MA40948A - Formulation de virus de l'herpès simplex congelée stable - Google Patents

Formulation de virus de l'herpès simplex congelée stable

Info

Publication number
MA40948A
MA40948A MA040948A MA40948A MA40948A MA 40948 A MA40948 A MA 40948A MA 040948 A MA040948 A MA 040948A MA 40948 A MA40948 A MA 40948A MA 40948 A MA40948 A MA 40948A
Authority
MA
Morocco
Prior art keywords
herpes simplex
simplex virus
virus formulation
stable frozen
frozen
Prior art date
Application number
MA040948A
Other languages
English (en)
Inventor
Bruce Arthur Kerwin
Jennifer R Litowski
Christine Claudia Siska
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MA40948A publication Critical patent/MA40948A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/763—Herpes virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16621—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16632—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Composition de virus vivant qui maintient l'infectivité et améliore la stabilité du virus pendant un ou plusieurs cycles de congélation / décongélation et / ou au cours d'un stockage à long terme à l'état liquide à des températures comprises entre un point de congélation et la température ambiante.
MA040948A 2014-12-18 2015-12-15 Formulation de virus de l'herpès simplex congelée stable MA40948A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462093663P 2014-12-18 2014-12-18

Publications (1)

Publication Number Publication Date
MA40948A true MA40948A (fr) 2017-10-25

Family

ID=55229814

Family Applications (1)

Application Number Title Priority Date Filing Date
MA040948A MA40948A (fr) 2014-12-18 2015-12-15 Formulation de virus de l'herpès simplex congelée stable

Country Status (18)

Country Link
US (2) US20170360857A1 (fr)
EP (1) EP3234114B9 (fr)
JP (2) JP6975041B2 (fr)
KR (2) KR20230107375A (fr)
CN (1) CN107580626A (fr)
AU (3) AU2015362687B2 (fr)
BR (1) BR112017013009A2 (fr)
CA (1) CA2971201A1 (fr)
CL (1) CL2017001563A1 (fr)
CO (1) CO2017007086A2 (fr)
EA (1) EA201791382A1 (fr)
ES (1) ES2948037T3 (fr)
IL (3) IL308119B2 (fr)
MA (1) MA40948A (fr)
MX (2) MX2017008013A (fr)
SG (1) SG11201704975SA (fr)
WO (1) WO2016100364A1 (fr)
ZA (1) ZA201704695B (fr)

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WO2017013419A1 (fr) * 2015-07-20 2017-01-26 Virttu Biologics Limited Utilisation d'un virus herpes simplex oncolytique, seul ou en combinaison avec un inhibiteur de point de contrôle immunitaire, dans le traitement du cancer
WO2018201028A1 (fr) 2017-04-28 2018-11-01 Merck Sharp & Dohme Corp. Biomarqueurs pour thérapies anticancéreuses
WO2019213509A1 (fr) * 2018-05-03 2019-11-07 Rutgers, The State University Of New Jersey Compositions et méthodes pour le traitement du cancer
CN109161562A (zh) * 2018-08-09 2019-01-08 湖北科技学院 一种选择性杀灭肝癌细胞的新型溶瘤病毒及其构建方法
MX2021007639A (es) * 2018-12-27 2021-08-11 Amgen Inc Formulaciones de virus liofilizadas.
EP4179085A1 (fr) * 2020-07-07 2023-05-17 Oriengene Biotechnology Ltd Arn guide pour l'édition du gène hsv-1 et son procédé
CN115836123B (zh) * 2021-01-19 2024-12-31 新田明胶株式会社 病毒稳定剂、病毒稳定剂用明胶水解物以及含病毒的组合物
CN116421734A (zh) * 2021-12-30 2023-07-14 深圳复诺健生物科技有限公司 适用于溶瘤病毒的冻干保护剂及其应用
EP4442251A1 (fr) 2023-04-05 2024-10-09 Albumedix Ltd Formulations et leurs utilisations

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EP1141338A4 (fr) 1998-12-31 2002-09-25 Arch Dev Corp Virus de l'herpes simplex recombinant utile dans le traitement des maladies neoplasiques
WO2000054795A1 (fr) 1999-03-15 2000-09-21 The Trustees Of The University Of Pennsylvania Therapie combinee consistant a administrer un agent chimiotherapeutique et un virus oncolytique pour tuer des cellules cancereuses chez un sujet
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Also Published As

Publication number Publication date
MX2023012564A (es) 2023-11-08
EP3234114B9 (fr) 2023-06-14
KR20230107375A (ko) 2023-07-14
IL252942A0 (en) 2017-08-31
AU2015362687A1 (en) 2017-07-06
EP3234114A1 (fr) 2017-10-25
JP6975041B2 (ja) 2021-12-01
AU2022201523B2 (en) 2024-12-12
US20170360857A1 (en) 2017-12-21
CO2017007086A2 (es) 2017-10-10
CN107580626A (zh) 2018-01-12
WO2016100364A1 (fr) 2016-06-23
EA201791382A1 (ru) 2017-10-31
IL300202B1 (en) 2023-12-01
CL2017001563A1 (es) 2018-01-26
CA2971201A1 (fr) 2016-06-23
MX2017008013A (es) 2018-03-06
ZA201704695B (en) 2023-12-20
IL308119A (en) 2023-12-01
AU2015362687B2 (en) 2021-12-09
EP3234114B1 (fr) 2023-04-12
AU2022201523C1 (en) 2025-10-02
AU2022201523A1 (en) 2022-03-24
BR112017013009A2 (pt) 2018-06-26
IL308119B1 (en) 2025-07-01
US20210052680A1 (en) 2021-02-25
JP2021072795A (ja) 2021-05-13
AU2025201675A1 (en) 2025-03-27
JP2018502078A (ja) 2018-01-25
IL308119B2 (en) 2025-11-01
IL300202A (en) 2023-03-01
KR102549746B1 (ko) 2023-07-03
ES2948037T3 (es) 2023-08-30
SG11201704975SA (en) 2017-07-28
HK1245823A1 (en) 2018-08-31
IL300202B2 (en) 2024-04-01
KR20170095270A (ko) 2017-08-22

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