DK3277270T3 - Sammensætninger og fremgangsmåder til behandling af anæmi - Google Patents

Sammensætninger og fremgangsmåder til behandling af anæmi Download PDF

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Publication number
DK3277270T3
DK3277270T3 DK16774184.2T DK16774184T DK3277270T3 DK 3277270 T3 DK3277270 T3 DK 3277270T3 DK 16774184 T DK16774184 T DK 16774184T DK 3277270 T3 DK3277270 T3 DK 3277270T3
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Denmark
Prior art keywords
anemia
procedures
compositions
treatment
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DK16774184.2T
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English (en)
Inventor
Ramin Farzaneh-Far
Alexander Smith
Gurudatt Ajay Chandorkar
Ene Ikpong Ette
Bradley John Maroni
Charlotte Suzanne Hartman
Jula Kern Inrig
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Akebia Therapeutics Inc
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Publication of DK3277270T3 publication Critical patent/DK3277270T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
DK16774184.2T 2015-04-01 2016-03-31 Sammensætninger og fremgangsmåder til behandling af anæmi DK3277270T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562141420P 2015-04-01 2015-04-01
US201562270168P 2015-12-21 2015-12-21
PCT/US2016/025235 WO2016161094A1 (en) 2015-04-01 2016-03-31 Compositions and methods for treating anemia

Publications (1)

Publication Number Publication Date
DK3277270T3 true DK3277270T3 (da) 2021-12-06

Family

ID=57006457

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16774184.2T DK3277270T3 (da) 2015-04-01 2016-03-31 Sammensætninger og fremgangsmåder til behandling af anæmi

Country Status (37)

Country Link
US (2) US11324734B2 (da)
EP (2) EP3995138A1 (da)
JP (3) JP6929785B2 (da)
KR (2) KR20240038132A (da)
CN (2) CN107645953B (da)
AU (3) AU2016243700B2 (da)
BR (1) BR112017021097B1 (da)
CA (1) CA2981176A1 (da)
CL (2) CL2017002456A1 (da)
CO (1) CO2017011200A2 (da)
CR (2) CR20170450A (da)
CU (1) CU20170126A7 (da)
CY (1) CY1124869T1 (da)
DK (1) DK3277270T3 (da)
EA (1) EA036920B1 (da)
EC (1) ECSP17073209A (da)
ES (1) ES2900481T3 (da)
HK (1) HK1248590A1 (da)
HR (1) HRP20211862T1 (da)
HU (1) HUE056958T2 (da)
IL (3) IL292262B2 (da)
LT (1) LT3277270T (da)
MA (1) MA41863A (da)
MX (3) MX2017012460A (da)
MY (1) MY192705A (da)
NZ (1) NZ735973A (da)
PE (1) PE20180189A1 (da)
PH (1) PH12017501789A1 (da)
PL (1) PL3277270T3 (da)
PT (1) PT3277270T (da)
SA (1) SA517390054B1 (da)
SG (1) SG11201707994UA (da)
SI (1) SI3277270T1 (da)
TW (2) TWI794725B (da)
UA (1) UA123308C2 (da)
WO (1) WO2016161094A1 (da)
ZA (2) ZA201706681B (da)

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NO2686520T3 (da) 2011-06-06 2018-03-17
LT3007695T (lt) 2013-06-13 2024-03-25 Akebia Therapeutics, Inc. Kompozicijos ir būdai, skirti anemijos gydymui
JP2016537365A (ja) 2013-11-15 2016-12-01 アケビア セラピューティクス インコーポレイテッドAkebia Therapeutics Inc. {[5−(3−クロロフェニル)−3−ヒドロキシピリジン−2−カルボニル]アミノ}酢酸の固体形態、組成物、及びその使用
TW201632504A (zh) 2015-01-23 2016-09-16 阿克比治療有限公司 2-(5-(3-氟苯基)-3-羥吡啶醯胺基)乙酸之固體形式、其組合物及其用途
CR20170450A (es) * 2015-04-01 2018-04-03 Akebia Therapeutics Inc Composiciones y métodos para el tratamiento de la anemia
JP6864834B2 (ja) * 2017-06-14 2021-04-28 ニプロ株式会社 投与量決定プログラムおよび投与量決定装置
WO2019028150A1 (en) 2017-08-01 2019-02-07 Akebia Therapeutics, Inc. COMPOSITIONS FOR USE IN METHODS OF TREATING HEMOGLOBINOPATHIES
CA3097219A1 (en) 2018-05-09 2019-11-14 Akebia Therapeutics, Inc. Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid
JP2023501221A (ja) 2019-10-31 2023-01-18 アケビア セラピューティクス インコーポレイテッド バダデュスタットを使用する治療方法
US11524939B2 (en) 2019-11-13 2022-12-13 Akebia Therapeutics, Inc. Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid
AU2021263829A1 (en) * 2020-04-29 2022-12-15 BioAge Labs, Inc. Hypoxia-inducible factor prolyl hydroxylase inhibitors for treating aging-related conditions
JP2023530452A (ja) 2020-06-19 2023-07-18 アケビア セラピューティクス インコーポレイテッド バダデュスタットの薬物間相互作用の調節
IL303961A (en) 2021-01-08 2023-08-01 Akebia Therapeutics Inc Therapeutic methods using VADADUSTAT
WO2022150623A1 (en) 2021-01-08 2022-07-14 Akebia Therapeutics, Inc. Compounds and composition for the treatment of anemia
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