|
MXPA03007349A
(es)
*
|
2001-02-24 |
2003-12-04 |
Boehringer Ingelheim Pharma |
Derivados de xantina, su preparacion y su empleo como medicamentos.
|
|
ES2296979T3
(es)
|
2001-06-27 |
2008-05-01 |
Smithkline Beecham Corporation |
Fluoropirrolidinas como inhibidores de dipeptidil peptidasa.
|
|
DE60304911D1
(de)
|
2002-02-25 |
2006-06-08 |
Eisai Co Ltd |
Xanthin-Derivate als DPP-IV-Inhibitoren
|
|
CA2485641C
(en)
|
2002-06-06 |
2010-12-14 |
Eisai Co., Ltd. |
Novel condensed imidazole derivatives
|
|
WO2004009091A1
(en)
|
2002-06-17 |
2004-01-29 |
Glaxo Group Limited |
Purine derivatives as liver x receptor agonists
|
|
US7105526B2
(en)
|
2002-06-28 |
2006-09-12 |
Banyu Pharmaceuticals Co., Ltd. |
Benzimidazole derivatives
|
|
US7407955B2
(en)
|
2002-08-21 |
2008-08-05 |
Boehringer Ingelheim Pharma Gmbh & Co., Kg |
8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
|
|
DK1532149T3
(da)
*
|
2002-08-21 |
2010-05-10 |
Boehringer Ingelheim Pharma |
8-[3-amino-piperiden-1-yl]-xanthiner, fremstilling deraf og anvendelse deraf som lægemiddel
|
|
US7495005B2
(en)
|
2002-08-22 |
2009-02-24 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Xanthine derivatives, their preparation and their use in pharmaceutical compositions
|
|
DE10238470A1
(de)
*
|
2002-08-22 |
2004-03-04 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
US7569574B2
(en)
|
2002-08-22 |
2009-08-04 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Purine derivatives, the preparation thereof and their use as pharmaceutical compositions
|
|
AU2003266559B2
(en)
*
|
2002-09-26 |
2008-01-24 |
Eisai R&D Management Co., Ltd. |
Combination drug
|
|
WO2004048379A1
(ja)
*
|
2002-11-01 |
2004-06-10 |
Sumitomo Pharmaceuticals Co., Ltd. |
キサンチン化合物
|
|
US7482337B2
(en)
|
2002-11-08 |
2009-01-27 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
|
|
DE10254304A1
(de)
|
2002-11-21 |
2004-06-03 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
|
KR20050122220A
(ko)
|
2003-03-25 |
2005-12-28 |
다케다 샌디에고, 인코포레이티드 |
디펩티딜 펩티다제 억제제
|
|
JPWO2004096806A1
(ja)
*
|
2003-04-30 |
2006-07-13 |
大日本住友製薬株式会社 |
縮合イミダゾール誘導体
|
|
WO2004098591A2
(en)
|
2003-05-05 |
2004-11-18 |
Probiodrug Ag |
Inhibitors of glutaminyl cyclase and their use in the treatment of neurological diseases
|
|
US7381537B2
(en)
|
2003-05-05 |
2008-06-03 |
Probiodrug Ag |
Use of inhibitors of glutaminyl cyclases for treatment and prevention of disease
|
|
ATE464889T1
(de)
|
2003-05-05 |
2010-05-15 |
Probiodrug Ag |
Medizinische verwendung von hemmern von glutaminyl und glutamatcyclasen
|
|
EP1625122A1
(de)
|
2003-05-14 |
2006-02-15 |
Takeda San Diego, Inc. |
Dipeptidylpeptidase-hemmer
|
|
AU2003902828A0
(en)
*
|
2003-06-05 |
2003-06-26 |
Fujisawa Pharmaceutical Co., Ltd. |
Dpp-iv inhibitor
|
|
US7566707B2
(en)
|
2003-06-18 |
2009-07-28 |
Boehringer Ingelheim International Gmbh |
Imidazopyridazinone and imidazopyridone derivatives, the preparation thereof and their use as pharmaceutical compositions
|
|
KR20060041309A
(ko)
|
2003-08-13 |
2006-05-11 |
다케다 야쿠힌 고교 가부시키가이샤 |
4-피리미돈 유도체 및 펩티딜 펩티다제 저해제로서의 그의용도
|
|
JP4765627B2
(ja)
|
2003-09-22 |
2011-09-07 |
Msd株式会社 |
新規ピペリジン誘導体
|
|
EP2289498A1
(de)
|
2003-10-15 |
2011-03-02 |
Probiodrug AG |
