
HUE057205T2
(hu)
|
2014-02-04 |
2022-04-28 |
Pfizer |
PD-1 antagonista és VEGFR inhibitor kombinációja rák kezelésére
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
US10519237B2
(en)
|
2014-03-12 |
2019-12-31 |
Yeda Research And Development Co. Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
|
US10618963B2
(en)
|
2014-03-12 |
2020-04-14 |
Yeda Research And Development Co. Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
|
AU2015228372B2
(en)
|
2014-03-12 |
2018-05-31 |
Yeda Research And Development Co. Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
|
CN108025068A
(zh)
*
|
2014-03-12 |
2018-05-11 |
耶达研究与开发有限公司 |
降低系统性调节性t细胞水平或活性来治疗cns的疾病和损伤
|
US9394365B1
(en)
|
2014-03-12 |
2016-07-19 |
Yeda Research And Development Co., Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of alzheimer's disease
|
US9987258B2
(en)
|
2014-04-06 |
2018-06-05 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Histone deacetylase as a modulator of PDL1 expression and activity
|
JP6787792B2
(ja)
|
2014-05-23 |
2020-11-18 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
がんの処置のための併用治療
|
JP2017516779A
(ja)
|
2014-05-28 |
2017-06-22 |
アイデニクス・ファーマシューティカルズ・エルエルシー |
癌治療のためのヌクレオシド誘導体
|
ES2753360T3
(es)
|
2014-05-29 |
2020-04-08 |
Spring Bioscience Corp |
Anticuerpos contra PD-L1 y usos de los mismos
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
TW202136296A
(zh)
*
|
2014-06-27 |
2021-10-01 |
美商C2N醫療診斷有限責任公司 |
人類化抗-tau抗體
|
EP3160505A4
(en)
|
2014-07-03 |
2018-01-24 |
BeiGene, Ltd. |
Anti-pd-l1 antibodies and their use as therapeutics and diagnostics
|
ES2910446T3
(es)
|
2014-07-09 |
2022-05-12 |
Birdie Biopharmaceuticals Inc |
Combinaciones anti-PD-L1 para tratar tumores
|
DK3309174T3
(da)
|
2014-07-11 |
2022-06-07 |
Ventana Med Syst Inc |
ANTI-PD-L1-antistoffer og diagnostiske anvendelser deraf
|
AU2015289533B2
(en)
|
2014-07-18 |
2021-04-01 |
Advaxis, Inc. |
Combination of a PD-1 antagonist and a Listeria-based vaccine for treating prostate cancer
|
SG10201900571YA
(en)
|
2014-07-22 |
2019-02-27 |
Cb Therapeutics Inc |
Anti-pd-1 antibodies
|
CA2957258C
(en)
|
2014-08-05 |
2023-11-07 |
MabQuest SA |
Immunological reagents
|
SG10201901057UA
(en)
*
|
2014-08-05 |
2019-03-28 |
Cb Therapeutics Inc |
Anti-pd-l1 antibodies
|
US9982052B2
(en)
|
2014-08-05 |
2018-05-29 |
MabQuest, SA |
Immunological reagents
|
CA2955676A1
(en)
|
2014-08-25 |
2016-03-03 |
Pfizer Inc. |
Combination of a pd-1 antagonist and an alk inhibitor for treating cancer
|
CN112587672A
(zh)
|
2014-09-01 |
2021-04-02 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-pd-l1结合物
|
SG11201701710SA
(en)
*
|
2014-09-08 |
2017-04-27 |
Celgene Corp |
Methods for treating a disease or disorder using oral formulations of cytidine analogs in combination with an anti-pd1 or anti-pdl1 monoclonal antibody
|
EP3191126B1
(en)
|
2014-09-13 |
2020-05-13 |
Novartis AG |
Combination therapies of alk inhibitors
|
KR20230088521A
(ko)
*
|
2014-09-16 |
2023-06-19 |
이나뜨 파르마 에스.에이. |
림프구에서의 억제 경로의 중화
|
CN107074952B
(zh)
*
|
2014-09-30 |
2021-04-09 |
英特维特国际股份有限公司 |
结合犬pd-l1的pd-l1抗体
|
CA2964155A1
(en)
|
2014-10-10 |
2016-04-14 |
Idera Pharmaceuticals, Inc. |
Treatment of cancer using tlr9 agonist with checkpoint inhibitors
|
WO2016061142A1
(en)
*
|
2014-10-14 |
2016-04-21 |
Novartis Ag |
Antibody molecules to pd-l1 and uses thereof
|
EP3209321B1
(en)
|
2014-10-21 |
2021-06-23 |
SciClone Pharmaceuticals International Ltd. |
Treatment of cancer with immune stimulators
|
EP3550019A1
(en)
|
2014-10-24 |
2019-10-09 |
Astrazeneca AB |
Combination
|
WO2016073759A1
(en)
|
2014-11-05 |
2016-05-12 |
The Regents Of The University Of California |
Combination immunotherapy
|
US10822414B2
(en)
|
2014-11-11 |
2020-11-03 |
Sutro Biopharma, Inc. |
Anti-PD-1 antibodies, compositions comprising anti-PD-1 antibodies and methods of using anti-PD-1 antibodies
|
AU2015346295A1
(en)
|
2014-11-13 |
2017-05-25 |
The Johns Hopkins University |
Checkpoint blockade and microsatellite instability
|
PT3220927T
(pt)
|
2014-11-20 |
2022-02-07 |
Promega Corp |
Sistemas e métodos para avaliar moduladores de pontos de verificação imunitária
|
WO2016089833A1
(en)
|
2014-12-05 |
2016-06-09 |
Merck Sharp & Dohme Corp. |
Novel tricyclic compounds as inhibitors of mutant idh enzymes
|
US10508108B2
(en)
|
2014-12-05 |
2019-12-17 |
Merck Sharp & Dohme Corp. |
Tricyclic compounds as inhibitors of mutant IDH enzymes
|
WO2016089797A1
(en)
|
2014-12-05 |
2016-06-09 |
Merck Sharp & Dohme Corp. |
Novel tricyclic compounds as inhibitors of mutant idh enzymes
|
US20170058043A1
(en)
|
2014-12-06 |
2017-03-02 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Bispecific antibody for cancer immunotherapy
|
BR112017011982A2
(pt)
|
2014-12-09 |
2018-01-16 |
Regeneron Pharma |
roedor, polipeptídeo pd-l1, célula ou tecido isolado de roedor, célula-tronco embrionária de roedor, embrião de roedor, e, métodos para produção de um roedor, para reduzir o crescimento do tumor em um roedor, para matar células tumorais em um roedor, para avaliar as propriedades farmacocinéticas de um fármaco e para avaliar a eficácia de um fármaco.
|
TWI595006B
(zh)
*
|
2014-12-09 |
2017-08-11 |
禮納特神經系統科學公司 |
抗pd-1抗體類和使用彼等之方法
|
US20180133313A1
(en)
*
|
2014-12-16 |
2018-05-17 |
Bristol-Myers Squibb Company |
Use of immune checkpoint inhibitors in central nervous systems neoplasms
|
MA40948A
(fr)
|
2014-12-18 |
2017-10-25 |
Amgen Inc |
Formulation de virus de l'herpès simplex congelée stable
|
US11639385B2
(en)
|
2014-12-22 |
2023-05-02 |
Pd-1 Acquisition Group, Llc |
Anti-PD-1 antibodies
|
EP3916017A1
(en)
*
|
2014-12-22 |
2021-12-01 |
PD-1 Acquisition Group, LLC |
Anti-pd-1 antibodies
|
CN107428818A
(zh)
|
2015-01-29 |
2017-12-01 |
密西根州立大学校董会 |
隐藏多肽及其用途
|
EP3254110B1
(en)
|
2015-02-03 |
2020-03-18 |
Ventana Medical Systems, Inc. |
Histochemical assay for evaluating expression of programmed death ligand 1 (pd-l1)
|
EP3778604A1
(en)
*
|
2015-02-13 |
2021-02-17 |
Dana Farber Cancer Institute, Inc. |
Lrrk2 inhibitors and methods of making and using the same
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
EP3617205B1
(en)
|
2015-02-20 |
2021-08-04 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
JP6885869B2
(ja)
|
2015-02-26 |
2021-06-16 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung |
がんを治療するためのpd−1/pd−l1阻害剤
|
AU2015384801B2
(en)
|
2015-03-04 |
2022-01-06 |
Eisai R&D Management Co., Ltd. |
Combination of a PD-1 antagonist and a VEGFR/FGFR/RET tyrosine kinase inhibitor for treating cancer
|
RU2737216C2
(ru)
|
2015-03-04 |
2020-11-26 |
Мерк Шарп Энд Дохме Корп. |
Комбинация антагониста pd-1 и эрибулина для лечения рака
|
GB201503776D0
(en)
*
|
2015-03-05 |
2015-04-22 |
Pci Biotech As |
Compound and method
|
CA2978942A1
(en)
|
2015-03-13 |
2016-09-22 |
Cytomx Therapeutics, Inc. |
Anti-pdl1 antibodies, activatable anti-pdl1 antibodies, and methods of use thereof
|
US11933786B2
(en)
|
2015-03-30 |
2024-03-19 |
Stcube, Inc. |
Antibodies specific to glycosylated PD-L1 and methods of use thereof
|
CN107530429B
(zh)
|
2015-03-30 |
2021-12-07 |
斯特库比股份有限公司 |
特异性针对糖基化的pd-l1的抗体及其使用方法
|
EP3277325B1
(en)
|
2015-04-03 |
2020-10-28 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Combination immunotherapy for cancer
|
WO2016161196A1
(en)
*
|
2015-04-03 |
2016-10-06 |
Mirna Therapeutics, Inc. |
Microrna-34 immunotherapy
|
EP3277716B1
(en)
|
2015-04-03 |
2020-06-24 |
XOMA Technology Ltd. |
Treatment of cancer using inhibitors of tgf-beta and pd-1
|
EP3736287A1
(en)
|
2015-05-11 |
2020-11-11 |
The Johns Hopkins University |
Autoimmune antibodies for use in inhibiting cancer cell growth
|
CA2985194C
(en)
|
2015-05-21 |
2024-05-21 |
Chemocentryx, Inc. |
Ccr2 modulators
|
EP3303361A1
(en)
|
2015-05-27 |
2018-04-11 |
Idenix Pharmaceuticals LLC |
Nucleotides for the treatment of cancer
|
SI3303394T1
(sl)
|
2015-05-29 |
2020-10-30 |
Agenus Inc. |
Protitelesa proti-CTLA-4 in postopki njihove uporabe
|
EP3302501B1
(en)
|
2015-05-29 |
2021-09-22 |
Merck Sharp & Dohme Corp. |
Combination of a pd-1 antagonist and cpg-c type oligonucleotide for treating cancer
|
WO2016196344A1
(en)
|
2015-05-30 |
2016-12-08 |
Molecular Templates, Inc. |
De-immunized, shiga toxin a subunit scaffolds and cell-targeting molecules comprising the same
|
CA2985818A1
(en)
|
2015-05-31 |
2016-12-08 |
Curegenix Corporation |
Combination compositions comprising an antagonist of porcupine and a pd-l/pd-1 axis antagonist for immunotherapy
|
WO2016197067A1
(en)
|
2015-06-05 |
2016-12-08 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Gm-csf/cd40l vaccine and checkpoint inhibitor combination therapy
|
TWI773646B
(zh)
|
2015-06-08 |
2022-08-11 |
美商宏觀基因股份有限公司 |
結合lag-3的分子和其使用方法
|
CN106243225B
(zh)
*
|
2015-06-11 |
2021-01-19 |
智翔(上海)医药科技有限公司 |
新型抗-pd-l1抗体
|
TW201709929A
(zh)
|
2015-06-12 |
2017-03-16 |
宏觀基因股份有限公司 |
治療癌症的聯合療法
|
RU2766890C2
(ru)
|
2015-06-16 |
2022-03-16 |
Мерк Патент Гмбх |
Комбинированные способы лечения антагонистами pd-l1
|
EP4385569A2
(en)
|
2015-06-24 |
2024-06-19 |
Janssen Biotech, Inc. |
Immune modulation and treatment of solid tumors with antibodies that specifically bind cd38
|
MX2018000216A
(es)
|
2015-07-02 |
2018-05-22 |
Celgene Corp |
Terapia de combinacion para el tratamiento de canceres hematologicos y tumores solidos.
|
GB201511790D0
(en)
|
2015-07-06 |
2015-08-19 |
Iomet Pharma Ltd |
Pharmaceutical compound
|
WO2017011439A1
(en)
*
|
2015-07-13 |
2017-01-19 |
Biodesix, Inc. |
Predictive test for melanoma patient benefit from pd-1 antibody drug and classifier development methods
|
MX2018000621A
(es)
|
2015-07-13 |
2018-05-11 |
Cytomx Therapeutics Inc |
Anticuerpos anti-pd-1, anticuerpos anti-pd-1 activables, y metodos de uso de los mismos.
