US2008526A
(en)
|
1932-11-03 |
1935-07-16 |
Wappler Frederick Charles |
Method and means for treating living tissue
|
US3467096A
(en)
|
1966-04-12 |
1969-09-16 |
Ferrell S Horn |
Multiple hypodermic syringe arrangement
|
BE757653A
(fr)
|
1969-10-21 |
1971-04-16 |
Ugine Kuhlmann |
Nouveaux medicaments derives d'acides nucleiques et procedes pour leur preparation
|
BE786542A
(fr)
|
1971-07-22 |
1973-01-22 |
Dow Corning |
Dispositif d'aspiration permettant d'obtenir des echantillons de cellules
|
US3906092A
(en)
|
1971-11-26 |
1975-09-16 |
Merck & Co Inc |
Stimulation of antibody response
|
US4270537A
(en)
|
1979-11-19 |
1981-06-02 |
Romaine Richard A |
Automatic hypodermic syringe
|
US4399216A
(en)
|
1980-02-25 |
1983-08-16 |
The Trustees Of Columbia University |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
US4458066A
(en)
|
1980-02-29 |
1984-07-03 |
University Patents, Inc. |
Process for preparing polynucleotides
|
US5132418A
(en)
|
1980-02-29 |
1992-07-21 |
University Patents, Inc. |
Process for preparing polynucleotides
|
US4500707A
(en)
|
1980-02-29 |
1985-02-19 |
University Patents, Inc. |
Nucleosides useful in the preparation of polynucleotides
|
US4411657A
(en)
|
1980-05-19 |
1983-10-25 |
Anibal Galindo |
Hypodermic needle
|
US4668777A
(en)
|
1981-03-27 |
1987-05-26 |
University Patents, Inc. |
Phosphoramidite nucleoside compounds
|
US4973679A
(en)
|
1981-03-27 |
1990-11-27 |
University Patents, Inc. |
Process for oligonucleo tide synthesis using phosphormidite intermediates
|
US4415732A
(en)
|
1981-03-27 |
1983-11-15 |
University Patents, Inc. |
Phosphoramidite compounds and processes
|
US4401796A
(en)
|
1981-04-30 |
1983-08-30 |
City Of Hope Research Institute |
Solid-phase synthesis of polynucleotides
|
US4373071A
(en)
|
1981-04-30 |
1983-02-08 |
City Of Hope Research Institute |
Solid-phase synthesis of polynucleotides
|
US4474569A
(en)
|
1982-06-28 |
1984-10-02 |
Denver Surgical Developments, Inc. |
Antenatal shunt
|
US4737462A
(en)
|
1982-10-19 |
1988-04-12 |
Cetus Corporation |
Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
|
US4588585A
(en)
|
1982-10-19 |
1986-05-13 |
Cetus Corporation |
Human recombinant cysteine depleted interferon-β muteins
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
US4579849A
(en)
|
1984-04-06 |
1986-04-01 |
Merck & Co., Inc. |
N-alkylguanine acyclonucleosides as antiviral agents
|
US4957735A
(en)
|
1984-06-12 |
1990-09-18 |
The University Of Tennessee Research Corporation |
Target-sensitive immunoliposomes- preparation and characterization
|
US4959314A
(en)
|
1984-11-09 |
1990-09-25 |
Cetus Corporation |
Cysteine-depleted muteins of biologically active proteins
|
US5036006A
(en)
|
1984-11-13 |
1991-07-30 |
Cornell Research Foundation, Inc. |
Method for transporting substances into living cells and tissues and apparatus therefor
|
US5116943A
(en)
|
1985-01-18 |
1992-05-26 |
Cetus Corporation |
Oxidation-resistant muteins of Il-2 and other protein
|
CA1288073C
(en)
|
1985-03-07 |
1991-08-27 |
Paul G. Ahlquist |
Rna transformation vector
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
EP0204401A1
(en)
|
1985-04-09 |
1986-12-10 |
Biogen, Inc. |
Method of improving the yield of polypeptides produced in a host cell by stabilizing mRNA
|
US5017691A
(en)
|
1986-07-03 |
1991-05-21 |
Schering Corporation |
Mammalian interleukin-4
|
US5153319A
(en)
|
1986-03-31 |
1992-10-06 |
University Patents, Inc. |
Process for preparing polynucleotides
|
US4879111A
(en)
|
1986-04-17 |
1989-11-07 |
Cetus Corporation |
Treatment of infections with lymphokines
|
CA1283827C
(en)
|
1986-12-18 |
1991-05-07 |
Giorgio Cirelli |
Appliance for injection of liquid formulations
|
GB8704027D0
(en)
|
1987-02-20 |
1987-03-25 |
Owen Mumford Ltd |
Syringe needle combination
|
US4941880A
(en)
|
1987-06-19 |
1990-07-17 |
Bioject, Inc. |
Pre-filled ampule and non-invasive hypodermic injection device assembly
|
US4940460A
(en)
|
1987-06-19 |
1990-07-10 |
Bioject, Inc. |
Patient-fillable and non-invasive hypodermic injection device assembly
|
US4790824A
(en)
|
1987-06-19 |
1988-12-13 |
Bioject, Inc. |
Non-invasive hypodermic injection device
|
WO1989001050A1
(en)
|
1987-07-31 |
1989-02-09 |
The Board Of Trustees Of The Leland Stanford Junior University |
Selective amplification of target polynucleotide sequences
|
US6090591A
(en)
|
1987-07-31 |
2000-07-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Selective amplification of target polynucleotide sequences
|
JP2846018B2
(ja)
|
1988-01-21 |
1999-01-13 |
ジェネンテク,インコーポレイテッド |
核酸配列の増幅および検出
|
CA1340807C
(en)
|
1988-02-24 |
1999-11-02 |
Lawrence T. Malek |
Nucleic acid amplification process
|
JP2650159B2
(ja)
|
1988-02-24 |
1997-09-03 |
アクゾ・ノベル・エヌ・ベー |
核酸増幅方法
|
AU3353989A
(en)
|
1988-03-04 |
1989-09-22 |
Cancer Research Campaign Technology Limited |
Improvements relating to antigens
|
US5339163A
(en)
|
1988-03-16 |
1994-08-16 |
Canon Kabushiki Kaisha |
Automatic exposure control device using plural image plane detection areas
|
EP0362371A4
(en)
|
1988-04-15 |
1990-10-24 |
Protein Design Labs, Inc. |
Il-2 receptor-specific chimeric antibodies
|
US5168038A
(en)
|
1988-06-17 |
1992-12-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
In situ transcription in cells and tissues
|
US5021335A
(en)
|
1988-06-17 |
1991-06-04 |
The Board Of Trustees Of The Leland Stanford Junior University |
In situ transcription in cells and tissues
|
US5130238A
(en)
|
1988-06-24 |
1992-07-14 |
Cangene Corporation |
Enhanced nucleic acid amplification process
|
US5759802A
(en)
|
1988-10-26 |
1998-06-02 |
Tonen Corporation |
Production of human serum alubumin A
|
FR2638359A1
(fr)
|
1988-11-03 |
1990-05-04 |
Tino Dalto |
Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
|
US5262530A
(en)
|
1988-12-21 |
1993-11-16 |
Applied Biosystems, Inc. |
Automated system for polynucleotide synthesis and purification
|
US5047524A
(en)
|
1988-12-21 |
1991-09-10 |
Applied Biosystems, Inc. |
Automated system for polynucleotide synthesis and purification
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
US6867195B1
(en)
|
1989-03-21 |
2005-03-15 |
Vical Incorporated |
Lipid-mediated polynucleotide administration to reduce likelihood of subject's becoming infected
|
US6673776B1
(en)
|
1989-03-21 |
2004-01-06 |
Vical Incorporated |
Expression of exogenous polynucleotide sequences in a vertebrate, mammal, fish, bird or human
|
US5693622A
(en)
|
1989-03-21 |
1997-12-02 |
Vical Incorporated |
Expression of exogenous polynucleotide sequences cardiac muscle of a mammal
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
US6214804B1
(en)
|
1989-03-21 |
2001-04-10 |
Vical Incorporated |
Induction of a protective immune response in a mammal by injecting a DNA sequence
|
DK0465529T3
(da)
|
1989-03-21 |
1998-10-05 |
Vical Inc |
Ekspression af exogene polynukleotidsekvenser i et hvirveldyr
|
US5012818A
(en)
|
1989-05-04 |
1991-05-07 |
Joishy Suresh K |
Two in one bone marrow surgical needle
|
IE66597B1
(en)
|
1989-05-10 |
1996-01-24 |
Akzo Nv |
Method for the synthesis of ribonucleic acid (RNA)
|
US5332671A
(en)
|
1989-05-12 |
1994-07-26 |
Genetech, Inc. |
Production of vascular endothelial cell growth factor and DNA encoding same
|
US5240855A
(en)
|
1989-05-12 |
1993-08-31 |
Pioneer Hi-Bred International, Inc. |
Particle gun
|
CA2020958C
(en)
|
1989-07-11 |
2005-01-11 |
Daniel L. Kacian |
Nucleic acid sequence amplification methods
|
US5545522A
(en)
|
1989-09-22 |
1996-08-13 |
Van Gelder; Russell N. |
Process for amplifying a target polynucleotide sequence using a single primer-promoter complex
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
US5215899A
(en)
|
1989-11-09 |
1993-06-01 |
Miles Inc. |
Nucleic acid amplification employing ligatable hairpin probe and transcription
|
NO904633L
(no)
|
1989-11-09 |
1991-05-10 |
Molecular Diagnostics Inc |
Amplifikasjon av nukleinsyrer ved transkriberbar haarnaalsprobe.
|
US5312335A
(en)
|
1989-11-09 |
1994-05-17 |
Bioject Inc. |
Needleless hypodermic injection device
|
US5064413A
(en)
|
1989-11-09 |
1991-11-12 |
Bioject, Inc. |
Needleless hypodermic injection device
|
US5633076A
(en)
|
1989-12-01 |
1997-05-27 |
Pharming Bv |
Method of producing a transgenic bovine or transgenic bovine embryo
|
US5697901A
(en)
|
1989-12-14 |
1997-12-16 |
Elof Eriksson |
Gene delivery by microneedle injection
|
US5194370A
(en)
|
1990-05-16 |
1993-03-16 |
Life Technologies, Inc. |
Promoter ligation activated transcription amplification of nucleic acid sequences
|
EP0542874A4
(en)
|
1990-07-25 |
1994-05-11 |
Syngene Inc |
Circular extension for generating multiple nucleic acid complements
|
US5190521A
(en)
|
1990-08-22 |
1993-03-02 |
Tecnol Medical Products, Inc. |
Apparatus and method for raising a skin wheal and anesthetizing skin
|
US6140496A
(en)
|
1990-10-09 |
2000-10-31 |
Benner; Steven Albert |
Precursors for deoxyribonucleotides containing non-standard nucleosides
|
US5527288A
(en)
|
1990-12-13 |
1996-06-18 |
Elan Medical Technologies Limited |
Intradermal drug delivery device and method for intradermal delivery of drugs
|
US6100024A
(en)
|
1991-02-08 |
2000-08-08 |
Promega Corporation |
Methods and compositions for nucleic acid detection by target extension and probe amplification
|
DE07012626T1
(de)
|
1991-03-18 |
2010-01-21 |
New York University |
Monoklonale und chimäre Antikörper gegen humanen Tumornekrosefaktor
|
US5426180A
(en)
|
1991-03-27 |
1995-06-20 |
Research Corporation Technologies, Inc. |
Methods of making single-stranded circular oligonucleotides
|
US5795965A
(en)
|
1991-04-25 |
1998-08-18 |
Chugai Seiyaku Kabushiki Kaisha |
Reshaped human to human interleukin-6 receptor
|
US5169766A
(en)
|
1991-06-14 |
1992-12-08 |
Life Technologies, Inc. |
Amplification of nucleic acid molecules
|
US5199441A
(en)
|
1991-08-20 |
1993-04-06 |
Hogle Hugh H |
Fine needle aspiration biopsy apparatus and method
|
GB9118204D0
(en)
|
1991-08-23 |
1991-10-09 |
Weston Terence E |
Needle-less injector
|
SE9102652D0
(sv)
|
1991-09-13 |
1991-09-13 |
Kabi Pharmacia Ab |
Injection needle arrangement
|
US5298422A
(en)
|
1991-11-06 |
1994-03-29 |
Baylor College Of Medicine |
Myogenic vector systems
|
US5824307A
(en)
|
1991-12-23 |
1998-10-20 |
Medimmune, Inc. |
Human-murine chimeric antibodies against respiratory syncytial virus
|
WO1993014778A1
(en)
|
1992-01-23 |
1993-08-05 |
Vical, Inc. |
Ex vivo gene transfer
|
US5328483A
(en)
|
1992-02-27 |
1994-07-12 |
Jacoby Richard M |
Intradermal injection device with medication and needle guard
|
JP3368603B2
(ja)
|
1992-02-28 |
2003-01-20 |
オリンパス光学工業株式会社 |
遺伝子治療用処置具
|
ES2149768T3
(es)
|
1992-03-25 |
2000-11-16 |
Immunogen Inc |
Conjugados de agentes enlazantes de celulas derivados de cc-1065.
|
US6174666B1
(en)
|
1992-03-27 |
2001-01-16 |
The United States Of America As Represented By The Department Of Health And Human Services |
Method of eliminating inhibitory/instability regions from mRNA
|
US6132419A
(en)
|
1992-05-22 |
2000-10-17 |
Genetronics, Inc. |
Electroporetic gene and drug therapy
|
US5514545A
(en)
|
1992-06-11 |
1996-05-07 |
Trustees Of The University Of Pennsylvania |
Method for characterizing single cells based on RNA amplification for diagnostics and therapeutics
|
US6670178B1
(en)
|
1992-07-10 |
2003-12-30 |
Transkaryotic Therapies, Inc. |
In Vivo production and delivery of insulinotropin for gene therapy
|
US5383851A
(en)
|
1992-07-24 |
1995-01-24 |
Bioject Inc. |
Needleless hypodermic injection device
|
DK0652973T3
(da)
|
1992-07-31 |
1997-09-15 |
Behringwerke Ag |
Fremgangsmåde til indføring af definerede sekvenser ved 3-enden af polynukleotider
|
US5273525A
(en)
|
1992-08-13 |
1993-12-28 |
Btx Inc. |
Injection and electroporation apparatus for drug and gene delivery
|
US5569189A
(en)
|
1992-09-28 |
1996-10-29 |
Equidyne Systems, Inc. |
hypodermic jet injector
|
US5334144A
(en)
|
1992-10-30 |
1994-08-02 |
Becton, Dickinson And Company |
Single use disposable needleless injector
|
WO1994009838A1
(en)
|
1992-11-04 |
1994-05-11 |
Denver Biomaterials, Inc. |
Apparatus for removal of pleural effusion fluid
|
DK0669836T3
(da)
|
1992-11-13 |
1996-10-14 |
Idec Pharma Corp |
Terapeutisk anvendelse af kimære og radioaktivt mærkede antistoffer og humant B-lymfocytbegrænset differentieringsantigen til behandling af B-cellelymfom
|
US5736137A
(en)
|
1992-11-13 |
1998-04-07 |
Idec Pharmaceuticals Corporation |
Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
|
EP0678122B1
(en)
|
1993-01-12 |
1999-07-28 |
Biogen, Inc. |
Recombinant anti-vla4 antibody molecules
|
FR2703253B1
(fr)
|
1993-03-30 |
1995-06-23 |
Centre Nat Rech Scient |
Applicateur d'impulsions electriques pour traitement de tissus biologiques.
|
US7135312B2
(en)
|
1993-04-15 |
2006-11-14 |
University Of Rochester |
Circular DNA vectors for synthesis of RNA and DNA
|
US5773244A
(en)
|
1993-05-19 |
1998-06-30 |
Regents Of The University Of California |
Methods of making circular RNA
|
US5851829A
(en)
|
1993-07-16 |
1998-12-22 |
Dana-Farber Cancer Institute |
Method of intracellular binding of target molecules
|
US5672491A
(en)
|
1993-09-20 |
1997-09-30 |
The Leland Stanford Junior University |
Recombinant production of novel polyketides
|
US6432711B1
(en)
|
1993-11-03 |
2002-08-13 |
Diacrin, Inc. |
Embryonic stem cells capable of differentiating into desired cell lines
|
US6096503A
(en)
|
1993-11-12 |
2000-08-01 |
The Scripps Research Institute |
Method for simultaneous identification of differentially expresses mRNAs and measurement of relative concentrations
|
US5840299A
(en)
|
1994-01-25 |
1998-11-24 |
Athena Neurosciences, Inc. |
Humanized antibodies against leukocyte adhesion molecule VLA-4
|
US7435802B2
(en)
|
1994-01-25 |
2008-10-14 |
Elan Pharaceuticals, Inc. |
Humanized anti-VLA4 immunoglobulins
|
ATE272113T1
(de)
|
1994-02-16 |
2004-08-15 |
Crucell Holland Bv |
Melanoma-assoziierte antigene, epitope davon und impstoffe gegen melanoma
|
WO1995024176A1
(en)
|
1994-03-07 |
1995-09-14 |
Bioject, Inc. |
Ampule filling device
|
IL112820A0
(en)
|
1994-03-07 |
1995-05-26 |
Merck & Co Inc |
Coordinate in vivo gene expression
|
US5466220A
(en)
|
1994-03-08 |
1995-11-14 |
Bioject, Inc. |
Drug vial mixing and transfer device
|
AU704549B2
(en)
|
1994-03-18 |
1999-04-29 |
Lynx Therapeutics, Inc. |
Oligonucleotide N3'-P5' phosphoramidates: synthesis and compounds; hybridization and nuclease resistance properties
|
WO1995026204A1
(en)
|
1994-03-25 |
1995-10-05 |
Isis Pharmaceuticals, Inc. |
Immune stimulation by phosphorothioate oligonucleotide analogs
|
US5457041A
(en)
|
1994-03-25 |
1995-10-10 |
Science Applications International Corporation |
Needle array and method of introducing biological substances into living cells using the needle array
|
US6074642A
(en)
|
1994-05-02 |
2000-06-13 |
Alexion Pharmaceuticals, Inc. |
Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis
|
PT759993E
(pt)
|
1994-05-18 |
2007-08-10 |
Bayer Bioscience Gmbh |
''sequências de dna que codificam para enzimas capazes de facilitar a síntese de alfa-1,4-glucanos lineares em plantas, fungos e microrganismos''
|
CA2191362A1
(en)
|
1994-06-02 |
1995-12-14 |
Mark Selby |
Nucleic acid immunization using a virus-based infection/transfection system
|
GB9412230D0
(en)
|
1994-06-17 |
1994-08-10 |
Celltech Ltd |
Interleukin-5 specific recombiant antibodies
|
US6239116B1
(en)
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
CA2195557C
(en)
|
1994-08-12 |
2006-10-17 |
Shui-On Leung |
Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells
|
US5665545A
(en)
|
1994-11-28 |
1997-09-09 |
Akzo Nobel N.V. |
Terminal repeat amplification method
|
US5641665A
(en)
|
1994-11-28 |
1997-06-24 |
Vical Incorporated |
Plasmids suitable for IL-2 expression
|
US5588960A
(en)
|
1994-12-01 |
1996-12-31 |
Vidamed, Inc. |
Transurethral needle delivery device with cystoscope and method for treatment of urinary incontinence
|
US5807718A
(en)
|
1994-12-02 |
1998-09-15 |
The Scripps Research Institute |
Enzymatic DNA molecules
|
WO1996021023A1
(en)
|
1995-01-06 |
1996-07-11 |
Centrum Voor Plantenveredelings- En Reproduktieonderzoek (Cpro - Dlo) |
Dna sequences encoding carbohydrate polymer synthesizing enzymes and method for producing transgenic plants
|
US5599302A
(en)
|
1995-01-09 |
1997-02-04 |
Medi-Ject Corporation |
Medical injection system and method, gas spring thereof and launching device using gas spring
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
US5824497A
(en)
|
1995-02-10 |
1998-10-20 |
Mcmaster University |
High efficiency translation of mRNA molecules
|
DE69629326D1
(de)
|
1995-02-15 |
2003-09-11 |
Joseph Eldor |
Spinalnadel mit mehreren Löchern
|
EP0735144B1
(en)
|
1995-03-28 |
2002-06-05 |
Japan Science and Technology Corporation |
Method for molecular indexing of genes using restriction enzymes
|
US5869230A
(en)
|
1995-03-30 |
1999-02-09 |
Beth Israel Hospital Association |
Gene transfer into the kidney
|
US5986054A
(en)
|
1995-04-28 |
1999-11-16 |
The Hospital For Sick Children, Hsc Research And Development Limited Partnership |
Genetic sequences and proteins related to alzheimer's disease
|
FR2733762B1
(fr)
|
1995-05-02 |
1997-08-01 |
Genset Sa |
Methode de couplage specifique de la coiffe de l'extremite 5' d'un fragment d'arnm et preparation d'arnm et d'adnc complet
|
US5700642A
(en)
|
1995-05-22 |
1997-12-23 |
Sri International |
Oligonucleotide sizing using immobilized cleavable primers
|
US5730723A
(en)
|
1995-10-10 |
1998-03-24 |
Visionary Medical Products Corporation, Inc. |
Gas pressured needle-less injection device and method
|
US6111095A
(en)
|
1995-06-07 |
2000-08-29 |
Merck & Co., Inc. |
Capped synthetic RNA, analogs, and aptamers
|
US6051429A
(en)
|
1995-06-07 |
2000-04-18 |
Life Technologies, Inc. |
Peptide-enhanced cationic lipid transfections
|
US5889136A
(en)
|
1995-06-09 |
1999-03-30 |
The Regents Of The University Of Colorado |
Orthoester protecting groups in RNA synthesis
|
US5766903A
(en)
|
1995-08-23 |
1998-06-16 |
University Technology Corporation |
Circular RNA and uses thereof
|
US6265389B1
(en)
|
1995-08-31 |
2001-07-24 |
Alkermes Controlled Therapeutics, Inc. |
Microencapsulation and sustained release of oligonucleotides
|
AU7073096A
(en)
|
1995-09-19 |
1997-04-09 |
University Of Massachusetts |
Inhibited biological degradation of oligodeoxynucleotides
|
US5830879A
(en)
|
1995-10-02 |
1998-11-03 |
St. Elizabeth's Medical Center Of Boston, Inc. |
Treatment of vascular injury using vascular endothelial growth factor
|
US6265387B1
(en)
|
1995-10-11 |
2001-07-24 |
Mirus, Inc. |
Process of delivering naked DNA into a hepatocyte via bile duct
|
EP0771873A3
(en)
|
1995-10-27 |
1998-03-04 |
Takeda Chemical Industries, Ltd. |
Neuronal cell-specific receptor protein
|
CU22584A1
(es)
|
1995-11-17 |
1999-11-03 |
Centro Inmunologia Molecular |
Composiciones farmacéuticas que contienen un anticuerpo monoclonal que reconoce el antígeno de diferenciación leucocitario humano cd6 y sus usos para el diagnóstico y tratamiento de la psoriasis
|
US6090382A
(en)
|
1996-02-09 |
2000-07-18 |
Basf Aktiengesellschaft |
Human antibodies that bind human TNFα
|
US5962271A
(en)
|
1996-01-03 |
1999-10-05 |
Cloutech Laboratories, Inc. |
Methods and compositions for generating full-length cDNA having arbitrary nucleotide sequence at the 3'-end
|
US5893397A
(en)
|
1996-01-12 |
1999-04-13 |
Bioject Inc. |
Medication vial/syringe liquid-transfer apparatus
|
US6395292B2
(en)
|
1996-02-02 |
2002-05-28 |
Alza Corporation |
Sustained delivery of an active agent using an implantable system
|
US6261584B1
(en)
|
1996-02-02 |
2001-07-17 |
Alza Corporation |
Sustained delivery of an active agent using an implantable system
|
WO1997030064A1
(en)
|
1996-02-16 |
1997-08-21 |
Stichting Rega Vzw |
Hexitol containing oligonucleotides and their use in antisense strategies
|
US6534312B1
(en)
|
1996-02-22 |
2003-03-18 |
Merck & Co., Inc. |
Vaccines comprising synthetic genes
|
US6090391A
(en)
|
1996-02-23 |
2000-07-18 |
Aviron |
Recombinant tryptophan mutants of influenza
|
US6300487B1
(en)
|
1996-03-19 |
2001-10-09 |
Cell Therapuetics, Inc. |
Mammalian lysophosphatidic acid acyltransferase
|
SE9601245D0
(sv)
|
1996-03-29 |
1996-03-29 |
Pharmacia Ab |
Chimeric superantigens and their use
|
TW517061B
(en)
|
1996-03-29 |
2003-01-11 |
Pharmacia & Amp Upjohn Ab |
Modified/chimeric superantigens and their use
|
GB9607549D0
(en)
|
1996-04-11 |
1996-06-12 |
Weston Medical Ltd |
Spring-powered dispensing device
|
US5712127A
(en)
|
1996-04-29 |
1998-01-27 |
Genescape Inc. |
Subtractive amplification
|
US5853719A
(en)
|
1996-04-30 |
1998-12-29 |
Duke University |
Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA
|
US7329741B2
(en)
|
1996-06-05 |
2008-02-12 |
Chiron Corporation |
Polynucleotides that hybridize to DP-75 and their use
|
DE69739524D1
(de)
|
1996-06-05 |
2009-09-17 |
Novartis Vaccines & Diagnostic |
Dp-75 kodierende dna und verfahren zu ihrer verwendung
|
AU728422B2
(en)
|
1996-06-21 |
2001-01-11 |
Merck & Co., Inc. |
Vaccines comprising synthetic genes
|
JP2002515786A
(ja)
|
1996-06-28 |
2002-05-28 |
ソントラ メディカル,エル.ピー. |
経皮輸送の超音波増強
|
US5677124A
(en)
|
1996-07-03 |
1997-10-14 |
Ambion, Inc. |
Ribonuclease resistant viral RNA standards
|
US5939262A
(en)
|
1996-07-03 |
1999-08-17 |
Ambion, Inc. |
Ribonuclease resistant RNA preparation and utilization
|
US7288266B2
(en)
|
1996-08-19 |
2007-10-30 |
United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Liposome complexes for increased systemic delivery
|
US5849546A
(en)
|
1996-09-13 |
1998-12-15 |
Epicentre Technologies Corporation |
Methods for using mutant RNA polymerases with reduced discrimination between non-canonical and canonical nucleoside triphosphates
|
US6114148C1
(en)
|
1996-09-20 |
2012-05-01 |
Gen Hospital Corp |
High level expression of proteins
|
ES2263181T5
(es)
|
1996-09-24 |
2011-04-07 |
Genentech, Inc. |
Una familia de genes que codifican péptidos relacionados con la apoptosis, péptidos codificados por ellos y los métodos de uso de los mismos.
