|
HRPK20110926B3
(hr)
|
2001-02-24 |
2013-05-31 |
Boehringer Ingelheim Pharma Gmbh & Co.Kg. |
Derivati ksantina, njihova proizvodnja i upotreba kao lijekova
|
|
WO2003002531A2
(en)
|
2001-06-27 |
2003-01-09 |
Smithkline Beecham Corporation |
Fluoropyrrolidines as dipeptidyl peptidase inhibitors
|
|
EP1338595B1
(de)
|
2002-02-25 |
2006-05-03 |
Eisai Co., Ltd. |
Xanthin-Derivate als DPP-IV-Inhibitoren
|
|
US20060100199A1
(en)
|
2002-06-06 |
2006-05-11 |
Seiji Yoshikawa |
Novel condensed imidazole derivatives
|
|
EP1521584A1
(de)
|
2002-06-17 |
2005-04-13 |
Glaxo Group Limited |
Purin-derivate als leber x-rezeptor-agonisten
|
|
US7105526B2
(en)
|
2002-06-28 |
2006-09-12 |
Banyu Pharmaceuticals Co., Ltd. |
Benzimidazole derivatives
|
|
CN100522962C
(zh)
*
|
2002-08-21 |
2009-08-05 |
贝林格尔英格海姆法玛两合公司 |
8-[3-氨基-哌啶-1-基]-黄嘌呤,其制备方法及作为药物制剂的用途
|
|
US7407955B2
(en)
|
2002-08-21 |
2008-08-05 |
Boehringer Ingelheim Pharma Gmbh & Co., Kg |
8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
|
|
US7569574B2
(en)
|
2002-08-22 |
2009-08-04 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Purine derivatives, the preparation thereof and their use as pharmaceutical compositions
|
|
US7495005B2
(en)
|
2002-08-22 |
2009-02-24 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Xanthine derivatives, their preparation and their use in pharmaceutical compositions
|
|
DE10238470A1
(de)
*
|
2002-08-22 |
2004-03-04 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
CA2498423A1
(en)
*
|
2002-09-26 |
2004-04-08 |
Eisai Co., Ltd. |
Combination drug
|
|
AU2003280680A1
(en)
*
|
2002-11-01 |
2004-06-18 |
Sumitomo Pharmaceuticals Co., Ltd. |
Xanthine compound
|
|
US7482337B2
(en)
|
2002-11-08 |
2009-01-27 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
|
|
DE10254304A1
(de)
*
|
2002-11-21 |
2004-06-03 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
|
US20040242568A1
(en)
|
2003-03-25 |
2004-12-02 |
Syrrx, Inc. |
Dipeptidyl peptidase inhibitors
|
|
WO2004096806A1
(ja)
*
|
2003-04-30 |
2004-11-11 |
Sumitomo Pharmaceuticals Co. Ltd. |
縮合イミダゾール誘導体
|
|
KR20110059664A
(ko)
|
2003-05-05 |
2011-06-02 |
프로비오드룩 아게 |
글루타미닐 및 글루타메이트 사이클라제의 이펙터의 용도
|
|
NZ543146A
(en)
|
2003-05-05 |
2008-09-26 |
Probiodrug Ag |
Use of effectors of glutaminyl cyclase (QC) activity in combination with inhibitors of DP IV or DP IV-like enzymes for the treatment of conditions that can be treated by modulation of QC-and/or DPIV-activity
|
|
WO2004098591A2
(en)
|
2003-05-05 |
2004-11-18 |
Probiodrug Ag |
Inhibitors of glutaminyl cyclase and their use in the treatment of neurological diseases
|
|
EP1625122A1
(de)
|
2003-05-14 |
2006-02-15 |
Takeda San Diego, Inc. |
Dipeptidylpeptidase-hemmer
|
|
AU2003902828A0
(en)
*
|
2003-06-05 |
2003-06-26 |
Fujisawa Pharmaceutical Co., Ltd. |
Dpp-iv inhibitor
|
|
US7566707B2
(en)
|
2003-06-18 |
2009-07-28 |
Boehringer Ingelheim International Gmbh |
Imidazopyridazinone and imidazopyridone derivatives, the preparation thereof and their use as pharmaceutical compositions
|
|
BRPI0413452A
(pt)
|
2003-08-13 |
2006-10-17 |
Takeda Pharmaceutical |
