SG11202008293YA - 2,4-diaminoquinazoline derivatives and medical uses thereof - Google Patents

2,4-diaminoquinazoline derivatives and medical uses thereof

Info

Publication number
SG11202008293YA
SG11202008293YA SG11202008293YA SG11202008293YA SG11202008293YA SG 11202008293Y A SG11202008293Y A SG 11202008293YA SG 11202008293Y A SG11202008293Y A SG 11202008293YA SG 11202008293Y A SG11202008293Y A SG 11202008293YA SG 11202008293Y A SG11202008293Y A SG 11202008293YA
Authority
SG
Singapore
Prior art keywords
medical uses
diaminoquinazoline derivatives
diaminoquinazoline
derivatives
medical
Prior art date
Application number
SG11202008293YA
Inventor
Gowan David Mc
Werner EMBRECHTS
Jérôme Guillemont
Ludwig Cooymans
Tim Jonckers
Pierre Raboisson
Original Assignee
Janssen Sciences Ireland Unlimited Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Sciences Ireland Unlimited Co filed Critical Janssen Sciences Ireland Unlimited Co
Publication of SG11202008293YA publication Critical patent/SG11202008293YA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
SG11202008293YA 2018-03-01 2019-02-28 2,4-diaminoquinazoline derivatives and medical uses thereof SG11202008293YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18159583 2018-03-01
PCT/EP2019/054941 WO2019166532A1 (en) 2018-03-01 2019-02-28 2,4-diaminoquinazoline derivatives and medical uses thereof

Publications (1)

Publication Number Publication Date
SG11202008293YA true SG11202008293YA (en) 2020-09-29

Family

ID=61557126

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202008293YA SG11202008293YA (en) 2018-03-01 2019-02-28 2,4-diaminoquinazoline derivatives and medical uses thereof

Country Status (30)

Country Link
US (2) US11597704B2 (en)
EP (2) EP4059924A1 (en)
JP (1) JP2021514981A (en)
KR (1) KR20200128394A (en)
CN (1) CN111868040A (en)
AR (1) AR114420A1 (en)
AU (1) AU2019226342B2 (en)
BR (1) BR112020017702A2 (en)
CA (1) CA3091076A1 (en)
CL (3) CL2020002253A1 (en)
DK (1) DK3759083T3 (en)
EA (1) EA202092052A1 (en)
ES (1) ES2923579T3 (en)
HR (1) HRP20220781T1 (en)
HU (1) HUE059149T2 (en)
IL (2) IL276952B2 (en)
JO (1) JOP20200208A1 (en)
LT (1) LT3759083T (en)
MA (1) MA52411B1 (en)
MD (1) MD3759083T2 (en)
MX (2) MX2020009071A (en)
PH (1) PH12020551345A1 (en)
PL (1) PL3759083T3 (en)
PT (1) PT3759083T (en)
RS (1) RS63401B1 (en)
SG (1) SG11202008293YA (en)
SI (1) SI3759083T1 (en)
TW (1) TW201945003A (en)
UA (1) UA127590C2 (en)
WO (1) WO2019166532A1 (en)

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AU2016306275A1 (en) 2015-08-07 2018-02-08 Arrowhead Pharmaceuticals, Inc. RNAi therapy for Hepatitis B virus infection
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JP7373571B2 (en) 2019-01-14 2023-11-02 イネイト・テューマー・イミュニティ・インコーポレイテッド Substituted quinazolines as NLRP3 modulators for use in cancer therapy
CA3140707A1 (en) * 2019-06-18 2020-12-24 Helen Horton Combination of hepatitis b virus (hbv) vaccines and quinazoline derivatives
AU2020333708C1 (en) * 2019-08-19 2024-02-22 Shanghai Zhimeng Biopharma Inc. 2-aminopyrimidine compounds and pharmaceutical compositions and uses thereof
WO2021114691A1 (en) * 2019-12-13 2021-06-17 四川科伦博泰生物医药股份有限公司 Nitrogen-containing ring-fused compound, preparation method therefor and use thereof
KR20220123437A (en) * 2020-01-02 2022-09-06 지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 Crystalline form of pyridopyrimidine derivative and method for preparing same

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Publication number Publication date
WO2019166532A1 (en) 2019-09-06
PT3759083T (en) 2022-07-05
BR112020017702A2 (en) 2020-12-22
MA52411B1 (en) 2022-12-30
LT3759083T (en) 2022-07-11
IL305388A (en) 2023-10-01
US20210040046A1 (en) 2021-02-11
KR20200128394A (en) 2020-11-12
CA3091076A1 (en) 2019-09-06
TW201945003A (en) 2019-12-01
PL3759083T3 (en) 2022-08-29
MA52411A (en) 2021-01-06
CN111868040A (en) 2020-10-30
AU2019226342A1 (en) 2020-08-13
IL276952A (en) 2020-10-29
PH12020551345A1 (en) 2021-09-06
JP2021514981A (en) 2021-06-17
JOP20200208A1 (en) 2020-08-30
DK3759083T3 (en) 2022-08-01
RS63401B1 (en) 2022-08-31
ES2923579T3 (en) 2022-09-28
MX2023001803A (en) 2023-03-10
US20230278964A1 (en) 2023-09-07
MX2020009071A (en) 2020-10-08
AU2019226342B2 (en) 2024-02-15
SI3759083T1 (en) 2022-08-31
EP4059924A1 (en) 2022-09-21
UA127590C2 (en) 2023-10-25
MD3759083T2 (en) 2022-09-30
EP3759083B1 (en) 2022-05-04
HUE059149T2 (en) 2022-10-28
IL276952B1 (en) 2023-10-01
CL2020002253A1 (en) 2021-01-15
IL276952B2 (en) 2024-02-01
EA202092052A1 (en) 2020-12-07
HRP20220781T1 (en) 2022-09-30
CL2022000125A1 (en) 2022-10-07
US11597704B2 (en) 2023-03-07
CL2021001753A1 (en) 2021-12-17
AR114420A1 (en) 2020-09-02
EP3759083A1 (en) 2021-01-06

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