|
US6214966B1
(en)
|
1996-09-26 |
2001-04-10 |
Shearwater Corporation |
Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
|
WO1998016247A1
(en)
|
1996-10-11 |
1998-04-23 |
The Regents Of The University Of California |
Immunostimulatory polynucleotide/immunomodulatory molecule conjugates
|
EP0839912A1
(en)
|
1996-10-30 |
1998-05-06 |
Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) |
Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
|
GB9623051D0
(en)
|
1996-11-06 |
1997-01-08 |
Schacht Etienne H |
Delivery of DNA to target cells in biological systems
|
US5980887A
(en)
|
1996-11-08 |
1999-11-09 |
St. Elizabeth's Medical Center Of Boston |
Methods for enhancing angiogenesis with endothelial progenitor cells
|
US5759179A
(en)
|
1996-12-31 |
1998-06-02 |
Johnson & Johnson Medical, Inc. |
Needle and valve assembly for use with a catheter
|
EP1712623B1
(en)
|
1997-01-21 |
2011-10-19 |
The General Hospital Corporation |
Selection of proteins using RNA-protein fusions
|
EP0855184A1
(en)
|
1997-01-23 |
1998-07-29 |
Grayson B. Dr. Lipford |
Pharmaceutical composition comprising a polynucleotide and an antigen especially for vaccination
|
US6251665B1
(en)
|
1997-02-07 |
2001-06-26 |
Cem Cezayirli |
Directed maturation of stem cells and production of programmable antigen presenting dentritic cells therefrom
|
US6696291B2
(en)
|
1997-02-07 |
2004-02-24 |
Merck & Co., Inc. |
Synthetic HIV gag genes
|
CA2280195A1
(en)
|
1997-02-07 |
1998-08-13 |
Merck & Co., Inc. |
Synthetic hiv gag genes
|
US6228640B1
(en)
|
1997-02-07 |
2001-05-08 |
Cem Cezayirli |
Programmable antigen presenting cell of CD34 lineage
|
US6406705B1
(en)
|
1997-03-10 |
2002-06-18 |
University Of Iowa Research Foundation |
Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
|
US6306393B1
(en)
|
1997-03-24 |
2001-10-23 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
US6261281B1
(en)
|
1997-04-03 |
2001-07-17 |
Electrofect As |
Method for genetic immunization and introduction of molecules into skeletal muscle and immune cells
|
US5914269A
(en)
|
1997-04-04 |
1999-06-22 |
Isis Pharmaceuticals, Inc. |
Oligonucleotide inhibition of epidermal growth factor receptor expression
|
WO1998047913A2
(en)
|
1997-04-18 |
1998-10-29 |
The University Of Medicine And Dentistry Of New Jersey |
Inhibition of hiv-1 replication by a tat rna-binding domain peptide analog
|
US5958688A
(en)
|
1997-04-28 |
1999-09-28 |
The Trustees Of The University Of Pennsylvania |
Characterization of mRNA patterns in neurites and single cells for medical diagnosis and therapeutics
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
US5989911A
(en)
|
1997-05-09 |
1999-11-23 |
University Of Massachusetts |
Site-specific synthesis of pseudouridine in RNA
|
US5993412A
(en)
|
1997-05-19 |
1999-11-30 |
Bioject, Inc. |
Injection apparatus
|
US6124091A
(en)
|
1997-05-30 |
2000-09-26 |
Research Corporation Technologies, Inc. |
Cell growth-controlling oligonucleotides
|
US6589940B1
(en)
|
1997-06-06 |
2003-07-08 |
Dynavax Technologies Corporation |
Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
|
EP0986572B2
(en)
|
1997-06-06 |
2007-06-13 |
Dynavax Technologies Corporation |
Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
|
JP2002510319A
(ja)
|
1997-07-01 |
2002-04-02 |
アイシス・ファーマシューティカルス・インコーポレーテッド |
オリゴヌクレオチドの消化管を介したデリバリーのための組成物及び方法
|
US5994511A
(en)
|
1997-07-02 |
1999-11-30 |
Genentech, Inc. |
Anti-IgE antibodies and methods of improving polypeptides
|
AU748097B2
(en)
|
1997-07-21 |
2002-05-30 |
Active Biotech Ab |
Directed cytolysis of target cells, agents and compositions causing cytolysis, and compounds that can be used to produce the agents
|
EP1009441A1
(en)
|
1997-07-31 |
2000-06-21 |
St. Elizabeth's Medical Center of Boston, Inc. |
Method for the treatment of grafts
|
WO1999013896A1
(en)
|
1997-09-18 |
1999-03-25 |
The Trustees Of The University Of Pennsylvania |
Attenuated vif dna immunization cassettes for genetic vaccines
|
EP2292771A3
(en)
|
1997-09-19 |
2011-07-27 |
Life Technologies Corporation |
Sense mRNA therapy
|
US6004573A
(en)
|
1997-10-03 |
1999-12-21 |
Macromed, Inc. |
Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
|
EP1021548A1
(en)
|
1997-10-07 |
2000-07-26 |
University Of Maryland Biotechnology Institute |
Method for introducing and expressing rna in animal cells
|
EP1025244A2
(en)
|
1997-10-20 |
2000-08-09 |
Genzyme Transgenics Corporation |
NOVEL MODIFIED MSP-1 NUCLEIC ACID SEQUENCES AND METHODS FOR INCREASING mRNA LEVELS AND PROTEIN EXPRESSION IN CELL SYSTEMS
|
US6019747A
(en)
|
1997-10-21 |
2000-02-01 |
I-Flow Corporation |
Spring-actuated infusion syringe
|
AU1275899A
(en)
|
1997-10-24 |
1999-05-17 |
Megabios Corporation |
Methods for preparing polynucleotide transfection complexes
|
JP2001523480A
(ja)
|
1997-11-20 |
2001-11-27 |
バイカル インコーポレイテッド |
サイトカイン発現ポリヌクレオチドおよびそれらの組成物を用いた癌の処置
|
US7655777B2
(en)
|
1997-11-24 |
2010-02-02 |
Monsanto Technology Llc |
Nucleic acid molecules associated with the tocopherol pathway
|
AU1819499A
(en)
|
1997-12-12 |
1999-06-28 |
Samyang Corporation |
Positively-charged poly{alpha-(omega-aminoalkyl)glycolic acid} for the delivery of a bioactive agent via tissue and cellular uptake
|
US6517869B1
(en)
|
1997-12-12 |
2003-02-11 |
Expression Genetics, Inc. |
Positively charged poly(alpha-(omega-aminoalkyl)lycolic acid) for the delivery of a bioactive agent via tissue and cellular uptake
|
JP2002500010A
(ja)
|
1997-12-23 |
2002-01-08 |
カイロン コーポレイション |
ヒト遺伝子および遺伝子発現産物i
|
US6383811B2
(en)
|
1997-12-30 |
2002-05-07 |
Mirus Corporation |
Polyampholytes for delivering polyions to a cell
|
CA2317549C
(en)
|
1998-01-05 |
2006-04-11 |
University Of Washington |
Composition for enhancing transport through lipid-containing membranes, and uses thereof
|
EP1045714A1
(en)
|
1998-01-08 |
2000-10-25 |
Sontra Medical, L.P. |
Sonophoretic enhanced transdermal transport
|
IT1298087B1
(it)
|
1998-01-08 |
1999-12-20 |
Fiderm S R L |
Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
|
US8287483B2
(en)
|
1998-01-08 |
2012-10-16 |
Echo Therapeutics, Inc. |
Method and apparatus for enhancement of transdermal transport
|
US6365346B1
(en)
|
1998-02-18 |
2002-04-02 |
Dade Behring Inc. |
Quantitative determination of nucleic acid amplification products
|
US5955310A
(en)
|
1998-02-26 |
1999-09-21 |
Novo Nordisk Biotech, Inc. |
Methods for producing a polypeptide in a bacillus cell
|
US6432925B1
(en)
|
1998-04-16 |
2002-08-13 |
John Wayne Cancer Institute |
RNA cancer vaccine and methods for its use
|
US6429301B1
(en)
|
1998-04-17 |
2002-08-06 |
Whitehead Institute For Biomedical Research |
Use of a ribozyme to join nucleic acids and peptides
|
GB9808327D0
(en)
|
1998-04-20 |
1998-06-17 |
Chiron Spa |
Antidiotypic compounds
|
EP2116600B1
(en)
|
1998-04-23 |
2013-09-18 |
Takara Bio Inc. |
Method for synthesizing DNA
|
US6395253B2
(en)
|
1998-04-23 |
2002-05-28 |
The Regents Of The University Of Michigan |
Microspheres containing condensed polyanionic bioactive agents and methods for their production
|
US20020064517A1
(en)
|
1998-04-30 |
2002-05-30 |
Stewart A. Cederholm-Williams |
Fibrin sealant as a transfection/transformation vehicle for gene therapy
|
US20090208418A1
(en)
|
2005-04-29 |
2009-08-20 |
Innexus Biotechnology Internaltional Ltd. |
Superantibody synthesis and use in detection, prevention and treatment of disease
|
IL139761A0
(en)
|
1998-05-20 |
2002-02-10 |
Expression Genetics Inc |
A hepatocyte targeting polyethylene glyco-grafted poly-l-lysine polymeric gene carrier
|
US6503231B1
(en)
|
1998-06-10 |
2003-01-07 |
Georgia Tech Research Corporation |
Microneedle device for transport of molecules across tissue
|
US7091192B1
(en)
|
1998-07-01 |
2006-08-15 |
California Institute Of Technology |
Linear cyclodextrin copolymers
|
CA2337680A1
(en)
|
1998-07-13 |
2000-01-20 |
Expression Genetics, Inc. |
Polyester analogue of poly-l-lysine as a soluble, biodegradable gene delivery carrier
|
JP2003505114A
(ja)
|
1998-07-13 |
2003-02-12 |
ジェネトロニクス、インコーポレーテッド |
パルス電場による皮膚および筋肉を標的とした遺伝子治療
|
US6222030B1
(en)
|
1998-08-03 |
2001-04-24 |
Agilent Technologies, Inc. |
Solid phase synthesis of oligonucleotides using carbonate protecting groups and alpha-effect nucleophile deprotection
|
EP1946775A3
(en)
|
1998-08-11 |
2008-08-06 |
Biogen Idec Inc. |
Combination therapies for B-cell lymphomas comprising administration of anti-CD20 antibody
|
GB9817662D0
(en)
|
1998-08-13 |
1998-10-07 |
Crocker Peter J |
Substance delivery
|
US20090148906A1
(en)
|
1998-09-29 |
2009-06-11 |
Shire Human Genetic Therapies, Inc. A Delaware Corporation |
Optimized messenger rna
|
US6924365B1
(en)
|
1998-09-29 |
2005-08-02 |
Transkaryotic Therapies, Inc. |
Optimized messenger RNA
|
AU772881B2
(en)
|
1998-11-03 |
2004-05-13 |
Yale University |
Multidomain polynucleotide molecular sensors
|
MXPA01004649A
(es)
|
1998-11-09 |
2002-05-06 |
Idec Pharma Corp |
Tratamiento con anticuerpo quimerico anti-cd20 para pacientes que reciben transplantes de medula osea o celulas madre de sangre periferica.
|
EP1949911A3
(en)
|
1998-11-09 |
2008-08-06 |
Biogen Idec, Inc. |
Treatment of chronique lymphocytic leukemia using chimeric anti-CD20 antibody.
|
AU2023400A
(en)
|
1998-11-12 |
2000-05-29 |
Children's Medical Center Corporation |
Compositions and methods for inhibiting angiogenesis using trna and fragments thereof
|
US6210931B1
(en)
|
1998-11-30 |
2001-04-03 |
The United States Of America As Represented By The Secretary Of Agriculture |
Ribozyme-mediated synthesis of circular RNA
|
US20040171980A1
(en)
|
1998-12-18 |
2004-09-02 |
Sontra Medical, Inc. |
Method and apparatus for enhancement of transdermal transport
|
US6444790B1
(en)
|
1998-12-23 |
2002-09-03 |
Human Genome Sciences, Inc. |
Peptidoglycan recognition proteins
|
WO2000050586A2
(en)
|
1999-02-22 |
2000-08-31 |
European Molecular Biology Laboratory |
In vitro translation system
|
US6255476B1
(en)
|
1999-02-22 |
2001-07-03 |
Pe Corporation (Ny) |
Methods and compositions for synthesis of labelled oligonucleotides and analogs on solid-supports
|
US7629311B2
(en)
|
1999-02-24 |
2009-12-08 |
Edward Lewis Tobinick |
Methods to facilitate transmission of large molecules across the blood-brain, blood-eye, and blood-nerve barriers
|
AU2875700A
(en)
|
1999-02-26 |
2000-09-14 |
Chiron Corporation |
Microemulsions with adsorbed macromoelecules and microparticles
|
WO2000029561A2
(en)
|
1999-03-29 |
2000-05-25 |
Statens Serum Institut |
Nucleotide construct with optimised codons for an hiv genetic vaccine based on a primary, early hiv isolate and synthetic envelope
|
EP1177231B1
(en)
|
1999-04-09 |
2009-08-19 |
Invitrogen Dynal AS |
Process for the preparation of monodisperse polymer particles
|
MXPA01011279A
(es)
|
1999-05-07 |
2002-07-02 |
Genentech Inc |
Tratamiento de enfermedades autoinmunes con antagonistas que se unene a los marcadores de superficie, de celulas b.
|
US8663692B1
(en)
|
1999-05-07 |
2014-03-04 |
Pharmasol Gmbh |
Lipid particles on the basis of mixtures of liquid and solid lipids and method for producing same
|
US6346382B1
(en)
|
1999-06-01 |
2002-02-12 |
Vanderbilt University |
Human carbamyl phosphate synthetase I polymorphism and diagnostic methods related thereto
|
AU4332399A
(en)
|
1999-06-04 |
2000-12-28 |
Cheng-Ming Chuong |
Rna polymerase chain reaction
|
US6611707B1
(en)
|
1999-06-04 |
2003-08-26 |
Georgia Tech Research Corporation |
Microneedle drug delivery device
|
US6743211B1
(en)
|
1999-11-23 |
2004-06-01 |
Georgia Tech Research Corporation |
Devices and methods for enhanced microneedle penetration of biological barriers
|
US6303573B1
(en)
|
1999-06-07 |
2001-10-16 |
The Burnham Institute |
Heart homing peptides and methods of using same
|
NZ515957A
(en)
|
1999-06-08 |
2003-08-29 |
Aventis Pasteur |
Immunostimulant oligonucleotide
|
AU782160B2
(en)
|
1999-06-09 |
2005-07-07 |
Immunomedics Inc. |
Immunotherapy of autoimmune disorders using antibodies which target B-cells
|
US6949245B1
(en)
|
1999-06-25 |
2005-09-27 |
Genentech, Inc. |
Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
|
IL147179A0
(en)
|
1999-06-30 |
2002-08-14 |
Advanced Cell Tech Inc |
Cytoplasmic transfer to de-differentiate recipient cells
|
US6514948B1
(en)
|
1999-07-02 |
2003-02-04 |
The Regents Of The University Of California |
Method for enhancing an immune response
|
BR0012325A
(pt)
|
1999-07-09 |
2002-05-21 |
American Home Prod |
Métodos e composições para prevenção da formação de rna anormal durante a transcrição de uma sequência de plasmìdeo
|
US8557244B1
(en)
|
1999-08-11 |
2013-10-15 |
Biogen Idec Inc. |
Treatment of aggressive non-Hodgkins lymphoma with anti-CD20 antibody
|
ES2282133T3
(es)
|
1999-08-24 |
2007-10-16 |
Medarex, Inc. |
Anticuerpos frente a la ctla-4 humano y sus usos.