composto, composição farmacêutica, kit, artigo de fabricação, e, métodos de inibir dpp-iv, terapêutico e de tratar um estado de doença, cáncer, distúrbios autoimunes, uma condição einfecção por hiv
|
|
CA2551037A1
(en)
|
2003-09-22 |
2005-03-31 |
Banyu Pharmaceutical Co., Ltd. |
Novel piperidine derivative
|
|
CA2542419C
(en)
|
2003-10-15 |
2013-06-04 |
Probiodrug Ag |
Use of glutamyl cyclase inhibitors in the treatment of familial british dementia and familial danish dementia
|
|
ZA200603165B
(en)
|
2003-11-03 |
2007-07-25 |
Probiodrug Ag |
Combinations useful for the treatment of neuronal disorders
|
|
KR20150028829A
(ko)
|
2003-11-17 |
2015-03-16 |
노파르티스 아게 |
디펩티딜 펩티다제 ⅳ 억제제의 용도
|
|
WO2005051949A1
(ja)
*
|
2003-11-26 |
2005-06-09 |
Dainippon Sumitomo Pharma Co., Ltd. |
新規縮合イミダゾール誘導体
|
|
DE10355304A1
(de)
*
|
2003-11-27 |
2005-06-23 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue 8-(Piperazin-1-yl)-und 8-([1,4]Diazepan-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
WO2005053695A1
(ja)
*
|
2003-12-04 |
2005-06-16 |
Eisai Co., Ltd. |
多発性硬化症予防剤または治療剤
|
|
KR101259645B1
(ko)
|
2004-01-20 |
2013-04-30 |
노파르티스 아게 |
직접 압축 제제 및 방법
|
|
AU2005210004B2
(en)
|
2004-02-05 |
2010-10-28 |
Probiodrug Ag |
Novel inhibitors of glutaminyl cyclase
|
|
HRP20120006T1
(hr)
|
2004-02-05 |
2012-01-31 |
Kyorin Pharmaceutical Co. |
Derivat bicikloestera
|
|
ATE430150T1
(de)
*
|
2004-02-18 |
2009-05-15 |
Boehringer Ingelheim Int |
8-ä3-amino-piperidin-1-ylü-xanthine, deren herstellung und deren verwendung als dpp-iv hemmer
|
|
US7501426B2
(en)
|
2004-02-18 |
2009-03-10 |
Boehringer Ingelheim International Gmbh |
8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
|
|
DE102004009039A1
(de)
|
2004-02-23 |
2005-09-08 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
8-[3-Amino-piperidin-1-yl]-xanthine, deren Herstellung und Verwendung als Arzneimittel
|
|
US7393847B2
(en)
|
2004-03-13 |
2008-07-01 |
Boehringer Ingleheim International Gmbh |
Imidazopyridazinediones, their preparation and their use as pharmaceutical compositions
|
|
CN1938286A
(zh)
|
2004-03-29 |
2007-03-28 |
默克公司 |
作为11-β-羟甾类脱氢酶-1抑制剂的二芳基三唑
|
|
WO2005097127A2
(en)
|
2004-04-02 |
2005-10-20 |
Merck & Co., Inc. |
Method of treating men with metabolic and anthropometric disorders
|
|
US7439370B2
(en)
|
2004-05-10 |
2008-10-21 |
Boehringer Ingelheim International Gmbh |
Imidazole derivatives, their preparation and their use as intermediates for the preparation of pharmaceutical compositions and pesticides
|
|
DE102004030502A1
(de)
|
2004-06-24 |
2006-01-12 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Imidazole und Triazole, deren Herstellung und Verwendung als Arzneimittel
|
|
EP1797034B1
(de)
|
2004-08-06 |
2010-06-30 |
Merck Sharp & Dohme Corp. |
Sulfonylverbindungen als hemmer von 11-beta-hydroxysteroiddehydrogenase-1
|
|
DE102004043944A1
(de)
|
2004-09-11 |
2006-03-30 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue 8-(3-Amino-piperidin-1-yl)-7-(but-2-inyl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
DE102004044221A1
(de)
|
2004-09-14 |
