PL4094754T3 - Kompozycje do leczenia chorób związanych z agregacją białek i/lub zapobiegania takim chorobom - Google Patents

Kompozycje do leczenia chorób związanych z agregacją białek i/lub zapobiegania takim chorobom

Info

Publication number
PL4094754T3
PL4094754T3 PL22186334.3T PL22186334T PL4094754T3 PL 4094754 T3 PL4094754 T3 PL 4094754T3 PL 22186334 T PL22186334 T PL 22186334T PL 4094754 T3 PL4094754 T3 PL 4094754T3
Authority
PL
Poland
Prior art keywords
compositions
treatment
diseases related
protein aggregation
preventing diseases
Prior art date
Application number
PL22186334.3T
Other languages
English (en)
Inventor
Manuel J. MUÑOZ
Ángel M. CARRIÓN
Mercedes M. PÉREZ-JIMÉNEZ
Original Assignee
Universidad Pablo De Olavide
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad Pablo De Olavide filed Critical Universidad Pablo De Olavide
Publication of PL4094754T3 publication Critical patent/PL4094754T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37Coumarins, e.g. psoralen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
PL22186334.3T 2018-06-19 2019-06-19 Kompozycje do leczenia chorób związanych z agregacją białek i/lub zapobiegania takim chorobom PL4094754T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP18382439 2018-06-19

Publications (1)

Publication Number Publication Date
PL4094754T3 true PL4094754T3 (pl) 2026-01-05

Family

ID=62716030

Family Applications (2)

Application Number Title Priority Date Filing Date
PL22186334.3T PL4094754T3 (pl) 2018-06-19 2019-06-19 Kompozycje do leczenia chorób związanych z agregacją białek i/lub zapobiegania takim chorobom
PL19730826.5T PL3810128T3 (pl) 2018-06-19 2019-06-19 Kompozycje do leczenia i/lub zapobiegania chorobom związanym z agregacją białek

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL19730826.5T PL3810128T3 (pl) 2018-06-19 2019-06-19 Kompozycje do leczenia i/lub zapobiegania chorobom związanym z agregacją białek

Country Status (16)

Country Link
US (1) US20210251953A1 (pl)
EP (2) EP3810128B1 (pl)
JP (2) JP2021528442A (pl)
CN (2) CN118845759A (pl)
AU (1) AU2019291061B2 (pl)
BR (1) BR112020026066A2 (pl)
CA (1) CA3103834A1 (pl)
DK (1) DK3810128T3 (pl)
ES (2) ES3044215T3 (pl)
HR (1) HRP20251214T1 (pl)
MX (1) MX2020014070A (pl)
PL (2) PL4094754T3 (pl)
PT (1) PT3810128T (pl)
RS (1) RS67299B1 (pl)
SM (1) SMT202500382T1 (pl)
WO (1) WO2019243453A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3070446A1 (en) 2017-07-25 2019-01-31 Immutics, Inc. Treating cancer by blocking the interaction of tim-3 and its ligand
PL4094754T3 (pl) * 2018-06-19 2026-01-05 Universidad Pablo De Olavide Kompozycje do leczenia chorób związanych z agregacją białek i/lub zapobiegania takim chorobom
CN120058944A (zh) 2019-01-30 2025-05-30 真和制药有限公司 抗gal3抗体及其用途
EP4157338A4 (en) 2020-05-26 2024-11-13 TrueBinding, Inc. METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING
EP3988096A1 (en) 2020-10-26 2022-04-27 Universidad Pablo de Olavide OTRI Sulfated c19 steroid hormones to treat and/or prevent proteotoxicity in protein-aggregation diseases
CN112552272B (zh) * 2020-12-22 2023-06-27 四川大学 香豆素类化合物及其制备方法和应用、药物组合物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9603325D0 (en) 1996-02-16 1996-04-17 Imperial College A compound
US5556847A (en) * 1994-10-27 1996-09-17 Duquesne University Of The Holy Ghost Methods of effecting memory enhancement mediated by steroid sulfatase inhibitors
JP4320089B2 (ja) * 1999-07-06 2009-08-26 あすか製薬株式会社 フェニルスルファメート誘導体
DE60124730T2 (de) * 2000-03-03 2007-10-04 Eisai R&D Management Co., Ltd. Neue methoden unter verwendung von cholinesteraseinhibitoren
US20060183776A9 (en) * 2000-03-03 2006-08-17 Eisai Co., Ltd. Liquid dosage formulations of donepezil
GB0511190D0 (en) * 2005-06-01 2005-07-06 Sterix Ltd Use
ES2514140B1 (es) 2013-03-26 2015-08-03 Universidad Pablo De Olavide Uso del inhibidor de sulfatasas esteroideas STX64 para el tratamiento del envejecimiento
MX2017007095A (es) * 2014-12-05 2017-11-17 An2H Discovery Ltd Metodos y composiciones de activacion de la ligasa parkin.
MX2018005352A (es) 2015-10-30 2018-08-14 Ultragenyx Pharmaceutical Inc Metodos y composiciones para el tratamiento de amiloidosis.
US10780094B2 (en) * 2016-07-22 2020-09-22 New York University Use of carbonic anhydrase inhibitors for treatment of neurological and psychiatric disorders
PL4094754T3 (pl) * 2018-06-19 2026-01-05 Universidad Pablo De Olavide Kompozycje do leczenia chorób związanych z agregacją białek i/lub zapobiegania takim chorobom