Verwendung von Inhibioten von Glutaminyl Cyclase
|
|
AU2004290499C1
(en)
|
2003-11-03 |
2011-02-24 |
Probiodrug Ag |
Combinations useful for the treatment of neuronal disorders
|
|
KR20140089408A
(ko)
|
2003-11-17 |
2014-07-14 |
노파르티스 아게 |
디펩티딜 펩티다제 ⅳ 억제제의 용도
|
|
WO2005051949A1
(ja)
*
|
2003-11-26 |
2005-06-09 |
Dainippon Sumitomo Pharma Co., Ltd. |
新規縮合イミダゾール誘導体
|
|
DE10355304A1
(de)
*
|
2003-11-27 |
2005-06-23 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue 8-(Piperazin-1-yl)-und 8-([1,4]Diazepan-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
WO2005053695A1
(ja)
*
|
2003-12-04 |
2005-06-16 |
Eisai Co., Ltd. |
多発性硬化症予防剤または治療剤
|
|
SI1715893T1
(sl)
|
2004-01-20 |
2009-12-31 |
Novartis Pharma Ag |
Direktna kompresijska formulacija in postopek
|
|
EP1713780B1
(de)
|
2004-02-05 |
2012-01-18 |
Probiodrug AG |
Neue inhibitoren von glutaminylcyclase
|
|
CA2554493C
(en)
|
2004-02-05 |
2012-06-26 |
Kyorin Pharmaceutical Co., Ltd. |
Bicycloester derivative
|
|
BRPI0507873B8
(pt)
*
|
2004-02-18 |
2021-05-25 |
Boehringer Ingelheim Int |
8-[3-amino-piperidin-1-il]-xantinas, seu processo de produção, seu uso como inibidor de dpp-iv e medicamento
|
|
US7501426B2
(en)
|
2004-02-18 |
2009-03-10 |
Boehringer Ingelheim International Gmbh |
8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
|
|
DE102004009039A1
(de)
|
2004-02-23 |
2005-09-08 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
8-[3-Amino-piperidin-1-yl]-xanthine, deren Herstellung und Verwendung als Arzneimittel
|
|
US7393847B2
(en)
|
2004-03-13 |
2008-07-01 |
Boehringer Ingleheim International Gmbh |
Imidazopyridazinediones, their preparation and their use as pharmaceutical compositions
|
|
AU2005230864A1
(en)
|
2004-03-29 |
2005-10-20 |
Merck Sharp & Dohme Corp. |
Diaryltriazoles as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1
|
|
US20080125403A1
(en)
|
2004-04-02 |
2008-05-29 |
Merck & Co., Inc. |
Method of Treating Men with Metabolic and Anthropometric Disorders
|
|
US7439370B2
(en)
|
2004-05-10 |
2008-10-21 |
Boehringer Ingelheim International Gmbh |
Imidazole derivatives, their preparation and their use as intermediates for the preparation of pharmaceutical compositions and pesticides
|
|
DE102004030502A1
(de)
|
2004-06-24 |
2006-01-12 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Imidazole und Triazole, deren Herstellung und Verwendung als Arzneimittel
|
|
CN1993320A
(zh)
|
2004-08-06 |
2007-07-04 |
默克公司 |
作为11-β-羟基类固醇脱氢酶-1的抑制剂的磺酰化合物
|
|
DE102004043944A1
(de)
|
2004-09-11 |
2006-03-30 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue 8-(3-Amino-piperidin-1-yl)-7-(but-2-inyl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
DE102004044221A1
(de)
|
2004-09-14 |
2006-03-16 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue 3-Methyl-7-butinyl-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
US7884104B2
(en)
|
2004-10-01 |
2011-02-08 |
Merck Sharp & Dohme Corp. |
Aminopiperidines as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
|
|
DE102004054054A1
(de)
|
2004-11-05 |
2006-05-11 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
|
|
MX2007007483A
(es)
*
|
2004-12-24 |
2007-07-20 |
Dainippon Sumitomo Pharma Co |
Derivados de pirroles biciclicos.
