PT3319609T - Composições e métodos de uso de combinações de fármacos antibacterianos - Google Patents

Composições e métodos de uso de combinações de fármacos antibacterianos

Info

Publication number
PT3319609T
PT3319609T PT168220549T PT16822054T PT3319609T PT 3319609 T PT3319609 T PT 3319609T PT 168220549 T PT168220549 T PT 168220549T PT 16822054 T PT16822054 T PT 16822054T PT 3319609 T PT3319609 T PT 3319609T
Authority
PT
Portugal
Prior art keywords
compositions
methods
drug combinations
antibacterial drug
antibacterial
Prior art date
Application number
PT168220549T
Other languages
English (en)
Original Assignee
Univ Washington
Univ Notre Dame Du Lac
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington, Univ Notre Dame Du Lac filed Critical Univ Washington
Publication of PT3319609T publication Critical patent/PT3319609T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT168220549T 2015-07-09 2016-07-08 Composições e métodos de uso de combinações de fármacos antibacterianos PT3319609T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562190588P 2015-07-09 2015-07-09

Publications (1)

Publication Number Publication Date
PT3319609T true PT3319609T (pt) 2022-08-23

Family

ID=57686086

Family Applications (1)

Application Number Title Priority Date Filing Date
PT168220549T PT3319609T (pt) 2015-07-09 2016-07-08 Composições e métodos de uso de combinações de fármacos antibacterianos

Country Status (10)

Country Link
US (3) US10500191B2 (pt)
EP (2) EP3319609B1 (pt)
JP (3) JP6845511B2 (pt)
CN (2) CN108289896B (pt)
DK (1) DK3319609T3 (pt)
ES (1) ES2929058T3 (pt)
HK (1) HK1258393A1 (pt)
PL (1) PL3319609T3 (pt)
PT (1) PT3319609T (pt)
WO (1) WO2017008034A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108289896B (zh) 2015-07-09 2022-03-01 华盛顿大学 抗菌药物组合的组合物和使用方法
CN107789355B (zh) * 2016-09-07 2022-04-12 湘北威尔曼制药股份有限公司 含有哌拉西林的复方药物组合物及其应用
US10434089B2 (en) 2017-01-25 2019-10-08 The Johns Hopkins University Avibactam and carbapenems antibacterial agents
US11690810B2 (en) * 2018-11-14 2023-07-04 The Chinese University Of Hong Kong Combination treatment of bacterial infection
CN110279692A (zh) * 2019-07-17 2019-09-27 中南大学湘雅二医院 一种抗感染组合物、制剂及其应用
GB202100378D0 (en) * 2021-01-12 2021-02-24 Quadram Inst Bioscience Methods and compositions for antibiotic potentiation
CN113559099A (zh) * 2021-08-27 2021-10-29 丹诺医药(苏州）有限公司 包含舒巴坦和阿维巴坦的药物组合物及其应用
CN117940127A (zh) * 2022-07-05 2024-04-26 塞戈瑞·弗拉基米罗维奇·西多连科 治疗多种耐药细菌感染的制剂
CN115778949A (zh) * 2022-12-15 2023-03-14 复旦大学附属华山医院 用于抑制产kpc酶肺炎克雷伯菌的组合物、药物及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1565456A (zh) * 2003-06-14 2005-01-19 张哲峰 一种头孢吡肟抗菌组合药物
WO2008141764A1 (en) * 2007-05-21 2008-11-27 Hans Rudolf Pfaendler Bactericidal anti-mrsa active pharmaceutical composition containing carbapenems
MX2011002185A (es) * 2008-08-28 2011-04-04 Astrazeneca Ab Composiciones y metodos de tratamiento que comprenden ceftarolina.
CN102349897B (zh) * 2011-07-22 2012-12-26 深圳市新泰医药有限公司 一种美罗培南钠/他唑巴坦钠药物组合物
WO2013014497A1 (en) 2011-07-26 2013-01-31 Wockhardt Limited Pharmaceutical compositions comprising beta-lactam antibiotic, sulbactam and beta-lactamase inhibitor
WO2013085152A1 (en) * 2011-12-07 2013-06-13 Union Korea Pharm Co., Ltd. Combined antibiotics comprising cephalosporins and beta-lactamase inhibitors
US20150258072A1 (en) 2012-09-03 2015-09-17 Wockhardt Limited Antibacterial compositions
GB201306980D0 (en) * 2013-04-17 2013-05-29 Blueberry Therapeutics Ltd Methods
US10253024B2 (en) * 2015-04-30 2019-04-09 The Regents Of The University Of Colorado, A Body Corporate Polycyclic indoline and indolenine compounds
CN108289896B (zh) 2015-07-09 2022-03-01 华盛顿大学 抗菌药物组合的组合物和使用方法
WO2017203266A1 (en) * 2016-05-25 2017-11-30 Entasis Therapeutics Limited Combination therapy for treatment of resistant bacterial infections

Also Published As

Publication number Publication date
EP3319609A4 (en) 2018-12-12
HK1258393A1 (zh) 2019-11-08
CN108289896B (zh) 2022-03-01
EP4112057A1 (en) 2023-01-04
US10500191B2 (en) 2019-12-10
CN108289896A (zh) 2018-07-17
WO2017008034A1 (en) 2017-01-12
JP7121954B2 (ja) 2022-08-19
DK3319609T3 (da) 2022-08-22
JP2021075560A (ja) 2021-05-20
CN114796499A (zh) 2022-07-29
ES2929058T3 (es) 2022-11-24
PL3319609T3 (pl) 2022-12-05
JP2022141948A (ja) 2022-09-29
JP6845511B2 (ja) 2021-03-17
EP3319609B1 (en) 2022-06-15
EP3319609A1 (en) 2018-05-16
US20180200226A1 (en) 2018-07-19
JP2018525434A (ja) 2018-09-06
US11559514B2 (en) 2023-01-24
US20230293488A1 (en) 2023-09-21
US20200054605A1 (en) 2020-02-20

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