GB201309085D0 - Compounds - Google Patents

Compounds

Info

Publication number
GB201309085D0
GB201309085D0 GBGB1309085.7A GB201309085A GB201309085D0 GB 201309085 D0 GB201309085 D0 GB 201309085D0 GB 201309085 A GB201309085 A GB 201309085A GB 201309085 D0 GB201309085 D0 GB 201309085D0
Authority
GB
United Kingdom
Prior art keywords
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1309085.7A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Redx Pharna PLC
Original Assignee
Redx Pharna PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Redx Pharna PLC filed Critical Redx Pharna PLC
Priority to GBGB1309085.7A priority Critical patent/GB201309085D0/en
Publication of GB201309085D0 publication Critical patent/GB201309085D0/en
Priority to PCT/GB2014/051542 priority patent/WO2014188173A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
GBGB1309085.7A 2013-05-20 2013-05-20 Compounds Ceased GB201309085D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GBGB1309085.7A GB201309085D0 (en) 2013-05-20 2013-05-20 Compounds
PCT/GB2014/051542 WO2014188173A1 (en) 2013-05-20 2014-05-20 Pyrazolopyrimidine derivatives useful as inhibitors of bruton's tyrosine kinase

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1309085.7A GB201309085D0 (en) 2013-05-20 2013-05-20 Compounds

Publications (1)

Publication Number Publication Date
GB201309085D0 true GB201309085D0 (en) 2013-07-03

Family

ID=48747060

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1309085.7A Ceased GB201309085D0 (en) 2013-05-20 2013-05-20 Compounds

Country Status (2)

