|
US6100387A
(en)
|
1997-02-28 |
2000-08-08 |
Genetics Institute, Inc. |
Chimeric polypeptides containing chemokine domains
|
|
US6852508B1
(en)
|
1997-02-28 |
2005-02-08 |
Genetics Institute, Llc |
Chemokine with amino-terminal modifications
|
|
ES2590912T3
(es)
|
1997-12-08 |
2016-11-24 |
Merck Patent Gmbh |
Proteínas de fusión heterodiméricas útiles para inmunoterapia dirigida y estimulación general del sistema inmunitario
|
|
US6528624B1
(en)
|
1998-04-02 |
2003-03-04 |
Genentech, Inc. |
Polypeptide variants
|
|
EP1105427A2
(en)
*
|
1998-08-17 |
2001-06-13 |
Abgenix, Inc. |
Generation of modified molecules with increased serum half-lives
|
|
MEP42108A
(en)
|
1998-10-23 |
2011-02-10 |
Kiren Amgen Inc |
Dimeric thrombopoietin peptide mimetics binding to mp1 receptor and having thrombopoietic activity
|
|
US7488590B2
(en)
|
1998-10-23 |
2009-02-10 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
|
US6660843B1
(en)
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
|
GB9824632D0
(en)
|
1998-11-10 |
1999-01-06 |
Celltech Therapeutics Ltd |
Biological compounds
|
|
US7183387B1
(en)
|
1999-01-15 |
2007-02-27 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
PL209392B1
(pl)
*
|
1999-01-15 |
2011-08-31 |
Genentech Inc |
Przeciwciało, komórka gospodarza, sposób wytwarzania przeciwciała oraz zastosowanie przeciwciała
|
|
GB9908263D0
(en)
*
|
1999-04-13 |
1999-06-02 |
Binding Site The Limited |
Eliciting improved immune responses
|
|
US7291714B1
(en)
|
1999-06-30 |
2007-11-06 |
Millennium Pharmaceuticals, Inc. |
Glycoprotein VI and uses thereof
|
|
US7067110B1
(en)
|
1999-07-21 |
2006-06-27 |
Emd Lexigen Research Center Corp. |
Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
|
MXPA02001417A
(es)
|
1999-08-09 |
2002-08-12 |
Lexigen Pharm Corp |
Complejos multiples de citosina-anticuerpo.
|
|
US7459540B1
(en)
|
1999-09-07 |
2008-12-02 |
Amgen Inc. |
Fibroblast growth factor-like polypeptides
|
|
CA2391080A1
(en)
|
1999-11-12 |
2001-05-25 |
Merck Patent Gesellschaft Mit Beschraenkter Haftung |
Erythropoietin forms with improved properties
|
|
US6808902B1
(en)
|
1999-11-12 |
2004-10-26 |
Amgen Inc. |
Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
|
|
AU2002219944B2
(en)
|
2000-11-28 |
2008-02-21 |
Medimmune, Llc |
Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
|
|
US7229619B1
(en)
|
2000-11-28 |
2007-06-12 |
Medimmune, Inc. |
Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
|
|
HUP0204475A2
(en)
|
2000-02-11 |
2003-04-28 |
Merck Patent Gmbh |
Enhancing the circulating half-life of antibody-based fusion proteins
|
|
DE60117781T2
(de)
|
2000-04-21 |
2006-11-23 |
Amgen Inc., Thousand Oaks |
Peptidderivate des apolipoproteins-a1/aii
|
|
US6667300B2
(en)
|
2000-04-25 |
2003-12-23 |
Icos Corporation |
Inhibitors of human phosphatidylinositol 3-kinase delta
|
|
US6677136B2
(en)
*
|
2000-05-03 |
2004-01-13 |
Amgen Inc. |
Glucagon antagonists
|
|
WO2001087977A2
(en)
|
2000-05-12 |
2001-11-22 |
Amgen Inc. |
Methods and compositions of matter concerning april/g70, bcma, blys/agp-3, and taci
|
|
KR20030064275A
(ko)
|
2000-06-29 |
2003-07-31 |
메르크 파텐트 게엠베하 |
면역싸이토카인 흡수 증강제와의 조합 치료에 의한항체-싸이토카인 융합 단백질 매개 면역 반응 증강
|
|
US6818216B2
(en)
|
2000-11-28 |
2004-11-16 |
Medimmune, Inc. |
Anti-RSV antibodies
|
|
US7179900B2
(en)
|
2000-11-28 |
2007-02-20 |
Medimmune, Inc. |
Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
|
|
US6855493B2
(en)
|
2000-11-28 |
2005-02-15 |
Medimmune, Inc. |
Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
|
|
US7658921B2
(en)
|
2000-12-12 |
2010-02-09 |
Medimmune, Llc |
Molecules with extended half-lives, compositions and uses thereof
|
|
AU2008201419C1
(en)
*
|
2000-12-12 |
2018-01-18 |
Board Of Regents, The University Of Texas System |
Molecules with extended half-lives, compositions and uses thereof
|
|
US7083784B2
(en)
*
|
2000-12-12 |
2006-08-01 |
Medimmune, Inc. |
Molecules with extended half-lives, compositions and uses thereof
|
|
AU2011253690C1
(en)
*
|
2000-12-12 |
2018-01-18 |
Board Of Regents, The University Of Texas System |
Molecules with extended half-lives, compositions and uses thereof
|
|
RU2003129528A
(ru)
|
2001-03-07 |
2005-04-10 |
Мерк Патент ГмбХ (DE) |
Способ экспрессии белков, содержащих в качестве компонента гибридный изотип антитела
|
|
WO2002079415A2
(en)
|
2001-03-30 |
2002-10-10 |
Lexigen Pharmaceuticals Corp. |
Reducing the immunogenicity of fusion proteins
|
|
US7256257B2
(en)
|
2001-04-30 |
2007-08-14 |
Seattle Genetics, Inc. |
Pentapeptide compounds and uses related thereto
|
|
EP1383785B1
(en)
|
2001-05-03 |
2011-03-16 |
Merck Patent GmbH |
Recombinant tumor specific antibody and use thereof
|
|
DK1385882T3
(da)
|
2001-05-11 |
2008-02-11 |
Amgen Inc |
Peptider og relaterede molekyler, der binder til TALL-1
|
|
US7332474B2
(en)
|
2001-10-11 |
2008-02-19 |
Amgen Inc. |
Peptides and related compounds having thrombopoietic activity
|
|
US7138370B2
(en)
|
2001-10-11 |
2006-11-21 |
Amgen Inc. |
Specific binding agents of human angiopoietin-2
|
|
DK1454138T3
(da)
|
2001-12-04 |
2012-02-13 |
Merck Patent Gmbh |
Immunocytokiner med moduleret selektivitet
|
|
US8188231B2
(en)
|
2002-09-27 |
2012-05-29 |
Xencor, Inc. |
Optimized FC variants
|
|
US7662925B2
(en)
|
2002-03-01 |
2010-02-16 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
|
ATE525398T1
(de)
|
2002-05-10 |
2011-10-15 |
Medimmune Inc |
Epha2 monoklonale antikörper und deren anwendungsverfahren
|
|
US7425618B2
(en)
|
2002-06-14 |
2008-09-16 |
Medimmune, Inc. |
Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
|
|
US7132100B2
(en)
|
2002-06-14 |
2006-11-07 |
Medimmune, Inc. |
Stabilized liquid anti-RSV antibody formulations
|
|
DK1545613T3
(da)
|
2002-07-31 |
2011-11-14 |
Seattle Genetics Inc |
Auristatinkonjugater og deres anvendelse til behandling af cancer, en autoimmun sygdom eller en infektiøs sygdom
|
|
US8946387B2
(en)
|
2002-08-14 |
2015-02-03 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US8968730B2
(en)
|
2002-08-14 |
2015-03-03 |
Macrogenics Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US8530627B2
(en)
|
2002-08-14 |
2013-09-10 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US8187593B2
(en)
|
2002-08-14 |
2012-05-29 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
JP2006508056A
(ja)
|
2002-08-28 |
2006-03-09 |
イミュネックス・コーポレーション |
心臓血管疾患を治療するための組成物および方法
|
|
US6919426B2
(en)
|
2002-09-19 |
2005-07-19 |
Amgen Inc. |
Peptides and related molecules that modulate nerve growth factor activity
|
|
US7361740B2
(en)
|
2002-10-15 |
2008-04-22 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
US7217797B2
(en)
|
2002-10-15 |
2007-05-15 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
US7365168B2
(en)
|
2002-10-15 |
2008-04-29 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
WO2004055056A1
(en)
|
2002-12-17 |
2004-07-01 |
Merck Patent Gmbh |
Humanized antibody (h14.18) of the mouse 14.18 antibody binding to gd2 and its fusion with il-2
|
|
CA2512729C
(en)
|
2003-01-09 |
2014-09-16 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant fc regions and methods of using same
|
|
US7960512B2
(en)
|
2003-01-09 |
2011-06-14 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant Fc regions and methods of using same
|
|
US8388955B2
(en)
|
2003-03-03 |
2013-03-05 |
Xencor, Inc. |
Fc variants
|
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
|
US8084582B2
(en)
|
2003-03-03 |
2011-12-27 |
Xencor, Inc. |
Optimized anti-CD20 monoclonal antibodies having Fc variants
|
|
JP4685764B2
(ja)
*
|
2003-04-10 |
2011-05-18 |
アボット バイオセラピューティクス コーポレイション |
変異誘発による抗体のＦｃＲｎ結合親和力又は血清半減期の改変
|
|
AU2004229501B2
(en)
|
2003-04-11 |
2011-08-18 |
Medimmune, Llc |
Recombinant IL-9 antibodies and uses thereof
|
|
US9051373B2
(en)
|
2003-05-02 |
2015-06-09 |
Xencor, Inc. |
Optimized Fc variants
|
|
PL2298347T3
(pl)
|
2003-05-06 |
2016-03-31 |
Bioverativ Therapeutics Inc |
Białka chimeryczne czynnika krzepnięcia do leczenia zaburzenia hemostazy
|
|
EP2133362B1
(en)
|
2003-07-25 |
2012-04-18 |
Amgen, Inc |
Methods relating to LDCAM and CRTAM
|
|
AU2004266159A1
(en)
|
2003-08-22 |
2005-03-03 |
Biogen Idec Ma Inc. |
Improved antibodies having altered effector function and methods for making the same
|
|
US8101720B2
(en)
|
2004-10-21 |
2012-01-24 |
Xencor, Inc. |
Immunoglobulin insertions, deletions and substitutions
|
|
US9714282B2
(en)
|
2003-09-26 |
2017-07-25 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
|
WO2005037867A1
(en)
|
2003-10-15 |
2005-04-28 |
Pdl Biopharma, Inc. |
ALTERATION OF Fc-FUSION PROTEIN SERUM HALF-LIVES BY MUTAGENESIS OF POSITIONS 250, 314 AND/OR 428 OF THE HEAVY CHAIN CONSTANT REGION OF IG
|
|
AU2004287431B2
(en)
|
2003-10-27 |
2010-03-11 |
Amgen Inc. |
Compositions and methods to modulate an immune response to an immunogenic therapeutic agent
|
|
EP2478912B1
(en)
|
2003-11-06 |
2016-08-31 |
Seattle Genetics, Inc. |
Auristatin conjugates with anti-HER2 or anti-CD22 antibodies and their use in therapy
|
|
ES2383300T3
(es)
|
2003-11-13 |
2012-06-20 |
Hanmi Holdings Co., Ltd |
Fragmento Fc de IgG para un vehículo de fármacos y procedimiento para su preparación
|
|
KR101135244B1
(ko)
|
2007-11-29 |
2012-04-24 |
한미사이언스 주식회사 |
인슐린 분비 펩타이드 결합체를 포함하는 비만 관련질환 치료용 조성물
|
|
US7371381B2
(en)
|
2003-12-12 |
2008-05-13 |
Amgen Inc. |
Anti-galanin antibodies and uses thereof
|
|
ES2305886T3
(es)
|
2003-12-30 |
2008-11-01 |
Merck Patent Gmbh |
Proteinas de fusion de il-7 con porciones de anticuerpo, su preparacion y su empleo.
|
|
RU2370276C2
(ru)
|
2003-12-31 |
2009-10-20 |
Мерк Патент Гмбх |
Fc-ЭРИТРОПОЭТИН СЛИТЫЙ БЕЛОК С УЛУЧШЕННОЙ ФАРМАКОКИНЕТИКОЙ
|
|
SI2311873T1
(sl)
|
2004-01-07 |
2018-12-31 |
Novartis Vaccines And Diagnostics, Inc. |
M-CSF-specifična monoklonska protitelesa in njihova uporaba
|
|
AU2005206277B2
(en)
|
2004-01-22 |
2011-06-23 |
Merck Patent Gmbh |
Anti-cancer antibodies with reduced complement fixation
|
|
BRPI0507174A
(pt)
|
2004-01-28 |
2008-04-01 |
Syntonix Pharmaceuticals Inc |
proteìnas de fusão hormÈnio-fc (fsh-fc) heterodiméricas estimuladoras de folìculo para o tratamento da infertilidade
|
|
EP1737890A2
(en)
|
2004-03-24 |
2007-01-03 |
Xencor, Inc. |
Immunoglobulin variants outside the fc region
|
|
CA2565874C
(en)
|
2004-05-10 |
2017-10-03 |
Macrogenics, Inc. |
Humanized fc.gamma.riib-specific antibodies and methods of use thereof
|
|
WO2005113556A1
(en)
|
2004-05-13 |
2005-12-01 |
Icos Corporation |
Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
|
|
US7632924B2
(en)
|
2004-06-18 |
2009-12-15 |
Ambrx, Inc. |
Antigen-binding polypeptides and their uses
|
|
US8143380B2
(en)
|
2004-07-08 |
2012-03-27 |
Amgen Inc. |
Therapeutic peptides
|
|
US20150010550A1
(en)
|
2004-07-15 |
2015-01-08 |
Xencor, Inc. |
OPTIMIZED Fc VARIANTS
|
|
AU2005287406B2
(en)
|
2004-07-26 |
2011-08-18 |
Biogen Ma Inc. |
Anti-CD154 antibodies
|
|
AU2005274905B2
(en)
|
2004-08-04 |
2010-12-23 |
Mentrik Biotech, Llc |
Variant Fc regions
|
|
EP1793850A4
(en)
|
2004-09-21 |
2010-06-30 |
Medimmune Inc |
ANTIBODIES TO THE METHOD AND METHOD FOR THE PRODUCTION OF VACCINES AGAINST THE RESPIRATORY SYNCYTIAL VIRUS
|
|
WO2006036834A2
(en)
|
2004-09-24 |
2006-04-06 |
Amgen Inc. |
MODIFIED Fc MOLECULES
|
|
CA2585717A1
(en)
|
2004-10-27 |
2006-05-04 |
Medimmune Inc. |
Modulation of antibody specificity by tailoring the affinity to cognate antigens
|
|
AU2005335714B2
(en)
|
2004-11-10 |
2012-07-26 |
Macrogenics, Inc. |
Engineering Fc antibody regions to confer effector function
|
|
US8367805B2
(en)
|
2004-11-12 |
2013-02-05 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US8546543B2
(en)
|
2004-11-12 |
2013-10-01 |
Xencor, Inc. |
Fc variants that extend antibody half-life
|
|
AU2005304624B2
(en)
|
2004-11-12 |
2010-10-07 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US8288352B2
(en)
|
2004-11-12 |
2012-10-16 |
Seattle Genetics, Inc. |
Auristatins having an aminobenzoic acid unit at the N terminus
|
|
RU2437893C2
(ru)
|
2004-12-09 |
2011-12-27 |
Мерк Патент Гмбх |
Варианты il-7 со сниженной иммуногенностью
|
|
EP1699826B1
(en)
|
2005-01-05 |
2009-03-11 |
f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. |
Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions
|
|
KR100754667B1
(ko)
|
2005-04-08 |
2007-09-03 |
한미약품 주식회사 |
비펩타이드성 중합체로 개질된 면역글로불린 Ｆｃ 단편 및이를 포함하는 약제학적 조성물
|
|
ES2971647T3
(es)
|
2005-04-15 |
2024-06-06 |
Macrogenics Inc |
Diacuerpos covalentes y usos de los mismos
|
|
US9963510B2
(en)
|
2005-04-15 |
2018-05-08 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
US9284375B2
(en)
|
2005-04-15 |
2016-03-15 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
US11254748B2
(en)
|
2005-04-15 |
2022-02-22 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
US7833979B2
(en)
|
2005-04-22 |
2010-11-16 |
Amgen Inc. |
Toxin peptide therapeutic agents
|
|
KR101443050B1
(ko)
|
2005-05-06 |
2014-09-22 |
지모제넥틱스, 인코포레이티드 |
Ｉｌ-31 단클론성 항체 및 사용법
|
|
HUE029021T2
(en)
|
2005-06-21 |
2017-02-28 |
Xoma (Us) Llc |
IL-1beta-binding antibodies and fragments thereof
|
|
KR20080025174A
(ko)
|
2005-06-23 |
2008-03-19 |
메디뮨 인코포레이티드 |
응집 및 단편화 프로파일이 최적화된 항체 제제
|
|
ES2708763T3
(es)
|
2005-07-07 |
2019-04-11 |
Seattle Genetics Inc |
Compuestos de monometilvalina que tienen modificaciones de la cadena lateral de fenilalanina en el extremo C
|
|
WO2007008943A2
(en)
|
2005-07-08 |
2007-01-18 |
Xencor, Inc. |
Optimized anti-ep-cam antibodies
|
|
DK3248613T3
(da)
|
2005-07-18 |
2022-03-14 |
Seagen Inc |
Beta-glucuronid-lægemiddel-linkerkonjugater
|
|
JP5457671B2
(ja)
|
2005-07-28 |
2014-04-02 |
ノバルティス アーゲー |
Ｍ−ｃｓｆ特異的モノクローナル抗体およびその使用
|
|
PL2573114T3
(pl)
|
2005-08-10 |
2016-10-31 |
|
Identyfikacja i inżynieria przeciwciał z wariantami regionów FC oraz sposoby ich stosowania
|
|
US8008453B2
(en)
|
2005-08-12 |
2011-08-30 |
Amgen Inc. |
Modified Fc molecules
|
|
WO2007041635A2
(en)
|
2005-10-03 |
2007-04-12 |
Xencor, Inc. |
Fc variants with optimized fc receptor binding properties
|
|
WO2007044616A2
(en)
|
2005-10-06 |
2007-04-19 |
Xencor, Inc. |
Optimized anti-cd30 antibodies
|
|
WO2007142667A2
(en)
|
2005-10-13 |
2007-12-13 |
Human Genome Sciences, Inc. |
Treatment of patients with autoantibody positive disease
|
|
TW200732350A
(en)
|
2005-10-21 |
2007-09-01 |
Amgen Inc |
Methods for generating monovalent IgG
|
|
WO2007111714A2
(en)
|
2005-11-28 |
2007-10-04 |
Zymogenetics, Inc. |
Il-21 antagonists
|
|
AU2006326867A1
(en)
|
2005-12-20 |
2007-06-28 |
Cephalon Australia Pty Ltd |
Chimeric antibodies with part New World primate binding regions
|
|
WO2007102946A2
(en)
|
2006-01-23 |
2007-09-13 |
Amgen Inc. |
Crystalline polypeptides
|
|
US7846439B2
(en)
|
2006-02-01 |
2010-12-07 |
Cephalon Australia Pty Ltd |
Domain antibody construct
|
|
JP2009529915A
(ja)
|
2006-03-20 |
2009-08-27 |
ゾーマ テクノロジー リミテッド |
ガストリン物質に対して特異的なヒト抗体および方法
|
|
CN104761637B
(zh)
|
2006-03-31 |
2021-10-15 |
中外制药株式会社 |
调控抗体血液动力学的方法
|
|
US9283260B2
(en)
|
2006-04-21 |
2016-03-15 |
Amgen Inc. |
Lyophilized therapeutic peptibody formulations
|
|
TWI395754B
(zh)
|
2006-04-24 |
2013-05-11 |
Amgen Inc |
人類化之ｃ-ｋｉｔ抗體
|
|
CA2650730A1
(en)
|
2006-04-27 |
2007-11-08 |
Pikamab, Inc. |
Methods and compositions for antibody therapy
|
|