2006-03-16 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue 3-Methyl-7-butinyl-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
WO2006039325A2
(en)
|
2004-10-01 |
2006-04-13 |
Merck & Co., Inc. |
Aminopiperidines as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
|
DE102004054054A1
(de)
|
2004-11-05 |
2006-05-11 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
|
|
JPWO2006068163A1
(ja)
*
|
2004-12-24 |
2008-06-12 |
大日本住友製薬株式会社 |
二環性ピロール誘導体
|
|
DOP2006000008A
(es)
|
2005-01-10 |
2006-08-31 |
Arena Pharm Inc |
Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1
|
|
CA2609388C
(en)
|
2005-05-30 |
2013-08-06 |
Banyu Pharmaceutical Co., Ltd. |
Novel piperidine derivative
|
|
MY152185A
(en)
|
2005-06-10 |
2014-08-29 |
Novartis Ag |
Modified release 1-[(3-hydroxy-adamant-1-ylamino)-acetyl]-pyrrolidine-2(s)-carbonitrile formulation
|
|
DE102005035891A1
(de)
|
2005-07-30 |
2007-02-08 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
GB0516462D0
(en)
*
|
2005-08-10 |
2005-09-14 |
Smithkline Beecham Corp |
Novel compounds
|
|
MX2008001929A
(es)
*
|
2005-08-10 |
2008-03-24 |
Smithkline Beecham Corp |
Derivados de xantina como agonistas de hm74a selectivos.
|
|
US20100216758A1
(en)
|
2005-08-10 |
2010-08-26 |
Makoto Ando |
Pyridone Compounds
|
|
GB0516464D0
(en)
*
|
2005-08-10 |
2005-09-14 |
Smithkline Beecham Corp |
Novel compounds
|
|
DE602006017712D1
(de)
|
2005-08-24 |
2010-12-02 |
Banyu Pharma Co Ltd |
Phenylpyridonderivat
|
|
EP1939194A4
(de)
|
2005-09-07 |
2010-12-08 |
Banyu Pharma Co Ltd |
Bicyclisches aromatisches substituiertes pyridon-derivat
|
|
SI1942898T2
(sl)
|
2005-09-14 |
2014-08-29 |
Takeda Pharmaceutical Company Limited |
Dipeptidil-peptidazni inhibitorji za zdravljenje diabetesa
|
|
CA2622642C
(en)
|
2005-09-16 |
2013-12-31 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
|
KR20080048502A
(ko)
|
2005-09-29 |
2008-06-02 |
머크 앤드 캄파니 인코포레이티드 |
멜라노코르틴-4 수용체 조절제로서의 아실화스피로피페리딘 유도체
|
|
EP1944301A4
(de)
|
2005-10-27 |
2012-01-04 |
Msd Kk |
Neue benzoxathiinderivate
|
|
JP4371164B2
(ja)
|
2005-11-10 |
2009-11-25 |
萬有製薬株式会社 |
アザ置換スピロ誘導体
|
|
EP1801098A1
(de)
|
2005-12-16 |
2007-06-27 |
Merck Sante |
2-Adamantylharnstoff Derivative als selektive 11B-HSD1 Inhibitoren
|
|
GB0526291D0
(en)
|
2005-12-23 |
2006-02-01 |
Prosidion Ltd |
Therapeutic method
|
|
JP5302012B2
(ja)
*
|
2006-03-08 |
2013-10-02 |
タケダ カリフォルニア インコーポレイテッド |
グルコキナーゼ活性剤
|
|
PE20071221A1
(es)
|
2006-04-11 |
2007-12-14 |
Arena Pharm Inc |
Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
|
|
EP2007734A1
(de)
|
2006-04-12 |
2008-12-31 |
Probiodrug AG |
Enzymhemmer
|
|
PE20110235A1
(es)
|
2006-05-04 |
2011-04-14 |
Boehringer Ingelheim Int |
Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
|
|
EP1852108A1
(de)
|
2006-05-04 |
2007-11-07 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
Zusammensetzungen von DPP-IV-Inhibitoren
|
|
CA2873524C
(en)
|
2006-05-04 |
2018-02-20 |
Boehringer Ingelheim International Gmbh |
A polymeric form of 1-((4-methyl-quinazolin-2-yl)methyl)-3-7-(2-butyn-1-yl)-8-(3-(r)-aminopiperidin-1-yl)xanthine
|