|
US20050112141A1
(en)
|
2000-08-30 |
2005-05-26 |
Terman David S. |
Compositions and methods for treatment of neoplastic disease
|
US20040106567A1
(en)
|
1999-09-07 |
2004-06-03 |
Hagstrom James E. |
Intravascular delivery of non-viral nucleic acid
|
ATE289630T1
(de)
|
1999-09-09 |
2005-03-15 |
Curevac Gmbh |
Transfer von mrnas unter verwendung von polykationischen verbindungen
|
WO2001021810A1
(en)
|
1999-09-17 |
2001-03-29 |
Aventis Pasteur Limited |
Chlamydia antigens and corresponding dna fragments and uses thereof
|
US6623457B1
(en)
|
1999-09-22 |
2003-09-23 |
Becton, Dickinson And Company |
Method and apparatus for the transdermal administration of a substance
|
WO2002064799A2
(en)
|
1999-09-28 |
2002-08-22 |
Transkaryotic Therapies, Inc. |
Optimized messenger rna
|
WO2001025488A2
(en)
|
1999-10-06 |
2001-04-12 |
Quark Biotech, Inc. |
Method for enrichment of natural antisense messenger rna
|
US7060291B1
(en)
|
1999-11-24 |
2006-06-13 |
Transave, Inc. |
Modular targeted liposomal delivery system
|
US6613026B1
(en)
|
1999-12-08 |
2003-09-02 |
Scimed Life Systems, Inc. |
Lateral needle-less injection apparatus and method
|
US6277974B1
(en)
|
1999-12-14 |
2001-08-21 |
Cogent Neuroscience, Inc. |
Compositions and methods for diagnosing and treating conditions, disorders, or diseases involving cell death
|
US6245929B1
(en)
|
1999-12-20 |
2001-06-12 |
General Electric Company |
Catalyst composition and method for producing diaryl carbonates, using bisphosphines
|
JP4758583B2
(ja)
|
1999-12-22 |
2011-08-31 |
バセル テクノロジー カンパニー ビー.ブイ. |
芳香族シラン化合物を含むα−オレフィン重合触媒系
|
AU2764801A
(en)
|
2000-01-07 |
2001-07-24 |
University Of Washington |
Enhanced transport of agents using membrane disruptive agents
|
EP1276901A2
(en)
|
2000-01-13 |
2003-01-22 |
Amsterdam Support Diagnostics B.V. |
A universal nucleic acid amplification system for nucleic acids in a sample
|
US6552006B2
(en)
|
2000-01-31 |
2003-04-22 |
The Regents Of The University Of California |
Immunomodulatory polynucleotides in treatment of an infection by an intracellular pathogen
|
CA2395811A1
(en)
|
2000-01-31 |
2001-08-02 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
WO2001062827A2
(en)
|
2000-02-22 |
2001-08-30 |
Shearwater Corporation |
N-maleimidyl polymer derivatives
|
PL218883B1
(pl)
|
2000-02-24 |
2015-02-27 |
Lilly Co Eli |
Kompozycja farmaceutyczna zawierająca przeciwciało do zastosowania w leczeniu klinicznej lub przedklinicznej choroby Alzheimera
|
AU2001245427A1
(en)
|
2000-03-03 |
2001-09-17 |
Valentis, Inc. |
Nucleic acid formulations for gene delivery and methods of use
|
CN1981868A
(zh)
|
2000-03-31 |
2007-06-20 |
拜奥根Idec公司 |
抗细胞因子抗体或拮抗剂与抗-cd20在b细胞淋巴瘤治疗中的联合应用
|
AU2001249727A1
(en)
|
2000-03-31 |
2001-10-15 |
Genentech, Inc. |
Compositions and methods for detecting and quantifying gene expression
|
US6565572B2
(en)
|
2000-04-10 |
2003-05-20 |
Sdgi Holdings, Inc. |
Fenestrated surgical screw and method
|
AU2001266557A1
(en)
|
2000-04-12 |
2001-10-23 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
US6368801B1
(en)
|
2000-04-12 |
2002-04-09 |
Molecular Staging, Inc. |
Detection and amplification of RNA using target-mediated ligation of DNA by RNA ligase
|
US20010046496A1
(en)
|
2000-04-14 |
2001-11-29 |
Brettman Lee R. |
Method of administering an antibody
|
US6375972B1
(en)
|
2000-04-26 |
2002-04-23 |
Control Delivery Systems, Inc. |
Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
|
US20040229271A1
(en)
|
2000-05-19 |
2004-11-18 |
Williams Richard B. |
Compositions and methods for the identification and selection of nucleic acids and polypeptides
|
WO2001092523A2
(en)
|
2000-05-30 |
2001-12-06 |
Curagen Corporation |
Human polynucleotides and polypeptides encoded thereby
|
CA2412026A1
(en)
|
2000-06-07 |
2001-12-13 |
Biosynexus Incorporated |
Immunostimulatory rna/dna hybrid molecules
|
DE60124098T2
(de)
|
2000-06-23 |
2007-04-05 |
Wyeth Holdings Corp. |
Modifiziertes Morbillivirus V Proteine
|
EP1297005B1
(en)
|
2000-07-03 |
2009-08-26 |
Novartis Vaccines and Diagnostics S.r.l. |
Immunisation against chlamydia pneumoniae
|
US6440096B1
(en)
|
2000-07-14 |
2002-08-27 |
Becton, Dickinson And Co. |
Microdevice and method of manufacturing a microdevice
|
IL154009A0
(en)
|
2000-07-21 |
2003-07-31 |
Glaxo Group Ltd |
Codon-optimized papilloma virus sequences
|
US6902734B2
(en)
|
2000-08-07 |
2005-06-07 |
Centocor, Inc. |
Anti-IL-12 antibodies and compositions thereof
|
US6696038B1
(en)
|
2000-09-14 |
2004-02-24 |
Expression Genetics, Inc. |
Cationic lipopolymer as biocompatible gene delivery agent
|
US20040142474A1
(en)
|
2000-09-14 |
2004-07-22 |
Expression Genetics, Inc. |
Novel cationic lipopolymer as a biocompatible gene delivery agent
|
AU2001290078A1
(en)
|
2000-09-20 |
2002-04-02 |
Ruggero Della Bitta |
Stem cell therapy
|
AU2002211490A1
(en)
|
2000-10-04 |
2002-04-15 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods of using capsid protein from flaviviruses and pestiviruses
|
US6998115B2
(en)
|
2000-10-10 |
2006-02-14 |
Massachusetts Institute Of Technology |
Biodegradable poly(β-amino esters) and uses thereof
|
US7202226B2
(en)
|
2000-10-23 |
2007-04-10 |
Detroit R & D |
Augmentation of wound healing by elF-4E mRNA and EGF mRNA
|
US20030077604A1
(en)
|
2000-10-27 |
2003-04-24 |
Yongming Sun |
Compositions and methods relating to breast specific genes and proteins
|
US20020132788A1
(en)
|
2000-11-06 |
2002-09-19 |
David Lewis |
Inhibition of gene expression by delivery of small interfering RNA to post-embryonic animal cells in vivo
|
WO2002040545A2
(en)
|
2000-11-17 |
2002-05-23 |
The Government Of The United States, As Represented By The Secretary Of The Department Of Health And Human Services |
Reduction of the nonspecific animal toxicity of immunotoxins by mutating the framework regions of the fv to lower the isoelectric point
|
JP2004535765A
(ja)
|
2000-12-07 |
2004-12-02 |
カイロン コーポレイション |
前立腺癌においてアップレギュレートされた内因性レトロウイルス
|
US20020130430A1
(en)
|
2000-12-29 |
2002-09-19 |
Castor Trevor Percival |
Methods for making polymer microspheres/nanospheres and encapsulating therapeutic proteins and other products
|
US7708915B2
(en)
|
2004-05-06 |
2010-05-04 |
Castor Trevor P |
Polymer microspheres/nanospheres and encapsulating therapeutic proteins therein
|
EP1224943A1
(en)
|
2001-01-19 |
2002-07-24 |
Crucell Holland B.V. |
Fibronectin as a tumor marker detected by phage antibodies
|
PL213926B1
(pl)
|
2001-01-19 |
2013-05-31 |
Vironovative Bv |
Wyizolowany ssaczy metapneumowirus o ujemnej pojedynczej nici RNA (MPV), kompozycja immunogenna, wyizolowane kwasy nukleinowe, sposoby wykrywania ssaczego metapneumowirusa, wektor, komórka gospodarza, wyizolowane bialko, przeciwcialo, sposób wirologicznego diagnozowania infekcji MPV, sposób serologicznego diagnozowania infekcji MPV, kompozycja farmaceutyczna, zestaw diagnostyczny oraz zastosowanie kompozycji farmaceutycznej
|
US20040110191A1
(en)
|
2001-01-31 |
2004-06-10 |
Winkler Matthew M. |
Comparative analysis of nucleic acids using population tagging
|
US20030186237A1
(en)
|
2001-02-14 |
2003-10-02 |
Baylor College Of Medicine |
Methods and compositions of amplifying RNA
|
US6652886B2
(en)
|
2001-02-16 |
2003-11-25 |
Expression Genetics |
Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents
|
DE10109897A1
(de)
|
2001-02-21 |
2002-11-07 |
Novosom Ag |
Fakultativ kationische Liposomen und Verwendung dieser
|
US7232425B2
(en)
|
2001-03-02 |
2007-06-19 |
Sorenson Development, Inc. |
Apparatus and method for specific interstitial or subcutaneous diffusion and dispersion of medication
|
ATE404679T1
(de)
|
2001-03-09 |
2008-08-15 |
Gene Stream Pty Ltd |
Neue expressionsvektoren
|
JP2002262882A
(ja)
|
2001-03-12 |
2002-09-17 |
Nisshinbo Ind Inc |
Rnaの増幅法
|
FR2822164B1
(fr)
|
2001-03-19 |
2004-06-18 |
Centre Nat Rech Scient |
Polypeptides derives des arn polymerases, et leurs utilisations
|
US6520949B2
(en)
|
2001-04-02 |
2003-02-18 |
Martin St. Germain |
Method and apparatus for administering fluid to animals subcutaneously
|
DE10119005A1
(de)
|
2001-04-18 |
2002-10-24 |
Roche Diagnostics Gmbh |
Verfahren zur Proteinexpression ausgehend von stabilisierter linearer kurzer DNA in zellfreien in vitro-Transkription/Translations-Systemen mit Exonuklease-haltigen Lysaten oder in einem zellulären System enthaltend Exonukleasen
|
US20030171253A1
(en)
|
2001-04-19 |
2003-09-11 |
Averil Ma |
Methods and compositions relating to modulation of A20
|
MXPA03009622A
(es)
|
2001-04-23 |
2005-03-07 |
Amaxa Gmbh |
Solucion amortiguadora para electroporacion y metodo que comprende el uso de la misma.
|
US7560424B2
(en)
|
2001-04-30 |
2009-07-14 |
Zystor Therapeutics, Inc. |
Targeted therapeutic proteins
|
US6777187B2
(en)
|
2001-05-02 |
2004-08-17 |
Rubicon Genomics, Inc. |
Genome walking by selective amplification of nick-translate DNA library and amplification from complex mixtures of templates
|
US6527216B2
(en)
|
2001-05-08 |
2003-03-04 |
Magnatech International Llp |
Electronic length control wire pay-off system and method
|
US20050137155A1
(en)
|
2001-05-18 |
2005-06-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated treatment of Parkinson disease using short interfering nucleic acid (siNA)
|
US8137911B2
(en)
|
2001-05-22 |
2012-03-20 |
Cellscript, Inc. |
Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
|
RU2294192C2
(ru)
|
2001-05-30 |
2007-02-27 |
Дзе Скриппс Рисерч Инститьют |
Система доставки нуклеиновых кислот
|
EP2305699B1
(de)
|
2001-06-05 |
2014-08-13 |
CureVac GmbH |
Stabilisierte mRNA mit erhöhtem G/C-Gehalt und optimierter Codon Usage für die Impfung gegen Schlafkrankheit, Leishmaniose und Toxoplasmose
|
US20040175787A1
(en)
|
2001-06-18 |
2004-09-09 |
Klemens Kaupmann |
Novel g-protein coupled receptors and dna sequences thereof
|
US7547551B2
(en)
|
2001-06-21 |
2009-06-16 |
University Of Antwerp. |
Transfection of eukaryontic cells with linear polynucleotides by electroporation
|
US7785610B2
(en)
|
2001-06-21 |
2010-08-31 |
Dynavax Technologies Corporation |
Chimeric immunomodulatory compounds and methods of using the same—III
|
US20040175789A1
(en)
|
2001-06-26 |
2004-09-09 |
Umesh Bhatia |
G protein coupled receptors and dna sequences thereof
|
SE0102327D0
(sv)
|
2001-06-28 |
2001-06-28 |
Active Biotech Ab |
A novel engineered superantigen for human therapy
|
WO2003029401A2
(en)
|
2001-07-13 |
2003-04-10 |
Advanced Research And Technology Institute |
Peptidoglycan recognition protein encoding nucleic acids and methods of use thereof
|
US6586524B2
(en)
|
2001-07-19 |
2003-07-01 |
Expression Genetics, Inc. |
Cellular targeting poly(ethylene glycol)-grafted polymeric gene carrier
|
US7169750B2
(en)
|
2001-07-31 |
2007-01-30 |
Anormed, Inc. |
Methods to mobilize progenitor/stem cells
|
JP2004536614A
(ja)
|
2001-08-01 |
2004-12-09 |
ユニバーシティ オブ ユタ |
Pde3環状ヌクレオチド・ホスホジエステラーゼのアイソフォーム選択的な阻害剤および活性化剤
|
EP1423519A2
(en)
|
2001-08-27 |
2004-06-02 |
Novartis AG |
G-protein coupled receptor and dna sequences thereof
|
US20040142325A1
(en)
|
2001-09-14 |
2004-07-22 |
Liat Mintz |
Methods and systems for annotating biomolecular sequences
|
AR045702A1
(es)
|
2001-10-03 |
2005-11-09 |
Chiron Corp |
Composiciones de adyuvantes.
|
DE10148886A1
(de)
|
2001-10-04 |
2003-04-30 |
Avontec Gmbh |
Inhibition von STAT-1
|
US7276489B2
(en)
|
2002-10-24 |
2007-10-02 |
Idera Pharmaceuticals, Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends
|
EP1452593B1
(en)
|
2001-11-14 |
2009-04-08 |
Toyo Boseki Kabushiki Kaisha |
Dna synthesis promoters, dna polymerase-associated factors and utilization thereof
|
WO2003044482A2
(en)
|
2001-11-16 |
2003-05-30 |
The University Of Tennessee Research Corporation |
Recombinant antibody fusion proteins and methods for detection of apoptotic cells
|
EP1454145A2
(en)
|
2001-11-29 |
2004-09-08 |
Novartis AG |
Method for the assessment and prognosis of sarcoidosis
|
CA2409775C
(en)
|
2001-12-03 |
2010-07-13 |
F. Hoffmann-La Roche Ag |
Reversibly modified thermostable enzymes for dna synthesis and amplification in vitro
|
US20060275747A1
(en)
|
2001-12-07 |
2006-12-07 |
Hardy Stephen F |
Endogenous retrovirus up-regulated in prostate cancer
|
CA2469049A1
(en)
|
2001-12-07 |
2003-06-19 |
Chiron Corporation |
Endogenous retrovirus polypeptides linked to oncogenic transformation
|
ATE458003T1
(de)
|
2001-12-07 |
2010-03-15 |
Novartis Vaccines & Diagnostic |
Bei prostatakrebs hochreguliertes endogenes retrovirus
|
US20050107589A1
(en)
|
2001-12-17 |
2005-05-19 |
Gung-Wei Chirn |
Novel g-protein coupled receptors and dna sequences thereof
|
DE10162480A1
(de)
|
2001-12-19 |
2003-08-07 |
Ingmar Hoerr |
Die Applikation von mRNA für den Einsatz als Therapeutikum gegen Tumorerkrankungen
|
PL211494B1
(pl)
|
2001-12-21 |
2012-05-31 |
Alcon |
Zastosowanie syntetycznych, nieorganicznych nanocząstek jako nośników dla leków i kompozycja farmaceutyczna do oczu lub uszu
|
AU2003235707A1
(en)
|
2002-01-18 |
2003-07-30 |
Curevac Gmbh |
Immunogenic preparations and vaccines on the basis of mrna
|
AU2003203079B9
(en)
|
2002-02-04 |
2009-01-15 |
Oncothyreon Inc. |
Immunostimulatory, covalently lipidated oligonucleotides
|
JP4460302B2
(ja)
|
2002-02-05 |
2010-05-12 |
ジェネンテック インコーポレイテッド |
タンパク質精製法
|
FR2835749B1
(fr)
|
2002-02-08 |
2006-04-14 |
Inst Nat Sante Rech Med |
Composition pharmaceutique ameliorant le transfert de gene in vivo
|
DE10207178A1
(de)
|
2002-02-19 |
2003-09-04 |
Novosom Ag |
Komponenten für die Herstellung amphoterer Liposomen
|
AR038568A1
(es)
|
2002-02-20 |
2005-01-19 |
Hoffmann La Roche |
Anticuerpos anti-a beta y su uso
|
US7354742B2
(en)
|
2002-02-22 |
2008-04-08 |
Ortho-Mcneil Pharmaceutical, Inc. |
Method for generating amplified RNA
|
NZ535690A
(en)
|
2002-02-26 |
2009-04-30 |
Maxygen Inc |
Novel flavivirus antigens
|
DK1916001T3
(da)
|
2002-03-04 |
2011-07-18 |
Imclone Llc |
KDR-specifikke humane antistoffer og anvendelser deraf
|
JP4679822B2
(ja)
|
2002-03-13 |
2011-05-11 |
ノバルティス アーゲー |
医薬微粒子
|
US7074596B2
(en)
|
2002-03-25 |
2006-07-11 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Synthesis and use of anti-reverse mRNA cap analogues
|
EP1499187B1
(en)
|
2002-04-04 |
2015-06-17 |
Zoetis Belgium S.A. |
Immunostimulatory g,u-containing oligoribonucleotides
|
AU2003226820A1
(en)
|
2002-04-17 |
2003-10-27 |
Novartis Ag |
Method for the identification of inhibitors of the binding of are-containing mrn a and an hur protein
|
GB0209539D0
(en)
|
2002-04-26 |
2002-06-05 |
Avecia Ltd |
Monomer Polymer and process
|
EP1361277A1
(en)
|
2002-04-30 |
2003-11-12 |
Centre National De La Recherche Scientifique (Cnrs) |
Optimization of transgene expression in mammalian cells
|
PL224150B1
(pl)
|
2002-05-02 |
2016-11-30 |
Wyeth Corp |
Kompozycja zawierająca koniugat leku obejmujący pochodne kalicheamycyny i przeciwciało, oraz kompozycja farmaceutyczna ją zawierająca
|
US7374930B2
(en)
|
2002-05-21 |
2008-05-20 |
Expression Genetics, Inc. |
GLP-1 gene delivery for the treatment of type 2 diabetes
|
US20040018525A1
(en)
|
2002-05-21 |
2004-01-29 |
Bayer Aktiengesellschaft |
Methods and compositions for the prediction, diagnosis, prognosis, prevention and treatment of malignant neoplasma
|
DE10224200C1
(de)
|
2002-05-31 |
2003-08-21 |
Artus Ges Fuer Molekularbiolog |
Vermehrung von Ribonukleinsäuren
|
AU2003237367A1
(en)
|
2002-06-03 |
2003-12-19 |
Chiron Corporation |
Use of nrg4, or inhibitors thereof, in the treatment of colon and pancreatic cancer
|
DE60334618D1
(de)
|
2002-06-28 |
2010-12-02 |
Protiva Biotherapeutics Inc |
Verfahren und vorrichtung zur herstellung von liposomen
|
US20040122216A1
(en)
|
2002-07-01 |
2004-06-24 |
Jacob Nielsen |
Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs
|
DE10229872A1
(de)
|
2002-07-03 |
2004-01-29 |
Curevac Gmbh |
Immunstimulation durch chemisch modifizierte RNA
|
GB0215509D0
(en)
|
2002-07-04 |
2002-08-14 |
Novartis Ag |
Marker genes
|
DE60336736D1
(de)
|
2002-07-16 |
2011-05-26 |
VGX Pharmaceuticals LLC |
Codon-optimierte synthetische plasmide
|
WO2004010106A2
(en)
|
2002-07-24 |
2004-01-29 |
Ptc Therapeutics, Inc. |
METHODS FOR IDENTIFYING SMALL MOLEDULES THAT MODULATE PREMATURE TRANSLATION TERMINATION AND NONSENSE MEDIATED mRNA DECAY
|
EP1393745A1
(en)
|
2002-07-29 |
2004-03-03 |
Hybridon, Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5'ends
|
US6653468B1
(en)
|
2002-07-31 |
2003-11-25 |
Isis Pharmaceuticals, Inc. |
Universal support media for synthesis of oligomeric compounds
|
EP1386925A1
(en)
|
2002-07-31 |
2004-02-04 |
Girindus AG |
Method for preparing oligonucleotides
|
EP1873180B1
(en)
|
2002-08-14 |
2014-05-07 |
Novartis AG |
Ophthalmic device made from a radiation-curable prepolymer
|
PT1534340E
(pt)
|
2002-09-06 |
2012-03-13 |
Cerulean Pharma Inc |
Polímeros à base de ciclodextrina para a administração de medicamentos ligados por ligação covalente
|
WO2004022629A2
(en)
|
2002-09-09 |
2004-03-18 |
Nektar Therapeutics Al, Corporation |
Method for preparing water-soluble polymer derivatives bearing a terminal carboxylic acid
|
US7534872B2
(en)
|
2002-09-27 |
2009-05-19 |
Syngen, Inc. |
Compositions and methods for the use of FMOC derivatives in DNA/RNA synthesis
|
CA2502552C
(en)
|
2002-10-17 |
2019-02-12 |
Genmab A/S |
Human monoclonal antibodies against cd20
|
ATE492636T1
(de)
|
2002-10-22 |
2011-01-15 |
Eisai R&D Man Co Ltd |
Spezifisch in postmitotischen dopamin- produzierenden neuronalen vorläuferzellen exprimiertes gen
|
WO2004048594A2
(en)
|
2002-11-21 |
2004-06-10 |
Epicentre Technologies |
Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
|
US7491234B2
(en)
|
2002-12-03 |
2009-02-17 |
Boston Scientific Scimed, Inc. |
Medical devices for delivery of therapeutic agents
|
EP1944320A1
(en)
|
2002-12-16 |
2008-07-16 |
Genentech, Inc. |
Immunoglobulin variants and uses thereof
|
EP1625140A4
(en)
|
2002-12-23 |
2008-06-18 |
Dynavax Tech Corp |
BRANCHED IMMUNOMODULAR COMPOUNDS AND METHOD OF USE THEREOF
|
US7169892B2
(en)
|
2003-01-10 |
2007-01-30 |
Astellas Pharma Inc. |
Lipid-peptide-polymer conjugates for long blood circulation and tumor specific drug delivery systems
|
WO2004067728A2
(en)
|
2003-01-17 |
2004-08-12 |
Ptc Therapeutics |
Methods and systems for the identification of rna regulatory sequences and compounds that modulate their function
|
US8426194B2
(en)
|
2003-01-21 |
2013-04-23 |
Ptc Therapeutics, Inc. |
Methods and agents for screening for compounds capable of modulating VEGF expression
|
US9068234B2
(en)
|
2003-01-21 |
2015-06-30 |
Ptc Therapeutics, Inc. |
Methods and agents for screening for compounds capable of modulating gene expression
|
CA2514184C
(en)
|
2003-01-21 |
2016-04-12 |
Ptc Therapeutics, Inc. |
Methods for identifying compounds that modulate untranslated region-dependent gene expression and methods of using same
|
US20040147027A1
(en)
|
2003-01-28 |
2004-07-29 |
Troy Carol M. |
Complex for facilitating delivery of dsRNA into a cell and uses thereof
|
CN103040732B
(zh)
|
2003-02-10 |
2015-04-01 |
伊兰药品公司 |
免疫球蛋白制剂及其制备方法
|
US20040167090A1
(en)
|
2003-02-21 |
2004-08-26 |
Monahan Sean D. |
Covalent modification of RNA for in vitro and in vivo delivery
|
CA2450289A1
(en)
|
2003-03-20 |
2005-05-19 |
Imclone Systems Incorporated |
Method of producing an antibody to epidermal growth factor receptor
|
US7320961B2
(en)
|
2003-03-24 |
2008-01-22 |
Abbott Laboratories |
Method for treating a disease, disorder or adverse effect caused by an elevated serum concentration of an UGT1A1 substrate
|
US7704712B2
(en)
|
2003-03-25 |
2010-04-27 |
Stratagene California |
DNA polymerase fusions and uses thereof
|
WO2004092329A2
(en)
|
2003-04-08 |
2004-10-28 |
Galenica Pharmaceuticals, Inc. |
Semi-synthetic saponin analogs with carrier and immune stimulatory activities for dna and rna vaccines
|
MXPA05010778A
(es)
|
2003-04-09 |
2005-12-12 |
Genentech Inc |
Terapia para enfermedad autoinmune en un paciente con una respuesta inadecuada a un inhibidor tnf-alfa.
|
KR101180896B1
(ko)
|
2003-05-05 |
2012-09-07 |
벤-구리온 유니버시티 오브 더 네게브 리서치 앤드 디벨럽먼트 어쏘러티 |
주사용 가교결합된 폴리머 제제 및 그의 용도
|
US7348004B2
(en)
|
2003-05-06 |
2008-03-25 |
Syntonix Pharmaceuticals, Inc. |
Immunoglobulin chimeric monomer-dimer hybrids
|
ES2558102T3
(es)
|
2003-05-06 |
2016-02-02 |
Biogen Hemophilia Inc. |
Proteínas quiméricas del factor de coagulación para el tratamiento de un trastorno hemostático
|
TWI353991B
(en)
|
2003-05-06 |
2011-12-11 |
Syntonix Pharmaceuticals Inc |
Immunoglobulin chimeric monomer-dimer hybrids
|
US9567591B2
(en)
|
2003-05-15 |
2017-02-14 |
Mello Biotechnology, Inc. |
Generation of human embryonic stem-like cells using intronic RNA
|
GB0313132D0
(en)
|
2003-06-06 |
2003-07-09 |
Ich Productions Ltd |
Peptide ligands
|
WO2005009346A2
(en)
|
2003-06-24 |
2005-02-03 |
Mirus Corporation |
Inhibition of gene function by delivery of polynucleotide-based gene expression inhibitors to mammalian cells in vivo
|
GB0316089D0
(en)
|
2003-07-09 |
2003-08-13 |
Xo Bioscience Ltd |
Differentiation method
|
US8592197B2
(en)
|
2003-07-11 |
2013-11-26 |
Novavax, Inc. |
Functional influenza virus-like particles (VLPs)
|
US7575572B2
(en)
|
2003-07-15 |
2009-08-18 |
Spinal Generations, Llc |
Method and device for delivering medicine to bone
|
US20050013870A1
(en)
|
2003-07-17 |
2005-01-20 |
Toby Freyman |
Decellularized extracellular matrix of conditioned body tissues and uses thereof
|
RS53476B
(en)
|
2003-07-18 |
2014-12-31 |
Amgen Fremont Inc. |
Hepatocyte Growth Factor Binders
|
DE10335833A1
(de)
|
2003-08-05 |
2005-03-03 |
Curevac Gmbh |
Transfektion von Blutzellen mit mRNA zur Immunstimulation und Gentherapie
|
US8668926B1
(en)
|
2003-09-15 |
2014-03-11 |
Shaker A. Mousa |
Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof
|
US7135010B2
(en)
|
2003-09-30 |
2006-11-14 |
Damage Control Surgical Technologies, Inc. |
Method and apparatus for rapid deployment chest drainage
|
AU2004283235B2
(en)
|
2003-10-06 |
2007-08-02 |
Novartis Ag |
Use of genetic polymorphisms that associate with efficacy of treatment of inflammatory disease
|
DE10347710B4
(de)
|
2003-10-14 |
2006-03-30 |
Johannes-Gutenberg-Universität Mainz |
Rekombinante Impfstoffe und deren Verwendung
|
US20050130201A1
(en)
|
2003-10-14 |
2005-06-16 |
Dharmacon, Inc. |
Splint-assisted enzymatic synthesis of polyribounucleotides
|
HUE038955T2
(hu)
|
2003-11-05 |
2018-12-28 |
Roche Glycart Ag |
Antigén-kötõ molekulák fokozott Fc receptor-kötõ affinitással és effektor funkcióval
|
WO2005047536A2
(en)
|
2003-11-13 |
2005-05-26 |
Novartis Ag |
Detection of genomic amplification and deletion in cancer
|
US20070054278A1
(en)
|
2003-11-18 |
2007-03-08 |
Applera Corporation |
Polymorphisms in nucleic acid molecules encoding human enzyme proteins, methods of detection and uses thereof
|
US7699852B2
(en)
|
2003-11-19 |
2010-04-20 |
Zimmer Spine, Inc. |
Fenestrated bone tap and method
|
US20050153333A1
(en)
|
2003-12-02 |
2005-07-14 |
Sooknanan Roy R. |
Selective terminal tagging of nucleic acids
|
WO2005055945A2
(en)
|
2003-12-08 |
2005-06-23 |
Gel-Del Technologies, Inc. |
Mucoadhesive drug delivery devices and methods of making and using thereof
|
US7674884B2
(en)
|
2003-12-10 |
2010-03-09 |
Novimmune S.A. |
Neutralizing antibodies and methods of use thereof
|
WO2005062854A2
(en)
|
2003-12-19 |
2005-07-14 |
University Of Cincinnati |
Polyamides for nucleic acid delivery
|
AU2004308494B2
(en)
|
2003-12-23 |
2010-03-18 |
Genentech, Inc. |
Novel anti-IL 13 antibodies and uses thereof
|
WO2005072710A2
(en)
|
2004-01-28 |
2005-08-11 |
Johns Hopkins University |
Drugs and gene carrier particles that rapidly move through mucous barriers
|
ATE440949T1
(de)
|
2004-01-30 |
2009-09-15 |
Maxygen Holdings Ltd |
Gesteuertes überlesen von stopcodons
|
US7309487B2
(en)
|
2004-02-09 |
2007-12-18 |
George Inana |
Methods and compositions for detecting and treating retinal diseases
|
AU2005214331B2
(en)
|
2004-02-12 |
2011-09-15 |
Eisai, Inc. |
Monoclonal antibodies that specifically bind to folate receptor alpha
|
US20070265220A1
(en)
|
2004-03-15 |
2007-11-15 |
City Of Hope |
Methods and compositions for the specific inhibition of gene expression by double-stranded RNA
|
JPWO2005090405A1
(ja)
|
2004-03-24 |
2008-04-17 |
中外製薬株式会社 |
インターロイキン−6受容体に対するヒト型化抗体のサブタイプ
|
WO2005098433A2
(en)
|
2004-04-01 |
2005-10-20 |
Novartis Ag |
Diagnostic assays for alzheimer’s disease
|
EP1740946B1
(en)
|
2004-04-20 |
2013-11-06 |
Genmab A/S |
Human monoclonal antibodies against cd20
|
ES2246694B1
(es)
|
2004-04-29 |
2007-05-01 |
Instituto Cientifico Y Tecnologico De Navarra, S.A. |
Nanoparticulas pegiladas.
