|
US6100387A
(en)
*
|
1997-02-28 |
2000-08-08 |
Genetics Institute, Inc. |
Chimeric polypeptides containing chemokine domains
|
|
US6852508B1
(en)
|
1997-02-28 |
2005-02-08 |
Genetics Institute, Llc |
Chemokine with amino-terminal modifications
|
|
ES2221717T3
(es)
|
1997-12-08 |
2005-01-01 |
Emd Lexigen Research Center Corp. |
Proteinas de fusion heterodimeras utiles para inmunoterapia dirigida e inmunoestimulacion general.
|
|
US6528624B1
(en)
|
1998-04-02 |
2003-03-04 |
Genentech, Inc. |
Polypeptide variants
|
|
US20020142374A1
(en)
*
|
1998-08-17 |
2002-10-03 |
Michael Gallo |
Generation of modified molecules with increased serum half-lives
|
|
US6660843B1
(en)
*
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
|
US7488590B2
(en)
|
1998-10-23 |
2009-02-10 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
|
DK2319928T3
(da)
|
1998-10-23 |
2013-06-24 |
Kirin Amgen Inc |
Dimere trombopoietiske peptidomimetika, der binder til MPL-receptor og har trombopoietisk aktivitet
|
|
GB9824632D0
(en)
|
1998-11-10 |
1999-01-06 |
Celltech Therapeutics Ltd |
Biological compounds
|
|
US7183387B1
(en)
|
1999-01-15 |
2007-02-27 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
KR101077001B1
(ko)
|
1999-01-15 |
2011-10-26 |
제넨테크, 인크. |
효과기 기능이 변화된 폴리펩티드 변이체
|
|
GB9908263D0
(en)
*
|
1999-04-13 |
1999-06-02 |
Binding Site The Limited |
Eliciting improved immune responses
|
|
US7291714B1
(en)
|
1999-06-30 |
2007-11-06 |
Millennium Pharmaceuticals, Inc. |
Glycoprotein VI and uses thereof
|
|
US7067110B1
(en)
|
1999-07-21 |
2006-06-27 |
Emd Lexigen Research Center Corp. |
Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
|
US6617135B1
(en)
|
1999-08-09 |
2003-09-09 |
Emd Lexigen Research Center Corp. |
Multiple cytokine protein complexes
|
|
US7459540B1
(en)
|
1999-09-07 |
2008-12-02 |
Amgen Inc. |
Fibroblast growth factor-like polypeptides
|
|
CA2391080A1
(en)
|
1999-11-12 |
2001-05-25 |
Merck Patent Gesellschaft Mit Beschraenkter Haftung |
Erythropoietin forms with improved properties
|
|
US6808902B1
(en)
|
1999-11-12 |
2004-10-26 |
Amgen Inc. |
Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
|
|
US7229619B1
(en)
|
2000-11-28 |
2007-06-12 |
Medimmune, Inc. |
Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
|
|
DK1252192T3
(da)
|
2000-02-11 |
2006-11-20 |
Merck Patent Gmbh |
Forbedring af antistofbaserede fusionsproteiners serumhalveringstid
|
|
ATE319737T1
(de)
*
|
2000-04-21 |
2006-03-15 |
Amgen Inc |
Peptidderivate des apolipoproteins-a1/aii
|
|
US6667300B2
(en)
|
2000-04-25 |
2003-12-23 |
Icos Corporation |
Inhibitors of human phosphatidylinositol 3-kinase delta
|
|
US6677136B2
(en)
|
2000-05-03 |
2004-01-13 |
Amgen Inc. |
Glucagon antagonists
|
|
EP1280826B1
(en)
|
2000-05-12 |
2007-05-02 |
Amgen Inc. |
Polypeptides for inhibiting april-mediated b- and t-cell proliferation.
|
|
RU2272644C2
(ru)
|
2000-06-29 |
2006-03-27 |
Мерк Патент Гмбх |
Усиление иммунной реакции, медиатором которой является слитый протеин антитело-цитокин, при помощи комбинированного лечения агентами, увеличивающими поглощение иммуноцитокина
|
|
US6818216B2
(en)
|
2000-11-28 |
2004-11-16 |
Medimmune, Inc. |
Anti-RSV antibodies
|
|
US7179900B2
(en)
|
2000-11-28 |
2007-02-20 |
Medimmune, Inc. |
Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
|
|
EP2412384A1
(en)
|
2000-11-28 |
2012-02-01 |
MedImmune, LLC |
Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
|
|
US6855493B2
(en)
|
2000-11-28 |
2005-02-15 |
Medimmune, Inc. |
Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
|
|
US7658921B2
(en)
|
2000-12-12 |
2010-02-09 |
Medimmune, Llc |
Molecules with extended half-lives, compositions and uses thereof
|
|
AU2008201419C1
(en)
*
|
2000-12-12 |
2018-01-18 |
Board Of Regents, The University Of Texas System |
Molecules with extended half-lives, compositions and uses thereof
|
|
PT1355919E
(pt)
*
|
2000-12-12 |
2011-03-02 |
Medimmune Llc |
Moléculas com semivida longa, composições que as contêm e suas utilizações
|
|
AU2011253690C1
(en)
*
|
2000-12-12 |
2018-01-18 |
Board Of Regents, The University Of Texas System |
Molecules with extended half-lives, compositions and uses thereof
|
|
KR100900176B1
(ko)
|
2001-03-07 |
2009-06-02 |
메르크 파텐트 게엠베하 |
하이브리드 이소타입 항체 부분구조를 포함하는 단백질을위한 발현 기술
|
|
US6992174B2
(en)
|
2001-03-30 |
2006-01-31 |
Emd Lexigen Research Center Corp. |
Reducing the immunogenicity of fusion proteins
|
|
US7256257B2
(en)
|
2001-04-30 |
2007-08-14 |
Seattle Genetics, Inc. |
Pentapeptide compounds and uses related thereto
|
|
CA2446087C
(en)
|
2001-05-03 |
2013-06-18 |
Stephen D. Gillies |
Recombinant tumor specific antibody and use thereof
|
|
JP4516719B2
(ja)
|
2001-05-11 |
2010-08-04 |
アムジエン・インコーポレーテツド |
Ｔａｌｌ−１と結合するペプチド及び関連分子
|
|
US7138370B2
(en)
|
2001-10-11 |
2006-11-21 |
Amgen Inc. |
Specific binding agents of human angiopoietin-2
|
|
US7332474B2
(en)
|
2001-10-11 |
2008-02-19 |
Amgen Inc. |
Peptides and related compounds having thrombopoietic activity
|
|
BR0214650A
(pt)
|
2001-12-04 |
2005-05-03 |
Merck Patent Gmbh |
Imunocitoquinas com seletividade modulada
|
|
US7662925B2
(en)
|
2002-03-01 |
2010-02-16 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
|
US8188231B2
(en)
|
2002-09-27 |
2012-05-29 |
Xencor, Inc. |
Optimized FC variants
|
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
|
US20040028685A1
(en)
|
2002-05-10 |
2004-02-12 |
Kinch Michael S. |
EphA2 monoclonal antibodies and methods of use thereof
|
|
US7425618B2
(en)
|
2002-06-14 |
2008-09-16 |
Medimmune, Inc. |
Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
|
|
US7132100B2
(en)
|
2002-06-14 |
2006-11-07 |
Medimmune, Inc. |
Stabilized liquid anti-RSV antibody formulations
|
|
DK1545613T3
(da)
|
2002-07-31 |
2011-11-14 |
Seattle Genetics Inc |
Auristatinkonjugater og deres anvendelse til behandling af cancer, en autoimmun sygdom eller en infektiøs sygdom
|
|
US8530627B2
(en)
|
2002-08-14 |
2013-09-10 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US8187593B2
(en)
|
2002-08-14 |
2012-05-29 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US8946387B2
(en)
|
2002-08-14 |
2015-02-03 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US8968730B2
(en)
|
2002-08-14 |
2015-03-03 |
Macrogenics Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US20040136992A1
(en)
|
2002-08-28 |
2004-07-15 |
Burton Paul B. J. |
Compositions and method for treating cardiovascular disease
|
|
US6919426B2
(en)
|
2002-09-19 |
2005-07-19 |
Amgen Inc. |
Peptides and related molecules that modulate nerve growth factor activity
|
|
US7365168B2
(en)
|
2002-10-15 |
2008-04-29 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
US7217798B2
(en)
|
2003-10-15 |
2007-05-15 |
Pdl Biopharma, Inc. |
Alteration of Fc-fusion protein serum half-lives by mutagenesis
|
|
US7217797B2
(en)
|
2002-10-15 |
2007-05-15 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
US7361740B2
(en)
|
2002-10-15 |
2008-04-22 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
JP4494977B2
(ja)
|
2002-12-17 |
2010-06-30 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ｇｄ２に結合するマウス１４．１８抗体のヒト化抗体（ｈ１４．１８）およびそのｉｌ−２融合タンパク質
|
|
EP2368578A1
(en)
|
2003-01-09 |
2011-09-28 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant Fc regions and methods of using same
|
|
US7960512B2
(en)
|
2003-01-09 |
2011-06-14 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant Fc regions and methods of using same
|
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
|
US8388955B2
(en)
|
2003-03-03 |
2013-03-05 |
Xencor, Inc. |
Fc variants
|
|
US8084582B2
(en)
|
2003-03-03 |
2011-12-27 |
Xencor, Inc. |
Optimized anti-CD20 monoclonal antibodies having Fc variants
|
|
JP4685764B2
(ja)
*
|
2003-04-10 |
2011-05-18 |
アボット バイオセラピューティクス コーポレイション |
変異誘発による抗体のＦｃＲｎ結合親和力又は血清半減期の改変
|
|
EP1613273B1
(en)
|
2003-04-11 |
2012-06-13 |
MedImmune, LLC |
Recombinant il-9 antibodies and uses thereof
|
|
US9051373B2
(en)
|
2003-05-02 |
2015-06-09 |
Xencor, Inc. |
Optimized Fc variants
|
|
PT1624891E
(pt)
|
2003-05-06 |
2010-01-05 |
Syntonix Pharmaceuticals Inc |
Proteínas quiméricas de factor de coagulação-fc destinadas ao tratamento da hemofilia
|
|
EP1648935A2
(en)
|
2003-07-25 |
2006-04-26 |
Amgen Inc. |
Antagonists and agonists of ldcam and methods of use
|
|
NZ545776A
(en)
|
2003-08-22 |
2009-05-31 |
Biogen Idec Inc |
Improved antibodies having altered effector function and methods for making the same
|
|
US9714282B2
(en)
|
2003-09-26 |
2017-07-25 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
|
US8101720B2
(en)
|
2004-10-21 |
2012-01-24 |
Xencor, Inc. |
Immunoglobulin insertions, deletions and substitutions
|
|
CA2543484C
(en)
|
2003-10-27 |
2014-02-04 |
Amgen Inc. |
Modulation of immune response to an immunogen with ctla-4 and tnfbp
|
|
CN107213469A
(zh)
|
2003-11-06 |
2017-09-29 |
西雅图基因公司 |
能够与配体偶联的单甲基缬氨酸化合物
|
|
KR101135244B1
(ko)
|
2007-11-29 |
2012-04-24 |
한미사이언스 주식회사 |
인슐린 분비 펩타이드 결합체를 포함하는 비만 관련질환 치료용 조성물
|
|
JP2007531513A
(ja)
|
2003-11-13 |
2007-11-08 |
ハンミ ファーム．インダストリー カンパニー リミテッド |
薬物のキャリアとして有用なＩｇＧＦｃ断片およびその製造方法
|
|
US7371381B2
(en)
|
2003-12-12 |
2008-05-13 |
Amgen Inc. |
Anti-galanin antibodies and uses thereof
|
|
DK1699822T3
(da)
|
2003-12-30 |
2008-08-04 |
Merck Patent Gmbh |
IL-7-fusionsproteiner med antistofdele, fremstilling deraf og anvendelse deraf
|
|
WO2005063808A1
(en)
|
2003-12-31 |
2005-07-14 |
Merck Patent Gmbh |
Fc-ERYTHROPOIETIN FUSION PROTEIN WITH IMPROVED PHARMACOKINETICS
|
|
DK2311873T3
(en)
|
2004-01-07 |
2018-11-26 |
Novartis Vaccines & Diagnostics Inc |
M-CSF-SPECIFIC MONOCLONAL ANTIBODY AND APPLICATIONS THEREOF
|
|
ATE443724T1
(de)
|
2004-01-22 |
2009-10-15 |
Merck Patent Gmbh |
Antikrebs-antikörper mit reduzierter komplementfixierung
|
|
CA2553187A1
(en)
|
2004-01-28 |
2005-08-11 |
Syntonix Pharmaceuticals, Inc. |
Heterodimeric follicle stimulating hormone-fc (fsh-fc) fusion proteins for the treatment of infertility
|
|
US7276585B2
(en)
|
2004-03-24 |
2007-10-02 |
Xencor, Inc. |
Immunoglobulin variants outside the Fc region
|
|
MXPA06012601A
(es)
|
2004-05-10 |
2007-05-10 |
Macrogenics Inc |
Anticuerpos especificos de fcy riib humanizados y metodos de uso de los mismos.
|
|
PL1761540T3
(pl)
|
2004-05-13 |
2017-06-30 |
Icos Corporation |
Chinazolinony jako inhibitory ludzkiej kinazy 3-fosfatydyloinozytolu delta
|
|
KR101699142B1
(ko)
|
2004-06-18 |
2017-01-23 |
암브룩스, 인코포레이티드 |
신규 항원-결합 폴리펩티드 및 이의 용도
|
|
CA2572765C
(en)
|
2004-07-08 |
2013-05-21 |
Amgen Inc. |
Compound having improved bioefficiency when administered in a multidose regimen
|
|
US20150010550A1
(en)
|
2004-07-15 |
2015-01-08 |
Xencor, Inc. |
OPTIMIZED Fc VARIANTS
|
|
EP2399936A3
(en)
|
2004-07-26 |
2012-02-22 |
Biogen Idec MA Inc. |
Anti-CD154 antibodies
|
|
ES2426817T3
(es)
|
2004-08-04 |
2013-10-25 |
Mentrik Biotech, Llc |
Regiones Fc variantes
|
|
US7700720B2
(en)
|
2004-09-21 |
2010-04-20 |
Medimmune, Llc |
Antibodies against and methods for producing vaccines for respiratory syncytial virus
|
|
CN101103045B
(zh)
|
2004-09-24 |
2015-11-25 |
安姆根有限公司 |
修饰的Fc分子
|
|
EP2422811A2
(en)
|
2004-10-27 |
2012-02-29 |
MedImmune, LLC |
Modulation of antibody specificity by tailoring the affinity to cognate antigens
|
|
US7632497B2
(en)
|
2004-11-10 |
2009-12-15 |
Macrogenics, Inc. |
Engineering Fc Antibody regions to confer effector function
|
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
EP3505191A1
(en)
|
2004-11-12 |
2019-07-03 |
Seattle Genetics, Inc. |
Auristatins having an aminobenzoic acid unit at the n terminus
|
|
US8367805B2
(en)
|
2004-11-12 |
2013-02-05 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
DK1817340T3
(da)
|
2004-11-12 |
2012-08-13 |
Xencor Inc |
Fc-varianter med ændret binding til fcrn
|
|
US8546543B2
(en)
|
2004-11-12 |
2013-10-01 |
Xencor, Inc. |
Fc variants that extend antibody half-life
|
|
ATE465176T1
(de)
|
2004-12-09 |
2010-05-15 |
Merck Patent Gmbh |
Il-7-varianten mit reduzierter immunogenität
|
|
KR20130105885A
(ko)
|
2005-01-05 |
2013-09-26 |
에프-스타 비오테크놀로기쉐 포르슝스 운드 엔트비클룽스게스.엠.베.하. |
상보성 결정부위와 다른 분자의 부위에서 처리된 결합성을 갖는 합성 면역글로불린 영역
|
|
KR100754667B1
(ko)
|
2005-04-08 |
2007-09-03 |
한미약품 주식회사 |
비펩타이드성 중합체로 개질된 면역글로불린 Ｆｃ 단편 및이를 포함하는 약제학적 조성물
|
|
US9284375B2
(en)
|
2005-04-15 |
2016-03-15 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
US11254748B2
(en)
|
2005-04-15 |
2022-02-22 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
EP3479844B1
(en)
|
2005-04-15 |
2023-11-22 |
MacroGenics, Inc. |
Covalent diabodies and uses thereof
|
|
US9963510B2
(en)
|
2005-04-15 |
2018-05-08 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
US7833979B2
(en)
|
2005-04-22 |
2010-11-16 |
Amgen Inc. |
Toxin peptide therapeutic agents
|
|
KR101446989B1
(ko)
|
2005-05-06 |
2014-10-15 |
지모제넥틱스, 인코포레이티드 |
Ｉｌ-31 단클론성 항체 및 사용법
|
|
EP2163562B1
(en)
|
2005-06-21 |
2013-09-18 |
XOMA Technology Ltd. |
IL-1beta binding antibodies and fragments thereof
|
|
AU2006261920A1
(en)
|
2005-06-23 |
2007-01-04 |
Medimmune, Llc |
Antibody formulations having optimized aggregation and fragmentation profiles
|
|
WO2007008603A1
(en)
|
2005-07-07 |
2007-01-18 |
Seattle Genetics, Inc. |
Monomethylvaline compounds having phenylalanine side-chain modifications at the c-terminus
|
|
US7557190B2
(en)
|
2005-07-08 |
2009-07-07 |
Xencor, Inc. |
Optimized proteins that target Ep-CAM
|
|
DK1912671T3
(da)
|
2005-07-18 |
2017-11-27 |
Seattle Genetics Inc |
Beta-glucuronid-linker-lægemiddelkonjugater
|
|
JP5457671B2
(ja)
|
2005-07-28 |
2014-04-02 |
ノバルティス アーゲー |
Ｍ−ｃｓｆ特異的モノクローナル抗体およびその使用
|
|
CA2618681C
(en)
|
2005-08-10 |
2015-10-27 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant fc regions and methods of using same
|
|
US8008453B2
(en)
|
2005-08-12 |
2011-08-30 |
Amgen Inc. |
Modified Fc molecules
|
|
AU2006299429B2
(en)
|
2005-10-03 |
2012-02-23 |
Xencor, Inc. |
Fc variants with optimized Fc receptor binding properties
|
|
US7973136B2
(en)
|
2005-10-06 |
2011-07-05 |
Xencor, Inc. |
Optimized anti-CD30 antibodies
|
|
NZ597082A
(en)
|
2005-10-13 |
2013-11-29 |
Human Genome Sciences Inc |
Methods and Compositions for Use in Treatment of Patients with Autoantibody Positive Diseases
|
|
TW200732350A
(en)
|
2005-10-21 |
2007-09-01 |
Amgen Inc |
Methods for generating monovalent IgG
|
|
AU2006340750B2
(en)
|
2005-11-28 |
2013-03-07 |
Zymogenetics, Inc. |
IL-21 antagonists
|
|
US7981414B2
(en)
|
2005-12-20 |
2011-07-19 |
Cephalon Australia Pty Ltd |
Anti-inflammatory dAb
|
|
WO2007102946A2
(en)
|
2006-01-23 |
2007-09-13 |
Amgen Inc. |
Crystalline polypeptides
|
|
EP1987064A4
(en)
|
2006-02-01 |
2010-04-07 |
Arana Therapeutics Ltd |
DOMAIN ANTIBODY CONSTRUCT
|
|
US8278421B2
(en)
|
2006-03-20 |
2012-10-02 |
Xoma Techolology Ltd. |
Human antibodies specific for gastrin materials and methods
|
|
IN2014DN10515A
(enExample)
|
2006-03-31 |
2015-08-21 |
Chugai Pharmaceutical Co Ltd |
|
|
JO3324B1
(ar)
|
2006-04-21 |
2019-03-13 |
Amgen Inc |
مركبات علاجية مجففة بالتبريد تتعلق بالعصارة الهضمية
|
|
TWI395754B
(zh)
|
2006-04-24 |
2013-05-11 |
Amgen Inc |
人類化之ｃ-ｋｉｔ抗體
|
|
CA2650730A1
(en)
|
2006-04-27 |
2007-11-08 |
Pikamab, Inc. |
Methods and compositions for antibody therapy
|
|
US7786270B2
(en)
|
2006-05-26 |
2010-08-31 |
Macrogenics, Inc. |
Humanized FcγRIIB-specific antibodies and methods of use thereof
|
|
SG10201504662WA
(en)
|
2006-06-14 |
2015-07-30 |
Macrogenics Inc |
Methods For The Treatment Of Autoimmune Disorders Using Immunosuppressive Monoclonal Antibodies With Reduced Toxicity
|
|
US7981425B2
(en)
|
2006-06-19 |
2011-07-19 |
Amgen Inc. |
Thrombopoietic compounds
|
|
US7932055B2
(en)
|
2006-06-22 |
2011-04-26 |
Novo Nordisk A/S |
Soluble heterodimeric CD94/NKG2 receptors fusion proteins
|
|
EP2032159B1
(en)
|
2006-06-26 |
2015-01-07 |
MacroGenics, Inc. |
Combination of fcgammariib antibodies and cd20-specific antibodies and methods of use thereof
|
|
PT2029173T
(pt)
|
2006-06-26 |
2016-11-02 |
Macrogenics Inc |
Anticorpos específicos fc rib e seus métodos de uso
|
|
ES2376396T3
(es)
|
2006-06-26 |
2012-03-13 |
Amgen Inc. |
Método para tratar aterosclerosis.