|
|
DOP2006000008A
(es)
|
2005-01-10 |
2006-08-31 |
Arena Pharm Inc |
Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1
|
|
RU2417985C2
(ru)
|
2005-05-30 |
2011-05-10 |
Баниу Фармасьютикал Ко., Лтд. |
Новые производные пиперидина
|
|
MY152185A
(en)
|
2005-06-10 |
2014-08-29 |
Novartis Ag |
Modified release 1-[(3-hydroxy-adamant-1-ylamino)-acetyl]-pyrrolidine-2(s)-carbonitrile formulation
|
|
DE102005035891A1
(de)
|
2005-07-30 |
2007-02-08 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
GB0516464D0
(en)
*
|
2005-08-10 |
2005-09-14 |
Smithkline Beecham Corp |
Novel compounds
|
|
WO2007018248A1
(ja)
|
2005-08-10 |
2007-02-15 |
Banyu Pharmaceutical Co., Ltd. |
ピリドン化合物
|
|
GB0516462D0
(en)
*
|
2005-08-10 |
2005-09-14 |
Smithkline Beecham Corp |
Novel compounds
|
|
HRP20100725T1
(hr)
*
|
2005-08-10 |
2011-01-31 |
Glaxosmithkline Llc |
Derivati ksantina kao selektivni agonisti hm74a
|
|
CA2619770A1
(en)
|
2005-08-24 |
2007-03-01 |
Banyu Pharmaceutical Co., Ltd. |
Phenylpyridone derivative
|
|
US20090264426A1
(en)
|
2005-09-07 |
2009-10-22 |
Shunji Sakuraba |
Bicyclic aromatic substituted pyridone derivative
|
|
PT1942898E
(pt)
|
2005-09-14 |
2011-12-20 |
Takeda Pharmaceutical |
Inibidores da dipeptidilpeptidase para o tratamento da diabetes
|
|
CN101360723A
(zh)
|
2005-09-16 |
2009-02-04 |
武田药品工业株式会社 |
制备嘧啶二酮衍生物的方法
|
|
BRPI0616463A2
(pt)
|
2005-09-29 |
2011-06-21 |
Merck & Co Inc |
composto, composição farmacêutica, e, uso de um composto
|
|
EP1944301A4
(de)
|
2005-10-27 |
2012-01-04 |
Msd Kk |
Neue benzoxathiinderivate
|
|
US8158791B2
(en)
|
2005-11-10 |
2012-04-17 |
Msd K.K. |
Aza-substituted spiro derivatives
|
|
EP1801098A1
(de)
|
2005-12-16 |
2007-06-27 |
Merck Sante |
2-Adamantylharnstoff Derivative als selektive 11B-HSD1 Inhibitoren
|
|
GB0526291D0
(en)
|
2005-12-23 |
2006-02-01 |
Prosidion Ltd |
Therapeutic method
|
|
JP5302012B2
(ja)
*
|
2006-03-08 |
2013-10-02 |
タケダ カリフォルニア インコーポレイテッド |
グルコキナーゼ活性剤
|
|
PE20071221A1
(es)
|
2006-04-11 |
2007-12-14 |
Arena Pharm Inc |
Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
|
|
CA2649209A1
(en)
|
2006-04-12 |
2007-10-18 |
Probiodrug Ag |
Enzyme inhibitors
|
|
PE20080251A1
(es)
|
2006-05-04 |
2008-04-25 |
Boehringer Ingelheim Int |
Usos de inhibidores de dpp iv
|
|
MX2008014024A
(es)
|
2006-05-04 |
2008-11-14 |
Boehringer Ingelheim Int |
Formas poliformas.
