DE60304911D1 - Xanthin-Derivate als DPP-IV-Inhibitoren - Google Patents

Xanthin-Derivate als DPP-IV-Inhibitoren

Info

Publication number
DE60304911D1
DE60304911D1 DE60304911T DE60304911T DE60304911D1 DE 60304911 D1 DE60304911 D1 DE 60304911D1 DE 60304911 T DE60304911 T DE 60304911T DE 60304911 T DE60304911 T DE 60304911T DE 60304911 D1 DE60304911 D1 DE 60304911D1
Authority
DE
Germany
Prior art keywords
dpp
inhibitors
xanthine derivatives
xanthine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60304911T
Other languages
English (en)
Inventor
Seiji Yoshikawa
Eita Emori
Fumiyoshi Matsuura
Richard Clark
Hironori Ikuta
Nobuyuki Yasuda
Tadashi Nagakura
Kazuto Yamazaki
Mika Aoki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of DE60304911D1 publication Critical patent/DE60304911D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60304911T 2002-02-25 2003-02-24 Xanthin-Derivate als DPP-IV-Inhibitoren Expired - Lifetime DE60304911D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002047761 2002-02-25
JP2002149557 2002-05-23

Publications (1)

Publication Number Publication Date
DE60304911D1 true DE60304911D1 (de) 2006-06-08

Family

ID=27667558

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60304911T Expired - Lifetime DE60304911D1 (de) 2002-02-25 2003-02-24 Xanthin-Derivate als DPP-IV-Inhibitoren

Country Status (3)

Country Link
US (1) US7074798B2 (de)
EP (1) EP1338595B1 (de)
DE (1) DE60304911D1 (de)

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RU2297418C9 (ru) * 2002-06-06 2009-01-27 Эйсай Ко., Лтд. Новые конденсированные производные имидазола, ингибитор дипептидилпептидазы iv, фармацевтическая композиция, способ лечения и применение на их основе
KR100867485B1 (ko) 2002-09-26 2008-11-10 에자이 알앤드디 매니지먼트 가부시키가이샤 병용 의약
CN100376573C (zh) 2002-12-04 2008-03-26 卫材R&D管理有限公司 稠合的1,3-二氢-咪唑环化合物
US6966269B2 (en) 2002-12-18 2005-11-22 Brian Sawatzky Multi-purpose garden tool

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US20040082570A1 (en) 2004-04-29
EP1338595B1 (de) 2006-05-03
EP1338595A3 (de) 2003-10-08
US7074798B2 (en) 2006-07-11

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