|
|
AT503861B1
(de)
|
2006-07-05 |
2008-06-15 |
F Star Biotech Forsch & Entw |
Verfahren zur manipulation von t-zell-rezeptoren
|
|
AT503889B1
(de)
|
2006-07-05 |
2011-12-15 |
Star Biotechnologische Forschungs Und Entwicklungsges M B H F |
Multivalente immunglobuline
|
|
AT503902B1
(de)
|
2006-07-05 |
2008-06-15 |
F Star Biotech Forsch & Entw |
Verfahren zur manipulation von immunglobulinen
|
|
EP2064244B1
(en)
|
2006-08-03 |
2019-06-05 |
MedImmune Limited |
ANTIBODIES DIRECTED TO alphaVbeta6 AND USES THEREOF
|
|
CL2007002225A1
(es)
|
2006-08-03 |
2008-04-18 |
Astrazeneca Ab |
Agente de union especifico para un receptor del factor de crecimiento derivado de plaquetas (pdgfr-alfa); molecula de acido nucleico que lo codifica; vector y celula huesped que la comprenden; conjugado que comprende al agente; y uso del agente de un
|
|
EP2057193B1
(en)
|
2006-08-04 |
2013-12-18 |
Novartis AG |
Ephb3-specific antibody and uses thereof
|
|
WO2008019290A2
(en)
|
2006-08-04 |
2008-02-14 |
Astrazeneca Ab |
Human antibodies to erbb 2
|
|
JP5825756B2
(ja)
|
2006-08-14 |
2015-12-02 |
ゼンコー・インコーポレイテッドＸｅｎｃｏｒ、 Ｉｎｃ． |
Ｃｄ１９を標的とする最適化抗体
|
|
HRP20140081T1
(hr)
|
2006-08-18 |
2014-03-28 |
Novartis Ag |
Prlr-specifiäśna antitijela i njihova uporaba
|
|
EA021255B1
(ru)
|
2006-08-28 |
2015-05-29 |
Киова Хакко Кирин Ко., Лимитед |
Антагонистические моноклональные антитела человека, специфичные в отношении light человека
|
|
RU2009111884A
(ru)
|
2006-09-01 |
2010-10-10 |
Займоджинетикс, Инк. (Us) |
Последовательности вариабельных областей моноклональных антител против il-31 и способы использования
|
|
WO2008036688A2
(en)
|
2006-09-18 |
2008-03-27 |
Xencor, Inc. |
Optimized antibodies that target hm1.24
|
|
EP2407548A1
(en)
|
2006-10-16 |
2012-01-18 |
MedImmune, LLC |
Molecules with reduced half-lives, compositions and uses thereof
|
|
PE20081140A1
(es)
|
2006-10-25 |
2008-09-22 |
Amgen Inc |
Agentes terapeuticos a base de peptidos derivados de toxinas
|
|
HU0700534D0
(en)
|
2006-11-24 |
2007-10-29 |
Mezoegazdasagi Biotechnologiai |
Transgenic animal with enhanced immune response and method for the preparation thereof
|
|
DK2099823T4
(da)
|
2006-12-01 |
2022-05-09 |
Seagen Inc |
Målbindingsmiddelvarianter og anvendelser deraf
|
|
CA2672120A1
(en)
|
2006-12-07 |
2008-06-12 |
Novartis Ag |
Antagonistic antibodies against ephb3
|
|
WO2008140603A2
(en)
|
2006-12-08 |
2008-11-20 |
Macrogenics, Inc. |
METHODS FOR THE TREATMENT OF DISEASE USING IMMUNOGLOBULINS HAVING FC REGIONS WITH ALTERED AFFINITIES FOR FCγR ACTIVATING AND FCγR INHIBITING
|
|
US7695718B2
(en)
|
2006-12-20 |
2010-04-13 |
Xoma Technology Ltd. |
Methods for the treatment of IL-1β related diseases
|
|
JP2008169195A
(ja)
|
2007-01-05 |
2008-07-24 |
Hanmi Pharmaceutical Co Ltd |
キャリア物質を用いたインスリン分泌ペプチド薬物結合体
|
|
AU2008232903B9
(en)
|
2007-03-30 |
2013-09-05 |
Medimmune Llc |
Antibodies with decreased deamidation profiles
|
|
ES2540807T3
(es)
|
2007-05-04 |
2015-07-13 |
Technophage, Investigação E Desenvolvimento Em Biotecnologia, Sa |
Dominios variables de anticuerpos de conejo modificados por ingeniería genética y usos de los mismos
|
|
ES2642008T3
(es)
|
2007-05-11 |
2017-11-14 |
Altor Bioscience Corporation |
Moléculas de fusión y variantes de IL-15
|
|
HUE026728T2
(en)
|
2007-05-14 |
2016-06-28 |
Medimmune Llc |
A method for reducing eosinophil levels
|
|
JP5591691B2
(ja)
|
2007-05-22 |
2014-09-17 |
アムジエン・インコーポレーテツド |
生物活性を有する融合タンパク質を作製するための組成物及び方法
|
|
DK2176298T3
(en)
|
2007-05-30 |
2018-02-12 |
Xencor Inc |
Methods and compositions for inhibiting CD32B-expressing cells
|
|
EP1997830A1
(en)
|
2007-06-01 |
2008-12-03 |
AIMM Therapeutics B.V. |
RSV specific binding molecules and means for producing them
|
|
ES2627223T3
(es)
|
2007-06-26 |
2017-07-27 |
F-Star Biotechnologische Forschungs- Und Entwicklungsges.M.B.H |
Presentación de agentes de unión
|
|
WO2009014708A2
(en)
|
2007-07-23 |
2009-01-29 |
Cell Genesys, Inc. |
Pd-1 antibodies in combination with a cytokine-secreting cell and methods of use thereof
|
|
MY159075A
(en)
|
2007-07-26 |
2016-12-15 |
Amgen Inc |
Modified lecithin-cholesterol acyltransferase enzymes
|
|
WO2009018386A1
(en)
|
2007-07-31 |
2009-02-05 |
Medimmune, Llc |
Multispecific epitope binding proteins and uses thereof
|
|
PE20140196A1
(es)
|
2007-08-09 |
2014-03-19 |
Boehringer Ingelheim Int |
Anticuerpos anti-cd37
|
|
ES2672769T3
(es)
|
2007-08-29 |
2018-06-18 |
Sanofi |
Anticuerpos anti-CXCR5 humanizados, derivados de los mismos y sus usos
|
|
JP5592792B2
(ja)
|
2007-09-26 |
2014-09-17 |
ユセベ ファルマ ソシエテ アノニム |
二重特異性抗体の融合体
|
|
MX336725B
(es)
|
2007-09-26 |
2016-01-28 |
Chugai Pharmaceutical Co Ltd |
Metodo de modificacion del punto isoelectrico de anticuerpos medinate la sustitucion de aminoacidos en region de determinacion de complementariedad (cdr).
|
|
EP2050764A1
(en)
|
2007-10-15 |
2009-04-22 |
sanofi-aventis |
Novel polyvalent bispecific antibody format and uses thereof
|
|
LT2796466T
(lt)
|
2007-12-07 |
2018-02-26 |
Zymogenetics, Inc. |
Humanizuotų antikūnų molekulės, specifinės il-31 atžvilgiu
|
|
EP2217268B1
(en)
|
2007-12-07 |
2016-05-04 |
ZymoGenetics, Inc. |
Anti-human il-21 monoclonal antibodies
|
|
US8795667B2
(en)
|
2007-12-19 |
2014-08-05 |
Macrogenics, Inc. |
Compositions for the prevention and treatment of smallpox
|
|
HRP20141194T1
(hr)
|
2007-12-20 |
2015-04-24 |
Xoma (Us) Llc |
Postupci lijeäśenja gihta
|
|
EP2261254A3
(en)
|
2007-12-21 |
2011-04-13 |
Amgen, Inc |
Anti-amyloid antibodies and uses thereof
|
|
PL2808343T3
(pl)
|
2007-12-26 |
2019-11-29 |
Xencor Inc |
Warianty Fc ze zmienionym wiązaniem do FcRn
|
|
BRPI0907046A2
(pt)
|
2008-01-18 |
2015-07-28 |
Medimmune Llc |
Anticorpo de cisteína engenheirada, ácido nucleico isolado, vetor, célula hospedeira, conjugado de anticorpo, composição farmacêutica, métodos de detecção de câncer, doenças ou distúrbios autoimunes, inflamatórios ou infecciosos em um indivíduo e de inibição de proliferação de uma célula alvo
|
|
US12492253B1
(en)
|
2008-02-25 |
2025-12-09 |
Xencor, Inc. |
Anti-human C5 antibodies
|
|
DK2265283T3
(da)
|
2008-03-18 |
2014-10-20 |
Seattle Genetics Inc |
Auristatin-lægemiddel-linker-konjugater
|
|
PL2247304T3
(pl)
|
2008-04-02 |
2017-01-31 |
Macrogenics, Inc. |
Przeciwciała specyficzne wobec HER2/neu oraz sposoby ich zastosowania
|
|
US8669349B2
(en)
|
2008-04-02 |
2014-03-11 |
Macrogenics, Inc. |
BCR-complex-specific antibodies and methods of using same
|
|
TWI700293B
(zh)
|
2008-04-11 |
2020-08-01 |
日商中外製藥股份有限公司 |
重複結合複數個抗原的抗體
|
|
AU2009238605B2
(en)
*
|
2008-04-25 |
2014-11-06 |
Biogen Idec Hemophilia Inc. |
Antibodies against FcRn and use thereof
|
|
EP2113255A1
(en)
|
2008-05-02 |
2009-11-04 |
f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. |
Cytotoxic immunoglobulin
|
|
EA024751B8
(ru)
|
2008-06-04 |
2020-01-31 |
Амген Инк. |
Мутанты fgf21 и их применение
|
|
EP2307456B1
(en)
|
2008-06-27 |
2014-10-15 |
Amgen Inc. |
Ang-2 inhibition to treat multiple sclerosis
|
|
PY09026846A
(es)
|
2008-08-05 |
2015-09-01 |
Novartis Ag |
Composiciones y métodos para anticuerpos que se dirigen a la proteína de complemento c5
|
|
CN102282172B
(zh)
|
2008-09-07 |
2014-02-19 |
台湾醣联生技医药股份有限公司 |
抗伸展的ⅰ型鞘糖脂抗体、其衍生物以及用途
|
|
EP2344536A1
(en)
|
2008-09-19 |
2011-07-20 |
MedImmune, LLC |
Antibodies directed to dll4 and uses thereof
|
|
EP3524620A1
(en)
*
|
2008-10-14 |
2019-08-14 |
Genentech, Inc. |
Immunoglobulin variants and uses thereof
|
|
BRPI0921845A2
(pt)
|
2008-11-12 |
2019-09-17 |
Medimmune Llc |
formulação aquosa estéril estável, forma de dosagem unitária farmacêutica, seringa pré-carregada, e, métodos para tratar uma doença ou distúrbio, para tratar ou prevenir rejeição, para esgotar células t que expressam icos em um paciente humano, e para interromper arquitetura central germinal em um órgão linfóide secundário de um primata
|
|
NZ631024A
(en)
|
2008-11-13 |
2016-04-29 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
|
US9492449B2
(en)
|
2008-11-13 |
2016-11-15 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
|
US8775090B2
(en)
|
2008-12-12 |
2014-07-08 |
Medimmune, Llc |
Crystals and structure of a human IgG Fc variant with enhanced FcRn binding
|
|
JP2012513194A
(ja)
|
2008-12-23 |
2012-06-14 |
アストラゼネカ アクチボラグ |
α５β１に向けられた標的結合剤およびその使用
|
|
WO2010087927A2
(en)
|
2009-02-02 |
2010-08-05 |
Medimmune, Llc |
Antibodies against and methods for producing vaccines for respiratory syncytial virus
|
|
WO2010108154A2
(en)
|
2009-03-20 |
2010-09-23 |
Amgen Inc. |
Selective and potent peptide inhibitors of kv1.3
|
|
SG174529A1
(en)
|
2009-03-24 |
2011-10-28 |
Gilead Calistoga Llc |
Atropisomers of2-purinyl-3-tolyl-quinazolinone derivatives and methods of use
|
|
PT2421536E
(pt)
|
2009-04-20 |
2015-10-20 |
Gilead Calistoga Llc |
Métodos de tratamento para tumores sólidos
|
|
EA030182B1
(ru)
|
2009-04-20 |
2018-07-31 |
Оксфорд Байотерепьютикс Лтд. |
Антитела, специфические для кадгерина-17
|
|
CA2759333A1
(en)
*
|
2009-04-22 |
2010-10-28 |
Merck Patent Gmbh |
Antibody fusion proteins with modified fcrn binding sites
|
|
SMT202400036T1
(it)
|
2009-05-05 |
2024-03-13 |
Amgen Inc |
Mutanti fgf21 e loro utilizzi
|
|
US20120052069A1
(en)
|
2009-05-05 |
2012-03-01 |
Amgen Inc |
Fgf21 mutants and uses thereof
|
|
US20120134984A1
(en)
|
2009-06-01 |
2012-05-31 |
Olga Lubman |
Molecules with extended half-lives and uses thereof
|
|
EP2443137B1
(en)
|
2009-06-15 |
2015-05-20 |
Biokine Therapeutics Ltd. |
Novel chemokine binding polypeptides capable of inhibiting the course of autoimmunity, inflammation and cancer
|
|
JP2012530498A
(ja)
|
2009-06-19 |
2012-12-06 |
メディミューン，エルエルシー |
プロテアーゼバリアント
|
|
WO2011005481A1
(en)
|
2009-06-22 |
2011-01-13 |
Medimmune, Llc |
ENGINEERED Fc REGIONS FOR SITE-SPECIFIC CONJUGATION
|
|
EP2456443A1
(en)
|
2009-07-21 |
2012-05-30 |
Gilead Calistoga LLC |
Treatment of liver disorders with pi3k inhibitors
|
|
US8840889B2
(en)
|
2009-08-13 |
2014-09-23 |
The Johns Hopkins University |
Methods of modulating immune function
|
|
ES2553440T3
(es)
|
2009-08-13 |
2015-12-09 |
Crucell Holland B.V. |
Anticuerpos contra el virus sincitial respiratorio humano (VSR) y método de uso
|
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
WO2011035205A2
(en)
|
2009-09-18 |
2011-03-24 |
Calmune Corporation |
Antibodies against candida, collections thereof and methods of use
|
|
US8926976B2
(en)
|
2009-09-25 |
2015-01-06 |
Xoma Technology Ltd. |
Modulators
|
|
AU2010298036B2
(en)
|
2009-09-25 |
2015-05-21 |
Xoma Technology Ltd. |
Screening methods
|
|
GB201005063D0
(en)
|
2010-03-25 |
2010-05-12 |
Ucb Pharma Sa |
Biological products
|
|
US8568726B2
(en)
|
2009-10-06 |
2013-10-29 |
Medimmune Limited |
RSV specific binding molecule
|
|
CN102666874B
(zh)
|
2009-10-07 |
2016-06-01 |
宏观基因有限公司 |
由于岩藻糖基化程度的改变而表现出改善的效应子功能的含Fc区的多肽及其使用方法
|
|
US20120231004A1
(en)
|
2009-10-13 |
2012-09-13 |
Oxford Biotherapeutic Ltd. |
Antibodies
|
|
JP2013509874A
(ja)
|
2009-11-04 |
2013-03-21 |
エラスムス ユニバーシティ メディカル センター ロッテルダム |
新脈管形成を調節する為の新規化合物及びこれらの化合物を使用する処置方法
|
|
US20120231006A1
(en)
|
2009-11-20 |
2012-09-13 |
Amgen Inc. |
Anti-orai1 antigen binding proteins and uses thereof
|
|
PT2504364T
(pt)
|
2009-11-24 |
2017-11-14 |
Medimmune Ltd |
Agentes de ligação direcionados contra b7-h1
|
|
UA109888C2
(uk)
|
2009-12-07 |
2015-10-26 |
|
ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
|
|
KR101312829B1
(ko)
|
2009-12-30 |
2013-09-27 |
한화엘앤씨 주식회사 |
ＨＯ-1 유전자 및 ＴＮＦＲ1-Ｆｃ 유전자를 동시에 발현하는 형질전환 돼지 및 그의 제조 방법
|
|
US8362210B2
(en)
|
2010-01-19 |
2013-01-29 |
Xencor, Inc. |
Antibody variants with enhanced complement activity
|
|
DK2542256T3
(da)
|
2010-03-04 |
2019-08-26 |
Macrogenics Inc |
Antistoffer reagerende med b7-h3, immunologisk aktive fragmenter deraf og anvendelser deraf
|
|
PH12012501751A1
(en)
|
2010-03-04 |
2012-11-12 |
Macrogenics Inc |
Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
|
|
AR081755A1
(es)
|
2010-04-02 |
2012-10-17 |
Hanmi Holdings Co Ltd |
Formulacion de accion prolongada de la hormona estimuladora de los foliculos donde se usa un fragmento de inmunoglobulina, metodo de preparacion y metodo para tratar a un sujeto que sufre un trastorno reproductivo
|
|
AR081066A1
(es)
|
2010-04-02 |
2012-06-06 |
Hanmi Holdings Co Ltd |
Conjugado de insulina donde se usa un fragmento de inmunoglobulina
|
|
AR080993A1
(es)
|
2010-04-02 |
2012-05-30 |
Hanmi Holdings Co Ltd |
Formulacion de accion prolongada de interferon beta donde se usa un fragmento de inmunoglobulina
|
|
US20130101590A1
(en)
|
2010-04-09 |
2013-04-25 |
Heather A. Arnett |
Btnl9 proteins, nucleic acids, and antibodies and uses thereof
|
|
US9517264B2
(en)
|
2010-04-15 |
2016-12-13 |
Amgen Inc. |
Human FGF receptor and β-Klotho binding proteins
|
|
EA201291180A1
(ru)
|
2010-05-06 |
2013-05-30 |
Новартис Аг |
Композиции и способы применения терапевтических антител против белка, родственного рецептору липопротеинов низкой плотности 6 (lrp6)
|
|
PH12012502193A1
(en)
|
2010-05-06 |
2021-08-09 |
Novartis Ag |
Compositions and methods of use for therapeutic low density lipoprotein - related protein 6 (lrp6) multivalent antibodies
|
|
KR101818274B1
(ko)
|
2010-05-27 |
2018-01-12 |
머크 샤프 앤드 돔 코포레이션 |
개선된 특성을 갖는 항체의 제조 방법
|
|
TWI627964B
(zh)
|
2010-07-09 |
2018-07-01 |
傑森疫苗防護公司 |
抗-人類呼吸道融合性病毒（ｒｓｖ）抗體及其使用方法
|
|
SG10201913700SA
(en)
|
2010-07-09 |
2020-03-30 |
Bioverativ Therapeutics Inc |
Factor ix polypeptides and methods of use thereof
|
|
KR101382593B1
(ko)
|
2010-07-21 |
2014-04-10 |
한미사이언스 주식회사 |
신규한 지속형 글루카곤 결합체 및 이를 포함하는 비만 예방 및 치료용 약학적 조성물
|
|
CA2807127C
(en)
|
2010-08-02 |
2019-02-12 |
Leslie S. Johnson |
Covalent diabodies and uses thereof
|
|
WO2012019061A2
(en)
|
2010-08-05 |
2012-02-09 |
Stem Centrx, Inc. |
Novel effectors and methods of use
|
|
PL2606070T3
(pl)
|
2010-08-20 |
2017-06-30 |
Novartis Ag |
Przeciwciała dla receptora epidermalnego czynnika wzrostu 3 (her3)
|
|
CA2809369A1
(en)
|
2010-08-27 |
2012-03-01 |
Stem Centrx, Inc. |
Notum protein modulators and methods of use
|
|
BR112013005116A2
(pt)
|
2010-09-03 |
2019-09-24 |
Stem Centrx Inc |
moduladores e métodos de uso
|
|
US11053299B2
(en)
|
2010-09-21 |
2021-07-06 |
Immunity Bio, Inc. |
Superkine
|
|
EP3851459B1
(en)
|
2010-09-21 |
2024-05-01 |
Altor BioScience, LLC |
Multimeric il-15 soluble fusion molecules and methods of making and using same
|
|
CN103339145A
(zh)
|
2010-09-22 |
2013-10-02 |
安姆根有限公司 |
运载体免疫球蛋白及其用途
|
|
UA112062C2
(uk)
|
2010-10-04 |
2016-07-25 |
Бьорінгер Інгельхайм Інтернаціональ Гмбх |
Cd33-зв'язувальний агент
|
|
AU2011325833C1
(en)
|
2010-11-05 |
2017-07-13 |
Zymeworks Bc Inc. |
Stable heterodimeric antibody design with mutations in the Fc domain
|
|
US9023791B2
(en)
|
2010-11-19 |
2015-05-05 |
Novartis Ag |
Fibroblast growth factor 21 mutations
|
|
US20130245233A1
(en)
|
2010-11-24 |
2013-09-19 |
Ming Lei |
Multispecific Molecules
|
|
KR102568454B1
(ko)
|
2010-11-30 |
2023-08-18 |
추가이 세이야쿠 가부시키가이샤 |
복수 분자의 항원에 반복해서 결합하는 항원 결합 분자
|
|
MX356400B
(es)
|
2010-12-08 |
2018-05-28 |
Abbvie Stemcentrx Llc |
Moduladores novedosos y metodos de uso.