|
|
EP1852108A1
(de)
|
2006-05-04 |
2007-11-07 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
Zusammensetzungen von DPP-IV-Inhibitoren
|
|
EP2698157B1
(de)
|
2006-09-22 |
2015-05-20 |
Merck Sharp & Dohme Corp. |
Verfahren zur Behandlung von Fettsäure-Synthese-Hemmern
|
|
US20090247560A1
(en)
|
2006-09-28 |
2009-10-01 |
Banyu Pharmaceutical Co., Ltd. |
Diaryl ketimine derivative
|
|
EP2089383B1
(de)
|
2006-11-09 |
2015-09-16 |
Probiodrug AG |
3-hydroxy-1,5-dihydropyrrol-2-one derivate als inhibitoren von glutaminylcyclase zur behandlung von geschwüren, krebs und anderen krankheiten
|
|
TW200838536A
(en)
|
2006-11-29 |
2008-10-01 |
Takeda Pharmaceutical |
Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
|
|
US9126987B2
(en)
|
2006-11-30 |
2015-09-08 |
Probiodrug Ag |
Inhibitors of glutaminyl cyclase
|
|
EP1935420A1
(de)
|
2006-12-21 |
2008-06-25 |
Merck Sante |
2-Adamantyl-Butyramid Derivate als selektive 11Beta-HSD1 Inhibitoren
|
|
EP2123769B1
(de)
|
2007-02-19 |
2016-05-18 |
Kaneka Corporation |
Verfahren zur herstellung von optisch aktivem 3-aminopiperidin oder salz davon
|
|
JP5319518B2
(ja)
|
2007-04-02 |
2013-10-16 |
Msd株式会社 |
インドールジオン誘導体
|
|
WO2008128985A1
(en)
|
2007-04-18 |
2008-10-30 |
Probiodrug Ag |
Thiourea derivatives as glutaminyl cyclase inhibitors
|
|
CA2688187C
(en)
|
2007-05-07 |
2016-10-11 |
Merck & Co., Inc. |
Method of treament using fused aromatic compounds having anti-diabetic activity
|
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
|
US8034782B2
(en)
|
2008-07-16 |
2011-10-11 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
|
WO2008151257A2
(en)
|
2007-06-04 |
2008-12-11 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
|
PE20090938A1
(es)
|
2007-08-16 |
2009-08-08 |
Boehringer Ingelheim Int |
Composicion farmaceutica que comprende un derivado de benceno sustituido con glucopiranosilo
|
|
US20110015181A1
(en)
|
2008-03-06 |
2011-01-20 |
Makoto Ando |
Alkylaminopyridine derivative
|
|
EP2264034A1
(de)
*
|
2008-03-10 |
2010-12-22 |
Dainippon Sumitomo Pharma Co., Ltd. |
Bicyclische pyrrolverbindung
|
|
US20110015198A1
(en)
|
2008-03-28 |
2011-01-20 |
Banyu Pharmaceutical Co., Inc. |
Diarylmethylamide derivative having melanin-concentrating hormone receptor antagonism
|
|
PE20091730A1
(es)
|
2008-04-03 |
2009-12-10 |
Boehringer Ingelheim Int |
Formulaciones que comprenden un inhibidor de dpp4
|
|
EP2108960A1
(de)
|
2008-04-07 |
2009-10-14 |
Arena Pharmaceuticals, Inc. |
Verfahren zur Verwendung eines A G Protein-gekoppelten Rezeptors zur Identifikation von Peptid YY (PYY) Sekretagoga und nützliche Verbindungen zur Behandlung von durch (PYY) Sekretagoga modulierten Zuständen und nützliche Verbindungen zur Behandlung von Zuständen durch PYY
|
|
EP2110374A1
(de)
|
2008-04-18 |
2009-10-21 |
Merck Sante |
Benzofuran, Benzothiophen, Benzothiazolderivate als FXR-Modulatoren
|
|
EP2810951B1
(de)
|
2008-06-04 |
2017-03-15 |
Synergy Pharmaceuticals Inc. |
Für die Behandlung von gastrointestinalen Erkrankungen, Entzündungen, Krebs und anderen Erkrankungen geeignete Agonisten von Guanylatcyclase
|
|
CA2727914A1
(en)
|
2008-06-19 |
2009-12-23 |
Banyu Pharmaceutical Co., Ltd. |
Spirodiamine-diaryl ketoxime derivative technical field
|
|
AU2009277736A1
(en)
|
2008-07-30 |
2010-02-04 |
Banyu Pharmaceutical Co., Ltd. |
(5-membered)-(5-membered) or (5-membered)-(6-membered) fused ring cycloalkylamine derivative
|
|
UY32030A
(es)
|
2008-08-06 |
2010-03-26 |
Boehringer Ingelheim Int |
"tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
|
|
BRPI0916997A2
(pt)
|
2008-08-06 |
2020-12-15 |
Boehringer Ingelheim International Gmbh |
Inibidor de dpp-4 e seu uso
|
|
MX2011002558A
(es)
|
2008-09-10 |
2011-04-26 |
Boehringer Ingelheim Int |
Terapia de combinacion para el tratamiento de diabetes y estados relacionados.
