JP2013521325A5 - - Google Patents

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JP2013521325A5
JP2013521325A5 JP2012556515A JP2012556515A JP2013521325A5 JP 2013521325 A5 JP2013521325 A5 JP 2013521325A5 JP 2012556515 A JP2012556515 A JP 2012556515A JP 2012556515 A JP2012556515 A JP 2012556515A JP 2013521325 A5 JP2013521325 A5 JP 2013521325A5
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JP
Japan
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alkyl
cycloalkyl
phenyl
substituted
compound
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JP2012556515A
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Japanese (ja)
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JP2013521325A (ja
JP5688745B2 (ja
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Priority claimed from PCT/EP2011/053576 external-priority patent/WO2011110613A1/en
Publication of JP2013521325A publication Critical patent/JP2013521325A/ja
Publication of JP2013521325A5 publication Critical patent/JP2013521325A5/ja
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Publication of JP5688745B2 publication Critical patent/JP5688745B2/ja
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JP2012556515A 2010-03-10 2011-03-10 グルタミニルシクラーゼ（ｑｃ、ｅｃ２．３．２．５）の複素環阻害剤 Active JP5688745B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31233910P 2010-03-10 2010-03-10
US61/312,339 2010-03-10
PCT/EP2011/053576 WO2011110613A1 (en) 2010-03-10 2011-03-10 Heterocyclic inhibitors of glutaminyl cyclase (qc, ec 2.3.2.5)

Publications (3)

Publication Number Publication Date
JP2013521325A JP2013521325A (ja) 2013-06-10
JP2013521325A5 true JP2013521325A5 (OSRAM) 2014-04-24
JP5688745B2 JP5688745B2 (ja) 2015-03-25

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Family Applications (1)

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JP2012556515A Active JP5688745B2 (ja) 2010-03-10 2011-03-10 グルタミニルシクラーゼ（ｑｃ、ｅｃ２．３．２．５）の複素環阻害剤

Country Status (16)

Country Link
US (2) US8269019B2 (OSRAM)
EP (1) EP2545047B9 (OSRAM)
JP (1) JP5688745B2 (OSRAM)
KR (1) KR101790806B1 (OSRAM)
CN (1) CN102791704B (OSRAM)
AU (1) AU2011226074B2 (OSRAM)
BR (1) BR112012022478B1 (OSRAM)
CA (1) CA2789440C (OSRAM)
DK (1) DK2545047T3 (OSRAM)
EA (1) EA022420B1 (OSRAM)
ES (1) ES2481823T3 (OSRAM)
IL (1) IL221243A (OSRAM)
MX (1) MX2012010470A (OSRAM)
NZ (1) NZ602312A (OSRAM)
SG (1) SG183229A1 (OSRAM)
WO (1) WO2011110613A1 (OSRAM)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101790806B1 (ko) * 2010-03-10 2017-11-20 프로비오드룩 아게 글루타미닐 사이클라제(ｑｃ, ｅｃ 2.3.2.5)의 헤테로사이클릭 억제제
WO2012123563A1 (en) * 2011-03-16 2012-09-20 Probiodrug Ag Benz imidazole derivatives as inhibitors of glutaminyl cyclase
SG194770A1 (en) * 2011-05-27 2013-12-30 Probiodrug Ag Radiolabelled glutaminyl cyclase inhibitors
GB201308217D0 (en) 2013-05-08 2013-06-12 Ucl Business Plc Compounds and their use in therapy
US20170363645A1 (en) 2014-12-19 2017-12-21 Probiodrug Ag Novel Method for the Detection of pGlu-Abeta Peptides
DE102015011780A1 (de) 2015-09-16 2017-03-16 Hochschule Anhalt Neue Glutaminylcyclase-lnhibitoren
US10381473B2 (en) 2016-12-02 2019-08-13 Vishay-Siliconix High-electron-mobility transistor with buried interconnect
GB201705263D0 (en) * 2017-03-31 2017-05-17 Probiodrug Ag Novel inhibitors
RU2662559C1 (ru) * 2017-10-27 2018-07-26 Общество С Ограниченной Ответственностью "Фарминтерпрайсез" Новый ингибитор глутаминилциклаз и его применение для лечения заболеваний легких и дыхательных путей
DK3461819T3 (da) 2017-09-29 2020-08-10 Probiodrug Ag Inhibitorer af glutaminylcyklase
EP3521308B1 (en) 2018-01-31 2024-03-13 Vivoryon Therapeutics N.V. Humanized and de-immunized antibodies
JP7301862B2 (ja) * 2018-02-23 2023-07-03 フラウンホーファー－ゲゼルシャフト ツル フェルデルング デル アンゲヴァンテン フォルシュング エー ファウ 歯周病及び関連疾患の治療に用いる細菌性グルタミニルシクラーゼの新規阻害剤
EP3543231A1 (en) * 2018-03-19 2019-09-25 ETH Zurich Compounds for treating cns- and neurodegenerative diseases
US10693288B2 (en) 2018-06-26 2020-06-23 Vishay SIliconix, LLC Protection circuits with negative gate swing capability
US10833063B2 (en) 2018-07-25 2020-11-10 Vishay SIliconix, LLC High electron mobility transistor ESD protection structures
TWI715156B (zh) 2018-08-31 2021-01-01 財團法人國家衛生研究院 苯并咪唑化合物及其用於治療阿茲海默症或亨丁頓氏症之用途
SG11202101274XA (en) * 2018-08-31 2021-03-30 National Health Res Inst Benzimidazole compounds and use thereof for treating alzheimer's disease or huntington's disease

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