SG10201602654SA - Modified nucleosides,nucleotides,and nucleic acids,and uses thereof - Google Patents

Modified nucleosides,nucleotides,and nucleic acids,and uses thereof

Info

Publication number
SG10201602654SA
SG10201602654SA SG10201602654SA SG10201602654SA SG10201602654SA SG 10201602654S A SG10201602654S A SG 10201602654SA SG 10201602654S A SG10201602654S A SG 10201602654SA SG 10201602654S A SG10201602654S A SG 10201602654SA SG 10201602654S A SG10201602654S A SG 10201602654SA
Authority
SG
Singapore
Prior art keywords
nucleotides
uses
nucleic acids
modified nucleosides
nucleosides
Prior art date
Application number
SG10201602654SA
Inventor
De Fougerolles Antonin
Roy Atanu
P Schrum Jason
Siddiqi Suhaib
Hatala Paul
Bancel Stephane
Original Assignee
Moderna Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
Priority to US201161542533P priority Critical
Application filed by Moderna Therapeutics Inc filed Critical Moderna Therapeutics Inc
Publication of SG10201602654SA publication Critical patent/SG10201602654SA/en
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48044115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201602654S(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A61K48/0066Manipulation of the nucleic acid to modify its expression pattern, e.g. enhance its duration of expression, achieved by the presence of particular introns in the delivered nucleic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/193Colony stimulating factors [CSF]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • C07K14/535Granulocyte CSF; Granulocyte-macrophage CSF
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
SG10201602654SA 2011-10-03 2012-10-03 Modified nucleosides,nucleotides,and nucleic acids,and uses thereof SG10201602654SA (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US201161542533P true 2011-10-03 2011-10-03

Publications (1)

Publication Number Publication Date
SG10201602654SA true SG10201602654SA (en) 2016-05-30

Family

ID=48044115

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201401196WA SG11201401196WA (en) 2011-10-03 2012-10-03 Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
SG10201602654SA SG10201602654SA (en) 2011-10-03 2012-10-03 Modified nucleosides,nucleotides,and nucleic acids,and uses thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201401196WA SG11201401196WA (en) 2011-10-03 2012-10-03 Modified nucleosides, nucleotides, and nucleic acids, and uses thereof

Country Status (15)

Country Link
US (3) US9428535B2 (en)
EP (2) EP2763701B1 (en)
JP (4) JP6113737B2 (en)
KR (2) KR102014061B1 (en)
CN (2) CN103974724B (en)
AU (3) AU2012318752B2 (en)
BR (1) BR112014007852A2 (en)
CA (1) CA2850624A1 (en)
HK (1) HK1200730A1 (en)
IL (2) IL231808A (en)
MX (1) MX354267B (en)
NZ (1) NZ623476A (en)
RU (2) RU2707251C2 (en)
SG (2) SG11201401196WA (en)
WO (1) WO2013052523A1 (en)

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