|
|
JP6147670B2
(ja)
|
2010-12-22 |
2017-06-14 |
テバ・ファーマシューティカルズ・オーストラリア・ピーティワイ・リミテッド |
改善された半減期を有する修飾された抗体
|
|
WO2012092539A2
(en)
|
2010-12-31 |
2012-07-05 |
Takeda Pharmaceutical Company Limited |
Antibodies to dll4 and uses thereof
|
|
KR101276801B1
(ko)
|
2011-01-21 |
2013-06-19 |
한화엘앤씨 주식회사 |
ｓＴＮＦＲ1-Ｆｃ 유전자를 발현하는 형질전환 돼지 및 이의 용도
|
|
AR085091A1
(es)
|
2011-01-26 |
2013-09-11 |
Kolltan Pharmaceuticals Inc |
Anticuerpos anti-kit y sus usos
|
|
US10689447B2
(en)
|
2011-02-04 |
2020-06-23 |
Genentech, Inc. |
Fc variants and methods for their production
|
|
SA112330278B1
(ar)
|
2011-02-18 |
2015-10-09 |
ستيم سينتركس، انك. |
مواد ضابطة جديدة وطرق للاستخدام
|
|
EP3604330A1
(en)
|
2011-02-25 |
2020-02-05 |
Chugai Seiyaku Kabushiki Kaisha |
Fcgammariib-specific fc antibody
|
|
SG10201601789TA
(en)
|
2011-03-16 |
2016-04-28 |
Amgen Inc |
Potent And Selective Inhibitors Of Nav1.3 And Nav1.7
|
|
TWI719112B
(zh)
|
2011-03-16 |
2021-02-21 |
賽諾菲公司 |
雙重ｖ區類抗體蛋白質之用途
|
|
BR112013024574B1
(pt)
|
2011-03-29 |
2022-08-09 |
Roche Glycart Ag |
Anticorpo e uso do anticorpo
|
|
EP2697257B1
(en)
|
2011-04-13 |
2016-10-19 |
Bristol-Myers Squibb Company |
Fc fusion proteins comprising novel linkers or arrangements
|
|
WO2015067913A1
(en)
|
2013-11-07 |
2015-05-14 |
Diagnodus Limited |
Biomarkers
|
|
WO2012162068A2
(en)
|
2011-05-21 |
2012-11-29 |
Macrogenics, Inc. |
Deimmunized serum-binding domains and their use for extending serum half-life
|
|
WO2012162277A1
(en)
|
2011-05-25 |
2012-11-29 |
Merck Sharp & Dohme Corp. |
METHOD FOR PREPARING Fc-CONTAINING POLYPEPTIDES HAVING IMPROVED PROPERTIES
|
|
UA113626C2
(xx)
|
2011-06-02 |
2017-02-27 |
|
Композиція для лікування діабету, що містить кон'югат інсуліну тривалої дії та кон'югат інсулінотропного пептиду тривалої дії
|
|
EP3954704A1
(en)
|
2011-06-03 |
2022-02-16 |
XOMA Technology Ltd. |
Antibodies specific for tgf-beta
|
|
US9244074B2
(en)
|
2011-06-07 |
2016-01-26 |
University Of Hawaii |
Biomarker of asbestos exposure and mesothelioma
|
|
WO2012170742A2
(en)
|
2011-06-07 |
2012-12-13 |
University Of Hawaii |
Treatment and prevention of cancer with hmgb1 antagonists
|
|
HRP20181591T1
(hr)
|
2011-06-10 |
2018-11-30 |
Hanmi Science Co., Ltd. |
Novi derivati oksintomodulina i farmaceutski pripravci za liječenje pretilosti koji ih sadrže
|
|
WO2012172495A1
(en)
|
2011-06-14 |
2012-12-20 |
Novartis Ag |
Compositions and methods for antibodies targeting tem8
|
|
AU2012270366C1
(en)
|
2011-06-17 |
2017-07-13 |
Hanmi Science Co., Ltd. |
A conjugate comprising oxyntomodulin and an immunoglobulin fragment, and use thereof
|
|
ES2640960T3
(es)
|
2011-06-28 |
2017-11-07 |
Oxford Biotherapeutics Ltd. |
Anticuerpos para ADP-ribosil ciclasa 2
|
|
US9890218B2
(en)
|
2011-06-30 |
2018-02-13 |
Chugai Seiyaku Kabushiki Kaisha |
Heterodimerized polypeptide
|
|
CN103930134B
(zh)
|
2011-07-18 |
2016-12-21 |
阿茨生物股份有限公司 |
长效促黄体激素(lh)化合物
|
|
GB201112429D0
(en)
|
2011-07-19 |
2011-08-31 |
Glaxo Group Ltd |
Antigen-binding proteins with increased FcRn binding
|
|
US20130058947A1
(en)
|
2011-09-02 |
2013-03-07 |
Stem Centrx, Inc |
Novel Modulators and Methods of Use
|
|
CA2847837A1
(en)
|
2011-09-05 |
2013-03-14 |
Hanmi Science Co., Ltd. |
A pharmaceutical composition for treating cancer, comprising interferon alpha conjugate
|
|
UY34347A
(es)
|
2011-09-26 |
2013-04-30 |
Novartis Ag |
Proteínas de función dual para tratar trastornos metabólicos
|
|
UY34346A
(es)
|
2011-09-26 |
2013-04-30 |
Novartis Ag |
Proteínas de fusión para tratar trastornos metabólicos
|
|
KR20140076593A
(ko)
|
2011-09-30 |
2014-06-20 |
추가이 세이야쿠 가부시키가이샤 |
항원의 소실을 촉진시키는 항원 결합 분자
|
|
JP6322411B2
(ja)
|
2011-09-30 |
2018-05-09 |
中外製薬株式会社 |
複数の生理活性を有する抗原の消失を促進する抗原結合分子
|
|
TW201817745A
(zh)
|
2011-09-30 |
2018-05-16 |
日商中外製藥股份有限公司 |
具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子
|
|
EP2760471B9
(en)
|
2011-09-30 |
2017-07-19 |
Dana-Farber Cancer Institute, Inc. |
Therapeutic peptides
|
|
US9220774B2
(en)
|
2011-11-01 |
2015-12-29 |
Bionomics Inc. |
Methods of treating cancer by administering anti-GPR49 antibodies
|
|
WO2013067054A1
(en)
|
2011-11-01 |
2013-05-10 |
Bionomics, Inc. |
Antibodies and methods of treating cancer
|
|
WO2013067060A1
(en)
|
2011-11-01 |
2013-05-10 |
Bionomics, Inc. |
Anti-gpr49 antibodies
|
|
US10598653B2
(en)
|
2011-11-01 |
2020-03-24 |
Bionomics Inc. |
Methods of blocking cancer stem cell growth
|
|
AU2012332021B8
(en)
|
2011-11-04 |
2017-10-12 |
Zymeworks Bc Inc. |
Stable heterodimeric antibody design with mutations in the Fc domain
|
|
SG11201401717VA
(en)
|
2011-11-04 |
2014-05-29 |
Novartis Ag |
Low density lipoprotein-related protein 6 (lrp6) - half life extender constructs
|
|
KR20130049671A
(ko)
|
2011-11-04 |
2013-05-14 |
한미사이언스 주식회사 |
생리활성 폴리펩타이드 결합체 제조 방법
|
|
SI2776466T1
(sl)
|
2011-11-11 |
2017-12-29 |
Ucb Biopharma Sprl |
Protitelesa, ki se vežejo na albumin in njihovi vezavni fragmenti
|
|
CN104185477B
(zh)
|
2011-11-17 |
2017-05-24 |
辉瑞公司 |
细胞毒性肽及其抗体‑药物缀合物
|
|
BR112014013081A2
(pt)
|
2011-11-30 |
2020-10-20 |
Chugai Seiyaku Kabushiki Kaisha |
veículo contendo fármaco em célula para formação de um complexo imune
|
|
AU2012349735B2
(en)
|
2011-12-05 |
2016-05-19 |
Novartis Ag |
Antibodies for epidermal growth factor receptor 3 (HER3)
|
|
US20130273029A1
(en)
|
2011-12-05 |
2013-10-17 |
Novartis Ag |
Antibodies for epidermal growth factor receptor 3 (her3) directed to domain ii of her3
|
|
EP3050900A1
(en)
|
2011-12-19 |
2016-08-03 |
Xoma (Us) Llc |
Methods for treating acne
|
|
PE20150159A1
(es)
|
2011-12-21 |
2015-02-08 |
Novartis Ag |
Composiciones y metodos para anticuerpos que actuan sobre el factor p
|
|
JP2015502397A
(ja)
|
2011-12-23 |
2015-01-22 |
ファイザー・インク |
部位特異的コンジュゲーションのための操作された抗体定常領域、ならびにそのための方法および使用
|
|
KR101895047B1
(ko)
|
2011-12-30 |
2018-09-06 |
한미사이언스 주식회사 |
면역글로불린 단편을 이용한 위치 특이적 글루카곤 유사 펩타이드-2 약물 결합체
|
|
US10774132B2
(en)
|
2012-01-09 |
2020-09-15 |
The Scripps Research Instittue |
Ultralong complementarity determining regions and uses thereof
|
|
WO2013106489A1
(en)
|
2012-01-09 |
2013-07-18 |
The Scripps Research Institute |
Humanized antibodies with ultralong cdr3s
|
|
JP6226752B2
(ja)
|
2012-02-09 |
2017-11-08 |
中外製薬株式会社 |
抗体のＦｃ領域改変体
|
|
EP3093294A1
(en)
|
2012-02-24 |
2016-11-16 |
Stemcentrx, Inc. |
Dll3 modulators and methods of use
|
|
TW202500756A
(zh)
|
2012-02-24 |
2025-01-01 |
日商中外製藥股份有限公司 |
經FcγRIIB促進抗原消失之抗原結合分子
|
|
AP2014007875A0
(en)
|
2012-03-05 |
2014-08-31 |
Gilead Calistoga Llc |
Polymorphic forms of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
|
|
AR090281A1
(es)
|
2012-03-08 |
2014-10-29 |
Hanmi Science Co Ltd |
Proceso mejorado para la preparacion de un complejo polipeptidico fisiologicamente activo
|
|
KR101665009B1
(ko)
|
2012-03-09 |
2016-10-11 |
한미사이언스 주식회사 |
비알콜성 지방간 질환의 예방 또는 치료용 약학적 조성물
|
|
US9592289B2
(en)
|
2012-03-26 |
2017-03-14 |
Sanofi |
Stable IgG4 based binding agent formulations
|
|
US10064951B2
(en)
|
2012-03-30 |
2018-09-04 |
Hanmi Science Co., Ltd. |
Liquid formulation of highly concentrated long-acting human growth hormone conjugate
|
|
WO2013169693A1
(en)
|
2012-05-09 |
2013-11-14 |
Bristol-Myers Squibb Company |
Methods of treating cancer using an il-21 polypeptide and an anti-pd-1 antibody
|
|
WO2013166594A1
(en)
|
2012-05-10 |
2013-11-14 |
Zymeworks Inc. |
Heteromultimer constructs of immunoglobulin heavy chains with mutations in the fc domain
|
|
GB201208370D0
(en)
*
|
2012-05-14 |
2012-06-27 |
Ucb Pharma Sa |
Antibodies
|
|
HK1207388A1
(en)
|
2012-05-15 |
2016-01-29 |
Seattle Genetics, Inc. |
Self-stabilizing linker conjugates
|
|
WO2013177470A1
(en)
*
|
2012-05-23 |
2013-11-28 |
Genentech, Inc. |
Selection method for therapeutic agents
|
|
EP3892638A1
(en)
|
2012-05-30 |
2021-10-13 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule for eliminating aggregated antigens
|
|
SG10202006507XA
(en)
|
2012-05-30 |
2020-08-28 |
Chugai Pharmaceutical Co Ltd |
Target-tissue-specific antigen-binding molecule
|
|
US9499634B2
(en)
|
2012-06-25 |
2016-11-22 |
Zymeworks Inc. |
Process and methods for efficient manufacturing of highly pure asymmetric antibodies in mammalian cells
|
|
WO2014004549A2
(en)
|
2012-06-27 |
2014-01-03 |
Amgen Inc. |
Anti-mesothelin binding proteins
|
|
EP2872534B1
(en)
|
2012-07-13 |
2018-08-08 |
Roche Glycart AG |
Bispecific anti-vegf/anti-ang-2 antibodies and their use in the treatment of ocular vascular diseases
|
|
MX366178B
(es)
|
2012-07-19 |
2019-07-01 |
Amgen Inc |
Proteinas de btnl3, acidos nucleicos, y anticuerpos y los usos de los mismos.