|
US20080119645A1
(en)
|
2004-05-05 |
2008-05-22 |
Isis Pharmaceuticals, Inc. |
Amidites and Methods of Rna Synthesis
|
PT1765294E
(pt)
|
2004-05-12 |
2008-12-30 |
Baxter Healthcare Sa |
Microesferas de ácido nucleico, sua produção e entrega
|
US8012747B2
(en)
|
2004-06-01 |
2011-09-06 |
San Diego State University Foundation |
Expression system
|
US7745651B2
(en)
|
2004-06-07 |
2010-06-29 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods of use
|
AU2005252273B2
(en)
|
2004-06-07 |
2011-04-28 |
Arbutus Biopharma Corporation |
Lipid encapsulated interfering RNA
|
CA2608862C
(en)
|
2004-06-11 |
2020-05-05 |
Trustees Of Tufts College |
Silk-based drug delivery system
|
WO2006046978A2
(en)
|
2004-06-28 |
2006-05-04 |
Argos Therapeutics, Inc. |
Cationic peptide-mediated transformation
|
MXPA06015234A
(es)
|
2004-06-30 |
2007-11-22 |
Nektar Therapeutics Al Corp |
Conjugados de fraccion polimero-factor ix.
|
DE102004035227A1
(de)
|
2004-07-21 |
2006-02-16 |
Curevac Gmbh |
mRNA-Gemisch zur Vakzinierung gegen Tumorerkrankungen
|
US7579451B2
(en)
|
2004-07-21 |
2009-08-25 |
Alnylam Pharmaceuticals, Inc. |
Oligonucleotides comprising a modified or non-natural nucleobase
|
US7603349B1
(en)
|
2004-07-29 |
2009-10-13 |
Yahoo! Inc. |
User interfaces for search systems using in-line contextual queries
|
GB0417487D0
(en)
|
2004-08-05 |
2004-09-08 |
Novartis Ag |
Organic compound
|
US7291208B2
(en)
|
2004-08-13 |
2007-11-06 |
Gore Enterprise Holdings, Inc. |
Grooved active and passive adsorbent filters
|
SE0402025D0
(sv)
|
2004-08-13 |
2004-08-13 |
Active Biotech Ab |
Treatment of hyperproliferative disease with superantigens in combination with another anticancer agent
|
CA2478458A1
(en)
|
2004-08-20 |
2006-02-20 |
Michael Panzara |
Treatment of pediatric multiple sclerosis
|
JP4965447B2
(ja)
|
2004-08-26 |
2012-07-04 |
エンジーンアイシー モレキュラー デリバリー ピーティーワイ リミテッド |
細菌由来のインタクトなミニセルを介した哺乳動物細胞への機能性核酸の送達
|
DE102004042546A1
(de)
|
2004-09-02 |
2006-03-09 |
Curevac Gmbh |
Kombinationstherapie zur Immunstimulation
|
US7501486B2
(en)
|
2004-09-07 |
2009-03-10 |
Burnham Institute For Medical Research |
Peptides that selectively home to heart vasculature and related conjugates and methods
|
US8663599B1
(en)
|
2004-10-05 |
2014-03-04 |
Gp Medical, Inc. |
Pharmaceutical composition of nanoparticles
|
WO2006041088A1
(ja)
|
2004-10-12 |
2006-04-20 |
Tissue Targeting Japan Inc. |
脳移行性骨髄前駆細胞
|
EP2363129A1
(en)
|
2004-10-13 |
2011-09-07 |
PTC Therapeutics, Inc. |
Pyrazole or triazole compounds and their use for the manufacture of a medicament for treating somatic mutation-related diseases
|
US8057821B2
(en)
|
2004-11-03 |
2011-11-15 |
Egen, Inc. |
Biodegradable cross-linked cationic multi-block copolymers for gene delivery and methods of making thereof
|
WO2006047842A2
(en)
|
2004-11-08 |
2006-05-11 |
K.U. Leuven Research And Development |
Modified nucleosides for rna interference
|
EP1817025A2
(en)
|
2004-11-23 |
2007-08-15 |
PTC Therapeutics, Inc. |
Tetrahydrocarbazoles as active agents for inhibiting vegf production by translational control
|
US7838657B2
(en)
*
|
2004-12-03 |
2010-11-23 |
University Of Massachusetts |
Spinal muscular atrophy (SMA) treatment via targeting of SMN2 splice site inhibitory sequences
|
US7964571B2
(en)
|
2004-12-09 |
2011-06-21 |
Egen, Inc. |
Combination of immuno gene therapy and chemotherapy for treatment of cancer and hyperproliferative diseases
|
ES2407979T3
(es)
|
2004-12-10 |
2013-06-17 |
Kala Pharmaceuticals, Inc. |
Copolímeros de bloques de poli(éter-anhídrido) funcionalizados
|
WO2006071903A2
(en)
|
2004-12-28 |
2006-07-06 |
Ptc Therapeutics, Inc. |
Cell based methods and systems for the identification of rna regulatory sequences and compounds that modulate their functions
|
US8535702B2
(en)
|
2005-02-01 |
2013-09-17 |
Boston Scientific Scimed, Inc. |
Medical devices having porous polymeric regions for controlled drug delivery and regulated biocompatibility
|
WO2006095259A2
(en)
|
2005-03-11 |
2006-09-14 |
Novartis Ag |
Biomarkers for cardiovascular side-effects induced by cox-2 inhibitory compounds
|
US8415325B2
(en)
|
2005-03-31 |
2013-04-09 |
University Of Delaware |
Cell-mediated delivery and targeted erosion of noncovalently crosslinked hydrogels
|
WO2006110599A2
(en)
|
2005-04-07 |
2006-10-19 |
Novartis Vaccines And Diagnostics Inc. |
Cacna1e in cancer diagnosis, detection and treatment
|
JP2008535853A
(ja)
|
2005-04-07 |
2008-09-04 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス インコーポレイテッド |
癌関連遺伝子
|
US8273339B2
(en)
|
2005-04-12 |
2012-09-25 |
Nektar Therapeutics |
Polymer-based compositions and conjugates of antimicrobial agents
|
WO2006116458A2
(en)
|
2005-04-26 |
2006-11-02 |
Coley Pharmaceutical Gmbh |
Modified oligoribonucleotide analogs with enhances immunostimulatory activity
|
CN109485727A
(zh)
|
2005-05-09 |
2019-03-19 |
小野药品工业株式会社 |
程序性死亡-1(pd-1)的人单克隆抗体及使用抗pd-1抗体来治疗癌症的方法
|
US20070072175A1
(en)
|
2005-05-13 |
2007-03-29 |
Biogen Idec Ma Inc. |
Nucleotide array containing polynucleotide probes complementary to, or fragments of, cynomolgus monkey genes and the use thereof
|
US20060265771A1
(en)
|
2005-05-17 |
2006-11-23 |
Lewis David L |
Monitoring microrna expression and function
|
DE102005023170A1
(de)
|
2005-05-19 |
2006-11-23 |
Curevac Gmbh |
Optimierte Formulierung für mRNA
|
CA2608818A1
(en)
|
2005-06-03 |
2006-12-14 |
Genentech, Inc. |
Method of producing antibodies with modified fucosylation level
|
US7550264B2
(en)
|
2005-06-10 |
2009-06-23 |
Datascope Investment Corporation |
Methods and kits for sense RNA synthesis
|
MX2007016314A
(es)
|
2005-06-16 |
2008-03-10 |
Nektar Therapeutics Al Corp |
Conjugados que tienen un enlace degradable y reactivos polimericos utiles en la preparacion de tales conjugados.
|
US8202835B2
(en)
|
2005-06-17 |
2012-06-19 |
Yitzchak Hillman |
Disease treatment via antimicrobial peptides or their inhibitors
|
US20110182805A1
(en)
|
2005-06-17 |
2011-07-28 |
Desimone Joseph M |
Nanoparticle fabrication methods, systems, and materials
|
US8101385B2
(en)
|
2005-06-30 |
2012-01-24 |
Archemix Corp. |
Materials and methods for the generation of transcripts comprising modified nucleotides
|
RU2008103346A
(ru)
|
2005-06-30 |
2009-08-10 |
Аркемикс Корп. (Us) |
Материалы и способы для получения полностью 2-модифицированных транскриптов нуклеиновых кислот
|
WO2007014363A2
(en)
|
2005-07-27 |
2007-02-01 |
Genentech, Inc. |
Vectors for inducible expression of hairpin rna and use thereof
|
EP3611266B1
(en)
|
2005-08-23 |
2022-11-09 |
The Trustees of the University of Pennsylvania |
Rna containing modified nucleosides and methods of use thereof
|
US9012219B2
(en)
*
|
2005-08-23 |
2015-04-21 |
The Trustees Of The University Of Pennsylvania |
RNA preparations comprising purified modified RNA for reprogramming cells
|
US20070048741A1
(en)
|
2005-08-24 |
2007-03-01 |
Getts Robert C |
Methods and kits for sense RNA synthesis
|
EP1928492B1
(en)
|
2005-09-01 |
2011-02-23 |
Celgene Corporation |
Immunological uses of immunodulatory compounds for vaccine and anti-infections disease therapy
|
WO2007026249A2
(en)
|
2005-09-01 |
2007-03-08 |
Novartis Vaccines And Diagnostics Gmbh & Co Kg |
Multiple vaccination including serogroup c meningococcus
|
US8420605B2
(en)
|
2005-09-07 |
2013-04-16 |
The University Of Strathclyde |
Hydrogel compositions
|
US20120021042A1
(en)
|
2005-09-15 |
2012-01-26 |
Steffen Panzner |
Efficient Method For Loading Amphoteric Liposomes With Nucleic Acid Active Substances
|
DE102005046490A1
(de)
|
2005-09-28 |
2007-03-29 |
Johannes-Gutenberg-Universität Mainz |
Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
|
US20070087437A1
(en)
|
2005-10-14 |
2007-04-19 |
Jifan Hu |
Methods for rejuvenating cells in vitro and in vivo
|
US20070105124A1
(en)
|
2005-11-08 |
2007-05-10 |
Getts Robert C |
Methods and kits for nucleic acid amplification
|
JP2009515539A
(ja)
|
2005-11-18 |
2009-04-16 |
バイオライン・リミテッド |
酵素的dnaポリメラーゼ反応を増強するための方法
|
EP1973576B1
(en)
|
2005-11-28 |
2019-05-15 |
Genmab A/S |
Recombinant monovalent antibodies and methods for production thereof
|
AU2005338632B2
(en)
|
2005-11-30 |
2010-05-20 |
Epicentre Technologies Corporation |
Selective terminal tagging of nucleic acids
|
TWI389709B
(zh)
|
2005-12-01 |
2013-03-21 |
Novartis Ag |
經皮治療系統
|
US8603457B2
(en)
|
2005-12-02 |
2013-12-10 |
University Of Rochester |
Nonsense suppression and genetic codon alteration by targeted modification
|
EP1954252B1
(en)
|
2005-12-02 |
2016-02-03 |
GlaxoSmithKline Biologicals SA |
Nanoparticles for use in immunogenic compositions
|
EP1969000A2
(en)
|
2005-12-06 |
2008-09-17 |
Centre National de la Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
US7579318B2
(en)
|
2005-12-06 |
2009-08-25 |
Centre De La Recherche De La Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
JP2009523410A
(ja)
|
2005-12-08 |
2009-06-25 |
ノバルティス アクチエンゲゼルシャフト |
遺伝子転写に対するfgfr3の阻害剤の効果
|
AU2006325975B2
(en)
|
2005-12-13 |
2011-12-08 |
Kyoto University |
Nuclear reprogramming factor
|
JP2009519033A
(ja)
|
2005-12-16 |
2009-05-14 |
ディアト |
核酸を細胞に送達するための細胞貫通ペプチド結合体
|
US8178660B2
(en)
|
2006-01-13 |
2012-05-15 |
The Trustees Of The University Of Pennsylvania |
Vaccines and immunotherapeutics using codon optimized IL-15 and methods for using the same
|
US20070178103A1
(en)
|
2006-01-30 |
2007-08-02 |
Fey Georg H |
CD19-specific immunotoxin and treatment method
|
US9458444B2
(en)
|
2006-02-03 |
2016-10-04 |
Opko Biologics Ltd. |
Long-acting coagulation factors and methods of producing same
|
US8476234B2
(en)
|
2006-02-03 |
2013-07-02 |
Prolor Biotech Inc. |
Long-acting coagulation factors and methods of producing same
|
US8946155B2
(en)
|
2006-02-03 |
2015-02-03 |
Opko Biologics Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
DE102006007433A1
(de)
|
2006-02-17 |
2007-08-23 |
Curevac Gmbh |
Adjuvanz in Form einer Lipid-modifizierten Nukleinsäure
|
EP1991560B1
(en)
|
2006-02-20 |
2018-04-04 |
Ewha University-Industry Collaboration Foundation |
Peptide having cell membrane penetrating activity
|
CN101420984B
(zh)
|
2006-02-21 |
2013-01-02 |
尼克塔治疗公司 |
嵌段可降解聚合物及由其制备的轭合物
|
US20080038278A1
(en)
|
2006-02-24 |
2008-02-14 |
Jingsong Cao |
GPAT3 encodes a mammalian, microsomal acyl-coa:glycerol 3- phosphate acyltransferase
|
CA2643322C
(en)
|
2006-02-24 |
2015-07-21 |
Novartis Ag |
Microparticles containing biodegradable polymer and cationic polysaccharide for use in immunogenic compositions
|
JP2009528359A
(ja)
|
2006-02-28 |
2009-08-06 |
エラン ファーマシューティカルズ,インコーポレイテッド |
ナタリズマブを用いて炎症性疾患および自己免疫性疾患を治療する方法
|
US7910152B2
(en)
|
2006-02-28 |
2011-03-22 |
Advanced Cardiovascular Systems, Inc. |
Poly(ester amide)-based drug delivery systems with controlled release rate and morphology
|
GB0605217D0
(en)
|
2006-03-15 |
2006-04-26 |
Novartis Ag |
Method and compositions for assessing acute rejection
|
US8231907B2
(en)
|
2006-03-21 |
2012-07-31 |
Morehouse School Of Medicine |
Nanoparticles for delivery of active agents
|
WO2008105773A2
(en)
|
2006-03-31 |
2008-09-04 |
Massachusetts Institute Of Technology |
System for targeted delivery of therapeutic agents
|
US8257685B2
(en)
|
2006-04-04 |
2012-09-04 |
Stc.Unm |
Swellable particles for drug delivery
|
EP1852127A1
(en)
|
2006-05-02 |
2007-11-07 |
Charité - Universitätsmedizin Berlin |
Use of a B-cell-depleting antibody for treatment of polyoma virus infections
|
JP5630998B2
(ja)
|
2006-05-15 |
2014-11-26 |
マサチューセッツ インスティテュート オブ テクノロジー |
機能的粒子のためのポリマー
|
AU2007253254B2
(en)
|
2006-05-24 |
2013-01-17 |
Merck Serono Sa |
Cladribine regimen for treating multiple sclerosis
|
EP2492684B1
(en)
|
2006-06-02 |
2016-12-28 |
President and Fellows of Harvard College |
Protein surface remodeling
|
JP5605895B2
(ja)
|
2006-07-04 |
2014-10-15 |
ゲンマブ エー/エス |
Copdを処置するためのcd20結合分子
|
ATE503469T1
(de)
|
2006-07-07 |
2011-04-15 |
Univ Aarhus |
Nanoteilchen zur abgabe von nukleinsäure
|
WO2008008752A2
(en)
|
2006-07-12 |
2008-01-17 |
Novartis Ag |
Actinically crosslinkable copolymers for manufacturing contact lenses
|
MX2009000622A
(es)
|
2006-07-20 |
2009-01-29 |
Novartis Ag |
Inhibidores de amigo-2-para tratar, diagnosticar o detectar cancer.