WO2008105886A2
(en)
|
2006-05-26 |
2008-09-04 |
Macrogenics, Inc. |
HUMANIZED FCγRIIB-SPECIFIC ANTIBODIES AND METHODS OF USE THEREOF
|
|
SG177907A1
(en)
|
2006-06-14 |
2012-02-28 |
Macrogenics Inc |
Methods for the treatment of autoimmune disorders using immunosuppressive monoclonal antibodies with reduced toxicity
|
|
US7981425B2
(en)
|
2006-06-19 |
2011-07-19 |
Amgen Inc. |
Thrombopoietic compounds
|
|
EP2035452B1
(en)
|
2006-06-22 |
2012-04-25 |
Novo Nordisk A/S |
Soluble heterodimeric receptors and uses thereof
|
|
WO2008002933A2
(en)
|
2006-06-26 |
2008-01-03 |
Macrogenics, Inc. |
Combination of fcgammariib antibodies and cd20-specific antibodies and methods of use thereof
|
|
US20080096900A1
(en)
|
2006-06-26 |
2008-04-24 |
Amgen Inc. |
Methods for treating atherosclerosis
|
|
ES2599319T3
(es)
|
2006-06-26 |
2017-02-01 |
Macrogenics, Inc. |
Anticuerpos específicos de Fc RIIB y métodos de uso de éstos
|
|
AT503889B1
(de)
|
2006-07-05 |
2011-12-15 |
Star Biotechnologische Forschungs Und Entwicklungsges M B H F |
Multivalente immunglobuline
|
|
AT503902B1
(de)
|
2006-07-05 |
2008-06-15 |
F Star Biotech Forsch & Entw |
Verfahren zur manipulation von immunglobulinen
|
|
AT503861B1
(de)
|
2006-07-05 |
2008-06-15 |
F Star Biotech Forsch & Entw |
Verfahren zur manipulation von t-zell-rezeptoren
|
|
CL2007002225A1
(es)
|
2006-08-03 |
2008-04-18 |
Astrazeneca Ab |
Agente de union especifico para un receptor del factor de crecimiento derivado de plaquetas (pdgfr-alfa); molecula de acido nucleico que lo codifica; vector y celula huesped que la comprenden; conjugado que comprende al agente; y uso del agente de un
|
|
EP2064244B1
(en)
|
2006-08-03 |
2019-06-05 |
MedImmune Limited |
ANTIBODIES DIRECTED TO alphaVbeta6 AND USES THEREOF
|
|
CA2659820A1
(en)
|
2006-08-04 |
2008-02-14 |
Novartis Ag |
Ephb3-specific antibody and uses thereof
|
|
US8350011B2
(en)
|
2006-08-04 |
2013-01-08 |
Medimmune Limited |
Antibodies to ErbB2
|
|
PL2383297T3
(pl)
|
2006-08-14 |
2013-06-28 |
Xencor Inc |
Zoptymalizowane przeciwciała ukierunkowane na CD19
|
|
AR064801A1
(es)
|
2006-08-18 |
2009-04-29 |
Xoma Technology Ltd |
Anticuerpo especifico prlr (receptor de prolactina) y sus usos
|
|
AU2007290570C1
(en)
|
2006-08-28 |
2013-08-15 |
Kyowa Kirin Co., Ltd. |
Antagonistic human LIGHT-specific human monoclonal antibodies
|
|
ES2548714T3
(es)
|
2006-09-01 |
2015-10-20 |
Zymogenetics, Inc. |
Anticuerpos monoclonales IL-31 y procedimientos de uso
|
|
WO2008036688A2
(en)
|
2006-09-18 |
2008-03-27 |
Xencor, Inc. |
Optimized antibodies that target hm1.24
|
|
AU2007313300A1
(en)
|
2006-10-16 |
2008-04-24 |
Medimmune, Llc. |
Molecules with reduced half-lives, compositions and uses thereof
|
|
PE20081140A1
(es)
|
2006-10-25 |
2008-09-22 |
Amgen Inc |
Agentes terapeuticos a base de peptidos derivados de toxinas
|
|
HU0700534D0
(en)
|
2006-11-24 |
2007-10-29 |
Mezoegazdasagi Biotechnologiai |
Transgenic animal with enhanced immune response and method for the preparation thereof
|
|
PT2099823E
(pt)
|
2006-12-01 |
2014-12-22 |
Seattle Genetics Inc |
Agentes de ligação ao alvo variantes e suas utilizações
|
|
WO2008070780A1
(en)
|
2006-12-07 |
2008-06-12 |
Novartis Ag |
Antagonist antibodies against ephb3
|
|
US8652466B2
(en)
|
2006-12-08 |
2014-02-18 |
Macrogenics, Inc. |
Methods for the treatment of disease using immunoglobulins having Fc regions with altered affinities for FcγRactivating and FcγRinhibiting
|
|
EP3124045A3
(en)
|
2006-12-20 |
2017-05-03 |
Xoma (Us) Llc |
Treatment of il-1 beta related diseases
|
|
JP2008169195A
(ja)
|
2007-01-05 |
2008-07-24 |
Hanmi Pharmaceutical Co Ltd |
キャリア物質を用いたインスリン分泌ペプチド薬物結合体
|
|
CA2682292A1
(en)
|
2007-03-30 |
2008-10-09 |
Medimmune, Llc |
Aqueous formulation comprising an anti-human interferon alpha antibody
|
|
AU2008246442B2
(en)
|
2007-05-04 |
2014-07-03 |
Technophage, Investigacao E Desenvolvimento Em Biotecnologia, Sa |
Engineered rabbit antibody variable domains and uses thereof
|
|
CN101743249B
(zh)
|
2007-05-11 |
2017-08-08 |
阿尔托生物科学有限公司 |
融合分子与il‑15变异体
|
|
MX376656B
(es)
|
2007-05-14 |
2025-03-07 |
Kyowa Kirin Co Ltd |
Metodos para reducir niveles de basófilos.
|
|
EP2162540A2
(en)
|
2007-05-22 |
2010-03-17 |
Amgen Inc. |
Compositions and methods for producing bioactive fusion proteins
|
|
EP2176298B1
(en)
|
2007-05-30 |
2017-11-15 |
Xencor, Inc. |
Methods and compositions for inhibiting cd32b expressing cells
|
|
EP1997830A1
(en)
|
2007-06-01 |
2008-12-03 |
AIMM Therapeutics B.V. |
RSV specific binding molecules and means for producing them
|
|
ES2627223T3
(es)
|
2007-06-26 |
2017-07-27 |
F-Star Biotechnologische Forschungs- Und Entwicklungsges.M.B.H |
Presentación de agentes de unión
|
|
WO2009014708A2
(en)
|
2007-07-23 |
2009-01-29 |
Cell Genesys, Inc. |
Pd-1 antibodies in combination with a cytokine-secreting cell and methods of use thereof
|
|
HRP20140315T1
(hr)
|
2007-07-26 |
2014-05-09 |
Amgen Inc. |
Modificirani enzimi lecitin-kolesterol aciltransferaze
|
|
KR20100058509A
(ko)
|
2007-07-31 |
2010-06-03 |
메디뮨 엘엘씨 |
다중특이적 에피토프 결합 단백질 및 이의 용도
|
|
PE20140196A1
(es)
|
2007-08-09 |
2014-03-19 |
Boehringer Ingelheim Int |
Anticuerpos anti-cd37
|
|
MX338397B
(es)
|
2007-08-29 |
2016-04-15 |
Sanofi Aventis |
Anticuerpos anti - cxcr5 humanizados, derivados de los mismos y su uso.
|
|
EP2535349A1
(en)
|
2007-09-26 |
2012-12-19 |
UCB Pharma S.A. |
Dual specificity antibody fusions
|
|
ES2595638T3
(es)
|
2007-09-26 |
2017-01-02 |
Chugai Seiyaku Kabushiki Kaisha |
Método para modificar el punto isoeléctrico de un anticuerpo mediante la sustitución de aminoácidos en una CDR
|
|
EP2050764A1
(en)
|
2007-10-15 |
2009-04-22 |
sanofi-aventis |
Novel polyvalent bispecific antibody format and uses thereof
|
|
US7883700B2
(en)
|
2007-12-07 |
2011-02-08 |
Zymogenetics, Inc. |
Anti-human IL-21 monoclonal antibodies
|
|
ME03057B
(me)
|
2007-12-07 |
2019-01-20 |
Zymogenetics Inc |
Molekuli humanizovanih antitela specifični za il-31
|
|
US8795667B2
(en)
|
2007-12-19 |
2014-08-05 |
Macrogenics, Inc. |
Compositions for the prevention and treatment of smallpox
|
|
SI2391650T1
(sl)
|
2007-12-20 |
2015-03-31 |
Xoma (Us) Llc |
Postopki za zdravljenje protina
|
|
EP2235058A2
(en)
|
2007-12-21 |
2010-10-06 |
Amgen, Inc |
Anti-amyloid antibodies and uses thereof
|
|
HRP20150279T1
(hr)
|
2007-12-26 |
2015-05-08 |
Xencor, Inc. |
Fc inaäśice s promijenjenim vezanjem na fcrn
|
|
BRPI0907046A2
(pt)
|
2008-01-18 |
2015-07-28 |
Medimmune Llc |
Anticorpo de cisteína engenheirada, ácido nucleico isolado, vetor, célula hospedeira, conjugado de anticorpo, composição farmacêutica, métodos de detecção de câncer, doenças ou distúrbios autoimunes, inflamatórios ou infecciosos em um indivíduo e de inibição de proliferação de uma célula alvo
|
|
US12492253B1
(en)
|
2008-02-25 |
2025-12-09 |
Xencor, Inc. |
Anti-human C5 antibodies
|
|
DK2265283T3
(da)
|
2008-03-18 |
2014-10-20 |
Seattle Genetics Inc |
Auristatin-lægemiddel-linker-konjugater
|
|
ES2589912T3
(es)
|
2008-04-02 |
2016-11-17 |
Macrogenics, Inc. |
Anticuerpos específicos para el complejo BCR y procedimientos de uso de los mismos
|
|
WO2009123894A2
(en)
|
2008-04-02 |
2009-10-08 |
Macrogenics, Inc. |
Her2/neu-specific antibodies and methods of using same
|
|
KR102057826B1
(ko)
|
2008-04-11 |
2019-12-20 |
추가이 세이야쿠 가부시키가이샤 |
복수 분자의 항원에 반복 결합하는 항원 결합 분자
|
|
WO2009131702A2
(en)
*
|
2008-04-25 |
2009-10-29 |
Dyax Corp. |
Antibodies against fcrn and use thereof
|
|
EP2113255A1
(en)
|
2008-05-02 |
2009-11-04 |
f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. |
Cytotoxic immunoglobulin
|
|
US8034770B2
(en)
|
2008-06-04 |
2011-10-11 |
Amgen Inc. |
FGF21 polypeptides comprising two or more mutations
|
|
EP2307456B1
(en)
|
2008-06-27 |
2014-10-15 |
Amgen Inc. |
Ang-2 inhibition to treat multiple sclerosis
|
|
PY09026846A
(es)
|
2008-08-05 |
2015-09-01 |
Novartis Ag |
Composiciones y métodos para anticuerpos que se dirigen a la proteína de complemento c5
|
|
NZ591488A
(en)
|
2008-09-07 |
2012-11-30 |
Glyconex Inc |
Anti-extended type i glycosphingolipid antibody, derivatives thereof and use
|
|
AU2009294415B2
(en)
|
2008-09-19 |
2015-09-24 |
Medimmune Llc |
Antibodies directed to DLL4 and uses thereof
|
|
JP5913980B2
(ja)
*
|
2008-10-14 |
2016-05-11 |
ジェネンテック， インコーポレイテッド |
免疫グロブリン変異体及びその用途
|
|
JP5933975B2
(ja)
|
2008-11-12 |
2016-06-15 |
メディミューン，エルエルシー |
抗体製剤
|
|
US9492449B2
(en)
|
2008-11-13 |
2016-11-15 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
|
KR20160091440A
(ko)
|
2008-11-13 |
2016-08-02 |
길리아드 칼리스토가 엘엘씨 |
혈액 종양에 대한 요법
|
|
WO2010068722A1
(en)
|
2008-12-12 |
2010-06-17 |
Medimmune, Llc |
Crystals and structure of a human igg fc variant with enhanced fcrn binding
|
|
CA2748158A1
(en)
|
2008-12-23 |
2010-07-01 |
Astrazeneca Ab |
Targeted binding agents directed to .alpha.5.beta.1 and uses thereof
|
|
US8852608B2
(en)
|
2009-02-02 |
2014-10-07 |
Medimmune, Llc |
Antibodies against and methods for producing vaccines for respiratory syncytial virus
|
|
CA2755336C
(en)
|
2009-03-20 |
2015-07-14 |
Amgen Inc. |
Carrier immunoglobulins and uses thereof
|
|
BRPI1012333A2
(pt)
|
2009-03-24 |
2016-03-29 |
Gilead Calistoga Llc |
atropisômeros de derivados de 2-purinil-3-tolil-quinazolinonas e métodos de uso
|
|
DK2421898T3
(en)
|
2009-04-20 |
2016-05-30 |
Oxford Biotherapeutics Ltd |
Cadherin-17 SPECIFIC ANTIBODIES
|
|
AP2011005956A0
(en)
|
2009-04-20 |
2011-10-31 |
Gilead Calistoga Llc |
Methods of treatment for solid tumors.
|
|
SG175233A1
(en)
|
2009-04-22 |
2011-11-28 |
Merck Patent Gmbh |
Antibody fusion proteins with modified fcrn binding sites
|
|
WO2010129600A2
(en)
|
2009-05-05 |
2010-11-11 |
Amgen Inc. |
Fgf21 mutants and uses thereof
|
|
WO2010129503A1
(en)
|
2009-05-05 |
2010-11-11 |
Amgen Inc. |
Fgf21 mutants and uses thereof
|
|
EP2437767B1
(en)
|
2009-06-01 |
2015-07-08 |
MedImmune, LLC |
Molecules with extended half-lives and uses thereof
|
|
CN102482324B
(zh)
|
2009-06-15 |
2014-07-02 |
拜欧肯疗法有限公司 |
能够抑制自身免疫、炎症和癌症进程的新型趋化因子结合多肽
|
|
WO2010148413A2
(en)
|
2009-06-19 |
2010-12-23 |
Medimmune, Llc |
Protease variants
|
|
EP2711018A1
(en)
|
2009-06-22 |
2014-03-26 |
MedImmune, LLC |
Engineered Fc regions for site-specific conjugation
|
|
CA2768843A1
(en)
|
2009-07-21 |
2011-01-27 |
Gilead Calistoga Llc |
Treatment of liver disorders with pi3k inhibitors
|
|
JP5762408B2
(ja)
|
2009-08-13 |
2015-08-12 |
クルセル ホランド ベー ヴェー |
ヒト呼吸器合胞体ウイルス（ｒｓｖ）に対する抗体および使用方法
|
|
CA2769822C
(en)
|
2009-08-13 |
2019-02-19 |
The Johns Hopkins University |
Methods of modulating immune function
|
|
WO2011028952A1
(en)
|
2009-09-02 |
2011-03-10 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
WO2011035205A2
(en)
|
2009-09-18 |
2011-03-24 |
Calmune Corporation |
Antibodies against candida, collections thereof and methods of use
|
|
US8926976B2
(en)
|
2009-09-25 |
2015-01-06 |
Xoma Technology Ltd. |
Modulators
|
|
EP2480888B1
(en)
|
2009-09-25 |
2016-11-30 |
XOMA Technology Ltd. |
Screening methods
|
|
GB201005063D0
(en)
|
2010-03-25 |
2010-05-12 |
Ucb Pharma Sa |
Biological products
|
|
US8568726B2
(en)
|
2009-10-06 |
2013-10-29 |
Medimmune Limited |
RSV specific binding molecule
|
|
JP5898082B2
(ja)
|
2009-10-07 |
2016-04-06 |
マクロジェニクス，インコーポレーテッド |
フコシル化程度の変更により改良されたエフェクター機能を示すＦｃ領域含有ポリペプチドおよびその使用法
|
|
EP2470569A1
(en)
|
2009-10-13 |
2012-07-04 |
Oxford Biotherapeutics Ltd. |
Antibodies against epha10
|
|
WO2011056073A2
(en)
|
2009-11-04 |
2011-05-12 |
Erasmus University Medical Center Rotterdam |
Novel compounds for modulating neovascularisation and methods of treatment using these compounds
|
|
US20120231006A1
(en)
|
2009-11-20 |
2012-09-13 |
Amgen Inc. |
Anti-orai1 antigen binding proteins and uses thereof
|
|
PL2504364T3
(pl)
|
2009-11-24 |
2017-12-29 |
Medimmune Limited |
Ukierunkowane środki wiążące przeciwko B7-H1
|
|
UA109888C2
(uk)
|
2009-12-07 |
2015-10-26 |
|
ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
|
|
KR101312829B1
(ko)
|
2009-12-30 |
2013-09-27 |
한화엘앤씨 주식회사 |
ＨＯ-1 유전자 및 ＴＮＦＲ1-Ｆｃ 유전자를 동시에 발현하는 형질전환 돼지 및 그의 제조 방법
|
|
WO2011091078A2
(en)
|
2010-01-19 |
2011-07-28 |
Xencor, Inc. |
Antibody fc variants with enhanced complement activity
|
|
EP2542256B1
(en)
|
2010-03-04 |
2019-05-22 |
MacroGenics, Inc. |
Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
|
|
PH12012501751A1
(en)
|
2010-03-04 |
2012-11-12 |
Macrogenics Inc |
Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
|
|
AR081066A1
(es)
|
2010-04-02 |
2012-06-06 |
Hanmi Holdings Co Ltd |
Conjugado de insulina donde se usa un fragmento de inmunoglobulina
|
|
AR081755A1
(es)
|
2010-04-02 |
2012-10-17 |
Hanmi Holdings Co Ltd |
Formulacion de accion prolongada de la hormona estimuladora de los foliculos donde se usa un fragmento de inmunoglobulina, metodo de preparacion y metodo para tratar a un sujeto que sufre un trastorno reproductivo
|
|
AR080993A1
(es)
|
2010-04-02 |
2012-05-30 |
Hanmi Holdings Co Ltd |
Formulacion de accion prolongada de interferon beta donde se usa un fragmento de inmunoglobulina
|
|
US20130101590A1
(en)
|
2010-04-09 |
2013-04-25 |
Heather A. Arnett |
Btnl9 proteins, nucleic acids, and antibodies and uses thereof
|
|
CA2796055A1
(en)
|
2010-04-15 |
2011-10-20 |
Amgen Inc. |
Human fgf receptor and .beta.-klotho binding proteins
|
|
PH12012502193A1
(en)
|
2010-05-06 |
2021-08-09 |
Novartis Ag |
Compositions and methods of use for therapeutic low density lipoprotein - related protein 6 (lrp6) multivalent antibodies
|
|
EP2566892B1
(en)
|
2010-05-06 |
2017-12-20 |
Novartis AG |
Compositions and methods of use for therapeutic low density lipoprotein-related protein 6 (lrp6) antibodies
|
|
JP5956982B2
(ja)
|
2010-05-27 |
2016-07-27 |
メルク・シャープ・エンド・ドーム・コーポレイション |
改善された特性を有する抗体の製造方法
|
|
BR112012031638B1
(pt)
|
2010-07-09 |
2021-01-12 |
Janssen Vaccines & Prevention B.V. |
anticorpo anti-rsv ou fragmento de ligação de antígeno do mesmo, anticorpo multivalente, composição farmacêutica, uso de anticorpo ou fragmento de ligação de antígeno, método de detectar infecção por rsv, e, ácido nucleico isolado
|
|
PL3552619T3
(pl)
|
2010-07-09 |
2025-12-01 |
Bioverativ Therapeutics Inc. |
Polipeptydy czynnika ix i sposoby ich zastosowania
|
|
KR101382593B1
(ko)
|
2010-07-21 |
2014-04-10 |
한미사이언스 주식회사 |
신규한 지속형 글루카곤 결합체 및 이를 포함하는 비만 예방 및 치료용 약학적 조성물
|
|
AU2011286024B2
(en)
|
2010-08-02 |
2014-08-07 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
WO2012019061A2
(en)
|
2010-08-05 |
2012-02-09 |
Stem Centrx, Inc. |
Novel effectors and methods of use
|
|
AU2011290672B2
(en)
|
2010-08-20 |
2015-07-09 |
Novartis Ag |
Antibodies for epidermal growth factor receptor 3 (HER3)
|
|
SG10201506782XA
(en)
|
2010-08-27 |
2015-10-29 |
Stem Centrx Inc |
Notum protein modulators and methods of use
|
|
AU2011295715B9
(en)
|
2010-09-03 |
2017-02-23 |
Abbvie Stemcentrx Llc |
Novel modulators and methods of use
|
|
US8507222B2
(en)
|
2010-09-21 |
2013-08-13 |
Altor Bioscience Corporation |
Multimeric IL-15 soluble fusion molecules and methods of making and using same
|
|
US11053299B2
(en)
|
2010-09-21 |
2021-07-06 |
Immunity Bio, Inc. |
Superkine
|
|
MX360946B
(es)
|
2010-09-22 |
2018-10-29 |
Amgen Inc Star |
Inmunoglobulinas portadoras y usos de las mismas.