|
|
AR092862A1
(es)
|
2012-07-25 |
2015-05-06 |
Hanmi Pharm Ind Co Ltd |
Formulacion liquida de insulina de accion prolongada y un peptido insulinotropico y metodo de preparacion
|
|
RU2681730C2
(ru)
|
2012-07-25 |
2019-03-12 |
Селлдекс Терапьютикс Инк. |
Антитела против kit и их применения
|
|
KR101968344B1
(ko)
|
2012-07-25 |
2019-04-12 |
한미약품 주식회사 |
옥신토모듈린 유도체를 포함하는 고지혈증 치료용 조성물
|
|
AR091902A1
(es)
|
2012-07-25 |
2015-03-11 |
Hanmi Pharm Ind Co Ltd |
Formulacion liquida de un conjugado de insulina de accion prolongada
|
|
TWI855488B
(zh)
|
2012-08-24 |
2024-09-11 |
日商中外製藥股份有限公司 |
FcγRIIb特異性Fc區域變異體
|
|
CA2887129A1
(en)
|
2012-10-09 |
2014-04-17 |
Igenica, Inc. |
Anti-c16orf54 antibodies and methods of use thereof
|
|
CA2890569C
(en)
|
2012-11-05 |
2019-03-05 |
Pfizer Inc. |
Spliceostatin analogs
|
|
NZ739063A
(en)
|
2012-11-06 |
2019-11-29 |
Hanmi Pharm Ind Co Ltd |
Liquid formulation of protein conjugate comprising the oxyntomodulin and an immunoglobulin fragment
|
|
KR101993393B1
(ko)
|
2012-11-06 |
2019-10-01 |
한미약품 주식회사 |
옥신토모듈린 유도체를 포함하는 당뇨병 또는 비만성 당뇨병 치료용 조성물
|
|
KR20150082548A
(ko)
|
2012-11-07 |
2015-07-15 |
화이자 인코포레이티드 |
항-notch3 항체 및 항체-약물 접합체
|
|
UY35144A
(es)
|
2012-11-20 |
2014-06-30 |
Novartis Ag |
Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca
|
|
US9914785B2
(en)
|
2012-11-28 |
2018-03-13 |
Zymeworks Inc. |
Engineered immunoglobulin heavy chain-light chain pairs and uses thereof
|
|
WO2014084859A1
(en)
|
2012-11-30 |
2014-06-05 |
Novartis Ag |
Molecules and methods for modulating tmem16a activities
|
|
US9353150B2
(en)
|
2012-12-04 |
2016-05-31 |
Massachusetts Institute Of Technology |
Substituted pyrazino[1′,2′:1 ,5]pyrrolo[2,3-b]-indole-1,4-diones for cancer treatment
|
|
HUE053669T2
(hu)
|
2012-12-05 |
2021-07-28 |
Novartis Ag |
Készítmények és eljárások EPO-t célzó antitestekre
|
|
CN105051064A
(zh)
|
2013-01-24 |
2015-11-11 |
葛兰素史克知识产权开发有限公司 |
抗TNF-α抗原结合蛋白
|
|
KR102073748B1
(ko)
|
2013-01-31 |
2020-02-05 |
한미약품 주식회사 |
재조합 효모 형질전환체 및 이를 이용하여 면역글로불린 단편을 생산하는 방법
|
|
US10183967B2
(en)
|
2013-02-12 |
2019-01-22 |
Bristol-Myers Squibb Company |
Tangential flow filtration based protein refolding methods
|
|
EP3299378B1
(en)
|
2013-02-12 |
2019-07-31 |
Bristol-Myers Squibb Company |
High ph protein refolding methods
|
|
WO2014129895A1
(en)
|
2013-02-19 |
2014-08-28 |
Stichting Vu-Vumc |
Means and method for increasing the sensitivity of cancers for radiotherapy
|
|
RU2019109456A
(ru)
|
2013-02-22 |
2019-04-10 |
ЭББВИ СТЕМСЕНТРКС ЭлЭлСи |
Новые конъюгаты антител и их применения
|
|
SG11201505615PA
(en)
|
2013-02-26 |
2015-09-29 |
Hanmi Pharm Ind Co Ltd |
Site-specific insulin conjugate
|
|
PE20151409A1
(es)
|
2013-02-26 |
2015-10-07 |
Hanmi Pharm Ind Co Ltd |
Analogo de insulina novedoso y su uso
|
|
US9487587B2
(en)
|
2013-03-05 |
2016-11-08 |
Macrogenics, Inc. |
Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof
|
|
PT2966083T
(pt)
|
2013-03-05 |
2019-09-17 |
Hanmi Pharm Ind Co Ltd |
Método de preparação melhorado para produção de alto rendimento de conjugado de polipéptido fisiologicamente ativo
|
|
EP2964669B1
(en)
|
2013-03-06 |
2018-09-12 |
Protalix Ltd. |
Use of plant cells expressing a tnfalpha polypeptide inhibitor in therapy
|
|
US20160017021A1
(en)
|
2013-03-06 |
2016-01-21 |
Protalix Ltd. |
TNF alpha INHIBITOR POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME, CELLS EXPRESSING SAME AND METHODS OF PRODUCING SAME
|
|
US10344060B2
(en)
|
2013-03-12 |
2019-07-09 |
Amgen Inc. |
Potent and selective inhibitors of Nav1.7
|
|
EP2968520B1
(en)
|
2013-03-14 |
2021-05-12 |
MacroGenics, Inc. |
Bispecific molecules that are immunoreactive with immune effector cells that express an activating receptor
|
|
CN105246916A
(zh)
|
2013-03-14 |
2016-01-13 |
诺华股份有限公司 |
针对notch 3的抗体
|
|
US20160184458A1
(en)
|
2013-03-14 |
2016-06-30 |
Shire Human Genetic Therapies, Inc. |
Mrna therapeutic compositions and use to treat diseases and disorders
|
|
CN105377892A
(zh)
|
2013-03-15 |
2016-03-02 |
艾伯维生物技术有限公司 |
抗cd25抗体及其用途
|
|
CA2907249A1
(en)
|
2013-03-15 |
2014-09-18 |
Dana-Farber Cancer Institute, Inc. |
Therapeutic peptides
|
|
BR112015023086A2
(pt)
|
2013-03-15 |
2017-11-21 |
Abbvie Biotechnology Ltd |
anticorpo anti-cd25 monoclonal ou um fragmento ligante anti-cd25 de um anticorpo monoclonal, conjugado de anticorpo-droga, composição farmacêutica, ácido nucleico, vetor, célula hospedeira, métodos para produção de um anticorpo anti-cd25 ou fragmento ligante anti cd25, para prevenção de rejeição de órgãos transplantados e para tratamento de uma doença.
|
|
AU2014228489B2
(en)
|
2013-03-15 |
2018-11-15 |
Zymeworks Bc Inc. |
Cytotoxic and anti-mitotic compounds, and methods of using the same
|
|
CA2904528C
(en)
|
2013-03-15 |
2021-01-19 |
Abbvie Biotherapeutics Inc. |
Fc variants
|
|
US20160051673A1
(en)
|
2013-03-29 |
2016-02-25 |
Alexion Pharmaceuticals, Inc. |
Compositions and methods for increasing the serum half-life of a therapeutic agent targeting complement c5
|
|
AU2014250434B2
(en)
|
2013-04-02 |
2019-08-08 |
Chugai Seiyaku Kabushiki Kaisha |
Fc region variant
|
|
US20160068613A1
(en)
|
2013-04-29 |
2016-03-10 |
Hoffmann-La Roche Inc. |
Fc-receptor binding modified asymmetric antibodies and methods of use
|
|
KR101895634B1
(ko)
|
2013-05-31 |
2018-09-05 |
한미약품 주식회사 |
변이된 힌지 영역을 포함하는 IgG4 Fc 단편
|
|
JP6824735B2
(ja)
|
2013-06-06 |
2021-02-03 |
ピエール、ファーブル、メディカマン |
抗Ｃ１０ｏｒｆ５４抗体およびその使用方法
|
|
EP3008091A1
(en)
|
2013-06-13 |
2016-04-20 |
Fast Forward Pharmaceuticals B.V. |
Cd40 signalling inhibitor and a further compound, wherein the further compound is a bile acid, a bile acid derivative, an tgr5-receptor agonist, an fxr agonist or a combination thereof, for the treatment of chronic inflammation, and the prevention of gastrointestinal cancer or fibrosis.
|
|
AR096601A1
(es)
|
2013-06-21 |
2016-01-20 |
Novartis Ag |
Anticuerpos del receptor 1 de ldl oxidado similar a lectina y métodos de uso
|
|
US9562101B2
(en)
|
2013-06-21 |
2017-02-07 |
Novartis Ag |
Lectin-like oxidized LDL receptor 1 antibodies and methods of use
|
|
AR096890A1
(es)
|
2013-07-12 |
2016-02-03 |
Hanmi Pharm Ind Co Ltd |
Conjugando fc de inmunoglobulina, que mantiene la afinidad de unión del fragmento fc de la inmunoglobulina a fcrn
|
|
AR096891A1
(es)
|
2013-07-12 |
2016-02-03 |
Hanmi Pharm Ind Co Ltd |
Conjugado de monómero polipéptido biológicamente activo y conjugado de fragmento fc de inmunoglobulina, que muestra aclaramiento mediado por receptor reducido, y el método para la preparación del mismo
|
|
JP6687520B2
(ja)
|
2013-07-18 |
2020-04-22 |
トーラス バイオサイエンシズ リミテッド ライアビリティ カンパニー |
極めて長い相補性決定領域を有するヒト化抗体
|
|
EP3022224A2
(en)
|
2013-07-18 |
2016-05-25 |
Fabrus, Inc. |
Antibodies with ultralong complementarity determining regions
|
|
PE20160991A1
(es)
|
2013-07-25 |
2016-10-15 |
Novartis Ag |
Bioconjugados de polipeptidos de apelina sintetica
|
|
TW201536814A
(zh)
|
2013-07-25 |
2015-10-01 |
Novartis Ag |
用於治療心臟衰竭之合成環狀多肽
|
|
AU2014296288B2
(en)
|
2013-07-31 |
2020-02-13 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for modulating thermogenesis using PTH-related and EGF-related molecules
|
|
UA116479C2
(uk)
|
2013-08-09 |
2018-03-26 |
Макродженікс, Інк. |
БІСПЕЦИФІЧНЕ МОНОВАЛЕНТНЕ Fc-ДІАТІЛО, ЯКЕ ОДНОЧАСНО ЗВ'ЯЗУЄ CD32B I CD79b, ТА ЙОГО ЗАСТОСУВАННЯ
|
|
US11384149B2
(en)
|
2013-08-09 |
2022-07-12 |
Macrogenics, Inc. |
Bi-specific monovalent Fc diabodies that are capable of binding CD32B and CD79b and uses thereof
|
|
EP2840091A1
(en)
|
2013-08-23 |
2015-02-25 |
MacroGenics, Inc. |
Bi-specific diabodies that are capable of binding gpA33 and CD3 and uses thereof
|
|
EP2839842A1
(en)
|
2013-08-23 |
2015-02-25 |
MacroGenics, Inc. |
Bi-specific monovalent diabodies that are capable of binding CD123 and CD3 and uses thereof
|
|
US9475874B2
(en)
|
2013-08-26 |
2016-10-25 |
MabVax Therapeutics, Inc. |
Nucleic acids encoding human antibodies to sialyl-lewisa
|
|
JP2016538318A
(ja)
|
2013-08-28 |
2016-12-08 |
ステムセントリックス， インコーポレイテッド |
新規ｓｅｚ６モジュレーターおよび使用方法
|
|
WO2015031698A1
(en)
|
2013-08-28 |
2015-03-05 |
Stem Centrx, Inc. |
Site-specific antibody conjugation methods and compositions
|
|
WO2015035044A2
(en)
|
2013-09-04 |
2015-03-12 |
Abbvie Biotherapeutics Inc. |
Fc VARIANTS WITH IMPROVED ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY
|
|
CN114288254A
(zh)
|
2013-09-27 |
2022-04-08 |
韩美药品株式会社 |
长效人生长激素缀合物的制剂
|
|
CA3187392A1
(en)
|
2013-10-15 |
2015-04-23 |
Seagen Inc. |
Pegylated drug-linkers for improved ligand-drug conjugate pharmacokinetics
|
|
US20160235810A1
(en)
|
2013-10-18 |
2016-08-18 |
Novartis Ag |
Methods of treating diabetes and related disorders
|
|
PE20160870A1
(es)
|
2013-11-06 |
2016-09-09 |
Abbvie Stemcentrx Llc |
Anticuerpos anti-claudina novedosos y metodos de uso
|
|
PT3074424T
(pt)
|
2013-11-27 |
2025-05-29 |
Zymeworks Bc Inc |
Construções de ligação a antigénio biespecíficas direcionadas a her2
|
|
BR112016012358A2
(pt)
|
2013-12-06 |
2017-09-26 |
Dana Farber Cancer Inst Inc |
peptídios terapêuticos
|
|
EP3082878B1
(en)
|
2013-12-19 |
2022-10-05 |
Seagen Inc. |
Methylene carbamate linkers for use with targeted-drug conjugates
|
|
PT3083630T
(pt)
|
2013-12-20 |
2019-11-15 |
Gilead Calistoga Llc |
Procedimentos para inibidores da fosfatidilinositol 3-quinase
|
|
EP3083623A1
(en)
|
2013-12-20 |
2016-10-26 |
Gilead Calistoga LLC |
Polymorphic forms of a hydrochloride salt of (s) -2-(9h-purin-6-ylamino) propyl) -5-fluoro-3-phenylquinazolin-4 (3h) -one
|
|
PL3087095T3
(pl)
|
2013-12-24 |
2020-03-31 |
Argenx Bvba |
Antagoniści fcrn i sposoby stosowania
|
|
DK3086815T3
(da)
|
2013-12-27 |
2022-05-23 |
Zymeworks Inc |
Sulfonamidholdige forbindelsessystemer til lægemiddelkonjugater
|
|
CA2932364A1
(en)
|
2014-01-15 |
2015-07-23 |
F. Hoffmann-La Roche Ag |
Fc-region variants with improved protein a-binding
|
|
WO2015107026A1
(en)
*
|
2014-01-15 |
2015-07-23 |
F. Hoffmann-La Roche Ag |
Fc-region variants with modified fcrn- and maintained protein a-binding properties
|
|
US10253082B2
(en)
|
2014-01-20 |
2019-04-09 |
Hanmi Pharm. Co., Ltd |
Long-acting insulin and use thereof
|
|
AU2015209131B2
(en)
|
2014-01-24 |
2020-06-25 |
Ngm Biopharmaceuticals, Inc. |
Binding proteins and methods of use thereof
|
|
KR101871088B1
(ko)
|
2014-01-27 |
2018-06-25 |
화이자 인코포레이티드 |
이관능성 세포독성제
|
|
JP6716461B2
(ja)
|
2014-02-17 |
2020-07-01 |
シアトル ジェネティックス， インコーポレイテッド |
親水性抗体−薬物コンジュゲート
|
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
|
NZ631007A
(en)
|
2014-03-07 |
2015-10-30 |
Alexion Pharma Inc |
Anti-c5 antibodies having improved pharmacokinetics
|
|
WO2015139020A2
(en)
|
2014-03-14 |
2015-09-17 |
Dana-Farber Cancer Institute, Inc. |
Vaccine compositions and methods for restoring nkg2d pathway function against cancers
|
|
MY192248A
(en)
|
2014-03-31 |
2022-08-10 |
Hanmi Pharm Ind Co Ltd |
Method for improving solubility of protein and peptide by using immunoglobulin fc fragment linkage
|
|
AU2015240599B2
(en)
|
2014-04-04 |
2020-11-19 |
Bionomics, Inc. |
Humanized antibodies that bind LGR5
|
|
WO2015175375A1
(en)
|
2014-05-13 |
2015-11-19 |
Short Jay M |
Conditionally active biological proteins
|
|
CN106413750B
(zh)
|
2014-05-16 |
2022-04-29 |
免疫医疗有限责任公司 |
具有增强的治疗和诊断特性的带有改变的新生儿Fc受体结合的分子
|
|
AU2015266958A1
(en)
|
2014-05-28 |
2016-12-08 |
Agenus Inc. |
Anti-GITR antibodies and methods of use thereof
|
|
AR100639A1
(es)
|
2014-05-29 |
2016-10-19 |
Hanmi Pharm Ind Co Ltd |
Composición para tratar diabetes que comprende conjugados de análogos de insulina de acción prolongada y conjugados de péptidos insulinotrópicos de acción prolongada
|
|
TWI684458B
(zh)
|
2014-05-30 |
2020-02-11 |
南韓商韓美藥品股份有限公司 |
包含胰島素及ｇｌｐ-１/昇糖素雙重促效劑之治療糖尿病之組成物
|
|
CA2950602C
(en)
|
2014-06-04 |
2021-07-20 |
MabVax Therapeutics, Inc. |
Human monoclonal antibodies to ganglioside gd2
|
|
KR20150140177A
(ko)
|
2014-06-05 |
2015-12-15 |
한미약품 주식회사 |
단백질 및 펩타이드의 면역원성을 감소시키는 방법
|
|
JP6449338B2
(ja)
|
2014-06-06 |
2019-01-09 |
ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ |
グルココルチコイド誘導腫瘍壊死因子受容体（ｇｉｔｒ）に対する抗体およびその使用
|
|
AU2015274574B2
(en)
|
2014-06-10 |
2019-10-10 |
Amgen Inc. |
Apelin polypeptides
|
|
JP6455995B2
(ja)
|
2014-06-13 |
2019-01-23 |
ギリアード サイエンシーズ， インコーポレイテッド |
ホスファチジルイノシトール３−キナーゼ阻害剤
|
|
CN112851790A
(zh)
|
2014-06-23 |
2021-05-28 |
诺华股份有限公司 |
位点特异性蛋白质修饰
|
|
KR102762243B1
(ko)
|
2014-06-30 |
2025-02-05 |