|
JP5571380B2
(ja)
|
2006-07-24 |
2014-08-13 |
ルミナス バイオサイエンシズ,インコーポレイテッド |
オストワルド熟成を減少させた水不溶性の医薬品物質の固体ナノ粒子処方物
|
EP2049665A2
(en)
|
2006-07-28 |
2009-04-22 |
Applera Corporation |
Dinucleotide mrna cap analogs
|
WO2008014979A2
(en)
|
2006-07-31 |
2008-02-07 |
Curevac Gmbh |
NUCLEIC ACID OF FORMULA (I): GIXmGn, OR (II): CIXmCn, IN PARTICULAR AS AN IMMUNE-STIMULATING AGENT/ADJUVANT
|
DE102006035618A1
(de)
|
2006-07-31 |
2008-02-07 |
Curevac Gmbh |
Nukleinsäure der Formel (I): GlXmGn, insbesondere als immunstimulierendes Adjuvanz
|
JP2010507567A
(ja)
|
2006-08-07 |
2010-03-11 |
ジェンザイム・コーポレーション |
併用療法
|
US8658211B2
(en)
|
2006-08-18 |
2014-02-25 |
Arrowhead Madison Inc. |
Polyconjugates for in vivo delivery of polynucleotides
|
EP2051965A2
(en)
|
2006-08-18 |
2009-04-29 |
Nastech Pharmaceutical Company Inc. |
Dicer substrate rna peptide conjugates and methods for rna therapeutics
|
JP5775260B2
(ja)
|
2006-09-06 |
2015-09-09 |
シー3 ジアン インコーポレイテッド |
選択的に標的化された抗菌性ペプチドおよびその使用
|
PL2059532T3
(pl)
|
2006-09-07 |
2013-05-31 |
Crucell Holland Bv |
Ludzkie cząsteczki wiążące zdolne do neutralizowania wirusa grypy H5N1 i ich zastosowania
|
CA2663003C
(en)
|
2006-09-08 |
2018-02-13 |
Justin Hanes |
Compositions and methods for enhancing transport through mucus
|
US8454948B2
(en)
|
2006-09-14 |
2013-06-04 |
Medgenics Medical Israel Ltd. |
Long lasting drug formulations
|
GB0619182D0
(en)
|
2006-09-29 |
2006-11-08 |
Leuven K U Res & Dev |
Oligonucleotide arrays
|
DK2068886T3
(da)
|
2006-10-03 |
2013-11-18 |
Tekmira Pharmaceuticals Corp |
Lipidholdige præparater
|
EP2073848B1
(en)
|
2006-10-05 |
2013-08-28 |
The Johns Hopkins University |
Water-dispersible oral, parenteral, and topical formulations for poorly water soluble drugs using smart polymeric nanoparticles
|
DE102006051516A1
(de)
|
2006-10-31 |
2008-05-08 |
Curevac Gmbh |
(Basen-)modifizierte RNA zur Expressionssteigerung eines Proteins
|
US8414927B2
(en)
|
2006-11-03 |
2013-04-09 |
Boston Scientific Scimed, Inc. |
Cross-linked polymer particles
|
US7999087B2
(en)
|
2006-11-15 |
2011-08-16 |
Agilent Technologies, Inc. |
2′-silyl containing thiocarbonate protecting groups for RNA synthesis
|
US8242258B2
(en)
|
2006-12-03 |
2012-08-14 |
Agilent Technologies, Inc. |
Protecting groups for RNA synthesis
|
US8399007B2
(en)
|
2006-12-05 |
2013-03-19 |
Landec Corporation |
Method for formulating a controlled-release pharmaceutical formulation
|
US7893227B2
(en)
|
2006-12-05 |
2011-02-22 |
Lasergen, Inc. |
3′-OH unblocked nucleotides and nucleosides base modified with non-cleavable, terminating groups and methods for their use in DNA sequencing
|
EA200900784A1
(ru)
|
2006-12-06 |
2009-12-30 |
Новартис Аг |
Вакцины, включающие антиген из четырех штаммов вируса гриппа
|
US9034348B2
(en)
|
2006-12-11 |
2015-05-19 |
Chi2Gel Ltd. |
Injectable chitosan mixtures forming hydrogels
|
RS52537B
(en)
|
2006-12-18 |
2013-04-30 |
Acceleron Pharma Inc. |
ACTIVIN-ACTRII ANTAGONISTS AND USES FOR ANEMIA TREATMENT
|
AU2007339280B2
(en)
|
2006-12-21 |
2013-12-05 |
Stryker Corporation |
Sustained-release formulations comprising crystals, macromolecular gels, and particulate suspensions of biologic agents
|
WO2008140615A2
(en)
|
2006-12-21 |
2008-11-20 |
Novozymes, Inc. |
Modified messenger rna stabilizing sequences for expressing genes in bacterial cells
|
DE102006061015A1
(de)
|
2006-12-22 |
2008-06-26 |
Curevac Gmbh |
Verfahren zur Reinigung von RNA im präparativen Maßstab mittels HPLC
|
AU2007337810B2
(en)
|
2006-12-22 |
2014-02-13 |
Archemix Corp. |
Materials and methods for the generation of transcripts comprising modified nucleotides
|
US8338166B2
(en)
|
2007-01-04 |
2012-12-25 |
Lawrence Livermore National Security, Llc |
Sorting, amplification, detection, and identification of nucleic acid subsequences in a complex mixture
|
DE102007001370A1
(de)
|
2007-01-09 |
2008-07-10 |
Curevac Gmbh |
RNA-kodierte Antikörper
|
WO2008091799A2
(en)
|
2007-01-22 |
2008-07-31 |
The Trustees Of Columbia University In The City Of New York |
Cell-based methods for identifying inhibitors of parkinson's disease-associated lrrk2 mutants
|
EP2423222B2
(en)
|
2007-01-30 |
2020-07-29 |
Epivax, Inc. |
Regulatory t cell epitopes, compositions and uses thereof
|
TW201627320A
(zh)
|
2007-02-02 |
2016-08-01 |
艾瑟勒朗法瑪公司 |
衍生自ActRIIB的變體與其用途
|
WO2008097926A2
(en)
|
2007-02-02 |
2008-08-14 |
Yale University |
Transient transfection with rna
|
WO2008096370A2
(en)
|
2007-02-05 |
2008-08-14 |
Natco Pharma Limited |
An efficient and novel purification method of recombinant hg-csf
|
US8333799B2
(en)
|
2007-02-12 |
2012-12-18 |
C. R. Bard, Inc. |
Highly flexible stent and method of manufacture
|
US8242087B2
(en)
|
2007-02-27 |
2012-08-14 |
K.U.Leuven Research & Development |
Phosphate modified nucleosides useful as substrates for polymerases and as antiviral agents
|
EP2126093B1
(en)
|
2007-03-02 |
2012-10-10 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Improvement of protein production
|
EP1964922A1
(en)
|
2007-03-02 |
2008-09-03 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Improvement of protein production
|
US7943168B2
(en)
|
2007-03-05 |
2011-05-17 |
Washington University |
Nanoparticle delivery systems comprising a hydrophobic core and a lipid/surfactant layer comprising a membrane-lytic peptide
|
WO2008115504A2
(en)
|
2007-03-20 |
2008-09-25 |
Millennium Pharmaceuticals, Inc. |
Nucleic acids encoding humanized immunoglobulin that binds a4b7 integrin
|
EP2136788B1
(en)
|
2007-03-30 |
2011-10-26 |
Bind Biosciences, Inc. |
Cancer cell targeting using nanoparticles
|
CN101707872B
(zh)
|
2007-04-27 |
2014-10-22 |
回声治疗有限公司 |
用于分析物感测或经皮给药的皮肤渗透装置
|
EP2606906A1
(en)
|
2007-04-30 |
2013-06-26 |
GlaxoSmithKline LLC |
Methods for administering anti-IL-5 antibodies
|
US8703204B2
(en)
|
2007-05-03 |
2014-04-22 |
Bend Research, Inc. |
Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
|
DK2494993T3
(en)
|
2007-05-04 |
2018-11-12 |
Marina Biotech Inc |
Amino acid lipids and uses thereof
|
US7682789B2
(en)
|
2007-05-04 |
2010-03-23 |
Ventana Medical Systems, Inc. |
Method for quantifying biomolecules conjugated to a nanoparticle
|
US8728491B2
(en)
|
2007-05-07 |
2014-05-20 |
Alba Therapeutics Corporation |
Transcutaneous delivery of therapeutic agents
|
JP5296328B2
(ja)
|
2007-05-09 |
2013-09-25 |
独立行政法人理化学研究所 |
1本鎖環状rnaおよびその製造方法
|
DK2476689T3
(en)
|
2007-05-10 |
2016-01-18 |
Agilent Technologies Inc |
Thiocarbonbeskyttende groups for RNA synthesis
|
SG10201503254TA
(en)
|
2007-05-14 |
2015-06-29 |
Medimmune Llc |
Methods of reducing eosinophil levels
|
WO2008144365A2
(en)
|
2007-05-17 |
2008-11-27 |
Novartis Ag |
Method for making dry powder compositions containing ds-rna based on supercritical fluid technology
|
EP2152737A2
(en)
|
2007-05-22 |
2010-02-17 |
Novartis Ag |
Methods of treating, diagnosing and detecting fgf21-associated disorders
|
AU2008259907B2
(en)
|
2007-05-30 |
2014-12-04 |
Northwestern University |
Nucleic acid functionalized nanoparticles for therapeutic applications
|
EP2164951A2
(en)
|
2007-05-30 |
2010-03-24 |
The General Hospital Corporation |
Methods of generating pluripotent cells from somatic cells
|
CA2692906C
(en)
|
2007-06-19 |
2016-01-19 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Synthesis and use of anti-reverse phosphorothioate analogs of the messenger rna cap
|
CA2707436C
(en)
|
2007-06-29 |
2014-01-28 |
Epicentre Technologies Corporation |
Copy dna and sense rna
|
WO2009015071A1
(en)
|
2007-07-23 |
2009-01-29 |
Dharmacon, Inc. |
Screening of micro-rna cluster inhibitor pools
|
US20090042825A1
(en)
|
2007-08-06 |
2009-02-12 |
Majed Matar |
Composition, method of preparation & application of concentrated formulations of condensed nucleic acids with a cationic lipopolymer
|
US9144546B2
(en)
|
2007-08-06 |
2015-09-29 |
Clsn Laboratories, Inc. |
Nucleic acid-lipopolymer compositions
|
KR20100063079A
(ko)
|
2007-08-23 |
2010-06-10 |
노파르티스 아게 |
올리고뉴클레오티드의 탐지 방법
|
WO2009030254A1
(en)
|
2007-09-04 |
2009-03-12 |
Curevac Gmbh |
Complexes of rna and cationic peptides for transfection and for immunostimulation
|
EP2197918B1
(en)
|
2007-09-05 |
2013-12-18 |
F. Hoffmann-La Roche AG |
Combination therapy with type i and type ii anti-cd20 antibodies
|
US8506928B2
(en)
|
2007-09-07 |
2013-08-13 |
The Regents Of The University Of California |
Methods and compounds for targeting tissues
|
DK3156414T3
(da)
|
2007-09-26 |
2020-03-09 |
Intrexon Corp |
Syntetisk 5'utrs ekspressionsvektorer og fremgangsmåder til øgning af transgen ekspression
|
EP2195009B1
(en)
|
2007-09-26 |
2014-07-30 |
Oregon Health and Science University |
Cyclic undecapeptides and derivatives as multiple sclerosis therapies
|
EP2042193A1
(en)
|
2007-09-28 |
2009-04-01 |
Biomay AG |
RNA Vaccines
|
WO2009046388A1
(en)
|
2007-10-03 |
2009-04-09 |
United States Medical Research & Material Command |
Cr-2 binding peptide p28 as molecular adjuvant for dna vaccines
|
WO2009046739A1
(en)
|
2007-10-09 |
2009-04-16 |
Curevac Gmbh |
Composition for treating prostate cancer (pca)
|
WO2009046738A1
(en)
|
2007-10-09 |
2009-04-16 |
Curevac Gmbh |
Composition for treating lung cancer, particularly of non-small lung cancers (nsclc)
|
MX2010003642A
(es)
|
2007-10-12 |
2010-08-09 |
Massachusetts Inst Technology |
Nanotecnologia de vacuna.
|
US20090098118A1
(en)
|
2007-10-15 |
2009-04-16 |
Thomas Friess |
Combination therapy of a type ii anti-cd20 antibody with an anti-bcl-2 active agent
|
EP2205277B1
(en)
|
2007-10-22 |
2017-07-26 |
Genmab A/S |
Novel antibody therapies
|
US8183345B2
(en)
|
2007-11-01 |
2012-05-22 |
University Of Rochester |
Recombinant factor VIII having reduced inactivation by activated protein C
|
RU2491095C2
(ru)
|
2007-11-09 |
2013-08-27 |
Новартис Аг |
Применения анти-cd40-антител
|
EP2223934B1
(en)
|
2007-11-14 |
2012-10-03 |
Institute Of Microbiology, Chinese Academy Of Sciences |
Polypeptides for inhibiting influenza virus infection
|
EP2222709B1
(en)
|
2007-11-30 |
2016-11-23 |
Glaxo Group Limited |
Antigen-binding constructs
|
CA2707042A1
(en)
|
2007-12-10 |
2009-06-18 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of factor vii gene
|
CN103911378A
(zh)
|
2007-12-11 |
2014-07-09 |
斯克利普斯研究所 |
涉及mRNA翻译增强因子的组合物和方法
|
WO2009076679A2
(en)
|
2007-12-13 |
2009-06-18 |
Alnylam Pharmaceuticals Inc. |
Methods and compositions for prevention or treatment of rsv infection
|
EP2072618A1
(en)
|
2007-12-14 |
2009-06-24 |
Johannes Gutenberg-Universität Mainz |
Use of RNA for reprogramming somatic cells
|
AU2008342956A1
(en)
|
2007-12-21 |
2009-07-09 |
Genentech, Inc. |
Therapy of rituximab-refractory rheumatoid arthritis patients
|
JP5526785B2
(ja)
|
2008-01-23 |
2014-06-18 |
味の素株式会社 |
L−アミノ酸の製造法
|
WO2009093384A1
(ja)
|
2008-01-24 |
2009-07-30 |
National Institute Of Advanced Industrial Science And Technology |
ポリヌクレオチド及びポリヌクレオチド類似体並びにこれらを用いた遺伝子発現制御方法
|
EP3346005A1
(en)
|
2008-01-31 |
2018-07-11 |
CureVac AG |
Nucleic acids of formula (i) (nuglxmgnnv)a and derivatives thereof as an immunostimulating agent/adjuvant
|
EP2250252A2
(en)
|
2008-02-11 |
2010-11-17 |
Cambridge Enterprise Limited |
Improved reprogramming of mammalian cells, and the cells obtained
|
EP2240155B1
(en)
|
2008-02-13 |
2012-06-06 |
Intarcia Therapeutics, Inc |
Devices, formulations, and methods for delivery of multiple beneficial agents
|
DE102008009920A1
(de)
|
2008-02-15 |
2009-08-20 |
Aj Innuscreen Gmbh |
Mobiles Gerät für die Nukleinsäureisolierung
|
US20120027813A1
(en)
|
2008-02-22 |
2012-02-02 |
Novartis Vaccines And Diagnostics Srl |
Adjuvanted influenza vaccines for pediatric use
|
US8506966B2
(en)
|
2008-02-22 |
2013-08-13 |
Novartis Ag |
Adjuvanted influenza vaccines for pediatric use
|
US20100004313A1
(en)
|
2008-02-29 |
2010-01-07 |
Tbd |
Modified Poloxamers for Gene Expression and Associated Methods
|
JP2011514423A
(ja)
|
2008-03-14 |
2011-05-06 |
エーゲン、インコーポレイテッド |
生分解性架橋分枝状ポリ(アルキレンイミン)
|
MY159517A
(en)
|
2008-03-14 |
2017-01-13 |
Biocon Ltd |
A monoclonal antibody and a method thereof
|
MX2010010667A
(es)
|
2008-03-28 |
2010-11-09 |
Glaxosmithkline Llc |
Metodos de tratamiento.
|
WO2009127060A1
(en)
|
2008-04-15 |
2009-10-22 |
Protiva Biotherapeutics, Inc. |
Novel lipid formulations for nucleic acid delivery
|
WO2009127230A1
(en)
|
2008-04-16 |
2009-10-22 |
Curevac Gmbh |
MODIFIED (m)RNA FOR SUPPRESSING OR AVOIDING AN IMMUNOSTIMULATORY RESPONSE AND IMMUNOSUPPRESSIVE COMPOSITION
|
KR20110042152A
(ko)
|
2008-04-25 |
2011-04-25 |
노쓰웨스턴유니버시티 |
콜레스테롤을 격리시키기에 적합한 나노구조
|
CN102066405B
(zh)
|
2008-04-28 |
2015-09-30 |
哈佛大学校长及研究员协会 |
用于细胞穿透的超荷电蛋白
|
BRPI0913012B1
(pt)
|
2008-04-30 |
2021-12-14 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention |
Quimera de ácido nucleico, métodos para detectar um anticorpo do vírus da dengue em uma amostra de um paciente, e para produzir partículas virais que expressam proteínas prm e e do vírus da dengue, uso de vírus codificado pela quimera e flavivírus ou partícula viral quiméricos
|
US9394538B2
(en)
|
2008-05-07 |
2016-07-19 |
Shi-Lung Lin |
Development of universal cancer drugs and vaccines
|
EP2323716B1
(en)
|
2008-05-08 |
2015-03-04 |
MiniPumps, LLC |
Drug-delivery pumps
|
US8697098B2
(en)
|
2011-02-25 |
2014-04-15 |
South Dakota State University |
Polymer conjugated protein micelles
|
KR101661636B1
(ko)
|
2008-05-13 |
2016-09-30 |
유니버시티 오브 워싱톤 |
세포로의 전달을 위한 이블록 공중합체 및 그의 폴리뉴클레오티드 복합체
|
US9738680B2
(en)
|
2008-05-21 |
2017-08-22 |
Rheinische Friedrich-Wilhelms-Universität Bonn |
5′ triphosphate oligonucleotide with blunt end and uses thereof
|
KR101275950B1
(ko)
|
2008-05-29 |
2013-06-25 |
한올바이오파마주식회사 |
증가된 단백질분해효소 저항성을 나타내는 변형된 에리스로포이에틴(epo) 폴리펩티드 및 이의 약제학적 조성물
|
FR2931824B1
(fr)
|
2008-05-29 |
2014-11-28 |
Centre Nat Rech Scient |
Procede de synthese d'arn par voie chimique.
|
WO2009148528A2
(en)
|
2008-05-30 |
2009-12-10 |
Millennium Pharmaceuticals, Inc. |
Assessment of chromosomal alterations to predict clinical outcome of bortezomib treatment
|
PL215513B1
(pl)
|
2008-06-06 |
2013-12-31 |
Univ Warszawski |
Nowe boranofosforanowe analogi dinukleotydów, ich zastosowanie, czasteczka RNA, sposób otrzymywania RNA oraz sposób otrzymywania peptydów lub bialka
|
TWI451876B
(zh)
|
2008-06-13 |
2014-09-11 |
Lilly Co Eli |
聚乙二醇化之離脯胰島素化合物
|
JP6363320B2
(ja)
|
2008-06-16 |
2018-07-25 |
ファイザー・インク |
薬剤を装填したポリマーナノ粒子及びその製造方法と使用方法
|
SI2285350T1
(en)
|
2008-06-16 |
2018-03-30 |
Pfizer Inc. |
Methods for the preparation of diblock copolymers functionalized with targeting agent for use in the manufacture of therapeutic nanoparticles
|
WO2010005726A2
(en)
|
2008-06-16 |
2010-01-14 |
Bind Biosciences Inc. |
Therapeutic polymeric nanoparticles with mtor inhibitors and methods of making and using same
|
US20100009424A1
(en)
|
2008-07-14 |
2010-01-14 |
Natasha Forde |
Sonoporation systems and methods
|
US20110250237A1
(en)
|
2008-07-15 |
2011-10-13 |
O'hagan Derek |
Immunogenic amphipathic peptide compositions
|
WO2010009065A2
(en)
|
2008-07-15 |
2010-01-21 |
Novartis Ag |
Amphipathic peptide compositions
|
EP2319923B1
(en)
*
|
2008-07-24 |
2013-12-25 |
Meiji Seika Pharma Co., Ltd. |
Pyripyropene a biosynthetic genes
|
WO2010025510A1
(en)
|
2008-09-03 |
2010-03-11 |
Xenome Ltd |
Libraries of peptide conjugates and methods for making them
|
WO2010028347A2
(en)
|
2008-09-05 |
2010-03-11 |
President & Fellows Of Harvard College |
Continuous directed evolution of proteins and nucleic acids
|
CN102439025B
(zh)
|
2008-09-06 |
2017-08-01 |
坎姆根公司 |
Rna合成-用于反向合成rna的亚磷酰胺,以及在3’‑末端合成rna的配体、发色团和修饰物的方便引入中的应用
|
US20120100558A1
(en)
|
2008-09-08 |
2012-04-26 |
Hanash Samir M |
Lung cancer diagnosis
|
WO2010030763A2
(en)
|
2008-09-10 |
2010-03-18 |
Bind Biosciences, Inc. |
High throughput fabrication of nanoparticles
|
AR073295A1
(es)
|
2008-09-16 |
2010-10-28 |
Genentech Inc |
Metodos para tratar la esclerosis multiple progresiva. articulo de fabricacion.
|
US20120021519A1
(en)
|
2008-09-19 |
2012-01-26 |
Presidents And Fellows Of Harvard College |
Efficient induction of pluripotent stem cells using small molecule compounds
|
WO2010037408A1
(en)
|
2008-09-30 |
2010-04-08 |
Curevac Gmbh |
Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof
|
WO2010042490A1
(en)
|
2008-10-06 |
2010-04-15 |
Boston Medical Center Corporation |
A single lentiviral vector system for induced pluripotent (ips) stem cells derivation
|
EP2350043B9
(en)
|
2008-10-09 |
2014-08-20 |
TEKMIRA Pharmaceuticals Corporation |
Improved amino lipids and methods for the delivery of nucleic acids
|
US8535655B2
(en)
|
2008-10-10 |
2013-09-17 |
Polyactiva Pty Ltd. |
Biodegradable polymer—bioactive moiety conjugates
|
US8343498B2
(en)
|
2008-10-12 |
2013-01-01 |
Massachusetts Institute Of Technology |
Adjuvant incorporation in immunonanotherapeutics
|
WO2010047765A2
(en)
|
2008-10-20 |
2010-04-29 |
Massachussetts Institute Of Technology |
Nanostructures for drug delivery
|
WO2010047839A1
(en)
|
2008-10-25 |
2010-04-29 |
Aura Biosciences |
Modified plant virus particles and uses therefor
|
US8969353B2
(en)
|
2008-11-07 |
2015-03-03 |
Massachusetts Institute Of Technology |
Aminoalcohol lipidoids and uses thereof
|
EP3207944B1
(en)
|
2008-11-10 |
2020-01-15 |
Arbutus Biopharma Corporation |
Novel lipids and compositions for the delivery of therapeutics
|
US8734853B2
(en)
|
2008-11-17 |
2014-05-27 |
University Of North Texas Health Science Center At Fort Worth |
HDL particles for delivery of nucleic acids
|
EP2191840A1
(en)
|
2008-11-28 |
2010-06-02 |
Sanofi-Aventis |
Antitumor combinations containing antibodies recognizing specifically CD38 and melphalan
|
NZ593618A
(en)
|
2008-12-10 |
2013-02-22 |
Alnylam Pharmaceuticals Inc |
Gnaq targeted dsrna compositions and methods for inhibiting expression
|
EP2196476A1
(en)
|
2008-12-10 |
2010-06-16 |
Novartis Ag |
Antibody formulation
|
US8563041B2
(en)
|
2008-12-12 |
2013-10-22 |
Bind Therapeutics, Inc. |
Therapeutic particles suitable for parenteral administration and methods of making and using same
|
WO2010068918A2
(en)
|
2008-12-12 |
2010-06-17 |
The Regents Of The University Of California |
Novel targets for treatment of hypercholesterolemia
|
WO2010075072A2
(en)
|
2008-12-15 |
2010-07-01 |
Bind Biosciences |
Long circulating nanoparticles for sustained release of therapeutic agents
|
EA201170940A1
(ru)
|
2009-01-16 |
2012-02-28 |
ГЛЭКСОСМИТКЛАЙН ЭлЭлСи |
Лечение рака с использованием комбинации бендамустина и анти-cd20-антитела
|
WO2010084371A1
(en)
|
2009-01-26 |
2010-07-29 |
Mitoprod |
Novel circular interfering rna molecules
|
EP3243504A1
(en)
|
2009-01-29 |
2017-11-15 |
Arbutus Biopharma Corporation |
Improved lipid formulation
|
WO2010088927A1
(en)
|
2009-02-09 |
2010-08-12 |
Curevac Gmbh |
Use of pei for the improvement of endosomal release and expression of transfected nucleic acids, complexed with cationic or polycationic compounds
|
US20140141089A1
(en)
|
2009-02-11 |
2014-05-22 |
Colorado School Of Mines |
Nanoparticles, Compositions Thereof, and Methods of Use, and Methods of Making the Same
|
EP2401365B1
(en)
|
2009-02-24 |
2016-04-27 |
The Scripps Research Institute |
Reengineering mrna primary structure for enhanced protein production
|
WO2010141135A2
(en)
|
2009-03-05 |
2010-12-09 |
Trustees Of Boston University |
Bacteriophages expressing antimicrobial peptides and uses thereof
|
US8685458B2
(en)
|
2009-03-05 |
2014-04-01 |
Bend Research, Inc. |
Pharmaceutical compositions of dextran polymer derivatives
|
WO2010105277A1
(en)
|
2009-03-13 |
2010-09-16 |
Egen, Inc. |
Compositions and methods for the delivery of biologically active rnas
|
CN102438978B
(zh)
|
2009-03-20 |
2017-02-22 |
Clsn实验室股份有限公司 |
聚胺衍生物
|
US20120095077A1
(en)
|
2009-03-23 |
2012-04-19 |
University Of Utah Research Foundation |
Methods and compositions related to modified guanine bases for controlling off-target effects in rna interference
|
JP5622254B2
(ja)
|
2009-03-31 |
2014-11-12 |
国立大学法人東京大学 |
二本鎖リボ核酸ポリイオンコンプレックス
|
WO2011005341A2
(en)
|
2009-04-03 |
2011-01-13 |
University Of Chicago |
Compositions and methods related to protein a (spa) variants
|
ES2845212T3
(es)
|
2009-04-13 |
2021-07-26 |
Inst Nat Sante Rech Med |
Partículas de HPV y usos de las mismas
|
WO2010121141A1
(en)
|
2009-04-17 |
2010-10-21 |
Biogen Idec Ma Inc. |
Compositions and methods to treat acute myelogenous leukemia
|
EP2421563B1
(en)
|
2009-04-22 |
2017-04-12 |
Massachusetts Institute of Technology |
Innate immune suppression enables repeated delivery of long rna molecules
|
CA2993053A1
(en)
|
2009-04-27 |
2010-11-04 |
Novartis Ag |
Antagonistic activin receptor iib (actriib) antibodies for increasing muscle growth
|
US8715736B2
(en)
|
2009-04-30 |
2014-05-06 |
Florida Agricultural And Mechanical University |
Nanoparticle formulations for skin delivery
|
WO2010127159A2
(en)
|
2009-04-30 |
2010-11-04 |
Intezyne Technologies, Incorporated |
Polymeric micelles for polynucleotide encapsulation
|
JP5769701B2
(ja)
|
2009-05-05 |
2015-08-26 |
テクミラ ファーマシューティカルズ コーポレイションTekmira Pharmaceuticals Corporation |
脂質組成物
|
DE202009007116U1
(de)
|
2009-05-18 |
2010-10-14 |
Amoena Medizin-Orthopädie-Technik GmbH |
Antidekubituskissen
|
US8574835B2
(en)
|
2009-05-29 |
2013-11-05 |
Life Technologies Corporation |
Scaffolded nucleic acid polymer particles and methods of making and using
|
EP2440556A1
(en)
|
2009-06-10 |
2012-04-18 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of phosphatidylinositol 3-kinase
|
AU2010259984B2
(en)
|
2009-06-10 |
2017-03-09 |
Arbutus Biopharma Corporation |
Improved lipid formulation
|
EP2442792A4
(en)
|
2009-06-15 |
2015-12-23 |
Alnylam Pharmaceuticals Inc |
DOUBLE STRANDED RNA IN LIPID FORMULATION TARGETING THE PCSK9 GENE
|
US20110097329A1
(en)
|
2009-06-26 |
2011-04-28 |
Massachusetts Institute Of Technology |
Compositions and methods for treating cancer and modulating stress granule formation
|
IL292615B2
(en)
|
2009-07-01 |
2023-11-01 |
Protiva Biotherapeutics Inc |
Nucleic acid-lipid particles, preparations containing them and their uses
|
US8569256B2
(en)
|
2009-07-01 |
2013-10-29 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods for the delivery of therapeutic agents
|
US20110300205A1
(en)
|
2009-07-06 |
2011-12-08 |
Novartis Ag |
Self replicating rna molecules and uses thereof
|
DE102009033507A1
(de)
*
|
2009-07-15 |
2011-01-20 |
Niro-Plan Ag |
Vorrichtung und Verfahren zum Erzeugen von gekühltem Kaffee
|
JP5785168B2
(ja)
|
2009-07-31 |
2015-09-24 |
エスリス ゲーエムベーハーethris GmbH |
タンパク質発現用未修飾および修飾ヌクレオチドの組み合わせを有するrna
|
EP2281579A1
(en)
|
2009-08-05 |
2011-02-09 |
BioNTech AG |
Vaccine composition comprising 5'-Cap modified RNA
|
US20110053829A1
(en)
|
2009-09-03 |
2011-03-03 |
Curevac Gmbh |
Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids
|
US20110070227A1
(en)
|
2009-09-18 |
2011-03-24 |
Anna-Marie Novotney-Barry |
Treatment of Autoimmune and Inflammatory Diseases
|
US8859284B2
(en)
|
2009-10-22 |
2014-10-14 |
The United States Of America, As Represented By The Secretary Of The Navy |
Delivery of nanoparticles to neurons
|
US8449916B1
(en)
|
2009-11-06 |
2013-05-28 |
Iowa State University Research Foundation, Inc. |
Antimicrobial compositions and methods
|
WO2011060250A1
(en)
|
2009-11-13 |
2011-05-19 |
Bend Research, Inc. |
Cationic dextran polymer derivatives
|
WO2011062965A2
(en)
|
2009-11-18 |
2011-05-26 |
University Of Washington Through Its Center For Commercialization |
Targeting monomers and polymers having targeting blocks
|
US8530429B2
(en)
|
2009-11-24 |
2013-09-10 |
Arch Cancer Therapeutics, Inc. |
Brain tumor targeting peptides and methods
|
ES2713852T3
(es)
|
2009-12-01 |
2019-05-24 |
Translate Bio Inc |
Derivado de esteroides para la administración de ARNm en enfermedades genéticas humanas
|
US20110245756A1
(en)
|
2009-12-03 |
2011-10-06 |
Rishi Arora |
Devices for material delivery, electroporation, sonoporation, and/or monitoring electrophysiological activity
|
BR112012013502A2
(pt)
|
2009-12-06 |
2017-01-10 |
Biogen Idec Hemophilia Inc |
"polipeptídeos quiméricos e híbridos de fator viii-fc, e métodos de uso dos mesmos".