|
|
UA112062C2
(uk)
|
2010-10-04 |
2016-07-25 |
Бьорінгер Інгельхайм Інтернаціональ Гмбх |
Cd33-зв'язувальний агент
|
|
ES2758994T3
(es)
|
2010-11-05 |
2020-05-07 |
Zymeworks Inc |
Diseño anticuerpo heterodimérico estable con mutaciones en el dominio Fc
|
|
US9023791B2
(en)
|
2010-11-19 |
2015-05-05 |
Novartis Ag |
Fibroblast growth factor 21 mutations
|
|
WO2012069466A1
(en)
|
2010-11-24 |
2012-05-31 |
Novartis Ag |
Multispecific molecules
|
|
EP2647706B1
(en)
|
2010-11-30 |
2023-05-17 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly
|
|
NZ611428A
(en)
|
2010-12-08 |
2015-07-31 |
Stemcentrx Inc |
Novel modulators and methods of use
|
|
US9505826B2
(en)
|
2010-12-22 |
2016-11-29 |
Teva Pharmaceuticals Australia Pty Ltd |
Modified antibody with improved half-life
|
|
WO2012092539A2
(en)
|
2010-12-31 |
2012-07-05 |
Takeda Pharmaceutical Company Limited |
Antibodies to dll4 and uses thereof
|
|
KR101276801B1
(ko)
|
2011-01-21 |
2013-06-19 |
한화엘앤씨 주식회사 |
ｓＴＮＦＲ1-Ｆｃ 유전자를 발현하는 형질전환 돼지 및 이의 용도
|
|
US9540443B2
(en)
|
2011-01-26 |
2017-01-10 |
Kolltan Pharmaceuticals, Inc. |
Anti-kit antibodies
|
|
US10689447B2
(en)
|
2011-02-04 |
2020-06-23 |
Genentech, Inc. |
Fc variants and methods for their production
|
|
SA112330278B1
(ar)
|
2011-02-18 |
2015-10-09 |
ستيم سينتركس، انك. |
مواد ضابطة جديدة وطرق للاستخدام
|
|
MX352889B
(es)
|
2011-02-25 |
2017-12-13 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo de fc especifico para fcyriib.
|
|
TWI719112B
(zh)
|
2011-03-16 |
2021-02-21 |
賽諾菲公司 |
雙重ｖ區類抗體蛋白質之用途
|
|
PH12013501865A1
(en)
|
2011-03-16 |
2014-01-06 |
Amgen Inc |
Potent and selective inhibitors of nav1.3 and nav1.7
|
|
ES2692268T5
(en)
|
2011-03-29 |
2025-02-26 |
Roche Glycart Ag |
Antibody fc variants
|
|
EP3415528B1
(en)
|
2011-04-13 |
2021-05-26 |
Bristol-Myers Squibb Company |
Fc fusion proteins comprising novel linkers or arrangements
|
|
WO2015067913A1
(en)
|
2013-11-07 |
2015-05-14 |
Diagnodus Limited |
Biomarkers
|
|
BR112013029892A2
(pt)
|
2011-05-21 |
2016-12-20 |
Macrogenics Inc |
polipeptídeo, molécula de ligação a antígeno, diacorpo e uso de uma porção polipeptídica de uma proteína de ligação a soro desimunizada
|
|
AU2012258907A1
(en)
|
2011-05-25 |
2013-11-07 |
Merck Sharp & Dohme Corp. |
Method for preparing Fc-containing polypeptides having improved properties
|
|
UA113626C2
(xx)
|
2011-06-02 |
2017-02-27 |
|
Композиція для лікування діабету, що містить кон'югат інсуліну тривалої дії та кон'югат інсулінотропного пептиду тривалої дії
|
|
CN103732623B
(zh)
|
2011-06-03 |
2017-09-29 |
佐马技术有限公司 |
对TGF‑β具有特异性的抗体
|
|
US9244074B2
(en)
|
2011-06-07 |
2016-01-26 |
University Of Hawaii |
Biomarker of asbestos exposure and mesothelioma
|
|
WO2012170742A2
(en)
|
2011-06-07 |
2012-12-13 |
University Of Hawaii |
Treatment and prevention of cancer with hmgb1 antagonists
|
|
UA126465C2
(uk)
|
2011-06-10 |
2022-10-12 |
Ханмі Сайенс Ко., Лтд. |
Пептид, що має активність оксинтомодуліну, та фармацевтична композиція для лікування ожиріння, яка його містить
|
|
WO2012172495A1
(en)
|
2011-06-14 |
2012-12-20 |
Novartis Ag |
Compositions and methods for antibodies targeting tem8
|
|
RU2607365C2
(ru)
|
2011-06-17 |
2017-01-10 |
Ханми Сайенс Ко., Лтд. |
Конъюгат, содержащий оксинтомодулин и фрагмент иммуноглобулина, и его применение
|
|
PL2726508T3
(pl)
|
2011-06-28 |
2017-12-29 |
Oxford Biotherapeutics Ltd |
Przeciwciała przeciwko cyklazie ADP-rybozylowej 2
|
|
TWI687439B
(zh)
|
2011-06-30 |
2020-03-11 |
中外製藥股份有限公司 |
異源二聚化多胜肽
|
|
BR112014001274A2
(pt)
|
2011-07-18 |
2017-04-18 |
Arts Biologics As |
composto de hormônio luteinizante, e, composição farmacêutica
|
|
GB201112429D0
(en)
|
2011-07-19 |
2011-08-31 |
Glaxo Group Ltd |
Antigen-binding proteins with increased FcRn binding
|
|
US20130058947A1
(en)
|
2011-09-02 |
2013-03-07 |
Stem Centrx, Inc |
Novel Modulators and Methods of Use
|
|
CN111053918A
(zh)
|
2011-09-05 |
2020-04-24 |
韩美科学株式会社 |
一种包含干扰素α-缀合物的抗癌用药物组合物
|
|
UY34347A
(es)
|
2011-09-26 |
2013-04-30 |
Novartis Ag |
Proteínas de función dual para tratar trastornos metabólicos
|
|
TWI593708B
(zh)
|
2011-09-26 |
2017-08-01 |
諾華公司 |
治療代謝病症之融合蛋白質
|
|
RU2014117505A
(ru)
|
2011-09-30 |
2015-11-10 |
Чугаи Сейяку Кабусики Кайся |
Антигенсвязывающая молекула для ускорения удаления антигенов
|
|
HUE034044T2
(en)
|
2011-09-30 |
2018-01-29 |
Dana Farber Cancer Inst Inc |
Therapeutic peptides
|
|
TW201817744A
(zh)
|
2011-09-30 |
2018-05-16 |
日商中外製藥股份有限公司 |
具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子
|
|
JP6322411B2
(ja)
|
2011-09-30 |
2018-05-09 |
中外製薬株式会社 |
複数の生理活性を有する抗原の消失を促進する抗原結合分子
|
|
US9221907B2
(en)
|
2011-11-01 |
2015-12-29 |
Bionomics Inc. |
Anti-GPR49 monoclonal antibodies
|
|
US10598653B2
(en)
|
2011-11-01 |
2020-03-24 |
Bionomics Inc. |
Methods of blocking cancer stem cell growth
|
|
CN104053671A
(zh)
|
2011-11-01 |
2014-09-17 |
生态学有限公司 |
治疗癌症的抗体和方法
|
|
WO2013067057A1
(en)
|
2011-11-01 |
2013-05-10 |
Bionomics, Inc. |
Anti-gpr49 antibodies
|
|
KR20130049671A
(ko)
|
2011-11-04 |
2013-05-14 |
한미사이언스 주식회사 |
생리활성 폴리펩타이드 결합체 제조 방법
|
|
BR112014010580B1
(pt)
|
2011-11-04 |
2021-01-12 |
Zymeworks, Inc. |
constructo de fc heteromultimérico isolado, composição, uso de um constructo de fc heteromultimérico isolado, composição de ácido nucléico e método para expressar o constructo de fc heteromultimérico isolado
|
|
ES2666856T3
(es)
|
2011-11-04 |
2018-05-08 |
Novartis Ag |
Proteína 6 relacionada con lipoproteínas de baja densidad (LRP6) - constructos extensores de la vida media
|
|
WO2013068571A1
(en)
|
2011-11-11 |
2013-05-16 |
Ucb Pharma S.A. |
Albumin binding antibodies and binding fragments thereof
|
|
CN104185477B
(zh)
|
2011-11-17 |
2017-05-24 |
辉瑞公司 |
细胞毒性肽及其抗体‑药物缀合物
|
|
KR20230143201A
(ko)
|
2011-11-30 |
2023-10-11 |
추가이 세이야쿠 가부시키가이샤 |
면역 복합체를 형성하는 세포내로의 운반체（캐리어）를 포함하는 의약
|
|
CN104105709A
(zh)
|
2011-12-05 |
2014-10-15 |
诺华股份有限公司 |
抗her3的结构域ii的表皮生长因子受体3(her3)抗体
|
|
EP3590538A1
(en)
|
2011-12-05 |
2020-01-08 |
Novartis AG |
Antibodies for epidermal growth factor receptor 3 (her3)
|
|
WO2013096516A1
(en)
|
2011-12-19 |
2013-06-27 |
Xoma Technology Ltd. |
Methods for treating acne
|
|
ES2728278T3
(es)
|
2011-12-21 |
2019-10-23 |
Novartis Ag |
Composiciones que comprenden anticuerpos dirigidos al factor P y C5
|
|
JP2015502397A
(ja)
|
2011-12-23 |
2015-01-22 |
ファイザー・インク |
部位特異的コンジュゲーションのための操作された抗体定常領域、ならびにそのための方法および使用
|
|
KR101895047B1
(ko)
|
2011-12-30 |
2018-09-06 |
한미사이언스 주식회사 |
면역글로불린 단편을 이용한 위치 특이적 글루카곤 유사 펩타이드-2 약물 결합체
|
|
JP2015509091A
(ja)
|
2012-01-09 |
2015-03-26 |
ザ スクリプス リサーチ インスティテュート |
ヒト化抗体
|
|
CA2863224A1
(en)
|
2012-01-09 |
2013-07-18 |
The Scripps Research Institute |
Ultralong complementarity determining regions and uses thereof
|
|
SG11201404751UA
(en)
|
2012-02-09 |
2014-09-26 |
Chugai Pharmaceutical Co Ltd |
Modified fc region of antibody
|
|
EP3738980A1
(en)
|
2012-02-24 |
2020-11-18 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule for promoting disappearance of antigen via fc gamma riib
|
|
BR112014020826A8
(pt)
|
2012-02-24 |
2017-09-19 |
Stem Centrx Inc |
Anticorpo que se liga especificamente a um epítopo, ácido nucleico, vetor ou célula hospedeira, conjugado de fármaco anticorpo, composição farmacêutica compreendendo o referido anticorpo, uso do mesmo, kit e método de preparação do conjugado
|
|
NZ629684A
(en)
|
2012-03-05 |
2016-10-28 |
Gilead Calistoga Llc |
Polymorphic forms of (s)-2-(1-(9h-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3h)-one
|
|
AR090281A1
(es)
|
2012-03-08 |
2014-10-29 |
Hanmi Science Co Ltd |
Proceso mejorado para la preparacion de un complejo polipeptidico fisiologicamente activo
|
|
KR101665009B1
(ko)
|
2012-03-09 |
2016-10-11 |
한미사이언스 주식회사 |
비알콜성 지방간 질환의 예방 또는 치료용 약학적 조성물
|
|
US9592289B2
(en)
|
2012-03-26 |
2017-03-14 |
Sanofi |
Stable IgG4 based binding agent formulations
|
|
US10064951B2
(en)
|
2012-03-30 |
2018-09-04 |
Hanmi Science Co., Ltd. |
Liquid formulation of highly concentrated long-acting human growth hormone conjugate
|
|
WO2013169693A1
(en)
|
2012-05-09 |
2013-11-14 |
Bristol-Myers Squibb Company |
Methods of treating cancer using an il-21 polypeptide and an anti-pd-1 antibody
|
|
AU2013258834B2
(en)
|
2012-05-10 |
2017-09-07 |
Zymeworks Bc Inc. |
Heteromultimer constructs of immunoglobulin heavy chains with mutations in the Fc domain
|
|
GB201208370D0
(en)
*
|
2012-05-14 |
2012-06-27 |
Ucb Pharma Sa |
Antibodies
|
|
WO2013173337A2
(en)
|
2012-05-15 |
2013-11-21 |
Seattle Genetics, Inc. |
Self-stabilizing linker conjugates
|
|
RU2625771C2
(ru)
*
|
2012-05-23 |
2017-07-18 |
Дженентек, Инк. |
Способ отбора терапевтических средств
|
|
WO2013180200A1
(ja)
|
2012-05-30 |
2013-12-05 |
中外製薬株式会社 |
標的組織特異的抗原結合分子
|
|
EP2857419B1
(en)
|
2012-05-30 |
2021-01-13 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule for eliminating aggregated antigens
|
|
US9499634B2
(en)
|
2012-06-25 |
2016-11-22 |
Zymeworks Inc. |
Process and methods for efficient manufacturing of highly pure asymmetric antibodies in mammalian cells
|
|
WO2014004549A2
(en)
|
2012-06-27 |
2014-01-03 |
Amgen Inc. |
Anti-mesothelin binding proteins
|
|
SG11201408538PA
(en)
|
2012-07-13 |
2015-02-27 |
Roche Glycart Ag |
Bispecific anti-vegf/anti-ang-2 antibodies and their use in the treatment of ocular vascular diseases
|
|
EP2875046B2
(en)
|
2012-07-19 |
2025-04-30 |
Amgen Inc. |
Human btnl3 proteins, nucleic acids, and antibodies and uses thereof
|
|
NZ630363A
(en)
|
2012-07-25 |
2018-09-28 |
Celldex Therapeutics Inc |
Anti-kit antibodies and uses thereof
|
|
KR101968344B1
(ko)
|
2012-07-25 |
2019-04-12 |
한미약품 주식회사 |
옥신토모듈린 유도체를 포함하는 고지혈증 치료용 조성물
|
|
AR091902A1
(es)
|
2012-07-25 |
2015-03-11 |
Hanmi Pharm Ind Co Ltd |
Formulacion liquida de un conjugado de insulina de accion prolongada
|
|
AR092862A1
(es)
|
2012-07-25 |
2015-05-06 |
Hanmi Pharm Ind Co Ltd |
Formulacion liquida de insulina de accion prolongada y un peptido insulinotropico y metodo de preparacion
|
|
SG10201709559PA
(en)
|
2012-08-24 |
2017-12-28 |
Chugai Pharmaceutical Co Ltd |
Fcγriib-specific fc region variant
|
|
CA2887129A1
(en)
|
2012-10-09 |
2014-04-17 |
Igenica, Inc. |
Anti-c16orf54 antibodies and methods of use thereof
|
|
CN105121421B
(zh)
|
2012-11-05 |
2020-10-02 |
辉瑞公司 |
司普力西欧他汀类似物
|
|
WO2014073842A1
(en)
|
2012-11-06 |
2014-05-15 |
Hanmi Pharm. Co., Ltd. |
Liquid formulation of protein conjugate comprising the oxyntomodulin and an immunoglobulin fragment
|
|
KR101993393B1
(ko)
|
2012-11-06 |
2019-10-01 |
한미약품 주식회사 |
옥신토모듈린 유도체를 포함하는 당뇨병 또는 비만성 당뇨병 치료용 조성물
|
|
CA2890571A1
(en)
|
2012-11-07 |
2014-05-15 |
Kenneth G. Geles |
Anti-notch3 antibodies and antibody-drug conjugates
|
|
UY35144A
(es)
|
2012-11-20 |
2014-06-30 |
Novartis Ag |
Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca
|
|
US9914785B2
(en)
|
2012-11-28 |
2018-03-13 |
Zymeworks Inc. |
Engineered immunoglobulin heavy chain-light chain pairs and uses thereof
|
|
WO2014084859A1
(en)
|
2012-11-30 |
2014-06-05 |
Novartis Ag |
Molecules and methods for modulating tmem16a activities
|
|
WO2014089177A2
(en)
|
2012-12-04 |
2014-06-12 |
Massachusetts Institute Of Technology |
Compounds, conjugates and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines
|
|
DK2928921T3
(da)
|
2012-12-05 |
2021-04-19 |
Novartis Ag |
Sammensætninger og fremgangsmåder til antistoffer målrettet epo
|
|
BR112015017619A2
(pt)
|
2013-01-24 |
2017-11-21 |
Glaxosmithkline Ip Dev Ltd |
formulação líquida, uso de uma formulação, e, kit
|
|
KR102073748B1
(ko)
|
2013-01-31 |
2020-02-05 |
한미약품 주식회사 |
재조합 효모 형질전환체 및 이를 이용하여 면역글로불린 단편을 생산하는 방법
|
|
US10065987B2
(en)
|
2013-02-12 |
2018-09-04 |
Bristol-Myers Squibb Company |
High pH protein refolding methods
|
|
WO2014126871A1
(en)
|
2013-02-12 |
2014-08-21 |
Bristol-Myers Squibb Company |
Tangential flow filtration based protein refolding methods
|
|
WO2014129895A1
(en)
|
2013-02-19 |
2014-08-28 |
Stichting Vu-Vumc |
Means and method for increasing the sensitivity of cancers for radiotherapy
|
|
ES2731681T3
(es)
|
2013-02-22 |
2019-11-18 |
Abbvie Stemcentrx Llc |
Conjugados de anticuerpo anti-DLL3 y PBD y usos de los mismos
|
|
DK2963056T3
(da)
|
2013-02-26 |
2020-02-17 |
Hanmi Pharm Ind Co Ltd |
Insulinanalog og anvendelse deraf
|
|
MX361083B
(es)
|
2013-02-26 |
2018-11-27 |
Hanmi Pharma Co Ltd |
Conjugado de insulina específico de sitio.