알토 바이오사이언스 엘엘씨 |
Il-15-베이즈드 분자 및 이의 사용 방법
|
|
PT3177642T
(pt)
|
2014-08-07 |
2022-02-14 |
Novartis Ag |
Anticorpos semelhantes a angiopoietina 4 e métodos de uso
|
|
WO2016020882A2
(en)
|
2014-08-07 |
2016-02-11 |
Novartis Ag |
Angiopoetin-like 4 (angptl4) antibodies and methods of use
|
|
MY192824A
(en)
|
2014-09-03 |
2022-09-12 |
Boehringer Ingelheim Int |
Compound targeting il-23a and tnf-alpha and uses thereof
|
|
KR20170044115A
(ko)
|
2014-09-03 |
2017-04-24 |
바이오아트라, 엘엘씨 |
동일한 진핵생물 세포 생산 숙주 내 조건부 활성 생체 단백질의 발견 및 제조
|
|
TW201617368A
(zh)
|
2014-09-05 |
2016-05-16 |
史坦森特瑞斯公司 |
新穎抗ｍｆｉ２抗體及使用方法
|
|
CA2960756C
(en)
|
2014-09-15 |
2023-08-01 |
Amgen Inc. |
Bi-specific anti-cgrp receptor/pac1 receptor antigen binding proteins and uses thereof
|
|
TWI772252B
(zh)
|
2014-09-16 |
2022-08-01 |
南韓商韓美藥品股份有限公司 |
長效glp-1/高血糖素受體雙促效劑治療非酒精性脂肝疾病之用途
|
|
RU2723651C2
(ru)
|
2014-09-17 |
2020-06-17 |
Займворкс Инк. |
Цитотоксические и антимитотические соединения и способы их применения
|
|
US10717778B2
(en)
|
2014-09-29 |
2020-07-21 |
Duke University |
Bispecific molecules comprising an HIV-1 envelope targeting arm
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
HUE050596T2
(hu)
|
2014-11-21 |
2020-12-28 |
Bristol Myers Squibb Co |
Antitestek CD73 ellen és azok felhasználásai
|
|
LT3221346T
(lt)
|
2014-11-21 |
2020-11-10 |
Bristol-Myers Squibb Company |
Antikūnai, apimantys modifikuotas sunkiosios grandinės pastoviąsias sritis
|
|
GB201421901D0
(en)
|
2014-12-09 |
2015-01-21 |
Cambridge Entpr Ltd |
A method of rational antibody design
|
|
CA2970352A1
(en)
|
2014-12-11 |
2016-06-16 |
Pierre Fabre Medicament |
Anti-c10orf54 antibodies and uses thereof
|
|
WO2016094834A2
(en)
|
2014-12-12 |
2016-06-16 |
Alexion Pharmaceuticals, Inc. |
A method for treating a complement mediated disorder caused by an infectious agent in a patient
|
|
UY36449A
(es)
|
2014-12-19 |
2016-07-29 |
Novartis Ag |
Composiciones y métodos para anticuerpos dirigidos a bmp6
|
|
TWI656133B
(zh)
|
2014-12-19 |
2019-04-11 |
日商中外製藥股份有限公司 |
抗肌抑素之抗體、含變異Ｆｃ區域之多胜肽及使用方法
|
|
US10221248B2
(en)
|
2014-12-22 |
2019-03-05 |
The Rockefeller University |
Anti-MERTK agonistic antibodies and uses thereof
|
|
AR103268A1
(es)
|
2014-12-23 |
2017-04-26 |
Bristol Myers Squibb Co |
Anticuerpos contra tigit
|
|
TN2017000271A1
(en)
|
2014-12-30 |
2018-10-19 |
Hanmi Pharm Ind Co Ltd |
Glucagon derivative having improved stability
|
|
KR102418477B1
(ko)
|
2014-12-30 |
2022-07-08 |
한미약품 주식회사 |
글루카곤 유도체
|
|
CA2973978A1
(en)
|
2015-01-14 |
2016-07-21 |
The Brigham And Women's Hospital, Inc. |
Treatment of cancer with anti-lap monoclonal antibodies
|
|
WO2016123454A1
(en)
|
2015-01-29 |
2016-08-04 |
Board Of Trustees Of Miching State University |
Cryptic polypeptides and uses thereof
|
|
WO2016125495A1
(en)
|
2015-02-05 |
2016-08-11 |
Chugai Seiyaku Kabushiki Kaisha |
Antibodies comprising an ion concentration dependent antigen-binding domain, fc region variants, il-8-binding antibodies, and uses therof
|
|
CN107810202A
(zh)
|
2015-02-17 |
2018-03-16 |
韩美药品株式会社 |
长效胰岛素或胰岛素类似物复合物
|
|
AU2016222830B2
(en)
|
2015-02-24 |
2021-02-25 |
Bioatla Llc |
Conditionally active biological proteins
|
|
WO2016141111A1
(en)
|
2015-03-03 |
2016-09-09 |
Xoma (Us) Llc |
Treatment of post-prandial hyperinsulinemia and hypoglycemia after bariatric surgery
|
|
HRP20230046T1
(hr)
|
2015-03-03 |
2023-03-03 |
Kymab Limited |
Protutijela, upotreba i postupci
|
|
BR112017018706B1
(pt)
|
2015-03-20 |
2023-01-24 |
Pfizer Inc |
Agentes citotóxicos bifuncionais contendo o farmacoforo cti, composição farmacêutica e uso dos mesmos
|
|
UY36687A
(es)
|
2015-05-29 |
2016-11-30 |
Bristol Myers Squibb Company Una Corporación Del Estado De Delaware |
Anticuerpos contra ox40 y sus usos
|
|
CN107614526A
(zh)
|
2015-06-05 |
2018-01-19 |
诺华股份有限公司 |
靶向骨形成蛋白9(bmp9)的抗体及其方法
|
|
JOP20200312A1
(ar)
|
2015-06-26 |
2017-06-16 |
Novartis Ag |
الأجسام المضادة للعامل xi وطرق الاستخدام
|
|
KR20180021833A
(ko)
|
2015-06-29 |
2018-03-05 |
더 락커펠러 유니버시티 |
증진된 효능제 활성을 갖는 cd40에 대한 항체
|
|
TN2017000555A1
(en)
|
2015-06-30 |
2019-04-12 |
Hanmi Pharm Ind Co Ltd |
Glucagon derivative and a composition comprising a long acting conjugate of the same
|
|
RU2752530C2
(ru)
|
2015-08-03 |
2021-07-29 |
Новартис Аг |
Способы лечения расстройств, связанных с fgf21
|
|
EP3763378A1
(en)
|
2015-08-06 |
2021-01-13 |
President and Fellows of Harvard College |
Improved microbe-binding molecules and uses thereof
|
|
UY36870A
(es)
|
2015-08-28 |
2017-03-31 |
Hanmi Pharm Ind Co Ltd |
Análogos de insulina novedosos
|
|
CN114605548A
(zh)
|
2015-09-01 |
2022-06-10 |
艾吉纳斯公司 |
抗-pd-1抗体及其使用方法
|
|
PT3347377T
(pt)
|
2015-09-09 |
2021-04-30 |
Novartis Ag |
Anticorpos que se ligam à linfopoietina do estroma tímico (tslp) e métodos de utilização dos anticorpos
|
|
AU2016320748B2
(en)
|
2015-09-09 |
2019-05-02 |
Novartis Ag |
Thymic stromal lymphopoietin (TSLP)-binding antibodies and methods of using the antibodies
|
|
AU2016323440B2
(en)
|
2015-09-15 |
2023-07-13 |
Amgen Inc. |
Tetravalent bispecific and tetraspecific antigen binding proteins and uses thereof
|
|
EP3341025A4
(en)
|
2015-09-24 |
2019-05-01 |
Hanmi Pharm. Co., Ltd. |
PROTEIN COMPLEX BY USING A SPECIFIC ROLE OF AN IMMUNOMOBILIN FRAGMENT FOR LINKING
|
|
US10358497B2
(en)
|
2015-09-29 |
2019-07-23 |
Amgen Inc. |
Methods of treating cardiovascular disease with an ASGR inhibitor
|
|
HK1251158A1
(zh)
|
2015-09-29 |
2019-01-25 |
细胞基因公司 |
Pd-1结合蛋白及其使用方法
|
|
JP2018529729A
(ja)
|
2015-10-01 |
2018-10-11 |
アムジエン・インコーポレーテツド |
胆汁酸障害の処置
|
|
WO2017079272A2
(en)
|
2015-11-03 |
2017-05-11 |
Ambrx, Inc. |
Anti-cd3-folate conjugates and their uses
|
|
EP3165532B1
(en)
|
2015-11-03 |
2018-12-19 |
Industrial Technology Research Institute |
Auristatin derivatives, linker-drugs and ligand-drug conjugates
|
|
CN108738324B
(zh)
|
2015-11-19 |
2022-06-21 |
百时美施贵宝公司 |
抗糖皮质激素诱导的肿瘤坏死因子受体(gitr)抗体及其用途
|
|
US10188660B2
(en)
|
2015-11-30 |
2019-01-29 |
Abbvie Inc. |
Anti-huLRRC15 antibody drug conjugates and methods for their use
|
|
WO2017095808A1
(en)
|
2015-11-30 |
2017-06-08 |
Abbvie Inc. |
ANTI-huLRRC15 ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE
|
|
SG10201912984WA
(en)
|
2015-12-02 |
2020-03-30 |
Agenus Inc |
Antibodies and methods of use thereof
|
|
US11229708B2
(en)
|
2015-12-04 |
2022-01-25 |
Seagen Inc. |
Conjugates of quaternized tubulysin compounds
|
|
WO2017096262A1
(en)
|
2015-12-04 |
2017-06-08 |
Jomoco, Corp. |
Compositions and methods to mitigate or prevent an immune response to an immunogenic therapeutic molecule in non-human primates
|
|
EP3383891A1
(en)
|
2015-12-04 |
2018-10-10 |
Novartis AG |
Antibody cytokine engrafted compositions and methods of use for immunoregulation
|
|
EP3390447A1
(en)
|
2015-12-15 |
2018-10-24 |
Amgen Inc. |
Pacap antibodies and uses thereof
|
|
CR20180365A
(es)
|
2015-12-16 |
2018-09-28 |
Amgen Inc |
PROTEÍNAS DE UNIÓN AL ANTÍGENO BISPECÍFICO DE ANTI-TL1A/ANTI-TNF-a Y SUS USOS
|
|
UY37030A
(es)
|
2015-12-18 |
2017-07-31 |
Novartis Ag |
Anticuerpos dirigidos a cd32b y métodos de uso de los mismos
|
|
WO2017110981A1
(en)
|
2015-12-25 |
2017-06-29 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-myostatin antibodies and methods of use
|
|
PH12018501409B1
(en)
|
2015-12-31 |
2023-03-10 |
Hanmi Pharmaceutical Co Ltd |
Triple glucagon/glp-1/gip receptor agonist
|
|
BR112018014150A2
(en)
|
2016-01-11 |
2018-12-11 |
Novartis Ag |
immunostimulating humanized monoclonal antibodies to human interleukin-2, and fusion proteins thereof
|
|
EP3851457A1
(en)
|
2016-01-21 |
2021-07-21 |
Novartis AG |
Multispecific molecules targeting cll-1
|
|
AR107483A1
(es)
|
2016-01-29 |
2018-05-02 |
Hanmi Pharm Ind Co Ltd |
Conjugado de enzimas terapéuticas
|
|
US10723727B2
(en)
|
2016-02-01 |
2020-07-28 |
Pfizer Inc. |
Tubulysin analogs and methods for their preparation
|
|
IL261602B2
(en)
|
2016-03-04 |
2024-06-01 |
Univ Rockefeller |
Antibodies to cd40 with enhanced agonist activity
|
|
IL295230A
(en)
|
2016-03-04 |
2022-10-01 |
Bristol Myers Squibb Co |
Combination therapy with anti-cd73 antibodies
|
|
AR107823A1
(es)
|
2016-03-07 |
2018-06-06 |
Hanmi Pharm Ind Co Ltd |
Derivados de polietilenglicol y uso de los mismos
|
|
WO2017161173A1
(en)
|
2016-03-16 |
2017-09-21 |
Merrimack Pharmaceuticals, Inc. |
Engineered trail for cancer therapy
|
|
EP3432925A4
(en)
|
2016-03-22 |
2019-11-06 |
Bionomics Limited |
ADMINISTRATION OF A MONOCLONAL ANTI-LGR5 ANTIBODY
|
|
MA43835A
(fr)
|
2016-03-25 |
2018-11-28 |
Seattle Genetics Inc |
Procédé de préparation de lieurs de médicaments pégylés et leurs intermédiaires
|
|
KR102775461B1
(ko)
|
2016-04-01 |
2025-02-28 |
어비디티 바이오사이언시스 인크. |
핵산-폴리펩타이드 조성물 및 이의 용도
|
|
US10934347B2
(en)
|
2016-04-04 |
2021-03-02 |
Genzyme Corporation |
Anti-complement factor BB antibodies and uses thereof
|
|
TWI781098B
(zh)
|
2016-04-15 |
2022-10-21 |
美商宏觀基因股份有限公司 |
新穎的ｂ７-ｈ３-結合分子、其抗體藥物綴合物及其使用方法
|
|
WO2017184942A1
(en)
|
2016-04-21 |
2017-10-26 |
Abbvie Stemcentrx Llc |
Novel anti-bmpr1b antibodies and methods of use
|
|
CN109071647B
(zh)
|
2016-04-27 |
2022-11-22 |
诺华股份有限公司 |
抗生长分化因子15的抗体及其用途
|
|
WO2017197045A1
(en)
|
2016-05-11 |
2017-11-16 |
Movassaghi Mohammad |
Convergent and enantioselective total synthesis of communesin analogs
|
|
TWI781934B
(zh)
|
2016-05-27 |
2022-11-01 |
美商艾吉納斯公司 |
抗-tim-3抗體及其使用方法
|
|
KR102463844B1
(ko)
*
|
2016-05-27 |
2022-11-08 |
알토 바이오사이언스 코포레이션 |
Cd3 결합 도메인을 가지는 다량체 il-15 기반 분자의 구성 및 특성규명
|
|
EP3463461A4
(en)
|
2016-05-27 |
2020-05-20 |
Alexion Pharmaceuticals, Inc. |
Methods for treatment of refractory generalized myasthenia gravis
|
|
CA3026880A1
(en)
|
2016-06-08 |
2017-12-14 |
Xencor, Inc. |
Methods and compositions for inhibiting cd32b expressing cells in igg4-related diseases
|
|
AU2017283787B2
(en)
|
2016-06-15 |
2020-09-17 |
Novartis Ag |
Methods for treating disease using inhibitors of bone morphogenetic protein 6 (BMP6)
|
|
US10815306B2
(en)
|
2016-06-16 |
2020-10-27 |
The Board Of Trustees Of The Leland Stanford Junior University |
Humanized and chimeric monoclonal antibodies to CD81
|
|
WO2017223111A1
(en)
|
2016-06-21 |
2017-12-28 |
Teneobio, Inc. |
Cd3 binding antibodies
|
|
JP7208020B2
(ja)
|
2016-06-29 |
2023-01-18 |
ハンミ ファーマシューティカル カンパニー リミテッド |
グルカゴン誘導体、その結合体、及びそれを含む組成物、並びにその治療的用途
|
|
KR20190039937A
(ko)
|
2016-07-08 |
2019-04-16 |
스태튼 바이오테크놀로지 비.브이. |
항-ApoC3 항체 및 이의 사용 방법
|
|
JP7027401B2
(ja)
|
2016-07-14 |
2022-03-01 |
ブリストル－マイヤーズ スクイブ カンパニー |
Ｔｉｍ３に対する抗体およびその使用
|
|
KR20250036943A
(ko)
|
2016-08-02 |
2025-03-14 |
비스테라, 인크. |
조작된 폴리펩티드 및 그의 용도
|
|
JP2018058822A
(ja)
|
2016-08-03 |
2018-04-12 |
ファイザー・インク |
ヘテロアリールスルホンをベースとするコンジュゲーションハンドル、これらの調製のための方法、および抗体薬物コンジュゲートの合成におけるこれらの使用
|
|
CN109689099B
(zh)
|
2016-08-05 |
2023-02-28 |
中外制药株式会社 |
用于预防或治疗il-8相关疾病的组合物
|
|
KR20240010534A
(ko)
|
2016-08-09 |
2024-01-23 |
씨젠 인크. |
개선된 물리화학적 특성을 갖는 자기 안정화 링커를 구비한 약물 접합체
|
|
WO2018044970A1
(en)
|
2016-08-31 |
2018-03-08 |
University Of Rochester |
Human monoclonal antibodies to human endogenous retrovirus k envelope (herv-k) and uses thereof
|
|
HRP20240767T1
(hr)
|
2016-09-14 |
2024-09-13 |
Teneoone, Inc. |
Cd3 vezujuća antitijela
|
|
AU2017329024A1
(en)
|
2016-09-19 |
2019-03-21 |
Celgene Corporation |
Methods of treating immune disorders using pd-1 binding proteins
|
|
WO2018053401A1
(en)
|
2016-09-19 |
2018-03-22 |
Celgene Corporation |
Methods of treating vitiligo using pd-1 binding proteins
|
|
US11396534B2
(en)
|
2016-09-23 |
2022-07-26 |
Hanmi Pharm. Co., Ltd. |
Insulin analogs with reduced affinity to insulin receptor and use thereof
|
|
TW202436356A
(zh)
|
2016-10-11 |
2024-09-16 |
美商艾吉納斯公司 |
抗ｌａｇ－３抗體及其使用方法
|
|
EA201990890A1
(ru)
|
2016-10-18 |
2019-10-31 |
|
Целевая доставка ингибиторов реутилизационного пути никотинамидадениндинуклеотида
|
|
JP7096240B2
(ja)
|
2016-10-19 |
2022-07-05 |
アレクシオン ファーマシューティカルズ， インコーポレイテッド |
試料中の非結合ｃ５の定量化方法
|
|
EP3529263B1
(en)
|
2016-10-21 |
2025-08-06 |
Altor BioScience Corporation |
Multimeric il-15-based molecules
|
|
US11779604B2
(en)
|
2016-11-03 |
2023-10-10 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses and methods
|
|
EP3538152A4
(en)
|
2016-11-09 |
2020-09-30 |
Agenus Inc. |
ANTI-OX40 ANTIBODIES, ANTI-GITR ANTIBODIES, AND PROCESSES FOR USE
|
|
MX2019005552A
(es)
|
2016-11-14 |
2019-08-12 |
Amgen Inc |
Proteinas de union a antigenos biespecificas o biparatopicas y usos de las mismas.