|
EP3744340A3
(en)
|
2015-07-16 |
2021-03-03 |
Biokine Therapeutics Ltd. |
Compositions and methods for treating cancer
|
CA2991628C
(en)
|
2015-07-16 |
2020-04-07 |
Bioxcel Therapeutics, Inc. |
A novel approach for treatment of cancer using immunomodulation
|
CN106699888B
(zh)
*
|
2015-07-28 |
2020-11-06 |
上海昀怡健康科技发展有限公司 |
一种pd-1抗体及其制备方法和应用
|
EP3456346B1
(en)
|
2015-07-30 |
2021-07-07 |
MacroGenics, Inc. |
Pd-1 and lag-3 binding molecules and methods of use thereof
|
CN106397592A
(zh)
*
|
2015-07-31 |
2017-02-15 |
苏州康宁杰瑞生物科技有限公司 |
针对程序性死亡配体(pd-l1)的单域抗体及其衍生蛋白
|
AU2016303489B2
(en)
|
2015-07-31 |
2023-02-16 |
University Of Florida Research Foundation, Inc. |
Hematopoietic stem cells in combinatorial therapy with immune checkpoint inhibitors against cancer
|
EP3331916A1
(en)
|
2015-08-04 |
2018-06-13 |
GlaxoSmithKline Intellectual Property Development Limited |
Combination treatments and uses and methods thereof
|
WO2017021911A1
(en)
|
2015-08-04 |
2017-02-09 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatments and uses and methods thereof
|
WO2017020291A1
(en)
|
2015-08-06 |
2017-02-09 |
Wuxi Biologics (Shanghai) Co. Ltd. |
Novel anti-pd-l1 antibodies
|
CN106432501B
(zh)
*
|
2015-08-06 |
2021-07-30 |
基石药业 |
新型抗pd-l1抗体
|
EP3331919A1
(en)
|
2015-08-07 |
2018-06-13 |
GlaxoSmithKline Intellectual Property Development Limited |
Combination therapy comprising anti ctla-4 antibodies
|
WO2017024465A1
(en)
*
|
2015-08-10 |
2017-02-16 |
Innovent Biologics (Suzhou) Co., Ltd. |
Pd-1 antibodies
|
US10561653B2
(en)
*
|
2015-08-11 |
2020-02-18 |
Novartis Ag |
5-bromo-2,6-di-(1H-pyrazol-1-yl)pyrimidin-4-amine for use in the treatment of cancer
|
US11453697B1
(en)
|
2015-08-13 |
2022-09-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
BR112018002757A8
(pt)
|
2015-08-13 |
2023-04-11 |
Merck Sharp & Dohme |
Composto, composição farmacêutica, e, métodos para induzir uma resposta imune, para induzir uma produção de interferon tipo i e para tratamento de um distúrbio
|
AR105654A1
(es)
|
2015-08-24 |
2017-10-25 |
Lilly Co Eli |
Anticuerpos pd-l1 (ligando 1 de muerte celular programada)
|
ES2955775T3
(es)
|
2015-08-27 |
2023-12-07 |
Inst Nat Sante Rech Med |
Métodos para predecir el tiempo de supervivencia de pacientes que padecen cáncer de pulmón
|
KR102434314B1
(ko)
|
2015-09-01 |
2022-08-19 |
아게누스 인코포레이티드 |
항-pd-1 항체 및 이를 이용하는 방법
|
US10647771B2
(en)
|
2015-09-21 |
2020-05-12 |
Merck Sharp & Dohme Corp. |
Antibody that binds to human programmed death ligand 2 (PD-L2) and uses thereof
|
WO2017055324A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of cells of monocytic origin in a tissue sample
|
WO2017055319A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of b cells in a tissue sample
|
EP3356551B1
(en)
|
2015-09-29 |
2020-09-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for determining the metabolic status of b-lymphomas
|
WO2017055327A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of endothelial cells in a tissue sample
|
WO2017055321A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of fibroblasts in a tissue sample
|
WO2017055326A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of myeloid dendritic cells in a tissue sample
|
WO2017055325A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of nk cells in a tissue sample
|
EA201890790A1
(ru)
|
2015-09-29 |
2018-10-31 |
Селджин Корпорейшн |
Связывающие pd-1 белки и способы их применения
|
WO2017055322A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of neutrophils in a tissue sample
|
WO2017055320A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of cytotoxic lymphocytes in a tissue sample
|
EP3359573B1
(en)
|
2015-10-01 |
2023-01-04 |
The Whitehead Institute for Biomedical Research |
Labeling of antibodies
|
JP2018530550A
(ja)
|
2015-10-01 |
2018-10-18 |
ギリアド サイエンシズ, インコーポレイテッド |
癌を治療するためのbtk阻害剤とチェックポイント阻害剤との組合せ
|
RU2746409C1
(ru)
*
|
2015-10-02 |
2021-04-13 |
Ф. Хоффманн-Ля Рош Аг |
Антитела к pd1 и способы их применения
|
US10287352B2
(en)
|
2015-10-02 |
2019-05-14 |
Hoffman-La Roche Inc. |
Bispecific antibodies specific for PD1 and TIM3
|
JP7320944B2
(ja)
|
2015-10-08 |
2023-08-04 |
マクロジェニクス,インコーポレーテッド |
B7‐h3に特異的に結合する分子及びpd‐1に特異的に結合する分子
|
WO2017060397A1
(en)
|
2015-10-09 |
2017-04-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of subjects suffering from melanoma metastases
|
US20180318365A1
(en)
|
2015-10-19 |
2018-11-08 |
Cold Genesys, Inc. |
Methods of treating solid or lymphatic tumors by combination therapy
|
EP4046655A1
(en)
|
2015-11-03 |
2022-08-24 |
Janssen Biotech, Inc. |
Antibodies specifically binding pd-1 and their uses
|
CA3003969A1
(en)
|
2015-11-06 |
2017-05-11 |
Orionis Biosciences Nv |
Bi-functional chimeric proteins and uses thereof
|
CN106699889A
(zh)
*
|
2015-11-18 |
2017-05-24 |
礼进生物医药科技(上海)有限公司 |
抗pd-1抗体及其治疗用途
|
US10858432B2
(en)
|
2015-12-02 |
2020-12-08 |
Stcube, Inc. |
Antibodies specific to glycosylated PD-1 and methods of use thereof
|
WO2017093933A1
(en)
|
2015-12-03 |
2017-06-08 |
Glaxosmithkline Intellectual Property Development Limited |
Cyclic purine dinucleotides as modulators of sting
|
WO2017098421A1
(en)
|
2015-12-08 |
2017-06-15 |
Glaxosmithkline Intellectual Property Development Limited |
Benzothiadiazine compounds
|
JP6955507B2
(ja)
|
2015-12-14 |
2021-10-27 |
マクロジェニクス,インコーポレーテッド |
Pd‐1及びctla‐4との免疫応答性を有する二重特異性並びにその使用方法
|
EP3389783B1
(en)
|
2015-12-15 |
2024-07-03 |
Merck Sharp & Dohme LLC |
Novel compounds as indoleamine 2,3-dioxygenase inhibitors
|
MA55194A
(fr)
|
2015-12-22 |
2022-05-04 |
Incyte Corp |
Composés hétérocycliques en tant qu'immunomodulateurs
|
CN109069597A
(zh)
|
2015-12-22 |
2018-12-21 |
诺华股份有限公司 |
间皮素嵌合抗原受体(car)和抗pd-l1抗体抑制剂联用于抗癌治疗
|
RS64588B1
(sr)
|
2015-12-22 |
2023-10-31 |
Regeneron Pharma |
Kombinacija anti-pd-1 antitela i bispecifičnih anti-cd20/anti-cd3 antitela za lečenje kancera
|
EP3400443B1
(en)
|
2016-01-04 |
2020-09-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of pd-1 and tim-3 as a measure for cd8+ cells in predicting and treating renal cell carcinoma
|
CN106943596A
(zh)
|
2016-01-07 |
2017-07-14 |
博笛生物科技(北京)有限公司 |
用于治疗肿瘤的抗-cd20组合
|
CN106943597A
(zh)
|
2016-01-07 |
2017-07-14 |
博笛生物科技(北京)有限公司 |
用于治疗肿瘤的抗-egfr组合
|
CN106943598A
(zh)
|
2016-01-07 |
2017-07-14 |
博笛生物科技(北京)有限公司 |
用于治疗肿瘤的抗-her2组合
|
CN108712904B
(zh)
|
2016-01-08 |
2022-08-02 |
细胞基因公司 |
2-(4-氯苯基)-n-((2-(2,6-二氧代哌啶-3-基)-1-氧代异吲哚啉-5-基)甲基)-2,2-二氟乙酰胺的固体形式以及其药物组合物和用途
|
AU2017205636B2
(en)
|
2016-01-08 |
2021-02-11 |
Celgene Corporation |
Antiproliferative compounds, and their pharmaceutical compositions and uses
|
AU2017205089B2
(en)
|
2016-01-08 |
2023-10-05 |
F. Hoffmann-La Roche Ag |
Methods of treating CEA-positive cancers using PD-1 axis binding antagonists and anti-CEA/anti-CD3 bispecific antibodies
|
EA037508B1
(ru)
|
2016-01-08 |
2021-04-06 |
Селджин Корпорейшн |
Композиции 2-(4-хлорфенил)-n-((2-(2,6-диоксопиперидин-3-ил)-1-оксоизоиндолин-5-ил)метил)-2,2-дифторацетамида
|
US11214617B2
(en)
|
2016-01-22 |
2022-01-04 |
MabQuest SA |
Immunological reagents
|
EP3964529A1
(en)
|
2016-01-22 |
2022-03-09 |
Mabquest SA |
Non-blocking pd1 specific antibodies
|
WO2017129763A1
(en)
|
2016-01-28 |
2017-08-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of signet ring cell gastric cancer
|
US10918737B2
(en)
|
2016-01-28 |
2021-02-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment of cancer
|
ES2924741T3
(es)
|
2016-01-28 |
2022-10-10 |
Inst Nat Sante Rech Med |
Métodos para incrementar la potencia de los inhibidores del punto de control inmunitario
|
US11710539B2
(en)
|
2016-02-01 |
2023-07-25 |
Biodesix, Inc. |
Predictive test for melanoma patient benefit from interleukin-2 (IL2) therapy
|
EP3411407B1
(en)
|
2016-02-05 |
2024-04-03 |
Orionis Biosciences BV |
Bispecific signaling agents and uses thereof
|
BR112018015690A2
(pt)
|
2016-02-17 |
2018-12-26 |
Novartis Ag |
anticorpos tgfbeta 2
|
EP3419999B1
(en)
|
2016-02-26 |
2021-08-04 |
(INSERM) Institut National de la Santé et de la Recherche Médicale |
Antibodies having specificity for btla and uses thereof
|
WO2017148424A1
(zh)
|
2016-03-04 |
2017-09-08 |
四川科伦博泰生物医药股份有限公司 |
一种pdl-1抗体、其药物组合物及其用途
|
WO2017153952A1
(en)
|
2016-03-10 |
2017-09-14 |
Glaxosmithkline Intellectual Property Development Limited |
5-sulfamoyl-2-hydroxybenzamide derivatives
|
US11497781B2
(en)
|
2016-03-10 |
2022-11-15 |
Cg Oncology, Inc. |
Methods of treating bladder cancer by combination therapy comprising the oncolytic adenovirus CG0070 and an immune checkpoint inhibitor
|
WO2017160599A1
(en)
|
2016-03-14 |
2017-09-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Use of cd300b antagonists to treat sepsis and septic shock
|
US10947317B2
(en)
|
2016-03-15 |
2021-03-16 |
Mersana Therapeutics, Inc. |
NaPi2b-targeted antibody-drug conjugates and methods of use thereof
|
US11760803B2
(en)
|
2016-03-24 |
2023-09-19 |
Takeda Pharmaceutical Company Limited |
Methods of treating gastrointestinal immune-related adverse events in immune oncology treatments
|
TW201735949A
(zh)
|
2016-03-24 |
2017-10-16 |
千禧製藥公司 |
治療抗ctla4及抗pd-1組合治療中的胃腸道免疫相關不良事件之方法
|
US11660352B2
(en)
|
2016-03-29 |
2023-05-30 |
Stcube, Inc. |
Dual function antibodies specific to glycosylated PD-L1 and methods of use thereof
|
KR20230031373A
(ko)
|
2016-03-29 |
2023-03-07 |
주식회사 에스티큐브앤컴퍼니 |
글리코실화된 면역체크포인트 단백질에 특이적으로 결합하는 항체를 선택하는 방법
|
CN109608443B
(zh)
|
2016-04-07 |
2021-09-07 |
葛兰素史密斯克莱知识产权发展有限公司 |
用作蛋白质调节剂的杂环酰胺
|
KR102370704B1
(ko)
|
2016-04-07 |
2022-03-03 |
케모센트릭스, 인크. |
Pd-1 억제제 또는 pd-l1 억제제와 조합하여 ccr1 길항제를 투여하여 종양 총량을 감소시키는 방법
|
EP3440072B1
(en)
|
2016-04-07 |
2020-01-29 |
GlaxoSmithKline Intellectual Property Development Ltd |
Heterocyclic amides useful as protein modulators
|
KR102548385B1
(ko)
*
|
2016-04-14 |
2023-06-28 |
크리에티브이 마이크로테크, 인크. |
암 요법을 위한 치료 결정에서 pd-l1 발현을 사용하는 방법
|
EP3449921B1
(en)
|
2016-04-28 |
2023-05-31 |
Eisai R&D Management Co., Ltd. |
Eribulin for inhibiting tumor growth
|
JP7280821B2
(ja)
|
2016-05-05 |
2023-05-24 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
チェックポイント分子を標的とするdnaモノクロナール抗体
|
WO2017191545A1
(en)
|
2016-05-05 |
2017-11-09 |
Glaxosmithkline Intellectual Property (No.2) Limited |
Enhancer of zeste homolog 2 inhibitors
|
TWI822521B
(zh)
|
2016-05-13 |
2023-11-11 |
美商再生元醫藥公司 |
藉由投予pd-1抑制劑治療皮膚癌之方法
|
WO2017194782A2
(en)
|
2016-05-13 |
2017-11-16 |
Orionis Biosciences Nv |
Therapeutic targeting of non-cellular structures
|
EP3243832A1
(en)
|
2016-05-13 |
2017-11-15 |
F. Hoffmann-La Roche AG |
Antigen binding molecules comprising a tnf family ligand trimer and pd1 binding moiety
|
CN109689087B
(zh)
|
2016-05-13 |
2023-04-04 |
奥里尼斯生物科学私人有限公司 |
靶向性突变干扰素-β及其用途
|
CN105968200B
(zh)
*
|
2016-05-20 |
2019-03-15 |
瑞阳(苏州)生物科技有限公司 |
抗人pd-l1人源化单克隆抗体及其应用
|
WO2017202962A1
(en)
|
2016-05-24 |
2017-11-30 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of non small cell lung cancer (nsclc) that coexists with chronic obstructive pulmonary disease (copd)
|
BR112018074192A8
(pt)
|
2016-05-25 |
2022-11-22 |
Inst Nat Sante Rech Med |
Método para tratamento de um sujeito, método para produzir uma composição celular, composição de células, composição de vacina e kit
|
EP3464360A1
(en)
|
2016-05-27 |
2019-04-10 |
Agenus Inc. |
Anti-tim-3 antibodies and methods of use thereof
|
AU2017279029A1
(en)
|
2016-06-08 |
2018-12-20 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds as ATF4 pathway inhibitors
|
WO2017212423A1
(en)
|
2016-06-08 |
2017-12-14 |
Glaxosmithkline Intellectual Property Development Limited |
Chemcical compounds
|
EP3468581A1
(en)
|
2016-06-13 |
2019-04-17 |
Torque Therapeutics, Inc. |
Methods and compositions for promoting immune cell function
|
US9567399B1
(en)
|
2016-06-20 |
2017-02-14 |
Kymab Limited |
Antibodies and immunocytokines
|
WO2018029474A2
(en)
|
2016-08-09 |
2018-02-15 |
Kymab Limited |
Anti-icos antibodies
|
IL263825B
(en)
|
2016-06-20 |
2022-08-01 |
Incyte Corp |
Heterocyclic compounds as immunomodulators
|
AU2017281830B2
(en)
|
2016-06-20 |
2023-04-06 |
Kymab Limited |
Anti-PD-L1 antibodies
|
SG11201811237WA
(en)
|
2016-06-24 |
2019-01-30 |
Infinity Pharmaceuticals Inc |
Combination therapies
|
RU2758007C2
(ru)
|
2016-06-30 |
2021-10-25 |
Онкорус, Инк. |
Доставка терапевтических полипептидов посредством псевдотипированных онколитических вирусов
|
WO2018007885A1
(en)
|
2016-07-05 |
2018-01-11 |
Beigene, Ltd. |
COMBINATION OF A PD-l ANTAGONIST AND A RAF INHIBITOR FOR TREATING CANCER
|
EA201990230A1
(ru)
|
2016-07-07 |
2019-07-31 |
Айовэнс Байотерапьютикс, Инк. |
Белки, связывающие лиганд 1 запрограммированной смерти 1 (pd-l1), и способы их использования
|
WO2018011166A2
(en)
|
2016-07-12 |
2018-01-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of myeloid dendritic cells in a tissue sample
|
US20190233534A1
(en)
|
2016-07-14 |
2019-08-01 |
Fred Hutchinson Cancer Research Center |
Multiple bi-specific binding domain constructs with different epitope binding to treat cancer
|
EP3487503A1
(en)
|
2016-07-20 |
2019-05-29 |
GlaxoSmithKline Intellectual Property Development Limited |
Isoquinoline derivatives as perk inhibitors
|
US11746152B2
(en)
|
2016-07-20 |
2023-09-05 |
Stcube, Inc. |
Methods of cancer treatment and therapy using a combination of antibodies that bind glycosylated PD-L1
|
WO2018025221A1
(en)
|
2016-08-04 |
2018-02-08 |
Glaxosmithkline Intellectual Property Development Limited |
Anti-icos and anti-pd-1 antibody combination therapy
|
EP3497128A2
(en)
|
2016-08-09 |
2019-06-19 |
Kymab Limited |
Anti-icos antibodies
|
WO2018029336A1
(en)
|
2016-08-12 |
2018-02-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for determining whether a subject was administered with an activator of the ppar beta/delta pathway.