|
|
MY186423A
(en)
|
2013-03-05 |
2021-07-22 |
Hanmi Pharm Ind Co Ltd |
Improved preparation method for high-yield production of physiologically active polypeptide conjugate
|
|
US9487587B2
(en)
|
2013-03-05 |
2016-11-08 |
Macrogenics, Inc. |
Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof
|
|
AU2014224174B2
(en)
|
2013-03-06 |
2018-08-30 |
Hadasit Medical Research Services And Development Ltd. |
Use of plant cells expressing a TNFalpha polypeptide inhibitor in therapy
|
|
US20160017021A1
(en)
|
2013-03-06 |
2016-01-21 |
Protalix Ltd. |
TNF alpha INHIBITOR POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME, CELLS EXPRESSING SAME AND METHODS OF PRODUCING SAME
|
|
WO2014165277A2
(en)
|
2013-03-12 |
2014-10-09 |
Amgen Inc. |
POTENT AND SELECTIVE INHIBITORS OF Nav1.7
|
|
EP2970940B1
(en)
|
2013-03-14 |
2018-07-25 |
Translate Bio, Inc. |
Mrna therapeutic compositions and use to treat diseases and disorders
|
|
EP3611189A1
(en)
|
2013-03-14 |
2020-02-19 |
Novartis AG |
Antibodies against notch 3
|
|
SMT202100464T1
(it)
|
2013-03-14 |
2021-11-12 |
Macrogenics Inc |
Molecole bispecifiche che sono immunoreattive con cellule effettrici immunitarie che esprimono un recettore di attivazione
|
|
MX2015012563A
(es)
|
2013-03-15 |
2016-10-26 |
Abbvie Biotechnology Ltd |
Anticuerpos anti-cd25 y sus usos.
|
|
HK1220626A1
(zh)
|
2013-03-15 |
2017-05-12 |
The Centre For Drug Research And Development |
具细胞毒性和抗有丝分裂的化合物以及其使用方法
|
|
HK1220470A1
(zh)
|
2013-03-15 |
2017-05-05 |
Abbvie Biotechnology Ltd. |
抗cd25抗体及其用途
|
|
SG11201506766PA
(en)
|
2013-03-15 |
2015-09-29 |
Dana Farber Cancer Inst Inc |
Therapeutic peptides
|
|
US20140377253A1
(en)
|
2013-03-15 |
2014-12-25 |
Abbvie Biotherapeutics Inc. |
Fc variants
|
|
EP2978451B1
(en)
|
2013-03-29 |
2019-11-27 |
Alexion Pharmaceuticals, Inc. |
Compositions and methods for increasing the serum half-life of a therapeutic agent targeting complement c5
|
|
CN105246914B
(zh)
|
2013-04-02 |
2021-08-27 |
中外制药株式会社 |
Fc区变体
|
|
WO2014177459A2
(en)
|
2013-04-29 |
2014-11-06 |
F. Hoffmann-La Roche Ag |
Fc-receptor binding modified asymmetric antibodies and methods of use
|
|
UA118029C2
(uk)
|
2013-04-29 |
2018-11-12 |
Ф. Хоффманн-Ля Рош Аг |
Модифіковане антитіло, що зв'язується з людським fcrn, й способи його застосування
|
|
KR101895634B1
(ko)
|
2013-05-31 |
2018-09-05 |
한미약품 주식회사 |
변이된 힌지 영역을 포함하는 IgG4 Fc 단편
|
|
SG11201509982UA
(enExample)
|
2013-06-06 |
2016-04-28 |
Igenica Biotherapeutics Inc |
|
|
CN105636984A
(zh)
|
2013-06-13 |
2016-06-01 |
法斯特弗沃德制药有限公司 |
用于治疗慢性炎症和预防胃肠道癌或纤维化的cd40信号转导抑制剂和其他化合物，该其他化合物是胆汁酸、胆汁酸衍生物、tgr5受体激动剂、fxr激动剂或其组合
|
|
AR096601A1
(es)
|
2013-06-21 |
2016-01-20 |
Novartis Ag |
Anticuerpos del receptor 1 de ldl oxidado similar a lectina y métodos de uso
|
|
UY35620A
(es)
|
2013-06-21 |
2015-01-30 |
Novartis Ag |
Anticuerpos del receptor 1 de ldl oxidado similar a lectina y métodos de uso
|
|
AR096890A1
(es)
|
2013-07-12 |
2016-02-03 |
Hanmi Pharm Ind Co Ltd |
Conjugando fc de inmunoglobulina, que mantiene la afinidad de unión del fragmento fc de la inmunoglobulina a fcrn
|
|
AR096891A1
(es)
|
2013-07-12 |
2016-02-03 |
Hanmi Pharm Ind Co Ltd |
Conjugado de monómero polipéptido biológicamente activo y conjugado de fragmento fc de inmunoglobulina, que muestra aclaramiento mediado por receptor reducido, y el método para la preparación del mismo
|
|
CA2918370A1
(en)
|
2013-07-18 |
2015-01-22 |
Fabrus, Inc. |
Humanized antibodies with ultralong complementarity determining regions
|
|
WO2015017146A2
(en)
|
2013-07-18 |
2015-02-05 |
Fabrus, Inc. |
Antibodies with ultralong complementarity determining regions
|
|
HK1218252A1
(zh)
|
2013-07-25 |
2017-02-10 |
Novartis Ag |
合成apelin多肽之生物结合物
|
|
KR20160031551A
(ko)
|
2013-07-25 |
2016-03-22 |
노파르티스 아게 |
심부전의 치료를 위한 시클릭 폴리펩티드
|
|
AU2014296288B2
(en)
|
2013-07-31 |
2020-02-13 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for modulating thermogenesis using PTH-related and EGF-related molecules
|
|
US11384149B2
(en)
|
2013-08-09 |
2022-07-12 |
Macrogenics, Inc. |
Bi-specific monovalent Fc diabodies that are capable of binding CD32B and CD79b and uses thereof
|
|
UA116479C2
(uk)
|
2013-08-09 |
2018-03-26 |
Макродженікс, Інк. |
БІСПЕЦИФІЧНЕ МОНОВАЛЕНТНЕ Fc-ДІАТІЛО, ЯКЕ ОДНОЧАСНО ЗВ'ЯЗУЄ CD32B I CD79b, ТА ЙОГО ЗАСТОСУВАННЯ
|
|
EP2840091A1
(en)
|
2013-08-23 |
2015-02-25 |
MacroGenics, Inc. |
Bi-specific diabodies that are capable of binding gpA33 and CD3 and uses thereof
|
|
EP2839842A1
(en)
|
2013-08-23 |
2015-02-25 |
MacroGenics, Inc. |
Bi-specific monovalent diabodies that are capable of binding CD123 and CD3 and uses thereof
|
|
AU2014332442B2
(en)
|
2013-08-26 |
2019-12-19 |
Biontech Research And Development, Inc. |
Nucleic acids encoding human antibodies to Sialyl-Lewis
|
|
CN105792836A
(zh)
|
2013-08-28 |
2016-07-20 |
施特姆森特克斯股份有限公司 |
新型sez6调节剂以及应用方法
|
|
SG11201601424PA
(en)
|
2013-08-28 |
2016-03-30 |
Stemcentrx Inc |
Site-specific antibody conjugation methods and compositions
|
|
WO2015035044A2
(en)
|
2013-09-04 |
2015-03-12 |
Abbvie Biotherapeutics Inc. |
Fc VARIANTS WITH IMPROVED ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY
|
|
EP3689335A1
(en)
|
2013-09-27 |
2020-08-05 |
Hanmi Pharm. Co., Ltd. |
Sustained type human growth hormone preparation
|
|
NZ758049A
(en)
|
2013-10-15 |
2024-03-22 |
Seagen Inc |
Pegylated drug-linkers for improved ligand-drug conjugate pharmacokinetics
|
|
EP3057605A1
(en)
|
2013-10-18 |
2016-08-24 |
Novartis AG |
Methods of treating diabetes and related disorders
|
|
RU2016122041A
(ru)
|
2013-11-06 |
2017-12-11 |
ЭББВИ СТЕМСЕНТРКС ЭлЭлСи |
Новые анти-клаудин антитела и способы их применения
|
|
AU2014357292B2
(en)
|
2013-11-27 |
2020-06-25 |
Zymeworks Bc Inc. |
Bispecific antigen-binding constructs targeting HER2
|
|
EP3077504B1
(en)
|
2013-12-06 |
2019-08-14 |
Dana-Farber Cancer Institute, Inc. |
Therapeutic peptides
|
|
SI3082878T1
(sl)
|
2013-12-19 |
2023-01-31 |
Seagen Inc. |
Metilen-karbamatni linkerji za uporabo s tarčnimi konjugati zdravila
|
|
NZ736970A
(en)
|
2013-12-20 |
2018-11-30 |
Gilead Calistoga Llc |
Process methods for phosphatidylinositol 3-kinase inhibitors
|
|
WO2015095605A1
(en)
|
2013-12-20 |
2015-06-25 |
Gilead Calistoga Llc |
Polymorphic forms of a hydrochloride salt of (s) -2-(9h-purin-6-ylamino) propyl) -5-fluoro-3-phenylquinazolin-4 (3h) -one
|
|
SG11201605203UA
(en)
|
2013-12-24 |
2016-07-28 |
Argen X N V |
Fcrn antagonists and methods of use
|
|
WO2015095953A1
(en)
|
2013-12-27 |
2015-07-02 |
The Centre For Drug Research And Development |
Sulfonamide-containing linkage systems for drug conjugates
|
|
MX380658B
(es)
|
2014-01-15 |
2025-03-11 |
Hoffmann La Roche |
Variantes de region fc con union mejorada de la proteina a.
|
|
RU2727639C2
(ru)
*
|
2014-01-15 |
2020-07-22 |
Ф.Хоффманн-Ля Рош Аг |
Варианты fc-области с модифицированной способностью связываться с fcrn и с сохраненной способностью связываться с белком а
|
|
CR20160376A
(es)
|
2014-01-20 |
2016-10-07 |
Hanmi Pharm Ind Co Ltd |
Insulina de acción prolongada y uso de la misma
|
|
PE20170256A1
(es)
|
2014-01-24 |
2017-04-22 |
Ngm Biopharmaceuticals Inc |
Proteinas de union y sus metodos de uso
|
|
SG11201605437YA
(en)
|
2014-01-27 |
2016-08-30 |
Pfizer |
Bifunctional cytotoxic agents
|
|
CA2937753A1
(en)
|
2014-02-17 |
2015-08-20 |
Seattle Genetics, Inc. |
Hydrophilic antibody-drug conjugates
|
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
|
NZ631007A
(en)
|
2014-03-07 |
2015-10-30 |
Alexion Pharma Inc |
Anti-c5 antibodies having improved pharmacokinetics
|
|
CA2939006A1
(en)
|
2014-03-14 |
2015-09-17 |
Dana-Farber Cancer Institute, Inc. |
Vaccine compositions and methods for restoring nkg2d pathway function against cancers
|
|
MX387560B
(es)
|
2014-03-31 |
2025-03-18 |
Hanmi Pharmaceutical Co Ltd |
Procedimiento para mejorar la solubilidad de proteínas y péptidos usando un enlace del fragmento fc de inmunoglobulina.
|
|
CA2944649C
(en)
|
2014-04-04 |
2022-06-21 |
Bionomics, Inc. |
Humanized antibodies that bind lgr5
|
|
ES2913205T3
(es)
|
2014-05-13 |
2022-06-01 |
Bioatla Inc |
Proteínas biológicas activas condicionalmente
|
|
ES2869459T3
(es)
|
2014-05-16 |
2021-10-25 |
Medimmune Llc |
Moléculas con unión a receptor de fc de neonato alterada que tiene propiedades terapéuticas y de diagnóstico potenciadas
|
|
SI3148579T1
(sl)
|
2014-05-28 |
2021-07-30 |
Agenus Inc. |
Proti GITR antitelesa in postopki z njihovo uporabo
|
|
AR100639A1
(es)
|
2014-05-29 |
2016-10-19 |
Hanmi Pharm Ind Co Ltd |
Composición para tratar diabetes que comprende conjugados de análogos de insulina de acción prolongada y conjugados de péptidos insulinotrópicos de acción prolongada
|
|
AR100695A1
(es)
|
2014-05-30 |
2016-10-26 |
Hanmi Pharm Ind Co Ltd |
Composición para el tratamiento de diabetes mellitus que comprende insulina y un agonista dual glp-1 / glucagón
|
|
US9856324B2
(en)
|
2014-06-04 |
2018-01-02 |
MabVax Therapeutics, Inc. |
Human monoclonal antibodies to ganglioside GD2
|
|
KR20150140177A
(ko)
|
2014-06-05 |
2015-12-15 |
한미약품 주식회사 |
단백질 및 펩타이드의 면역원성을 감소시키는 방법
|
|
PE20170441A1
(es)
|
2014-06-06 |
2017-04-26 |
Bristol Myers Squibb Co |
Anticuerpos contra el receptor del factor de necrosis tumoral inducido por glucocorticoides (gitr) y sus usos
|
|
WO2015191781A2
(en)
|
2014-06-10 |
2015-12-17 |
Amgen Inc. |
Apelin polypeptides
|
|
MA40059A
(fr)
|
2014-06-13 |
2015-12-17 |
Gilead Sciences Inc |
Inhibiteurs de la phosphatidylinositol 3-kinase
|
|
SG11201609706VA
(en)
|
2014-06-23 |
2017-01-27 |
Novartis Ag |
Site specific protein modifications
|
|
KR102762243B1
(ko)
|
2014-06-30 |
2025-02-05 |
알토 바이오사이언스 엘엘씨 |
Il-15-베이즈드 분자 및 이의 사용 방법
|
|
WO2016020880A2
(en)
|
2014-08-07 |
2016-02-11 |
Novartis Ag |
Angiopoietin-like 4 antibodies and methods of use
|
|
WO2016020882A2
(en)
|
2014-08-07 |
2016-02-11 |
Novartis Ag |
Angiopoetin-like 4 (angptl4) antibodies and methods of use
|
|
EA202193002A2
(ru)
|
2014-09-03 |
2022-03-31 |
Бёрингер Ингельхайм Интернациональ Гмбх |
Соединение, нацеленное на ил-23a и фно-альфа, и его применение
|
|
WO2016036916A1
(en)
|
2014-09-03 |
2016-03-10 |
Bioatla, Llc |
Discovering and producing conditionally active biologic proteins in the same eukaryotic cell production hosts
|
|
TW201617368A
(zh)
|
2014-09-05 |
2016-05-16 |
史坦森特瑞斯公司 |
新穎抗ｍｆｉ２抗體及使用方法
|
|
WO2016044224A1
(en)
|
2014-09-15 |
2016-03-24 |
Amgen Inc. |
Bi-specific anti-cgrp receptor/pac1 receptor antigen binding proteins and uses thereof
|
|
TWI802396B
(zh)
|
2014-09-16 |
2023-05-11 |
南韓商韓美藥品股份有限公司 |
長效glp-1/高血糖素受體雙促效劑治療非酒精性脂肝疾病之用途
|
|
ES2905569T3
(es)
|
2014-09-17 |
2022-04-11 |
Zymeworks Inc |
Compuestos citotóxicos y antimitóticos y métodos para utilizarlos
|
|
MX386297B
(es)
|
2014-09-29 |
2025-03-18 |
Univ Duke |
Moleculas biespecificas que comprenden un brazo orientado a la envoltura vih-1.
