CL2021001753A1 - Compuestos derivados de 2,4-diaminoquinazolina; composición farmacéutica; y su uso para el tratamiento de una infección vírica, cáncer, entre otras (divisional de solicitud 202002253). - Google Patents
Compuestos derivados de 2,4-diaminoquinazolina; composición farmacéutica; y su uso para el tratamiento de una infección vírica, cáncer, entre otras (divisional de solicitud 202002253).Info
- Publication number
- CL2021001753A1 CL2021001753A1 CL2021001753A CL2021001753A CL2021001753A1 CL 2021001753 A1 CL2021001753 A1 CL 2021001753A1 CL 2021001753 A CL2021001753 A CL 2021001753A CL 2021001753 A CL2021001753 A CL 2021001753A CL 2021001753 A1 CL2021001753 A1 CL 2021001753A1
- Authority
- CL
- Chile
- Prior art keywords
- diaminoquinazoline
- cancer
- treatment
- pharmaceutical composition
- viral infection
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 208000036142 Viral infection Diseases 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- XELRMPRLCPFTBH-UHFFFAOYSA-N quinazoline-2,4-diamine Chemical compound C1=CC=CC2=NC(N)=NC(N)=C21 XELRMPRLCPFTBH-UHFFFAOYSA-N 0.000 title abstract 2
- 230000009385 viral infection Effects 0.000 title abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Abstract
COMPUESTOS DERIVADOS DE 2,4-DIAMINOQUINAZOLINA; COMPOSICIÓN FARMACÉUTICA QUE LOS COMPRENDE; Y SU USO PARA EL TRATAMIENTO DE UNA INFECCIÓN VÍRICA, CÁNCER, ENTRE OTRAS (DIVISIONAL DE SOLICITUD 202002253).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP18159583 | 2018-03-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2021001753A1 true CL2021001753A1 (es) | 2021-12-17 |
Family
ID=61557126
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2020002253A CL2020002253A1 (es) | 2018-03-01 | 2020-08-31 | Derivados de 2,4 - diaminoquinazolina y usos médicos de los mismos. |
CL2021001753A CL2021001753A1 (es) | 2018-03-01 | 2021-06-30 | Compuestos derivados de 2,4-diaminoquinazolina; composición farmacéutica; y su uso para el tratamiento de una infección vírica, cáncer, entre otras (divisional de solicitud 202002253). |
CL2022000125A CL2022000125A1 (es) | 2018-03-01 | 2022-01-18 | Derivados de 2,4-diaminoquinazolina y usos médicos de los mismos. (divisional de solicitud 202002253) |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2020002253A CL2020002253A1 (es) | 2018-03-01 | 2020-08-31 | Derivados de 2,4 - diaminoquinazolina y usos médicos de los mismos. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2022000125A CL2022000125A1 (es) | 2018-03-01 | 2022-01-18 | Derivados de 2,4-diaminoquinazolina y usos médicos de los mismos. (divisional de solicitud 202002253) |
Country Status (30)
Country | Link |
---|---|
US (2) | US11597704B2 (es) |
EP (2) | EP4059924A1 (es) |
JP (1) | JP2021514981A (es) |
KR (1) | KR20200128394A (es) |
CN (1) | CN111868040A (es) |
AR (1) | AR114420A1 (es) |
AU (1) | AU2019226342B2 (es) |
BR (1) | BR112020017702A2 (es) |
CA (1) | CA3091076A1 (es) |
CL (3) | CL2020002253A1 (es) |
DK (1) | DK3759083T3 (es) |
EA (1) | EA202092052A1 (es) |
ES (1) | ES2923579T3 (es) |
HR (1) | HRP20220781T1 (es) |
HU (1) | HUE059149T2 (es) |
IL (2) | IL276952B2 (es) |
JO (1) | JOP20200208A1 (es) |
LT (1) | LT3759083T (es) |
MA (1) | MA52411B1 (es) |
MD (1) | MD3759083T2 (es) |
MX (2) | MX2020009071A (es) |
PH (1) | PH12020551345A1 (es) |
PL (1) | PL3759083T3 (es) |
PT (1) | PT3759083T (es) |
RS (1) | RS63401B1 (es) |
SG (1) | SG11202008293YA (es) |
SI (1) | SI3759083T1 (es) |
TW (1) | TW201945003A (es) |
UA (1) | UA127590C2 (es) |
WO (1) | WO2019166532A1 (es) |
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JOP20170161A1 (ar) | 2016-08-04 | 2019-01-30 | Arrowhead Pharmaceuticals Inc | عوامل RNAi للعدوى بفيروس التهاب الكبد ب |
WO2020150113A1 (en) * | 2019-01-14 | 2020-07-23 | Innate Tumor Immunity, Inc. | Substituted quinazolines as nlrp3 modulators, for use in the treatment of cancer |
US20220241402A1 (en) * | 2019-06-18 | 2022-08-04 | Janssen Sciences Ireland Unlimited Company | Combination of hepatitis b virus (hbv) vaccines and quinazoline derivatives |
JP2022545872A (ja) * | 2019-08-19 | 2022-11-01 | シャンハイ ジムン バイオファーマ,インコーポレーテッド | 2―アミノピリミジン化合物ならびにその医薬組成物および用途 |
WO2021114691A1 (zh) * | 2019-12-13 | 2021-06-17 | 四川科伦博泰生物医药股份有限公司 | 含氮并环化合物、其制备方法及用途 |
WO2021136488A1 (zh) * | 2020-01-02 | 2021-07-08 | 江苏恒瑞医药股份有限公司 | 一种吡啶并嘧啶类衍生物的结晶形式及其制备方法 |
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EA202090547A3 (ru) | 2013-03-29 | 2020-12-30 | Янссен Сайенсиз Айрлэнд Юси | Макроциклические деаза-оксипурины для лечения вирусных инфекций |
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PT3097102T (pt) | 2015-03-04 | 2018-01-22 | Gilead Sciences Inc | Compostos de 4,6-diamino-pirido[3,2-d]pirimidina que modulam recetor do tipo toll |
AR107633A1 (es) | 2016-02-19 | 2018-05-16 | Hoffmann La Roche | Procedimiento para la preparación del ácido 4-fenil-5-alcoxicarbonil-2-tiazol-2-il-1,4-dihidropirimidin-6-il-[metil]-3-oxo-5,6,8,8a-tetrahidro-1h-imidazo[1,5a]pirazin-2-il-carboxílico |
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CN109476675B (zh) | 2016-07-01 | 2022-12-09 | 爱尔兰詹森科学公司 | 用于治疗病毒性感染的二氢吡喃并嘧啶衍生物 |
AU2017318601B2 (en) | 2016-09-02 | 2020-09-03 | Gilead Sciences, Inc. | Toll like receptor modulator compounds |
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