|
|
US20200155558A1
(en)
|
2018-11-20 |
2020-05-21 |
Boehringer Ingelheim International Gmbh |
Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
|
|
US8410284B2
(en)
|
2008-10-22 |
2013-04-02 |
Merck Sharp & Dohme Corp |
Cyclic benzimidazole derivatives useful as anti-diabetic agents
|
|
MX2011004551A
(es)
|
2008-10-30 |
2011-05-25 |
Merck Sharp & Dohme |
Antagonistas del receptor de orexina de isonicotinamida.
|
|
US8329914B2
(en)
|
2008-10-31 |
2012-12-11 |
Merck Sharp & Dohme Corp |
Cyclic benzimidazole derivatives useful as anti-diabetic agents
|
|
JP5514831B2
(ja)
|
2008-11-17 |
2014-06-04 |
メルク・シャープ・アンド・ドーム・コーポレーション |
糖尿病の治療のための置換二環式アミン
|
|
EP2382216A1
(de)
|
2008-12-23 |
2011-11-02 |
Boehringer Ingelheim International GmbH |
Salzformen einer organischen verbindung
|
|
TW201036975A
(en)
|
2009-01-07 |
2010-10-16 |
Boehringer Ingelheim Int |
Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy
|
|
EP2395983B1
(de)
|
2009-02-13 |
2020-04-08 |
Boehringer Ingelheim International GmbH |
Pharmazeutische zusammensetzung mit einem sglt2-inhibitor, einem dpp-iv-inhibitor und optional einem weiteren antidiabetischen mittel und ihre verwendung
|
|
AR077642A1
(es)
|
2009-07-09 |
2011-09-14 |
Arena Pharm Inc |
Moduladores del metabolismo y el tratamiento de trastornos relacionados con el mismo
|
|
WO2011011506A1
(en)
|
2009-07-23 |
2011-01-27 |
Schering Corporation |
Spirocyclic oxazepine compounds as stearoyl-coenzyme a delta-9 desaturase inhibitors
|
|
US20120220567A1
(en)
|
2009-07-23 |
2012-08-30 |
Shipps Jr Gerald W |
Benzo-fused oxazepine compounds as stearoyl-coenzyme a delta-9 desaturase inhibitors
|
|
CA2772488C
(en)
|
2009-09-11 |
2018-04-17 |
Probiodrug Ag |
Heterocyclic derivatives as inhibitors of glutaminyl cyclase
|
|
CN102812011A
(zh)
|
2009-11-16 |
2012-12-05 |
梅利科技公司 |
[1,5]-二氮杂环辛间四烯衍生物
|
|
EP3646859A1
(de)
|
2009-11-27 |
2020-05-06 |
Boehringer Ingelheim International GmbH |
Behandlung von genotypisierten diabetes-patienten mit dpp-iv-hemmern wie etwa linagliptin
|
|
WO2011079778A1
(en)
|
2009-12-30 |
2011-07-07 |
China Shanghai Fochon Pharmaceutical Co Ltd |
3-(3-aminopiperidin-1-yl)-5-oxo-1,2,4-triazine derivates as dipeptidyl peptidase iv(dpp-iv) inhibitors
|
|
JP2013520502A
(ja)
|
2010-02-25 |
2013-06-06 |
メルク・シャープ・エンド・ドーム・コーポレイション |
有用な抗糖尿病薬である新規な環状ベンズイミダゾール誘導体
|
|
JP6026284B2
(ja)
|
2010-03-03 |
2016-11-16 |
プロビオドルグ エージー |
グルタミニルシクラーゼの阻害剤
|
|
NZ602312A
(en)
|
2010-03-10 |
2014-02-28 |
Probiodrug Ag |
Heterocyclic inhibitors of glutaminyl cyclase (qc, ec 2.3.2.5)
|
|
CN102286011B
(zh)
*
|
2010-03-16 |
2017-10-03 |
美德(江西)生物科技有限公司 |
吡咯烷硼酸酯二肽基肽酶抑制剂及其药物组合物
|
|
JP2013523819A
(ja)
|
2010-04-06 |
2013-06-17 |
アリーナ ファーマシューティカルズ, インコーポレイテッド |
Gpr119レセプターのモジュレーターおよびそれに関連する障害の処置
|
|
JP5945532B2
(ja)
|
2010-04-21 |
2016-07-05 |
プロビオドルグ エージー |
グルタミニルシクラーゼの阻害剤としてのベンゾイミダゾール誘導体
|
|
AU2011249722B2
(en)
|
2010-05-05 |
2015-09-17 |