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
AU2015349878A1
(en)
|
2014-11-21 |
2017-05-25 |
Bristol-Myers Squibb Company |
Antibodies against CD73 and uses thereof
|
|
JP6668345B2
(ja)
|
2014-11-21 |
2020-03-18 |
ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ |
修飾された重鎖定常領域を含む抗体
|
|
GB201421901D0
(en)
|
2014-12-09 |
2015-01-21 |
Cambridge Entpr Ltd |
A method of rational antibody design
|
|
JP6800853B2
(ja)
|
2014-12-11 |
2020-12-16 |
ピエール、ファーブル、メディカマン |
抗ｃ１０ｏｒｆ５４抗体およびその使用
|
|
US20160168237A1
(en)
|
2014-12-12 |
2016-06-16 |
Alexion Pharmaceuticals, Inc. |
Method for treating a complement mediated disorder caused by an infectious agent in a patient
|
|
KR101860280B1
(ko)
|
2014-12-19 |
2018-05-21 |
추가이 세이야쿠 가부시키가이샤 |
항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법
|
|
UY36449A
(es)
|
2014-12-19 |
2016-07-29 |
Novartis Ag |
Composiciones y métodos para anticuerpos dirigidos a bmp6
|
|
CA2972048C
(en)
|
2014-12-22 |
2023-03-07 |
The Rockefeller University |
Anti-mertk agonistic antibodies and uses thereof
|
|
JP6180663B2
(ja)
|
2014-12-23 |
2017-08-16 |
ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ |
Ｔｉｇｉｔに対する抗体
|
|
PE20171154A1
(es)
|
2014-12-30 |
2017-08-16 |
Hanmi Pharm Ind Co Ltd |
Derivados de glucagon con estabilidad mejorada
|
|
KR102418477B1
(ko)
|
2014-12-30 |
2022-07-08 |
한미약품 주식회사 |
글루카곤 유도체
|
|
WO2016115345A1
(en)
|
2015-01-14 |
2016-07-21 |
The Brigham And Women's Hospital, |
Treatment of cancer with anti-lap monoclonal antibodies
|
|
CN107428818A
(zh)
|
2015-01-29 |
2017-12-01 |
密西根州立大学校董会 |
隐藏多肽及其用途
|
|
KR102605798B1
(ko)
|
2015-02-05 |
2023-11-23 |
추가이 세이야쿠 가부시키가이샤 |
이온 농도 의존적 항원 결합 도메인을 포함하는 항체, Fc 영역 개변체, IL-8에 결합하는 항체, 및 그들의 사용
|
|
EP3260139A4
(en)
|
2015-02-17 |
2018-09-05 |
Hanmi Pharm. Co., Ltd. |
Long-acting insulin or insulin analogue complex
|
|
EP3262217A4
(en)
|
2015-02-24 |
2018-07-18 |
BioAtla LLC |
Conditionally active biological proteins
|
|
KR20250005465A
(ko)
|
2015-03-03 |
2025-01-09 |
키맵 리미티드 |
항체, 용도 및 방법
|
|
US10711067B2
(en)
|
2015-03-03 |
2020-07-14 |
Xoma (Us) Llc |
Treatment of post-prandial hyperinsulinemia and hypoglycemia after bariatric surgery
|
|
US10870706B2
(en)
|
2015-03-20 |
2020-12-22 |
Pfizer Inc. |
Bifunctional cytotoxic agents containing the CTI pharmacophore
|
|
DK3303396T5
(da)
|
2015-05-29 |
2024-10-07 |
Bristol Myers Squibb Co |
Antistoffer mod ox40 og anvendelser deraf
|
|
EP3303387A2
(en)
|
2015-06-05 |
2018-04-11 |
Novartis AG |
Antibodies targeting bone morphogenetic protein 9 (bmp9) and methods therefor
|
|
UY36751A
(es)
|
2015-06-26 |
2017-01-31 |
Novartis Ag |
Anticuerpos de factor xi y métodos de uso
|
|
CN107922500A
(zh)
|
2015-06-29 |
2018-04-17 |
洛克菲勒大学 |
具有增强的激动剂活性的抗cd40抗体
|
|
EP4523705A3
(en)
|
2015-06-30 |
2025-06-11 |
Hanmi Pharm. Co., Ltd. |
Glucagon derivative and a composition comprising a long acting conjugate of the same
|
|
US11236159B2
(en)
|
2015-08-03 |
2022-02-01 |
Novartis Ag |
Methods of treating FGF21-associated disorders
|
|
EP3331549B1
(en)
|
2015-08-06 |
2020-12-23 |
President and Fellows of Harvard College |
Improved microbe-binding molecules and uses thereof
|
|
UY36870A
(es)
|
2015-08-28 |
2017-03-31 |
Hanmi Pharm Ind Co Ltd |
Análogos de insulina novedosos
|
|
AU2016317915B2
(en)
|
2015-09-01 |
2021-02-18 |
Agenus Inc. |
Anti-PD-1 antibodies and methods of use thereof
|
|
EA038332B1
(ru)
|
2015-09-09 |
2021-08-10 |
Новартис Аг |
Молекулы, связывающиеся с тимусным стромальным лимфопоэтином (tslp), и способы применения таких молекул
|
|
HRP20210650T1
(hr)
|
2015-09-09 |
2021-05-28 |
Novartis Ag |
Protutijela koja vežu timusni stromalni limfopoetin (tslp) i postupci uporabe protutijela
|
|
CA2998174A1
(en)
|
2015-09-15 |
2017-03-23 |
Amgen Inc. |
Tetravalent bispecific and tetraspecific antigen binding proteins and uses thereof
|
|
WO2017052329A1
(en)
|
2015-09-24 |
2017-03-30 |
Hanmi Pharm. Co., Ltd. |
Protein complex by use of a specific site of an immunoglobulin fragment for linkage
|
|
BR112018006237A2
(pt)
|
2015-09-29 |
2018-10-09 |
Celgene Corp |
proteínas de ligação a pd-1 e métodos de uso das mesmas
|
|
EP3356415B1
(en)
|
2015-09-29 |
2024-05-01 |
Amgen Inc. |
Asgr inhibitors for reduzing cholesterol levels
|
|
US20180280474A1
(en)
|
2015-10-01 |
2018-10-04 |
Amgen Inc. |
Treatment of bile acid disorders
|
|
CN107029242A
(zh)
|
2015-11-03 |
2017-08-11 |
财团法人工业技术研究院 |
抗体药物复合物及其制造方法
|
|
MX2018005232A
(es)
|
2015-11-03 |
2018-08-15 |
Ambrx Inc |
Anticuerpos anti-cd3 novedosos y sus usos.
|
|
AU2016356780A1
(en)
|
2015-11-19 |
2018-06-28 |
Bristol-Myers Squibb Company |
Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof
|
|
AU2016365117A1
(en)
|
2015-11-30 |
2018-05-31 |
Abbvie Biotherapeutics Inc. |
Anti-huLRRC15 antibody drug conjugates and methods for their use
|
|
AU2016365114A1
(en)
|
2015-11-30 |
2018-05-17 |
Abbvie Biotherapeutics Inc. |
Anti-huLRRC15 antibody drug conjugates and methods for their use
|
|
CN108883173B
(zh)
|
2015-12-02 |
2022-09-06 |
阿吉纳斯公司 |
抗体和其使用方法
|
|
RU2018124307A
(ru)
|
2015-12-04 |
2020-01-14 |
Новартис Аг |
Антительно-цитокиновые привитые композиции и способы применения для иммунорегуляции
|
|
KR20180090290A
(ko)
|
2015-12-04 |
2018-08-10 |
시애틀 지네틱스, 인크. |
사차화 튜불리신 화합물들의 컨쥬게이트들
|
|
WO2017096262A1
(en)
|
2015-12-04 |
2017-06-08 |
Jomoco, Corp. |
Compositions and methods to mitigate or prevent an immune response to an immunogenic therapeutic molecule in non-human primates
|
|
US10822408B2
(en)
|
2015-12-15 |
2020-11-03 |
Amgen Inc. |
PACAP antibodies and uses thereof
|
|
CR20180365A
(es)
|
2015-12-16 |
2018-09-28 |
Amgen Inc |
PROTEÍNAS DE UNIÓN AL ANTÍGENO BISPECÍFICO DE ANTI-TL1A/ANTI-TNF-a Y SUS USOS
|
|
RU2018126297A
(ru)
|
2015-12-18 |
2020-01-22 |
Новартис Аг |
Антитела, нацеленные на cd32b, и способы их применения
|
|
WO2017110981A1
(en)
|
2015-12-25 |
2017-06-29 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-myostatin antibodies and methods of use
|
|
SG11201805586SA
(en)
|
2015-12-31 |
2018-07-30 |
Hanmi Pharmaceutical Co Ltd |
Triple glucagon/glp-1/gip receptor agonist
|
|
WO2017122130A1
(en)
|
2016-01-11 |
2017-07-20 |
Novartis Ag |
Immune-stimulating humanized monoclonal antibodies against human interleukin-2, and fusion proteins thereof
|
|
MA55746A
(fr)
|
2016-01-21 |
2022-03-02 |
Novartis Ag |
Molécules multispécifiques ciblant cll-1
|
|
AR107483A1
(es)
|
2016-01-29 |
2018-05-02 |
Hanmi Pharm Ind Co Ltd |
Conjugado de enzimas terapéuticas
|
|
EP3411371A1
(en)
|
2016-02-01 |
2018-12-12 |
Pfizer Inc |
Tubulysin analogs and methods for their preparation
|
|
ES2985566T3
(es)
|
2016-03-04 |
2024-11-06 |
Univ Rockefeller |
Anticuerpos contra CD40 con actividad agonista mejorada
|
|
EP3423494A1
(en)
|
2016-03-04 |
2019-01-09 |
Bristol-Myers Squibb Company |
Combination therapy with anti-cd73 antibodies
|
|
JP6937773B2
(ja)
|
2016-03-07 |
2021-09-22 |
ハンミ ファーマシューティカル カンパニー リミテッド |
ポリエチレングリコール誘導体及びその用途
|
|
AU2017234679A1
(en)
|
2016-03-16 |
2018-08-30 |
Merrimack Pharmaceuticals, Inc. |
Engineered trail for cancer therapy
|
|
WO2017161414A1
(en)
|
2016-03-22 |
2017-09-28 |
Bionomics Limited |
Administration of an anti-lgr5 monoclonal antibody
|
|
CN109843919A
(zh)
|
2016-03-25 |
2019-06-04 |
西雅图基因公司 |
用于制备聚乙二醇化的药物-接头及其中间体的方法
|
|
JP2019513371A
(ja)
|
2016-04-01 |
2019-05-30 |
アビディティー バイオサイエンシーズ エルエルシー |
核酸ポリペプチド組成物とその使用
|
|
EP3452510A4
(en)
|
2016-04-04 |
2020-01-15 |
Bioverativ USA Inc. |
ANTI-COMPLEMENT FACTOR BB ANTIBODIES AND USES THEREOF
|
|
GEP20227398B
(en)
|
2016-04-15 |
2022-07-25 |
Macrogenics Inc |
Novel b7-h3 binding molecules, antibody drug conjugates thereof and usage thereof
|
|
JP2019522960A
(ja)
|
2016-04-21 |
2019-08-22 |
アッヴィ・ステムセントルクス・エル・エル・シー |
新規の抗ｂｍｐｒ１ｂ抗体及び使用方法
|
|
WO2017189724A1
(en)
|
2016-04-27 |
2017-11-02 |
Novartis Ag |
Antibodies against growth differentiation factor 15 and uses thereof
|
|
WO2017197045A1
(en)
|
2016-05-11 |
2017-11-16 |
Movassaghi Mohammad |
Convergent and enantioselective total synthesis of communesin analogs
|
|
CA3024618A1
(en)
|
2016-05-27 |
2017-11-30 |
Alexion Pharmaceuticals, Inc. |
Methods for treatment of refractory generalized myasthenia gravis
|
|
EP3464360B1
(en)
|
2016-05-27 |
2025-11-12 |
Agenus Inc. |
Anti-tim-3 antibodies and methods of use thereof
|
|
US10865230B2
(en)
|
2016-05-27 |
2020-12-15 |
Altor Bioscience, Llc |
Construction and characterization of multimeric IL-15-based molecules with CD3 binding domains
|
|
WO2017214452A1
(en)
|
2016-06-08 |
2017-12-14 |
Xencor, Inc. |
Treatment of igg4-related diseases with anti-cd19 antibodies crossbinding to cd32b
|
|
AU2017283787B2
(en)
|
2016-06-15 |
2020-09-17 |
Novartis Ag |
Methods for treating disease using inhibitors of bone morphogenetic protein 6 (BMP6)
|
|
BR112018076247A2
(pt)
|
2016-06-16 |
2019-03-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
anticorpos monoclonais quiméricos e humanizados para cd81
|
|
KR20250175345A
(ko)
|
2016-06-21 |
2025-12-16 |
테네오바이오, 인코포레이티드 |
Cd3 결합 항체
|
|
EP3479841A4
(en)
|
2016-06-29 |
2020-03-04 |
Hanmi Pharm. Co., Ltd. |
GLUCAGON DERIVATIVE, CONJUGATE THEREOF, COMPOSITION THEREOF AND THERAPEUTIC USE THEREOF
|
|
WO2018007999A1
(en)
|
2016-07-08 |
2018-01-11 |
Staten Biotechnology B.V. |
Anti-apoc3 antibodies and methods of use thereof
|
|
CN109757103B
(zh)
|
2016-07-14 |
2024-01-02 |
百时美施贵宝公司 |
针对tim3的抗体及其用途
|
|
HRP20260151T1
(hr)
|
2016-08-02 |
2026-03-27 |
Visterra, Inc. |
Modificirani polipeptidi i njihova uporaba
|
|
WO2018025168A1
(en)
|
2016-08-03 |
2018-02-08 |
Pfizer Inc. |
Heteroaryl sulfone-based conjugation handles, methods for their preparation, and their use in synthesizing antibody drug conjugates
|
|
EP3494991A4
(en)
|
2016-08-05 |
2020-07-29 |
Chugai Seiyaku Kabushiki Kaisha |
COMPOSITION FOR THE PROPHYLAXIS OR TREATMENT OF IL-8 RELATED DISEASES
|
|
TWI851531B
(zh)
|
2016-08-09 |
2024-08-11 |
美商思進公司 |
具有改善之生理化學性質之具自我穩定連接子之藥物結合物
|
|
US10981976B2
(en)
|
2016-08-31 |
2021-04-20 |
University Of Rochester |
Human monoclonal antibodies to human endogenous retrovirus K envelope (HERV-K) and use thereof
|
|
PE20241349A1
(es)
|
2016-09-14 |
2024-07-03 |
Teneobio Inc |
Anticuerpos de union a cd3
|
|
JP2019534859A
(ja)
|
2016-09-19 |
2019-12-05 |
セルジーン コーポレイション |
Ｐｄ−１結合タンパク質を使用して白斑を治療する方法
|
|
MX2019002867A
(es)
|
2016-09-19 |
2019-11-12 |
Celgene Corp |
Metodos de tratamiento de trastornos inmunologicos usando proteinas de union a pd-1.
|
|
JP7158378B2
(ja)
|
2016-09-23 |
2022-10-21 |
ハンミ ファーマシューティカル カンパニー リミテッド |
インスリン受容体との結合力が減少された、インスリンアナログ及びその用途
|
|
JP7066696B2
(ja)
|
2016-10-11 |
2022-05-13 |
アジェナス インコーポレイテッド |
抗ｌａｇ－３抗体及びその使用方法
|
|
CA3039589A1
(en)
|
2016-10-18 |
2018-04-26 |
Seattle Genetics, Inc. |
Targeted delivery of nicotinamide adenine dinucleotide salvage pathway inhibitors
|
|
WO2018075758A1
(en)
|
2016-10-19 |
2018-04-26 |
Alexion Pharmaceuticals, Inc. |
A method of quantitating unbound c5 in a sample
|
|
EP4613776A3
(en)
|
2016-10-21 |
2025-11-26 |
Altor BioScience Corporation |
Multimeric il-15-based molecules
|
|
EP3534947A1
(en)
|
2016-11-03 |
2019-09-11 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses & methods
|
|
MA46770A
(fr)
|
2016-11-09 |
2019-09-18 |
Agenus Inc |
Anticorps anti-ox40, anticorps anti-gitr, et leurs procédés d'utilisation
|
|
MX2019005552A
(es)
|
2016-11-14 |
2019-08-12 |
Amgen Inc |
Proteinas de union a antigenos biespecificas o biparatopicas y usos de las mismas.
|
|
TN2019000164A1
(en)
|
2016-11-23 |
2020-10-05 |
Bioverativ Therapeutics Inc |
Mono- and bispecific antibodies binding to coagulation factor ix and coagulation factor x
|
|
JP2019536823A
(ja)
|
2016-12-05 |
2019-12-19 |
ハンミ ファーマシューティカル カンパニー リミテッド |
免疫反応が弱化された結合体
|
|
WO2018104893A1
(en)
|
2016-12-06 |
2018-06-14 |
Glaxosmithkline Intellectual Property Development Limited |
Alpha4-beta7 antibodies with incrased fcrn binding and/or half-life
|
|
CN110300599B
(zh)
|
2016-12-07 |
2024-07-02 |
艾吉纳斯公司 |
抗体和其使用方法
|
|
DK3551660T5
(da)
|
2016-12-07 |
2024-09-02 |
Agenus Inc |
Anti-ctla-4-antistoffer og fremgangsmåder til anvendelse deraf
|
|
US20190352335A1
(en)
|
2016-12-19 |
2019-11-21 |
Hanmi Pharm. Co., Ltd. |
Brain targeting long-acting protein conjugate
|
|
IL317134A
(en)
|
2016-12-21 |
2025-01-01 |
Teneobio Inc |
An antibody containing only heavy chains that binds a human B-cell maturation antigen, a pharmaceutical composition containing the same, its use in the treatment of B-cell disorders and a method for its preparation
|
|
AU2017383232B2
(en)
|
2016-12-23 |
2024-09-12 |
Novartis Ag |
Factor XI antibodies and methods of use
|
|
IL267519B2
(en)
|
2016-12-23 |
2025-04-01 |
Novartis Ag |
Factor XI/XIA for use in the prevention, treatment, management, or reduction of the risk of stroke or thromboembolism in a patient with end-stage renal disease
|
|
MX2019008199A
(es)
|
2017-01-06 |
2019-11-25 |
Avidity Biosciences Llc |
Composiciones de acido nucleico polipeptido y metodos de induccion de la omision de exon.