|
US20130189741A1
(en)
|
2009-12-07 |
2013-07-25 |
Cellscript, Inc. |
Compositions and methods for reprogramming mammalian cells
|
WO2011071860A2
(en)
|
2009-12-07 |
2011-06-16 |
Alnylam Pharmaceuticals, Inc. |
Compositions for nucleic acid delivery
|
PL3287525T3
(pl)
|
2009-12-07 |
2020-05-18 |
The Trustees Of The University Of Pennsylvania |
Preparaty RNA zawierające oczyszczony zmodyfikowany RNA do przeprogramowywania komórek
|
WO2011069529A1
(en)
|
2009-12-09 |
2011-06-16 |
Curevac Gmbh |
Mannose-containing solution for lyophilization, transfection and/or injection of nucleic acids
|
WO2011069528A1
(en)
|
2009-12-09 |
2011-06-16 |
Curevac Gmbh |
Lyophilization of nucleic acids in lactate-containing solutions
|
TR201906255T4
(tr)
|
2009-12-11 |
2019-05-21 |
Pfizer |
Terapötik partiküllerin liyofilize edilmesine yönelik stabil formülasyonlar.
|
EA201290497A1
(ru)
|
2009-12-15 |
2013-01-30 |
Байнд Байосайенсиз, Инк. |
Терапевтические полимерные наночастицы, включающие кортикостероиды, и способы получения таковых
|
EP2515942B1
(en)
|
2009-12-15 |
2020-02-12 |
Pfizer Inc. |
Therapeutic polymeric nanoparticle compositions with high glass transition temperature or high molecular weight copolymers
|
WO2011084620A2
(en)
|
2009-12-16 |
2011-07-14 |
Brigham And Women's Hospital, Inc. |
Particles for multiple agent delivery
|
DE102009058769A1
(de)
|
2009-12-16 |
2011-06-22 |
MagForce Nanotechnologies AG, 10589 |
Temperaturabhängige Aktivierung von katalytischen Nukleinsäuren zur kontrollierten Wirkstofffreisetzung
|
AU2010330814B2
(en)
|
2009-12-18 |
2017-01-12 |
Acuitas Therapeutics Inc. |
Methods and compositions for delivery of nucleic acids
|
EP3721943A1
(en)
|
2009-12-23 |
2020-10-14 |
Novartis AG |
Lipids, lipid compositions and methods of using them
|
US8846631B2
(en)
|
2010-01-14 |
2014-09-30 |
Regulus Therapeutics Inc. |
MicroRNA compositions and methods
|
SI2539451T1
(sl)
|
2010-02-24 |
2016-04-29 |
Arrowhead Research Corporation |
Sestavki za ciljano dostavo sirna
|
US8889193B2
(en)
|
2010-02-25 |
2014-11-18 |
The Johns Hopkins University |
Sustained delivery of therapeutic agents to an eye compartment
|
WO2011112608A1
(en)
|
2010-03-08 |
2011-09-15 |
University Of Rochester |
Synthesis of nanoparticles using reducing gases
|
CA2793373A1
(en)
|
2010-03-16 |
2011-09-22 |
University Of Utah Research Foundation |
Cleavable modifications to reducible poly (amido ethylenimines)s to enhance nucleotide delivery
|
WO2011116072A1
(en)
|
2010-03-16 |
2011-09-22 |
Escape Therapeutics, Inc. |
Hybrid hydrogel scaffold compositions and methods of use
|
US20110230816A1
(en)
|
2010-03-18 |
2011-09-22 |
Tyco Healthcare Group Lp |
Gels for Transdermal Delivery
|
US9149432B2
(en)
|
2010-03-19 |
2015-10-06 |
Massachusetts Institute Of Technology |
Lipid vesicle compositions and methods of use
|
US20110237975A1
(en)
|
2010-03-24 |
2011-09-29 |
United States Endoscopy Group, Inc. |
Multiple biopsy device
|
GB201005005D0
(en)
|
2010-03-25 |
2010-05-12 |
Angeletti P Ist Richerche Bio |
New vaccine
|
US8207290B2
(en)
|
2010-03-26 |
2012-06-26 |
Cerulean Pharma Inc. |
Methods and systems for generating nanoparticles
|
EP2553019A1
(en)
|
2010-03-26 |
2013-02-06 |
Mersana Therapeutics, Inc. |
Modified polymers for delivery of polynucleotides, method of manufacture, and methods of use thereof
|
US20110247090A1
(en)
|
2010-04-02 |
2011-10-06 |
Intrexon Corporation |
Synthetic 5'UTRs, Expression Vectors, and Methods for Increasing Transgene Expression
|
EP2555794A4
(en)
|
2010-04-05 |
2014-01-15 |
Univ Chicago |
PROTEIN A (SPA) ANTIBODY COMPOSITIONS AND METHODS AS AN IMMUNE RESPONSE AMPLIFIER
|
US20130037977A1
(en)
|
2010-04-08 |
2013-02-14 |
Paul A. Burke |
Preparation of Lipid Nanoparticles
|
US20110250264A1
(en)
|
2010-04-09 |
2011-10-13 |
Pacira Pharmaceuticals, Inc. |
Method for formulating large diameter synthetic membrane vesicles
|
CA2795695A1
(en)
|
2010-04-09 |
2011-10-13 |
The University Of Tokyo |
Microrna-controlled recombinant vaccinia virus and use thereof
|
KR101196667B1
(ko)
|
2010-04-15 |
2012-11-02 |
포항공과대학교 산학협력단 |
피에이치 민감성 금속 나노 입자를 이용한 항암제 전달 시스템
|
EP2377938A1
(en)
|
2010-04-16 |
2011-10-19 |
Eukarys |
Capping-prone RNA polymerase enzymes and their applications
|
US8802438B2
(en)
|
2010-04-16 |
2014-08-12 |
Children's Medical Center Corporation |
Compositions, kits, and methods for making induced pluripotent stem cells using synthetic modified RNAs
|
SI2558577T1
(sl)
|
2010-04-16 |
2019-05-31 |
Nuevolution A/S |
Bifunkcionalni kompleksi in metode za pripravo in uporabo takšnih kompleksov
|
US20130260460A1
(en)
|
2010-04-22 |
2013-10-03 |
Isis Pharmaceuticals Inc |
Conformationally restricted dinucleotide monomers and oligonucleotides
|
EP2563455A4
(en)
|
2010-04-28 |
2014-02-19 |
Kimberly Clark Co |
METHOD FOR INCREASING THE PERMEABILITY OF AN EPITHELIAL BARRIER
|
WO2011139911A2
(en)
|
2010-04-29 |
2011-11-10 |
Isis Pharmaceuticals, Inc. |
Lipid formulated single stranded rna
|
MX2012012615A
(es)
|
2010-04-30 |
2012-12-17 |
Novartis Ag |
Marcadores predictivos utiles en el tratamiento del sindrome fragil x (fxs).
|
US9254327B2
(en)
|
2010-05-10 |
2016-02-09 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for delivery of active agents
|
EP2569276B1
(en)
|
2010-05-12 |
2021-02-24 |
Arbutus Biopharma Corporation |
Novel cationic lipids and methods of use thereof
|
WO2011141704A1
(en)
|
2010-05-12 |
2011-11-17 |
Protiva Biotherapeutics, Inc |
Novel cyclic cationic lipids and methods of use
|
EP2387999A1
(en)
|
2010-05-21 |
2011-11-23 |
CureVac GmbH |
Histidine-containing solution for transfection and/or injection of nucleic acids and uses thereof
|
US8802863B2
(en)
|
2010-05-24 |
2014-08-12 |
Sirna Therapeutics, Inc. |
Amino alcohol cationic lipids for oligonucleotide delivery
|
WO2011153120A1
(en)
|
2010-06-04 |
2011-12-08 |
Merck Sharp & Dohme Corp. |
Novel low molecular weight cationic lipids for oligonucleotide delivery
|
JP5726299B2
(ja)
|
2010-06-14 |
2015-05-27 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
細胞透過性ペプチドおよびその使用
|
WO2011163121A1
(en)
|
2010-06-21 |
2011-12-29 |
Alnylam Pharmaceuticals, Inc. |
Multifunctional copolymers for nucleic acid delivery
|
CA2803239A1
(en)
|
2010-06-25 |
2011-12-29 |
Novartis Ag |
Combinations of meningococcal factor h binding proteins
|
JP5635690B2
(ja)
|
2010-07-01 |
2014-12-03 |
ポステック アカデミー‐インダストリー ファウンデーション |
細菌由来マイクロベシクルを用いた癌治療及び癌診断方法
|
AU2011274367B2
(en)
|
2010-07-02 |
2015-04-23 |
The University Of Chicago |
Compositions and methods related to protein A (SpA) variants
|
EP2590625B1
(en)
|
2010-07-06 |
2017-09-20 |
GlaxoSmithKline Biologicals SA |
Cationic oil-in-water emulsions
|
EP2590670B1
(en)
|
2010-07-06 |
2017-08-23 |
GlaxoSmithKline Biologicals SA |
Methods of raising an immune response by delivery of rna
|
RS54489B1
(en)
|
2010-07-06 |
2016-06-30 |
Glaxosmithkline Biologicals Sa |
LIPOSOMS WITH LIPIDS THAT HAVE IMPROVED PKA VALUE FOR RNA RELEASE
|
LT2590676T
(lt)
|
2010-07-06 |
2016-10-25 |
Glaxosmithkline Biologicals Sa |
Viriono tipo išnešiojančios dalelės, skirtos besireplikuojančioms rnr molekulėms
|
US9770463B2
(en)
|
2010-07-06 |
2017-09-26 |
Glaxosmithkline Biologicals Sa |
Delivery of RNA to different cell types
|
US9192661B2
(en)
|
2010-07-06 |
2015-11-24 |
Novartis Ag |
Delivery of self-replicating RNA using biodegradable polymer particles
|
PT2591114T
(pt)
|
2010-07-06 |
2016-08-02 |
Glaxosmithkline Biologicals Sa |
Imunização de mamíferos de grande porte com doses baixas de arn
|
EP3508573A1
(en)
|
2010-07-09 |
2019-07-10 |
Bioverativ Therapeutics Inc. |
Systems for factor viii processing and methods thereof
|
KR20230156435A
(ko)
|
2010-07-09 |
2023-11-14 |
바이오버라티브 테라퓨틱스 인크. |
인자 ix 폴리펩티드 및 이들의 사용 방법
|
US20130177523A1
(en)
|
2010-07-13 |
2013-07-11 |
University Of Utah Research Foundation |
Gold particles and methods of making and using the same in cancer treatment
|
GB201012410D0
(en)
|
2010-07-23 |
2010-09-08 |
Medical Res Council |
Intracellular immunity
|
AU2011285200B2
(en)
|
2010-07-30 |
2014-08-21 |
CureVac SE |
Complexation of nucleic acids with disulfide-crosslinked cationic components for transfection and immunostimulation
|
EP2600901B1
(en)
|
2010-08-06 |
2019-03-27 |
ModernaTX, Inc. |
A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof
|
WO2012021516A2
(en)
|
2010-08-09 |
2012-02-16 |
The Trustees Of The University Of Pennsylvania |
Nanoparticle-oligonucletide hybrid structures and methods of use thereof
|
WO2012019630A1
(en)
|
2010-08-13 |
2012-02-16 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded protein
|
US20130142868A1
(en)
|
2010-08-20 |
2013-06-06 |
University Of Washington |
Circumferential Aerosol Device for Delivering Drugs to Olfactory Epithelium and Brain
|
CA2808901A1
(en)
|
2010-08-20 |
2012-02-23 |
Cerulean Pharma Inc. |
Conjugates, particles, compositions, and related methods
|
CA2808965C
(en)
|
2010-08-20 |
2020-01-07 |
Novartis Ag |
Soluble needle arrays for delivery of influenza vaccines
|
ES2935542T3
(es)
|
2010-08-31 |
2023-03-07 |
Glaxosmithkline Biologicals Sa |
Liposomas pequeños para la administración de ARN que codifica para inmunógeno
|
PL3970742T3
(pl)
|
2010-08-31 |
2022-09-19 |
Glaxosmithkline Biologicals S.A. |
Pegylowane liposomy do dostarczania rna kodującego immunogen
|
EP4226935A3
(en)
|
2010-08-31 |
2023-09-06 |
Theraclone Sciences, Inc. |
Human immunodeficiency virus (hiv)-neutralizing antibodies
|
JP5908477B2
(ja)
|
2010-08-31 |
2016-04-26 |
ノバルティス アーゲー |
タンパク質をコードするrnaのリポソームによる送達に適した脂質
|
EP3406730B1
(en)
|
2010-08-31 |
2022-02-23 |
Sirna Therapeutics, Inc. |
Novel single chemical entities and methods for delivery of oligonucleotides
|
US9549901B2
(en)
|
2010-09-03 |
2017-01-24 |
The Brigham And Women's Hospital, Inc. |
Lipid-polymer hybrid particles
|
EP2614074A1
(en)
|
2010-09-09 |
2013-07-17 |
The University of Chicago |
Methods and compositions involving protective staphylococcal antigens
|
WO2012034077A2
(en)
|
2010-09-09 |
2012-03-15 |
The University Of Chicago |
Compositions and methods related to attenuated staphylococcal strains
|
WO2012039979A2
(en)
|
2010-09-10 |
2012-03-29 |
The Johns Hopkins University |
Rapid diffusion of large polymeric nanoparticles in the mammalian brain
|
US8466122B2
(en)
|
2010-09-17 |
2013-06-18 |
Protiva Biotherapeutics, Inc. |
Trialkyl cationic lipids and methods of use thereof
|
ES2888231T3
(es)
|
2010-09-20 |
2022-01-03 |
Sirna Therapeutics Inc |
Lípidos catiónicos de bajo peso molecular para el suministro de oligonucleótidos
|
US20130183718A1
(en)
|
2010-09-21 |
2013-07-18 |
RibpxX GmbH |
Method for Synthesizing RNA using DNA Template
|
EP2618821A4
(en)
|
2010-09-24 |
2014-08-13 |
Brigham & Womens Hospital |
NANOSTRUCTURED GELS FOR CONTROLLED RELEASE OF CAPSUED MEDIUM
|
WO2012050975A2
(en)
|
2010-09-29 |
2012-04-19 |
The University Of North Carolina At Chapel Hill |
Novel circular mammalian rna molecules and uses thereof
|
WO2012044638A1
(en)
|
2010-09-30 |
2012-04-05 |
Merck Sharp & Dohme Corp. |
Low molecular weight cationic lipids for oligonucleotide delivery
|
CN104531671A
(zh)
|
2010-10-01 |
2015-04-22 |
现代治疗公司 |
设计核酸及其使用方法
|
US10078075B2
(en)
|
2011-12-09 |
2018-09-18 |
Vanderbilt University |
Integrated organ-on-chip systems and applications of the same
|
EP3485913A1
(en)
|
2010-10-21 |
2019-05-22 |
Sirna Therapeutics, Inc. |
Low molecular weight cationic lipids for oligonucleotide delivery
|
EP2632485A4
(en)
|
2010-10-29 |
2014-05-28 |
Merck Sharp & Dohme |
RECOMBINANT SUBUNIT VACCINE AGAINST DENGUE VIRUS
|
WO2012061703A1
(en)
|
2010-11-05 |
2012-05-10 |
The Johns Hopkins University |
Compositions and methods relating to reduced mucoadhesion
|
WO2012064429A2
(en)
|
2010-11-09 |
2012-05-18 |
The Regents Of The University Of California |
Skin permeating and cell entering (space) peptides and methods of use thereof
|
MX346784B
(es)
|
2010-11-12 |
2017-03-31 |
Inovio Pharmaceuticals Inc |
Antigenos prostaticos de consenso, molecula de acido nucleico que los codifica y vacuna y usos que los comprenden.
|
EP2640426B1
(en)
|
2010-11-16 |
2016-02-03 |
Selecta Biosciences, Inc. |
Immunostimulatory oligonucleotides
|
DK2640842T3
(en)
|
2010-11-17 |
2018-08-13 |
Aduro Biotech Inc |
Methods and compositions for inducing an immune response to EGFRVIII
|
ES2697606T3
(es)
|
2010-11-19 |
2019-01-25 |
Idera Pharmaceuticals Inc |
Compuestos de oligonucleótido inmunorregulador (IRO) para modular la respuesta inmunitaria basada en un receptor tipo Toll
|
US8853377B2
(en)
|
2010-11-30 |
2014-10-07 |
Shire Human Genetic Therapies, Inc. |
mRNA for use in treatment of human genetic diseases
|
WO2012072096A1
(en)
|
2010-12-03 |
2012-06-07 |
Biontech Ag |
Method for cellular rna expression
|
EP2651445A2
(en)
|
2010-12-16 |
2013-10-23 |
SPRNA GmbH |
Pharmaceutical composition consisting of rna having alkali metal as counter ion and formulated with dications
|
US8501930B2
(en)
|
2010-12-17 |
2013-08-06 |
Arrowhead Madison Inc. |
Peptide-based in vivo siRNA delivery system
|
EP2655614B1
(en)
|
2010-12-22 |
2017-03-15 |
President and Fellows of Harvard College |
Continuous directed evolution
|
WO2012089225A1
(en)
|
2010-12-29 |
2012-07-05 |
Curevac Gmbh |
Combination of vaccination and inhibition of mhc class i restricted antigen presentation
|
ES2605990T3
(es)
|
2010-12-29 |
2017-03-17 |
F. Hoffmann-La Roche Ag |
Conjugados de molécula pequeña para la administración intracelular de ácidos nucleicos
|
US10364440B2
(en)
|
2011-01-04 |
2019-07-30 |
Brown University |
Nanotubes as carriers of nucleic acids into cells
|
WO2012094574A2
(en)
|
2011-01-06 |
2012-07-12 |
The Johns Hopkins University |
Stabilized polyribonucleotide nanoparticles
|
WO2012094653A2
(en)
|
2011-01-07 |
2012-07-12 |
Massachusetts Institute Of Technology |
Compositions and methods for macromolecular drug delivery
|
DK3202760T3
(da)
|
2011-01-11 |
2019-11-25 |
Alnylam Pharmaceuticals Inc |
Pegylerede lipider og deres anvendelse til lægemiddelfremføring
|
US20120189700A1
(en)
|
2011-01-19 |
2012-07-26 |
Zoraida Aguilar |
Nanoparticle Based Immunological Stimulation
|
WO2012101235A1
(en)
|
2011-01-26 |
2012-08-02 |
Cenix Bioscience Gmbh |
Delivery system and conjugates for compound delivery via naturally occurring intracellular transport routes
|
US10363309B2
(en)
|
2011-02-04 |
2019-07-30 |
Case Western Reserve University |
Targeted nanoparticle conjugates
|
US20140066363A1
(en)
|
2011-02-07 |
2014-03-06 |
Arun K. Bhunia |
Carbohydrate nanoparticles for prolonged efficacy of antimicrobial peptide
|
WO2012116715A1
(en)
|
2011-03-02 |
2012-09-07 |
Curevac Gmbh |
Vaccination in newborns and infants
|
US20120207840A1
(en)
|
2011-02-10 |
2012-08-16 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Diagnostic Or Therapeutic Agents For The Treatment Of Non-Melanoma Skin Cancer
|
AU2012217788A1
(en)
|
2011-02-14 |
2013-08-29 |
Swift Biosciences, Inc. |
Polynucleotide primers and probes
|
WO2012112689A1
(en)
|
2011-02-15 |
2012-08-23 |
The University Of North Carolina At Chapel Hill |
Nanoparticle, liposomes, polymers, agents and proteins modified with reversible linkers
|
WO2012112730A2
(en)
|
2011-02-15 |
2012-08-23 |
Merrimack Pharmaceuticals, Inc. |
Compositions and methods for delivering nucleic acid to a cell
|
EP2489371A1
(en)
|
2011-02-18 |
2012-08-22 |
Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria |
Carrier peptides for drug delivery
|
WO2012113413A1
(en)
|
2011-02-21 |
2012-08-30 |
Curevac Gmbh |
Vaccine composition comprising complexed immunostimulatory nucleic acids and antigens packaged with disulfide-linked polyethyleneglycol/peptide conjugates
|
WO2012115980A1
(en)
|
2011-02-22 |
2012-08-30 |
California Institute Of Technology |
Delivery of proteins using adeno-associated virus (aav) vectors
|
US8696637B2
(en)
|
2011-02-28 |
2014-04-15 |
Kimberly-Clark Worldwide |
Transdermal patch containing microneedles
|
ES2681698T3
(es)
|
2011-03-02 |
2018-09-14 |
Glaxosmithkline Biologicals Sa |
Vacunas de combinación con menores dosis de antígeno y/o adyuvante
|
WO2012116714A1
(en)
|
2011-03-02 |
2012-09-07 |
Curevac Gmbh |
Vaccination in elderly patients
|
EP2683812A4
(en)
|
2011-03-07 |
2014-12-03 |
Massachusetts Inst Technology |
METHODS FOR TRANSFECTING CELLS WITH NUCLEIC ACIDS
|
WO2012125680A1
(en)
|
2011-03-16 |
2012-09-20 |
Novartis Ag |
Methods of treating vasculitis using an il-17 binding molecule
|
WO2012125987A2
(en)
|
2011-03-17 |
2012-09-20 |
Massachusetts Institute Of Technology |
Delivery system
|
CN103429759A
(zh)
|
2011-03-17 |
2013-12-04 |
诺华股份有限公司 |
Fgfr及其配体作为hr阳性对象中乳腺癌的生物标记
|
US10357568B2
(en)
|
2011-03-24 |
2019-07-23 |
Glaxosmithkline Biologicals S.A. |
Adjuvant nanoemulsions with phospholipids
|
CA2831392C
(en)
|
2011-03-28 |
2020-04-28 |
Massachusetts Institute Of Technology |
Conjugated lipomers and uses thereof
|
US20140005070A1
(en)
|
2011-03-28 |
2014-01-02 |
Novartis Ag |
Markers associated with cyclin-dependent kinase inhibitors
|
CA2831613A1
(en)
|
2011-03-31 |
2012-10-04 |
Moderna Therapeutics, Inc. |
Delivery and formulation of engineered nucleic acids
|
JP2014511694A
(ja)
|
2011-04-03 |
2014-05-19 |
ザ ジェネラル ホスピタル コーポレーション ドゥーイング ビジネス アズ マサチューセッツ ジェネラル ホスピタル |
修飾型rna(mod−rna)を使用する効率的なインビボタンパク質発現
|
WO2012138530A1
(en)
|
2011-04-04 |
2012-10-11 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
2'-o-aminooxymethyl nucleoside derivatives for use in the synthesis and modification of nucleosides, nucleotides and oligonucleotides
|
WO2012142132A1
(en)
|
2011-04-11 |
2012-10-18 |
Life Technologies Corporation |
Polymer particles and methods of making and using same
|
WO2012142240A1
(en)
|
2011-04-13 |
2012-10-18 |
The Trustees Of The University Of Pennsylvania |
Coated mesoporous nanoparticles
|
WO2013158127A1
(en)
|
2012-04-16 |
2013-10-24 |
Molecular Transfer, Inc. |
Agents for improved delivery of nucleic acids to eukaryotic cells
|
US20140178894A1
(en)
|
2011-04-20 |
2014-06-26 |
Novartis Forschungsstiftung, Zweigniederlassung |
Culture medium suitable for the culture of undifferentiated cells
|
JP2014518620A
(ja)
|
2011-04-26 |
2014-08-07 |
モレキュラー エクスプレス,インコーポレイテッド |
リポソーム製剤
|
JP2014512409A
(ja)
|
2011-04-28 |
2014-05-22 |
エスティーシー. ユーエヌエム |
標的送達用の多孔性ナノ粒子に担持された脂質二重層(プロトセル)及びその使用方法
|
WO2012149536A1
(en)
|
2011-04-28 |
2012-11-01 |
The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. |
Neutralizing antibodies to nipah and hendra virus
|
WO2012149246A1
(en)
|
2011-04-29 |
2012-11-01 |
Novartis Ag |
Methods of treating squamous cell carcinoma related applications
|
CA3182519A1
(en)
|
2011-04-29 |
2012-11-01 |
Selecta Biosciences, Inc. |
Tolerogenic synthetic nanocarriers for antigen-specific deletion of t effector cells
|
UA116189C2
(uk)
|
2011-05-02 |
2018-02-26 |
Мілленніум Фармасьютікалз, Інк. |
КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА
|
WO2012151234A2
(en)
|
2011-05-02 |
2012-11-08 |
Wayne State University |
A protein-induced pluripotent cell technology uses thereof
|
US8945588B2
(en)
|
2011-05-06 |
2015-02-03 |
The University Of Chicago |
Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
|
EP2707116A1
(de)
|
2011-05-10 |
2014-03-19 |
Basf Se |
Öl-in-wasser-emulsionen
|
US9283279B2
(en)
|
2011-05-11 |
2016-03-15 |
Ramot At Tel-Aviv University Ltd. |
Targeted polymeric conjugates and uses thereof
|
WO2012152910A1
(en)
|
2011-05-12 |
2012-11-15 |
Helmut Vockner |
Novel pharmaceutical formulation
|
JP2014519493A
(ja)
|
2011-05-12 |
2014-08-14 |
イッサム・リサーチ・ディベロップメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシティ・オブ・エルサレム・リミテッド |
ポリマー共役脂質を含むリポソームおよび関連用途
|
LT3275892T
(lt)
|
2011-05-13 |
2020-04-10 |
Glaxosmithkline Biologicals S.A. |
Struktūros prieš suliejimą rsv f antigenai
|
US8691750B2
(en)
|
2011-05-17 |
2014-04-08 |
Axolabs Gmbh |
Lipids and compositions for intracellular delivery of biologically active compounds
|
BR112013029490A2
(pt)
|
2011-05-17 |
2019-09-24 |
Moderna Therapeutics Inc |
ácidos nucleicos projetados e métodos de uso dos mesmos para vertebrados não humanos
|
WO2012162174A1
(en)
|
2011-05-20 |
2012-11-29 |
Kohler Co. |
Toilet installation system and method
|
MX340453B
(es)
|
2011-05-25 |
2016-07-08 |
Novartis Ag |
Biomarcadores para cancer de pulmon.