Boehringer Ingelheim International Gmbh |
Combination therapy
|
|
CN106975074A
(zh)
|
2010-06-24 |
2017-07-25 |
勃林格殷格翰国际有限公司 |
糖尿病治疗
|
|
KR101241085B1
(ko)
|
2010-06-30 |
2013-03-11 |
한국과학기술원 |
잔틴 유도체, 이를 포함하는 pi3k 저해제 조성물 및 pi3k와 연관된 질환 치료에 사용되는 조성물
|
|
WO2012027331A1
(en)
|
2010-08-27 |
2012-03-01 |
Ironwood Pharmaceuticals, Inc. |
Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
|
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
|
PH12013500547A1
(en)
|
2010-09-22 |
2013-06-10 |
Arena Pharm Inc |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
AR083878A1
(es)
|
2010-11-15 |
2013-03-27 |
Boehringer Ingelheim Int |
Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
|
|
WO2012078448A1
(en)
*
|
2010-12-06 |
2012-06-14 |
Schering Corporation |
Tricyclic heterocycles useful as dipeptidyl peptidase-iv inhibitors
|
|
PH12013501686A1
(en)
|
2011-02-25 |
2017-10-25 |
Merck Sharp & Dohme |
Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents
|
|
CN107090016A
(zh)
|
2011-03-01 |
2017-08-25 |
辛纳吉制药公司 |
制备鸟苷酸环化酶c激动剂的方法
|
|
AR085689A1
(es)
|
2011-03-07 |
2013-10-23 |
Boehringer Ingelheim Int |
Composiciones farmaceuticas de metformina, linagliptina y un inhibidor de sglt-2
|
|
EP2686313B1
(de)
|
2011-03-16 |
2016-02-03 |
Probiodrug AG |
Benzimidazolderivate als glutaminylcyclase-hemmer
|
|
US20140018371A1
(en)
|
2011-04-01 |
2014-01-16 |
Arena Pharmaceuticals, Inc. |
Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
|
|
WO2012145361A1
(en)
|
2011-04-19 |
2012-10-26 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
WO2012145603A1
(en)
|
2011-04-22 |
2012-10-26 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
WO2012145604A1
(en)
|
2011-04-22 |
2012-10-26 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
WO2012170702A1
(en)
|
2011-06-08 |
2012-12-13 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
EP2729468A4
(de)
*
|
2011-07-05 |
2015-03-18 |
Merck Sharp & Dohme |
Tricyclische heterozyklen als dipeptidylpeptidase-iv-hemmer
|
|
PH12014500137A1
(en)
|
2011-07-15 |
2017-08-18 |
Boehringer Ingelheim Int |
Substituted quinazolines, the preparation thereof and the use thereof in pharmaceutical compositions
|
|
WO2013055910A1
(en)
|
2011-10-12 |
2013-04-18 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
AR088352A1
(es)
|
2011-10-19 |
2014-05-28 |
Merck Sharp & Dohme |
Antagonistas del receptor de 2-piridiloxi-4-nitrilo orexina
|
|
US9555001B2
(en)
|
2012-03-07 |
2017-01-31 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition and uses thereof
|
|
WO2013171167A1
(en)
|
2012-05-14 |
2013-11-21 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome
|
|
US20130303554A1
(en)
|
2012-05-14 |
2013-11-14 |
Boehringer Ingelheim International Gmbh |
Use of a dpp-4 inhibitor in sirs and/or sepsis
|
|
WO2013174767A1
(en)
|
2012-05-24 |
2013-11-28 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
|
|
CA2880901A1
(en)
|
2012-08-02 |