|
|
TW201833140A
(zh)
|
2017-01-09 |
2018-09-16 |
美商莫瑞麥克製藥公司 |
抗fgfr抗體及使用方法
|
|
WO2018138591A1
(en)
|
2017-01-24 |
2018-08-02 |
Pfizer Inc. |
Calicheamicin derivatives and antibody drug conjugates thereof
|
|
CN110545849A
(zh)
|
2017-02-03 |
2019-12-06 |
韩美药品株式会社 |
具有增加的持续性的生理活性物质的缀合物及其应用
|
|
KR20180091773A
(ko)
|
2017-02-07 |
2018-08-16 |
한미약품 주식회사 |
비펩티드성 중합체 링커 화합물, 그 링커 화합물을 포함하는 결합체, 및 이들의 제조방법
|
|
KR102572663B1
(ko)
|
2017-02-08 |
2023-09-01 |
노파르티스 아게 |
Fgf21 모방 항체 및 이의 용도
|
|
CA3051839A1
(en)
|
2017-02-17 |
2018-08-23 |
Bristol-Myers Squibb Company |
Antibodies to alpha-synuclein and uses thereof
|
|
KR102867975B1
(ko)
|
2017-03-06 |
2025-10-14 |
알토 바이오사이언스 엘엘씨 |
Il-12 및 il-18로의 il-15-기반 융합
|
|
KR101941975B1
(ko)
|
2017-03-17 |
2019-01-25 |
고려대학교 산학협력단 |
Atpif1을 함유하는 당뇨 치료용 약학조성물
|
|
KR102629006B1
(ko)
|
2017-03-23 |
2024-01-25 |
한미약품 주식회사 |
인슐린 수용체와의 결합력이 감소된 인슐린 아날로그의 결합체 및 이의 용도
|
|
KR102648564B1
(ko)
|
2017-03-24 |
2024-03-19 |
씨젠 인크. |
글루쿠로니드 약물-링커의 제조 공정 및 그 중간물
|
|
US20190048055A1
(en)
|
2017-03-31 |
2019-02-14 |
Altor Bioscience Corporation |
Alt-803 in combination with anti-cd38 antibody for cancer therapies
|
|
JP2020513019A
(ja)
|
2017-04-05 |
2020-04-30 |
ノヴォ ノルディスク アー／エス |
オリゴマー伸長インスリン−Ｆｃコンジュゲート
|
|
TWI788340B
(zh)
|
2017-04-07 |
2023-01-01 |
美商必治妥美雅史谷比公司 |
抗icos促效劑抗體及其用途
|
|
EP3606952A1
(en)
|
2017-04-07 |
2020-02-12 |
Miltenyi Biotec GmbH |
POLYPEPTIDES WITH MUTANT HUMAN IgG4
|
|
KR20240017409A
(ko)
|
2017-04-13 |
2024-02-07 |
아게누스 인코포레이티드 |
항-cd137 항체 및 이의 사용 방법
|
|
JOP20190248A1
(ar)
|
2017-04-21 |
2019-10-20 |
Amgen Inc |
بروتينات ربط مولد ضد trem2 واستخداماته
|
|
CN110506056A
(zh)
*
|
2017-04-21 |
2019-11-26 |
斯塔滕生物技术有限公司 |
抗apoc3抗体和其使用方法
|
|
EP3615564A1
(en)
|
2017-04-24 |
2020-03-04 |
Alexion Pharmaceuticals, Inc. |
Antibody immune cell inhibitor fusion proteins
|
|
CA3060206A1
(en)
|
2017-04-27 |
2018-11-01 |
Seattle Genetics, Inc. |
Quaternized nicotinamide adenine dinucleotide salvage pathway inhibitor conjugates
|
|
LT3618863T
(lt)
|
2017-05-01 |
2023-10-10 |
Agenus Inc. |
Anti-tigit antikūnai ir jų panaudojimo būdai
|
|
EP3625251A1
(en)
|
2017-05-15 |
2020-03-25 |
University Of Rochester |
Broadly neutralizing anti-influenza monoclonal antibody and uses thereof
|
|
WO2018215937A1
(en)
|
2017-05-24 |
2018-11-29 |
Novartis Ag |
Interleukin-7 antibody cytokine engrafted proteins and methods of use in the treatment of cancer
|
|
JOP20190271A1
(ar)
|
2017-05-24 |
2019-11-21 |
Novartis Ag |
بروتينات مطعّمة بسيتوكين- الجسم المضاد وطرق الاستخدام للاضطرابات المتعلقة بالمناعة
|
|
WO2018215938A1
(en)
|
2017-05-24 |
2018-11-29 |
Novartis Ag |
Antibody-cytokine engrafted proteins and methods of use
|
|
MY206158A
(en)
|
2017-05-24 |
2024-12-02 |
Novartis Ag |
Antibody-cytokine engrafted proteins and methods of use in the treatment of cancer
|
|
US20200299400A1
(en)
|
2017-05-25 |
2020-09-24 |
Bristol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
|
WO2018229715A1
(en)
|
2017-06-16 |
2018-12-20 |
Novartis Ag |
Compositions comprising anti-cd32b antibodies and methods of use thereof
|
|
CN110945026B
(zh)
|
2017-06-20 |
2024-03-19 |
特纳奥尼股份有限公司 |
仅有重链的抗bcma抗体
|
|
KR20250007003A
(ko)
|
2017-06-20 |
2025-01-13 |
테네오바이오, 인코포레이티드 |
항-bcma 중쇄-단독 항체
|
|
AU2018295994B2
(en)
|
2017-07-07 |
2025-02-06 |
Hanmi Pharm. Co., Ltd. |
Novel therapeutic enzyme fusion protein and use thereof
|
|
GB201711809D0
(en)
|
2017-07-21 |
2017-09-06 |
Governors Of The Univ Of Alberta |
Antisense oligonucleotide
|
|
DK3658184T5
(da)
|
2017-07-27 |
2024-08-26 |
Alexion Pharma Inc |
Højkoncentrerede anti-c5-antistofformuleringer
|
|
US11306144B2
(en)
|
2017-08-25 |
2022-04-19 |
Five Prime Therapeutics, Inc. |
B7-H4 antibodies and methods of use thereof
|
|
JP2020533971A
(ja)
|
2017-08-28 |
2020-11-26 |
アルター・バイオサイエンス・コーポレーション |
Ｉｌ−１５をベースとするｉｌ−７及びｉｌ−２１への融合物
|
|
EP3681908A1
(en)
|
2017-09-13 |
2020-07-22 |
Teneobio, Inc. |
Heavy chain antibodies binding to ectoenzymes
|
|
KR20190036956A
(ko)
|
2017-09-28 |
2019-04-05 |
한미약품 주식회사 |
지속형 단쇄 인슐린 아날로그 및 이의 결합체
|
|
EA202090571A1
(ru)
|
2017-09-28 |
2020-07-30 |
Ханми Фарм. Ко., Лтд. |
Конъюгаты производных glp-2 пролонгированного действия
|
|
WO2019066603A1
(ko)
|
2017-09-29 |
2019-04-04 |
한미약품 주식회사 |
효력이 향상된 지속성 단백질 결합체
|
|
US11357861B2
(en)
|
2017-09-29 |
2022-06-14 |
Hanmi Pharm. Co., Ltd |
Protein complex comprising non-peptidyl polymer-coupled fatty acid derivative compound as linker and preparation method therefor
|
|
EP3691657A4
(en)
|
2017-10-04 |
2021-07-21 |
Avidity Biosciences, Inc. |
NUCLEIC ACID POLYPEPTIDE COMPOSITIONS AND USES THEREOF
|
|
EP3694552A1
(en)
|
2017-10-10 |
2020-08-19 |
Tilos Therapeutics, Inc. |
Anti-lap antibodies and uses thereof
|
|
WO2019073069A1
(en)
|
2017-10-13 |
2019-04-18 |
Boehringer Ingelheim International Gmbh |
HUMAN ANTIBODIES AGAINST THOMSEN-NEW ANTIGEN (TN)
|
|
US10640508B2
(en)
|
2017-10-13 |
2020-05-05 |
Massachusetts Institute Of Technology |
Diazene directed modular synthesis of compounds with quaternary carbon centers
|
|
WO2019081983A1
(en)
|
2017-10-25 |
2019-05-02 |
Novartis Ag |
CD32B TARGETING ANTIBODIES AND METHODS OF USE
|
|
CN118512588A
(zh)
|
2017-10-26 |
2024-08-20 |
亚力兄制药公司 |
用于治疗阵发性夜间性血红蛋白尿(pnh)和非典型溶血性尿毒症综合征(ahus)的抗c5抗体的剂量和施用
|
|
PE20210119A1
(es)
|
2017-10-31 |
2021-01-19 |
Staten Biotechnology B V |
Anticuerpos anti-apoc3 y metodos de uso de estos
|
|
EP4640703A3
(en)
|
2017-11-14 |
2026-04-08 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-c1s antibodies and methods of use
|
|
AU2018378812B2
(en)
|
2017-12-06 |
2025-05-22 |
Avidity Biosciences, Inc. |
Compositions and methods of treating muscle atrophy and myotonic dystrophy
|
|
CA3081144A1
(en)
|
2017-12-08 |
2019-06-13 |
Argenx Bvba |
Use of fcrn antagonists for treatment of generalized myasthenia gravis
|
|
CN111511910B
(zh)
|
2017-12-22 |
2024-11-08 |
韩美药品株式会社 |
具有新颖结构的治疗酶融合蛋白及其用途
|
|
CN111683966B
(zh)
|
2017-12-22 |
2023-07-11 |
特尼奥生物股份有限公司 |
与cd22结合的重链抗体
|
|
WO2019123427A1
(en)
|
2017-12-22 |
2019-06-27 |
Novartis Ag |
Methods of treating metabolic disorders with fgf21 variants
|
|
WO2019129054A1
(zh)
|
2017-12-27 |
2019-07-04 |
信达生物制药(苏州)有限公司 |
三链抗体、其制备方法及其用途
|
|
JP2021508479A
(ja)
|
2017-12-27 |
2021-03-11 |
テネオバイオ， インコーポレイテッド |
ヘテロ二量体特異的抗体上のｃｄ３デルタ及びｃｄ３イプシロン
|
|
CN111788227B
(zh)
|
2017-12-27 |
2025-02-25 |
百时美施贵宝公司 |
抗cd40抗体及其用途
|
|
SG11202006610YA
(en)
|
2018-01-12 |
2020-08-28 |
Amgen Inc |
Pac1 antibodies and uses thereof
|
|
EP3737700A1
(en)
|
2018-01-12 |
2020-11-18 |
Bristol-Myers Squibb Company |
Antibodies against tim3 and uses thereof
|
|
SG11202007540SA
(en)
|
2018-02-20 |
2020-09-29 |
Seattle Genetics Inc |
Hydrophobic auristatin f compounds and conjugates thereof
|
|
BR112020016986A2
(pt)
|
2018-02-21 |
2021-03-02 |
Five Prime Therapeutics, Inc. |
formulações de anticorpo contra b7-h4
|
|
MX2020009069A
(es)
*
|
2018-03-01 |
2020-10-08 |
Igm Biosciences Inc |
Mutaciones de fc de igm y de la cadena j que afectan la semivida de igm en suero.
|
|
KR20200144094A
(ko)
|
2018-03-02 |
2020-12-28 |
파이브 프라임 테라퓨틱스, 인크. |
B7-h4 항체 및 이의 사용 방법
|
|
EP3768715A1
(en)
|
2018-03-23 |
2021-01-27 |
Bristol-Myers Squibb Company |
Antibodies against mica and/or micb and uses thereof
|
|
US11168138B2
(en)
|
2018-03-26 |
2021-11-09 |
Altor Bioscience, Llc |
Anti-PDL1, IL-15 and TGF-beta receptor combination molecules
|
|
CN110305210B
(zh)
|
2018-03-27 |
2023-02-28 |
信达生物制药(苏州)有限公司 |
新型抗体分子、其制备方法及其用途
|
|
WO2019184909A1
(zh)
|
2018-03-27 |
2019-10-03 |
信达生物制药(苏州)有限公司 |
新型抗体分子、其制备方法及其用途
|
|
EP3777894A4
(en)
|
2018-03-30 |
2022-04-06 |
Hanmi Pharm. Co., Ltd. |
ANTI-BRAIN DIRECTIONAL LONG-ACTING PROTEIN CONJUGATE, METHOD OF MANUFACTURE THEREOF AND COMPOSITION THEREOF
|
|
WO2019195126A1
(en)
|
2018-04-02 |
2019-10-10 |
Bristol-Myers Squibb Company |
Anti-trem-1 antibodies and uses thereof
|
|
CN110396133B
(zh)
|
2018-04-25 |
2021-07-23 |
免疫靶向有限公司 |
一种以白介素12为活性成分的融合蛋白型药物前体
|
|
KR102194644B1
(ko)
|
2018-04-26 |
2020-12-24 |
주식회사 굳티셀 |
신규한 융합 단백질 및 이를 포함하는 암의 예방 또는 치료용 약학적 조성물
|
|
CA3096703A1
(en)
|
2018-05-03 |
2019-11-07 |
University Of Rochester |
Anti-influenza neuraminidase monoclonal antibodies and uses thereof
|
|
CA3099450A1
(en)
|
2018-05-08 |
2019-11-14 |
Amgen Inc. |
Bispecific antibodies with cleavable c-terminal charge-paired tags
|
|
TWI869346B
(zh)
|
2018-05-30 |
2025-01-11 |
瑞士商諾華公司 |
Ｅｎｔｐｄ２抗體、組合療法、及使用該等抗體和組合療法之方法
|
|
EP3802593B1
(en)
|
2018-05-31 |
2024-09-11 |
Alexion Pharmaceuticals, Inc. |
Dosage and administration of anti-c5 antibodies for treatment of paroxysmal nocturnal hemoglobinuria (pnh) in pediatric patients
|
|
KR102870868B1
(ko)
|
2018-06-01 |
2025-10-15 |
노파르티스 아게 |
Bcma에 대한 결합 분자 및 이의 용도
|
|
EP3802603A1
(en)
|
2018-06-04 |
2021-04-14 |
Alexion Pharmaceuticals, Inc. |
Dosage and administration of anti-c5 antibodies for treatment of atypical hemolytic uremic syndrome (ahus) in pediatric patients
|
|
TWI851577B
(zh)
|
2018-06-07 |
2024-08-11 |
美商思進公司 |
喜樹鹼結合物
|
|
US12202900B2
(en)
|
2018-06-08 |
2025-01-21 |
argenx BV |
Compositions and methods for treating immune thrombocytopenia
|
|
TWI848953B
(zh)
|
2018-06-09 |
2024-07-21 |
德商百靈佳殷格翰國際股份有限公司 |
針對癌症治療之多特異性結合蛋白
|
|
WO2019241628A1
(en)
|
2018-06-15 |
2019-12-19 |
Proclara Biosciences, Inc. |
General amyloid interaction motif (gaim)
|
|
KR20250156190A
(ko)
|
2018-06-22 |
2025-10-31 |
큐진 인크. |
인터루킨-2 변이체 및 이의 사용 방법
|
|
US12312394B2
(en)
|
2018-06-28 |
2025-05-27 |
Alexion Pharmaceuticals, Inc. |
Methods of producing anti-C5 antibodies
|
|
CN112740043A
(zh)
|
2018-07-20 |
2021-04-30 |
皮埃尔法布雷医药公司 |
Vista受体
|
|
BR112020024074A2
(pt)
|
2018-07-20 |
2021-02-17 |
Teneobio, Inc. |
anticorpos de cadeia pesada com ligação a cd19
|
|
US20210347849A1
(en)
|
2018-07-24 |
2021-11-11 |
Good T Cells, Inc. |
Composition for Preventing or Treating Immune-Related Diseases
|
|
SG11202100928QA
(en)
|
2018-08-02 |
2021-02-25 |
Dyne Therapeutics Inc |
Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
|
|
KR102259473B1
(ko)
|
2018-08-10 |
2021-06-02 |
추가이 세이야쿠 가부시키가이샤 |
항cd137 항원 결합 분자 및 그의 사용
|
|
WO2020037120A1
(en)
|
2018-08-16 |
2020-02-20 |
Nantbio, Inc. |
Il7-il15 txm compositions and methods
|
|
SG11202102713TA
(en)
|
2018-09-21 |
2021-04-29 |
Teneobio Inc |
Methods for purifying heterodimeric, multispecific antibodies
|
|
CN110964116A
(zh)
|
2018-09-26 |
2020-04-07 |
北京辅仁瑞辉生物医药研究院有限公司 |
GLP1-Fc融合蛋白及其缀合物
|
|
BR112021005585A2
(pt)
|
2018-09-27 |
2021-06-29 |
Celgene Corporation |
proteínas de ligação a sirpa e métodos de uso das mesmas
|
|
KR20210070300A
(ko)
|
2018-10-03 |
2021-06-14 |
스태튼 바이오테크놀로지 비.브이. |
사람 및 시노몰구스 ApoC3에 대해 특이적인 항체 및 이의 사용 방법
|
|
WO2020071865A1
(ko)
|
2018-10-04 |
2020-04-09 |
한미약품 주식회사 |
글루카곤 및 이를 포함하는 조합물의 치료학적 용도
|
|
WO2020074544A1
(en)
|
2018-10-10 |
2020-04-16 |
Novo Nordisk A/S |
Oligomer extended insulin-fc conjugates and their medical use
|
|
CN113164780A
(zh)
|
2018-10-10 |
2021-07-23 |
泰洛斯治疗公司 |
抗lap抗体变体及其用途
|
|
UY38407A
(es)
|
2018-10-15 |
2020-05-29 |
Novartis Ag |
Anticuerpos estabilizadores de trem2
|
|
TWI824043B
(zh)
|
2018-10-25 |
2023-12-01 |
西班牙商瑪製藥股份有限公司 |
藥物抗體共軛物
|
|
KR20210086651A
(ko)
|
2018-10-26 |
2021-07-08 |
테네오바이오, 인코포레이티드 |
Cd38에 결합하는 중쇄 항체
|
|
MY195550A
(en)
|
2018-10-29 |
2023-01-31 |
Hoffmann La Roche |
Antibody Formulation
|
|
EP3873602B1
(en)
|
2018-10-30 |
2023-12-06 |
Alexion Pharmaceuticals, Inc. |
Subcutaneous dosage and administration of anti-c5 antibodies for treatment of paroxysmal nocturnal hemoglobinuria (pnh)
|
|
CN113316590B
(zh)
|
2018-11-16 |
2025-02-28 |
百时美施贵宝公司 |
抗nkg2a抗体及其用途
|
|
EP3887397A1
(en)
|
2018-11-28 |
2021-10-06 |
Bristol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
|
CN113453703A
(zh)
|
2018-12-21 |
2021-09-28 |
韩美药品株式会社 |
包括胰岛素和对胰高血糖素和glp-1和gip受体均具有活性的三重激动剂的药物组合物
|
|
IL312067B2
(en)
|
2018-12-21 |
2025-08-01 |
Avidity Biosciences Inc |
Anti-transferrin receptor antibodies and uses thereof
|
|
KR20200078414A
(ko)
|
2018-12-21 |
2020-07-01 |
한미약품 주식회사 |
인슐린 및 글루카곤을 포함하는 약학 조성물
|
|
CN113396162B
(zh)
|
2019-01-22 |
2024-08-16 |
百时美施贵宝公司 |
抗IL-7Rα亚基的抗体及其用途
|
|
MX2021010003A
(es)
|
2019-02-26 |
2021-12-10 |
Inspirna Inc |
Anticuerpos anti-mertk de alta afinidad y usos de los mismos.