|
WO2008039327A2
(en)
|
2006-09-22 |
2008-04-03 |
Merck & Co., Inc. |
Method of treatment using fatty acid synthesis inhibitors
|
|
EP2072519A4
(de)
|
2006-09-28 |
2009-10-21 |
Banyu Pharma Co Ltd |
Diarylketiminderivat
|
|
EP2089383B1
(de)
|
2006-11-09 |
2015-09-16 |
Probiodrug AG |
3-hydroxy-1,5-dihydropyrrol-2-one derivate als inhibitoren von glutaminylcyclase zur behandlung von geschwüren, krebs und anderen krankheiten
|
|
TW200838536A
(en)
|
2006-11-29 |
2008-10-01 |
Takeda Pharmaceutical |
Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
|
|
SI2091948T1
(sl)
|
2006-11-30 |
2012-07-31 |
Probiodrug Ag |
Novi inhibitorji glutaminil ciklaze
|
|
EP1935420A1
(de)
|
2006-12-21 |
2008-06-25 |
Merck Sante |
2-Adamantyl-Butyramid Derivate als selektive 11Beta-HSD1 Inhibitoren
|
|
EP2123769B1
(de)
|
2007-02-19 |
2016-05-18 |
Kaneka Corporation |
Verfahren zur herstellung von optisch aktivem 3-aminopiperidin oder salz davon
|
|
CA2682727C
(en)
|
2007-04-02 |
2016-03-22 |
Banyu Pharmaceutical Co., Ltd. |
Indoledione derivative
|
|
EP2142514B1
(de)
|
2007-04-18 |
2014-12-24 |
Probiodrug AG |
Thioharnstoffderivate als glutaminylcyclaseinhibitoren
|
|
JP2010526807A
(ja)
|
2007-05-07 |
2010-08-05 |
メルク・シャープ・エンド・ドーム・コーポレイション |
抗糖尿病活性を有する縮合芳香族化合物を用いた治療法
|
|
AU2008261102B2
(en)
|
2007-06-04 |
2013-11-28 |
Bausch Health Ireland Limited |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
|
PE20090938A1
(es)
|
2007-08-16 |
2009-08-08 |
Boehringer Ingelheim Int |
Composicion farmaceutica que comprende un derivado de benceno sustituido con glucopiranosilo
|
|
WO2009110510A1
(ja)
|
2008-03-06 |
2009-09-11 |
萬有製薬株式会社 |
アルキルアミノピリジン誘導体
|
|
WO2009113423A1
(ja)
*
|
2008-03-10 |
2009-09-17 |
大日本住友製薬株式会社 |
二環性ピロール化合物
|
|
US20110015198A1
(en)
|
2008-03-28 |
2011-01-20 |
Banyu Pharmaceutical Co., Inc. |
Diarylmethylamide derivative having melanin-concentrating hormone receptor antagonism
|
|
PE20140960A1
(es)
|
2008-04-03 |
2014-08-15 |
Boehringer Ingelheim Int |
Formulaciones que comprenden un inhibidor de dpp4
|
|
EP2146210A1
(de)
|
2008-04-07 |
2010-01-20 |
Arena Pharmaceuticals, Inc. |
Verfahren zur Verwendung eines AG-Protein-gekoppelten Rezeptors zur Identifikation von Peptid-YY (PPY)-Sekretagogen sowie Verbindungen zur Behandlung durch PYY modulierter Leiden
|
|
EP2110374A1
(de)
|
2008-04-18 |
2009-10-21 |
Merck Sante |
Benzofuran, Benzothiophen, Benzothiazolderivate als FXR-Modulatoren
|
|
EP3239170B1
(de)
|
2008-06-04 |
2019-03-20 |
Synergy Pharmaceuticals Inc. |
Für die behandlung von gastrointestinalen erkrankungen, entzündungen, krebs und anderen erkrankungen geeignete agonisten von guanylatcyclase
|
|
EP2301936A1
(de)
|
2008-06-19 |
2011-03-30 |
Banyu Pharmaceutical Co., Ltd. |
Spirodiamin-diarylketoximid-derivat
|
|
WO2010009319A2
(en)
|
2008-07-16 |
2010-01-21 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
|
|
CA2731358A1
(en)
|
2008-07-30 |
2010-02-04 |
Banyu Pharmaceutical Co., Ltd. |
5/5-or 5/6-membered condensed ring cycloalkylamine derivative
|
|
UY32030A
(es)
|
2008-08-06 |
2010-03-26 |
Boehringer Ingelheim Int |
"tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
|
|
BRPI0916997A2
(pt)
|
2008-08-06 |
2020-12-15 |
Boehringer Ingelheim International Gmbh |
Inibidor de dpp-4 e seu uso
|
|
CN102149407A
(zh)
|
2008-09-10 |
2011-08-10 |
贝林格尔.英格海姆国际有限公司 |
治疗糖尿病和相关病症的组合疗法
|
|
US20200155558A1
(en)
|
2018-11-20 |
2020-05-21 |
Boehringer Ingelheim International Gmbh |
Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
|
|
AU2009307884B2
(en)
|
2008-10-22 |
2014-07-31 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
CN102272103B
(zh)
|
2008-10-30 |
2015-10-21 |
默沙东公司 |
异烟酰胺食欲素受体拮抗剂
|
|
WO2010051206A1
(en)
|
2008-10-31 |
2010-05-06 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
JP5514831B2
(ja)
|
2008-11-17 |
2014-06-04 |
メルク・シャープ・アンド・ドーム・コーポレーション |
糖尿病の治療のための置換二環式アミン
|
|
MX2011006713A
(es)
|
2008-12-23 |
2011-07-13 |
Boehringer Ingelheim Int |
Formas salinas de compuesto organico.
|
|
TW201036975A
(en)
|
2009-01-07 |
2010-10-16 |
Boehringer Ingelheim Int |
Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy
|
|
KR101694136B1
(ko)
|
2009-02-13 |
2017-01-09 |
베링거 인겔하임 인터내셔날 게엠베하 |
Sglt2 억제제, dpp-iv 억제제 및 임의로 추가의 당뇨병 치료제를 포함하는 약제학적 조성물 및 이의 용도
|
|
AR077642A1
(es)
|
2009-07-09 |
2011-09-14 |
Arena Pharm Inc |
Moduladores del metabolismo y el tratamiento de trastornos relacionados con el mismo
|
|
WO2011011506A1
(en)
|
2009-07-23 |
2011-01-27 |
Schering Corporation |
Spirocyclic oxazepine compounds as stearoyl-coenzyme a delta-9 desaturase inhibitors
|
|
WO2011011508A1
(en)
|
2009-07-23 |
2011-01-27 |
Schering Corporation |
Benzo-fused oxazepine compounds as stearoyl-coenzyme a delta-9 desaturase inhibitors
|
|
SG178953A1
(en)
|
2009-09-11 |
2012-04-27 |
Probiodrug Ag |
Heterocylcic derivatives as inhibitors of glutaminyl cyclase
|
|
JP2013510834A
(ja)
|
2009-11-16 |
2013-03-28 |
メリテク |
[1,5]‐ジアゾシン誘導体
|
|
MX364651B
(es)
|
2009-11-27 |
2019-05-03 |
Boehringer Ingelheim Int Gmbh Star |
Inhibidores de dpp-iv, tales como la linagliptina, y composiciones farmacéuticas o combinaciones que comprenden los mismos, para usarse en el tratamiento de pacientes diabéticos tipificados genéticamente.
|
|
CA2784799C
(en)
|
2009-12-30 |
2014-06-10 |
Shanghai Fochon Pharmaceutical Co Ltd |
Certain dipeptidyl peptidase inhibtors
|
|
US8895596B2
(en)
|
2010-02-25 |
2014-11-25 |
Merck Sharp & Dohme Corp |
Cyclic benzimidazole derivatives useful as anti-diabetic agents
|
|
EP2542549B1
(de)
|
2010-03-03 |
2016-05-11 |
Probiodrug AG |
Glutaminylcyclase-hemmer
|
|
WO2011110613A1
(en)
|
2010-03-10 |
2011-09-15 |
Probiodrug Ag |
Heterocyclic inhibitors of glutaminyl cyclase (qc, ec 2.3.2.5)
|
|
CN102286011B
(zh)
*
|
2010-03-16 |
2017-10-03 |
美德(江西)生物科技有限公司 |
吡咯烷硼酸酯二肽基肽酶抑制剂及其药物组合物
|
|
US20130023494A1
(en)
|
2010-04-06 |
2013-01-24 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
US8541596B2
(en)
|
2010-04-21 |
2013-09-24 |
Probiodrug Ag |
Inhibitors
|
|
BR112012028136A2
(pt)
|
2010-05-05 |
2016-08-09 |
Boehringer Ingelheim Int |
terapia de combinaçao
|
|
MX2012014247A
(es)
|
2010-06-24 |
2013-01-18 |
Boehringer Ingelheim Int |
Terapia para la diabetes.