|
CA3034326A1
(en)
|
2016-08-19 |
2018-02-22 |
Beigene, Ltd. |
Use of a combination comprising a btk inhibitor for treating cancers
|
CN106967172B
(zh)
|
2016-08-23 |
2019-01-08 |
康方药业有限公司 |
抗ctla4-抗pd-1 双功能抗体、其药物组合物及其用途
|
WO2018035710A1
(en)
|
2016-08-23 |
2018-03-01 |
Akeso Biopharma, Inc. |
Anti-ctla4 antibodies
|
CN106977602B
(zh)
*
|
2016-08-23 |
2018-09-25 |
中山康方生物医药有限公司 |
一种抗pd1单克隆抗体、其药物组合物及其用途
|
JP7045378B2
(ja)
|
2016-09-01 |
2022-03-31 |
キメラ・バイオエンジニアリング,インコーポレーテッド |
Gold最適化CAR T細胞
|
WO2018046738A1
(en)
|
2016-09-12 |
2018-03-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of patients suffering from cancer
|
WO2018046736A1
(en)
|
2016-09-12 |
2018-03-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of patients suffering from cancer
|
CN109789205B
(zh)
|
2016-09-14 |
2022-12-13 |
艾伯维生物制药股份有限公司 |
抗pd-1(cd279)抗体
|
SG11201901950TA
(en)
|
2016-09-19 |
2019-04-29 |
Celgene Corp |
Methods of treating immune disorders using pd-1 binding proteins
|
JP2019534859A
(ja)
|
2016-09-19 |
2019-12-05 |
セルジーン コーポレイション |
Pd−1結合タンパク質を使用して白斑を治療する方法
|
US11524988B2
(en)
|
2016-09-19 |
2022-12-13 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Artificial antigen presenting cells for genetic engineering of immune cells
|
EP3515453A1
(en)
|
2016-09-22 |
2019-07-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for reprograming immune environment in a subject in need thereof
|
MY196383A
(en)
|
2016-10-04 |
2023-03-28 |
Merck Sharp & Dohme Llc |
Benzo[B]Thiophene Compounds As Sting Agonists
|
MX2019003755A
(es)
|
2016-10-06 |
2019-08-12 |
Pfizer |
Regimen de dosificacion de avelumab para el tratamiento de cancer.
|
EP3522932A4
(en)
|
2016-10-10 |
2020-06-24 |
Cellerant Therapeutics, Inc. |
ISOCHINOLIDINOBENZODIAZEPINE (IQB) -1 (CHLORMETHYL) -2,3-DIHYDRO-1-H-BENZO [E] INDOL (CBI) DIMERS
|
CN117586403A
(zh)
|
2016-10-11 |
2024-02-23 |
艾吉纳斯公司 |
抗lag-3抗体及其使用方法
|
US20190263927A1
(en)
|
2016-10-14 |
2019-08-29 |
Merck Sharp & Dohme Corp. |
Combination of a pd-1 antagonist and eribulin for treating urothelial cancer
|
CA3084459A1
(en)
|
2016-10-16 |
2018-04-19 |
Cellerant Therapeutics, Inc. |
Anti-il1-rap antibodies
|
WO2018071910A2
(en)
*
|
2016-10-16 |
2018-04-19 |
Cellerant Therapeutics, Inc. |
Anti-il1-rap antibodies
|
WO2018075447A1
(en)
|
2016-10-19 |
2018-04-26 |
The Trustees Of Columbia University In The City Of New York |
Combination of braf inhibitor, talimogene laherparepvec, and immune checkpoint inhibitor for use in the treatment cancer (melanoma)
|
JP7204643B2
(ja)
|
2016-10-24 |
2023-01-16 |
オリオニス バイオサイエンシズ ビーブイ |
標的変異インターフェロン-ガンマおよびその使用
|
CN110049777A
(zh)
|
2016-11-01 |
2019-07-23 |
安奈普泰斯生物有限公司 |
针对程序性死亡-1(pd-1)的抗体
|
UY37463A
(es)
|
2016-11-02 |
2018-05-31 |
Glaxosmithkline Ip No 2 Ltd |
Proteínas de unión
|
US11779604B2
(en)
|
2016-11-03 |
2023-10-10 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses and methods
|
US10342785B2
(en)
|
2016-11-04 |
2019-07-09 |
Askat Inc. |
Use of EP4 receptor antagonists for the treatment of NASH-associated liver cancer
|
WO2018089688A1
(en)
|
2016-11-09 |
2018-05-17 |
Jinjun Shi |
Restoration of tumor suppression using mrna-based delivery system
|
WO2018087391A1
(en)
|
2016-11-14 |
2018-05-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for modulating stem cells proliferation or differentiation
|
US11279694B2
(en)
|
2016-11-18 |
2022-03-22 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
WO2018091542A1
(en)
|
2016-11-21 |
2018-05-24 |
Idenix Pharmaceuticals Llc |
Cyclic phosphate substituted nucleoside derivatives for the treatment of liver diseases
|
WO2018098352A2
(en)
|
2016-11-22 |
2018-05-31 |
Jun Oishi |
Targeting kras induced immune checkpoint expression
|
US11135307B2
(en)
|
2016-11-23 |
2021-10-05 |
Mersana Therapeutics, Inc. |
Peptide-containing linkers for antibody-drug conjugates
|
CN110248676A
(zh)
|
2016-12-01 |
2019-09-17 |
葛兰素史密斯克莱知识产权发展有限公司 |
组合疗法
|
WO2018100535A1
(en)
|
2016-12-01 |
2018-06-07 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapy
|
EP3551225A1
(en)
|
2016-12-07 |
2019-10-16 |
Agenus Inc. |
Antibodies and methods of use thereof
|
SG10201912560YA
(en)
|
2016-12-07 |
2020-02-27 |
Agenus Inc |
Anti-ctla-4 antibodies and methods of use thereof
|
CA3046963A1
(en)
|
2016-12-14 |
2018-06-21 |
Janssen Biotech, Inc. |
Cd8a-binding fibronectin type iii domains
|
US10611823B2
(en)
|
2016-12-14 |
2020-04-07 |
Hanssen Biotech, Inc |
CD137 binding fibronectin type III domains
|
US10597438B2
(en)
|
2016-12-14 |
2020-03-24 |
Janssen Biotech, Inc. |
PD-L1 binding fibronectin type III domains
|
MY197635A
(en)
|
2016-12-22 |
2023-06-29 |
Incyte Corp |
Benzooxazole derivatives as immunomodulators
|
CN110869052A
(zh)
|
2016-12-23 |
2020-03-06 |
维图生物制剂公司 |
癌症的治疗
|
CN106957823A
(zh)
*
|
2016-12-28 |
2017-07-18 |
无锡傲锐东源生物科技有限公司 |
抗pd‑l2蛋白单克隆抗体及其用途
|
WO2018122249A1
(en)
|
2016-12-28 |
2018-07-05 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of patients suffering from a microsatellite stable colorectal cancer
|
WO2018122245A1
(en)
|
2016-12-28 |
2018-07-05 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of predicting the survival time of patients suffering from cms3 colorectal cancer
|
CN116884477A
(zh)
|
2017-01-05 |
2023-10-13 |
佰欧迪塞克斯公司 |
用于鉴定总体不良预后亚组中持久受益于免疫疗法的癌症患者的方法
|
EP3565842A1
(en)
|
2017-01-06 |
2019-11-13 |
Crescendo Biologics Limited |
Single domain antibodies to programmed cell death (pd-1)
|
BR112019014187A2
(pt)
|
2017-01-09 |
2020-02-11 |
Tesaro, Inc. |
Métodos de tratamento de câncer com anticorpos anti-pd-1
|
EA201991696A1
(ru)
|
2017-01-13 |
2020-02-05 |
Эйдженус Инк. |
Т-клеточные рецепторы, связывающиеся с ny-eso-1, и способы их применения
|
EP3570870A1
(en)
|
2017-01-20 |
2019-11-27 |
Novartis AG |
Combination therapy for the treatment of cancer
|
CN110382536B
(zh)
|
2017-01-20 |
2023-12-19 |
大有华夏生物医药集团有限公司 |
抗pd-1抗体及其用途
|
US11555038B2
(en)
|
2017-01-25 |
2023-01-17 |
Beigene, Ltd. |
Crystalline forms of (S)-7-(1-(but-2-ynoyl)piperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, preparation, and uses thereof
|
US10434095B2
(en)
|
2017-01-27 |
2019-10-08 |
Celgene Corporation |
3-(1-oxo-4-((4-((3-oxomorpholino)methyl)benzyl)oxy)isoindolin-2-yl)piperidine-2,6-dione and isotopologues thereof
|
AU2018216032B2
(en)
|
2017-02-06 |
2022-04-07 |
Orionis Biosciences BV |
Targeted chimeric proteins and uses thereof
|
CN110573172A
(zh)
|
2017-02-06 |
2019-12-13 |
奥里尼斯生物科学有限公司 |
靶向的工程化干扰素及其用途
|
WO2018146148A1
(en)
|
2017-02-07 |
2018-08-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
A method for predicting the response to checkpoint blockade cancer immunotherapy
|
WO2018146128A1
(en)
|
2017-02-07 |
2018-08-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Detection of kit polymorphism for predicting the response to checkpoint blockade cancer immunotherapy
|
JP7161481B2
(ja)
|
2017-02-10 |
2022-10-26 |
ノバルティス アーゲー |
1-(4-アミノ-5-ブロモ-6-(1h-ピラゾール-1-イル)ピリミジン-2-イル)-1h-ピラゾール-4-オール及びがんの治療におけるその使用
|
WO2018150326A1
(en)
|
2017-02-15 |
2018-08-23 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatment for cancer
|
EP3585403A4
(en)
|
2017-02-22 |
2020-12-09 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
CHEMERICAL ANTIGENIC RECEPTORS BINDING TO TIM3
|
EP3585431A4
(en)
|
2017-02-24 |
2020-12-16 |
MacroGenics, Inc. |
BISPECIFIC BINDING MOLECULES CAPABLE OF BINDING TO CD137 AND TUMOR ANTIGENS, AND THEIR USES
|
EP3585782A1
(en)
|
2017-02-27 |
2020-01-01 |
GlaxoSmithKline Intellectual Property Development Limited |
Heterocyclic amides as kinase inhibitors
|
WO2018160538A1
(en)
|
2017-02-28 |
2018-09-07 |
Mersana Therapeutics, Inc. |
Combination therapies of her2-targeted antibody-drug conjugates
|
WO2018162749A1
(en)
|
2017-03-09 |
2018-09-13 |
Genmab A/S |
Antibodies against pd-l1
|
WO2018167780A1
(en)
|
2017-03-12 |
2018-09-20 |
Yeda Research And Development Co. Ltd. |
Methods of prognosing and treating cancer
|
EP3596469A1
(en)
|
2017-03-12 |
2020-01-22 |
Yeda Research and Development Co., Ltd. |
Methods of diagnosing and prognosing cancer
|
CA3056392A1
(en)
|
2017-03-15 |
2018-09-20 |
Amgen Inc. |
Use of oncolytic viruses, alone or in combination with a checkpoint inhibitor, for the treatment of cancer
|
US20210186982A1
(en)
|
2017-03-24 |
2021-06-24 |
Universite Nice Sophia Antipolis |
Methods and compositions for treating melanoma
|
KR102644408B1
(ko)
|
2017-03-30 |
2024-03-07 |
메르크 파텐트 게엠베하 |
암의 치료를 위한 항-pd-l1 항체 및 dna-pk 억제제의 병용
|
MA49033B1
(fr)
|
2017-04-03 |
2022-10-31 |
Hoffmann La Roche |
Immunoconjugué d'un anticorps contre pd-1 avec il-2 mutée ou avec il-15
|
UA128451C2
(uk)
|
2017-04-05 |
2024-07-17 |
Ф. Хоффманн-Ля Рош Аг |
Біспецифічне антитіло, яке специфічно зв'язується з pd1 і lag3
|
US11603407B2
(en)
|
2017-04-06 |
2023-03-14 |
Regeneron Pharmaceuticals, Inc. |
Stable antibody formulation
|
MX2019012223A
(es)
|
2017-04-13 |
2019-12-09 |
Agenus Inc |
Anticuerpos anti-cd137 y metodos de uso de los mismos.
