RU2418800C2 - Пирроло[2, 3-в]пиридиновые производные в качестве ингибиторов протеинкиназ - Google Patents

Пирроло[2, 3-в]пиридиновые производные в качестве ингибиторов протеинкиназ Download PDF

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RU2418800C2
RU2418800C2 RU2008100933/04A RU2008100933A RU2418800C2 RU 2418800 C2 RU2418800 C2 RU 2418800C2 RU 2008100933/04 A RU2008100933/04 A RU 2008100933/04A RU 2008100933 A RU2008100933 A RU 2008100933A RU 2418800 C2 RU2418800 C2 RU 2418800C2
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Russia
Prior art keywords
phenyl
pyridin
pyrrolo
carbonyl
difluoro
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RU2008100933/04A
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English (en)
Russian (ru)
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RU2008100933A (ru
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Прабха Н. ИБРАХИМ (US)
Прабха Н. Ибрахим
Дин Р. АРТИС (US)
Дин Р. Артис
Райан БРЕМЕР (US)
Райан Бремер
Шумейе МАМО (US)
Шумейе МАМО
Марика НЕСПИ (US)
Марика Неспи
Чао ЖАНГ (US)
Чао Жанг
Джиажонг ЖАНГ (US)
Джиажонг ЖАНГ
Йонг-Лианг ЖУ (US)
Йонг-Лианг Жу
Джеймс ЦАЙ (US)
Джеймс Цай
Клаус-Питер ХЕРТ (US)
Клаус-Питер ХЕРТ
Гидеон БОЛЛАГ (US)
Гидеон Боллаг
Уэйн СПЕВАК (US)
Уэйн СПЕВАК
Ханна ЧО (US)
Ханна Чо
Сэмьюэл Дж. ДЖИЛЛЕТ (US)
Сэмьюэл Дж. ДЖИЛЛЕТ
Гуоксиам ВУ (US)
Гуоксиам ВУ
Хонгьяо ЖУ (US)
Хонгьяо ЖУ
Шенгхуа ШИ (US)
Шенгхуа Ши
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Плекссикон, Инк.
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EA037372B1 (ru) * 2011-08-01 2021-03-22 Вертекс Фармасьютикалз Инкорпорейтед Ингибиторы репликации вирусов гриппа
US10723717B2 (en) 2016-12-23 2020-07-28 Arvinas Operations, Inc. Compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides
US11173211B2 (en) 2016-12-23 2021-11-16 Arvinas Operations, Inc. Compounds and methods for the targeted degradation of rapidly accelerated Fibrosarcoma polypeptides
RU2782458C2 (ru) * 2016-12-23 2022-10-27 Эрвинэс Оперейшнс, Инк. Соединения и способы нацеленного расщепления полипептидов быстропрогрессирующей фибросаркомы
US11986531B2 (en) 2016-12-23 2024-05-21 Arvinas Operations, Inc. Compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides
RU2795146C2 (ru) * 2017-01-31 2023-04-28 Эрвинэс Оперейшнс, Инк. Лиганды цереблона и бифункциональные соединения, содержащие их
RU2687107C1 (ru) * 2018-06-18 2019-05-07 федеральное государственное автономное образовательное учреждение высшего образования "Московский физико-технический институт (государственный университет)" Ингибитор braf киназы n-(3-(5-(4-хлорофенил)-1h-пиразоло[3,4-b]пиридин-3-карбонил)-2,4-дифторофенил) пропан-1-сульфонамид
US11883393B2 (en) 2019-12-19 2024-01-30 Arvinas Operations, Inc. Compounds and methods for the targeted degradation of androgen receptor
US11957759B1 (en) 2022-09-07 2024-04-16 Arvinas Operations, Inc. Rapidly accelerated fibrosarcoma (RAF) degrading compounds and associated methods of use

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