PL2354161T3 - Przeciwciało anty -NR10 i jego zastosowanie - Google Patents

Przeciwciało anty -NR10 i jego zastosowanie

Info

Publication number
PL2354161T3
PL2354161T3 PL09830463T PL09830463T PL2354161T3 PL 2354161 T3 PL2354161 T3 PL 2354161T3 PL 09830463 T PL09830463 T PL 09830463T PL 09830463 T PL09830463 T PL 09830463T PL 2354161 T3 PL2354161 T3 PL 2354161T3
Authority
PL
Poland
Prior art keywords
antibody
Prior art date
Application number
PL09830463T
Other languages
English (en)
Inventor
Taichi Kuramochi
Keiko Kasutani
Souhei Ohyama
Hiroyuki Tsunoda
Tomoyuki Igawa
Tatsuhiko Tachibana
Hirotake Shiraiwa
Keiko Esaki
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP2008/072152 external-priority patent/WO2009072604A1/ja
Priority claimed from PCT/JP2009/054941 external-priority patent/WO2010064456A1/ja
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of PL2354161T3 publication Critical patent/PL2354161T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Liquid Crystal (AREA)
PL09830463T 2008-12-05 2009-12-04 Przeciwciało anty -NR10 i jego zastosowanie PL2354161T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/JP2008/072152 WO2009072604A1 (ja) 2007-12-05 2008-12-05 抗nr10抗体、およびその利用
PCT/JP2009/054941 WO2010064456A1 (ja) 2008-12-05 2009-03-13 抗nr10抗体、およびその利用
EP09830463.7A EP2354161B1 (en) 2008-12-05 2009-12-04 Anti-nr10 antibody, and use thereof
PCT/JP2009/070376 WO2010064697A1 (ja) 2008-12-05 2009-12-04 抗nr10抗体、およびその利用

Publications (1)

Publication Number Publication Date
PL2354161T3 true PL2354161T3 (pl) 2016-01-29

Family

ID=42233344

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09830463T PL2354161T3 (pl) 2008-12-05 2009-12-04 Przeciwciało anty -NR10 i jego zastosowanie

Country Status (10)

Country Link
EP (2) EP2354161B1 (pl)
JP (1) JP2010210772A (pl)
KR (1) KR101271323B1 (pl)
BR (1) BRPI0906478B8 (pl)
DK (1) DK2354161T3 (pl)
ES (1) ES2552690T3 (pl)
PL (1) PL2354161T3 (pl)
PT (1) PT2354161E (pl)
RU (1) RU2487136C2 (pl)
WO (1) WO2010064697A1 (pl)

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EP3056568B1 (en) 2006-03-31 2021-09-15 Chugai Seiyaku Kabushiki Kaisha Methods for controlling blood pharmacokinetics of antibodies
JP5144499B2 (ja) 2006-03-31 2013-02-13 中外製薬株式会社 二重特異性抗体を精製するための抗体改変方法
PT2047863E (pt) 2006-06-08 2013-10-21 Chugai Pharmaceutical Co Ltd Prevenção ou tratamento para doença inflamatória
CN101874042B9 (zh) 2007-09-26 2019-01-01 中外制药株式会社 利用cdr的氨基酸取代来改变抗体等电点的方法
RU2526512C2 (ru) 2007-09-26 2014-08-20 Чугаи Сейяку Кабусики Кайся Модифицированная константная область антитела
EP2409990A4 (en) 2009-03-19 2013-01-23 Chugai Pharmaceutical Co Ltd VARIANT OF A CONSTANT ANTIBODY REGION
JP5717624B2 (ja) 2009-03-19 2015-05-13 中外製薬株式会社 抗体定常領域改変体
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WO2014208645A1 (ja) * 2013-06-28 2014-12-31 中外製薬株式会社 そう痒を伴う疾患に罹患した患者のｉｌ－３１アンタゴニストによる治療に対する応答を予測する方法
TW202515609A (zh) * 2015-04-14 2025-04-16 日商中外製藥股份有限公司 含有il-31拮抗劑作為有效成分之異位性皮膚炎的預防用及/或治療用醫藥組合物
KR102886159B1 (ko) 2015-04-14 2025-11-13 추가이 세이야쿠 가부시키가이샤 Il-31 안타고니스트를 유효 성분으로서 함유하는 아토피성 피부염의 예방용 및/또는 치료용 의약 조성물
BR112018009312A8 (pt) 2015-12-28 2019-02-26 Chugai Pharmaceutical Co Ltd método para promover eficiência de purificação de polipeptídeo contendo região de fc
PL234632B1 (pl) 2016-03-02 2020-03-31 Inst Immunologii I Terapii Doswiadczalnej Polskiej Akademii Nauk Przeciwciała oddziałujące z komórkami psich chłoniaków typu B i ich zastosowania
HRP20251101T1 (hr) 2018-02-09 2025-11-21 Galderma Holding SA Nemolizumab u liječenju atopijskog dermatitisa s umjerenom do teškom ekskoriacijom
CN112512480B (zh) 2018-05-21 2024-10-01 中外制药株式会社 被封入玻璃容器的冷冻干燥制剂
US11236157B2 (en) 2019-01-28 2022-02-01 Galderma Holding SA Treatment of skin lesions and pruritus in prurigo nodularis patients
AU2020252840B2 (en) 2019-04-02 2025-01-23 Chugai Seiyaku Kabushiki Kaisha Method of introducing target-specific foreign gene
MX2022005654A (es) 2019-11-20 2022-06-22 Chugai Pharmaceutical Co Ltd Preparacion que contiene anticuerpo.
TWI871349B (zh) * 2020-09-01 2025-02-01 日商中外製藥股份有限公司 含有il-31拮抗劑作為有效成分之透析搔癢症的預防用及/或治療用醫藥組合物
IL300694A (en) * 2020-09-01 2023-04-01 Chugai Pharmaceutical Co Ltd A pharmaceutical preparation for the prevention and/or treatment of dialysis pruritus that includes an IL-31 antagonist as an active ingredient
US20220411518A1 (en) 2021-04-07 2022-12-29 Galderma Holding S.A. Treatments for prurigo nodularis
EP4395657A1 (en) 2021-08-30 2024-07-10 Galderma Holding SA Treatments for atopic dermatitis
CN118613503A (zh) 2021-12-22 2024-09-06 中外制药株式会社 生物学活性降低的抗体变体
US20240141050A1 (en) 2022-09-02 2024-05-02 Galderma Holding S.A. Treatments for prurigo nodularis

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Also Published As

Publication number Publication date
RU2010126078A (ru) 2013-01-10
RU2487136C2 (ru) 2013-07-10
BRPI0906478B1 (pt) 2020-02-11
DK2354161T3 (en) 2015-09-14
BRPI0906478B8 (pt) 2021-05-25
KR20100091245A (ko) 2010-08-18
PT2354161E (pt) 2015-10-22
ES2552690T3 (es) 2015-12-01
EP2354161A4 (en) 2013-01-02
KR101271323B1 (ko) 2013-06-04
EP2354161B1 (en) 2015-08-12
WO2010064697A1 (ja) 2010-06-10
BRPI0906478A2 (pt) 2015-11-24
EP2354161A1 (en) 2011-08-10
JP2010210772A (ja) 2010-09-24
EP2949672A1 (en) 2015-12-02

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