|
|
JP7227146B2
(ja)
|
2016-11-23 |
2023-02-21 |
バイオベラティブ セラピューティクス インコーポレイテッド |
凝固第ｉｘ因子および凝固第ｘ因子に結合する二重特異性抗体
|
|
US20200078470A1
(en)
|
2016-12-05 |
2020-03-12 |
Hanmi Pharm. Co., Ltd. |
Conjugate with attenuated immune response
|
|
WO2018104893A1
(en)
|
2016-12-06 |
2018-06-14 |
Glaxosmithkline Intellectual Property Development Limited |
Alpha4-beta7 antibodies with incrased fcrn binding and/or half-life
|
|
US11013802B2
(en)
|
2016-12-07 |
2021-05-25 |
Agenus Inc. |
Anti-CTLA-4 antibodies and methods of use thereof
|
|
CN118634323A
(zh)
|
2016-12-07 |
2024-09-13 |
艾吉纳斯公司 |
抗体和其使用方法
|
|
WO2018117613A1
(ko)
|
2016-12-19 |
2018-06-28 |
한미약품 주식회사 |
뇌 표적 지속성 단백질 결합체
|
|
BR112019012354A2
(pt)
|
2016-12-21 |
2019-11-26 |
Teneobio, Inc. |
anticorpos apenas de cadeia pesada anti-bcma
|
|
US11168147B2
(en)
|
2016-12-23 |
2021-11-09 |
Novartis Ag |
Factor XI antibodies and methods of use
|
|
KR102702288B1
(ko)
|
2016-12-23 |
2024-09-05 |
노파르티스 아게 |
항-인자 XI/XIa 항체를 사용한 치료 방법
|
|
SG10202107429WA
(en)
|
2017-01-06 |
2021-08-30 |
Avidity Biosciences Inc |
Nucleic acid-polypeptide compositions and methods of inducing exon skipping
|
|
US20180244785A1
(en)
|
2017-01-09 |
2018-08-30 |
Merrimack Pharmaceuticals, Inc. |
Anti-fgfr antibodies and methods of use
|
|
BR112019015069A2
(pt)
|
2017-01-24 |
2020-03-03 |
Pfizer Inc. |
Derivados de caliqueamicina e conjugados de anticorpo-fármaco dos mesmos
|
|
WO2018143729A1
(ko)
|
2017-02-03 |
2018-08-09 |
한미약품 주식회사 |
지속성이 증가된 생리활성 물질의 결합체 및 이의 용도
|
|
WO2018147641A1
(ko)
|
2017-02-07 |
2018-08-16 |
한미약품 주식회사 |
비펩티드성 중합체 링커 화합물, 그 링커 화합물을 포함하는 결합체, 및 이들의 제조방법
|
|
WO2018146594A1
(en)
|
2017-02-08 |
2018-08-16 |
Novartis Ag |
Fgf21 mimetic antibodies and uses thereof
|
|
BR112019016374A2
(pt)
|
2017-02-17 |
2020-04-07 |
Bristol-Myers Squibb Company |
anticorpos para alfa-sinucleína e usos dos mesmos
|
|
KR20250150164A
(ko)
|
2017-03-06 |
2025-10-17 |
알토 바이오사이언스 엘엘씨 |
Il-12 및 il-18로의 il-15-기반 융합
|
|
KR101941975B1
(ko)
|
2017-03-17 |
2019-01-25 |
고려대학교 산학협력단 |
Atpif1을 함유하는 당뇨 치료용 약학조성물
|
|
WO2018174668A2
(ko)
|
2017-03-23 |
2018-09-27 |
한미약품 주식회사 |
인슐린 수용체와의 결합력이 감소된 인슐린 아날로그의 결합체 및 이의 용도
|
|
KR102648564B1
(ko)
|
2017-03-24 |
2024-03-19 |
씨젠 인크. |
글루쿠로니드 약물-링커의 제조 공정 및 그 중간물
|
|
US20190048055A1
(en)
|
2017-03-31 |
2019-02-14 |
Altor Bioscience Corporation |
Alt-803 in combination with anti-cd38 antibody for cancer therapies
|
|
JP2020513019A
(ja)
|
2017-04-05 |
2020-04-30 |
ノヴォ ノルディスク アー／エス |
オリゴマー伸長インスリン−Ｆｃコンジュゲート
|
|
US11634495B2
(en)
|
2017-04-07 |
2023-04-25 |
Miltenyi Biotec B.V. & Co. KG |
Methods of activating CD32b/c comprising administering an antibody that binds BDCA-2 (CD303)
|
|
TWI788340B
(zh)
|
2017-04-07 |
2023-01-01 |
美商必治妥美雅史谷比公司 |
抗icos促效劑抗體及其用途
|
|
KR102629972B1
(ko)
|
2017-04-13 |
2024-01-29 |
아게누스 인코포레이티드 |
항-cd137 항체 및 이의 사용 방법
|
|
CA3059133A1
(en)
|
2017-04-21 |
2018-10-25 |
Staten Biotechnology B.V. |
Anti-apoc3 antibodies and methods of use thereof
|
|
JOP20190248A1
(ar)
|
2017-04-21 |
2019-10-20 |
Amgen Inc |
بروتينات ربط مولد ضد trem2 واستخداماته
|
|
EP3615564A1
(en)
|
2017-04-24 |
2020-03-04 |
Alexion Pharmaceuticals, Inc. |
Antibody immune cell inhibitor fusion proteins
|
|
WO2018201087A1
(en)
|
2017-04-27 |
2018-11-01 |
Seattle Genetics, Inc. |
Quaternized nicotinamide adenine dinucleotide salvage pathway inhibitor conjugates
|
|
US11021537B2
(en)
|
2017-05-01 |
2021-06-01 |
Agenus Inc. |
Anti-TIGIT antibodies and methods of use thereof
|
|
US11168129B2
(en)
|
2017-05-15 |
2021-11-09 |
University Of Rochester |
Broadly neutralizing anti-influenza human monoclonal antibody and uses thereof
|
|
CN111107868A
(zh)
|
2017-05-24 |
2020-05-05 |
诺华股份有限公司 |
抗体细胞因子移植蛋白及使用方法
|
|
JOP20190271A1
(ar)
|
2017-05-24 |
2019-11-21 |
Novartis Ag |
بروتينات مطعّمة بسيتوكين- الجسم المضاد وطرق الاستخدام للاضطرابات المتعلقة بالمناعة
|
|
WO2018215937A1
(en)
|
2017-05-24 |
2018-11-29 |
Novartis Ag |
Interleukin-7 antibody cytokine engrafted proteins and methods of use in the treatment of cancer
|
|
IL322309A
(en)
|
2017-05-24 |
2025-09-01 |
Novartis Ag |
IL2 antibody grafted proteins and methods of use in cancer treatment
|
|
MX2019013132A
(es)
|
2017-05-25 |
2020-01-27 |
Bristol Myers Squibb Co |
Anticuerpos que comprenden regiones constantes pesadas modificadas.
|
|
WO2018229715A1
(en)
|
2017-06-16 |
2018-12-20 |
Novartis Ag |
Compositions comprising anti-cd32b antibodies and methods of use thereof
|
|
MX2019015563A
(es)
|
2017-06-20 |
2020-07-28 |
Teneoone Inc |
Anticuerpos anti-bcma unicamente de cadena pesada.
|
|
CN110891971B
(zh)
|
2017-06-20 |
2024-01-12 |
特尼奥生物股份有限公司 |
仅有重链的抗bcma抗体
|
|
IL271837B2
(en)
|
2017-07-07 |
2024-01-01 |
Hanmi Pharm Ind Co Ltd |
Novel therapeutic enzyme fusion protein and use thereof
|
|
GB201711809D0
(en)
|
2017-07-21 |
2017-09-06 |
Governors Of The Univ Of Alberta |
Antisense oligonucleotide
|
|
KR20230066126A
(ko)
|
2017-07-27 |
2023-05-12 |
알렉시온 파마슈티칼스, 인코포레이티드 |
고농도 항-c5 항체 제형
|
|
BR112020003533A2
(pt)
|
2017-08-25 |
2020-11-17 |
Five Prime Therapeutics, Inc. |
anticorpos b7-h4 e métodos de uso dos mesmos
|
|
EP3676289B1
(en)
|
2017-08-28 |
2026-03-04 |
Altor BioScience, LLC |
Il-15-based fusions to il-7 and il-21
|
|
CA3075399A1
(en)
|
2017-09-13 |
2019-03-21 |
Teneobio, Inc. |
Heavy chain antibodies binding to ectoenzymes
|
|
KR102681143B1
(ko)
|
2017-09-28 |
2024-07-04 |
한미약품 주식회사 |
글루카곤 유사 펩타이드-2(glp-2) 유도체의 지속형 결합체
|
|
KR20190036956A
(ko)
|
2017-09-28 |
2019-04-05 |
한미약품 주식회사 |
지속형 단쇄 인슐린 아날로그 및 이의 결합체
|
|
JP7377195B2
(ja)
|
2017-09-29 |
2023-11-09 |
ハンミ ファーマシューティカル カンパニー リミテッド |
リンカーとして非ペプチド性重合体結合脂肪酸誘導体化合物を含むタンパク質結合体及びその製造方法
|
|
WO2019066603A1
(ko)
|
2017-09-29 |
2019-04-04 |
한미약품 주식회사 |
효력이 향상된 지속성 단백질 결합체
|
|
CN111655268B
(zh)
|
2017-10-04 |
2024-03-26 |
艾维迪提生物科学公司 |
核酸-多肽组合物及其用途
|
|
EP3694552A1
(en)
|
2017-10-10 |
2020-08-19 |
Tilos Therapeutics, Inc. |
Anti-lap antibodies and uses thereof
|
|
US10640508B2
(en)
|
2017-10-13 |
2020-05-05 |
Massachusetts Institute Of Technology |
Diazene directed modular synthesis of compounds with quaternary carbon centers
|
|
EP3694889A1
(en)
|
2017-10-13 |
2020-08-19 |
Boehringer Ingelheim International GmbH |
Human antibodies to thomsen-nouvelle (tn) antigen
|
|
WO2019081983A1
(en)
|
2017-10-25 |
2019-05-02 |
Novartis Ag |
CD32B TARGETING ANTIBODIES AND METHODS OF USE
|
|
MX2020004284A
(es)
|
2017-10-26 |
2020-10-28 |
Alexion Pharma Inc |
Dosis y administracion de anticuerpos anti-c5 para el tratamiento de la hemoglobinuria paroxistica nocturna (hpn) y el sindrome hemolitico uremico atipico (shua).
|
|
US10538583B2
(en)
|
2017-10-31 |
2020-01-21 |
Staten Biotechnology B.V. |
Anti-APOC3 antibodies and compositions thereof
|
|
SG11202003980PA
(en)
|
2017-10-31 |
2020-05-28 |
Staten Biotechnology B V |
Anti-apoc3 antibodies and methods of use thereof
|
|
EP3710589A4
(en)
|
2017-11-14 |
2021-11-10 |
Chugai Seiyaku Kabushiki Kaisha |
ANTI-C1S ANTIBODIES AND METHOD OF USING
|
|
CN118638787A
(zh)
|
2017-12-06 |
2024-09-13 |
艾维迪提生物科学公司 |
治疗肌萎缩和强直性肌营养不良的组合物和方法
|
|
CA3081144A1
(en)
|
2017-12-08 |
2019-06-13 |
Argenx Bvba |
Use of fcrn antagonists for treatment of generalized myasthenia gravis
|
|
BR112020012346A2
(pt)
|
2017-12-22 |
2020-11-24 |
Hanmi Pharm. Co., Ltd. |
proteína de fusão enzimática terapêutica tendo uma nova estrutura e uso da mesma
|
|
CA3086665A1
(en)
|
2017-12-22 |
2019-06-27 |
Teneobio, Inc. |
Heavy chain antibodies binding to cd22
|
|
IL275499B2
(en)
|
2017-12-22 |
2024-03-01 |
Novartis Ag |
Methods of treating metabolic disorders with fgf21 variants
|
|
WO2019133761A1
(en)
*
|
2017-12-27 |
2019-07-04 |
Teneobio, Inc. |
Cd3-delta/epsilon heterodimer specific antibodies
|
|
WO2019129054A1
(zh)
|
2017-12-27 |
2019-07-04 |
信达生物制药(苏州)有限公司 |
三链抗体、其制备方法及其用途
|
|
CN111788227B
(zh)
|
2017-12-27 |
2025-02-25 |
百时美施贵宝公司 |
抗cd40抗体及其用途
|
|
KR20250078626A
(ko)
|
2018-01-12 |
2025-06-02 |
브리스톨-마이어스 스큅 컴퍼니 |
Tim3에 대한 항체 및 그의 용도
|
|
US10738110B2
(en)
|
2018-01-12 |
2020-08-11 |
Amgen Inc. |
PAC1 antibodies and uses thereof
|
|
IL276546B2
(en)
|
2018-02-20 |
2024-08-01 |
Seagen Inc |
Hydrophobic auristatin F compounds and their conjugates
|
|
CN111741978A
(zh)
|
2018-02-21 |
2020-10-02 |
戊瑞治疗有限公司 |
B7-h4抗体制剂
|
|
WO2019169314A1
(en)
*
|
2018-03-01 |
2019-09-06 |
Igm Biosciences, Inc. |
IgM Fc AND J-CHAIN MUTATIONS THAT AFFECT IgM SERUM HALF-LIFE
|
|
EP3759142A1
(en)
|
2018-03-02 |
2021-01-06 |
Five Prime Therapeutics, Inc. |
B7-h4 antibodies and methods of use thereof
|
|
BR112020018539A2
(pt)
|
2018-03-23 |
2020-12-29 |
Bristol-Myers Squibb Company |
Anticorpos contra mica e/ou micb e usos dos mesmos
|
|
US11168138B2
(en)
|
2018-03-26 |
2021-11-09 |
Altor Bioscience, Llc |
Anti-PDL1, IL-15 and TGF-beta receptor combination molecules
|
|
WO2019184909A1
(zh)
|
2018-03-27 |
2019-10-03 |
信达生物制药(苏州)有限公司 |
新型抗体分子、其制备方法及其用途
|
|
CN110305210B
(zh)
|
2018-03-27 |
2023-02-28 |
信达生物制药(苏州)有限公司 |
新型抗体分子、其制备方法及其用途
|
|
WO2019190293A1
(ko)
|
2018-03-30 |
2019-10-03 |
한미약품 주식회사 |
뇌 표적 지속성 단백질 결합체, 이의 제조 방법, 및 이를 포함하는 조성물
|
|
TWI790370B
(zh)
|
2018-04-02 |
2023-01-21 |
美商必治妥美雅史谷比公司 |
抗trem-1抗體及其用途
|
|
CN110396133B
(zh)
|
2018-04-25 |
2021-07-23 |
免疫靶向有限公司 |
一种以白介素12为活性成分的融合蛋白型药物前体
|
|
WO2019209078A1
(ko)
|
2018-04-26 |
2019-10-31 |
주식회사 굳티셀 |
신규한 융합 단백질 및 이를 포함하는 암의 예방 또는 치료용 약학적 조성물
|
|
WO2019213384A1
(en)
|
2018-05-03 |
2019-11-07 |
University Of Rochester |
Anti-influenza neuraminidase monoclonal antibodies and uses thereof
|
|
AU2019265699B2
(en)
|
2018-05-08 |
2026-03-12 |
Amgen Inc. |
Bispecific antibodies with cleavable C-terminal charge-paired tags
|
|
TWI869346B
(zh)
|
2018-05-30 |
2025-01-11 |
瑞士商諾華公司 |
Ｅｎｔｐｄ２抗體、組合療法、及使用該等抗體和組合療法之方法
|
|
ES2996257T3
(en)
|
2018-05-31 |
2025-02-12 |
Alexion Pharma Inc |
Dosage and administration of anti-c5 antibodies for treatment of paroxysmal nocturnal hemoglobinuria (pnh) in pediatric patients
|
|
KR20250151605A
(ko)
|
2018-06-01 |
2025-10-21 |
노파르티스 아게 |
Bcma에 대한 결합 분자 및 이의 용도
|
|
US12460012B2
(en)
|
2018-06-04 |
2025-11-04 |
Alexion Pharmaceuticals, Inc. |
Dosage and administration of anti-C5 antibodies for treatment of atypical hemolytic uremic syndrome (aHUS) in pediatric patients
|
|
TW202519270A
(zh)
|
2018-06-07 |
2025-05-16 |
美商思進公司 |
喜樹鹼結合物
|
|
MY209122A
(en)
|
2018-06-08 |
2025-06-23 |
argenx BV |
Compositions and methods for treating immune thrombocytopenia
|
|
TWI848953B
(zh)
|
2018-06-09 |
2024-07-21 |
德商百靈佳殷格翰國際股份有限公司 |
針對癌症治療之多特異性結合蛋白
|
|
AU2019287623B2
(en)
|
2018-06-15 |
2024-11-07 |
Amyl Therapeutics Srl |
General amyloid interaction motif (GAIM)
|
|
CN112638406B
(zh)
|
2018-06-22 |
2025-04-22 |
科优基因公司 |
白介素-2变体及其使用方法
|
|
WO2020006266A1
(en)
|
2018-06-28 |
2020-01-02 |
Alexion Pharmaceuticals, Inc. |
Methods of producing anti-c5 antibodies
|
|
SG11202011597RA
(en)
|
2018-07-20 |
2020-12-30 |
Teneobio Inc |
Heavy chain antibodies binding to cd19
|
|
MA53160A
(fr)
|
2018-07-20 |
2021-05-26 |
Pf Medicament |
Récepteur pour vista
|
|
AU2019309472A1
(en)
|
2018-07-24 |
2021-03-18 |
Good T Cells, Inc. |
Composition for preventing or treating immune-related diseases
|
|
AU2019316103B2
(en)
|
2018-08-02 |
2026-02-19 |
Dyne Therapeutics, Inc. |
Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
|
|
KR102697702B1
(ko)
|
2018-08-10 |
2024-08-22 |
추가이 세이야쿠 가부시키가이샤 |
항cd137 항원 결합 분자 및 그의 사용
|
|
WO2020037120A1
(en)
|
2018-08-16 |
2020-02-20 |
Nantbio, Inc. |
Il7-il15 txm compositions and methods
|
|
BR112021004680A2
(pt)
|
2018-09-21 |
2021-08-31 |
Teneobio, Inc. |
Métodos para purificar anticorpos multiespecíficos heterodiméricos
|
|
CN110964116A
(zh)
|
2018-09-26 |
2020-04-07 |
北京辅仁瑞辉生物医药研究院有限公司 |
GLP1-Fc融合蛋白及其缀合物
|
|
PE20211491A1
(es)
|
2018-09-27 |
2021-08-11 |
Celgene Corp |
PROTEINAS DE FIJACION A SIRPa Y METODOS DE USO DE ESTAS
|
|
EP3860713A2
(en)
|
2018-10-03 |
2021-08-11 |
Staten Biotechnology B.V. |
Antibodies specific for human and cynomolgus apoc3 and methods of use thereof
|
|
KR20200038878A
(ko)
|
2018-10-04 |
2020-04-14 |
한미약품 주식회사 |
글루카곤 및 이를 포함하는 조합물의 치료학적 용도
|
|
WO2020074544A1
(en)
|
2018-10-10 |
2020-04-16 |
Novo Nordisk A/S |
Oligomer extended insulin-fc conjugates and their medical use
|
|
US11130802B2
(en)
|
2018-10-10 |
2021-09-28 |
Tilos Therapeutics, Inc. |
Anti-lap antibody variants
|
|
UY38407A
(es)
|
2018-10-15 |
2020-05-29 |
Novartis Ag |
Anticuerpos estabilizadores de trem2
|
|
TWI824043B
(zh)
|
2018-10-25 |
2023-12-01 |
西班牙商瑪製藥股份有限公司 |
藥物抗體共軛物
|
|
MX2021004732A
(es)
|
2018-10-26 |
2021-06-04 |
Teneobio Inc |
Anticuerpos de cadena pesada que se unen a cd38.