|
US20140308363A1
(en)
|
2011-05-31 |
2014-10-16 |
Bind Therapeutics, Inc. |
Drug loaded polymeric nanoparticles and methods of making and using same
|
RU2602185C2
(ru)
|
2011-06-02 |
2016-11-10 |
Новартис Аг |
Биомаркеры для терапии на основе ингибитора hedgehog
|
CN103857387B
(zh)
|
2011-06-02 |
2017-03-15 |
加利福尼亚大学董事会 |
膜包封的纳米颗粒及使用方法
|
WO2012168259A1
(en)
|
2011-06-06 |
2012-12-13 |
Novartis Forschungsstiftung, Zweigniederlassung |
Protein tyrosine phosphatase, non-receptor type 11 (ptpn11) and triple-negative breast cancer
|
JP6022557B2
(ja)
|
2011-06-08 |
2016-11-09 |
シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド |
切断可能な脂質
|
IL280771B2
(en)
|
2011-06-08 |
2024-03-01 |
Shire Human Genetic Therapies |
Preparations of lipid nanoparticles and methods for administration of mRNA
|
WO2012170607A2
(en)
|
2011-06-10 |
2012-12-13 |
Novartis Ag |
Use of pcsk9 antagonists
|
US8636696B2
(en)
|
2011-06-10 |
2014-01-28 |
Kimberly-Clark Worldwide, Inc. |
Transdermal device containing microneedles
|
WO2012168491A1
(en)
|
2011-06-10 |
2012-12-13 |
Novartis Ag |
Pharmaceutical formulations of pcsk9 antagonists
|
US8916696B2
(en)
|
2011-06-12 |
2014-12-23 |
City Of Hope |
Aptamer-mRNA conjugates for targeted protein or peptide expression and methods for their use
|
WO2012172495A1
(en)
|
2011-06-14 |
2012-12-20 |
Novartis Ag |
Compositions and methods for antibodies targeting tem8
|
US9457183B2
(en)
|
2011-06-15 |
2016-10-04 |
Tripep Ab |
Injection needle and device
|
JP2014519338A
(ja)
|
2011-06-16 |
2014-08-14 |
ノバルティス アーゲー |
治療薬として使用される可溶性タンパク質
|
CN103732749B
(zh)
|
2011-06-20 |
2017-03-29 |
高等教育联邦系统-匹兹堡大学 |
计算优化的宽反应性的h1n1流感抗原
|
WO2013003475A1
(en)
|
2011-06-27 |
2013-01-03 |
Cellscript, Inc. |
Inhibition of innate immune response
|
KR20230156804A
(ko)
|
2011-06-28 |
2023-11-14 |
이노비오 파마수티컬즈, 인크. |
최소 침습 피부 전기천공 장치
|
PT2726099T
(pt)
|
2011-07-01 |
2018-11-13 |
Novartis Ag |
Método para o tratamento de distúrbios metabólicos
|
EP2729182A4
(en)
|
2011-07-04 |
2014-12-24 |
Commw Scient Ind Res Org |
NUCLEIC COMPLEX
|
EP2729126B1
(en)
|
2011-07-06 |
2020-12-23 |
GlaxoSmithKline Biologicals SA |
Liposomes having useful n:p ratio for delivery of rna molecules
|
JP2014520807A
(ja)
|
2011-07-06 |
2014-08-25 |
ノバルティス アーゲー |
免疫原性組成物およびその使用
|
US11896636B2
(en)
|
2011-07-06 |
2024-02-13 |
Glaxosmithkline Biologicals Sa |
Immunogenic combination compositions and uses thereof
|
CA2840965C
(en)
|
2011-07-06 |
2021-03-02 |
Novartis Ag |
Cationic oil-in-water emulsions
|
EP3424495A1
(en)
|
2011-07-06 |
2019-01-09 |
GlaxoSmithKline Biologicals S.A. |
Oil-in-water emulsions that contain nucleic acids
|
WO2013006824A2
(en)
|
2011-07-07 |
2013-01-10 |
Life Technologies Corporation |
Polymer particles, nucleic acid polymer particles and methods of making and using the same
|
WO2013009736A2
(en)
|
2011-07-10 |
2013-01-17 |
President And Fellows Of Harvard College |
Compositions and methods for self-assembly of polymers with complementary macroscopic and microscopic scale units
|
US20130012566A1
(en)
|
2011-07-10 |
2013-01-10 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Diagnostic Or Therapeutic Agents For The Treatment of Alopecia
|
WO2013009717A1
(en)
|
2011-07-10 |
2013-01-17 |
Elisabet De Los Pinos |
Virion derived protein nanoparticles for delivering diagnostic or therapeutic agents for the treatment of skin-related diseases
|
US20140148503A1
(en)
|
2011-07-20 |
2014-05-29 |
University Of Iowa Research Foundation |
Nucleic acid aptamers
|
GB2492999A
(en)
|
2011-07-20 |
2013-01-23 |
Univ Central Lancashire |
Neutron detector
|
EP2734184B1
(en)
|
2011-07-21 |
2018-03-28 |
Croda International Plc |
Branched polyether-polyamide block copolymers and methods of making and using the same
|
WO2013016460A1
(en)
|
2011-07-25 |
2013-01-31 |
Novartis Ag |
Compositions and methods for assessing functional immunogenicity of parvovirus vaccines
|
US9493549B2
(en)
|
2011-07-25 |
2016-11-15 |
The Rockefeller University |
Antibodies directed toward the HIV-1 GP120 CD4 binding site with increased potency and breadth
|
US10933129B2
(en)
|
2011-07-29 |
2021-03-02 |
Selecta Biosciences, Inc. |
Methods for administering synthetic nanocarriers that generate humoral and cytotoxic T lymphocyte responses
|
CN103906535B
(zh)
|
2011-08-15 |
2017-07-14 |
芝加哥大学 |
与葡萄球菌蛋白a的抗体相关的组合物和方法
|
BR112014004585A2
(pt)
|
2011-08-26 |
2017-06-13 |
Arrowhead Res Corp |
polímeros de poli(éster vinílico) para liberação de ácido nucleico in vivo
|
BR112014004544A2
(pt)
|
2011-08-31 |
2017-04-04 |
Mallinckrodt Llc |
modificação com peg de nanopartículas com h-fosfonatos
|
SG11201400250UA
(en)
|
2011-08-31 |
2014-03-28 |
Novartis Ag |
Pegylated liposomes for delivery of immunogen-encoding rna
|
US9126966B2
(en)
|
2011-08-31 |
2015-09-08 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods of use thereof
|
WO2013033620A1
(en)
|
2011-09-01 |
2013-03-07 |
Irm Llc |
Compounds and compositions as pdgfr kinase inhibitors
|
EA201490553A1
(ru)
|
2011-09-02 |
2014-08-29 |
Новартис Аг |
Органические композиции для лечения связанных с hsf1 заболеваний
|
EP3384938A1
(en)
|
2011-09-12 |
2018-10-10 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
EP2755986A4
(en)
|
2011-09-12 |
2015-05-20 |
Moderna Therapeutics Inc |
MODIFIED NUCLEIC ACIDS AND METHODS OF USE
|
US9358284B2
(en)
|
2011-09-14 |
2016-06-07 |
Glaxosmithkline Biologicals Sa |
Methods for making saccharide-protein glycoconjugates
|
WO2013044219A1
(en)
|
2011-09-22 |
2013-03-28 |
Bind Biosciences |
Methods of treating cancers with therapeutic nanoparticles
|
WO2013072929A2
(en)
|
2011-09-23 |
2013-05-23 |
Indian Institute Of Technology |
Nanop article based cosmetic composition
|
TW201315742A
(zh)
|
2011-09-26 |
2013-04-16 |
Novartis Ag |
治療代謝病症之雙功能蛋白質
|
UY34346A
(es)
|
2011-09-26 |
2013-04-30 |
Novartis Ag |
Proteínas de fusión para tratar trastornos metabólicos
|
EP3456317A1
(en)
|
2011-09-27 |
2019-03-20 |
Alnylam Pharmaceuticals, Inc. |
Di-aliphatic substituted pegylated lipids
|
WO2013045505A1
(en)
|
2011-09-28 |
2013-04-04 |
Novartis Ag |
Biomarkers for raas combination therapy
|
EP3682905B1
(en)
*
|
2011-10-03 |
2021-12-01 |
ModernaTX, Inc. |
Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
|
WO2013055971A1
(en)
|
2011-10-11 |
2013-04-18 |
Arizona Board Of Regents For And On Behalf Of Arizona State University |
Polymers for delivering a substance into a cell
|
RU2014118727A
(ru)
|
2011-10-11 |
2015-11-20 |
Новартис Аг |
Рекомбинантные самореплицирующиеся полицистронные молекулы рнк
|
US20190209690A9
(en)
|
2011-10-12 |
2019-07-11 |
The Johns Hopkins University |
Bioreducible Poly (Beta-Amino Ester)s For siRNA Delivery
|
EP2766407B1
(en)
|
2011-10-12 |
2018-06-27 |
The Curators Of The University Of Missouri |
Pentablock polymers
|
JP2014530816A
(ja)
|
2011-10-14 |
2014-11-20 |
ノバルティスアーゲー |
Wnt経路関連疾患のための抗体および方法
|
CN104023711A
(zh)
|
2011-10-14 |
2014-09-03 |
Stc.Unm公司 |
用于靶向递送(包括负载物的透皮递送)的多孔纳米颗粒支撑的脂质双层(原始细胞)及其方法
|
JP2015501178A
(ja)
|
2011-10-18 |
2015-01-15 |
ミセル テクノロジーズ,インク. |
薬物送達のための医療用デバイス
|
DK2768958T3
(da)
|
2011-10-18 |
2019-09-16 |
Dicerna Pharmaceuticals Inc |
Kationiske aminlipider og anvendelser deraf
|
BR112014007485B1
(pt)
|
2011-10-20 |
2022-05-31 |
Novartis Ag |
Métodos para prever responsividade terapêutica de um indivíduo a tratamento com um ativador do receptor de acetilcolina nicotínico alfa 7, e usos do referido ativador
|
US20140248320A1
(en)
|
2011-10-20 |
2014-09-04 |
Novartis Ag |
Adjuvanted influenza b virus vaccines for pediatric priming
|
EP3069785A1
(en)
|
2011-10-25 |
2016-09-21 |
The University Of British Columbia |
Limit size lipid nanoparticles and related methods
|
WO2013061290A1
(en)
|
2011-10-26 |
2013-05-02 |
Nanopass Technologies Ltd. |
Microneedle intradermal drug delivery device with auto-disable functionality
|
NZ747501A
(en)
|
2011-10-27 |
2020-05-29 |
Massachusetts Inst Technology |
Amino acid derivatives functionalized on the n-terminal capable of forming drug encapsulating microspheres
|
JP6100271B2
(ja)
|
2011-10-27 |
2017-03-22 |
キンバリー クラーク ワールドワイド インコーポレイテッド |
高粘性生理活性薬剤の経皮的送達
|
CA2851828A1
(en)
|
2011-10-28 |
2013-05-02 |
Presage Biosciences, Inc. |
Methods for drug delivery
|
WO2013062140A1
(en)
|
2011-10-28 |
2013-05-02 |
Kyoto University |
Method for efficiently inducing differentiation of pluripotent stem cells into hepatic lineage cells
|
EP2771033A4
(en)
|
2011-10-28 |
2016-02-17 |
Integritybio Inc |
PROTEIN FORMULATIONS CONTAINING AMINO ACIDS
|
EP4218937A3
(en)
|
2011-10-31 |
2023-10-25 |
F. Hoffmann-La Roche AG |
Anti-il13 antibody formulations
|
ES2694154T3
(es)
|
2011-10-31 |
2018-12-18 |
Mallinckrodt Llc |
Composiciones de liposomas combinatorias para el tratamiento del cáncer
|
ES2666856T3
(es)
|
2011-11-04 |
2018-05-08 |
Novartis Ag |
Proteína 6 relacionada con lipoproteínas de baja densidad (LRP6) - constructos extensores de la vida media
|
CA2853685C
(en)
|
2011-11-04 |
2019-09-03 |
Nitto Denko Corporation |
Single use system for sterilely producing lipid-nucleic acid particles
|
US9579338B2
(en)
|
2011-11-04 |
2017-02-28 |
Nitto Denko Corporation |
Method of producing lipid nanoparticles for drug delivery
|
US10449257B2
(en)
|
2011-11-04 |
2019-10-22 |
Agency For Science, Technology And Research |
Self-assembled composite ultrasmall peptide-polymer hydrogels
|
US9872870B2
(en)
|
2011-11-04 |
2018-01-23 |
University Of Notre Dame Du Lac |
Multifunctional micellar nanoparticle-based drug and targeting agent system
|
US20130116408A1
(en)
|
2011-11-05 |
2013-05-09 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Radioisotopes For The Diagnosis And Treatment Of Malignant And Systemic Disease And The Monitoring Of Therapy
|
US20130115247A1
(en)
|
2011-11-05 |
2013-05-09 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Radioisotopes For The Diagnosis And Treatment Of Malignant And Systemic Disease And The Monitoring Of Therapy
|
WO2013068431A1
(en)
|
2011-11-08 |
2013-05-16 |
Novartis Forschungsstiftung, Zweigniederlassung, Friedrich Miescher Institute For Biomedical Research |
New treatment for neurodegenerative diseases
|
US20140294732A1
(en)
|
2011-11-08 |
2014-10-02 |
Novartis Forschungsstiftung, Zweigniederlassung, Friedrich Miescher Institute |
Early diagnostic of neurodegenerative diseases
|
EP2776459A1
(en)
|
2011-11-08 |
2014-09-17 |
Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research |
Rod cell-specific promoter
|
WO2013070872A1
(en)
|
2011-11-08 |
2013-05-16 |
The Board Of Trustees Of The University Of Arkansas |
Methods and compositions for x-ray induced release from ph sensitive liposomes
|
US9581590B2
(en)
|
2011-11-09 |
2017-02-28 |
Board Of Trustees Of Michigan State University |
Metallic nanoparticle synthesis with carbohydrate capping agent
|
WO2013071047A1
(en)
|
2011-11-11 |
2013-05-16 |
Children's Medical Center Corporation |
Compositions and methods for in vitro transcription of rna
|
EP3854416A1
(en)
|
2011-11-11 |
2021-07-28 |
Variation Biotechnologies Inc. |
Compositions and methods for treatment of cytomegalovirus
|
JP2014533290A
(ja)
|
2011-11-14 |
2014-12-11 |
ノバルティス アーゲー |
ポリアニオン性カルボマーとEnvポリペプチドとの免疫原性複合体ならびにその製造法および使用法
|
RU2014124184A
(ru)
|
2011-11-15 |
2015-12-27 |
Новартис Аг |
Комбинация ингибитора фосфоинозитид-3-киназы и модулятора пути янус-киназы 2 - проводника сигнала и активатора транскрипции 5
|
CN103957898B
(zh)
|
2011-11-18 |
2016-02-24 |
瑞泽恩制药公司 |
聚合物蛋白微粒
|
EP2783014A1
(en)
|
2011-11-21 |
2014-10-01 |
Novartis AG |
Methods of treating psoriatic arthritis (psa) using il-17 antagonists and psa response or non- response alleles
|
WO2013078199A2
(en)
|
2011-11-23 |
2013-05-30 |
Children's Medical Center Corporation |
Methods for enhanced in vivo delivery of synthetic, modified rnas
|
EP2785326A2
(en)
|
2011-11-29 |
2014-10-08 |
The University of North Carolina at Chapel Hill |
Geometrically engineered particles and methods for modulating macrophage or immune responses
|
CA2857502C
(en)
|
2011-11-30 |
2019-08-13 |
3M Innovative Properties Company |
Microneedle device including a peptide therapeutic agent and an amino acid and methods of making and using the same
|
US9364549B2
(en)
|
2011-11-30 |
2016-06-14 |
Andreas Voigt |
Hydrophobic drug-delivery material, method for manufacturing thereof and methods for delivery of a drug-delivery composition
|
WO2013082590A1
(en)
|
2011-12-02 |
2013-06-06 |
Invivo Therapeutics Corporation |
Peg based hydrogel for peripheral nerve injury applications and compositions and method of use of synthetic hydrogel sealants
|
WO2013082529A1
(en)
|
2011-12-02 |
2013-06-06 |
Yale University |
Enzymatic synthesis of poly(amine-co-esters) and methods of use thereof for gene delivery
|
US9248096B2
(en)
|
2011-12-02 |
2016-02-02 |
Pegasus Laboratories, Inc. |
Amphipathic lipid-based sustained release compositions
|
JP6564187B2
(ja)
|
2011-12-05 |
2019-08-21 |
ナノ プレシジョン メディカル インコーポレイテッドNano Precision Medical, Inc. |
チタニアナノチューブ膜を有する、薬物送達用デバイス
|
US8497124B2
(en)
|
2011-12-05 |
2013-07-30 |
Factor Bioscience Inc. |
Methods and products for reprogramming cells to a less differentiated state
|
KR20210134808A
(ko)
|
2011-12-05 |
2021-11-10 |
팩터 바이오사이언스 인크. |
세포를 형질감염시키는 방법들 및 생성물들
|
WO2013086373A1
(en)
|
2011-12-07 |
2013-06-13 |
Alnylam Pharmaceuticals, Inc. |
Lipids for the delivery of active agents
|
GB201121070D0
(en)
|
2011-12-07 |
2012-01-18 |
Isis Innovation |
composition for delivery of biotherapeutics
|
AU2012347637B2
(en)
|
2011-12-07 |
2017-09-14 |
Alnylam Pharmaceuticals, Inc. |
Biodegradable lipids for the delivery of active agents
|
JP6305343B2
(ja)
|
2011-12-07 |
2018-04-04 |
アルニラム・ファーマシューティカルズ・インコーポレーテッド |
活性薬剤の送達のための分岐アルキルおよびシクロアルキルを末端とする生分解性脂質
|
US10087422B2
(en)
|
2011-12-09 |
2018-10-02 |
President And Fellows Of Harvard College |
Organ chips and uses thereof
|
WO2013086486A1
(en)
|
2011-12-09 |
2013-06-13 |
President And Fellows Of Harvard College |
Integrated human organ-on-chip microphysiological systems
|
EP2787977A4
(en)
|
2011-12-09 |
2015-05-06 |
Univ California |
LIPOSOMAL ACTIVE INVERTING
|
AU2012353463B2
(en)
|
2011-12-12 |
2017-08-24 |
Kyowa Hakko Kirin Co., Ltd. |
Lipid nanoparticles containing combinations of cationic lipids
|
TWI594767B
(zh)
|
2011-12-12 |
2017-08-11 |
協和醱酵麒麟有限公司 |
含有陽離子性脂質之藥物傳遞系統用脂質奈米粒子
|
JP6407028B2
(ja)
|
2011-12-12 |
2018-10-17 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
MRSAのPBP2a及びその断片を含むタンパク質、それをコードする核酸、並びにMRSA感染を予防する及び治療するための組成物及びそれらの使用
|
US9844598B2
(en)
|
2011-12-13 |
2017-12-19 |
Engeneic Molecular Delivery Pty Ltd |
Bacterially derived, intact minicells for delivery of therapeutic agents to brain tumors
|
US20150000936A1
(en)
|
2011-12-13 |
2015-01-01 |
Schlumberger Technology Corporation |
Energization of an element with a thermally expandable material
|
EP2604253A1
(en)
|
2011-12-13 |
2013-06-19 |
Otto Glatter |
Water-in-oil emulsions and methods for their preparation
|
WO2013130161A1
(en)
|
2011-12-14 |
2013-09-06 |
modeRNA Therapeutics |
Methods of responding to a biothreat
|
WO2013087083A1
(en)
|
2011-12-15 |
2013-06-20 |
Biontech Ag |
Particles comprising single stranded rna and double stranded rna for immunomodulation
|
US20140349320A1
(en)
|
2011-12-15 |
2014-11-27 |
The Trustees Of The University Of Pennsylvania |
Using Adaptive Immunity to Detect Drug Resistance
|
ES2923757T3
(es)
|
2011-12-16 |
2022-09-30 |
Modernatx Inc |
Composiciones de ARNm modificado
|
KR20140103939A
(ko)
|
2011-12-16 |
2014-08-27 |
노파르티스 아게 |
흡입 프로파일-비의존적 약물 전달을 위한 에어로졸화 장치
|
WO2013090601A2
(en)
|
2011-12-16 |
2013-06-20 |
Massachusetts Institute Of Technology |
Compact nanoparticles for biological applications
|
US9573996B2
(en)
|
2011-12-16 |
2017-02-21 |
Synthon Biopharmaceuticals B.V. |
Monoclonal antibodies to human proinflammatory cytokines and methods for treating inflammatory diseases
|
BR112014014599A2
(pt)
|
2011-12-16 |
2017-06-13 |
Massachusetts Inst Technology |
polímeros de alfa-aminoamidina e uso dos mesmos
|
WO2013090842A2
(en)
|
2011-12-16 |
2013-06-20 |
Allergan, Inc. |
Ophthalmic compositions comprising polyvinyl capralactam-polyvinyl acetate-polyethylene glycol graft copolymers
|
ES2627856T3
(es)
|
2011-12-19 |
2017-07-31 |
The University Of Sydney |
Material compuesto de péptido-hidrogel
|
US9241829B2
(en)
|
2011-12-20 |
2016-01-26 |
Abbott Medical Optics Inc. |
Implantable intraocular drug delivery apparatus, system and method
|
JP2015510495A
(ja)
|
2011-12-21 |
2015-04-09 |
モデルナ セラピューティクス インコーポレイテッドModerna Therapeutics,Inc. |
器官または器官移植片の生存可能性または寿命を延長する方法
|
EP2793941A1
(en)
|
2011-12-23 |
2014-10-29 |
F.Hoffmann-La Roche Ag |
Articles of manufacture and methods for co-administration of antibodies
|
US10814115B2
(en)
|
2011-12-27 |
2020-10-27 |
Massachusetts Institute Of Technology |
Microneedle devices and uses thereof
|
JP2015505309A
(ja)
|
2011-12-29 |
2015-02-19 |
ノバルティス アーゲー |
髄膜炎菌h因子結合タンパク質のアジュバントされた組み合わせ
|
MX367352B
(es)
|
2012-01-06 |
2019-08-16 |
Gemphire Therapeutics Inc |
Metodos para reducir el riesgo de padecer una enfermedad cardiovascular.