Also Published As

Publication number Publication date
HRP20251214T1 (hr) 2025-12-19
EP4094754C0 (en) 2025-08-06
MX2020014070A (es) 2021-05-27
PL3810128T3 (pl) 2023-01-30
BR112020026066A2 (pt) 2021-03-23
PT3810128T (pt) 2022-11-09
EP3810128B1 (en) 2022-08-03
AU2019291061A1 (en) 2021-02-04
RS67299B1 (sr) 2025-11-28
EP4094754B1 (en) 2025-08-06
CN112601521A (zh) 2021-04-02
US20210251953A1 (en) 2021-08-19
ES2931815T3 (es) 2023-01-02
CN118845759A (zh) 2024-10-29
JP2021528442A (ja) 2021-10-21
DK3810128T3 (da) 2022-10-31
EP3810128A1 (en) 2021-04-28
AU2019291061B2 (en) 2025-04-10
CA3103834A1 (en) 2019-12-26
JP2024059803A (ja) 2024-05-01
ES3044215T3 (en) 2025-11-26
SMT202500382T1 (it) 2025-11-10
EP4094754A1 (en) 2022-11-30
WO2019243453A1 (en) 2019-12-26

Similar Documents

Publication Publication Date Title
PL4094754T3 (pl) Kompozycje do leczenia chorób związanych z agregacją białek i/lub zapobiegania takim chorobom
IL280710A (en) Methods and compositions for treating mitochondrial disease or disorders and heteroplasmy
IL283042A (en) Compounds and compositions for treating conditions associated with nlrp activity
PL3717471T3 (pl) Nowe związki i zawierające je kompozycje farmaceutyczne do leczenia chorób
PL3661954T3 (pl) Muteiny interleukiny 21 i sposoby leczenia
EP3349783C0 (en) COMPOSITIONS AND METHODS ASSOCIATED WITH THE TREATMENT OF DISEASES
IL268850A (en) Combinations of a 4-pyrimidinesulfamide derivative with active ingredients for the treatment of endothelin related diseases
EP3263132C0 (en) Composition for treating il-6-related diseases
SI3377637T1 (sl) Sestavki za uporabo pri postopkih za zdravljenje ran, motenj in bolezni kože
CL2018001652A1 (es) Composiciones y métodos para disminuir la expresión de tau
EP3784260A4 (en) Compositions for the treatment of skin conditions
PL3484469T3 (pl) Kompozycje i sposoby do wzmacniania działania środków przeciwdrobnoustrojowych
EP3914231A4 (en) Treatment of skin disorders with topical tapinarof combination compositions
PL3381451T3 (pl) Kompozycja farmaceutyczna stosowana do redukcji zlokalizowanej tkanki tłuszczowej i zastosowanie kompozycji farmaceutycznej
EP3790563A4 (en) Compositions for the treatment of skin conditions
IL269158A (en) Compositions and methods for treating inflammatory diseases
IL281938A (en) Stable semaglutide compositions and uses thereof
EP3600285A4 (en) TOPICAL COMPOSITIONS AND METHODS OF TREATMENT
EP3541401A4 (en) TREATMENT OF RESPIRATORY TRACT INFECTIONS AND DISEASES WITH GLUTATHION COMPOSITIONS
EP3582768A4 (en) CANNABINOID FORMULATIONS FOR THE TREATMENT OF DERMATITIS AND INFLAMMATORY SKIN DISEASES
EP3398437A4 (en) PESTICIDE COMPOSITION CONTAINING METCONAZOLE FOR PREVENTING AND TREATING FUSARIOSIS OF PPE AND ITS APPLICATION
IL269550A (en) Compositions and methods for treating synucleinopathies
EP3592377A4 (en) TISSUE KALLICREIN DOSAGE FORMS 1
EP3775261A4 (en) TARGET BOND FRACTION COMPOSITIONS AND METHODS OF USE
EP3347034A4 (en) COMPOSITIONS AND METHODS OF PREVENTING AND TREATING HORN SKIN AND SCARCING