DK3759083T3 - 2,4-diaminoquinazolinderivater og anvendelse deraf til behandling af virusinfektioner, cancer eller allergier - Google Patents

2,4-diaminoquinazolinderivater og anvendelse deraf til behandling af virusinfektioner, cancer eller allergier Download PDF

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Publication number
DK3759083T3
DK3759083T3 DK19708817.2T DK19708817T DK3759083T3 DK 3759083 T3 DK3759083 T3 DK 3759083T3 DK 19708817 T DK19708817 T DK 19708817T DK 3759083 T3 DK3759083 T3 DK 3759083T3
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Denmark
Prior art keywords
allergies
cancer
treatment
virus infections
diaminoquinazoline derivatives
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Application number
DK19708817.2T
Other languages
English (en)
Inventor
Gowan David Craig Mc
Werner Constant Johan Embrechts
Ludwig Paul Cooymans
Tim Hugo Maria Jonckers
Pierre Jean-Marie Bernard Raboisson
Jérôme Émile Georges Guillemont
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Janssen Sciences Ireland Unlimited Co
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Publication of DK3759083T3 publication Critical patent/DK3759083T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
DK19708817.2T 2018-03-01 2019-02-28 2,4-diaminoquinazolinderivater og anvendelse deraf til behandling af virusinfektioner, cancer eller allergier DK3759083T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18159583 2018-03-01
PCT/EP2019/054941 WO2019166532A1 (en) 2018-03-01 2019-02-28 2,4-diaminoquinazoline derivatives and medical uses thereof

Publications (1)

Publication Number Publication Date
DK3759083T3 true DK3759083T3 (da) 2022-08-01

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DK19708817.2T DK3759083T3 (da) 2018-03-01 2019-02-28 2,4-diaminoquinazolinderivater og anvendelse deraf til behandling af virusinfektioner, cancer eller allergier

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Country Link
US (2) US11597704B2 (da)
EP (2) EP3759083B1 (da)
JP (1) JP2021514981A (da)
KR (1) KR20200128394A (da)
CN (1) CN111868040A (da)
AR (1) AR114420A1 (da)
AU (1) AU2019226342B2 (da)
BR (1) BR112020017702A2 (da)
CA (1) CA3091076A1 (da)
CL (3) CL2020002253A1 (da)
DK (1) DK3759083T3 (da)
EA (1) EA202092052A1 (da)
ES (1) ES2923579T3 (da)
HR (1) HRP20220781T1 (da)
HU (1) HUE059149T2 (da)
IL (2) IL305388A (da)
JO (1) JOP20200208A1 (da)
LT (1) LT3759083T (da)
MA (1) MA52411B1 (da)
MD (1) MD3759083T2 (da)
MX (2) MX2020009071A (da)
PH (1) PH12020551345A1 (da)
PL (1) PL3759083T3 (da)
PT (1) PT3759083T (da)
RS (1) RS63401B1 (da)
SG (1) SG11202008293YA (da)
SI (1) SI3759083T1 (da)
TW (1) TW201945003A (da)
UA (1) UA127590C2 (da)
WO (1) WO2019166532A1 (da)

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UA127590C2 (uk) 2023-10-25
AR114420A1 (es) 2020-09-02
MA52411A (fr) 2021-01-06
CL2021001753A1 (es) 2021-12-17
PT3759083T (pt) 2022-07-05
PH12020551345A1 (en) 2021-09-06
EP4059924A1 (en) 2022-09-21
EA202092052A1 (ru) 2020-12-07
JP2021514981A (ja) 2021-06-17
IL305388A (en) 2023-10-01
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KR20200128394A (ko) 2020-11-12
BR112020017702A2 (pt) 2020-12-22
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CL2020002253A1 (es) 2021-01-15
EP3759083B1 (en) 2022-05-04
MX2020009071A (es) 2020-10-08
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WO2019166532A1 (en) 2019-09-06
IL276952A (en) 2020-10-29
CL2022000125A1 (es) 2022-10-07
ES2923579T3 (es) 2022-09-28
CA3091076A1 (en) 2019-09-06
IL276952B2 (en) 2024-02-01
HUE059149T2 (hu) 2022-10-28
EP3759083A1 (en) 2021-01-06
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SI3759083T1 (sl) 2022-08-31
LT3759083T (lt) 2022-07-11
PL3759083T3 (pl) 2022-08-29
MA52411B1 (fr) 2022-12-30
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