|
RU2665790C1
(ru)
|
2017-04-17 |
2018-09-04 |
Закрытое Акционерное Общество "Биокад" |
Моноклональное антитело к pd-l1
|
CN108728444A
(zh)
|
2017-04-18 |
2018-11-02 |
长春华普生物技术股份有限公司 |
免疫调节性多核苷酸及其应用
|
CA3060554A1
(en)
|
2017-04-18 |
2018-10-25 |
Tempest Therapeutics, Inc. |
Bicyclic compounds and their use in the treatment of cancer
|
CN107090042B
(zh)
*
|
2017-04-25 |
2019-03-12 |
福州大学 |
一种人源程序性死亡因子配体hPD-L2单克隆抗体
|
CN108794467A
(zh)
|
2017-04-27 |
2018-11-13 |
博笛生物科技有限公司 |
2-氨基-喹啉衍生物
|
AR111651A1
(es)
|
2017-04-28 |
2019-08-07 |
Novartis Ag |
Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación
|
AU2018263857A1
(en)
|
2017-05-01 |
2019-11-21 |
Agenus Inc. |
Anti-TIGIT antibodies and methods of use thereof
|
US11466047B2
(en)
|
2017-05-12 |
2022-10-11 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
AR111760A1
(es)
|
2017-05-19 |
2019-08-14 |
Novartis Ag |
Compuestos y composiciones para el tratamiento de tumores sólidos mediante administración intratumoral
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
JOP20190279A1
(ar)
|
2017-05-31 |
2019-11-28 |
Novartis Ag |
الصور البلورية من 5-برومو -2، 6-داي (1h-بيرازول -1-يل) بيريميدين -4- أمين وأملاح جديدة
|
JP2020522486A
(ja)
|
2017-06-01 |
2020-07-30 |
サイトメックス セラピューティクス インコーポレイテッド |
活性化可能抗pdl1抗体、およびその使用方法
|
WO2018222989A1
(en)
|
2017-06-02 |
2018-12-06 |
The Penn State Research Foundation |
Ceramide nanoliposomes, compositions and methods of using for immunotherapy
|
WO2018225093A1
(en)
|
2017-06-07 |
2018-12-13 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds as atf4 pathway inhibitors
|
CN110869049A
(zh)
|
2017-06-09 |
2020-03-06 |
葛兰素史克知识产权开发有限公司 |
组合疗法
|
EP3634584A4
(en)
|
2017-06-09 |
2021-04-07 |
Providence Health & Services - Oregon |
USE OF CD39 AND CD103 FOR THE IDENTIFICATION OF REACTIVE HUMAN TUMOR CELLS FOR THE TREATMENT OF CANCER
|
WO2018229715A1
(en)
|
2017-06-16 |
2018-12-20 |
Novartis Ag |
Compositions comprising anti-cd32b antibodies and methods of use thereof
|
CN107083398A
(zh)
*
|
2017-06-16 |
2017-08-22 |
深圳惠升生物科技有限公司 |
植物作为宿主在表达pd‑1抗体和/或pd‑l1抗体中的应用
|
GB201709808D0
(en)
|
2017-06-20 |
2017-08-02 |
Kymab Ltd |
Antibodies
|
CN111032025A
(zh)
|
2017-06-20 |
2020-04-17 |
居里研究所 |
Suv39h1组蛋白甲基转移酶的抑制剂在癌症联合治疗中的用途
|
US20190048072A1
(en)
|
2017-06-22 |
2019-02-14 |
Novartis Ag |
USE OF IL-1beta BINDING ANTIBODIES
|
US20200172628A1
(en)
|
2017-06-22 |
2020-06-04 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
BR112019027402A2
(pt)
|
2017-06-22 |
2020-07-07 |
Celgene Corporation |
tratamento de carcinoma hepatocelular caracterizado por infecção pelo vírus da hepatite b
|
EA202090104A1
(ru)
|
2017-06-22 |
2020-04-09 |
Новартис Аг |
Молекулы антител к cd73 и пути их применения
|
WO2018235056A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
IL-1BETA BINDING ANTIBODIES FOR USE IN THE TREATMENT OF CANCER
|
CN110769827A
(zh)
|
2017-06-23 |
2020-02-07 |
博笛生物科技有限公司 |
药物组合物
|
KR20200020902A
(ko)
|
2017-06-26 |
2020-02-26 |
베이진 엘티디 |
간세포암(hepatocellular carcinoma: HCC)에 대한 면역 치료
|
EP3645037A1
(en)
|
2017-06-27 |
2020-05-06 |
Novartis AG |
Dosage regimens for anti-tim-3 antibodies and uses thereof
|
AU2018294327A1
(en)
|
2017-06-30 |
2020-01-23 |
Celgene Corporation |
Compositions and methods of use of 2-(4-chlorophenyl)-N-((2-(2,6-doxopiperidin-3-yl)-1-oxoisoindolin-5-yl) methyl) -2,2-difluoroacetamide
|
CA3068753A1
(en)
|
2017-07-03 |
2019-01-10 |
Glaxosmithkline Intellectual Property Development Limited |
N-(3-(2-(4-chlorophenoxy)acetamido)bicyclo[1.1.1]pentan-1-yl)-2-cyclobutane-1-carboxamide derivatives and related compounds as atf4 inhibitors for treating cancer and other diseases
|
WO2019008507A1
(en)
|
2017-07-03 |
2019-01-10 |
Glaxosmithkline Intellectual Property Development Limited |
2- (4-CHLOROPHENOXY) -N - ((1- (2- (4-CHLOROPHENOXY) ETHYNAZETIDIN-3-YL) METHYL) ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF ATF4 FOR THE TREATMENT OF CANCER AND D OTHER DISEASES
|
TWI830576B
(zh)
|
2017-07-10 |
2024-01-21 |
美商西建公司 |
抗增生化合物及其使用方法
|
EP3655023A1
(en)
|
2017-07-20 |
2020-05-27 |
Novartis AG |
Dosage regimens of anti-lag-3 antibodies and uses thereof
|
WO2019017420A1
(ja)
*
|
2017-07-20 |
2019-01-24 |
国立大学法人北海道大学 |
Pd-1/pd-l1を標的とする阻害薬とcox-2阻害薬との併用
|
EP3658173A1
(en)
|
2017-07-25 |
2020-06-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for modulating monocytopoiesis
|
WO2019021208A1
(en)
|
2017-07-27 |
2019-01-31 |
Glaxosmithkline Intellectual Property Development Limited |
USEFUL INDAZOLE DERIVATIVES AS PERK INHIBITORS
|
US11312772B2
(en)
|
2017-08-04 |
2022-04-26 |
Merck Sharp & Dohme Corp. |
Combinations of PD-1 antagonists and benzo [b] thiophene STING agonists for cancer treatment
|
JP2020530838A
(ja)
|
2017-08-04 |
2020-10-29 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
がん治療のためのベンゾ[b]チオフェンSTINGアゴニスト
|
KR20200064062A
(ko)
|
2017-08-04 |
2020-06-05 |
젠맵 에이/에스 |
Pd-l1 및 cd137에 결합하는 결합제 및 그의 용도
|
EP3679062A1
(en)
|
2017-09-04 |
2020-07-15 |
Agenus Inc. |
T cell receptors that bind to mixed lineage leukemia (mll)-specific phosphopeptides and methods of use thereof
|
TW201922721A
(zh)
|
2017-09-07 |
2019-06-16 |
英商葛蘭素史克智慧財產發展有限公司 |
化學化合物
|
WO2019051164A1
(en)
|
2017-09-07 |
2019-03-14 |
Augusta University Research Institute, Inc. |
ANTIBODIES AGAINST PROTEIN 1 OF PROGRAMMED CELL DEATH
|
US11497756B2
(en)
|
2017-09-12 |
2022-11-15 |
Sumitomo Pharma Oncology, Inc. |
Treatment regimen for cancers that are insensitive to BCL-2 inhibitors using the MCL-1 inhibitor alvocidib
|
WO2019053617A1
(en)
|
2017-09-12 |
2019-03-21 |
Glaxosmithkline Intellectual Property Development Limited |
CHEMICAL COMPOUNDS
|
US20210060158A1
(en)
|
2017-09-19 |
2021-03-04 |
Institut Curie |
Agonist of aryl hydrocarbon receptor for use in cancer combination therapy
|
MA50665A
(fr)
|
2017-09-25 |
2020-08-05 |
Chemocentryx Inc |
Polythérapie utilisant un antagoniste du récepteur 2 de la chimiokine (ccr2) et un inhibiteur pd-1/pd-l1
|
EA039662B1
(ru)
|
2017-10-03 |
2022-02-24 |
Закрытое Акционерное Общество "Биокад" |
Антитела, специфичные к cd47 и pd-l1
|
TW201927771A
(zh)
|
2017-10-05 |
2019-07-16 |
英商葛蘭素史密斯克藍智慧財產發展有限公司 |
可作為蛋白質調節劑之雜環醯胺及其使用方法
|
BR112020006780A2
(pt)
|
2017-10-05 |
2020-10-06 |
Glaxosmithkline Intellectual Property Development Limited |
moduladores do estimulador de genes do interferon (sting)
|
WO2019077132A1
(en)
|
2017-10-19 |
2019-04-25 |
Debiopharm International S.A. |
COMBINATION PRODUCT FOR THE TREATMENT OF CANCER
|
WO2019083971A1
(en)
|
2017-10-23 |
2019-05-02 |
Children's Medical Center Corporation |
METHODS OF TREATING CANCER USING LSD1 INHIBITORS IN COMBINATION WITH IMMUNOTHERAPY
|
EP3700933A1
(en)
|
2017-10-25 |
2020-09-02 |
Novartis AG |
Antibodies targeting cd32b and methods of use thereof
|
US20210179607A1
(en)
|
2017-11-01 |
2021-06-17 |
Merck Sharp & Dohme Corp. |
Novel substituted tetrahydroquinolin compounds as indoleamine 2,3-dioxygenase (ido) inhibitors
|
ES2948307T3
(es)
|
2017-11-14 |
2023-09-08 |
Merck Sharp & Dohme Llc |
Nuevos compuestos de biarilo sustituidos como inhibidores de indolamina 2,3-dioxigenasa (IDO)
|
US11498904B2
(en)
|
2017-11-14 |
2022-11-15 |
Merck Sharp & Dohme Llc |
Substituted biaryl compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors
|
RU2020119578A
(ru)
|
2017-11-16 |
2021-12-17 |
Новартис Аг |
Комбинированные терапии
|
KR20200111168A
(ko)
|
2017-11-24 |
2020-09-28 |
인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) |
암 치료를 위한 방법 및 조성물
|
WO2019104289A1
(en)
|
2017-11-27 |
2019-05-31 |
Mersana Therapeutics, Inc. |
Pyrrolobenzodiazepine antibody conjugates
|
WO2019108795A1
(en)
|
2017-11-29 |
2019-06-06 |
Beigene Switzerland Gmbh |
Treatment of indolent or aggressive b-cell lymphomas using a combination comprising btk inhibitors
|
US20200371091A1
(en)
|
2017-11-30 |
2020-11-26 |
Novartis Ag |
Bcma-targeting chimeric antigen receptor, and uses thereof
|
US11629189B2
(en)
|
2017-12-19 |
2023-04-18 |
Kymab Limited |
Bispecific antibody for ICOS and PD-L1
|
GB201721338D0
(en)
|
2017-12-19 |
2018-01-31 |
Kymab Ltd |
Anti-icos Antibodies
|
US11685761B2
(en)
|
2017-12-20 |
2023-06-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
TW201929908A
(zh)
|
2017-12-21 |
2019-08-01 |
美商梅爾莎納醫療公司 |
吡咯并苯并二氮呯抗體共軛物
|
CN111542543B
(zh)
*
|
2017-12-28 |
2023-12-22 |
南京传奇生物科技有限公司 |
针对pd-l1的抗体及其变体
|
US11865081B2
(en)
|
2017-12-29 |
2024-01-09 |
Virogin Biotech Canada Ltd. |
Oncolytic viral delivery of therapeutic polypeptides
|
EP3735590A1
(en)
|
2018-01-04 |
2020-11-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma resistant
|
EP3737367A4
(en)
|
2018-01-08 |
2022-11-09 |
ChemoCentryx, Inc. |
METHODS OF TREATING SOLID TUMORS USING CCR2 ANTAGONISTS
|
JP7281824B2
(ja)
|
2018-01-08 |
2023-05-26 |
エイチ リー モフィット キャンサー センター アンド リサーチ インスティテュート インコーポレイテッド |
Cd99-発現癌を標的にするための組成物および方法
|
EP3737408A1
(en)
|
2018-01-08 |
2020-11-18 |
Novartis AG |
Immune-enhancing rnas for combination with chimeric antigen receptor therapy
|
US11713446B2
(en)
|
2018-01-08 |
2023-08-01 |
Iovance Biotherapeutics, Inc. |
Processes for generating TIL products enriched for tumor antigen-specific T-cells
|
US20190269664A1
(en)
|
2018-01-08 |
2019-09-05 |
Chemocentryx, Inc. |
Methods of treating solid tumors with ccr2 antagonists
|
JP7315244B2
(ja)
|
2018-01-09 |
2023-07-26 |
エイチ リー モフィット キャンサー センター アンド リサーチ インスティテュート インコーポレイテッド |
Clec12a発現癌を標的にするための組成物および方法
|
US11359021B2
(en)
*
|
2018-01-10 |
2022-06-14 |
Jiangsu Hengrui Medicine Co., Ltd. |
PD-L1 antibody, antigen-binding fragment thereof, and pharmaceutical use thereof
|
CA3125731A1
(en)
|
2018-01-12 |
2019-07-18 |
KDAc Therapeutics, Inc. |
Combination of a selective histone deacetylase 3 (hdac3) inhibitor and an immunotherapy agent for the treatment of cancer
|
EP3746116A1
(en)
|
2018-01-31 |
2020-12-09 |
Novartis AG |
Combination therapy using a chimeric antigen receptor
|
US20200354457A1
(en)
|
2018-01-31 |
2020-11-12 |
Hoffmann-La Roche Inc. |
Bispecific antibodies comprising an antigen-binding site binding to lag3
|
MA54118A
(fr)
|
2018-01-31 |
2021-09-15 |
Celgene Corp |
Polythérapie utilisant une thérapie cellulaire adoptive et un inhibiteur de point de contrôle
|
CA3090406A1
(en)
|
2018-02-05 |
2019-08-08 |
Orionis Biosciences, Inc. |
Fibroblast binding agents and use thereof
|
WO2019157087A1
(en)
|
2018-02-06 |
2019-08-15 |
The General Hospital Corporation |
Repeat rna as biomarkers of tumor immune response
|
US20200399383A1
(en)
|
2018-02-13 |
2020-12-24 |
Novartis Ag |
Chimeric antigen receptor therapy in combination with il-15r and il15
|
WO2019158645A1
(en)
|
2018-02-14 |
2019-08-22 |
Abba Therapeutics Ag |
Anti-human pd-l2 antibodies
|
GB201802573D0
(en)
|
2018-02-16 |
2018-04-04 |
Crescendo Biologics Ltd |
Therapeutic molecules that bind to LAG3
|
WO2019162325A1
(en)
|
2018-02-21 |
2019-08-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sk1 as biomarker for predicting response to immunecheckpoint inhibitors
|
JP7474709B2
(ja)
|
2018-02-27 |
2024-04-25 |
インサイト・コーポレイション |
A2a/a2b阻害剤としてのイミダゾピリミジン及びトリアゾロピリミジン
|
JP2021517127A
(ja)
*
|
2018-03-06 |
2021-07-15 |
アンスティテュ キュリィ |
癌併用療法における使用のためのsetdb1ヒストンメチルトランスフェラーゼの阻害剤
|
KR102043468B1
(ko)
*
|
2018-03-14 |
2019-11-11 |
경북대학교 산학협력단 |
엡스타인 바 바이러스 연관 위암의 재발 가능성 예측을 위한 정보제공 방법
|
RU2020133020A
(ru)
|
2018-03-14 |
2022-04-14 |
Мерк Патент Гмбх |
Соединения и их применения для лечения опухолей у субъекта
|
CA3092695A1
(en)
|
2018-03-23 |
2019-09-26 |
Board Of Regents, The University Of Texas System |
Human pd-l2 antibodies and methods of use therefor
|
CN108530537B
(zh)
*
|
2018-03-29 |
2019-07-02 |
中国人民解放军军事科学院军事医学研究院 |
Pd-1/pd-l1信号通路抑制剂
|
WO2019185792A1
(en)
|
2018-03-29 |
2019-10-03 |
Philogen S.P.A |
Cancer treatment using immunoconjugates and immune check-point inhibitors
|
MX2020010407A
(es)
|
2018-04-03 |
2020-10-22 |
Merck Sharp & Dohme |
Benzotiofenos y compuestos relacionados como agonistas de sting.