|
|
WO2020206330A1
(en)
|
2019-04-05 |
2020-10-08 |
Teneobio, Inc. |
Heavy chain antibodies binding to psma
|
|
KR102524577B1
(ko)
|
2019-04-22 |
2023-04-21 |
전남대학교산학협력단 |
플라젤린 융합 단백질 및 이의 용도
|
|
WO2020219820A1
(en)
|
2019-04-25 |
2020-10-29 |
Avidity Biosciences, Inc. |
Nucleic acid compositions and methods of multi-exon skipping
|
|
CA3138550A1
(en)
|
2019-04-30 |
2020-11-05 |
Target Discovery Merger Sub II, LLC |
Cancer associated antibody compositions and methods of use
|
|
IL287938B2
(en)
|
2019-05-10 |
2025-07-01 |
Takeda Pharmaceuticals Co |
Antibody-drug conjugates
|
|
EP4696320A2
(en)
|
2019-05-15 |
2026-02-18 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-c1s antibody
|
|
US12037378B2
(en)
|
2019-05-21 |
2024-07-16 |
Novartis Ag |
Variant CD58 domains and uses thereof
|
|
JP7489407B2
(ja)
|
2019-05-21 |
2024-05-23 |
ノバルティス アーゲー |
Ｃｄ１９結合分子及びその使用
|
|
JP7784898B2
(ja)
|
2019-05-24 |
2025-12-12 |
サノフイ |
全身性硬化症を治療するための方法
|
|
JP7500619B2
(ja)
|
2019-05-30 |
2024-06-17 |
アムジエン・インコーポレーテツド |
抗体の二量体化を促進するためのヒンジ領域の操作
|
|
US12006499B2
(en)
|
2019-06-06 |
2024-06-11 |
Avidity Biosciences, Inc. |
Una amidites and uses thereof
|
|
CN114375296A
(zh)
|
2019-06-06 |
2022-04-19 |
艾维迪提生物科学公司 |
核酸多肽组合物及其用途
|
|
JP7565951B2
(ja)
|
2019-06-07 |
2024-10-11 |
アルジェニクス ビーブイ |
皮下投与に好適なＦｃＲｎインヒビターの医薬製剤
|
|
CR20210622A
(es)
|
2019-06-14 |
2022-06-27 |
Teneobio Inc |
Anticuerpos multiespecíficos de cadena pesada que se unen a cd22 y cd3
|
|
DK3936142T3
(da)
|
2019-06-28 |
2024-03-25 |
Hanmi Pharmaceutical Co Ltd |
Tredobbelt agonist med aktivitet med hensyn til alle glucagon-, GLP-1- og GLP-receptorer til behandling af leversygdom
|
|
US20220363770A1
(en)
|
2019-06-28 |
2022-11-17 |
Amgen Inc. |
Anti-cgrp receptor/anti-pac1 receptor bispecific antigen binding proteins
|
|
CN114174536B
(zh)
|
2019-07-15 |
2026-03-27 |
百时美施贵宝公司 |
抗trem-1抗体及其用途
|
|
WO2021011681A1
(en)
|
2019-07-15 |
2021-01-21 |
Bristol-Myers Squibb Company |
Antibodies against human trem-1 and uses thereof
|
|
US12558431B2
(en)
|
2019-07-18 |
2026-02-24 |
Hanmi Pharm. Co., Ltd. |
Method of preparing protein conjugate
|
|
AU2019457235C1
(en)
|
2019-07-18 |
2022-12-22 |
Hanmi Pharm. Co., Ltd. |
Method for preparing long-acting drug conjugate through preparation of novel intermediate
|
|
WO2021022304A2
(en)
|
2019-07-30 |
2021-02-04 |
Qlsf Biotherapeutics, Inc. |
MULTISPECIFIC BINDING COMPOUNDS THAT BIND TO LRRC15 AND CD3ε
|
|
US20220242962A1
(en)
|
2019-08-12 |
2022-08-04 |
Aptevo Research And Development Llc |
4-1bb and ox40 binding proteins and related compositions and methods, antibodies against 4-1bb, antibodies against ox40
|
|
TW202122420A
(zh)
|
2019-08-30 |
2021-06-16 |
美商艾吉納斯公司 |
抗ｃｄ９６抗體及其使用方法
|
|
WO2021043951A1
(en)
|
2019-09-05 |
2021-03-11 |
Pharma Mar, S.A. |
Drug antibody conjugates
|
|
CN114502590A
(zh)
|
2019-09-18 |
2022-05-13 |
诺华股份有限公司 |
Entpd2抗体、组合疗法、以及使用这些抗体和组合疗法的方法
|
|
TW202124446A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
與ｅｎｔｐｄ２抗體之組合療法
|
|
CN114728073B
(zh)
|
2019-09-19 |
2024-12-27 |
思进股份有限公司 |
药物从生物活性化合物的内化缀合物的选择性释放
|
|
KR20210040818A
(ko)
|
2019-10-04 |
2021-04-14 |
한미약품 주식회사 |
글루카곤, 및 glp-1 수용체 및 gip 수용체 이중 작용제를 포함하는 조성물 및 이의 치료학적 용도
|
|
CN114929284A
(zh)
|
2019-10-04 |
2022-08-19 |
西根公司 |
喜树碱肽缀合物
|
|
WO2021067820A1
(en)
|
2019-10-04 |
2021-04-08 |
Seagen Inc. |
Formulation of antibody-drug conjugate
|
|
CN115551594A
(zh)
|
2019-10-24 |
2022-12-30 |
米诺陶治疗公司 |
经细胞因子修饰的嵌合抗体及其使用方法
|
|
ES3040852T3
(en)
|
2019-11-08 |
2025-11-05 |
Amgen Inc |
Engineering charge pair mutations for pairing of hetero-igg molecules
|
|
AU2020386005A1
(en)
|
2019-11-19 |
2022-05-26 |
Amgen Inc. |
Novel multispecific antibody format
|
|
JP7807076B2
(ja)
|
2019-12-13 |
2026-01-27 |
キュージーン インコーポレイテッド |
新規インターロイキン－１５（ｉｌ－１５）融合タンパク質およびその使用
|
|
CN115023441A
(zh)
|
2019-12-18 |
2022-09-06 |
特诺福尔股份有限公司 |
与cd38结合的重链抗体
|
|
IL293640A
(en)
|
2019-12-20 |
2022-08-01 |
Amgen Inc |
CD40 antagonistic mesothelin-targeted multispecific antibody constructs for the treatment of solid tumors
|
|
GB201919061D0
(en)
|
2019-12-20 |
2020-02-05 |
Ucb Biopharma Sprl |
Multi-specific antibody
|
|
JP7846622B2
(ja)
|
2019-12-24 |
2026-04-15 |
ハンミ ファーマシューティカル カンパニー リミテッド |
Ｇｌｐ－２又はその結合体を含む、代謝性骨疾患の予防又は治療用薬学的組成物
|
|
JP2023509195A
(ja)
|
2020-01-08 |
2023-03-07 |
アルジェニクス ビーブイ |
天疱瘡症を治療する方法
|
|
MX2022008646A
(es)
|
2020-01-13 |
2022-08-10 |
Hanmi Pharm Ind Co Ltd |
Uso terapeutico de un conjugado de accion prolongada de un triple agonista que tiene actividad en todos los receptores de glucagon/glp-1/gip para enfermedades pulmonares.
|
|
WO2021173773A1
(en)
|
2020-02-25 |
2021-09-02 |
Mediboston, Inc. |
Camptothecin derivatives and conjugates thereof
|
|
WO2021188390A1
(en)
|
2020-03-19 |
2021-09-23 |
Avidity Biosciences, Inc. |
Compositions and methods of treating facioscapulohumeral muscular dystrophy
|
|
US11365239B2
(en)
|
2020-03-20 |
2022-06-21 |
Tsb Therapeutics (Beijing) Co., Ltd. |
Anti-SARS-COV-2 antibodies and uses thereof
|
|
HRP20240182T1
(hr)
|
2020-03-26 |
2024-04-26 |
Vanderbilt University |
Ljudska monoklonska protutijela za teški akutni respiratorni sindrom koronavirusa 2 (sars-cov-2)
|
|
WO2021195574A1
(en)
*
|
2020-03-27 |
2021-09-30 |
Alnylam Pharmaceuticals, Inc. |
Fc FRAGMENT OF IgG RECEPTOR AND TRANSPORTER (FCGRT) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
|
|
SI4126066T1
(sl)
|
2020-03-27 |
2026-04-30 |
Avidity Biosciences, Inc. |
Sestavki in postopki zdravljenja mišične distrofije
|
|
KR20210121585A
(ko)
|
2020-03-30 |
2021-10-08 |
한국세라믹기술원 |
반응성 및 안정성 그리고 항체회수가 향상된 z-도메인 및 칼시퀘스트린 융합단백질 및 이를 이용한 항체의 분리 및 정제 방법
|
|
WO2021202235A1
(en)
|
2020-04-01 |
2021-10-07 |
University Of Rochester |
Monoclonal antibodies against the hemagglutinin (ha) and neuraminidase (na) of influenza h3n2 viruses
|
|
WO2021201654A1
(ko)
|
2020-04-03 |
2021-10-07 |
한미약품 주식회사 |
Glp-2 유도체 또는 이의 지속형 결합체를 포함하는 방사선요법, 화학요법, 또는 이들의 조합으로 유발된 점막염의 예방 또는 치료용 약학적 조성물
|
|
EP4133269A1
(en)
*
|
2020-04-08 |
2023-02-15 |
F. Hoffmann-La Roche AG |
Large molecule unspecific clearance assay
|
|
US20230272056A1
(en)
|
2020-04-09 |
2023-08-31 |
Merck Sharp & Dohme Llc |
Affinity matured anti-lap antibodies and uses thereof
|
|
EP4139350A4
(en)
|
2020-04-20 |
2024-04-24 |
Genzyme Corporation |
Humanized anti-complement factor bb antibodies and uses thereof
|
|
EP4140496A4
(en)
|
2020-04-20 |
2024-05-22 |
Hanmi Pharm. Co., Ltd. |
Preventive or therapeutic pharmaceutical composition for hyperlipidemia comprising triple agonist acting on all of glucagon, glp-1 and gip receptors, or conjugate thereof, and preventive or therapeutic method
|
|
CN115427081B
(zh)
|
2020-04-21 |
2025-12-09 |
法马马有限公司 |
药物抗体共轭物
|
|
MX2021015024A
(es)
|
2020-04-28 |
2022-01-18 |
Univ Rockefeller |
Anticuerpos anti-sars-cov-2 ampliamente neutralizantes y métodos de uso de los mismos.
|
|
TW202330622A
(zh)
|
2020-04-29 |
2023-08-01 |
美商泰尼歐生物公司 |
具有經修飾重鏈恆定區之多特異性重鏈抗體
|
|
IL297601A
(en)
|
2020-04-29 |
2022-12-01 |
Teneobio Inc |
Multispecific heavy chain antibodies with modified heavy chain constant regions
|
|
CN115803057A
(zh)
|
2020-04-29 |
2023-03-14 |
特纳奥尼公司 |
治疗多发性骨髓瘤的方法
|
|
KR20230012539A
(ko)
|
2020-05-13 |
2023-01-26 |
디스크 메디슨, 인크. |
골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체
|
|
US20230192867A1
(en)
|
2020-05-15 |
2023-06-22 |
Bristol-Myers Squibb Company |
Antibodies to garp
|
|
TW202208423A
(zh)
|
2020-05-17 |
2022-03-01 |
英商阿斯特捷利康英國股份有限公司 |
Ｓａｒｓ－ｃｏｖ－２抗體及其選擇和使用方法
|
|
KR20210144606A
(ko)
|
2020-05-22 |
2021-11-30 |
한미약품 주식회사 |
글루카곤 유도체의 지속형 결합체의 액상 제제
|
|
MX2022014671A
(es)
|
2020-05-22 |
2023-02-13 |
Hanmi Pharm Ind Co Ltd |
Formulacion liquida de conjugado de glp-2 de accion prolongada.
|
|
WO2021235915A1
(ko)
|
2020-05-22 |
2021-11-25 |
한미약품 주식회사 |
액상 제제
|
|
BR112022023609A2
(pt)
|
2020-05-22 |
2023-02-07 |
Hanmi Pharm Ind Co Ltd |
Formulação líquida de conjugado de ação prolongada de agonista trigonal de glucagon, glp-1 e gip
|
|
PE20231082A1
(es)
|
2020-06-26 |
2023-07-17 |
Amgen Inc |
Muteinas de il-10 y proteinas de fusion de las mismas referencia cruzada a solicitudes relacionadas
|
|
CN116472049A
(zh)
|
2020-06-30 |
2023-07-21 |
特尼奥生物股份有限公司 |
与bcma结合的多特异性抗体
|
|
EP4183407A4
(en)
|
2020-07-15 |
2024-08-14 |
Hanmi Pharm. Co., Ltd. |
THERAPEUTIC USE OF A GLUCAGNONE DERIVATIVE OR CONJUGATE THEREOF FOR LIVER DISEASES
|
|
JP7846667B2
(ja)
|
2020-07-16 |
2026-04-15 |
レジェンド バイオテック アイルランド リミテッド |
Ｃｄ２０結合分子及びその使用
|
|
CA3186416A1
(en)
|
2020-07-17 |
2022-01-20 |
John A. Barrett |
Methods of treating chemotherapy induced neutropenia using fixed doses of g-csf protein complex
|
|
JP2023535382A
(ja)
|
2020-07-17 |
2023-08-17 |
ハンミ ファーマシューティカル カンパニー リミテッド |
三重作用性持続型結合体又は三重作用剤を含む組合せ物の治療学的用途
|
|
CN113968911B
(zh)
|
2020-07-24 |
2023-10-10 |
江苏晟斯生物制药有限公司 |
胰岛素-Fc融合蛋白及其应用
|
|
JP2023537470A
(ja)
|
2020-08-03 |
2023-09-01 |
ヤンセン バイオテツク，インコーポレーテツド |
ウイルス治療における多方向バイオ輸送のための材料及び方法
|
|
IL300376A
(en)
|
2020-08-06 |
2023-04-01 |
Bioverativ Usa Inc |
Inflammatory cytokines and fatigue in subjects with complement-mediated disease
|
|
US20220041694A1
(en)
|
2020-08-10 |
2022-02-10 |
Astrazeneca Uk Limited |
Sars-cov-2 antibodies for treatment and prevention of covid-19
|
|
EP4197560A4
(en)
|
2020-08-14 |
2025-11-26 |
Hanmi Pharmaceutical Co Ltd |
Pharmaceutical composition comprising a persistent triple activator conjugate used as the active ingredient.
|
|
EP4197550A4
(en)
|
2020-08-14 |
2025-10-08 |
Hanmi Pharmaceutical Co Ltd |
PHARMACEUTICAL COMPOSITION WITH HYPOTENSIVE EFFECT COMPRISING A TRIPLE ACTIVATOR WITH ACTIVITY FOR ALL GLUCAGON, GLP-1, AND GIP RECEPTORS
|
|
US20230322955A1
(en)
|
2020-08-20 |
2023-10-12 |
Amgen Inc. |
Antigen binding proteins with non-canonical disulfide in fab region
|
|
EP4257144A4
(en)
|
2020-09-25 |
2024-11-20 |
Hanmi Pharm. Co., Ltd. |
PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF BONE DISEASES, COMPRISING A TRIPLE AGONIST OR A RELATED CONJUGATE HAVING ACTIVITY WITH RESPECT TO ALL GLUCAGON, GLP-1 AND GLP RECEPTORS
|
|
JP2023543036A
(ja)
|
2020-09-25 |
2023-10-12 |
ハンミ ファーマシューティカル カンパニー リミテッド |
グルカゴン、ｇｌｐ－１及びｇｉｐ受容体の全てに対して活性を有する三重活性体またはその結合体の神経退行性疾患の治療用途
|
|
JP2023543043A
(ja)
|
2020-09-25 |
2023-10-12 |
ハンミ ファーマシューティカル カンパニー リミテッド |
グルカゴン、ｇｌｐ－１及びｇｉｐ受容体の全てに対して活性を有する三重活性体の持続型結合体の多発性硬化症の治療用途
|
|
US20230374162A1
(en)
|
2020-10-07 |
2023-11-23 |
Amgen Inc. |
Rational selection of building blocks for the assembly of multispecific antibodies
|
|
EP4230640A4
(en)
|
2020-10-16 |
2024-11-20 |
Hanmi Pharm. Co., Ltd. |
GLP-1/GIP DOUBLE AGONIST, LONG-ACTING CONJUGATE THEREOF AND PHARMACEUTICAL COMPOSITION THEREOF
|
|
EP4230639A4
(en)
|
2020-10-16 |
2025-01-15 |
Hanmi Pharm. Co., Ltd. |
GIP DERIVATIVE, LONG-ACTING CONJUGATE THEREOF AND PHARMACEUTICAL COMPOSITION THEREOF
|
|
WO2022080987A1
(ko)
|
2020-10-16 |
2022-04-21 |
한미약품 주식회사 |
글루카곤/glp-1/gip 삼중작용제 또는 이의 지속형 결합체를 포함하는 혈관염 예방 또는 치료용 약학적 조성물
|
|
TW202233226A
(zh)
|
2020-10-16 |
2022-09-01 |
南韓商韓美藥品股份有限公司 |
用於治療呼吸感染後遺症的三重升糖素／ｇｌｐ－１／ｇｉｐ受體促效劑
|
|
CA3191224A1
(en)
|
2020-10-16 |
2022-04-21 |
Shenda GU |
Multispecific binding compounds that bind to pd-l1
|
|
US20230381281A1
(en)
|
2020-10-16 |
2023-11-30 |
Hanmi Pharm. Co., Ltd. |
Pharmaceutical composition comprising glucagon/glp-1/gip triple agonist or long-acting conjugate thereof for preventing or treating lupus-related diseases
|
|
JP2023546089A
(ja)
|
2020-10-16 |
2023-11-01 |
ハンミ ファーマシューティカルズ カンパニー リミテッド |
Ｇｉｐ誘導体またはその持続型結合体を含むループス関連疾患の予防用または治療用の薬学的組成物
|
|
TW202227481A
(zh)
|
2020-11-04 |
2022-07-16 |
美國洛克菲勒大學 |
中和抗sars-cov-2抗體
|
|
CA3199095A1
(en)
|
2020-11-06 |
2022-05-12 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
|
IL302390A
(en)
|
2020-11-09 |
2023-06-01 |
Takeda Pharmaceuticals Co |
Drug antibody conjugates
|
|
WO2022103773A1
(en)
|
2020-11-10 |
2022-05-19 |
Amgen Inc. |
Novel linkers of multispecific antigen binding domains
|
|
AU2021378707A1
(en)
|
2020-11-13 |
2023-06-01 |
Hanmi Pharm. Co., Ltd. |
Use of therapeutic enzyme fusion protein in prevention and treatment of renal diseases caused by or accompanied by Fabry disease
|
|
US20230416714A1
(en)
|
2020-11-13 |
2023-12-28 |
Hanmi Pharm. Co., Ltd |
Use of therapeutic enzyme fusion protein in prevention and treatment of neuropathy caused by or accompanied by fabry disease
|
|
TW202233684A
(zh)
|
2020-11-18 |
2022-09-01 |
美商泰尼歐生物公司 |
結合於葉酸受體α之重鏈抗體
|
|
IL303328A
(en)
|
2020-12-01 |
2023-07-01 |
Aptevo Res & Development Llc |
Heterodimeric psma and cd3-binding bispecific antibodies
|
|
PE20231953A1
(es)
|
2020-12-07 |
2023-12-06 |
UCB Biopharma SRL |
Anticuerpos multiespecificos y combinaciones de anticuerpos
|
|
WO2022131889A1
(ko)
|
2020-12-16 |
2022-06-23 |
주식회사 굳티셀 |
Taci 단백질의 용도
|
|
KR20220092442A
(ko)
|
2020-12-24 |
2022-07-01 |
한미약품 주식회사 |
신규한 글루카곤, glp-1 및 gip 수용체 모두에 활성을 갖는 삼중활성체 및 이의 용도
|
|
KR20220092446A
(ko)
|
2020-12-24 |
2022-07-01 |
한미약품 주식회사 |
단장증후군의 예방 또는 치료를 위한 인슐린 분비 펩타이드 및 glp-2의 병용 요법
|
|
JP2024502832A
(ja)
|
2020-12-31 |
2024-01-23 |
アラマー バイオサイエンシーズ， インコーポレイテッド |
高親和性及び／または特異性を有する結合剤分子ならびにその製造及び使用方法
|
|
CA3202832A1
(en)
|
2020-12-31 |
2022-07-07 |
Romesh R. Subramanian |
Muscle targeting complexes and uses thereof for treating myotonic dystrophy
|
|
WO2022155324A1
(en)
|
2021-01-15 |
2022-07-21 |
The Rockefeller University |
Neutralizing anti-sars-cov-2 antibodies
|
|
CN116847868A
(zh)
|
2021-01-29 |
2023-10-03 |
韩美药品株式会社 |
用于预防或治疗肺部疾病的包括gip衍生物或其长效共轭物的药学组合物
|
|
US12521444B2
(en)
|
2021-02-25 |
2026-01-13 |
Fortvita Biologics Limited |
Anti-HER2 antibody-drug conjugates and uses thereof
|
|
KR20230148828A
(ko)
|
2021-02-25 |
2023-10-25 |
테네오바이오, 인코포레이티드 |
항-psma 항체 및 car-t 구조
|
|
US20240182597A1
(en)
|
2021-02-26 |
2024-06-06 |
Teneobio, Inc. |
Anti-muc1-c antibodies and car-t structures
|
|
CA3213625A1
(en)
|
2021-03-18 |
2022-09-22 |
Seagen Inc. |
Selective drug release from internalized conjugates of biologically active compounds
|
|
BR112023018676A2
(pt)
|
2021-03-18 |
2023-10-10 |
Seagen Inc |
Conjugado anticorpo-fármaco, composição farmacêutica, métodos de tratamento de uma doença ou condição e de um câncer, e, composição de conjugado ligante-fármaco
|
|
IL304365B2
(en)
|
2021-03-31 |
2025-04-01 |
Hanmi Pharmaceutical Co Ltd |
A novel conjugate of an IL2 immunostimulatory analog and method of preparation thereof
|
|
WO2022212645A1
(en)
|
2021-03-31 |
2022-10-06 |
Bioverativ Usa Inc. |
Reducing surgery-associated hemolysis in cold agglutinin disease patients
|
|
EP4314068A1
(en)
|
2021-04-02 |
2024-02-07 |
The Regents Of The University Of California |
Antibodies against cleaved cdcp1 and uses thereof
|
|
TW202304994A
(zh)
|
2021-04-02 |
2023-02-01 |
美商泰尼歐生物公司 |
促效性抗ｉｌ－２ｒ抗體及使用方法
|
|
KR20230166090A
(ko)
|
2021-04-06 |
2023-12-06 |
테네오바이오, 인코포레이티드 |
항-cd19 항체 및 car-t 구조체
|
|
CN117157094A
(zh)
|
2021-04-09 |
2023-12-01 |
韩美药品株式会社 |
包括胰高血糖素衍生物的用于预防或治疗慢性肾病的药物组合物
|
|
CN117337303A
(zh)
|
2021-04-16 |
2024-01-02 |
特尼奥生物股份有限公司 |
抗cd20抗体及car-t结构
|
|
MX2023012324A
(es)
|
2021-04-20 |
2023-10-30 |
Amgen Inc |
Distribucion de carga equilibrada en una direccion electrostatica del emparejamiento de cadenas en el conjunto de moleculas de igg multiespecificas y monovalentes.
