DK3810128T3 - Sammensætninger til behandling og/eller forebyggelse af proteinaggregeringssygdomme - Google Patents

Sammensætninger til behandling og/eller forebyggelse af proteinaggregeringssygdomme Download PDF

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Publication number
DK3810128T3
DK3810128T3 DK19730826.5T DK19730826T DK3810128T3 DK 3810128 T3 DK3810128 T3 DK 3810128T3 DK 19730826 T DK19730826 T DK 19730826T DK 3810128 T3 DK3810128 T3 DK 3810128T3
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DK
Denmark
Prior art keywords
prevention
compositions
treatment
protein aggregation
aggregation diseases
Prior art date
Application number
DK19730826.5T
Other languages
English (en)
Inventor
Mercedes M Pérez-Jiménez
Manuel J Muñoz
Ángel M Carrión
Original Assignee
Univ Pablo De Olavide
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Univ Pablo De Olavide filed Critical Univ Pablo De Olavide
Application granted granted Critical
Publication of DK3810128T3 publication Critical patent/DK3810128T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37Coumarins, e.g. psoralen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
DK19730826.5T 2018-06-19 2019-06-19 Sammensætninger til behandling og/eller forebyggelse af proteinaggregeringssygdomme DK3810128T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18382439 2018-06-19
PCT/EP2019/066271 WO2019243453A1 (en) 2018-06-19 2019-06-19 Compositions for treating and/or preventing protein-aggregation diseases

Publications (1)

Publication Number Publication Date
DK3810128T3 true DK3810128T3 (da) 2022-10-31

Family

ID=62716030

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19730826.5T DK3810128T3 (da) 2018-06-19 2019-06-19 Sammensætninger til behandling og/eller forebyggelse af proteinaggregeringssygdomme

Country Status (13)

Country Link
US (1) US20210251953A1 (da)
EP (2) EP3810128B1 (da)
JP (2) JP2021528442A (da)
CN (1) CN112601521A (da)
AU (1) AU2019291061A1 (da)
BR (1) BR112020026066A2 (da)
CA (1) CA3103834A1 (da)
DK (1) DK3810128T3 (da)
ES (1) ES2931815T3 (da)
MX (1) MX2020014070A (da)
PL (1) PL3810128T3 (da)
PT (1) PT3810128T (da)
WO (1) WO2019243453A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3988096A1 (en) 2020-10-26 2022-04-27 Universidad Pablo de Olavide OTRI Sulfated c19 steroid hormones to treat and/or prevent proteotoxicity in protein-aggregation diseases
CN112552272B (zh) * 2020-12-22 2023-06-27 四川大学 香豆素类化合物及其制备方法和应用、药物组合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9603325D0 (en) 1996-02-16 1996-04-17 Imperial College A compound
US5556847A (en) * 1994-10-27 1996-09-17 Duquesne University Of The Holy Ghost Methods of effecting memory enhancement mediated by steroid sulfatase inhibitors
JP4320089B2 (ja) * 1999-07-06 2009-08-26 あすか製薬株式会社 フェニルスルファメート誘導体
EP2140868A1 (en) * 2000-03-03 2010-01-06 Eisai R&D Management Co., Ltd. Use of a cholinesterase inhibitor for the treatment of dementia and cognitive impairments associated with or caused by chemotherapy
US20060183776A9 (en) * 2000-03-03 2006-08-17 Eisai Co., Ltd. Liquid dosage formulations of donepezil
GB0511190D0 (en) * 2005-06-01 2005-07-06 Sterix Ltd Use
ES2514140B1 (es) * 2013-03-26 2015-08-03 Universidad Pablo De Olavide Uso del inhibidor de sulfatasas esteroideas STX64 para el tratamiento del envejecimiento
KR20170092634A (ko) * 2014-12-05 2017-08-11 에이엔2에이치 디스커버리 리미티드 파킨 리가제 활성화 방법 및 조성물
MX2018005352A (es) 2015-10-30 2018-08-14 Ultragenyx Pharmaceutical Inc Metodos y composiciones para el tratamiento de amiloidosis.
US10780094B2 (en) * 2016-07-22 2020-09-22 New York University Use of carbonic anhydrase inhibitors for treatment of neurological and psychiatric disorders

Also Published As

Publication number Publication date
JP2021528442A (ja) 2021-10-21
PT3810128T (pt) 2022-11-09
US20210251953A1 (en) 2021-08-19
WO2019243453A1 (en) 2019-12-26
AU2019291061A1 (en) 2021-02-04
JP2024059803A (ja) 2024-05-01
PL3810128T3 (pl) 2023-01-30
EP3810128A1 (en) 2021-04-28
CN112601521A (zh) 2021-04-02
BR112020026066A2 (pt) 2021-03-23
EP3810128B1 (en) 2022-08-03
ES2931815T3 (es) 2023-01-02
MX2020014070A (es) 2021-05-27
EP4094754A1 (en) 2022-11-30
CA3103834A1 (en) 2019-12-26

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