Country Link
GB (1) GB201309085D0 (en)
WO (1) WO2014188173A1 (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201410430D0 (en) 2014-06-11 2014-07-23 Redx Pharma Ltd Compounds
CN107207519B (en) * 2015-02-12 2019-11-08 正大天晴药业集团股份有限公司 Yi Bu replaces the preparation method of Buddhist nun
MA41828A (en) * 2015-03-27 2018-01-30 Pharmacyclics Llc CO-CRYSTALS OF A TYROSINE KINASE INHIBITOR FROM BRUTON
WO2016154998A1 (en) * 2015-04-03 2016-10-06 安润医药科技（苏州）有限公司 Pyrazolopyrimidine derivative, manufacturing method, pharmaceutical composition, and use thereof
CN106146511A (en) * 2015-04-03 2016-11-23 安润医药科技（苏州）有限公司 Pyrazolopyrimidine derivative, preparation method, pharmaceutical composition and purposes
CN105777759B (en) * 2016-04-29 2018-01-26 杭州和正医药有限公司 A kind of bruton's tyrosine kinase inhibitor
CN104844609B (en) * 2015-05-12 2016-07-13 杭州和正医药有限公司 The irreversible bruton's tyrosine kinase inhibitor of dibit point
MX2018003351A (en) * 2015-09-16 2018-09-17 Loxo Oncology Inc Pyrazolopyrimidine derivatives as btk inhibitors for the treatment of cancer.
AU2016373530B2 (en) 2015-12-16 2021-01-21 Loxo Oncology, Inc. Compounds useful as kinase inhibitors
US9630968B1 (en) 2015-12-23 2017-04-25 Arqule, Inc. Tetrahydropyranyl amino-pyrrolopyrimidinone and methods of use thereof
SI3394065T1 (en) * 2015-12-23 2021-08-31 Arqule, Inc. Tetrahydropyranyl amino-pyrrolopyrimidinone and methods of use thereof
CN106928231B (en) * 2015-12-31 2021-06-01 合肥中科普瑞昇生物医药科技有限公司 Novel EGFR wild type and mutant kinase inhibitors
AU2017208119B2 (en) 2016-01-15 2019-11-07 Pfizer Inc. 6,7,8,9-tetrahydro-5H-pyrido[2,3-d]azepine dopamine D3 ligands
CN108602834B (en) * 2016-02-05 2021-01-08 北京盛诺基医药科技股份有限公司 Bruton's tyrosine kinase inhibitor
WO2017163078A1 (en) 2016-03-24 2017-09-28 Mission Therapeutics Limited 1-cyano-pyrrolidine derivatives as dbu inhibitors
CN106146518A (en) * 2016-06-30 2016-11-23 苏州爱玛特生物科技有限公司 A kind of bruton's tyrosine kinase inhibitor intermediate and preparation method thereof
WO2018002958A1 (en) 2016-06-30 2018-01-04 Sun Pharma Advanced Research Company Limited Novel hydrazide containing compounds as btk inhibitors
MX2019002212A (en) 2016-08-24 2019-07-08 Arqule Inc Amino-pyrrolopyrimidinone compounds and methods of use thereof.
GB201616511D0 (en) 2016-09-29 2016-11-16 Mission Therapeutics Limited Novel compounds
GB201616627D0 (en) 2016-09-30 2016-11-16 Mission Therapeutics Limited Novel compounds
EP3543239A4 (en) 2016-11-15 2019-09-25 Hangzhou Hertz Pharmaceutical Co., Ltd. Selective bruton's tyrosine kinase inhibitor and use thereof
CN109369654A (en) * 2018-11-20 2019-02-22 山东大学 1,3- bis- substituted-4-amino Pyrazolopyrimidines and its preparation method and application
WO2021038540A1 (en) 2019-08-31 2021-03-04 Sun Pharma Advanced Research Company Limited Cycloalkylidene carboxylic acids and derivatives as btk inhibitors
JP7011638B2 (en) * 2019-12-16 2022-02-10 アークル インコーポレイテッド Tetrahydropyranylamino-pyrrolopyrimidinone and how to use it
CN113214265B (en) * 2020-01-21 2023-07-07 江苏先声药业有限公司 Pyrimidine five-membered ring compound
RU2747991C1 (en) * 2020-02-18 2021-05-18 Аркьюл, Инк. Tetrahydropyranyl amino-pyrrolopyrimidinone and methods of its use
EP4118086A1 (en) * 2020-03-12 2023-01-18 Fochon Biosciences, Ltd. Compounds useful as kinase inhibitors
US20240100172A1 (en) 2020-12-21 2024-03-28 Hangzhou Jijing Pharmaceutical Technology Limited Methods and compounds for targeted autophagy
CN114761410B (en) * 2021-04-06 2023-08-25 广州必贝特医药股份有限公司 Pyrrolopyrimidinone compounds and application thereof
WO2022213932A1 (en) * 2021-04-06 2022-10-13 广州必贝特医药股份有限公司 Pyrrolopyrimidinone compound and application thereof
CN115894500A (en) * 2022-11-02 2023-04-04 中国药科大学 Compound serving as BTK kinase inhibitor and preparation method and application thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2526934T3 (en) 2006-09-22 2016-03-07 Pharmacyclics Llc Inhibitors of Bruton's tyrosine kinase
ES2403546T3 (en) 2006-11-03 2013-05-20 Pharmacyclics, Inc. Bruton tyrosine kinase activity probe and method of use
EP2560007A1 (en) 2007-03-28 2013-02-20 Pharmacyclics, Inc. Identification of bruton's tyrosine kinase inhibitors
US8338439B2 (en) 2008-06-27 2012-12-25 Celgene Avilomics Research, Inc. 2,4-disubstituted pyrimidines useful as kinase inhibitors
KR20110025224A (en) 2008-06-27 2011-03-09 아빌라 테라퓨틱스, 인크. Heteroaryl compounds and uses thereof
US8426428B2 (en) 2008-12-05 2013-04-23 Principia Biopharma, Inc. EGFR kinase knockdown via electrophilically enhanced inhibitors
US7741330B1 (en) 2009-10-12 2010-06-22 Pharmacyclics, Inc. Pyrazolo-pyrimidine inhibitors of Bruton's tyrosine kinase
MY191929A (en) 2010-06-03 2022-07-18 Pharmacyclics Llc The use of inhibitors of bruton's tyrosine kinase (btk)
KR102052670B1 (en) 2011-05-17 2019-12-06 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 Kinase inhibitors
EP2710005B1 (en) 2011-05-17 2016-10-05 Principia Biopharma Inc. Tyrosine kinase inhibitors
CA2841080A1 (en) 2011-07-13 2013-01-17 Pharmacyclics, Inc. Inhibitors of bruton's tyrosine kinase
US8377946B1 (en) * 2011-12-30 2013-02-19 Pharmacyclics, Inc. Pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine compounds as kinase inhibitors

Also Published As

Publication number Publication date
WO2014188173A1 (en) 2014-11-27

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)