|
|
US20250197525A1
(en)
|
2021-04-28 |
2025-06-19 |
Minotaur Therapeutics, Inc. |
Humanized chimeric bovine antibodies and methods of use
|
|
EP4334343A2
(en)
|
2021-05-06 |
2024-03-13 |
The Rockefeller University |
Neutralizing anti-sars- cov-2 antibodies and methods of use thereof
|
|
WO2022263357A1
(en)
|
2021-06-14 |
2022-12-22 |
Argenx Iip Bv |
Anti-il-9 antibodies and methods of use thereof
|
|
WO2022271987A1
(en)
|
2021-06-23 |
2022-12-29 |
TeneoFour, Inc. |
Anti-cd38 antibodies and epitopes of same
|
|
AU2022297535A1
(en)
|
2021-06-25 |
2024-01-04 |
Amgen Inc. |
Treatment of cardiovascular disease with trem-1 antigen binding proteins
|
|
KR20230004135A
(ko)
|
2021-06-30 |
2023-01-06 |
한미약품 주식회사 |
글루카곤, glp-1 및 gip 수용체 모두에 활성을 갖는 삼중 활성체를 포함하는 조합물의 치료학적 용도
|
|
WO2023004197A1
(en)
|
2021-07-23 |
2023-01-26 |
Teneoten, Inc. |
Heavy chain antibodies binding to hepatitis b surface antigen
|
|
AU2022338282A1
(en)
|
2021-09-02 |
2024-03-14 |
Djs Antibodies Ltd |
Polypeptides
|
|
CN118265544A
(zh)
|
2021-09-16 |
2024-06-28 |
艾维迪提生物科学公司 |
治疗面肩肱型肌营养不良的组合物和方法
|
|
WO2023056240A2
(en)
|
2021-09-28 |
2023-04-06 |
Frontaim Biomedicines, Inc. |
Multiple formats of molecular complexes
|
|
AU2022358522A1
(en)
|
2021-09-30 |
2024-03-28 |
Seagen Inc. |
B7-h4 antibody-drug conjugates for the treatment of cancer
|
|
MX2024004550A
(es)
|
2021-10-14 |
2024-04-29 |
Teneobio Inc |
Proteinas de union a la mesotelina y usos de las mismas.
|
|
TW202342095A
(zh)
|
2021-11-05 |
2023-11-01 |
英商阿斯特捷利康英國股份有限公司 |
用於治療和預防ｃｏｖｉｄ—１９之組成物
|
|
JP2024540480A
(ja)
|
2021-11-17 |
2024-10-31 |
ディスク・メディシン・インコーポレイテッド |
腎臓疾患の貧血を処置する方法
|
|
KR20230095665A
(ko)
|
2021-12-22 |
2023-06-29 |
한미약품 주식회사 |
간 표적 약물 및 이의 용도
|
|
KR20230095666A
(ko)
|
2021-12-22 |
2023-06-29 |
한미약품 주식회사 |
간 표적 물질 및 이의 용도
|
|
UY40097A
(es)
|
2022-01-07 |
2023-07-14 |
Johnson & Johnson Entpr Innovation Inc |
Materiales y métodos de proteínas de unión a il-1b
|
|
US20250333485A1
(en)
|
2022-01-27 |
2025-10-30 |
The Rockefeller University |
Broadly neutralizing anti-sars-cov-2 antibodies targeting the n-terminal domain of the spike protein and methods of use thereof
|
|
TW202342510A
(zh)
|
2022-02-18 |
2023-11-01 |
英商Ｒｑ生物科技有限公司 |
抗體
|
|
WO2023173084A1
(en)
|
2022-03-11 |
2023-09-14 |
University Of Rochester |
Cyclopeptibodies and uses thereof
|
|
WO2023178289A2
(en)
|
2022-03-17 |
2023-09-21 |
Seagen Inc. |
Camptothecin conjugates
|
|
US12071621B2
(en)
|
2022-04-05 |
2024-08-27 |
Avidity Biosciences, Inc. |
Anti-transferrin receptor antibody-PMO conjugates for inducing DMD exon 44 skipping
|
|
JP2025513345A
(ja)
|
2022-04-18 |
2025-04-24 |
ハンミ ファーマシューティカル カンパニー リミテッド |
腸疾患の予防又は治療のためのＧＬＰ－２と、インスリン分泌ペプチド、ＴＮＦα抑制剤、又はその両方の併用療法
|
|
IL316174A
(en)
|
2022-04-26 |
2024-12-01 |
Novartis Ag |
Multiple specific antibodies targeting IL-13 and IL-18
|
|
US20250289871A1
(en)
|
2022-04-29 |
2025-09-18 |
Astrazeneca Uk Limited |
Sars-cov-2 antibodies and methods of using the same
|
|
CN119698429A
(zh)
|
2022-06-15 |
2025-03-25 |
阿根思有限公司 |
Fcrn结合分子及使用方法
|
|
US20240117021A1
(en)
|
2022-06-15 |
2024-04-11 |
Bioverativ Usa Inc. |
Anti-complement c1s antibody formulation
|
|
CA3260415A1
(en)
|
2022-06-24 |
2023-12-28 |
Bioverativ Usa Inc. |
METHODS OF TREATMENT FOR COMPLEMENT-MEDICATED DISEASES
|
|
JP2025523583A
(ja)
|
2022-07-01 |
2025-07-23 |
アルク－アベーロ アクティーゼルスカブ |
ＩｇＥ－ＦｃＥＲＩのディスプレーサー
|
|
JP2025525530A
(ja)
|
2022-07-15 |
2025-08-05 |
ヤンセン バイオテツク，インコーポレーテツド |
抗原結合可変領域の改善された生物工学による対合のための材料及び方法
|
|
TW202412762A
(zh)
|
2022-07-27 |
2024-04-01 |
香港商祐方有限公司 |
奧瑞他汀衍生物及其結合物
|
|
US20260035478A1
(en)
|
2022-07-27 |
2026-02-05 |
Teneobio, Inc. |
Mesothelin binding proteins and uses thereof
|
|
KR20250058123A
(ko)
|
2022-07-29 |
2025-04-29 |
리제너론 파마슈티칼스 인코포레이티드 |
항-TfR:페이로드 융합 및 이의 사용 방법
|
|
CN120659627A
(zh)
|
2022-07-29 |
2025-09-16 |
瑞泽恩制药公司 |
用于转铁蛋白受体（tfr）介导的脑和肌肉递送的组合物和方法
|
|
CA3263388A1
(en)
|
2022-07-29 |
2024-02-01 |
Regeneron Pharmaceuticals, Inc. |
VIRAL PARTICLES RETRIBUTED TO TRANSFERRIN RECEPTOR 1
|
|
US11773160B1
(en)
|
2022-08-05 |
2023-10-03 |
Anaveon AG |
Immune-stimulating IL-2 fusion proteins
|
|
CA3261708A1
(en)
|
2022-08-09 |
2024-02-15 |
Qlsf Biotherapeutics, Inc. |
ANTIBODIES BINDING TO CLEC12A
|
|
WO2024228717A2
(en)
|
2022-09-07 |
2024-11-07 |
Quantitative Biosciences, Inc. |
Fentanyl-specific single variable-domain antibodies and use in a continuous agglutination assay
|
|
WO2024067401A1
(zh)
|
2022-09-26 |
2024-04-04 |
中美华世通生物医药科技(武汉)股份有限公司 |
包含Fc-高级脂肪酸链的超长效平台
|
|
EP4598958A1
(en)
|
2022-10-05 |
2025-08-13 |
Amgen Inc. |
Combination therapies comprising t-cell redirecting therapies and agonistic anti-il-2r antibodies or fragments thereof
|
|
EP4612184A1
(en)
|
2022-11-04 |
2025-09-10 |
Regeneron Pharmaceuticals, Inc. |
Calcium voltage-gated channel auxiliary subunit gamma 1 (cacng1) binding proteins and cacng1-mediated delivery to skeletal muscle
|
|
AU2023379451A1
(en)
|
2022-11-14 |
2025-05-01 |
Regeneron Pharmaceuticals, Inc. |
Anti-fgfr3 antibodies and antigen-binding fragments and methods of use thereof
|
|
KR20250116795A
(ko)
|
2022-11-14 |
2025-08-01 |
리제너론 파마슈티칼스 인코포레이티드 |
별아교세포로의 섬유아세포 성장 인자 수용체 3-매개된 전달을 위한 조성물 및 방법
|
|
WO2024129756A1
(en)
|
2022-12-13 |
2024-06-20 |
Seagen Inc. |
Site-specific engineered cysteine antibody drug conjugates
|
|
WO2024130158A1
(en)
|
2022-12-16 |
2024-06-20 |
Modernatx, Inc. |
Lipid nanoparticles and polynucleotides encoding extended serum half-life interleukin-22 for the treatment of metabolic disease
|
|
CN120475959A
(zh)
|
2022-12-23 |
2025-08-12 |
韩美药品株式会社 |
包含免疫活性白细胞介素2类似物缀合物的制剂
|
|
CN120435309A
(zh)
|
2022-12-23 |
2025-08-05 |
韩美药品株式会社 |
含有glp-2衍生物或其长效缀合物的用于预防或治疗移植物抗宿主病的药物组合物
|
|
WO2024150074A2
(en)
|
2023-01-13 |
2024-07-18 |
Takeda Pharmaceutical Company Limited |
Coronavirus antibodies and therapeutic uses thereof
|
|
AU2024226156A1
(en)
|
2023-02-21 |
2025-08-28 |
Teneobio, Inc. |
C-kit binding proteins, chimeric antigen receptors, and uses thereof
|
|
KR20250158054A
(ko)
|
2023-03-02 |
2025-11-05 |
알로이 테라퓨틱스, 인크. |
항-cd22 항체 및 이의 용도
|
|
EP4678180A1
(en)
|
2023-03-07 |
2026-01-14 |
Hanmi Pharm. Co., Ltd. |
Pharmaceutical composition for preventing or treating cancer including interleukin 2 analog or conjugate thereof
|
|
WO2024186143A1
(ko)
|
2023-03-07 |
2024-09-12 |
한미약품 주식회사 |
암의 예방 또는 치료를 위한 인터루킨 2 아날로그 또는 이의 결합체 및 면역관문 억제제의 병용 요법
|
|
WO2024194685A2
(en)
|
2023-03-17 |
2024-09-26 |
Oxitope Pharma B.V. |
Anti-phosphocholine antibodies and methods of use thereof
|
|
KR20250173600A
(ko)
|
2023-03-17 |
2025-12-10 |
옥시토프 파마 비.브이. |
항-포스포콜린 항체 및 그 사용 방법
|
|
EP4688165A1
(en)
|
2023-03-31 |
2026-02-11 |
ALK-Abelló A/S |
Allergen binding antibodies suitable for treating tree pollen allergies
|
|
CN121152802A
(zh)
|
2023-04-18 |
2025-12-16 |
魁尔斯弗生物治疗股份有限公司 |
与ly6g6d结合的抗体
|
|
EP4735602A2
(en)
|
2023-06-27 |
2026-05-06 |
Atrium Therapeutics, Inc. |
Compositions and methods of using prkag2-targeting antibody-oligonucleotide conjugates abstract
|
|
AU2024308906A1
(en)
|
2023-06-30 |
2026-02-05 |
Atrium Therapeutics, Inc. |
Compositions and methods of using pln-targeting antibody-oligonucleotide conjugates
|
|
US20250049896A1
(en)
|
2023-07-28 |
2025-02-13 |
Regeneron Pharmaceuticals, Inc. |
Anti-tfr:acid sphingomyelinase for treatment of acid sphingomyelinase deficiency
|
|
IL326018A
(en)
|
2023-07-28 |
2026-03-01 |
Regeneron Pharma |
Introduction of anti-TFR:GAA and anti-CD63:GAA for the treatment of Pompe disease
|
|
WO2025037108A2
(en)
|
2023-08-15 |
2025-02-20 |
Board Of Trustees Of The Leland Stanford Junior University |
Modified thrombopoietin
|
|
WO2025046298A2
(en)
|
2023-09-01 |
2025-03-06 |
iTeos Belgium SA |
Anti-trem2 antibodies and methods of use
|
|
WO2025054181A1
(en)
|
2023-09-05 |
2025-03-13 |
Seagen Inc. |
Targeted degrader molecules and ligand drug conjugates thereof
|
|
WO2025059215A1
(en)
|
2023-09-12 |
2025-03-20 |
Aadigen, Llc |
Methods and compositions for treating or preventing cancer
|
|
TW202517301A
(zh)
|
2023-10-06 |
2025-05-01 |
美商思進公司 |
用ｂ７－ｈ４抗體－藥物結合物治療晚期實體腫瘤之方法
|
|
AR134171A1
(es)
|
2023-10-24 |
2025-12-10 |
Seagen Inc |
Compuestos quimioterapéuticos y métodos de uso
|
|
WO2025104604A1
(en)
|
2023-11-14 |
2025-05-22 |
Janssen Pharmaceuticals, Inc. |
Anti-respiratory syncytial virus antibodies and uses thereof
|
|
WO2025128343A1
(en)
|
2023-12-11 |
2025-06-19 |
Just-Evotec Biologics, Inc. |
Protein expression using trans-splicing and split selectable markers
|
|
WO2025133707A1
(en)
|
2023-12-19 |
2025-06-26 |
Vectory Therapeutics B.V. |
Anti-tdp-43 antibodies and uses thereof
|
|
WO2025133694A1
(en)
|
2023-12-20 |
2025-06-26 |
argenx BV |
Fcrn/hsa-binding molecules and methods of use
|
|
WO2025149947A1
(en)
|
2024-01-12 |
2025-07-17 |
Seagen Inc. |
Antibody-drug conjugates
|
|
WO2025155877A2
(en)
|
2024-01-18 |
2025-07-24 |
The Regents Of The University Of California |
Antibodies binding to pad4 and uses thereof
|
|
US12521446B2
(en)
|
2024-02-27 |
2026-01-13 |
Bristol-Myers Squibb Company |
Anti-CEACAM5 antibody drug conjugates
|
|
WO2025184208A1
(en)
|
2024-02-27 |
2025-09-04 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibodies and uses thereof
|
|
US20250276074A1
(en)
|
2024-03-01 |
2025-09-04 |
Prelude Therapeutics Incorporated |
Brm and brg1 targeting antibody-drug conjugates and methods of use thereof
|
|
US20250361297A1
(en)
|
2024-03-12 |
2025-11-27 |
Adaptam Therapeutics, S.L. |
Anti- siglec-15 binding molecules and methods of use
|
|
TW202602940A
(zh)
|
2024-04-09 |
2026-01-16 |
美商安進公司 |
激動性抗ｉｌ－２ｒｂｇ重鏈抗體
|
|
TW202544034A
(zh)
|
2024-05-06 |
2025-11-16 |
美商榮都醫療公司 |
結合至ｃｄ２８及ｎｅｃｔｉｎ－４之雙特異性抗體
|
|
WO2026006494A1
(en)
|
2024-06-25 |
2026-01-02 |
Alloy Therapeutics, Inc. |
Anti-cd3 antibodies and uses thereof
|
|
WO2026006495A1
(en)
|
2024-06-25 |
2026-01-02 |
Alloy Therapeutics, Inc. |
Anti-wt1/hla-a2 antibody and uses thereof
|
|
WO2026006492A2
(en)
|
2024-06-25 |
2026-01-02 |
Ypsilon Therapeutics, Inc. |
Anti-prame/hla-a2 antibodies and uses thereof
|
|
WO2026058155A1
(en)
|
2024-09-11 |
2026-03-19 |
Novartis Ag |
Antibodies targeting il-31
|