ITRM20120383A1 - Metodo e kit per la rivelazione di anticorpi. - Google Patents

Metodo e kit per la rivelazione di anticorpi.

Info

Publication number
ITRM20120383A1
ITRM20120383A1 IT000383A ITRM20120383A ITRM20120383A1 IT RM20120383 A1 ITRM20120383 A1 IT RM20120383A1 IT 000383 A IT000383 A IT 000383A IT RM20120383 A ITRM20120383 A IT RM20120383A IT RM20120383 A1 ITRM20120383 A1 IT RM20120383A1
Authority
IT
Italy
Prior art keywords
kit
detecting antibodies
antibodies
detecting
Prior art date
Application number
IT000383A
Other languages
English (en)
Inventor
Carlo Ferrarese
Fabrizio Piazza
Original Assignee
Uni Degli Studi Di Milano B Icocca
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uni Degli Studi Di Milano B Icocca filed Critical Uni Degli Studi Di Milano B Icocca
Priority to IT000383A priority Critical patent/ITRM20120383A1/it
Priority to EP13720082.0A priority patent/EP2828660B1/en
Priority to JP2015501035A priority patent/JP2015514206A/ja
Priority to ES13720082.0T priority patent/ES2664576T3/es
Priority to CA2867449A priority patent/CA2867449A1/en
Priority to US14/387,161 priority patent/US20150094218A1/en
Priority to PCT/IB2013/052206 priority patent/WO2013140349A1/en
Publication of ITRM20120383A1 publication Critical patent/ITRM20120383A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4703—Regulators; Modulating activity
    • G01N2333/4704—Inhibitors; Supressors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4709—Amyloid plaque core protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2821—Alzheimer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2871—Cerebrovascular disorders, e.g. stroke, cerebral infarct, cerebral haemorrhage, transient ischemic event
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IT000383A 2012-03-20 2012-08-02 Metodo e kit per la rivelazione di anticorpi. ITRM20120383A1 (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT000383A ITRM20120383A1 (it) 2012-03-20 2012-08-02 Metodo e kit per la rivelazione di anticorpi.
EP13720082.0A EP2828660B1 (en) 2012-03-20 2013-03-20 A method and a kit for the detection of anti-beta amyloid antibodies
JP2015501035A JP2015514206A (ja) 2012-03-20 2013-03-20 抗ベータアミロイド抗体の検出に関する方法及びキット
ES13720082.0T ES2664576T3 (es) 2012-03-20 2013-03-20 Un método y un kit para la detección de anticuerpos anti-beta-amiloides
CA2867449A CA2867449A1 (en) 2012-03-20 2013-03-20 A method and a kit for the detection of anti-beta amyloid antibodies
US14/387,161 US20150094218A1 (en) 2012-03-20 2013-03-20 Method and kit for detection of anti-beta amyloid antibodies
PCT/IB2013/052206 WO2013140349A1 (en) 2012-03-20 2013-03-20 A method and a kit for the detection of anti-beta amyloid antibodies

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITRM20120103 2012-03-20
IT000383A ITRM20120383A1 (it) 2012-03-20 2012-08-02 Metodo e kit per la rivelazione di anticorpi.

Publications (1)

Publication Number Publication Date
ITRM20120383A1 true ITRM20120383A1 (it) 2013-09-21

Family

ID=46022566

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000383A ITRM20120383A1 (it) 2012-03-20 2012-08-02 Metodo e kit per la rivelazione di anticorpi.

Country Status (7)

