IL116584A0 - Novel flavin adenine dinucleotide analogue inhibitors of monoamine oxidase - Google Patents

Novel flavin adenine dinucleotide analogue inhibitors of monoamine oxidase

Info

Publication number
IL116584A0
IL116584A0 IL11658495A IL11658495A IL116584A0 IL 116584 A0 IL116584 A0 IL 116584A0 IL 11658495 A IL11658495 A IL 11658495A IL 11658495 A IL11658495 A IL 11658495A IL 116584 A0 IL116584 A0 IL 116584A0
Authority
IL
Israel
Prior art keywords
adenine dinucleotide
monoamine oxidase
flavin adenine
dinucleotide analogue
analogue inhibitors
Prior art date
Application number
IL11658495A
Original Assignee
Res Dev Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/449,311 external-priority patent/US5756479A/en
Application filed by Res Dev Foundation filed Critical Res Dev Foundation
Publication of IL116584A0 publication Critical patent/IL116584A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • C07H19/20Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C07H19/207Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids the phosphoric or polyphosphoric acids being esterified by a further hydroxylic compound, e.g. flavine adenine dinucleotide or nicotinamide-adenine dinucleotide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
IL11658495A 1994-12-29 1995-12-27 Novel flavin adenine dinucleotide analogue inhibitors of monoamine oxidase IL116584A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36578294A 1994-12-29 1994-12-29
US08/449,311 US5756479A (en) 1994-12-29 1995-05-24 Flavin adenine dinucleotide analogue inhibitors of monoamine oxidase

Publications (1)

Publication Number Publication Date
IL116584A0 true IL116584A0 (en) 1996-03-31

Family

ID=27003091

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11658495A IL116584A0 (en) 1994-12-29 1995-12-27 Novel flavin adenine dinucleotide analogue inhibitors of monoamine oxidase

Country Status (3)

Country Link
AU (1) AU4745496A (en)
IL (1) IL116584A0 (en)
WO (1) WO1996020946A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9610376D0 (en) * 1996-05-17 1996-07-24 Univ Leicester Enzyme-electron acceptor assembly
GB2330143B (en) * 1996-05-17 2000-04-05 Univ Leicester Enzyme-electron acceptor assembly
US7732162B2 (en) 2003-05-05 2010-06-08 Probiodrug Ag Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases
US8278345B2 (en) 2006-11-09 2012-10-02 Probiodrug Ag Inhibitors of glutaminyl cyclase
JP5523107B2 (en) 2006-11-30 2014-06-18 プロビオドルグ エージー Novel inhibitors of glutaminyl cyclase
NZ579310A (en) 2007-03-01 2012-03-30 Probiodrug Ag Use of glutaminyl cyclase inhibitors for the treatment of mild cognitive impairment and diagnostic purposes thereof
EP2142514B1 (en) 2007-04-18 2014-12-24 Probiodrug AG Thiourea derivatives as glutaminyl cyclase inhibitors
CA2772488C (en) 2009-09-11 2018-04-17 Probiodrug Ag Heterocyclic derivatives as inhibitors of glutaminyl cyclase
US9181233B2 (en) 2010-03-03 2015-11-10 Probiodrug Ag Inhibitors of glutaminyl cyclase
US8269019B2 (en) 2010-03-10 2012-09-18 Probiodrug Ag Inhibitors
EP2560953B1 (en) 2010-04-21 2016-01-06 Probiodrug AG Inhibitors of glutaminyl cyclase
JP6050264B2 (en) 2011-03-16 2016-12-21 プロビオドルグ エージー Benzimidazole derivatives as inhibitors of glutaminyl cyclase
PL3461819T3 (en) 2017-09-29 2020-11-30 Probiodrug Ag Inhibitors of glutaminyl cyclase

Also Published As

Publication number Publication date
AU4745496A (en) 1996-07-24
WO1996020946A1 (en) 1996-07-11

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