|
|
KR101241085B1
(ko)
|
2010-06-30 |
2013-03-11 |
한국과학기술원 |
잔틴 유도체, 이를 포함하는 pi3k 저해제 조성물 및 pi3k와 연관된 질환 치료에 사용되는 조성물
|
|
US20130156720A1
(en)
|
2010-08-27 |
2013-06-20 |
Ironwood Pharmaceuticals, Inc. |
Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
|
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
|
PH12013500547A1
(en)
|
2010-09-22 |
2013-06-10 |
Arena Pharm Inc |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
US9034883B2
(en)
|
2010-11-15 |
2015-05-19 |
Boehringer Ingelheim International Gmbh |
Vasoprotective and cardioprotective antidiabetic therapy
|
|
EP2648517B1
(de)
*
|
2010-12-06 |
2015-08-05 |
Merck Sharp & Dohme Corp. |
Trizyklische heterozyklen als dipeptidylpeptidase-iv-hemmer
|
|
BR112013021236B1
(pt)
|
2011-02-25 |
2021-05-25 |
Merck Sharp & Dohme Corp |
composto derivado de benzimidazol, e, composição
|
|
CA3100941C
(en)
|
2011-03-01 |
2024-03-05 |
Synergy Pharmaceuticals Inc. |
Process of preparing guanylate cyclase c agonists
|
|
UY33937A
(es)
|
2011-03-07 |
2012-09-28 |
Boehringer Ingelheim Int |
Composiciones farmacéuticas que contienen inhibidores de dpp-4 y/o sglt-2 y metformina
|
|
US8530670B2
(en)
|
2011-03-16 |
2013-09-10 |
Probiodrug Ag |
Inhibitors
|
|
WO2012135570A1
(en)
|
2011-04-01 |
2012-10-04 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
US20140066369A1
(en)
|
2011-04-19 |
2014-03-06 |
Arena Pharmaceuticals, Inc. |
Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
|
|
US20140051714A1
(en)
|
2011-04-22 |
2014-02-20 |
Arena Pharmaceuticals, Inc. |
Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
|
|
US20140038889A1
(en)
|
2011-04-22 |
2014-02-06 |
Arena Pharmaceuticals, Inc. |
Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
|
|
WO2012170702A1
(en)
|
2011-06-08 |
2012-12-13 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
EP2729468A4
(de)
*
|
2011-07-05 |
2015-03-18 |
Merck Sharp & Dohme |
Tricyclische heterozyklen als dipeptidylpeptidase-iv-hemmer
|
|
US8962636B2
(en)
|
2011-07-15 |
2015-02-24 |
Boehringer Ingelheim International Gmbh |
Substituted quinazolines, the preparation thereof and the use thereof in pharmaceutical compositions
|
|
WO2013055910A1
(en)
|
2011-10-12 |
2013-04-18 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
AR088352A1
(es)
|
2011-10-19 |
2014-05-28 |
Merck Sharp & Dohme |
Antagonistas del receptor de 2-piridiloxi-4-nitrilo orexina
|
|
US9555001B2
(en)
|
2012-03-07 |
2017-01-31 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition and uses thereof
|
|
JP6218811B2
(ja)
|
2012-05-14 |
2017-10-25 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Sirs及び/又は敗血症の治療に用いるdpp−4阻害薬としてのキサンチン誘導体
|
|
US20130303462A1
(en)
|
2012-05-14 |
2013-11-14 |
Boehringer Ingelheim International Gmbh |
Use of a dpp-4 inhibitor in podocytes related disorders and/or nephrotic syndrome
|
|
WO2013174767A1
(en)
|
2012-05-24 |
2013-11-28 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