Country Link
US (1) US20150094218A1 (it)
EP (1) EP2828660B1 (it)
JP (1) JP2015514206A (it)
CA (1) CA2867449A1 (it)
ES (1) ES2664576T3 (it)
IT (1) ITRM20120383A1 (it)
WO (1) WO2013140349A1 (it)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20140049T1 (hr) 2007-01-05 2014-02-28 University Of Zürich Anti beta-amiloid antitijela i njihova upotreba
DK2949666T3 (en) 2008-12-19 2019-03-25 Biogen Int Neuroscience Gmbh HUMAN ANTI-ALPHA SYNUCLEIN ANTIBODIES
MX357193B (es) 2011-06-23 2018-06-29 Univ Zuerich Moleculas de union anti-alfa sinucleina.
EA201591019A1 (ru) * 2012-12-07 2015-11-30 Байоджен Интернэшнл Нейросайенз Гмбх СПОСОБ СНИЖЕНИЯ КОЛИЧЕСТВА АМИЛОИДНЫХ БЛЯШЕК В ГОЛОВНОМ МОЗГЕ ПРИ ПОМОЩИ АНТИ-Aβ АНТИТЕЛ
MA41115A (fr) 2014-12-02 2017-10-10 Biogen Int Neuroscience Gmbh Procédé de traitement de la maladie d'alzheimer
CN109655620B (zh) * 2016-03-03 2022-04-19 浙江聚康生物工程有限公司 能与β淀粉样蛋白结合的生物大分子及其编码DNA、β淀粉样蛋白检测试剂盒及其用途
CN105784689A (zh) * 2016-04-20 2016-07-20 北京中航赛维生物科技有限公司 一种抗着丝点抗体IgG的磁微粒化学发光定量测定试剂盒及制备和检测方法
CN105954267A (zh) * 2016-04-20 2016-09-21 北京中航赛维生物科技有限公司 一种抗组蛋白抗体IgG的磁微粒化学发光定量测定试剂盒及制备和检测方法
CN105954266A (zh) * 2016-04-20 2016-09-21 北京中航赛维生物科技有限公司 一种抗核糖体P蛋白抗体IgG的磁微粒化学发光定量测定试剂盒及制备和检测方法
TW201827467A (zh) 2016-11-03 2018-08-01 比利時商健生藥品公司 焦穀胺酸類澱粉蛋白－β之抗體及其用途
US12227567B2 (en) 2017-07-25 2025-02-18 Truebinding, Inc. Treating cancer by blocking the interaction of TIM-3 and its ligand
IL272773B2 (en) 2017-08-22 2024-06-01 Biogen Ma Inc Pharmaceutical compositions containing anti-beta amyloid antibodies
EP3827267A2 (en) * 2018-07-23 2021-06-02 Sorbonne Universite Methods for diagnosing a cerebral amyloid angiopathy by amyloid beta autoantibodies
CA3134785A1 (en) 2019-03-26 2020-10-01 Janssen Pharmaceutica Nv Antibodies to pyroglutamate amyloid-.beta. and uses thereof
CN111505308B (zh) * 2020-04-23 2023-05-23 西安医学院 一种基于ELISA的PirB抑制剂筛选模型及其应用
CN116157151A (zh) 2020-05-26 2023-05-23 真和制药有限公司 通过阻断半乳凝素-3治疗炎性疾病的方法
CN116348487A (zh) 2020-07-23 2023-06-27 欧萨尔普罗席纳有限公司 抗淀粉样β抗体
CN116643055A (zh) * 2023-06-05 2023-08-25 深圳市天大生物医疗器械有限公司 一种人β淀粉样蛋白Aβ1-42检测试剂盒

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010128139A1 (en) * 2009-05-08 2010-11-11 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin Biomarkers and methods for diagnosing alzheimer's disease and/ or mild cognitive impairment
DE102009034119A1 (de) 2009-07-20 2011-01-27 Philipps-Universität Marburg Verfahren, insbesondere Enzyme-linked Immunosorbent Assay (ELISA), zum in vitro Nachweis von Amyloid beta Autoantikörpern, Mikrotiterplatte und Testkit
CA2774134A1 (en) * 2009-09-18 2011-03-24 Probiodrug Ag Novel assay for the detection of amyloid beta peptides
JP5488885B2 (ja) * 2009-10-28 2014-05-14 国立大学法人 東京大学 感染症の疾患マーカー

Also Published As

Publication number Publication date
EP2828660B1 (en) 2017-12-06
ES2664576T3 (es) 2018-04-20
EP2828660A1 (en) 2015-01-28
JP2015514206A (ja) 2015-05-18
US20150094218A1 (en) 2015-04-02
CA2867449A1 (en) 2013-09-26
WO2013140349A1 (en) 2013-09-26

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