|
EP3774765A4
(en)
|
2018-04-03 |
2021-12-29 |
Merck Sharp & Dohme Corp. |
Aza-benzothiophene compounds as sting agonists
|
US11874276B2
(en)
|
2018-04-05 |
2024-01-16 |
Dana-Farber Cancer Institute, Inc. |
STING levels as a biomarker for cancer immunotherapy
|
WO2019193540A1
(en)
|
2018-04-06 |
2019-10-10 |
Glaxosmithkline Intellectual Property Development Limited |
Heteroaryl derivatives of formula (i) as atf4 inhibitors
|
WO2019193541A1
(en)
|
2018-04-06 |
2019-10-10 |
Glaxosmithkline Intellectual Property Development Limited |
Bicyclic aromatic ring derivatives of formula (i) as atf4 inhibitors
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
SG11202010153WA
(en)
|
2018-04-17 |
2020-11-27 |
Tempest Therapeutics Inc |
Bicyclic carboxamides and methods of use thereof
|
CA3097369A1
(en)
|
2018-04-17 |
2019-10-24 |
Celldex Therapeutics, Inc. |
Anti-cd27 and anti-pd-l1 antibodies and bispecific constructs
|
WO2019204179A1
(en)
|
2018-04-20 |
2019-10-24 |
Merck Sharp & Dohme Corp. |
Novel substituted rig-i agonists: compositions and methods thereof
|
CA3096909A1
(en)
|
2018-04-26 |
2019-10-31 |
Agenus Inc. |
Heat shock protein-binding peptide compositions and methods of use thereof
|
WO2019207030A1
(en)
|
2018-04-26 |
2019-10-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting a response with an immune checkpoint inhibitor in a patient suffering from a lung cancer
|
BR112020022373A2
(pt)
|
2018-05-04 |
2021-02-02 |
Incyte Corporation |
sais de um inibidor de fgfr
|
CN112512576A
(zh)
|
2018-05-04 |
2021-03-16 |
默克专利有限公司 |
PD-1/PD-L1、TGFβ和DNA-PK联合抑制用于治疗癌症
|
SG11202010636VA
(en)
|
2018-05-04 |
2020-11-27 |
Incyte Corp |
Solid forms of an fgfr inhibitor and processes for preparing the same
|
GB201807924D0
(en)
|
2018-05-16 |
2018-06-27 |
Ctxt Pty Ltd |
Compounds
|
CA3100731A1
(en)
|
2018-05-18 |
2019-11-21 |
Incyte Corporation |
Fused pyrimidine derivatives as a2a / a2b inhibitors
|
CA3101174A1
(en)
|
2018-05-23 |
2019-11-28 |
Celgene Corporation |
Treating multiple myeloma and the use of biomarkers for 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1- oxoisoindolin-4-yl)oxy)methyl)benzyl) piperazin-1-yl)-3-fluorobenzonitrile
|
HRP20230449T1
(hr)
|
2018-05-23 |
2023-07-21 |
Celgene Corporation |
Antiproliferativni spojevi i bispecifična protutijela protiv bcma i cd3 za kombiniranu upotrebu
|
TWI806870B
(zh)
*
|
2018-05-23 |
2023-07-01 |
中國大陸商大有華夏生物醫藥集團有限公司 |
抗pd-1抗體及其用途
|
TW202015726A
(zh)
|
2018-05-30 |
2020-05-01 |
瑞士商諾華公司 |
Entpd2抗體、組合療法、及使用該等抗體和組合療法之方法
|
US20210253614A1
(en)
|
2018-05-31 |
2021-08-19 |
Peloton Therapeutics, Inc. |
Compositions and methods for inhibiting cd73
|
US11352320B2
(en)
|
2018-05-31 |
2022-06-07 |
Merck Sharp & Dohme Corp. |
Substituted [1.1.1] bicyclo compounds as indoleamine 2,3-dioxygenase inhibitors
|
WO2019232244A2
(en)
|
2018-05-31 |
2019-12-05 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
CU20200089A7
(es)
|
2018-06-01 |
2021-07-02 |
Novartis Ag |
Moléculas de unión contra bcma
|
EP3806848A2
(en)
|
2018-06-15 |
2021-04-21 |
Flagship Pioneering Innovations V, Inc. |
Increasing immune activity through modulation of postcellular signaling factors
|
CN113166153A
(zh)
|
2018-07-05 |
2021-07-23 |
因赛特公司 |
作为a2a/a2b抑制剂的稠合吡嗪衍生物
|
CA3105942A1
(en)
|
2018-07-09 |
2020-01-16 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds
|
HRP20231295T1
(hr)
|
2018-07-10 |
2024-02-02 |
Novartis Ag |
Derivati 3-(5-hidroksi-1-oksoizoindolin-2-il)piperidin-2,6-diona i njihova upotreba u liječenju bolesti ovisnih o cinkovom prstu 2 (ikzf2) obitelji ikaros
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
MA53381A
(fr)
|
2018-07-24 |
2021-06-02 |
Amgen Inc |
Association d'inhibiteurs de la voie lilrb1/2 et d'inhibiteurs de la voie pd-1
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
CN112703011A
(zh)
|
2018-08-06 |
2021-04-23 |
国家医疗保健研究所 |
用于治疗癌症的方法和组合物
|
WO2020030571A1
(en)
|
2018-08-06 |
2020-02-13 |
Glaxosmithkline Intellectual Property Development Limited |
Combinations of a pd-1 antibody and a tlr4 modulator and uses thereof
|
WO2020031107A1
(en)
|
2018-08-08 |
2020-02-13 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds
|
WO2020033791A1
(en)
|
2018-08-09 |
2020-02-13 |
Verseau Therapeutics, Inc. |
Oligonucleotide compositions for targeting ccr2 and csf1r and uses thereof
|
JP7488534B2
(ja)
*
|
2018-08-20 |
2024-05-22 |
1グローブ バイオメディカル カンパニー, リミテッド |
新規ながん免疫療法抗体組成物
|
WO2020044206A1
(en)
|
2018-08-29 |
2020-03-05 |
Glaxosmithkline Intellectual Property Development Limited |
Heterocyclic amides as kinase inhibitors for use in the treatment cancer
|
WO2020044252A1
(en)
|
2018-08-31 |
2020-03-05 |
Novartis Ag |
Dosage regimes for anti-m-csf antibodies and uses thereof
|
WO2020049534A1
(en)
|
2018-09-07 |
2020-03-12 |
Novartis Ag |
Sting agonist and combination therapy thereof for the treatment of cancer
|
AU2019346012A1
(en)
|
2018-09-26 |
2021-04-15 |
Merck Patent Gmbh |
Combination of a PD-1 antagonist, an ATR inhibitor and a platinating agent for the treatment of cancer
|
US11066404B2
(en)
|
2018-10-11 |
2021-07-20 |
Incyte Corporation |
Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors
|
WO2020081493A1
(en)
|
2018-10-16 |
2020-04-23 |
Molecular Templates, Inc. |
Pd-l1 binding proteins
|
CN112867803A
(zh)
|
2018-10-16 |
2021-05-28 |
诺华股份有限公司 |
单独的或与免疫标志物组合的肿瘤突变负荷作为生物标志物用于预测对靶向疗法的应答
|
CA3115802A1
(en)
|
2018-10-17 |
2020-04-23 |
Biolinerx Ltd. |
Treatment of metastatic pancreatic adenocarcinoma
|
JP2022505113A
(ja)
|
2018-10-18 |
2022-01-14 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
固形腫瘍の処置のためのβig-h3アンタゴニストと免疫チェックポイント阻害剤との組み合わせ
|
JP2022513374A
(ja)
|
2018-10-22 |
2022-02-07 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド |
投薬
|
CN111088231A
(zh)
*
|
2018-10-24 |
2020-05-01 |
艾生命序公司 |
Pd-l1抗体分泌的抗间皮素car-t细胞肿瘤免疫治疗
|
JP2022513400A
(ja)
|
2018-10-29 |
2022-02-07 |
メルサナ セラピューティクス インコーポレイテッド |
ペプチド含有リンカーを有するシステイン操作抗体-薬物コンジュゲート
|
EP3873532A1
(en)
|
2018-10-31 |
2021-09-08 |
Novartis AG |
Dc-sign antibody drug conjugates
|
US20210395240A1
(en)
|
2018-11-01 |
2021-12-23 |
Merck Sharp & Dohme Corp. |
Novel substituted pyrazole compounds as indoleamine 2,3-dioxygenase inhibitors
|
EP3877366A4
(en)
|
2018-11-06 |
2022-08-24 |
Merck Sharp & Dohme Corp. |
NOVEL SUBSTITUTED TRICYCLIC COMPOUNDS AS INDOLAMINE-2,3-DIOXYGENASE INHIBITORS
|
SG11202104300PA
(en)
|
2018-11-06 |
2021-05-28 |
Genmab As |
Antibody formulation
|
CA3119161A1
(en)
*
|
2018-11-13 |
2020-05-22 |
Compass Therapeutics Llc |
Multispecific binding constructs against checkpoint molecules and uses thereof
|
TW202028222A
(zh)
|
2018-11-14 |
2020-08-01 |
美商Ionis製藥公司 |
Foxp3表現之調節劑
|
FI3880186T3
(fi)
|
2018-11-14 |
2024-05-30 |
Regeneron Pharma |
PD-1-inhibiittoreiden intralesionaalinen antaminen ihosyövän hoitamiseksi
|
MX2021005651A
(es)
|
2018-11-16 |
2021-09-10 |
Arqule Inc |
Combinacion farmaceutica para el tratamiento contra el cancer.
|
US20230183379A1
(en)
|
2018-11-20 |
2023-06-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Bispecific antibody targeting transferrin receptor 1 and soluble antigen
|
WO2020106560A1
(en)
|
2018-11-20 |
2020-05-28 |
Merck Sharp & Dohme Corp. |
Substituted amino triazolopyrimidine and amino triazolopyrazine adenosine receptor antagonists, pharmaceutical compositions and their use
|
US20210395255A1
(en)
|
2018-11-20 |
2021-12-23 |
Merck Sharp & Dohme Corp. |
Substituted amino triazolopyrimidine and amino triazolopyrazine adenosine receptor antagonists, pharmaceutical compositions and their use
|
WO2020104479A1
(en)
|
2018-11-20 |
2020-05-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating cancers and resistant cancers with anti transferrin receptor 1 antibodies
|
CN113453678A
(zh)
|
2018-11-26 |
2021-09-28 |
德彪药业国际股份公司 |
Hiv感染的联合治疗
|
EP3886845A4
(en)
|
2018-11-28 |
2022-08-10 |
Merck Sharp & Dohme Corp. |
NEW SUBSTITUTED PIPERAZINE AMIDE COMPOUNDS USED AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS
|
EP3886988A1
(en)
|
2018-11-30 |
2021-10-06 |
Merck Sharp & Dohme Corp. |
9-substituted amino triazolo quinazoline derivatives as adenosine receptor antagonists, pharmaceutical compositions and their use
|
BR112021010353A2
(pt)
|
2018-11-30 |
2021-08-31 |
Glaxosmithkline Intellectual Property Development Limited |
Compostos úteis em terapia hiv
|
MX2021006544A
(es)
|
2018-12-04 |
2021-07-07 |
Sumitomo Pharma Oncology Inc |
Inhibidores de cinasa dependiente de ciclina 9 (cdk9) y polimorfos de los mismos para uso como agentes para el tratamiento de cancer.
|
WO2020115261A1
(en)
|
2018-12-07 |
2020-06-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
SG11202104331YA
(en)
|
2018-12-11 |
2021-05-28 |
Theravance Biopharma R&D Ip Llc |
Naphthyridine and quinoline derivatives useful as alk5 inhibitors
|
WO2020120592A1
(en)
|
2018-12-12 |
2020-06-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating melanoma
|
WO2020127411A1
(en)
|
2018-12-19 |
2020-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating cancers by immuno-modulation using antibodies against cathespin-d
|
MX2021007392A
(es)
|
2018-12-20 |
2021-08-24 |
Novartis Ag |
Regimen de dosificacion y combinacion farmaceutica que comprende derivados de 3-(1-oxoisoindolin-2-il)piperidina-2,6-diona.