|
|
KR102467349B1
(ko)
|
2018-10-29 |
2022-11-16 |
에프. 호프만-라 로슈 아게 |
항체 제형
|
|
AU2019370295A1
(en)
|
2018-10-30 |
2021-06-03 |
Alexion Pharmaceuticals, Inc. |
Subcutaneous dosage and administration of anti-C5 antibodies for treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH)
|
|
MY205758A
(en)
|
2018-11-16 |
2024-11-12 |
Bristol Myers Squibb Co |
Anti-nkg2a antibodies and uses thereof
|
|
US20220106400A1
(en)
|
2018-11-28 |
2022-04-07 |
Bristol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
|
IL319265A
(en)
|
2018-12-21 |
2025-04-01 |
Avidity Biosciences Inc |
Anti-transferrin receptor antibodies and their uses
|
|
KR20200078413A
(ko)
|
2018-12-21 |
2020-07-01 |
한미약품 주식회사 |
글루카곤, glp-1 및 gip 수용체 모두에 활성을 갖는 삼중 활성체 및 인슐린을 포함하는 약학 조성물
|
|
WO2020130751A1
(ko)
|
2018-12-21 |
2020-06-25 |
한미약품 주식회사 |
인슐린 및 글루카곤을 포함하는 약학 조성물
|
|
KR20230128134A
(ko)
|
2019-01-22 |
2023-09-01 |
브리스톨-마이어스 스큅 컴퍼니 |
Il-7r 알파 서브유닛에 대한 항체 및 이의 용도
|
|
CN113874081A
(zh)
|
2019-02-26 |
2021-12-31 |
茵思博纳公司 |
高-亲和力抗-mertk抗体及其用途
|
|
AU2020252556B2
(en)
|
2019-04-05 |
2026-02-05 |
Teneobio, Inc. |
Heavy chain antibodies binding to PSMA
|
|
KR102524577B1
(ko)
|
2019-04-22 |
2023-04-21 |
전남대학교산학협력단 |
플라젤린 융합 단백질 및 이의 용도
|
|
EP3959319A4
(en)
|
2019-04-25 |
2023-06-07 |
Avidity Biosciences, Inc. |
NUCLEIC ACID COMPOSITIONS AND METHODS FOR MULTI-EXON SKIPPING
|
|
US12134655B2
(en)
|
2019-04-30 |
2024-11-05 |
Absci Corporation |
Cancer associated antibody compositions and methods of use
|
|
CA3139809A1
(en)
|
2019-05-10 |
2020-11-19 |
Takeda Pharmaceutical Company Limited |
Antibody drug conjugates
|
|
BR112021021689A2
(pt)
|
2019-05-15 |
2022-03-22 |
Chugai Pharmaceutical Co Ltd |
Molécula de ligação a antígeno, composição farmacêutica, e método
|
|
US12037378B2
(en)
|
2019-05-21 |
2024-07-16 |
Novartis Ag |
Variant CD58 domains and uses thereof
|
|
TWI905099B
(zh)
|
2019-05-21 |
2025-11-21 |
瑞士商諾華公司 |
Cd19 結合分子及其用途
|
|
US11827671B2
(en)
|
2019-05-24 |
2023-11-28 |
Sanofi |
Methods for treating systemic sclerosis
|
|
WO2020243477A2
(en)
|
2019-05-30 |
2020-12-03 |
Amgen Inc. |
Engineering the hinge region to drive antibody dimerization
|
|
JP7581252B2
(ja)
|
2019-06-06 |
2024-11-12 |
アビディティー バイオサイエンシーズ，インク． |
Ｕｎａアミダイトおよびその使用
|
|
US11578090B2
(en)
|
2019-06-06 |
2023-02-14 |
Avidity Biosciences, Inc. |
Nucleic acid-polypeptide compositions and uses thereof
|
|
CN114126647A
(zh)
|
2019-06-07 |
2022-03-01 |
阿尔金克斯有限公司 |
适用于皮下施用的FcRn抑制剂的药物制剂
|
|
CR20210622A
(es)
|
2019-06-14 |
2022-06-27 |
Teneobio Inc |
Anticuerpos multiespecíficos de cadena pesada que se unen a cd22 y cd3
|
|
JP7756001B2
(ja)
|
2019-06-28 |
2025-10-17 |
アムジエン・インコーポレーテツド |
抗ｃｇｒｐ受容体／抗ｐａｃ１受容体二重特異性抗原結合タンパク質
|
|
EP4311578A3
(en)
|
2019-06-28 |
2024-04-10 |
Hanmi Pharm. Co., Ltd. |
Triple agonist having activity with respect to all of glucagon, glp-1, and gip receptors for treating liver disease
|
|
WO2021011678A1
(en)
|
2019-07-15 |
2021-01-21 |
Bristol-Myers Squibb Company |
Anti-trem-1 antibodies and uses thereof
|
|
WO2021011681A1
(en)
|
2019-07-15 |
2021-01-21 |
Bristol-Myers Squibb Company |
Antibodies against human trem-1 and uses thereof
|
|
KR102478588B1
(ko)
|
2019-07-18 |
2022-12-16 |
한미약품 주식회사 |
신규 중간체 제조를 통한 지속형 약물 결합체의 제조 방법
|
|
WO2021010531A1
(ko)
|
2019-07-18 |
2021-01-21 |
한미약품 주식회사 |
단백질 결합체의 신규 제조 방법
|
|
JP2022542431A
(ja)
|
2019-07-30 |
2022-10-03 |
キューエルエスエフ バイオセラピューティクス， インコーポレイテッド |
二重特異性抗ｌｒｒｃ１５及びｃｄ３イプシロン抗体
|
|
AU2020329217A1
(en)
|
2019-08-12 |
2022-07-28 |
Aptevo Research And Development Llc |
4-1BB and OX40 binding proteins and related compositions and methods, antibodies against 4-1BB, antibodies against OX40
|
|
AU2020335928A1
(en)
|
2019-08-30 |
2022-02-17 |
Agenus Inc. |
Anti-CD96 antibodies and methods of use thereof
|
|
TW202122116A
(zh)
|
2019-09-05 |
2021-06-16 |
西班牙商瑪製藥股份有限公司 |
藥物抗體偶聯物
|
|
WO2021053559A1
(en)
|
2019-09-18 |
2021-03-25 |
Novartis Ag |
Entpd2 antibodies, combination therapies, and methods of using the antibodies and combination therapies
|
|
TW202124446A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
與ｅｎｔｐｄ２抗體之組合療法
|
|
KR20220084056A
(ko)
|
2019-09-19 |
2022-06-21 |
씨젠 인크. |
내재화된 생물학적 활성 화합물 컨쥬게이트로부터의 선택적 약물 방출
|
|
WO2021067820A1
(en)
|
2019-10-04 |
2021-04-08 |
Seagen Inc. |
Formulation of antibody-drug conjugate
|
|
KR20220079606A
(ko)
|
2019-10-04 |
2022-06-13 |
씨젠 인크. |
캄프토테신 펩티드 접합체
|
|
CN114786706A
(zh)
|
2019-10-04 |
2022-07-22 |
韩美药品株式会社 |
胰高血糖素、包含glp-1受体和gip受体双重激动剂的组合物、及其治疗用途
|
|
US20220380487A1
(en)
|
2019-10-24 |
2022-12-01 |
Minotaur Therapeutics, Inc. |
Chimeric cytokine modified antibodies and methods of use thereof
|
|
CA3160482A1
(en)
|
2019-11-08 |
2021-05-14 |
Amgen Inc. |
Engineering charge pair mutations for pairing of hetero-igg molecules
|
|
MX2022005965A
(es)
|
2019-11-19 |
2022-08-08 |
Amgen Inc |
Formato de anticuerpos multiespecíficos novedosos.
|
|
JP7807076B2
(ja)
|
2019-12-13 |
2026-01-27 |
キュージーン インコーポレイテッド |
新規インターロイキン－１５（ｉｌ－１５）融合タンパク質およびその使用
|
|
WO2021127489A1
(en)
|
2019-12-18 |
2021-06-24 |
Teneobio, Inc. |
Heavy chain antibodies binding to cd38
|
|
GB201919061D0
(en)
|
2019-12-20 |
2020-02-05 |
Ucb Biopharma Sprl |
Multi-specific antibody
|
|
AU2020405230A1
(en)
|
2019-12-20 |
2022-06-23 |
Amgen Inc. |
Mesothelin-targeted CD40 agonistic multispecific antibody constructs for the treatment of solid tumors
|
|
EP4082561A4
(en)
|
2019-12-24 |
2024-02-07 |
Hanmi Pharm. Co., Ltd. |
Pharmaceutical composition for preventing or treating metabolic bone diseases, comprising glp-2 or conjugate thereof
|
|
ES2992247T3
(es)
|
2020-01-08 |
2024-12-11 |
argenx BV |
Antagonistas del receptor de Fc neonatal humano (FcRn) para el tratamiento de trastornos del pénfigo
|
|
AU2020423596A1
(en)
|
2020-01-13 |
2022-09-08 |
Hanmi Pharm. Co., Ltd. |
Therapeutic use of long-acting conjugate of triple agonist having activity with respect to all of glucagon and GLP-1 and GIP receptors against lung disease
|
|
BR112022017064A2
(pt)
|
2020-02-25 |
2022-11-16 |
Mediboston Inc |
Derivados da camptotecina e seus conjugados
|
|
AU2021237465A1
(en)
|
2020-03-19 |
2022-10-13 |
Avidity Biosciences, Inc. |
Compositions and methods of treating Facioscapulohumeral muscular dystrophy
|
|
US11365239B2
(en)
|
2020-03-20 |
2022-06-21 |
Tsb Therapeutics (Beijing) Co., Ltd. |
Anti-SARS-COV-2 antibodies and uses thereof
|
|
DK4045533T5
(da)
|
2020-03-26 |
2024-07-29 |
Univ Vanderbilt |
Humane monoklonale antistoffer mod svær akut respiratorisk syndrom-coronavirus 2 (sars-cov-2)
|
|
EP4127173A4
(en)
*
|
2020-03-27 |
2024-07-17 |
Alnylam Pharmaceuticals, Inc. |
IGG FC FRAGMENT RECEIVER AND TRANSPORTER (FCGRT) ARNI COMPOSITIONS AND METHODS OF USE THEREOF
|
|
IL296393B1
(en)
|
2020-03-27 |
2025-12-01 |
Avidity Biosciences Inc |
Compositions and methods of treating muscle dystrophy
|
|
KR20210121585A
(ko)
|
2020-03-30 |
2021-10-08 |
한국세라믹기술원 |
반응성 및 안정성 그리고 항체회수가 향상된 z-도메인 및 칼시퀘스트린 융합단백질 및 이를 이용한 항체의 분리 및 정제 방법
|
|
EP4126934A1
(en)
|
2020-04-01 |
2023-02-08 |
University of Rochester |
Monoclonal antibodies against the hemagglutinin (ha) and neuraminidase (na) of influenza h3n2 viruses
|
|
BR112022019518A2
(pt)
|
2020-04-03 |
2023-02-07 |
Hanmi Pharm Ind Co Ltd |
Composição farmacêutica para prevenir ou tratar mucosite induzida por radioterapia, quimioterapia, ou uma combinação das mesmas, que compreende derivados de glp-2 ou um conjugado de atuação duradoura do mesmo
|
|
CN121577898A
(zh)
*
|
2020-04-08 |
2026-02-27 |
豪夫迈·罗氏有限公司 |
大分子非特异性清除测定
|
|
EP4132971A1
(en)
|
2020-04-09 |
2023-02-15 |
Merck Sharp & Dohme LLC |
Affinity matured anti-lap antibodies and uses thereof
|
|
WO2021216458A1
(en)
|
2020-04-20 |
2021-10-28 |
Genzyme Corporation |
Humanized anti-complement factor bb antibodies and uses thereof
|
|
WO2021215801A1
(ko)
|
2020-04-20 |
2021-10-28 |
한미약품 주식회사 |
글루카곤, glp-1 및 gip 수용체 모두에 활성을 갖는 삼중 활성체 또는 이의 결합체를 포함하는 고지혈증 예방 또는 치료용 약학적 조성물 및 예방 또는 치료 방법
|
|
BR112022020823A2
(pt)
|
2020-04-21 |
2022-11-29 |
Pharma Mar Sa |
Conjugados de fármaco e anticorpo
|
|
KR20230002261A
(ko)
|
2020-04-28 |
2023-01-05 |
더 락커펠러 유니버시티 |
항-sars-cov-2 중화 항체 및 이의 사용 방법
|
|
MX2022013453A
(es)
|
2020-04-29 |
2022-11-16 |
Teneobio Inc |
Anticuerpos de cadena pesada multiespecificos con regiones constantes de cadena pesada modificadas.
|
|
AU2021263926A1
(en)
|
2020-04-29 |
2023-01-19 |
Teneoone, Inc. |
Methods of treating multiple myeloma
|
|
UY40898A
(es)
|
2020-04-29 |
2024-10-15 |
Teneobio Inc |
Anticuerpos de cadena pesada multiespecíficos con regiones constantes de cadena pesada modificadas
|
|
CA3177830A1
(en)
|
2020-05-13 |
2021-11-18 |
Maria BECONI |
Anti-hemojuvelin (hjv) antibodies for treating myelofibrosis
|
|
US20230192867A1
(en)
|
2020-05-15 |
2023-06-22 |
Bristol-Myers Squibb Company |
Antibodies to garp
|
|
EP4153312A1
(en)
|
2020-05-17 |
2023-03-29 |
AstraZeneca UK Limited |
Sars-cov-2 antibodies and methods of selecting and using the same
|
|
EP4154869A4
(en)
|
2020-05-22 |
2025-01-22 |
Hanmi Pharm. Co., Ltd. |
Liquid formulation of long-acting conjugate of glp-2
|
|
BR112022023609A2
(pt)
|
2020-05-22 |
2023-02-07 |
Hanmi Pharm Ind Co Ltd |
Formulação líquida de conjugado de ação prolongada de agonista trigonal de glucagon, glp-1 e gip
|
|
CN115803015A
(zh)
|
2020-05-22 |
2023-03-14 |
韩美药品株式会社 |
胰高血糖素衍生物的长效缀合物的液体制剂
|
|
CA3179707A1
(en)
|
2020-05-22 |
2021-11-25 |
Ji Hye Moon |
Liquid formulation
|
|
US20230265145A1
(en)
|
2020-06-26 |
2023-08-24 |
Amgen Inc. |
Il-10 muteins and fusion proteins thereof
|
|
IL299027A
(en)
|
2020-06-30 |
2023-02-01 |
Teneobio Inc |
Multispecific antibodies that bind BCMA
|
|
JP2023534949A
(ja)
|
2020-07-15 |
2023-08-15 |
ハンミ ファーマシューティカル カンパニー リミテッド |
グルカゴン誘導体又はその結合体の肝臓疾患に対する治療的用途
|
|
JP2023535382A
(ja)
|
2020-07-17 |
2023-08-17 |
ハンミ ファーマシューティカル カンパニー リミテッド |
三重作用性持続型結合体又は三重作用剤を含む組合せ物の治療学的用途
|
|
WO2022015710A1
(en)
|
2020-07-17 |
2022-01-20 |
Spectrum Pharmaceuticals, Inc. |
Methods of treating chemotherapy induced neutropenia using fixed doses of g-csf protein complex
|
|
US20230272030A1
(en)
|
2020-07-24 |
2023-08-31 |
Jiangsu Gensciences Inc. |
Insulin-fc fusion protein and application thereof
|
|
TW202212354A
(zh)
|
2020-08-03 |
2022-04-01 |
美商健生生物科技公司 |
用於病毒治療劑中之多向生物運輸的材料及方法
|
|
MX2023001492A
(es)
|
2020-08-06 |
2023-03-08 |
Bioverativ Usa Inc |
Citocinas inflamatorias y fatiga en sujetos con una enfermedad mediada por el complemento.
|
|
US20220041694A1
(en)
|
2020-08-10 |
2022-02-10 |
Astrazeneca Uk Limited |
Sars-cov-2 antibodies for treatment and prevention of covid-19
|
|
JP2023537895A
(ja)
|
2020-08-14 |
2023-09-06 |
ハンミ ファーマシューティカル カンパニー リミテッド |
三重活性体持続型結合体を有効成分として含む薬学組成物
|
|
EP4197550A4
(en)
|
2020-08-14 |
2025-10-08 |
Hanmi Pharmaceutical Co Ltd |
PHARMACEUTICAL COMPOSITION WITH HYPOTENSIVE EFFECT COMPRISING A TRIPLE ACTIVATOR WITH ACTIVITY FOR ALL GLUCAGON, GLP-1, AND GIP RECEPTORS
|
|
AU2021329374A1
(en)
|
2020-08-20 |
2023-03-09 |
Amgen Inc. |
Antigen binding proteins with non-canonical disulfide in FAB region
|
|
KR20220041766A
(ko)
|
2020-09-25 |
2022-04-01 |
한미약품 주식회사 |
글루카곤, glp-1 및 gip 수용체 모두에 활성을 갖는 삼중 활성체의 지속형 결합체의 다발성 경화증의 치료 용도
|
|
EP4218791A4
(en)
|
2020-09-25 |
2024-11-06 |
Hanmi Pharm. Co., Ltd. |
THERAPEUTIC USE OF TRIPLE AGONISTS WITH ACTIVITY TOWARDS ALL GLUCAGON, GLP-1 AND GIP RECEPTORS FOR NEURODEGENERATIVE DISEASES OR CONJUGATES THEREOF
|
|
US20230355720A1
(en)
|
2020-09-25 |
2023-11-09 |
Hanmi Pharm. Co., Ltd. |
Pharmaceutical composition for preventing or treating bone diseases, comprising triple agonist or conjugate thereof having activity with respect to all of glucagon, glp-1 and glp receptors
|
|
US20230374162A1
(en)
|
2020-10-07 |
2023-11-23 |
Amgen Inc. |
Rational selection of building blocks for the assembly of multispecific antibodies
|
|
KR20220050824A
(ko)
|
2020-10-16 |
2022-04-25 |
한미약품 주식회사 |
글루카곤, glp-1 및 gip 수용체 모두에 활성을 갖는 삼중 활성체의 호흡기 감염 질환의 후유증의 치료 용도
|
|
KR20220050819A
(ko)
|
2020-10-16 |
2022-04-25 |
한미약품 주식회사 |
Gip 유도체 또는 이의 지속형 결합체를 포함하는 루푸스-관련 질환의 예방 또는 치료용 약학적 조성물
|
|
CN116583533A
(zh)
|
2020-10-16 |
2023-08-11 |
韩美药品株式会社 |
Gip衍生物、其长效缀合物和包括其的药物组合物
|
|
CN116670169A
(zh)
|
2020-10-16 |
2023-08-29 |
魁尔斯弗生物治疗股份有限公司 |
与pd-l1结合的多特异性结合化合物
|
|
WO2022080986A1
(ko)
|
2020-10-16 |
2022-04-21 |
한미약품 주식회사 |
Glp-1/gip 이중작용제, 이의 지속형 결합체, 및 이를 포함하는 약학적 조성물
|
|
KR20220050822A
(ko)
|
2020-10-16 |
2022-04-25 |
한미약품 주식회사 |
글루카곤/glp-1/gip 삼중작용제 또는 이의 지속형 결합체를 포함하는 루푸스-관련 질환의 예방 또는 치료용 약학적 조성물
|
|
EP4230218A4
(en)
|
2020-10-16 |
2024-11-20 |
Hanmi Pharm. Co., Ltd. |
Pharmaceutical composition comprising glucagon/glp-1/gip triple agonist or long-acting conjugate thereof for preventing or treating vasculitis
|
|
WO2022098870A1
(en)
|
2020-11-04 |
2022-05-12 |
The Rockefeller University |
Neutralizing anti-sars-cov-2 antibodies
|
|
IL302569A
(en)
|
2020-11-06 |
2023-07-01 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
|
EP4240488A1
(en)
|
2020-11-09 |
2023-09-13 |
Takeda Pharmaceutical Company Limited |
Antibody drug conjugates
|
|
JP2023548595A
(ja)
|
2020-11-10 |
2023-11-17 |
アムジエン・インコーポレーテツド |
多重特異性抗原結合ドメインの新規のリンカー
|
|
EP4245311A4
(en)
|
2020-11-13 |
2024-10-30 |
Hanmi Pharm. Co., Ltd. |
USE OF A THERAPEUTIC ENZYMFUSION PROTEIN FOR THE PREVENTION AND TREATMENT OF KIDNEY DISEASE CAUSED BY OR ASSOCIATED WITH FABRY DISEASE
|
|
AU2021377712A1
(en)
|
2020-11-13 |
2023-06-01 |
Hanmi Pharm. Co., Ltd. |
Use of therapeutic enzyme fusion protein in prevention and treatment of neuropathy caused by or accompanied by Fabry disease
|
|
TW202233684A
(zh)
|
2020-11-18 |
2022-09-01 |
美商泰尼歐生物公司 |
結合於葉酸受體α之重鏈抗體
|
|
US20240301086A1
(en)
|
2020-12-01 |
2024-09-12 |
Aptevo Research And Development Llc |
Tumor-associated antigens and cd3-binding proteins, related compositions, and methods
|
|
EP4255926A1
(en)
|
2020-12-07 |
2023-10-11 |
UCB Biopharma SRL |
Multi-specific antibodies and antibody combinations
|
|
KR20220086522A
(ko)
|
2020-12-16 |
2022-06-23 |
주식회사 굳티셀 |
Taci 단백질의 용도
|
|
EP4269425A4
(en)
|
2020-12-24 |
2024-11-27 |
Hanmi Pharm. Co., Ltd. |
NEW TRIPLE ACTIVATOR ACTIVATING ALL GLUCAGON, GLP-1 AND GIP RECEPTORS AND ITS USE
|
|
US20240299500A1
(en)
|
2020-12-24 |
2024-09-12 |
Hanmi Pharm Co., Ltd. |
Combination therapy of insulinotropic peptide and glp-2, for preventing or treating short bowel syndrome
|
|
KR20230128050A
(ko)
|
2020-12-31 |
2023-09-01 |
다인 세라퓨틱스, 인크. |
근육 표적화 복합체 및 근긴장성 이영양증을 치료하기위한 그의 용도
|
|
EP4271482A2
(en)
|
2020-12-31 |
2023-11-08 |
Alamar Biosciences, Inc. |
Binder molecules with high affinity and/ or specificity and methods of making and use thereof
|
|
EP4277926A1
(en)
|
2021-01-15 |
2023-11-22 |
The Rockefeller University |
Neutralizing anti-sars-cov-2 antibodies
|
|
JP2024505943A
(ja)
|
2021-01-29 |
2024-02-08 |
ハンミ ファーマシューティカルズ カンパニー リミテッド |
Ｇｉｐ誘導体、またはその持続型結合体を含む肺疾患の予防用または治療用の薬学的組成物
|
|
US12521444B2
(en)
|
2021-02-25 |
2026-01-13 |
Fortvita Biologics Limited |
Anti-HER2 antibody-drug conjugates and uses thereof
|
|
MX2023009874A
(es)
|
2021-02-25 |
2023-08-30 |
Teneobio Inc |
Anticuerpos anti-psma y estructuras car-t.