|
KR20140129054A
(ko)
|
2012-01-26 |
2014-11-06 |
라이프 테크놀로지스 코포레이션 |
바이러스의 감염성을 증가시키는 방법
|
US20150017703A1
(en)
|
2012-01-26 |
2015-01-15 |
Life Technologies Corporation |
Methods for increasing the infectivity of viruses
|
EP2623121A1
(en)
|
2012-01-31 |
2013-08-07 |
Bayer Innovation GmbH |
Pharmaceutical composition comprising a polymeric carrier cargo complex and an antigen
|
WO2013113326A1
(en)
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen
|
WO2013113325A1
(en)
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Negatively charged nucleic acid comprising complexes for immunostimulation
|
CN104245745B
(zh)
|
2012-02-09 |
2017-03-29 |
生命技术公司 |
亲水性聚合物颗粒及其制备方法
|
US20140037573A1
(en)
|
2012-02-22 |
2014-02-06 |
Cerulean Pharma Inc. |
Conjugates, particles, compositions, and related methods
|
US20130243867A1
(en)
|
2012-02-23 |
2013-09-19 |
University Of South Florida (A Florida Non-Profit Corporation) |
Micelle compositions and methods for their use
|
US20130224268A1
(en)
|
2012-02-27 |
2013-08-29 |
Newgen Biopharma Corp. |
Topical delivery of hormonal and non hormonal nano formulations, methods of making and using the same
|
MX353382B
(es)
|
2012-03-01 |
2018-01-10 |
Amgen Res Munich Gmbh |
Moleculas de union polipeptido de larga duracion.
|
WO2013136234A1
(en)
|
2012-03-13 |
2013-09-19 |
University Of Kwazulu-Natal |
Transdermal delivery devices
|
US10322089B2
(en)
|
2012-03-14 |
2019-06-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Nanoparticles, nanoparticle delivery methods, and systems of delivery
|
EP2825206A1
(en)
|
2012-03-16 |
2015-01-21 |
The Johns Hopkins University |
Controlled release formulations for the delivery of hif-1 inhibitors
|
US10159743B2
(en)
|
2012-03-16 |
2018-12-25 |
The Johns Hopkins University |
Non-linear multiblock copolymer-drug conjugates for the delivery of active agents
|
NO2825156T3
(lt)
|
2012-03-16 |
2017-12-23 |
|
|
WO2013142349A1
(en)
|
2012-03-23 |
2013-09-26 |
University Of Chicago |
Compositions and methods related to staphylococcal sbi
|
US9610346B2
(en)
|
2012-03-23 |
2017-04-04 |
International Aids Vaccine Initiative |
Recombinant viral vectors
|
EP2830991A1
(en)
|
2012-03-26 |
2015-02-04 |
President and Fellows of Harvard College |
Lipid-coated nucleic acid nanostructures of defined shape
|
WO2013143555A1
(en)
|
2012-03-26 |
2013-10-03 |
Biontech Ag |
Rna formulation for immunotherapy
|
SG11201405542UA
(en)
|
2012-03-27 |
2014-10-30 |
Curevac Gmbh |
Artificial nucleic acid molecules
|
CN104284979B
(zh)
|
2012-03-27 |
2018-06-08 |
库瑞瓦格股份公司 |
用于提高的蛋白或肽表达的人工核酸分子
|
WO2013148541A1
(en)
|
2012-03-27 |
2013-10-03 |
Merck Sharp & Dohme Corp. |
DIETHER BASED BIODEGRADABLE CATIONIC LIPIDS FOR siRNA DELIVERY
|
CN108929880A
(zh)
|
2012-03-27 |
2018-12-04 |
库瑞瓦格股份公司 |
包含5′toputr的人工核酸分子
|
EP3865123A1
(en)
|
2012-03-29 |
2021-08-18 |
Translate Bio, Inc. |
Lipid-derived neutral nanoparticles
|
AU2013243953A1
(en)
|
2012-04-02 |
2014-10-30 |
Modernatx, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
WO2013151666A2
(en)
|
2012-04-02 |
2013-10-10 |
modeRNA Therapeutics |
Modified polynucleotides for the production of biologics and proteins associated with human disease
|
US9303079B2
(en)
|
2012-04-02 |
2016-04-05 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
JP6375289B2
(ja)
|
2012-04-05 |
2018-08-15 |
マサチューセッツ インスティテュート オブ テクノロジー |
免疫刺激組成物およびその使用方法
|
EP2833926A4
(en)
|
2012-04-05 |
2015-11-25 |
Univ Florida |
NEUROPHILIC NANOPARTICLES
|
WO2013152351A2
(en)
|
2012-04-06 |
2013-10-10 |
The Trustees Of Columbia University In The City Of New York |
Fusion polypeptides and methods of use thereof
|
WO2013153550A2
(en)
|
2012-04-08 |
2013-10-17 |
Theracoat Ltd |
Reverse thermal hydrogel preparations for use in the treatment of disorders of the urothelium
|
MX340992B
(es)
|
2012-04-11 |
2016-08-03 |
Intezyne Tech Inc |
Copolimeros de bloque para micelas estables.
|
EP3939572B1
(en)
|
2012-04-12 |
2024-03-27 |
Yale University |
Vehicles for controlled delivery of different pharmaceutical agents
|
WO2013154766A1
(en)
|
2012-04-13 |
2013-10-17 |
New York University |
Microrna control of ldl receptor pathway
|
US11001797B2
(en)
|
2012-04-13 |
2021-05-11 |
President And Fellows Of Harvard College |
Devices and methods for in vitro aerosol delivery
|
WO2013158141A1
(en)
|
2012-04-18 |
2013-10-24 |
Arrowhead Research Corporation |
Poly(acrylate) polymers for in vivo nucleic acid delivery
|
US9402816B2
(en)
|
2012-04-19 |
2016-08-02 |
Sima Therapeutics, Inc. |
Diester and triester based low molecular weight, biodegradeable cationic lipids for oligonucleotide delivery
|
WO2013163234A1
(en)
|
2012-04-23 |
2013-10-31 |
Massachusetts Institute Of Technology |
Stable layer-by-layer coated particles
|
US8969317B2
(en)
|
2012-04-25 |
2015-03-03 |
Regulus Therapeutics Inc. |
MicroRNA compounds and methods for modulating miR-21 activity
|
EP2844295A1
(en)
|
2012-05-03 |
2015-03-11 |
Kala Pharmaceuticals, Inc. |
Pharmaceutical nanoparticles showing improved mucosal transport
|
JP6392209B2
(ja)
|
2012-05-04 |
2018-09-19 |
ザ・ジョンズ・ホプキンス・ユニバーシティー |
粘液内層を通過する迅速な透過のための脂質ベース薬物キャリア
|
US20150087671A1
(en)
|
2012-05-16 |
2015-03-26 |
Micell Technologies, Inc. |
Low burst sustained release lipophilic and biologic agent compositions
|
WO2013173582A1
(en)
|
2012-05-17 |
2013-11-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Hepatitis c virus neutralizing antibody
|
WO2013173693A1
(en)
|
2012-05-18 |
2013-11-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Nanoparticles with enhanced entry into cancer cells
|
AU2013266232B2
(en)
|
2012-05-23 |
2017-08-03 |
The Ohio State University |
Lipid nanoparticle compositions for antisense oligonucleotides delivery
|
ES2719598T3
(es)
|
2012-05-25 |
2019-07-11 |
Curevac Ag |
Inmovilización reversible y/o liberación controlada de ácidos nucleicos contenidos en nanopartículas mediante revestimientos poliméricos (biodegradables)
|
KR102165138B1
(ko)
|
2012-06-06 |
2020-10-14 |
로마 비스타 메디컬, 인코포레이티드. |
팽창가능 의료용 디바이스
|
EP3800254A1
(en)
|
2012-06-08 |
2021-04-07 |
Ethris GmbH |
Pulmonary delivery of messenger rna
|
TWI654997B
(zh)
|
2012-06-08 |
2019-04-01 |
日商日東電工股份有限公司 |
用於治療劑輸送配方之脂質
|
EP2858679B2
(en)
|
2012-06-08 |
2024-06-05 |
Translate Bio, Inc. |
Pulmonary delivery of mrna to non-lung target cells
|
WO2014014613A2
(en)
|
2012-06-20 |
2014-01-23 |
President And Fellows Of Harvard College |
Self-assembling peptides, peptide nanostructures and uses thereof
|
US20140005379A1
(en)
|
2012-06-20 |
2014-01-02 |
Frank GU |
Nanoparticle delivery system and components thereof
|
WO2014004436A2
(en)
|
2012-06-27 |
2014-01-03 |
Merck Sharp & Dohme Corp. |
Crystalline anti-human il-23 antibodies
|
US9956291B2
(en)
|
2012-07-10 |
2018-05-01 |
Shaker A. Mousa |
Nanoformulation and methods of use of thyroid receptor beta1 agonists for liver targeting
|
WO2014014890A1
(en)
|
2012-07-16 |
2014-01-23 |
Nanoderm Sciences, Inc. |
Targeted therapeutic nanoparticles
|
EP2687251A1
(en)
|
2012-07-17 |
2014-01-22 |
Sanofi-Aventis Deutschland GmbH |
Drug delivery device
|
EP2687252A1
(en)
|
2012-07-17 |
2014-01-22 |
Sanofi-Aventis Deutschland GmbH |
Drug delivery device
|
CN112587671A
(zh)
|
2012-07-18 |
2021-04-02 |
博笛生物科技有限公司 |
癌症的靶向免疫治疗
|
WO2014015334A1
(en)
|
2012-07-20 |
2014-01-23 |
Brown University |
System and methods for nanostructure protected delivery of treatment agent and selective release thereof
|
US10604543B2
(en)
|
2012-07-24 |
2020-03-31 |
President And Fellows Of Harvard College |
Self-assembly of nucleic acid nanostructures
|
WO2014015422A1
(en)
|
2012-07-27 |
2014-01-30 |
Ontario Institute For Cancer Research |
Cellulose-based nanoparticles for drug delivery
|
GB201213624D0
(en)
|
2012-07-27 |
2012-09-12 |
Univ Ulster The |
Method and system for production of conjugated nanoparticles
|
WO2014024193A1
(en)
|
2012-08-07 |
2014-02-13 |
Prodel Pharma Ltd. |
Compositions and methods for rapid transmucosal delivery of pharmaceutical ingredients
|
WO2014025795A1
(en)
|
2012-08-07 |
2014-02-13 |
Northeastern University |
Compositions for the delivery of rna and drugs into cells
|
CN104812434A
(zh)
|
2012-08-08 |
2015-07-29 |
普莱萨格生命科学公司 |
用于药物递送的挤出方法和装置
|
US9974886B2
(en)
|
2012-08-08 |
2018-05-22 |
Nanyang Technological University |
Methods of manufacturing hydrogel microparticles having living cells, and compositions for manufacturing a scaffold for tissue engineering
|
AU2013299641A1
(en)
|
2012-08-10 |
2015-03-19 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Drug delivery vehicle comprising conjugates between targeting polyamino acids and fatty acids
|
WO2014027006A1
(en)
|
2012-08-13 |
2014-02-20 |
Edko Pazarlama Tanitim Ticaret Limited Sirketi |
Bioadhesive formulations for use in drug delivery
|
CA2884870C
(en)
|
2012-08-13 |
2022-03-29 |
Massachusetts Institute Of Technology |
Amine-containing lipidoids and uses thereof
|
WO2014026284A1
(en)
|
2012-08-14 |
2014-02-20 |
Froese Aaron |
Internal structured self assembling liposomes
|
US9827321B2
(en)
|
2012-08-14 |
2017-11-28 |
The Trustees Of The University Of Pennsylvania |
Stabilizing shear-thinning hydrogels
|
AU2013302526B2
(en)
|
2012-08-15 |
2018-03-22 |
The University Of Chicago |
Exosome-based therapeutics against neurodegenerative disorders
|
WO2014039185A1
(en)
|
2012-09-05 |
2014-03-13 |
Creighton University |
Polymeric nanoparticles in a thermosensitive gel for coital-independent vaginal prophylaxis of hiv
|
US8703197B2
(en)
|
2012-09-13 |
2014-04-22 |
International Business Machines Corporation |
Branched polyamines for delivery of biologically active materials
|
AU2013315118B2
(en)
|
2012-09-17 |
2017-10-05 |
Pfizer Inc. |
Process for preparing therapeutic nanoparticles
|
WO2014047649A1
(en)
|
2012-09-24 |
2014-03-27 |
The Regents Of The University Of California |
Methods for arranging and packing nucleic acids for unusual resistance to nucleases and targeted delivery for gene therapy
|
WO2014052634A1
(en)
|
2012-09-27 |
2014-04-03 |
The University Of North Carolina At Chapel Hill |
Lipid coated nanoparticles containing agents having low aqueous and lipid solubilities and methods thereof
|
CN104812372A
(zh)
|
2012-10-04 |
2015-07-29 |
约翰内斯堡金山大学 |
脂质体药物递送系统
|
WO2014053879A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
WO2014053881A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
US20140100178A1
(en)
|
2012-10-04 |
2014-04-10 |
Aslam Ansari |
Composition and methods for site-specific drug delivery to treat malaria and other liver diseases
|
EP2716655A1
(en)
|
2012-10-04 |
2014-04-09 |
Institut Pasteur |
Neutralizing antibodies directed against Hepatitis C virus ectodomain glycoprotein E2
|
WO2014053882A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
WO2014053880A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
EP2716689A1
(en)
|
2012-10-05 |
2014-04-09 |
National University of Ireland, Galway |
Polymer comprising a plurality of branches having at least one disulfide group and/or at least one vinyl group
|
WO2014064534A2
(en)
|
2012-10-05 |
2014-05-01 |
Chrontech Pharma Ab |
Injection needle, device, immunogenic compositions and method of use
|
US9931410B2
(en)
|
2012-10-09 |
2018-04-03 |
The Brigham And Women's Hospital, Inc. |
Nanoparticles for targeted delivery of multiple therapeutic agents and methods of use
|
US20140106260A1
(en)
|
2012-10-11 |
2014-04-17 |
The Trustees Of The University Of Pennsylvania |
Core-shell nanoparticulate compositions and methods
|
AU2013331440A1
(en)
|
2012-10-16 |
2015-04-30 |
Endocyte, Inc. |
Drug delivery conjugates containing unnatural amino acids and methods for using
|
AU2013331049B2
(en)
|
2012-10-18 |
2018-11-15 |
California Institute Of Technology |
Broadly-neutralizing anti-HIV antibodies
|
AU2013336237A1
(en)
|
2012-10-22 |
2015-06-11 |
Sabag-Rfa Ltd |
A system for delivering therapeutic agents into living cells and cells nuclei
|
WO2014066898A1
(en)
|
2012-10-26 |
2014-05-01 |
The Johns Hopkins University |
A layer-by-layer approach to co-deliver dna and sirna via aunps: a potential platform for modifying release kinetics
|
US9938525B2
(en)
|
2012-10-26 |
2018-04-10 |
Nlife Therapeutics, S.L. |
Compositions and methods for selective delivery of oligonucleotide molecules to cell types
|
US10172956B2
(en)
|
2012-10-26 |
2019-01-08 |
Vanderbilt University |
Polymeric nanoparticles
|
US20150376581A1
(en)
|
2012-10-29 |
2015-12-31 |
Technische Universitaet Dortmund |
T7 rna polymerase variants and methods of using the same
|
KR102121086B1
(ko)
|
2012-11-01 |
2020-06-09 |
팩터 바이오사이언스 인크. |
세포에서 단백질을 발현시키는 방법들과 생성물들
|
WO2014071072A2
(en)
|
2012-11-02 |
2014-05-08 |
Pungente Michael D |
Novel cationic carotenoid-based lipids for cellular nucleic acid uptake
|
EP2914723B1
(en)
|
2012-11-05 |
2018-06-13 |
Fondazione Centro San Raffaele |
Novel targets in multiple myeloma and other disorders
|
WO2014074597A1
(en)
|
2012-11-06 |
2014-05-15 |
President And Fellows Of Harvard College |
Compositions and methods relating to complex nucleic acid nanostructures
|
US8852648B2
(en)
|
2012-11-06 |
2014-10-07 |
Rochal Industries, Llp |
Delivery of biologically-active agents using volatile, hydrophobic solvents
|
US9669104B2
(en)
|
2012-11-07 |
2017-06-06 |
Council Of Scientific And Industrial Research |
Nanocomplex containing amphipathic peptide useful for efficient transfection of biomolecules
|
EP2916874B1
(en)
|
2012-11-07 |
2018-08-29 |
Council of Scientific and Industrial Research |
Nanocomplex containing cationic peptide for biomolecule delivery
|
EP2917238A1
(en)
|
2012-11-08 |
2015-09-16 |
Eleven Biotherapeutics, Inc. |
Il-6 antagonists and uses thereof
|
US20150258120A1
(en)
|
2012-11-08 |
2015-09-17 |
Clearside Biomedical, Inc. |
Methods and devices for the treatment of ocular diseases in human subjects
|
CA2890766A1
(en)
|
2012-11-08 |
2014-05-15 |
Novozymes Biopharma Dk A/S |
Albumin variants
|
TW201428101A
(zh)
|
2012-11-08 |
2014-07-16 |
Inviragen Inc |
登革熱病毒血清型4型之建構物的組成物、方法及用途
|
WO2014071963A1
(en)
|
2012-11-09 |
2014-05-15 |
Biontech Ag |
Method for cellular rna expression
|
AU2013343864B2
(en)
|
2012-11-09 |
2019-04-04 |
BioNTech SE |
Method for cellular RNA expression
|
WO2014072468A1
(en)
|
2012-11-09 |
2014-05-15 |
Velin-Pharma A/S |
Compositions for pulmonary delivery
|
US9200119B2
(en)
|
2012-11-09 |
2015-12-01 |
Momentive Performance Materials Inc. |
Silicon-containing zwitterionic linear copolymer composition
|
CN104884056A
(zh)
|
2012-11-12 |
2015-09-02 |
雷德伍德生物科技股份有限公司 |
用于制备缀合物的化合物和方法
|
EP2916862B1
(en)
|
2012-11-12 |
2020-01-08 |
GenVec, Inc. |
Malaria antigens and methods of use
|
GB201220354D0
(en)
|
2012-11-12 |
2012-12-26 |
Medpharm Ltd |
Dermal compositions
|
US9943608B2
(en)
|
2012-11-13 |
2018-04-17 |
Baylor College Of Medicine |
Multi-arm biodegradable polymers for nucleic acid delivery
|
US9310374B2
(en)
|
2012-11-16 |
2016-04-12 |
Redwood Bioscience, Inc. |
Hydrazinyl-indole compounds and methods for producing a conjugate
|
WO2014078636A1
(en)
|
2012-11-16 |
2014-05-22 |
President And Fellows Of Harvard College |
Nucleic acid hydrogel self-assembly
|
CN104853747B
(zh)
|
2012-11-19 |
2020-06-19 |
理工研究与开发基金公司 |
用于体内递送的脂质体
|
EP2732825B1
(en)
|
2012-11-19 |
2015-07-01 |
Invivogen |
Conjugates of a TLR7 and/or TLR8 agonist and a TLR2 agonist
|
WO2014081849A1
(en)
|
2012-11-20 |
2014-05-30 |
Phasebio Pharmaceuticals, Inc. |
Formulations of active agents for sustained release
|
FI2922574T3
(fi)
|
2012-11-22 |
2023-08-11 |
Tagworks Pharmaceuticals B V |
Kemiallisesti pilkkoutuva ryhmä
|
WO2014081299A1
(en)
|
2012-11-22 |
2014-05-30 |
Tagworks Pharmaceuticals B.V. |
Activatable liposomes
|
WO2014081300A1
(en)
|
2012-11-22 |
2014-05-30 |
Tagworks Pharmaceuticals B.V. |
Channel protein activatable liposomes
|
DK2922554T3
(en)
|
2012-11-26 |
2022-05-23 |
Modernatx Inc |
Terminalt modificeret rna
|
WO2014152211A1
(en)
|
2013-03-14 |
2014-09-25 |
Moderna Therapeutics, Inc. |
Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
EP4023249A1
(en)
|
2014-04-23 |
2022-07-06 |
ModernaTX, Inc. |
Nucleic acid vaccines
|