|
WO2020128613A1
(en)
|
2018-12-21 |
2020-06-25 |
Novartis Ag |
Use of il-1beta binding antibodies
|
JP2022514087A
(ja)
|
2018-12-21 |
2022-02-09 |
ノバルティス アーゲー |
IL-1β結合抗体の使用
|
KR20210107730A
(ko)
|
2018-12-21 |
2021-09-01 |
노파르티스 아게 |
골수 형성이상 증후군의 치료 또는 예방에서의 il-1 베타 항체의 용도
|
WO2020127885A1
(en)
|
2018-12-21 |
2020-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Compositions for treating cancers and resistant cancers
|
US20220054524A1
(en)
|
2018-12-21 |
2022-02-24 |
Onxeo |
New conjugated nucleic acid molecules and their uses
|
WO2020128893A1
(en)
|
2018-12-21 |
2020-06-25 |
Pfizer Inc. |
Combination treatments of cancer comprising a tlr agonist
|
WO2020128637A1
(en)
|
2018-12-21 |
2020-06-25 |
Novartis Ag |
Use of il-1 binding antibodies in the treatment of a msi-h cancer
|
WO2020140012A1
(en)
|
2018-12-27 |
2020-07-02 |
Amgen Inc. |
Lyophilized virus formulations
|
WO2020141199A1
(en)
|
2019-01-03 |
2020-07-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for enhancing cd8+ t cell-dependent immune responses in subjects suffering from cancer
|
CA3125756A1
(en)
|
2019-01-09 |
2020-07-16 |
Celgene Corporation |
Solid forms comprising (s)-4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl) benzyl)piperazin-1-yl)-3-fluorobenzonitrile and salts thereof, and compositions comprising and methods of using the same
|
WO2020146441A1
(en)
|
2019-01-09 |
2020-07-16 |
Celgene Corporation |
Pharmaceutical compositions comprising (s)-4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl) benzyl)piperazin-1-yl)-3-fluorobenzonitrile and methods of using the same
|
KR20210126011A
(ko)
|
2019-01-09 |
2021-10-19 |
셀진 코포레이션 |
다발성 골수종 치료에 사용하기 위한 항증식성 화합물 및 2차 활성제
|
TWI829857B
(zh)
|
2019-01-29 |
2024-01-21 |
美商英塞特公司 |
作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶
|
US20220107323A1
(en)
|
2019-01-30 |
2022-04-07 |
Inserm(Institut National De La Santé Et De La Recherche Médicale) |
Methods and compositions for identifying whether a subject suffering from a cancer will achieve a response with an immune-checkpoint inhibitor
|
EP3922647A4
(en)
|
2019-02-03 |
2023-05-24 |
Jiangsu Hengrui Medicine Co., Ltd. |
ANTI-PD-1 ANTIBODY, ANTIGEN-BINDING FRAGMENT THEREOF AND PHARMACEUTICAL USE THEREOF
|
EP3921031A1
(en)
|
2019-02-04 |
2021-12-15 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and compositions for modulating blood-brain barrier
|
KR20210146290A
(ko)
|
2019-02-12 |
2021-12-03 |
스미토모 다이니폰 파마 온콜로지, 인크. |
헤테로시클릭 단백질 키나제 억제제를 포함하는 제제
|
TW202045172A
(zh)
|
2019-02-12 |
2020-12-16 |
瑞士商諾華公司 |
包含tno155和pd-1抑制劑之藥物組合
|
US20220098674A1
(en)
|
2019-02-13 |
2022-03-31 |
Inserm (Institut National De La Santé Et Dr La Recherch Médicale) |
Methods and compositions for selecting a cancer treatment in a subject suffering from cancer
|
JP7483732B2
(ja)
|
2019-02-15 |
2024-05-15 |
ノバルティス アーゲー |
3-(1-オキソ-5-(ピペリジン-4-イル)イソインドリン-2-イル)ピペリジン-2,6-ジオン誘導体及びその使用
|
US20220107320A1
(en)
|
2019-02-15 |
2022-04-07 |
Incelldx, Inc. |
Assaying Bladder-Associated Samples, Identifying and Treating Bladder-Associated Neoplasia, and Kits for Use Therein
|
WO2020165834A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
WO2020168197A1
(en)
|
2019-02-15 |
2020-08-20 |
Incyte Corporation |
Pyrrolo[2,3-d]pyrimidinone compounds as cdk2 inhibitors
|
WO2020168178A1
(en)
|
2019-02-15 |
2020-08-20 |
Incyte Corporation |
Cyclin-dependent kinase 2 biomarkers and uses thereof
|
CN109777824A
(zh)
*
|
2019-02-21 |
2019-05-21 |
王跃驹 |
植物作为宿主在表达hiv中和抗体中的应用
|
KR20210134690A
(ko)
|
2019-02-28 |
2021-11-10 |
리제너론 파아마슈티컬스, 인크. |
피부 암을 치료하기 위한 pd-1 억제제의 투여
|
AU2020232264A1
(en)
|
2019-03-05 |
2021-08-26 |
Amgen Inc. |
Use of oncolytic viruses for the treatment of cancer
|
TW202100520A
(zh)
|
2019-03-05 |
2021-01-01 |
美商英塞特公司 |
作為cdk2 抑制劑之吡唑基嘧啶基胺化合物
|
CN113677707A
(zh)
|
2019-03-06 |
2021-11-19 |
瑞泽恩制药公司 |
用于在治疗癌症中增强效力的il-4/il-13途径抑制剂
|
WO2020185532A1
(en)
|
2019-03-08 |
2020-09-17 |
Incyte Corporation |
Methods of treating cancer with an fgfr inhibitor
|
BR112021017864A2
(pt)
*
|
2019-03-12 |
2021-12-07 |
Harvard College |
Métodos e composições para tratamento do câncer
|
WO2020191326A1
(en)
|
2019-03-20 |
2020-09-24 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Treatment of acute myeloid leukemia (aml) with venetoclax failure
|
KR20210141621A
(ko)
|
2019-03-22 |
2021-11-23 |
스미토모 다이니폰 파마 온콜로지, 인크. |
Pkm2 조정제를 포함하는 조성물 및 그를 사용한 치료 방법
|
WO2020205560A1
(en)
|
2019-03-29 |
2020-10-08 |
Incyte Corporation |
Sulfonylamide compounds as cdk2 inhibitors
|
TW202102543A
(zh)
|
2019-03-29 |
2021-01-16 |
美商安進公司 |
溶瘤病毒在癌症新輔助療法中之用途
|
EP3946324A4
(en)
|
2019-04-04 |
2022-11-30 |
Merck Sharp & Dohme LLC |
HISTONE DEACETYLASE-3 INHIBITORS USEFUL FOR THE TREATMENT OF CANCER, INFLAMMATION, NEURODEGENERATIVE DISEASES AND DIABETES
|
CN111826395A
(zh)
*
|
2019-04-18 |
2020-10-27 |
艾生命序公司 |
重组溶瘤病毒表达抗免疫检查点融合抗体及免疫刺激分子
|
EP3725370A1
(en)
|
2019-04-19 |
2020-10-21 |
ImmunoBrain Checkpoint, Inc. |
Modified anti-pd-l1 antibodies and methods and uses for treating a neurodegenerative disease
|
US20220220565A1
(en)
|
2019-04-30 |
2022-07-14 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
WO2020223469A1
(en)
|
2019-05-01 |
2020-11-05 |
Incyte Corporation |
N-(1-(methylsulfonyl)piperidin-4-yl)-4,5-di hydro-1h-imidazo[4,5-h]quinazolin-8-amine derivatives and related compounds as cyclin-dependent kinase 2 (cdk2) inhibitors for treating cancer
|
US11447494B2
(en)
|
2019-05-01 |
2022-09-20 |
Incyte Corporation |
Tricyclic amine compounds as CDK2 inhibitors
|
EP3962493A2
(en)
|
2019-05-03 |
2022-03-09 |
Flagship Pioneering Innovations V, Inc. |
Methods of modulating immune activity/level of irf or sting or of treating cancer, comprising the administration of a sting modulator and/or purinergic receptor modulator or postcellular signaling factor
|
KR20220012261A
(ko)
|
2019-05-07 |
2022-02-03 |
이뮤니컴 인코포레이티드 |
체외 성분채집술에 의한 체크포인트 억제제에 대한 반응 증가
|
CN110577599A
(zh)
*
|
2019-05-13 |
2019-12-17 |
深圳市润科生物科技有限公司 |
人源抗程序性死亡-1(pd-1)抗体及其应用
|
JP2022533390A
(ja)
|
2019-05-16 |
2022-07-22 |
スティングセラ インコーポレイテッド |
オキソアクリジニル酢酸誘導体および使用方法
|
JP2022533194A
(ja)
|
2019-05-16 |
2022-07-21 |
スティングセラ インコーポレイテッド |
ベンゾ[b][1,8]ナフチリジン酢酸誘導体および使用方法
|
AU2020278465A1
(en)
|
2019-05-20 |
2021-12-09 |
Dana-Farber Cancer Institute, Inc. |
Boronic ester prodrugs and uses thereof
|
AU2020281535A1
(en)
|
2019-05-24 |
2022-01-27 |
Merck Patent Gmbh |
Combination therapies using CDK inhibitors
|
US20210038684A1
(en)
|
2019-06-11 |
2021-02-11 |
Alkermes Pharma Ireland Limited |
Compositions and Methods for Cancer Immunotherapy
|
WO2020248156A1
(zh)
*
|
2019-06-12 |
2020-12-17 |
苏州工业园区唯可达生物科技有限公司 |
Pd-l1靶向结合剂及其用途
|
US20220233685A1
(en)
|
2019-06-18 |
2022-07-28 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and anti-pd-1 antibody
|
CN114630675A
(zh)
|
2019-06-18 |
2022-06-14 |
爱尔兰詹森科学公司 |
乙型肝炎病毒(hbv)疫苗和抗pd-1或抗pd-l1抗体的组合
|
EP3990635A1
(en)
|
2019-06-27 |
2022-05-04 |
Rigontec GmbH |
Design method for optimized rig-i ligands
|
WO2021003432A1
(en)
|
2019-07-02 |
2021-01-07 |
Fred Hutchinson Cancer Research Center |
Recombinant ad35 vectors and related gene therapy improvements
|
CA3145864A1
(en)
|
2019-07-03 |
2021-01-07 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Tyrosine kinase non-receptor 1 (tnk1) inhibitors and uses thereof
|
EP3998081A4
(en)
|
2019-07-05 |
2023-07-12 |
Ono Pharmaceutical Co., Ltd. |
TREATMENT OF BLOOD CANCER WITH PD-1/CD3 DUAL SPECIFICITY PROTEIN
|
WO2021007269A1
(en)
|
2019-07-09 |
2021-01-14 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
GB201910305D0
(en)
|
2019-07-18 |
2019-09-04 |
Ctxt Pty Ltd |
Compounds
|
GB201910304D0
(en)
|
2019-07-18 |
2019-09-04 |
Ctxt Pty Ltd |
Compounds
|
US12036204B2
(en)
|
2019-07-26 |
2024-07-16 |
Eisai R&D Management Co., Ltd. |
Pharmaceutical composition for treating tumor
|
US11083705B2
(en)
|
2019-07-26 |
2021-08-10 |
Eisai R&D Management Co., Ltd. |
Pharmaceutical composition for treating tumor
|
TW202120500A
(zh)
|
2019-08-02 |
2021-06-01 |
美商梅爾莎納醫療公司 |
干擾素基因刺激蛋白(sting)激動劑化合物及用途
|
WO2021024020A1
(en)
|
2019-08-06 |
2021-02-11 |
Astellas Pharma Inc. |
Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
|
US20220332825A1
(en)
|
2019-08-08 |
2022-10-20 |
Ono Pharmaceutical Co., Ltd. |
Bispecific protein
|
US11427567B2
(en)
|
2019-08-14 |
2022-08-30 |
Incyte Corporation |
Imidazolyl pyrimidinylamine compounds as CDK2 inhibitors
|
WO2021041532A1
(en)
|
2019-08-26 |
2021-03-04 |
Dana-Farber Cancer Institute, Inc. |
Use of heparin to promote type 1 interferon signaling
|
CN110687281B
(zh)
*
|
2019-08-26 |
2023-05-23 |
中国医学科学院肿瘤医院 |
Pd-l1自身抗体在肿瘤预后评估中的应用
|
MX2022002315A
(es)
|
2019-08-30 |
2022-03-25 |
Agenus Inc |
Anticuerpos anti-cd96 y sus metodos de uso.
|
WO2021048292A1
(en)
|
2019-09-11 |
2021-03-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
AU2020351178A1
(en)
|
2019-09-17 |
2022-03-17 |
Bial-R&D Investments, S.A. |
Substituted, saturated and unsaturated N-heterocyclic carboxamides and related compounds for their use in the treatment of medical disorders
|
CA3151022A1
(en)
|
2019-09-17 |
2021-03-25 |
Bial - R&D Investments, S.A. |
Substituted n-heterocyclic carboxamides as acid ceramidase inhibitors and their use as medicaments
|
EP4031531A1
(en)
|
2019-09-17 |
2022-07-27 |
Bial-R&D Investments, S.A. |
Substituted imidazole carboxamides and their use in the treatment of medical disorders
|
CN114502590A
(zh)
|
2019-09-18 |
2022-05-13 |
诺华股份有限公司 |
Entpd2抗体、组合疗法、以及使用这些抗体和组合疗法的方法
|
CA3149621A1
(en)
|
2019-09-18 |
2021-03-25 |
Molecular Templates, Inc. |
Pd-l1 binding molecules comprising shiga toxin a subunit scaffolds
|
US11918649B2
(en)
|
2019-09-18 |
2024-03-05 |
Molecular Templates, Inc. |
PD-L1-binding molecules comprising Shiga toxin a subunit scaffolds
|
TW202124446A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
與entpd2抗體之組合療法
|
JP2022552090A
(ja)
|
2019-09-20 |
2022-12-15 |
トランスジーン |
Hpvポリペプチドおよびil-2をコードするポックスウイルスと抗pd-l1抗体の組合せ
|
EP4034562A2
(en)
|
2019-09-27 |
2022-08-03 |
GlaxoSmithKline Intellectual Property Development Limited |
Antigen binding proteins
|
WO2021064180A1
(en)
|
2019-10-03 |
2021-04-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for modulating macrophages polarization
|
CN115298177A
(zh)
|
2019-10-11 |
2022-11-04 |
因赛特公司 |
作为cdk2抑制剂的双环胺
|
US11781138B2
(en)
|
2019-10-14 |
2023-10-10 |
Aro Biotherapeutics Company |
FN3 domain-siRNA conjugates and uses thereof
|
BR112022007163A2
(pt)
|
2019-10-14 |
2022-08-23 |
Incyte Corp |
Heterociclos bicíclicos como inibidores de fgfr
|
CN114786682B
(zh)
|
2019-10-14 |
2024-07-16 |
Aro生物疗法公司 |
结合cd71的纤维粘连蛋白iii型结构域
|
US11566028B2
(en)
|
2019-10-16 |
2023-01-31 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
WO2021074391A1
(en)
|
2019-10-17 |
2021-04-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for diagnosing nasal intestinal type adenocarcinomas
|
WO2021079188A1
(en)
|
2019-10-21 |
2021-04-29 |
Novartis Ag |
Combination therapies with venetoclax and tim-3 inhibitors
|
BR112022007179A2
(pt)
|
2019-10-21 |
2022-08-23 |
Novartis Ag |
Inibidores de tim-3 e usos dos mesmos
|
EP4051286A1
(en)
|
2019-10-29 |
2022-09-07 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and compositions for treating uveal melanoma
|
KR20220092540A
(ko)
|
2019-10-29 |
2022-07-01 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
암을 치료하기 위한 pd-1 길항제, vegfr/fgfr/ret 티로신 키나제 억제제 및 cbp/베타-카테닌 억제제의 조합물
|
WO2021090146A1
(en)
|
2019-11-04 |
2021-05-14 |
Astrazeneca Ab |
Combination therapy for treating cancer
|
BR112022009031A2
(pt)
|
2019-11-11 |
2022-10-11 |
Incyte Corp |
Sais e formas cristalinas de um inibidor de pd-1/pd-l1
|
WO2021102343A1
(en)
|
2019-11-22 |
2021-05-27 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Solid dose pharmaceutical composition
|
US11590116B2
(en)
|
2019-11-22 |
2023-02-28 |
Theravance Biopharma R&D Ip, Llc |
Substituted pyridines and methods of use
|
PE20221504A1
(es)
|
2019-12-04 |
2022-09-30 |
Incyte Corp |
Derivados de un inhibidor de fgfr
|
EP4069696A1
(en)
|
2019-12-04 |
2022-10-12 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
EP4070113A4
(en)
|
2019-12-04 |
2023-12-20 |
Biora Therapeutics, Inc. |
ASSESSMENT OF PREECAMPSIA USING FREE AND DISSOCIATE PLACENTAL GROWTH FACTOR ASSAYS
|
US20230074558A1
(en)
|
2019-12-06 |
2023-03-09 |
Mersana Therapeutics, Inc. |
Dimeric compounds as sting agonists
|
CN114728875A
(zh)
|
2019-12-13 |
2022-07-08 |
因思博纳公司 |
金属盐及其用途
|
EP4076434A1
(en)
|
2019-12-17 |
2022-10-26 |
Flagship Pioneering Innovations V, Inc. |
Combination anti-cancer therapies with inducers of iron-dependent cellular disassembly
|
WO2021123243A1
(en)
|
2019-12-19 |
2021-06-24 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and vaccine compositions to treat cancers
|
US20230057071A1
(en)
|
2019-12-20 |
2023-02-23 |
Novartis Ag |
Combination of anti tim-3 antibody mbg453 and anti tgf-beta antibody nis793, with or without decitabine or the anti pd-1 antibody spartalizumab, for treating myelofibrosis and myelodysplastic syndrome
|
WO2021138512A1
(en)
|
2020-01-03 |
2021-07-08 |
Incyte Corporation |
Combination therapy comprising a2a/a2b and pd-1/pd-l1 inhibitors
|
US11981705B2
(en)
|
2020-01-10 |
2024-05-14 |
The Brigham And Women's Hospital, Inc. |
Methods and compositions for delivery of immunotherapy agents across the blood-brain barrier to treat brain cancer
|
WO2021146424A1
(en)
|
2020-01-15 |
2021-07-22 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
US20230076415A1
(en)
|
2020-01-17 |
2023-03-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
US20230058489A1
(en)
|
2020-01-17 |
2023-02-23 |
Novartis Ag |
Combination comprising a tim-3 inhibitor and a hypomethylating agent for use in treating myelodysplastic syndrome or chronic myelomonocytic leukemia
|
CA3161513A1
(en)
|
2020-01-28 |
2021-08-05 |
Irwin DAVIDSON |
Antisense oligonucleotide targeting linc00518 for treating melanoma
|
WO2021156360A1
(en)
|
2020-02-05 |
2021-08-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for discontinuing a treatment with a tyrosine kinase inhibitor (tki)
|
US20210244743A1
(en)
*
|
2020-02-07 |
2021-08-12 |
Al Therapeutics, Inc. |
Anti-viral compositions and methods of use
|
EP4110955A1
(en)
|
2020-02-28 |
2023-01-04 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for diagnosing, prognosing and managing treatment of breast cancer
|
IL295626A
(en)
|
2020-02-28 |
2022-10-01 |
Novartis Ag |
A triple drug combination that includes dabrafenib, an erk inhibitor and a raf inhibitor
|
MX2022010936A
(es)
|
2020-03-05 |
2022-11-16 |
Neotx Therapeutics Ltd |
³métodos y composiciones para el tratamiento del cáncer con células inmunológicas.