|
|
KR20230150825A
(ko)
|
2021-02-26 |
2023-10-31 |
테네오바이오, 인코포레이티드 |
항-muc1-c 항체 및 car-t 구조
|
|
KR20230158005A
(ko)
|
2021-03-18 |
2023-11-17 |
씨젠 인크. |
생물학적 활성 화합물의 내재화된 접합체로부터의 선택적 약물 방출
|
|
KR20230158006A
(ko)
|
2021-03-18 |
2023-11-17 |
씨젠 인크. |
생물학적 활성 화합물의 내재화된 접합체로부터의 선택적 약물 방출
|
|
WO2022212645A1
(en)
|
2021-03-31 |
2022-10-06 |
Bioverativ Usa Inc. |
Reducing surgery-associated hemolysis in cold agglutinin disease patients
|
|
IL304365B2
(en)
|
2021-03-31 |
2025-04-01 |
Hanmi Pharmaceutical Co Ltd |
A novel conjugate of an IL2 immunostimulatory analog and method of preparation thereof
|
|
JP2024514530A
(ja)
|
2021-04-02 |
2024-04-02 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
切断型ｃｄｃｐ１に対する抗体およびその使用
|
|
TW202304994A
(zh)
|
2021-04-02 |
2023-02-01 |
美商泰尼歐生物公司 |
促效性抗ｉｌ－２ｒ抗體及使用方法
|
|
AU2022255709A1
(en)
|
2021-04-06 |
2023-09-28 |
Teneobio, Inc. |
Anti-cd19 antibodies and car-t structures
|
|
JP2024512895A
(ja)
|
2021-04-09 |
2024-03-21 |
ハンミ ファーマシューティカル カンパニー リミテッド |
グルカゴン誘導体を含む慢性腎臓疾患予防又は治療用薬学組成物
|
|
CN117337303A
(zh)
|
2021-04-16 |
2024-01-02 |
特尼奥生物股份有限公司 |
抗cd20抗体及car-t结构
|
|
US20240182600A1
(en)
|
2021-04-20 |
2024-06-06 |
Amgen Inc. |
Balanced Charge Distribution in Electrostatic Steering of Chain Pairing in Multi-specific and Monovalent IgG Molecule Assembly
|
|
CN118251420A
(zh)
|
2021-04-28 |
2024-06-25 |
米诺陶治疗公司 |
人源化嵌合牛抗体和使用方法
|
|
EP4334343A2
(en)
|
2021-05-06 |
2024-03-13 |
The Rockefeller University |
Neutralizing anti-sars- cov-2 antibodies and methods of use thereof
|
|
WO2022263357A1
(en)
|
2021-06-14 |
2022-12-22 |
Argenx Iip Bv |
Anti-il-9 antibodies and methods of use thereof
|
|
WO2022271987A1
(en)
|
2021-06-23 |
2022-12-29 |
TeneoFour, Inc. |
Anti-cd38 antibodies and epitopes of same
|
|
US20240279332A1
(en)
|
2021-06-25 |
2024-08-22 |
Amgen Inc. |
Treatment of Cardiovascular Disease with TREM-1 Antigen Binding Proteins
|
|
KR20230004135A
(ko)
|
2021-06-30 |
2023-01-06 |
한미약품 주식회사 |
글루카곤, glp-1 및 gip 수용체 모두에 활성을 갖는 삼중 활성체를 포함하는 조합물의 치료학적 용도
|
|
WO2023004197A1
(en)
|
2021-07-23 |
2023-01-26 |
Teneoten, Inc. |
Heavy chain antibodies binding to hepatitis b surface antigen
|
|
US20230181671A1
(en)
|
2021-09-02 |
2023-06-15 |
Djs Antibodies Ltd |
Polypeptides
|
|
CN118265544A
(zh)
|
2021-09-16 |
2024-06-28 |
艾维迪提生物科学公司 |
治疗面肩肱型肌营养不良的组合物和方法
|
|
CN118541392A
(zh)
|
2021-09-28 |
2024-08-23 |
准星生物医药有限公司 |
多种形式的分子复合物
|
|
TW202330038A
(zh)
|
2021-09-30 |
2023-08-01 |
美商思進公司 |
用於治療癌症之ｂ７－ｈ４抗體－藥物結合物
|
|
IL312043A
(en)
|
2021-10-14 |
2024-06-01 |
Teneobio Inc |
Mesothelin binding proteins and their uses
|
|
TW202342095A
(zh)
|
2021-11-05 |
2023-11-01 |
英商阿斯特捷利康英國股份有限公司 |
用於治療和預防ｃｏｖｉｄ—１９之組成物
|
|
EP4433160A1
(en)
|
2021-11-17 |
2024-09-25 |
Disc Medicine, Inc. |
Methods for treating anemia of kidney disease
|
|
KR20230095666A
(ko)
|
2021-12-22 |
2023-06-29 |
한미약품 주식회사 |
간 표적 물질 및 이의 용도
|
|
KR20230095665A
(ko)
|
2021-12-22 |
2023-06-29 |
한미약품 주식회사 |
간 표적 약물 및 이의 용도
|
|
UY40097A
(es)
|
2022-01-07 |
2023-07-14 |
Johnson & Johnson Entpr Innovation Inc |
Materiales y métodos de proteínas de unión a il-1b
|
|
WO2023147399A1
(en)
|
2022-01-27 |
2023-08-03 |
The Rockefeller University |
Broadly neutralizing anti-sars-cov-2 antibodies targeting the n-terminal domain of the spike protein and methods of use thereof
|
|
TW202342510A
(zh)
|
2022-02-18 |
2023-11-01 |
英商Ｒｑ生物科技有限公司 |
抗體
|
|
US20250197448A1
(en)
|
2022-03-11 |
2025-06-19 |
University Of Rochester |
Cyclopeptibodies and uses thereof
|
|
PE20242179A1
(es)
|
2022-03-17 |
2024-11-07 |
Seagen Inc |
Conjugados de camptotecina
|
|
US12071621B2
(en)
|
2022-04-05 |
2024-08-27 |
Avidity Biosciences, Inc. |
Anti-transferrin receptor antibody-PMO conjugates for inducing DMD exon 44 skipping
|
|
KR20230149258A
(ko)
|
2022-04-18 |
2023-10-26 |
한미약품 주식회사 |
장질환의 예방 또는 치료를 위한 GLP-2와, 인슐린 분비 펩타이드, TNFα 억제제, 또는 이 둘 모두의 병용 요법
|
|
EP4514846A1
(en)
|
2022-04-26 |
2025-03-05 |
Novartis AG |
Multispecific antibodies targeting il-13 and il-18
|
|
CN119836433A
(zh)
|
2022-04-29 |
2025-04-15 |
阿斯利康(英国)有限公司 |
Sars-cov-2抗体及其使用方法
|
|
CA3258004A1
(en)
|
2022-06-15 |
2023-12-21 |
argenx BV |
FCRN/HSA BONDING MOLECULES AND METHODS OF USE
|
|
JP2025520434A
(ja)
|
2022-06-15 |
2025-07-03 |
バイオベラティブ・ユーエスエイ・インコーポレイテッド |
抗補体Ｃ１ｓ抗体製剤
|
|
WO2023250507A1
(en)
|
2022-06-24 |
2023-12-28 |
Bioverativ Usa Inc. |
Methods for treating complement-mediated diseases
|
|
EP4547710A1
(en)
|
2022-07-01 |
2025-05-07 |
ALK-Abelló A/S |
Displacers of ige-fceri
|
|
WO2024013727A1
(en)
|
2022-07-15 |
2024-01-18 |
Janssen Biotech, Inc. |
Material and methods for improved bioengineered pairing of antigen-binding variable regions
|
|
TW202412762A
(zh)
|
2022-07-27 |
2024-04-01 |
香港商祐方有限公司 |
奧瑞他汀衍生物及其結合物
|
|
JP2025524899A
(ja)
|
2022-07-27 |
2025-08-01 |
テネオバイオ， インコーポレイテッド |
メソテリン結合タンパク質及びその使用
|
|
JP2025525792A
(ja)
|
2022-07-29 |
2025-08-07 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
トランスフェリン受容体１に対して再標的化されるウイルス粒子
|
|
AU2023312978A1
(en)
|
2022-07-29 |
2025-03-20 |
Regeneron Pharmaceuticals, Inc. |
Anti-tfr:payload fusions and methods of use thereof
|
|
AU2023314808A1
(en)
|
2022-07-29 |
2025-03-20 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for transferrin receptor (tfr)-mediated delivery to the brain and muscle
|
|
US11773160B1
(en)
|
2022-08-05 |
2023-10-03 |
Anaveon AG |
Immune-stimulating IL-2 fusion proteins
|
|
CN119654163A
(zh)
|
2022-08-09 |
2025-03-18 |
魁尔斯弗生物治疗股份有限公司 |
与clec12a结合的抗体
|
|
CA3266599A1
(en)
|
2022-09-07 |
2024-11-07 |
Quantitative Biosciences, Inc. |
UNIQUE VARIABLE DOMAIN ANTIBODIES SPECIFIC TO FENTANYL AND USE IN A CONTINUOUS AGGLUTINATION TEST
|
|
JP2025535871A
(ja)
|
2022-09-26 |
2025-10-30 |
ウォーターストーン ファーマシューティカルズ（ウーハン）カンパニー，リミティド |
Ｆｃ－長鎖脂肪酸鎖を含む超長作用型プラットフォーム
|
|
EP4598958A1
(en)
|
2022-10-05 |
2025-08-13 |
Amgen Inc. |
Combination therapies comprising t-cell redirecting therapies and agonistic anti-il-2r antibodies or fragments thereof
|
|
EP4612184A1
(en)
|
2022-11-04 |
2025-09-10 |
Regeneron Pharmaceuticals, Inc. |
Calcium voltage-gated channel auxiliary subunit gamma 1 (cacng1) binding proteins and cacng1-mediated delivery to skeletal muscle
|
|
WO2024107765A2
(en)
|
2022-11-14 |
2024-05-23 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for fibroblast growth factor receptor 3-mediated delivery to astrocytes
|
|
US20240158515A1
(en)
|
2022-11-14 |
2024-05-16 |
Regeneron Pharmaceuticals, Inc. |
Anti-fgfr3 antibodies and antigen-binding fragments and methods of use thereof
|
|
EP4634227A1
(en)
|
2022-12-13 |
2025-10-22 |
Seagen Inc. |
Site-specific engineered cysteine antibody drug conjugates
|
|
WO2024130158A1
(en)
|
2022-12-16 |
2024-06-20 |
Modernatx, Inc. |
Lipid nanoparticles and polynucleotides encoding extended serum half-life interleukin-22 for the treatment of metabolic disease
|
|
EP4640234A1
(en)
|
2022-12-23 |
2025-10-29 |
Hanmi Pharm. Co., Ltd. |
Pharmaceutical composition for preventing or treating graft-versus-host disease containing glp-2 derivative or long-acting conjugate thereof
|
|
AU2023408268A1
(en)
|
2022-12-23 |
2025-07-10 |
Hanmi Pharm. Co., Ltd. |
Formulations comprising immune stimulating IL-2 analog conjugates
|
|
WO2024150074A2
(en)
|
2023-01-13 |
2024-07-18 |
Takeda Pharmaceutical Company Limited |
Coronavirus antibodies and therapeutic uses thereof
|
|
WO2024178056A1
(en)
|
2023-02-21 |
2024-08-29 |
Teneobio, Inc. |
C-kit binding proteins, chimeric antigen receptors, and uses thereof
|
|
TW202448928A
(zh)
|
2023-03-02 |
2024-12-16 |
美商艾羅伊治療公司 |
抗cd22抗體及其用途
|
|
PE20260036A1
(es)
|
2023-03-07 |
2026-01-09 |
Hanmi Pharmaceutical Co Ltd |
Composicion farmaceutica que comprende analogo de interleucina-2 (il-2) o conjugado del mismo para prevenir o tratar el cancer
|
|
EP4678181A1
(en)
|
2023-03-07 |
2026-01-14 |
Hanmi Pharm. Co., Ltd. |
Combination therapy of interleukin-2 analog or conjugate thereof and immune checkpoint inhibitor for prevention or treatment of cancer
|
|
WO2024194685A2
(en)
|
2023-03-17 |
2024-09-26 |
Oxitope Pharma B.V. |
Anti-phosphocholine antibodies and methods of use thereof
|
|
EP4680632A2
(en)
|
2023-03-17 |
2026-01-21 |
Oxitope Pharma B.V. |
Anti-phosphocholine antibodies and methods of use thereof
|
|
EP4688165A1
(en)
|
2023-03-31 |
2026-02-11 |
ALK-Abelló A/S |
Allergen binding antibodies suitable for treating tree pollen allergies
|
|
CN121152802A
(zh)
|
2023-04-18 |
2025-12-16 |
魁尔斯弗生物治疗股份有限公司 |
与ly6g6d结合的抗体
|
|
WO2025006639A2
(en)
|
2023-06-27 |
2025-01-02 |
Avidity Biosciences, Inc. |
Compositions and methods of using prkag2-targeting antibody-oligonucleotide conjugates abstract
|
|
US12409230B2
(en)
|
2023-06-30 |
2025-09-09 |
Avidity Biosciences, Inc. |
Compositions comprising PLN-targeting anti-transferrin receptor antibody-polynucleotides and methods of use thereof to treat cardiomyopathy
|
|
AR133384A1
(es)
|
2023-07-28 |
2025-09-24 |
Regeneron Pharma |
Anti-tfr:esfingomielinasa ácida para el tratamiento de la deficiencia de esfingomielinasa ácida
|
|
AU2024317483A1
(en)
|
2023-07-28 |
2026-01-29 |
Regeneron Pharmaceuticals, Inc. |
Anti-tfr:gaa and anti-cd63:gaa insertion for treatment of pompe disease
|
|
WO2025037108A2
(en)
|
2023-08-15 |
2025-02-20 |
Board Of Trustees Of The Leland Stanford Junior University |
Modified thrombopoietin
|
|
US20250101101A1
(en)
|
2023-09-01 |
2025-03-27 |
iTeos Belgium SA |
Anti-trem2 antibodies and methods of use
|
|
WO2025054181A1
(en)
|
2023-09-05 |
2025-03-13 |
Seagen Inc. |
Targeted degrader molecules and ligand drug conjugates thereof
|
|
WO2025059215A1
(en)
|
2023-09-12 |
2025-03-20 |
Aadigen, Llc |
Methods and compositions for treating or preventing cancer
|
|
WO2025076389A1
(en)
|
2023-10-06 |
2025-04-10 |
Seagen Inc. |
Methods of treating advanced solid tumors with b7-h4 antibody-drug conjugates
|
|
WO2025090774A1
(en)
|
2023-10-24 |
2025-05-01 |
Seagen Inc. |
Chemotherapeutic compounds and methods of use
|
|
WO2025104604A1
(en)
|
2023-11-14 |
2025-05-22 |
Janssen Pharmaceuticals, Inc. |
Anti-respiratory syncytial virus antibodies and uses thereof
|
|
WO2025128343A1
(en)
|
2023-12-11 |
2025-06-19 |
Just-Evotec Biologics, Inc. |
Protein expression using trans-splicing and split selectable markers
|
|
WO2025133707A1
(en)
|
2023-12-19 |
2025-06-26 |
Vectory Therapeutics B.V. |
Anti-tdp-43 antibodies and uses thereof
|
|
WO2025133694A1
(en)
|
2023-12-20 |
2025-06-26 |
argenx BV |
Fcrn/hsa-binding molecules and methods of use
|
|
WO2025149947A1
(en)
|
2024-01-12 |
2025-07-17 |
Seagen Inc. |
Antibody-drug conjugates
|
|
WO2025155877A2
(en)
|
2024-01-18 |
2025-07-24 |
The Regents Of The University Of California |
Antibodies binding to pad4 and uses thereof
|
|
US12521446B2
(en)
|
2024-02-27 |
2026-01-13 |
Bristol-Myers Squibb Company |
Anti-CEACAM5 antibody drug conjugates
|
|
WO2025184208A1
(en)
|
2024-02-27 |
2025-09-04 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibodies and uses thereof
|
|
US20250276074A1
(en)
|
2024-03-01 |
2025-09-04 |
Prelude Therapeutics Incorporated |
Brm and brg1 targeting antibody-drug conjugates and methods of use thereof
|
|
US20250361297A1
(en)
|
2024-03-12 |
2025-11-27 |
Adaptam Therapeutics, S.L. |
Anti- siglec-15 binding molecules and methods of use
|
|
WO2025217101A2
(en)
|
2024-04-09 |
2025-10-16 |
Amgen Inc. |
Agonistic anti-il-2rbg heavy‑chain antibodies
|
|
TW202544034A
(zh)
|
2024-05-06 |
2025-11-16 |
美商榮都醫療公司 |
結合至ｃｄ２８及ｎｅｃｔｉｎ－４之雙特異性抗體
|
|
WO2026006492A2
(en)
|
2024-06-25 |
2026-01-02 |
Ypsilon Therapeutics, Inc. |
Anti-prame/hla-a2 antibodies and uses thereof
|
|
WO2026006495A1
(en)
|
2024-06-25 |
2026-01-02 |
Alloy Therapeutics, Inc. |
Anti-wt1/hla-a2 antibody and uses thereof
|
|
WO2026006494A1
(en)
|
2024-06-25 |
2026-01-02 |
Alloy Therapeutics, Inc. |
Anti-cd3 antibodies and uses thereof
|