MX2017012460A - Composiciones y metodos para el tratamiento de la anemia. - Google Patents
Composiciones y metodos para el tratamiento de la anemia.Info
- Publication number
- MX2017012460A MX2017012460A MX2017012460A MX2017012460A MX2017012460A MX 2017012460 A MX2017012460 A MX 2017012460A MX 2017012460 A MX2017012460 A MX 2017012460A MX 2017012460 A MX2017012460 A MX 2017012460A MX 2017012460 A MX2017012460 A MX 2017012460A
- Authority
- MX
- Mexico
- Prior art keywords
- anemia
- compositions
- methods
- treating anemia
- kidney disease
- Prior art date
Links
- 208000007502 anemia Diseases 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 title 1
- 208000020832 chronic kidney disease Diseases 0.000 abstract 2
- 208000030507 AIDS Diseases 0.000 abstract 1
- 229940113151 HIF prolyl hydroxylase inhibitor Drugs 0.000 abstract 1
- 238000002512 chemotherapy Methods 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 238000000502 dialysis Methods 0.000 abstract 1
- YOZBGTLTNGAVFU-UHFFFAOYSA-N roxadustat Chemical compound C1=C2C(C)=NC(C(=O)NCC(O)=O)=C(O)C2=CC=C1OC1=CC=CC=C1 YOZBGTLTNGAVFU-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
Abstract
Dosis específicas de y regímenes de dosificación para, por el uso de un inhibidor de prolil hidroxilasa de HIF en el tratamiento o la prevención de la anemia, tal como la anemia secundaria a o asociada con la enfermedad renal crónica, la anemia secundaria a o asociada con la enfermedad renal crónica no dependiente de diálisis, la anemia asociada o que resulta de la quimioterapia o la anemia asociada con el SIDA.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562141420P | 2015-04-01 | 2015-04-01 | |
US201562270168P | 2015-12-21 | 2015-12-21 | |
PCT/US2016/025235 WO2016161094A1 (en) | 2015-04-01 | 2016-03-31 | Compositions and methods for treating anemia |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2017012460A true MX2017012460A (es) | 2018-01-30 |
Family
ID=57006457
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017012460A MX2017012460A (es) | 2015-04-01 | 2016-03-31 | Composiciones y metodos para el tratamiento de la anemia. |
MX2020009415A MX2020009415A (es) | 2015-04-01 | 2016-03-31 | El uso del inhibidor de propil hidrolasa del factor inducible de hipoxia (hif) para el tratamiento o prevencion de la anemia. |
MX2021012155A MX2021012155A (es) | 2015-04-01 | 2017-09-28 | Composiciones y metodos para el tratamiento de la anemia. |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020009415A MX2020009415A (es) | 2015-04-01 | 2016-03-31 | El uso del inhibidor de propil hidrolasa del factor inducible de hipoxia (hif) para el tratamiento o prevencion de la anemia. |
MX2021012155A MX2021012155A (es) | 2015-04-01 | 2017-09-28 | Composiciones y metodos para el tratamiento de la anemia. |
Country Status (37)
Country | Link |
---|---|
US (2) | US11324734B2 (es) |
EP (2) | EP3995138A1 (es) |
JP (3) | JP6929785B2 (es) |
KR (2) | KR102647879B1 (es) |
CN (2) | CN107645953B (es) |
AU (3) | AU2016243700B2 (es) |
BR (1) | BR112017021097B1 (es) |
CA (1) | CA2981176A1 (es) |
CL (2) | CL2017002456A1 (es) |
CO (1) | CO2017011200A2 (es) |
CR (2) | CR20210248A (es) |
CU (1) | CU20170126A7 (es) |
CY (1) | CY1124869T1 (es) |
DK (1) | DK3277270T3 (es) |
EA (1) | EA036920B1 (es) |
EC (1) | ECSP17073209A (es) |
ES (1) | ES2900481T3 (es) |
HK (1) | HK1248590A1 (es) |
HR (1) | HRP20211862T1 (es) |
HU (1) | HUE056958T2 (es) |
IL (3) | IL292262B2 (es) |
LT (1) | LT3277270T (es) |
MA (1) | MA41863A (es) |
MX (3) | MX2017012460A (es) |
MY (1) | MY192705A (es) |
NZ (1) | NZ735973A (es) |
PE (1) | PE20180189A1 (es) |
PH (1) | PH12017501789A1 (es) |
PL (1) | PL3277270T3 (es) |
PT (1) | PT3277270T (es) |
SA (1) | SA517390054B1 (es) |
SG (1) | SG11201707994UA (es) |
SI (1) | SI3277270T1 (es) |
TW (2) | TWI718138B (es) |
UA (1) | UA123308C2 (es) |
WO (1) | WO2016161094A1 (es) |
ZA (2) | ZA201706681B (es) |
Families Citing this family (16)
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LT3357911T (lt) | 2006-06-26 | 2022-08-10 | Akebia Therapeutics Inc. | Prolilo hidroksilazės inhibitoriai ir naudojimo būdai |
NO2686520T3 (es) | 2011-06-06 | 2018-03-17 | ||
BR112015031027A2 (pt) | 2013-06-13 | 2017-08-29 | Akebia Therapeutics Inc | Uso de um composto, método in vitro, composição farmacêutica e forma de dosagem única |
SG10202012791TA (en) | 2013-11-15 | 2021-01-28 | Akebia Therapeutics Inc | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof |
JP2018502882A (ja) | 2015-01-23 | 2018-02-01 | アケビア セラピューティクス インコーポレイテッドAkebia Therapeutics Inc. | 2−(5−(3−フルオロフェニル)−3−ヒドロキシピコリンアミド)酢酸の固体形態、その組成物及び使用 |
MX2017012460A (es) * | 2015-04-01 | 2018-01-30 | Akebia Therapeutics Inc | Composiciones y metodos para el tratamiento de la anemia. |
JP6864834B2 (ja) * | 2017-06-14 | 2021-04-28 | ニプロ株式会社 | 投与量決定プログラムおよび投与量決定装置 |
WO2019028150A1 (en) | 2017-08-01 | 2019-02-07 | Akebia Therapeutics, Inc. | COMPOSITIONS FOR USE IN METHODS OF TREATING HEMOGLOBINOPATHIES |
EP3790863A1 (en) | 2018-05-09 | 2021-03-17 | Akebia Therapeutics Inc. | Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid |
AU2020374963A1 (en) | 2019-10-31 | 2022-06-09 | Akebia Therapeutics, Inc. | Therapeutic methods using vadadustat |
US11524939B2 (en) | 2019-11-13 | 2022-12-13 | Akebia Therapeutics, Inc. | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid |
CA3181403A1 (en) * | 2020-04-29 | 2021-11-04 | BioAge Labs, Inc. | Hypoxia-inducible factor prolyl hydroxylase inhibitors for treating aging-related conditions |
KR20230027157A (ko) | 2020-06-19 | 2023-02-27 | 아케비아 테라퓨틱스 인코포레이티드 | 바다두스타트의 약물-약물 상호작용의 조절 |
WO2022150623A1 (en) | 2021-01-08 | 2022-07-14 | Akebia Therapeutics, Inc. | Compounds and composition for the treatment of anemia |
JP2024503377A (ja) | 2021-01-08 | 2024-01-25 | アケビア セラピューティクス インコーポレイテッド | バダデュスタットを使用した治療方法 |
KR20230152078A (ko) | 2021-03-01 | 2023-11-02 | 아케비아 테라퓨틱스 인코포레이티드 | 바다두스타트의 약물-약물 상호작용의 조절 |
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