|
AU2021230385A1
(en)
|
2020-03-06 |
2022-09-22 |
Incyte Corporation |
Combination therapy comprising AXL/MER and PD-1/PD-L1 inhibitors
|
WO2021183318A2
(en)
|
2020-03-09 |
2021-09-16 |
President And Fellows Of Harvard College |
Methods and compositions relating to improved combination therapies
|
US11673879B2
(en)
|
2020-03-31 |
2023-06-13 |
Theravance Biopharma R&D Ip, Llc |
Substituted pyrimidines and methods of use
|
US20230149543A1
(en)
|
2020-04-14 |
2023-05-18 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatment for cancer based upon an icos antbody and a pd-l1 antibody tgf-bets-receptor fusion protein
|
CN115698075A
(zh)
|
2020-04-14 |
2023-02-03 |
葛兰素史密斯克莱知识产权发展有限公司 |
涉及抗icos和抗pd1抗体,任选地进一步涉及抗tim3抗体的癌症的组合治疗
|
US20230131598A1
(en)
|
2020-04-14 |
2023-04-27 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatment for cancer
|
WO2021211864A1
(en)
|
2020-04-16 |
2021-10-21 |
Incyte Corporation |
Fused tricyclic kras inhibitors
|
EP4138819A1
(en)
|
2020-04-21 |
2023-03-01 |
Novartis AG |
Dosing regimen for treating a disease modulated by csf-1r
|
TW202206100A
(zh)
|
2020-04-27 |
2022-02-16 |
美商西健公司 |
癌症之治療
|
CN115835909A
(zh)
|
2020-05-05 |
2023-03-21 |
泰昂治疗公司 |
大麻素受体2型(cb2)调节剂和其用途
|
WO2021226063A1
(en)
|
2020-05-05 |
2021-11-11 |
Regeneron Pharmaceuticals, Inc. |
Car comprising cd28 zeta and cd3 zeta
|
EP4146644A1
(en)
|
2020-05-06 |
2023-03-15 |
Merck Sharp & Dohme LLC |
Il4i1 inhibitors and methods of use
|
WO2021231526A1
(en)
|
2020-05-13 |
2021-11-18 |
Incyte Corporation |
Fused pyrimidine compounds as kras inhibitors
|
TW202210098A
(zh)
|
2020-05-26 |
2022-03-16 |
美商再生元醫藥公司 |
通過投予pd-1抑制劑治療子宮頸癌的方法
|
WO2021242794A2
(en)
|
2020-05-29 |
2021-12-02 |
President And Fellows Of Harvard College |
Living cells engineered with polyphenol-functionalized biologically active nanocomplexes
|
CN116323607A
(zh)
|
2020-06-10 |
2023-06-23 |
施万生物制药研发Ip有限责任公司 |
用作alk5抑制剂的萘啶衍生物
|
WO2021249969A1
(en)
|
2020-06-10 |
2021-12-16 |
Merck Patent Gmbh |
Combination product for the treatment of cancer diseases
|
TW202214857A
(zh)
|
2020-06-19 |
2022-04-16 |
法商昂席歐公司 |
新型結合核酸分子及其用途
|
AU2021297099A1
(en)
|
2020-06-23 |
2023-01-05 |
Novartis Ag |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
US20230235077A1
(en)
|
2020-06-24 |
2023-07-27 |
The General Hospital Corporation |
Materials and methods of treating cancer
|
US20230293530A1
(en)
|
2020-06-24 |
2023-09-21 |
Yeda Research And Development Co. Ltd. |
Agents for sensitizing solid tumors to treatment
|
AU2021296876A1
(en)
|
2020-06-25 |
2023-02-02 |
Celgene Corporation |
Methods for treating cancer with combination therapies
|
US20230265145A1
(en)
|
2020-06-26 |
2023-08-24 |
Amgen Inc. |
Il-10 muteins and fusion proteins thereof
|
CN116096906A
(zh)
|
2020-06-29 |
2023-05-09 |
旗舰创业创新五公司 |
工程化以促进萨诺传递的病毒及其在治疗癌症中的用途
|
US20230266322A1
(en)
|
2020-06-30 |
2023-08-24 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the risk of recurrence and/or death of patients suffering from a solid cancer after preoperative adjuvant therapy and radical surgery
|
WO2022002873A1
(en)
|
2020-06-30 |
2022-01-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the risk of recurrence and/or death of patients suffering from a solid cancer after preoperative adjuvant therapies
|
US20230250173A1
(en)
|
2020-07-01 |
2023-08-10 |
Pfizer Inc. |
Biomarkers for pd-1 axis binding antagonist therapy
|
AU2021306613A1
(en)
|
2020-07-07 |
2023-02-02 |
BioNTech SE |
Therapeutic RNA for HPV-positive cancer
|
IL299657A
(en)
|
2020-07-07 |
2023-03-01 |
Celgene Corp |
Pharmaceutical preparations including (S)-4-(4-(4-(((2-(2,6-DIOXOPIPERIDIN-3-YL)-1-OXOISOINDOLIN-4-YL)OXY)M ETHYL) BENZYL)PIPERAZIN-1 -YL)-3-FLUOROBENZONITRILE AND METHODS OF USING THEM
|
WO2022009157A1
(en)
|
2020-07-10 |
2022-01-13 |
Novartis Ag |
Lhc165 and spartalizumab combinations for treating solid tumors
|
US20230266332A1
(en)
|
2020-07-28 |
2023-08-24 |
Inserm (Institut National De La Santè Et De La Recherch Médicale) |
Methods and compositions for preventing and treating a cancer
|
WO2022029573A1
(en)
|
2020-08-03 |
2022-02-10 |
Novartis Ag |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
US20230323470A1
(en)
|
2020-08-26 |
2023-10-12 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cancer by administering a pd-1 inhibitor
|
WO2022047093A1
(en)
|
2020-08-28 |
2022-03-03 |
Incyte Corporation |
Vinyl imidazole compounds as inhibitors of kras
|
US20230321285A1
(en)
|
2020-08-31 |
2023-10-12 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
US20230338587A1
(en)
|
2020-08-31 |
2023-10-26 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
CN111808196B
(zh)
*
|
2020-08-31 |
2020-12-29 |
北京百奥赛图基因生物技术有限公司 |
抗pd-1抗体及其用途
|
WO2022049526A1
(en)
|
2020-09-02 |
2022-03-10 |
Pharmabcine Inc. |
Combination therapy of a pd-1 antagonist and an antagonist for vegfr-2 for treating patients with cancer
|
CN116194142A
(zh)
|
2020-09-03 |
2023-05-30 |
瑞泽恩制药公司 |
通过施用pd-1抑制剂治疗癌症疼痛的方法
|
CA3195231A1
(en)
|
2020-09-16 |
2022-03-24 |
President And Fellows Of Harvard College |
Methods of treating an individual that has failed an anti-pd-1/anti-pd-l1 therapy
|
CN111956799A
(zh)
*
|
2020-09-18 |
2020-11-20 |
生物抗素公司 |
抗pd-1抗体和/或pd-l1抗体在制备治疗帕金森病药物中的应用
|
WO2022072783A1
(en)
|
2020-10-02 |
2022-04-07 |
Incyte Corporation |
Bicyclic dione compounds as inhibitors of kras
|
WO2022084531A1
(en)
|
2020-10-23 |
2022-04-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating glioma
|
TW202233185A
(zh)
|
2020-10-28 |
2022-09-01 |
日商衛材R&D企管股份有限公司 |
腫瘤治療用醫藥組合物
|
AU2021373366A1
(en)
|
2020-11-06 |
2023-06-01 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
WO2022099071A1
(en)
|
2020-11-06 |
2022-05-12 |
Incyte Corporation |
Process for making a pd-1/pd-l1 inhibitor and salts and crystalline forms thereof
|
US11760756B2
(en)
|
2020-11-06 |
2023-09-19 |
Incyte Corporation |
Crystalline form of a PD-1/PD-L1 inhibitor
|
US11780836B2
(en)
|
2020-11-06 |
2023-10-10 |
Incyte Corporation |
Process of preparing a PD-1/PD-L1 inhibitor
|
JP2023548538A
(ja)
|
2020-11-08 |
2023-11-17 |
シージェン インコーポレイテッド |
併用療法
|
WO2022101484A1
(en)
|
2020-11-16 |
2022-05-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating uveal melanoma
|
WO2022101481A1
(en)
|
2020-11-16 |
2022-05-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating uveal melanoma
|
US20220168293A1
(en)
|
2020-12-02 |
2022-06-02 |
Pfizer Inc. |
Time to resolution of axitinib-related adverse events
|
CA3201219A1
(en)
|
2020-12-04 |
2022-06-09 |
Mir Ali |
Ionizable cationic lipids and lipid nanoparticles, and methods of synthesis and use thereof
|
TW202237119A
(zh)
|
2020-12-10 |
2022-10-01 |
美商住友製藥腫瘤公司 |
Alk﹘5抑制劑和彼之用途
|
WO2022130206A1
(en)
|
2020-12-16 |
2022-06-23 |
Pfizer Inc. |
TGFβr1 INHIBITOR COMBINATION THERAPIES
|
EP4263600A1
(en)
|
2020-12-18 |
2023-10-25 |
Century Therapeutics, Inc. |
Chimeric antigen receptor systems with adaptable receptor specificity
|
WO2022135666A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Treatment schedule for cytokine proteins
|
WO2022135667A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Therapeutic rna for treating cancer
|
TW202245808A
(zh)
|
2020-12-21 |
2022-12-01 |
德商拜恩迪克公司 |
用於治療癌症之治療性rna
|
MX2023007850A
(es)
|
2020-12-29 |
2023-09-11 |
Incyte Corp |
Terapia combinada que comprende inhibidores de adora2a/adora2b (a2a/a2b), inhibidores de muerte programada/ligando 1 de muerte programada (pd-1/pd-l1) y anticuerpos de cumulo de diferenciacion 73 (anti-cd73).
|
EP4284919A1
(en)
|
2021-01-29 |
2023-12-06 |
Iovance Biotherapeutics, Inc. |
Methods of making modified tumor infiltrating lymphocytes and their use in adoptive cell therapy
|
US20240141060A1
(en)
|
2021-01-29 |
2024-05-02 |
Novartis Ag |
Dosage regimes for anti-cd73 and anti-entpd2 antibodies and uses thereof
|
CN114452403A
(zh)
|
2021-02-10 |
2022-05-10 |
同润生物医药(上海)有限公司 |
一种含有双功能免疫检查点/TGFβ抑制剂的药物组合
|
JP2024509529A
(ja)
|
2021-03-02 |
2024-03-04 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド |
Dnmt1阻害剤としての置換ピリジン
|
US20240165094A1
(en)
|
2021-03-17 |
2024-05-23 |
Institut National de la Santé et de la Recherche Médicale |
Methods and compositions for treating melanoma
|
JP2024511373A
(ja)
|
2021-03-18 |
2024-03-13 |
ノバルティス アーゲー |
がんのためのバイオマーカーおよびその使用
|
JP2024511067A
(ja)
|
2021-03-19 |
2024-03-12 |
トレインド セラピューティクス ディスカバリー,インコーポレーテッド |
訓練された免疫を調節するための化合物およびその使用方法
|
MX2023011007A
(es)
|
2021-03-23 |
2023-12-07 |
Regeneron Pharma |
Metodos para tratar el cancer en pacientes inmunosuprimidos o inmunocomprometidos mediante la administracion de un inhibidor de pd-1.
