DK2529621T3 - Inhibitorer af Brutons tyrosinkinase - Google Patents
Inhibitorer af Brutons tyrosinkinase Download PDFInfo
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- DK2529621T3 DK2529621T3 DK12166298.5T DK12166298T DK2529621T3 DK 2529621 T3 DK2529621 T3 DK 2529621T3 DK 12166298 T DK12166298 T DK 12166298T DK 2529621 T3 DK2529621 T3 DK 2529621T3
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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Claims (13)
1. l-(3-(4-Amino-3-(4-phenoxyphenyl)-l H-pyrazol[3,4-d]pyrimidin-l-yl)piperidin-l-yl)prop-2-en-l-on eller et farmaceutisk acceptabelt salt deraf til anvendelse til behandling af Waldenstroms makroglobulinæmi.
2. l-((R)-3-(4-amino-3-(4-phenoxyphenyl)-lH-pyrazol[3,4-d]pyrimidin-l-yl)piperidin-l-yl)prop-2-en-l-on til anvendelse ifølge krav 1 til behandling af Waldenstroms makroglobulinæmi.
3. Forbindelse til anvendelse ifølge enten 1 eller 2 ved oral indgivelse.
4. Farmaceutisk sammensætning ifølge et hvilket som helst af kravene 1 og 2 til anvendelse til behandling afen cancer hvilken omfatter en forbindelse ifølge et hvilket som helst af kravene 1 og 2.
5. Farmaceutisk sammensætning til anvendelse ifølge krav 4 til oral indgivelse.
6. Farmaceutisk sammensætning til anvendelse ifølge krav 5 hvilken er i en fast dosisform.
7. Farmaceutisk sammensætning til anvendelse ifølge krav 5 i form af en tablet.
8. Farmaceutisk sammensætning til anvendelse ifølge krav 5 i form af en pille.
9. Farmaceutisk sammensætning til anvendelse ifølge krav 5 i form af et pulver.
10. Farmaceutisk sammensætning til anvendelse ifølge krav 5 i form afen kapsel.
11. Farmaceutisk sammensætning til anvendelse ifølge krav 10 hvilken er en blød kapsel.
12. Farmaceutisk sammensætning til anvendelse ifølge krav 10 hvilken er en hård kapsel.
13. Farmaceutisk sammensætning til anvendelse ifølge krav 5 hvilken er en flydende formulering.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82672006P | 2006-09-22 | 2006-09-22 | |
US82859006P | 2006-10-06 | 2006-10-06 | |
EP06850039.6A EP2081435B1 (en) | 2006-09-22 | 2006-12-28 | Inhibitors of bruton's tyrosine kinase |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2529621T3 true DK2529621T3 (da) | 2017-01-16 |
Family
ID=39225888
Family Applications (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK12166305.8T DK2526934T3 (da) | 2006-09-22 | 2006-12-28 | Hæmmere af Brutons tyrosinkinase |
DK12166298.5T DK2529621T3 (da) | 2006-09-22 | 2006-12-28 | Inhibitorer af Brutons tyrosinkinase |
DK10155834.4T DK2201840T3 (da) | 2006-09-22 | 2006-12-28 | Hæmmere af Brutons tyrosinkinase |
DK12166301.7T DK2526933T3 (da) | 2006-09-22 | 2006-12-28 | Hæmmere af Brutons tyrosinkinase |
DK12166300.9T DK2526771T3 (da) | 2006-09-22 | 2006-12-28 | Hæmmere af Brutons tyrosinkinase |
DK06850039.6T DK2081435T3 (da) | 2006-09-22 | 2006-12-28 | Inhibitorer af bruton's tyrosinkinase |
DK12166302.5T DK2529622T3 (da) | 2006-09-22 | 2006-12-28 | Inhibitorer af bruton-tyrosinkinase |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK12166305.8T DK2526934T3 (da) | 2006-09-22 | 2006-12-28 | Hæmmere af Brutons tyrosinkinase |
Family Applications After (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK10155834.4T DK2201840T3 (da) | 2006-09-22 | 2006-12-28 | Hæmmere af Brutons tyrosinkinase |
DK12166301.7T DK2526933T3 (da) | 2006-09-22 | 2006-12-28 | Hæmmere af Brutons tyrosinkinase |
DK12166300.9T DK2526771T3 (da) | 2006-09-22 | 2006-12-28 | Hæmmere af Brutons tyrosinkinase |
DK06850039.6T DK2081435T3 (da) | 2006-09-22 | 2006-12-28 | Inhibitorer af bruton's tyrosinkinase |
DK12166302.5T DK2529622T3 (da) | 2006-09-22 | 2006-12-28 | Inhibitorer af bruton-tyrosinkinase |
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PL (8) | PL2526934T4 (da) |
PT (7) | PT2526771T (da) |
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