MXPA02012272A - Compuestos heterociclicos que son inhibidores de la enzima dipeptidilpeptidasa-iv. - Google Patents

Compuestos heterociclicos que son inhibidores de la enzima dipeptidilpeptidasa-iv.

Info

Publication number
MXPA02012272A
MXPA02012272A MXPA02012272A MXPA02012272A MXPA02012272A MX PA02012272 A MXPA02012272 A MX PA02012272A MX PA02012272 A MXPA02012272 A MX PA02012272A MX PA02012272 A MXPA02012272 A MX PA02012272A MX PA02012272 A MXPA02012272 A MX PA02012272A
Authority
MX
Mexico
Prior art keywords
dpp
inhibitors
heterocyclic compounds
enzyme dpp
compounds
Prior art date
Application number
MXPA02012272A
Other languages
English (en)
Inventor
Anders Bendtz Kanstrup
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of MXPA02012272A publication Critical patent/MXPA02012272A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La presente invencion se relaciona con inhibidores terapeuticamente activos y selectivos de la enzima DPP-IV, composiciones farmaceuticos que comprenden los compuestos y el uso de tales compuestos asi como la elaboracion de medicamentos para tratar enfermedades que esten relacionadas con proteinas que se someten a inactivacion por DPP-IV, tales como diabetes tipo II y obesidad, asi como metodos para tratar enfermedades que esten relacionadas con proteinas que se someten a inactivacion por DPP-IV, tales como diabetes tipo II y obesidad.
MXPA02012272A 2000-07-04 2001-07-04 Compuestos heterociclicos que son inhibidores de la enzima dipeptidilpeptidasa-iv. MXPA02012272A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200001040 2000-07-04
US22324000P 2000-08-04 2000-08-04
PCT/DK2001/000467 WO2002002560A2 (en) 2000-07-04 2001-07-04 Purine-2,6-diones which are inhibitors of the enzyme dipeptidyl peptidase iv (dpp-iv)

Publications (1)

Publication Number Publication Date
MXPA02012272A true MXPA02012272A (es) 2003-04-25

Family

ID=26068848

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02012272A MXPA02012272A (es) 2000-07-04 2001-07-04 Compuestos heterociclicos que son inhibidores de la enzima dipeptidilpeptidasa-iv.

Country Status (8)

Country Link
US (2) US20020161001A1 (es)
EP (1) EP1301187B1 (es)
JP (1) JP2004502690A (es)
AU (2) AU2001268958B2 (es)
HU (1) HUP0301622A3 (es)
MX (1) MXPA02012272A (es)
PL (1) PL360856A1 (es)
WO (1) WO2002002560A2 (es)

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* Cited by examiner, † Cited by third party
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