|
TW202304506A
(zh)
|
2021-03-25 |
2023-02-01 |
日商安斯泰來製藥公司 |
涉及抗claudin 18.2抗體的組合治療以治療癌症
|
WO2022208353A1
(en)
|
2021-03-31 |
2022-10-06 |
Glaxosmithkline Intellectual Property Development Limited |
Antigen binding proteins and combinations thereof
|
WO2022212784A1
(en)
|
2021-03-31 |
2022-10-06 |
Flagship Pioneering Innovations V, Inc. |
Thanotransmission polypeptides and their use in treating cancer
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
WO2022217123A2
(en)
|
2021-04-08 |
2022-10-13 |
Nurix Therapeutics, Inc. |
Combination therapies with cbl-b inhibitor compounds
|
AU2022253351A1
(en)
|
2021-04-09 |
2023-10-12 |
Ose Immunotherapeutics |
New scaffold for bifunctional molecules with improved properties
|
US20240182572A1
(en)
|
2021-04-09 |
2024-06-06 |
Ose Immunotherapeutics |
Scaffold for bifunctional molecules comprising pd-1 or cd28 and sirp binding domains
|
JP2024514816A
(ja)
|
2021-04-09 |
2024-04-03 |
シージェン インコーポレイテッド |
抗tigit抗体を用いるがんの治療方法
|
JP2024513575A
(ja)
|
2021-04-12 |
2024-03-26 |
インサイト・コーポレイション |
Fgfr阻害剤及びネクチン-4標的化剤を含む併用療法
|
BR112023021111A2
(pt)
|
2021-04-13 |
2023-12-19 |
Nuvalent Inc |
Composto, composição farmacêutica, método de tratamento de câncer, método para inibir seletivamente her2, método de regulação de um nível de her2, método para aumentar um nível de her2, método de diminuição da fosforilação de her2
|
AU2022258566A1
(en)
|
2021-04-14 |
2023-10-12 |
Aro Biotherapeutics Company |
Cd71 binding fibronectin type iii domains
|
BR112023020438A2
(pt)
|
2021-04-20 |
2024-03-12 |
Seagen Inc |
Modulação de citotoxicidade celular dependente de anticorpo
|
WO2022223791A1
(en)
|
2021-04-23 |
2022-10-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating cell senescence accumulation related disease
|
WO2022227015A1
(en)
|
2021-04-30 |
2022-11-03 |
Merck Sharp & Dohme Corp. |
Il4i1 inhibitors and methods of use
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
US20220396623A1
(en)
|
2021-05-18 |
2022-12-15 |
Kymab Limited |
Uses of anti-icos antibodies
|
WO2022251359A1
(en)
|
2021-05-26 |
2022-12-01 |
Theravance Biopharma R&D Ip, Llc |
Bicyclic inhibitors of alk5 and methods of use
|
EP4346904A1
(en)
|
2021-06-03 |
2024-04-10 |
Synthorx, Inc. |
Head and neck cancer combination therapy comprising an il-2 conjugate and cetuximab
|
GB202107994D0
(en)
|
2021-06-04 |
2021-07-21 |
Kymab Ltd |
Treatment of cancer
|
AU2022288058A1
(en)
|
2021-06-07 |
2023-11-16 |
Agonox, Inc. |
Cxcr5, pd-1, and icos expressing tumor reactive cd4 t cells and their use
|
JP2024522189A
(ja)
|
2021-06-09 |
2024-06-11 |
インサイト・コーポレイション |
Fgfr阻害剤としての三環式ヘテロ環
|
EP4352060A1
(en)
|
2021-06-09 |
2024-04-17 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
US11981671B2
(en)
|
2021-06-21 |
2024-05-14 |
Incyte Corporation |
Bicyclic pyrazolyl amines as CDK2 inhibitors
|
AU2022303363A1
(en)
|
2021-06-29 |
2024-01-18 |
Flagship Pioneering Innovations V, Inc. |
Immune cells engineered to promote thanotransmission and uses thereof
|
KR20240032915A
(ko)
|
2021-07-07 |
2024-03-12 |
인사이트 코포레이션 |
Kras의 저해제로서의 삼환식 화합물
|
KR20240046323A
(ko)
|
2021-07-13 |
2024-04-08 |
비온테크 에스이 |
암에 대한 병용 요법에 있어서 cd40 및 cd137에 대한 다중특이 결합제
|
JP2024529347A
(ja)
|
2021-07-14 |
2024-08-06 |
インサイト・コーポレイション |
Krasの阻害剤としての三環式化合物
|
IL310201A
(en)
|
2021-07-19 |
2024-03-01 |
Regeneron Pharma |
Combination of inhibitor-control inhibitor and oncolytic virus for cancer treatment
|
CN115521378B
(zh)
*
|
2021-07-23 |
2023-12-22 |
南京吉盛澳玛生物医药有限公司 |
Pd-l1抗体及其用途
|
WO2023010080A1
(en)
|
2021-07-30 |
2023-02-02 |
Seagen Inc. |
Treatment for cancer
|
CN117794953A
(zh)
|
2021-08-03 |
2024-03-29 |
豪夫迈·罗氏有限公司 |
双特异性抗体及使用方法
|
KR20240099138A
(ko)
|
2021-08-23 |
2024-06-28 |
이뮤니타스 테라퓨틱스, 인크. |
항-cd161 항체 및 그의 용도
|
EP4396187A1
(en)
|
2021-08-31 |
2024-07-10 |
Incyte Corporation |
Naphthyridine compounds as inhibitors of kras
|
TW202325306A
(zh)
|
2021-09-02 |
2023-07-01 |
美商天恩治療有限公司 |
改良免疫細胞之生長及功能的方法
|
WO2023049697A1
(en)
|
2021-09-21 |
2023-03-30 |
Incyte Corporation |
Hetero-tricyclic compounds as inhibitors of kras
|
WO2023051926A1
(en)
|
2021-09-30 |
2023-04-06 |
BioNTech SE |
Treatment involving non-immunogenic rna for antigen vaccination and pd-1 axis binding antagonists
|
EP4408536A1
(en)
|
2021-10-01 |
2024-08-07 |
Incyte Corporation |
Pyrazoloquinoline kras inhibitors
|
TW202327595A
(zh)
|
2021-10-05 |
2023-07-16 |
美商輝瑞大藥廠 |
用於治療癌症之氮雜內醯胺化合物的組合
|
CA3234647A1
(en)
|
2021-10-06 |
2023-04-13 |
Genmab A/S |
Multispecific binding agents against pd-l1 and cd137 in combination therapy
|
TW202333802A
(zh)
|
2021-10-11 |
2023-09-01 |
德商拜恩迪克公司 |
用於肺癌之治療性rna(二)
|
US11939328B2
(en)
|
2021-10-14 |
2024-03-26 |
Incyte Corporation |
Quinoline compounds as inhibitors of KRAS
|
WO2023081730A1
(en)
|
2021-11-03 |
2023-05-11 |
Teon Therapeutics, Inc. |
4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide derivatives as cannabinoid cb2 receptor modulators for the treatment of cancer
|
WO2023079428A1
(en)
|
2021-11-03 |
2023-05-11 |
Pfizer Inc. |
Combination therapies using tlr7/8 agonist
|
WO2023078900A1
(en)
|
2021-11-03 |
2023-05-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating triple negative breast cancer (tnbc)
|
WO2023083439A1
(en)
|
2021-11-09 |
2023-05-19 |
BioNTech SE |
Tlr7 agonist and combinations for cancer treatment
|
CA3240096A1
(en)
|
2021-11-12 |
2023-05-19 |
Novartis Ag |
Combination therapy for treating lung cancer
|
AU2022389961A1
(en)
|
2021-11-22 |
2024-06-06 |
Incyte Corporation |
Combination therapy comprising an fgfr inhibitor and a kras inhibitor
|
WO2023097211A1
(en)
|
2021-11-24 |
2023-06-01 |
The University Of Southern California |
Methods for enhancing immune checkpoint inhibitor therapy
|
WO2023102184A1
(en)
|
2021-12-03 |
2023-06-08 |
Incyte Corporation |
Bicyclic amine compounds as cdk12 inhibitors
|
US11976073B2
(en)
|
2021-12-10 |
2024-05-07 |
Incyte Corporation |
Bicyclic amines as CDK2 inhibitors
|
US20230183251A1
(en)
|
2021-12-10 |
2023-06-15 |
Incyte Corporation |
Bicyclic amines as cdk12 inhibitors
|
AU2022409713A1
(en)
|
2021-12-16 |
2024-06-20 |
Valerio Therapeutics |
New conjugated nucleic acid molecules and their uses
|
WO2023122573A1
(en)
|
2021-12-20 |
2023-06-29 |
Synthorx, Inc. |
Head and neck cancer combination therapy comprising an il-2 conjugate and pembrolizumab
|
WO2023118165A1
(en)
|
2021-12-21 |
2023-06-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
US20230192722A1
(en)
|
2021-12-22 |
2023-06-22 |
Incyte Corporation |
Salts and solid forms of an fgfr inhibitor and processes of preparing thereof
|
WO2023147488A1
(en)
|
2022-01-28 |
2023-08-03 |
Iovance Biotherapeutics, Inc. |
Cytokine associated tumor infiltrating lymphocytes compositions and methods
|
WO2023159102A1
(en)
|
2022-02-17 |
2023-08-24 |
Regeneron Pharmaceuticals, Inc. |
Combinations of checkpoint inhibitors and oncolytic virus for treating cancer
|
US20240117030A1
(en)
|
2022-03-03 |
2024-04-11 |
Pfizer Inc. |
Multispecific antibodies and uses thereof
|
WO2023172921A1
(en)
|
2022-03-07 |
2023-09-14 |
Incyte Corporation |
Solid forms, salts, and processes of preparation of a cdk2 inhibitor
|
WO2023174210A1
(en)
|
2022-03-14 |
2023-09-21 |
Laekna Limited |
Combination treatment for cancer
|
WO2023178192A1
(en)
|
2022-03-15 |
2023-09-21 |
Compugen Ltd. |
Il-18bp antagonist antibodies and their use in monotherapy and combination therapy in the treatment of cancer
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
WO2023215560A1
(en)
|
2022-05-05 |
2023-11-09 |
Atoosa Corporation |
Tumor cell/immune cell multivalent receptor engager – bio-nanoparticle (timre-bnp)
|
WO2023218046A1
(en)
|
2022-05-12 |
2023-11-16 |
Genmab A/S |
Binding agents capable of binding to cd27 in combination therapy
|
WO2023222854A1
(en)
|
2022-05-18 |
2023-11-23 |
Kymab Limited |
Uses of anti-icos antibodies
|
WO2023230554A1
(en)
|
2022-05-25 |
2023-11-30 |
Pfizer Inc. |
Combination of a braf inhibitor, an egfr inhibitor, and a pd-1 antagonist for the treatment of braf v600e-mutant, msi-h/dmmr colorectal cancer
|
WO2023230541A1
(en)
|
2022-05-27 |
2023-11-30 |
Viiv Healthcare Company |
Piperazine derivatives useful in hiv therapy
|
WO2023227949A1
(en)
|
2022-05-27 |
2023-11-30 |
Takeda Pharmaceutical Company Limited |
Dosing of cd38-binding fusion protein
|
WO2023240156A1
(en)
|
2022-06-08 |
2023-12-14 |
Tidal Therapeutics, Inc. |
Ionizable cationic lipids and lipid nanoparticles, and methods of synthesis and use thereof
|
WO2023239768A1
(en)
|
2022-06-08 |
2023-12-14 |
Incyte Corporation |
Tricyclic triazolo compounds as dgk inhibitors
|
TW202413359A
(zh)
|
2022-06-22 |
2024-04-01 |
美商英塞特公司 |
雙環胺cdk12抑制劑
|
US20240101557A1
(en)
|
2022-07-11 |
2024-03-28 |
Incyte Corporation |
Fused tricyclic compounds as inhibitors of kras g12v mutants
|
WO2024015803A2
(en)
|
2022-07-11 |
2024-01-18 |
Autonomous Therapeutics, Inc. |
Encrypted rna and methods of its use
|
WO2024015372A1
(en)
|
2022-07-14 |
2024-01-18 |
Teon Therapeutics, Inc. |
Adenosine receptor antagonists and uses thereof
|
WO2024033399A1
(en)
|
2022-08-10 |
2024-02-15 |
Institut National de la Santé et de la Recherche Médicale |
Sigmar1 ligand for the treatment of pancreatic cancer
|
WO2024033400A1
(en)
|
2022-08-10 |
2024-02-15 |
Institut National de la Santé et de la Recherche Médicale |
Sk2 inhibitor for the treatment of pancreatic cancer
|
WO2024056716A1
(en)
|
2022-09-14 |
2024-03-21 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical compositions for the treatment of dilated cardiomyopathy
|
WO2024077191A1
(en)
|
2022-10-05 |
2024-04-11 |
Flagship Pioneering Innovations V, Inc. |
Nucleic acid molecules encoding trif and additionalpolypeptides and their use in treating cancer
|
WO2024086827A2
(en)
|
2022-10-20 |
2024-04-25 |
Repertoire Immune Medicines, Inc. |
Cd8 t cell targeted il2
|
WO2024084013A1
(en)
|
2022-10-20 |
2024-04-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Combination therapy for the treatment of cancer
|
WO2024084034A1
(en)
|
2022-10-21 |
2024-04-25 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical compositions for the treatment of osteoarthritis
|
WO2024088967A1
(en)
*
|
2022-10-24 |
2024-05-02 |
Navigo Proteins Gmbh |
Novel proteins with high binding affinity to programmed death ligand 1 (pd-l1)
|
WO2024089418A1
(en)
|
2022-10-24 |
2024-05-02 |
Cancer Research Technology Limited |
Tumour sensitisation to checkpoint inhibitors with redox status modifier
|
WO2024089417A1
(en)
|
2022-10-24 |
2024-05-02 |
Memorial Sloan-Kettering Cancer Center |
Tumour stratification for responsiveness to an immune checkpoint inhibitor
|
WO2024108100A1
(en)
|
2022-11-18 |
2024-05-23 |
Incyte Corporation |
Heteroaryl fluoroalkenes as dgk inhibitors
|
WO2024115725A1
(en)
|
2022-12-01 |
2024-06-06 |
BioNTech SE |
Multispecific antibody against cd40 and cd137 in combination therapy with anti-pd1 ab and chemotherapy
|
WO2024126457A1
(en)
|
2022-12-14 |
2024-06-20 |
Astellas Pharma Europe Bv |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and immune checkpoint inhibitors
|
WO2024148243A1
(en)
|
2023-01-06 |
2024-07-11 |
Lassen Therapeutics 1, Inc. |
Anti-il-18bp antibodies
|
WO2024148241A1
(en)
|
2023-01-06 |
2024-07-11 |
Lassen Therapeutics 1, Inc. |
Anti-il-18bp antibodies
|
WO2024151687A1
(en)
|
2023-01-09 |
2024-07-18 |
Flagship Pioneering Innovations V, Inc. |
Genetic switches and their use in treating cancer
|
WO2024151346A1
(en)
|
2023-01-12 |
2024-07-18 |
Incyte Corporation |
Heteroaryl fluoroalkenes as dgk inhibitors
|
WO2024150017A1
(en)
|
2023-01-13 |
2024-07-18 |
Akrivia Biomedics Limited |
Method of profiling diseases
|
WO2024160721A1
(en)
|
2023-01-30 |
2024-08-08 |
Kymab Limited |
Antibodies
|
WO2024161015A1
(en)
|
2023-02-03 |
2024-08-08 |
Institut National de la Santé et de la Recherche Médicale |
Method to treat age-related diseases
|
WO2024161375A1
(en)
|
2023-02-04 |
2024-08-08 |
Mabtree Biologics Ag |
Human anti-pd-l2 antibody and its uses thereof
|