DK3319609T3 - Sammensætninger og fremgangsmåder til anvendelse af antibakterielle lægemiddelkombinationer - Google Patents

Sammensætninger og fremgangsmåder til anvendelse af antibakterielle lægemiddelkombinationer Download PDF

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Publication number
DK3319609T3
DK3319609T3 DK16822054.9T DK16822054T DK3319609T3 DK 3319609 T3 DK3319609 T3 DK 3319609T3 DK 16822054 T DK16822054 T DK 16822054T DK 3319609 T3 DK3319609 T3 DK 3319609T3
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DK
Denmark
Prior art keywords
compositions
methods
drug combinations
antibacterial drug
antibacterial
Prior art date
Application number
DK16822054.9T
Other languages
English (en)
Inventor
Gautam Dantas
Patrick Gonzales
Kevin Forsberg
Mitchell Pesesky
Mayland Chang
Shahriar Mobashery
Original Assignee
Univ Washington
Univ Notre Dame Du Lac
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington, Univ Notre Dame Du Lac filed Critical Univ Washington
Application granted granted Critical
Publication of DK3319609T3 publication Critical patent/DK3319609T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/424Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A61K31/431Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
DK16822054.9T 2015-07-09 2016-07-08 Sammensætninger og fremgangsmåder til anvendelse af antibakterielle lægemiddelkombinationer DK3319609T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562190588P 2015-07-09 2015-07-09
PCT/US2016/041565 WO2017008034A1 (en) 2015-07-09 2016-07-08 Compositions and methods of use of antibacterial drug combinations

Publications (1)

Publication Number Publication Date
DK3319609T3 true DK3319609T3 (da) 2022-08-22

Family

ID=57686086

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16822054.9T DK3319609T3 (da) 2015-07-09 2016-07-08 Sammensætninger og fremgangsmåder til anvendelse af antibakterielle lægemiddelkombinationer

Country Status (10)

Country Link
US (3) US10500191B2 (da)
EP (2) EP4112057A1 (da)
JP (3) JP6845511B2 (da)
CN (2) CN108289896B (da)
DK (1) DK3319609T3 (da)
ES (1) ES2929058T3 (da)
HK (1) HK1258393A1 (da)
PL (1) PL3319609T3 (da)
PT (1) PT3319609T (da)
WO (1) WO2017008034A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6845511B2 (ja) 2015-07-09 2021-03-17 ワシントン・ユニバーシティWashington University 抗細菌性薬剤併用物の組成物及び使用方法
CN107789355B (zh) * 2016-09-07 2022-04-12 湘北威尔曼制药股份有限公司 含有哌拉西林的复方药物组合物及其应用
US10434089B2 (en) 2017-01-25 2019-10-08 The Johns Hopkins University Avibactam and carbapenems antibacterial agents
US11690810B2 (en) * 2018-11-14 2023-07-04 The Chinese University Of Hong Kong Combination treatment of bacterial infection
CN110279692A (zh) * 2019-07-17 2019-09-27 中南大学湘雅二医院 一种抗感染组合物、制剂及其应用
GB202100378D0 (en) * 2021-01-12 2021-02-24 Quadram Inst Bioscience Methods and compositions for antibiotic potentiation
CN113559099A (zh) * 2021-08-27 2021-10-29 丹诺医药(苏州)有限公司 包含舒巴坦和阿维巴坦的药物组合物及其应用
CN117940127A (zh) * 2022-07-05 2024-04-26 塞戈瑞·弗拉基米罗维奇·西多连科 治疗多种耐药细菌感染的制剂
CN115778949A (zh) * 2022-12-15 2023-03-14 复旦大学附属华山医院 用于抑制产kpc酶肺炎克雷伯菌的组合物、药物及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1565456A (zh) * 2003-06-14 2005-01-19 张哲峰 一种头孢吡肟抗菌组合药物
EP2167081B1 (en) * 2007-05-21 2013-06-26 Hans Rudolf Pfaendler Bactericidal anti-mrsa active pharmaceutical composition containing carbapenems
US20100197650A1 (en) * 2008-08-28 2010-08-05 Forest Laboratories Holdings Ltd. Compositions and methods of treatment comprising ceftaroline
CN102349897B (zh) * 2011-07-22 2012-12-26 深圳市新泰医药有限公司 一种美罗培南钠/他唑巴坦钠药物组合物
EP2768503A1 (en) 2011-07-26 2014-08-27 Wockhardt Limited Pharmaceutical compositions comprising beta-lactam antibiotic, sulbactam and beta-lactamase inhibitor
WO2013085152A1 (en) * 2011-12-07 2013-06-13 Union Korea Pharm Co., Ltd. Combined antibiotics comprising cephalosporins and beta-lactamase inhibitors
NZ706734A (en) 2012-09-03 2016-05-27 Wockhardt Ltd Pharmaceutical compositions useful for the treatment or control of bacterial infections
GB201306980D0 (en) * 2013-04-17 2013-05-29 Blueberry Therapeutics Ltd Methods
CA2983992A1 (en) 2015-04-30 2016-11-03 The Regents Of The University Of Colorado, A Body Corporate Polycyclic indoline and indolenine compounds
JP6845511B2 (ja) 2015-07-09 2021-03-17 ワシントン・ユニバーシティWashington University 抗細菌性薬剤併用物の組成物及び使用方法
WO2017203266A1 (en) 2016-05-25 2017-11-30 Entasis Therapeutics Limited Combination therapy for treatment of resistant bacterial infections

Also Published As

Publication number Publication date
ES2929058T3 (es) 2022-11-24
CN108289896B (zh) 2022-03-01
JP7121954B2 (ja) 2022-08-19
US11559514B2 (en) 2023-01-24
JP2021075560A (ja) 2021-05-20
PT3319609T (pt) 2022-08-23
JP2022141948A (ja) 2022-09-29
JP2018525434A (ja) 2018-09-06
US20180200226A1 (en) 2018-07-19
EP4112057A1 (en) 2023-01-04
CN114796499A (zh) 2022-07-29
PL3319609T3 (pl) 2022-12-05
EP3319609A1 (en) 2018-05-16
JP6845511B2 (ja) 2021-03-17
US20200054605A1 (en) 2020-02-20
WO2017008034A1 (en) 2017-01-12
US10500191B2 (en) 2019-12-10
EP3319609A4 (en) 2018-12-12
US20230293488A1 (en) 2023-09-21
HK1258393A1 (zh) 2019-11-08
EP3319609B1 (en) 2022-06-15
CN108289896A (zh) 2018-07-17

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