|
|
AU2013296470B2
(en)
|
2012-08-02 |
2016-03-17 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
|
WO2014074668A1
(en)
|
2012-11-08 |
2014-05-15 |
Arena Pharmaceuticals, Inc. |
Modulators of gpr119 and the treatment of disorders related thereto
|
|
US9840512B2
(en)
|
2013-02-22 |
2017-12-12 |
Merck Sharp & Dohme Corp. |
Antidiabetic bicyclic compounds
|
|
US9650375B2
(en)
|
2013-03-14 |
2017-05-16 |
Merck Sharp & Dohme Corp. |
Indole derivatives useful as anti-diabetic agents
|
|
WO2014151200A2
(en)
|
2013-03-15 |
2014-09-25 |
Synergy Pharmaceuticals Inc. |
Compositions useful for the treatment of gastrointestinal disorders
|
|
EP2970384A1
(de)
|
2013-03-15 |
2016-01-20 |
Synergy Pharmaceuticals Inc. |
Agonisten der guanylatcyclase und deren verwendungen
|
|
HRP20240805T1
(hr)
|
2013-06-05 |
2024-09-27 |
Bausch Health Ireland Limited |
Ultra-pročišćeni agonisti guanilat-ciklaze c, postupak njihove pripreme i uporabe
|
|
WO2015051496A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
|
US9526728B2
(en)
|
2014-02-28 |
2016-12-27 |
Boehringer Ingelheim International Gmbh |
Medical use of a DPP-4 inhibitor
|
|
RU2746405C2
(ru)
|
2014-08-29 |
2021-04-13 |
Тес Фарма С.Р.Л. |
ИНГИБИТОРЫ α-АМИНО-β-КАРБОКСИМУКОНАТ-ε-СЕМИАЛЬДЕГИД-ДЕКАРБОКСИЛАЗЫ
|
|
KR20220070057A
(ko)
|
2015-03-09 |
2022-05-27 |
인테크린 테라퓨틱스, 아이엔씨. |
비알코올성 지방간 질환 및/또는 지방이영양증의 치료 방법
|
|
CA3022202A1
(en)
|
2016-06-10 |
2017-12-14 |
Boehringer Ingelheim International Gmbh |
Combinations of linagliptin and metformin
|
|
JP2020500838A
(ja)
|
2016-10-14 |
2020-01-16 |
ティエエッセ ファルマ ソチエタ レスポンサビリタ リミタータ |
Α−アミノ−β−カルボキシムコン酸セミアルデヒドデカルボキシラーゼの阻害剤
|
|
WO2018106518A1
(en)
|
2016-12-06 |
2018-06-14 |
Merck Sharp & Dohme Corp. |
Antidiabetic heterocyclic compounds
|
|
EP3558298A4
(de)
|
2016-12-20 |
2020-08-05 |
Merck Sharp & Dohme Corp. |
Antidiabetische spirochromanverbindungen
|
|
WO2018162722A1
(en)
|
2017-03-09 |
2018-09-13 |
Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke |
Dpp-4 inhibitors for use in treating bone fractures
|
|
CA3058806A1
(en)
|
2017-04-03 |
2018-10-11 |
Coherus Biosciences Inc. |
Ppar.gamma. agonist for treatment of progressive supranuclear palsy
|
|
PL3461819T3
(pl)
|
2017-09-29 |
2020-11-30 |
Probiodrug Ag |
Inhibitory cyklazy glutaminylowej
|
|
IL283182B2
(en)
|
2018-11-20 |
2025-10-01 |
Tes Pharma S R L |
Alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase inhibitors
|
|
WO2020167701A1
(en)
|
2019-02-13 |
2020-08-20 |
Merck Sharp & Dohme Corp. |
Pyrrolidine orexin receptor agonists
|
|
EP3924058B1
(de)
|
2019-02-13 |
2026-01-07 |
Merck Sharp & Dohme LLC |
5-alkyl-pyrrolidinorexinrezeptor-agonisten
|
|
WO2021026047A1
(en)
|
2019-08-08 |
2021-02-11 |
Merck Sharp & Dohme Corp. |
Heteroaryl pyrrolidine and piperidine orexin receptor agonists
|
|
JP7443625B2
(ja)
|
2020-08-18 |
2024-03-05 |
メルク・シャープ・アンド・ドーム・エルエルシー |
ビシクロヘプタンピロリジンオレキシン受容体アゴニスト
|