JP7368856B2 - Ｔｉｍ－３とそのリガンドとの相互作用の遮断によるがん治療 - Google Patents

Ｔｉｍ－３とそのリガンドとの相互作用の遮断によるがん治療 Download PDF

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JP7368856B2
JP7368856B2 JP2020527838A JP2020527838A JP7368856B2 JP 7368856 B2 JP7368856 B2 JP 7368856B2 JP 2020527838 A JP2020527838 A JP 2020527838A JP 2020527838 A JP2020527838 A JP 2020527838A JP 7368856 B2 JP7368856 B2 JP 7368856B2
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gal3
tim
antibody
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サン，ドンフ
ワン，ヤン
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トゥルーバインディング，インコーポレイテッド
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
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JP2020527838A 2017-07-25 2018-07-24 Ｔｉｍ－３とそのリガンドとの相互作用の遮断によるがん治療 Active JP7368856B2 (ja)

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JP2023118382A JP7789386B2 (ja) 2017-07-25 2023-07-20 Ｔｉｍ－３とそのリガンドとの相互作用の遮断によるがん治療

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US201762536886P 2017-07-25 2017-07-25
US62/536,886 2017-07-25
PCT/US2018/043513 WO2019023247A1 (en) 2017-07-25 2018-07-24 TREATMENT OF CANCER BY BLOCKING THE INTERACTION OF TIM-3 AND ITS LIGAND

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US (3) US12227567B2 (enExample)
EP (1) EP3658172A4 (enExample)
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CN (1) CN111201030B (enExample)
AU (1) AU2018308088B2 (enExample)
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AU2018308088B2 (en) 2017-07-25 2025-05-29 Truebinding, Inc. Treating cancer by blocking the interaction of TIM-3 and its ligand
US12180285B2 (en) * 2018-02-01 2024-12-31 Memorial Sloan Kettering Cancer Center Antibodies to galectin-3 and methods of use thereof
JP2022523333A (ja) * 2019-01-30 2022-04-22 トゥルーバインディング，インコーポレイテッド 抗ｇａｌ３抗体およびその使用
CN115279789A (zh) * 2019-12-06 2022-11-01 真和制药有限公司 破坏gal3和胰岛素受体或整联蛋白的相互作用的抗体及其使用方法
AU2021207461A1 (en) * 2020-01-13 2022-09-01 Truebinding, Inc. Anti-Gal3 antibodies and methods of use
JP7421400B2 (ja) * 2020-03-30 2024-01-24 アークレイ株式会社 ヒトガレクチン－３の分析、検出、測定に関する抗体、方法及びキット
US12281166B2 (en) 2020-05-26 2025-04-22 Truebinding, Inc. Methods of treating inflammatory diseases by blocking Galectin-3
EP4259201A4 (en) * 2020-12-08 2025-03-19 Memorial Sloan Kettering Cancer Center Antibodies to galectin-3 and methods of use thereof
EP4326773A4 (en) 2021-04-23 2025-09-24 Suzhou Neologics Bioscience Co Ltd ANTIBODIES TARGETING TIM-3 AND THEIR USES
US20240285740A1 (en) 2021-05-12 2024-08-29 Dana-Farber Cancer Institute, Inc. Compositions and methods for treating cancer
EP4370555A4 (en) 2021-07-13 2025-11-12 Truebinding Inc METHODS FOR PREVENTING PROTEIN AGGREGATION
JP2024544508A (ja) 2021-11-09 2024-12-03 トゥルーバインディング，インコーポレイテッド 心臓血管疾患を治療または阻害する方法

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JP2012507724A (ja) 2008-10-29 2012-03-29 ビージー メディシン， インコーポレイテッド ガレクチン−３の免疫アッセイ

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