2014-02-06 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
|
WO2014074668A1
(en)
|
2012-11-08 |
2014-05-15 |
Arena Pharmaceuticals, Inc. |
Modulators of gpr119 and the treatment of disorders related thereto
|
|
RU2015140066A
(ru)
|
2013-02-22 |
2017-03-30 |
Мерк Шарп И Доум Корп. |
Противодиабетические бициклические соединения
|
|
WO2014139388A1
(en)
|
2013-03-14 |
2014-09-18 |
Merck Sharp & Dohme Corp. |
Novel indole derivatives useful as anti-diabetic agents
|
|
US9708367B2
(en)
|
2013-03-15 |
2017-07-18 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase and their uses
|
|
AU2014235209B2
(en)
|
2013-03-15 |
2018-06-14 |
Bausch Health Ireland Limited |
Guanylate cyclase receptor agonists combined with other drugs
|
|
CN105764916B
(zh)
|
2013-06-05 |
2021-05-18 |
博士医疗爱尔兰有限公司 |
鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
|
|
WO2015051496A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
|
EP3110449B1
(de)
|
2014-02-28 |
2023-06-28 |
Boehringer Ingelheim International GmbH |
Medizinische verwendung eines dpp-4-inhibitors
|
|
RU2021109549A
(ru)
|
2014-08-29 |
2021-05-13 |
Тес Фарма С.Р.Л. |
ИНГИБИТОРЫ α-АМИНО-β-КАРБОКСИМУКОНАТ ε-СЕМИАЛЬДЕГИД-ДЕКАРБОКСИЛАЗЫ
|
|
MX386778B
(es)
|
2015-03-09 |
2025-03-19 |
Intekrin Therapeutics Inc |
Métodos para el tratamiento de enfermedad de hígado graso no alcohólico y/o lipodistrofia.
|
|
WO2017211979A1
(en)
|
2016-06-10 |
2017-12-14 |
Boehringer Ingelheim International Gmbh |
Combinations of linagliptin and metformin
|
|
AU2017342083A1
(en)
|
2016-10-14 |
2019-04-11 |
Tes Pharma S.R.L. |
Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
|
|
US11072602B2
(en)
|
2016-12-06 |
2021-07-27 |
Merck Sharp & Dohme Corp. |
Antidiabetic heterocyclic compounds
|
|
WO2018118670A1
(en)
|
2016-12-20 |
2018-06-28 |
Merck Sharp & Dohme Corp. |
Antidiabetic spirochroman compounds
|
|
WO2018162722A1
(en)
|
2017-03-09 |
2018-09-13 |
Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke |
Dpp-4 inhibitors for use in treating bone fractures
|
|
CA3058806A1
(en)
|
2017-04-03 |
2018-10-11 |
Coherus Biosciences Inc. |
Ppar.gamma. agonist for treatment of progressive supranuclear palsy
|
|
ES2812698T3
(es)
|
2017-09-29 |
2021-03-18 |
Probiodrug Ag |
Inhibidores de glutaminil ciclasa
|
|
MX2021005904A
(es)
|
2018-11-20 |
2021-09-08 |
Tes Pharma S R L |
Inhibidores de la ácido alfa-amino-beta-carboximucónico semialdehído descarboxilasa.
|
|
US12331018B2
(en)
|
2019-02-13 |
2025-06-17 |
Merck Sharp & Dohme Llc |
Pyrrolidine orexin receptor agonists
|
|
EP3924058A1
(de)
|
2019-02-13 |
2021-12-22 |
Merck Sharp & Dohme Corp. |
5-alkyl-pyrrolidinorexinrezeptor-agonisten
|
|
WO2021026047A1
(en)
|
2019-08-08 |
2021-02-11 |
Merck Sharp & Dohme Corp. |
Heteroaryl pyrrolidine and piperidine orexin receptor agonists
|
|
GEAP202416395A
(en)
|
2020-08-18 |
2024-02-12 |
Merck Sharp & Dohme Llc |
Bicycloheptane pyrrolidine orexin receptor agonists
|